CN105902657A - Pharmaceutical preparation for treating functional dyspepsia, and preparation method of pharmaceutical preparation - Google Patents

Abstract

The invention discloses a pharmaceutical preparation for treating functional dyspepsia, and a preparation method of the pharmaceutical preparation. The pharmaceutical preparation for treating functional dyspepsia is prepared from the following materials in parts by weight: 10-15 parts of hawthorn fruits, 5-15 parts of tangerine peel, 5-10 parts of cortex magnoliae officinalis, 3-9 parts of rhizoma atractylodis, 3-6 parts of lotus plumule, 3-8 parts of white poria cocos, 0.5-2 parts of herba pogostemonis, 4-8 parts of fructus citri sarcodactylis, 10-20 parts of licorice root, 5-8 parts of fructus aurantii immaturus, 5-15 parts of radix puerariae, 20-30 parts of honey and 15-20 parts of rock candies. The effect of the pharmaceutical preparation is fully exerted by means of mutual compatibility of the medicines; the effective components of the medicine prepared by the method are maintained to the utmost extent; and the pharmaceutical preparation has a remarkable effect on treating functional dyspepsia, and is quick in response and free from toxic or side effect.

Description

A kind of pharmaceutical preparation treating functional dyspepsia FD and preparation method thereof

Technical field

The present invention relates to technical field of pharmaceuticals, be specifically related to a kind of pharmaceutical preparation treating functional dyspepsia FD and preparation method thereof.

Background technology

Functional dyspepsia FD, also known as indigestion, refers to have the malaise symptoms such as epigastric pain, big belly, early satiety, belch, poor appetite, Nausea and vomiting, gets rid of one group of clinical syndrome of the organic disease causing above-mentioned symptom on inspection.Symptom is sustainable or recurrent exerbation, and the course of disease is accumulative more than 12 weeks more than one month or in the December in past.Indigestion is the most modal a kind of FGID.

The cause of disease and the pathogenesis of functional dyspepsia FD are not fully understood, most scholars think that this disease is caused by many factors, generally acknowledge that its main pathogenesis is gastrointestinal motility disorders, gastric acid secretion exception, visceral perception allergy, and the effect of psychologic factors, dietary factor, helicobacter pylori infections and gastrointestinal hormone etc. is still in exploration.The selection of functional dyspepsia FD methods for the treatment of is experimental, and there is no a kind of method or medicine has the curative effect of affirmative to all of patient, also lacks objective reliable curative effect determinate standard.The basic principle for the treatment of is on the basis of the doctor-patient relationship setting up mutual trust, varies with each individual and takes individuation, complex treatment measure.At present, the Western medicine huge number for the treatment of indigestion illness, such as Domperidone, metoclopramide etc., although instant effect, good effect, but there is certain side effect, the advantage that traditional Chinese medicine ingredients is low with toxicity, toxic action is little, the market share incrementally increases, but be usually present curative effect not rapidly, the unconspicuous shortcoming of active ingredient.

Summary of the invention

For the deficiencies in the prior art, the invention provides a kind of pharmaceutical preparation treating functional dyspepsia FD so that instant effect, the feature having no side effect.

For realizing object above, the present invention is achieved by the following technical programs:

A kind of pharmaceutical preparation treating functional dyspepsia FD, is made up of the material of following weight portion: hawthorn 10-15 part, dried orange peel 5-15 part, bark of official magnolia 5-10 part, rhizoma atractylodis 3-9 part, lotus nut 3-6 part, PORIA ALBA 3-8 part, wrinkled giant hyssop 0.5-2 part, Buddha's hand 4-8 part, Radix Glycyrrhizae 10-20 part, long-pending real 5-8 part, root of kudzu vine 5-15 part, honey 20-30 part, rock sugar 15-20 part.

Preferably, the pharmaceutical preparation of described treatment functional dyspepsia FD, is made up of the material of following weight portion: hawthorn 12 parts, dried orange peel 8 parts, the bark of official magnolia 6 parts, rhizoma atractylodis 8 parts, lotus nut 5 parts, PORIA ALBA 7 parts, wrinkled giant hyssop 1.5 parts, Buddha's hand 6 parts, 15 parts of Radix Glycyrrhizae, long-pending reality 8 parts, the root of kudzu vine 12 parts, honey 28 parts, 18 parts of rock sugar.

Preferably, described hawthorn is charred FRUCTUS CRATAEGI.

Preferably, the described bark of official magnolia is that ginger processs the bark of official magnolia.

Preferably, the described dried immature fruit of citron orange is for frying the dried immature fruit of citron orange.

The preparation method of a kind of pharmaceutical preparation treating functional dyspepsia FD, comprises the following steps:

(1) after hawthorn, dried orange peel, the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, wrinkled giant hyssop, Buddha's hand, Radix Glycyrrhizae, long-pending reality, the root of kudzu vine being cleaned with clear water, then steep 1-2 hour with warm water；

(2) hawthorn in step (1), dried orange peel, the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, Buddha's hand, Radix Glycyrrhizae, long-pending reality, the root of kudzu vine are put in pot, it is subsequently adding 300 ~ 400 parts of water, first boils with big fire, then turn boiling with soft fire 20-30 minute, by well-done pharmaceutical filtration, obtain liquid 1 and the dregs of a decoction；

(3) dregs of a decoction and rock sugar add 200-300 part water big fire to boil, then boiling with soft fire 10-20 minute, add wrinkled giant hyssop and boil 8-15 minute, be filtrated to get liquid 2；

(4) by 2-in-1 to liquid 1 and liquid also, add honey, after stirring and evenly mixing, obtain pharmaceutical preparation.

The instructions of taking of this pharmaceutical preparation is 100mL successively, 3 times on the one.

Beneficial effects of the present invention: charred FRUCTUS CRATAEGI has stomach strengthening and digestion promoting, promoting the circulation of qi dissipates the effect of the stasis of blood, with dried orange peel with after, to abdominal distention by obvious effect；Dried orange peel energy regulating qi-flowing for eliminating phlegm, drying damp and strengthening spleen, having indigestion, lower gas can be disappeared except completely, to poor appetite, vomitting significant curative effect of having had loose bowels after rhizoma atractylodis, bark of official magnolia compatibility；Lotus nut can reduce internal heat calm the nerves, clearing away heart-fire expels the heat-evil；PORIA ALBA can invigorating the spleen again can excreting dampness, have loose bowels for what insufficiency of the spleen transporting market caused, carry inferior symptom to have significant curative effect；Wrinkled giant hyssop cure mainly dampness taste, abdominal fullness and distention, damp-warm syndrome from the beginning of, vomit, have loose bowels, the disease such as summer-heat and damp, fever with chilliness, fever with aversion to cold, chest distress；Buddha's hand is of high nutritive value, and to treatment indigestion, chest and abdomen are swollen vexed has significantly more curative effect；The dried immature fruit of citron orange can disappear long-pending by relieving stagnant Qi, scattered ruffian of reducing phlegm；Rock sugar energy bowl spares together, and stomach moistening lung, promote the eliminating of vivotoxin, it is also possible to the mouthfeel of regulating drug；Honey can strengthen the body resistance to disease, and to functions of intestines and stomach by regulating effect, gastric acid secretion can be made normal, strengthen the creeping effect of stomach.The present invention, by the mutual compatibility between medicine, makes medicine effect be not fully exerted, and the medicine concocted out by this method farthest remains the active ingredient of medicine, treatment functional dyspepsia FD is had significant effect, and instant effect, has no side effect.

Detailed description of the invention

For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that, described embodiment is a part of embodiment of the present invention rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, broadly fall into the scope of protection of the invention.

Embodiment 1 :

The preparation method of a kind of pharmaceutical preparation treating functional dyspepsia FD, comprises the following steps:

(1) 12 parts of charred FRUCTUS CRATAEGIs, 8 parts of dried orange peels, 6 portions of ginger are processed the bark of official magnolia, 8 parts of rhizoma atractylodis, 5 parts of lotus nuts, 7 parts of PORIA ALBAs, 1.5 portions of wrinkled giant hyssops, 6 portions of Buddha's hands, 15 portions of Radix Glycyrrhizaes, 8 parts fry after long-pending real, 12 parts of root of kudzu vine clear water clean, then steep 1-2 hour with warm water；

(2) by the charred FRUCTUS CRATAEGI in step (1), dried orange peel, ginger processs the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, Buddha's hand, Radix Glycyrrhizae, stir-fry is amassed in fact, the root of kudzu vine is put in pot, it is subsequently adding 300 ~ 400 parts of water, first boil with big fire, then boiling with soft fire 20-30 minute is turned, by well-done pharmaceutical filtration, obtain liquid 1 and the dregs of a decoction；

(3) dregs of a decoction and 18 portions of rock sugar are added 200-300 part water big fire and boil, then boiling with soft fire 10-20 minute, add wrinkled giant hyssop and boil 8-15 minute, be filtrated to get liquid 2；

(4) by 2-in-1 to liquid 1 and liquid also, add 28 parts of honey, after stirring and evenly mixing, obtain pharmaceutical preparation.

Typical case: Wei XX, female, 60 years old, upper abdomen distending pain, poor appetite, One's spirits are drooping, after taking this preparation 1 day, symptom alleviates, after taking 5 days, abdominal distension disappear, appetite increases, and mental status is good.

Embodiment 2 :

The preparation method of a kind of pharmaceutical preparation treating functional dyspepsia FD, comprises the following steps:

(1) 10 parts of charred FRUCTUS CRATAEGIs, 15 parts of dried orange peels, 8 portions of ginger are processed the bark of official magnolia, 3 parts of rhizoma atractylodis, 3 parts of lotus nuts, 3 parts of PORIA ALBAs, 0.5 portion of wrinkled giant hyssop, 8 portions of Buddha's hands, 10 portions of Radix Glycyrrhizaes, 5 parts fry after long-pending real, 8 parts of root of kudzu vine clear water clean, then steep 1-2 hour with warm water；

(2) by the charred FRUCTUS CRATAEGI in step (1), dried orange peel, ginger processs the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, Buddha's hand, Radix Glycyrrhizae, stir-fry is amassed in fact, the root of kudzu vine is put in pot, it is subsequently adding 300 ~ 400 parts of water, first boil with big fire, then boiling with soft fire 20-30 minute is turned, by well-done pharmaceutical filtration, obtain liquid 1 and the dregs of a decoction；

(3) dregs of a decoction and 20 portions of rock sugar are added 200-300 part water big fire and boil, then boiling with soft fire 10-20 minute, add wrinkled giant hyssop and boil 8-15 minute, be filtrated to get liquid 2；

(4) by 2-in-1 to liquid 1 and liquid also, add 25 parts of honey, after stirring and evenly mixing, obtain pharmaceutical preparation.

Typical case: Lee XX, female, 40 years old, belly distending pain, heartburn belch, with vomiting, after taking this preparation 2 days, transference cure.

Embodiment 3 :

The preparation method of a kind of pharmaceutical preparation treating functional dyspepsia FD, comprises the following steps:

(1) 12 parts of charred FRUCTUS CRATAEGIs, 10 parts of dried orange peels, 10 portions of ginger are processed the bark of official magnolia, 6 parts of rhizoma atractylodis, 6 parts of lotus nuts, 8 parts of PORIA ALBAs, 1 portion of wrinkled giant hyssop, 4 portions of Buddha's hands, 16 portions of Radix Glycyrrhizaes, 8 parts fry after long-pending real, 5 parts of root of kudzu vine clear water clean, then steep 1-2 hour with warm water；

(2) by the charred FRUCTUS CRATAEGI in step (1), dried orange peel, ginger processs the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, Buddha's hand, Radix Glycyrrhizae, stir-fry is amassed in fact, the root of kudzu vine is put in pot, it is subsequently adding 300 ~ 400 parts of water, first boil with big fire, then boiling with soft fire 20-30 minute is turned, by well-done pharmaceutical filtration, obtain liquid 1 and the dregs of a decoction；

(3) dregs of a decoction and 15 portions of rock sugar are added 200-300 part water big fire and boil, then boiling with soft fire 10-20 minute, add wrinkled giant hyssop and boil 8-15 minute, be filtrated to get liquid 2；

(4) by 2-in-1 to liquid 1 and liquid also, add 20 parts of honey, after stirring and evenly mixing, obtain pharmaceutical preparation.

Typical case: Wu X, man 28 years old, distended tummy is with pain, belch, poor appetite, and after taking this pharmaceutical preparation 1 day, symptom alleviates, and abdominal pain sense disappears, and after taking 3 days, without abdominal distension sense, appetite strengthens.

Embodiment 4 :

The preparation method of a kind of pharmaceutical preparation treating functional dyspepsia FD, comprises the following steps:

(1) 15 parts of charred FRUCTUS CRATAEGIs, 5 parts of dried orange peels, 5 portions of ginger are processed the bark of official magnolia, 9 parts of rhizoma atractylodis, 6 parts of lotus nuts, 6 parts of PORIA ALBAs, 2 portions of wrinkled giant hyssops, 8 portions of Buddha's hands, 20 portions of Radix Glycyrrhizaes, 5 parts fry after long-pending real, 15 parts of root of kudzu vine clear water clean, then steep 1-2 hour with warm water；

(2) by the charred FRUCTUS CRATAEGI in step (1), dried orange peel, ginger processs the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, Buddha's hand, Radix Glycyrrhizae, stir-fry is amassed in fact, the root of kudzu vine is put in pot, it is subsequently adding 300 ~ 400 parts of water, first boil with big fire, then boiling with soft fire 20-30 minute is turned, by well-done pharmaceutical filtration, obtain liquid 1 and the dregs of a decoction；

(3) dregs of a decoction and 16 portions of rock sugar are added 200-300 part water big fire and boil, then boiling with soft fire 10-20 minute, add wrinkled giant hyssop and boil 8-15 minute, be filtrated to get liquid 2；

(4) by 2-in-1 to liquid 1 and liquid also, add 30 parts of honey, after stirring and evenly mixing, obtain pharmaceutical preparation.

Typical case: money X, 16 years old, distended tummy, it is reluctant to take food, after taking this pharmaceutical preparation 2 days, transference cure, can normally take food.

The present invention is used for clinical treatment patients with functional dyspepsia 150 example, and cure rate reaches 82%, and have significant curative effect accounts for 6%, and patient, after taking this pill, bad reaction does not the most occur.

To sum up, the embodiment of the present invention has the advantages that the present invention passes through the mutual compatibility between medicine, medicine effect is made to be not fully exerted, the medicine concocted out by this method, farthest remain the active ingredient of medicine, to treatment functional dyspepsia FD by significant effect, and instant effect, have no side effect.

It should be noted that, in this article, the relational terms of such as first and second or the like is used merely to separate an entity or operation with another entity or operating space, and not necessarily requires or imply the relation or sequentially that there is any this reality between these entities or operation.And, term " includes ", " comprising " or its any other variant are intended to comprising of nonexcludability, so that include that the process of a series of key element, method, article or equipment not only include those key elements, but also include other key elements being not expressly set out, or also include the key element intrinsic for this process, method, article or equipment.In the case of there is no more restriction, statement " including ... " key element limited, it is not excluded that there is also other identical element in including the process of described key element, method, article or equipment.

Above example only in order to technical scheme to be described, is not intended to limit；Although the present invention being described in detail with reference to previous embodiment, it will be understood by those within the art that: the technical scheme described in foregoing embodiments still can be modified by it, or wherein portion of techniques feature is carried out equivalent；And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.

Claims (6)

1. treat dyspeptic pharmaceutical preparation for one kind, it is characterized in that, be made up of the material of following weight portion: hawthorn 10-15 part, dried orange peel 5-15 part, bark of official magnolia 5-10 part, rhizoma atractylodis 3-9 part, lotus nut 3-6 part, PORIA ALBA 3-8 part, wrinkled giant hyssop 0.5-2 part, Buddha's hand 4-8 part, Radix Glycyrrhizae 10-20 part, long-pending real 5-8 part, root of kudzu vine 5-15 part, honey 20-30 part, rock sugar 15-20 part.

2. the dyspeptic pharmaceutical preparation for the treatment of as claimed in claim 1, it is characterized in that, be made up of the material of following weight portion: hawthorn 12 parts, dried orange peel 8 parts, the bark of official magnolia 6 parts, rhizoma atractylodis 8 parts, lotus nut 5 parts, PORIA ALBA 7 parts, wrinkled giant hyssop 1.5 parts, Buddha's hand 6 parts, 15 parts of Radix Glycyrrhizae, long-pending reality 8 parts, the root of kudzu vine 12 parts, honey 28 parts, 18 parts of rock sugar.

3. the dyspeptic pharmaceutical preparation for the treatment of as claimed in claim 2, it is characterised in that described hawthorn is charred FRUCTUS CRATAEGI.

4. the dyspeptic pharmaceutical preparation for the treatment of as claimed in claim 3, it is characterised in that the described bark of official magnolia is that ginger processs the bark of official magnolia.

5. the dyspeptic pharmaceutical preparation for the treatment of as claimed in claim 4, it is characterised in that the described dried immature fruit of citron orange is for frying the dried immature fruit of citron orange.

6. the preparation method treating dyspeptic pharmaceutical preparation as described in claim 1 ~ 5 is arbitrary, it is characterised in that comprise the following steps:

(1) after hawthorn, dried orange peel, the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, wrinkled giant hyssop, Buddha's hand, Radix Glycyrrhizae, long-pending reality, the root of kudzu vine being cleaned with clear water, then steep 1-2 hour with warm water；

(2) hawthorn in step (1), dried orange peel, the bark of official magnolia, rhizoma atractylodis, lotus nut, PORIA ALBA, Buddha's hand, Radix Glycyrrhizae, long-pending reality, the root of kudzu vine are put in pot, it is subsequently adding 300 ~ 400 parts of water, first boils with big fire, then turn boiling with soft fire 20-30 minute, well-done Chinese medicine is filtered, obtains liquid 1 and the dregs of a decoction；

(3) dregs of a decoction and rock sugar add 200-300 part water big fire to boil, then boiling with soft fire 10-20 minute, add wrinkled giant hyssop and boil 8-15 minute, be filtrated to get liquid 2；

(4) by 2-in-1 to liquid 1 and liquid also, add honey, after stirring and evenly mixing, obtain pharmaceutical preparation.