CN105902605A - Composition for treating Chinese bee sacbrood and preparation method thereof - Google Patents

Composition for treating Chinese bee sacbrood and preparation method thereof Download PDF

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Publication number
CN105902605A
CN105902605A CN201610441480.4A CN201610441480A CN105902605A CN 105902605 A CN105902605 A CN 105902605A CN 201610441480 A CN201610441480 A CN 201610441480A CN 105902605 A CN105902605 A CN 105902605A
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Prior art keywords
parts
radix glycyrrhizae
flos lonicerae
white sugar
sacbrood
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CN201610441480.4A
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璧电孩
赵红
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Guizhou Wuchuan Mayang River Apiculture Development Co Ltd
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Guizhou Wuchuan Mayang River Apiculture Development Co Ltd
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Priority to CN201610441480.4A priority Critical patent/CN105902605A/en
Publication of CN105902605A publication Critical patent/CN105902605A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a composition for treating Chinese bee sacbrood and a preparation method thereof and belongs to the technical field of animal epidemic prevention and treatment. The composition is prepared from, by weight, 20-50 parts of Japanese flowering fern rhizomes, 20-50 parts of flos lonicerae, 5-10 parts of radix glycyrrhizae and 400-500 parts of white sugar. The preparation method comprises the following steps that the Japanese flowering fern rhizomes, flos lonicerae and radix glycyrrhizae are put in a container according to respective parts by weight; after 400-500 parts by weight of water is added, the mixture is boiled with a strong fire and then decocted for 15-20 min with a slow fire; the decoction passes through a 10-20 mesh screen, filter residues are discarded, 400-500 parts of white sugar is added into filter liquor and boiled into syrup, and the composition for treating Chinese bee sacbrood can be obtained. The Japanese flowering fern rhizomes, flos lonicerae and radix glycyrrhizae are compounded and then mixed with white sugar which serves as the main material, the prepared composition is sweet in smell and good in palatability, pathogens of sacbrood can be effectively killed, the pathogens are prevented from infecting the respiratory tract, the treatment effect of the composition is maintained, and then the purpose of healing sacbrood is achieved.

Description

A kind of compositions treating Chinese bee sacbrood and preparation method thereof
Technical field
The present invention relates to animal epidemic Prevention Technique field, be specifically related to a kind of compositions treating Chinese bee sacbrood and preparation method thereof.
Background technology
During Chinese bee sacbrood is called for short, capsule is sick, is commonly called as rotten son sick, the development of this disease serious harm China apis cerana aquaculture.Middle capsule disease is middle honeybee respiratory infection diseases, opening if infected at bee farm, aggravating one's illness in general one month, and middle capsule disease spread speed is fast, and the range of activity of middle honeybee is big, and its main infection larva makes its death of causing a disease, it is possible to breed in becoming honeybee body.Bee colony morbidity often has two types, and one is to generally occur within nearly hundred dead larvae in bee colony, and worker honeybees foraging activity is movable normal, is referred to as " chronic type ";Another kind is early spring or late fall, ill during swarm breeding, occurs large quantities of dead larvae in bee colony, and worker bee performance uneasiness, collection power is decreased obviously, and even cluster flies to escape, and is referred to as " acute ".Primary disease mortality rate is high, and Chang Chun, season in summer two are popular.
At present, for treating Western medicine such as moroxydine, virazole and the amantadine etc. of the drug main of Chinese bee sacbrood antiviral to be had class, but Western medicine likely causes the quickening variation of virus, and have the risk polluting commodity Mel, the most forbidden using in honeybee diseases is prevented and treated by National agricultural portion.Although some Chinese medicine formula is as really having certain effect to Stephania cepharatha Hayata, Rhizoma Polygoni Cuspidati, Radix Glycyrrhizae and vitamin, Radix Stephaniae Japonicae, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Radix Glycyrrhizae, Cortex Acanthopancis, Ramulus Cinnamomi etc. to the preventing and treating of Chinese bee sacbrood, but effect is unstable, and cannot cure.
Summary of the invention
The invention is intended to provide a kind of compositions treating Chinese bee sacbrood and preparation method thereof, unstable to solve Chinese medicine formula effect when treating sac brood of prior art, and the defect that cannot cure.
A kind of compositions treating Chinese bee sacbrood in this programme, described raw material includes that Rhizoma Osmundae, Flos Lonicerae, Radix Glycyrrhizae and white sugar, the parts by weight of each raw material are: the Rhizoma Osmundae of 20 ~ 50 parts, the Flos Lonicerae of 20 ~ 50 parts, the Radix Glycyrrhizae of 5 ~ 10 parts and 400 ~ 450 parts of white sugar.
As preferably, a kind of compositions treating Chinese bee sacbrood, the parts by weight of each raw material are: the Rhizoma Osmundae of 50 parts, the Flos Lonicerae of 50 parts, the Radix Glycyrrhizae of 10 parts and 450 parts of white sugar.
As preferably, a kind of compositions treating Chinese bee sacbrood, the parts by weight of each raw material are: the Rhizoma Osmundae of 20 parts, the Flos Lonicerae of 20 parts, the Radix Glycyrrhizae of 5 parts and 400 parts of white sugar.
As preferably, a kind of compositions treating Chinese bee sacbrood, the parts by weight of each raw material are: the Rhizoma Osmundae of 40 parts, the Flos Lonicerae of 40 parts, the Radix Glycyrrhizae of 10 parts and 420 parts of white sugar.
Beneficial effects of the present invention: Rhizoma Osmundae is a herb, for rhizome and the petiole residual base of Dryopteridaceae plant dryopteris crassirhizoma.Puckery, hardship, cold in nature, slightly poisonous, the diseases such as anemopyretic cold, conjunctival congestion, laryngopharynx swelling and pain, cough with copious phlegm can be treated.The prevention infectious disease such as epidemic encephalitis type B, mumps, has anthelmintic parasite killing, the effect of expelling wind and activating blood circulation.
Flos Lonicerae, has another name called Radix Ophiopogonis, is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and do not injure one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, be also apt to removing summer-heat blood poison, for various febrile diseases, such as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal effect is notable.
Radix Glycyrrhizae, another name: state is old, Herba Hedyotis cantonensis, Glycyrrhiza uralensis Fisch., sweet root.Pulse family, Glycyrrhiza perennial herb, root is sturdy with root stock, a kind of tonification Chinese herbal medicine, can eliminating fire and detoxication, ulcerative carbuncle swells and ache and medicine, alimentary toxicosis, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Mix with white sugar after compounding to Rhizoma Osmundae, Flos Lonicerae and Radix Glycyrrhizae, white sugar is as major ingredient, and Rhizoma Osmundae, Flos Lonicerae and Radix Glycyrrhizae are as adjuvant, the abnormal smells from the patient of the compositions prepared is fresh and sweet, palatability is more preferable, will not be because of because Chinese medicine ingredients be too much, and then Apis is looked for food impact containing fishy smell or bitterness, after Rhizoma Osmundae, Flos Lonicerae and Radix Glycyrrhizae are compounding, can effectively kill the pathogen of sac brood, and stop pathogen to infect in respiratory tract, keep its therapeutic effect, and then reach to cure the purpose of sac brood.
A kind of preparation method of the compositions of Chinese bee sacbrood, comprise the following steps: Rhizoma Osmundae, Flos Lonicerae and the Radix Glycyrrhizae of above-mentioned number are put into container, after adding the water that parts by weight are 400 ~ 500 parts, intense fire boils, slow fire boiling 15 ~ 20min afterwards, crosses 10 ~ 20 mesh sieves, abandons its filtering residue, in filtrate, add the white sugar of above-mentioned number, be brewed into syrup and can obtain medical treatment the compositions of Chinese bee sacbrood.
Beneficial effects of the present invention: after Rhizoma Osmundae, Flos Lonicerae and Radix Glycyrrhizae are decocted, the beneficiating ingredient in Chinese medicine is made to overflow, enter in filtrate, it is brewed into syrup again with white sugar, increases the palatability of compositions, conveniently feed, medicated diet as middle honeybee uses, middle honeybee will not repel compositions, and sac brood, through the treatment of three courses for the treatment of, can be fully recovered.
Detailed description of the invention
Below by detailed description of the invention, the present invention is further detailed explanation:
Embodiment 1: the preparation method of the compositions of a kind of Chinese bee sacbrood, comprise the following steps: the Radix Glycyrrhizae of the Rhizoma Osmundae of 50 parts, the Flos Lonicerae of 50 parts and 10 parts is put into container, after adding the water that parts by weight are 500 parts, first boil with high heat, after solution seethes with excitement, use slow fire boiling 15 ~ 20min, decoction liquor is crossed 10 ~ 20 mesh sieves, abandon its filtering residue, stay its filtrate, in filtrate, add the white sugar of 450 parts, heat while stirring, it is brewed into syrup, the compositions of the Chinese bee sacbrood that can obtain medical treatment.
Embodiment 2: the preparation method of the compositions of a kind of Chinese bee sacbrood, comprise the following steps: the Radix Glycyrrhizae of the Rhizoma Osmundae of 20 parts, the Flos Lonicerae of 20 parts and 5 parts is put into container, after adding the water that parts by weight are 400 parts, first boil with high heat, after solution seethes with excitement, use slow fire boiling 15 ~ 20min, decoction liquor is crossed 10 ~ 20 mesh sieves, abandon its filtering residue, stay its filtrate, in filtrate, add the white sugar of 400 parts, heat while stirring, it is brewed into syrup, the compositions of the Chinese bee sacbrood that can obtain medical treatment.
Embodiment 3: the preparation method of the compositions of a kind of Chinese bee sacbrood, comprise the following steps: the Radix Glycyrrhizae of the Rhizoma Osmundae of 40 parts, the Flos Lonicerae of 40 parts and 10 parts is put into container, after adding the water that parts by weight are 450 parts, first boil with high heat, after solution seethes with excitement, use slow fire boiling 15 ~ 20min, decoction liquor is crossed 10 ~ 20 mesh sieves, abandon its filtering residue, stay its filtrate, in filtrate, add the white sugar of 420 parts, heat while stirring, it is brewed into syrup, the compositions of the Chinese bee sacbrood that can obtain medical treatment.
During use, being used for feeding diseased bee colonies by compositions, every other day feed once, within 5 days, be a course for the treatment of, continue 3 courses for the treatment of, can cure Chinese bee sacbrood, cure rate is more than 95%.
Test data is set, by using embodiment 1, embodiment 2, embodiment 3 and being used alone Rhizoma Osmundae, Flos Lonicerae and Radix Glycyrrhizae as experiment contrast, one group of distilled water is set as negative control, feed diseased bee colonies, amount to 300, every other day feed once, within 5 days, be a course for the treatment of, lasting 3 course cure rate such as following tables:
Learning according to test data, the cure rate of the compositions of the present invention, more than 95%, is far above the cure rate being used alone Rhizoma Osmundae or Flos Lonicerae or Radix Glycyrrhizae, and therefore the effect of the present invention is the most notable.
Above-described is only embodiments of the invention, and in scheme, the known general knowledge such as concrete structure and characteristic too much describes at this.Should be understood that; for a person skilled in the art, on the premise of without departing from present configuration, it is also possible to make some deformation and improvement; these also should be considered as protection scope of the present invention, and these are all without affecting effect and the practical applicability that the present invention implements.The protection domain that this application claims should be as the criterion with the content of its claim, and the detailed description of the invention in description etc. records the content that may be used for explaining claim.

Claims (5)

1. the compositions treating Chinese bee sacbrood, it is characterised in that raw material includes that Rhizoma Osmundae, Flos Lonicerae, Radix Glycyrrhizae and white sugar, the parts by weight of each raw material are: the Rhizoma Osmundae of 20 ~ 50 parts, the Flos Lonicerae of 20 ~ 50 parts, the Radix Glycyrrhizae of 5 ~ 10 parts and 400 ~ 450 parts of white sugar.
The compositions for the treatment of Chinese bee sacbrood the most according to claim 1, it is characterised in that: the parts by weight of each raw material are: the Rhizoma Osmundae of 50 parts, the Flos Lonicerae of 50 parts, the Radix Glycyrrhizae of 10 parts and 450 parts of white sugar.
The compositions for the treatment of Chinese bee sacbrood the most according to claim 1, it is characterised in that: the parts by weight of each raw material are: the Rhizoma Osmundae of 20 parts, the Flos Lonicerae of 20 parts, the Radix Glycyrrhizae of 5 parts and 400 parts of white sugar.
The compositions for the treatment of Chinese bee sacbrood the most according to claim 1, it is characterised in that: the parts by weight of each raw material are: the Rhizoma Osmundae of 40 parts, the Flos Lonicerae of 40 parts, the Radix Glycyrrhizae of 10 parts and 420 parts of white sugar.
5. according to the preparation method of the compositions treating Chinese bee sacbrood described in any one of claim 1 ~ 4, it is characterized in that: comprise the following steps: Rhizoma Osmundae, Flos Lonicerae and the Radix Glycyrrhizae of above-mentioned number are put into container, after adding the water that parts by weight are 400 ~ 500 parts, intense fire boils, slow fire boiling 15 ~ 20min afterwards, crosses 10 ~ 20 mesh sieves, abandons its filtering residue, in filtrate, add the white sugar of above-mentioned number, be brewed into syrup and can obtain medical treatment the compositions of Chinese bee sacbrood.
CN201610441480.4A 2016-06-20 2016-06-20 Composition for treating Chinese bee sacbrood and preparation method thereof Withdrawn CN105902605A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106580975A (en) * 2016-12-12 2017-04-26 靳国保 Medicine for treating Chinese sacbrood bee virus
CN107596079A (en) * 2017-10-13 2018-01-19 山西恒达蕾傲生物科技有限公司 A kind of Chinese medicine preparation and its application process for preventing and treating honeybee sac brood
CN107714986A (en) * 2017-11-27 2018-02-23 安徽省甘泉养蜂专业合作社 A kind of protective agents of Chinese honeybee European foul brood and preparation method thereof
CN107737162A (en) * 2017-12-07 2018-02-27 潘显成 Treat the medicine of Chinese bee sacbrood
CN108938902A (en) * 2018-10-10 2018-12-07 道真仡佬族苗族自治县珍珍园中蜂养殖场 A kind of apis cerana epidemic prevention and control Chinese herbal medicine and preparation method thereof
CN115054628A (en) * 2022-07-15 2022-09-16 赣州市林业科学研究所 Chinese herbal medicine preparation for bees and oil-tea camellia forest bee breeding method

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CN103301208A (en) * 2013-05-28 2013-09-18 福建农林大学 Chinese herbal medicinal preparation for preventing and treating Chinese sacbrood

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CN101011469A (en) * 2007-02-05 2007-08-08 广东省昆虫研究所 Medicament for treating Chinese bee sacbrood and its preparing method
CN103301208A (en) * 2013-05-28 2013-09-18 福建农林大学 Chinese herbal medicinal preparation for preventing and treating Chinese sacbrood

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106580975A (en) * 2016-12-12 2017-04-26 靳国保 Medicine for treating Chinese sacbrood bee virus
CN107596079A (en) * 2017-10-13 2018-01-19 山西恒达蕾傲生物科技有限公司 A kind of Chinese medicine preparation and its application process for preventing and treating honeybee sac brood
CN107714986A (en) * 2017-11-27 2018-02-23 安徽省甘泉养蜂专业合作社 A kind of protective agents of Chinese honeybee European foul brood and preparation method thereof
CN107737162A (en) * 2017-12-07 2018-02-27 潘显成 Treat the medicine of Chinese bee sacbrood
CN108938902A (en) * 2018-10-10 2018-12-07 道真仡佬族苗族自治县珍珍园中蜂养殖场 A kind of apis cerana epidemic prevention and control Chinese herbal medicine and preparation method thereof
CN115054628A (en) * 2022-07-15 2022-09-16 赣州市林业科学研究所 Chinese herbal medicine preparation for bees and oil-tea camellia forest bee breeding method
CN115054628B (en) * 2022-07-15 2023-07-25 赣州市林业科学研究所 Chinese herbal medicine preparation for bees and method for raising bees in camellia oleifera forest

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