CN105891457A - Ultrasonic blood flow distribution device based on capillarity and working method thereof - Google Patents
Ultrasonic blood flow distribution device based on capillarity and working method thereof Download PDFInfo
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- CN105891457A CN105891457A CN201610390199.2A CN201610390199A CN105891457A CN 105891457 A CN105891457 A CN 105891457A CN 201610390199 A CN201610390199 A CN 201610390199A CN 105891457 A CN105891457 A CN 105891457A
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- reagent container
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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Abstract
The invention discloses an ultrasonic blood flow distribution device based on the capillarity and a working method thereof. The ultrasonic blood flow distribution device comprises a reagent vessel, a plurality of capillary guide tubes, a plurality of piezoelectric ceramic pieces and flexible clamps. The reagent vessel is cylindrical, one end of the reagent vessel is closed, and the other end of the reagent vessel is open. The capillary guide tubes are arranged on the tube wall of the reagent vessel in a distributed mode, one end of each capillary guide tube is communicated with the reagent vessel, and the other end of each capillary guide tube is communicated with the outside and sealed by the corresponding flexible clamp. The piezoelectric ceramic pieces are arranged on the outer wall of the reagent vessel and fixed to the end and the two sides of the reagent vessel in a glued mode. In the working process, tested blood in the reagent vessel is distributed into tested tubes through the capillary guide tubes based on the capillarity, and thus trace precise control can be achieved; the piezoelectric ceramic pieces are excited to generate ultrasonic vibration to increase the blood distribution speed and prevent blood coagulation and sedimentation, and meanwhile the ultrasonic vibration can assist in cleaning away blood remaining in the reagent vessel. The ultrasonic blood flow distribution device is simple in structure, convenient and controllable to operate and free of contamination.
Description
Technical field
The present invention relates to a kind of blood extraction device, particularly to a kind of ultrasonic blood shunt device based on capillarity and method of work thereof.
Background technology
Generally patient can run into blood drawing when hospital checks UP, and doctor judges patient's some disease risks that may be present by the content of each composition in inspection blood.Detection blood flow volume owing to extracting from a patient every time is limited, and how making full use of limited blood to realize the detection of various physical signs is the maximum challenge that current blood shunt device runs into.During detection blood shunt, how to ensure the blood not excess in detected test tube, do not contain other impurity and secondary pollution, not only blood shunt device is proposed strict requirements, the operational approach of medical personnel be it is also proposed requirement simultaneously.Traditional blood shunt device can not effectively ensure the uniform distribution of tested blood flow volume, cannot avoid secondary pollution completely in cleaning process simultaneously.
Summary of the invention
The technical problem to be solved is the technological deficiency existed for conventional blood part flow arrangement, propose a kind of ultrasonic blood shunt device based on capillarity and method of work thereof, blood flow volume flow-dividing control can be realized accurate, pollution-free, easy to clean simply.
The present invention solves above-mentioned technical problem by the following technical solutions:
A kind of ultrasonic blood shunt device based on capillarity, including reagent container, some capillary vessels, some piezoelectric ceramic pieces and some flexible clip；
Described reagent container is cylindric, and one end is closed, other end opening；
Described some capillary vessels are arranged on the tube wall of described reagent container, and one end turns on described reagent container, the other end and extraneous conducting；
The number of described flexible clip is identical with the number of described capillary vessel, and one_to_one corresponding is arranged on described capillary vessel, for whether controlling described capillary vessel and extraneous conducting；
Described some piezoelectric ceramic pieces are arranged on the outer wall of described reagent container.
As a kind of ultrasonic blood shunt further prioritization scheme of device based on capillarity of the present invention, described piezoelectric ceramic piece has three, the most a piece of end being arranged on described reagent container blind end, additionally two panels is correspondingly arranged on the sidewall on described reagent container both sides.
As a kind of ultrasonic blood shunt further prioritization scheme of device based on capillarity of the present invention, described piezoelectric ceramic piece uses the mode of viscose glue to be fixed on the outer wall of reagent container.
As a kind of ultrasonic blood shunt further prioritization scheme of device based on capillarity of the present invention, the outer wall of described reagent container is provided with the graduation mark for representing capacity.
The invention also discloses the method for work of a kind of ultrasonic blood shunt device based on capillarity, comprise the steps of
Step 1), when needs extraction micro blood carries out Components identification, loads reagent container by tested blood, test tubes is placed in one end of capillary vessel and extraneous conducting simultaneously, and takes off the flexible clip that capillary vessel is corresponding；
Step 2), due to capillarity, the tested blood in reagent container slowly enters in test tubes along capillary vessel；
Step 3), by applying the piezoelectric ceramic piece on signal of telecommunication excitation reagent container, make it produce supersonic vibration, in case hemostasis Flow Velocity causes tested blood long-time placement in reagent container precipitation and solidification occur slowly, accelerate tested blood simultaneously and enter the speed in test tubes by capillary vessel；
Step 4), when the volume of the tested blood that test tubes is extracted meets testing requirement, can stop shunting.
The further prioritization scheme of method of work as a kind of ultrasonic blood shunt device based on capillarity of the present invention, after stopping shunting, during the remained blood being rinsed in reagent container and capillary vessel with clear water, by applying the piezoelectric ceramic piece on signal of telecommunication excitation reagent container so that it is produce supersonic vibration to assist cleaning.
As the further prioritization scheme of method of work of a kind of ultrasonic blood shunt device based on capillarity of the present invention, use the piezoelectric ceramic piece on the signal of telecommunication excitation reagent container of sin or cos.
The present invention uses above technical scheme compared with prior art, has following technical effect that
1. utilize the blood flow that capillarity is accurately controlled in each detected test tube；
2. utilize supersonic vibration can alleviate the precipitation and solidification phenomenon occurred during blood shunt；
3. under the effect of supersonic vibration, auxiliary cleans up remained blood.
Accompanying drawing explanation
Fig. 1 is the structural representation of ultrasonic blood shunt device based on capillarity；
Fig. 2 is the fundamental diagram of ultrasonic blood shunt device based on capillarity.
In figure, 1-reagent container, 2-capillary vessel, 3-piezoelectric ceramic piece, 4-flexible clip.
Detailed description of the invention
Below in conjunction with the accompanying drawings technical scheme is described in further detail:
As it is shown in figure 1, the invention discloses a kind of ultrasonic blood shunt device based on capillarity, including reagent container, some capillary vessels, some piezoelectric ceramic pieces and some flexible clip；Described reagent container is cylindric, and one end is closed, other end opening；Described some capillary vessels are arranged on the tube wall of described reagent container, and one end turns on described reagent container, the other end and extraneous conducting；The number of described flexible clip is identical with the number of described capillary vessel, and one_to_one corresponding is arranged on described capillary vessel, for whether controlling described capillary vessel and extraneous conducting；Described some piezoelectric ceramic pieces are arranged on the outer wall of described reagent container.
The present invention gives the method to set up of a kind of piezoelectric ceramics: piezoelectric ceramic piece has three, the most a piece of end being arranged on described reagent container blind end, additionally two panels is correspondingly arranged on the sidewall on described reagent container both sides.
Piezoelectric ceramic piece can be fixed on the outer wall of reagent container in the way of using viscose glue.
For the ease of checking blood flow volume, the outer wall of reagent container is provided with the graduation mark for representing capacity..
When needs extraction micro blood carries out Components identification, tested blood is loaded in reagent container, test tubes is placed in one end of capillary vessel and extraneous conducting simultaneously, and take off the flexible clip that capillary vessel is corresponding, now due to capillarity, tested blood in reagent container will slowly enter in test tubes along capillary vessel, as shown in Figure 2.
In view of the reason that blood flow rate is slow, and tested blood long-time placement in reagent container there will be precipitation and solidification, supersonic vibration can be produced by the piezoelectric ceramic piece applying to arrange on signal of telecommunication excitation reagent container, make reagent container tube chamber will transmit continuous print ultrasound wave, tested blood can be accelerated and enter the speed in test tubes by capillary vessel, can prevent again tested blood from solidifying in reagent container and precipitating.
Capillarity is utilized can accurately to control required tested blood flow volume in test tubes.
When the capacity of the tested blood that test tubes is extracted meets testing requirement, can terminate shunting, now, the residual blood in reagent container will be imported in blood processor, but in reagent container and capillary vessel still can remaining portions residual blood, need to be rinsed with clear water.
For the remained blood in thorough scavenger reagent container, supersonic vibration auxiliary can be produced also with signal of telecommunication excitation piezoelectric ceramics and clean remained blood, to prevent the secondary pollution of reagent container.
Supersonic vibration is produced for excitation piezoelectric ceramic piece, the signal of telecommunication of sin or cos can be used as pumping signal.
Those skilled in the art of the present technique it is understood that unless otherwise defined, all terms used herein (including technical term and scientific terminology) have with the those of ordinary skill in art of the present invention be commonly understood by identical meaning.Should also be understood that those terms defined in such as general dictionary should be understood that have the meaning consistent with the meaning in the context of prior art, and unless defined as here, will not explain by idealization or the most formal implication.
Above-described detailed description of the invention; the purpose of the present invention, technical scheme and beneficial effect are further described; it is it should be understood that; the foregoing is only the detailed description of the invention of the present invention; it is not limited to the present invention; all within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. done, should be included within the scope of the present invention.
Claims (7)
1. a ultrasonic blood shunt device based on capillarity, it is characterised in that include reagent container (1), some capillary vessels (2), some piezoelectric ceramic pieces (3) and some flexible clip (4)；
Described reagent container (1) is cylindric, and one end is closed, other end opening；
Described some capillary vessels (2) are arranged on the tube wall of described reagent container (1), and one end turns on described reagent container (1), the other end and extraneous conducting；
The number of described flexible clip (4) is identical with the number of described capillary vessel (2), and one_to_one corresponding is arranged on described capillary vessel (2), whether is used for controlling described capillary vessel (2) and extraneous conducting；
Described some piezoelectric ceramic pieces (3) are arranged on the outer wall of described reagent container (1).
Ultrasonic blood shunt device based on capillarity the most according to claim 1, it is characterized in that, described piezoelectric ceramic piece (3) has three, the most a piece of end being arranged on described reagent container (1) blind end, additionally two panels is correspondingly arranged on the sidewall on described reagent container (1) both sides.
Ultrasonic blood shunt device based on capillarity the most according to claim 1, it is characterised in that described piezoelectric ceramic piece (3) uses the mode of viscose glue to be fixed on the outer wall of reagent container (1).
Ultrasonic blood shunt device based on capillarity the most according to claim 1, it is characterised in that the outer wall of described reagent container (1) is provided with the graduation mark for representing capacity.
5. method of work based on based on capillarity the ultrasonic blood shunt device described in claim 1, it is characterised in that comprise the steps of
Step 1), when needs extraction micro blood carries out Components identification, loads reagent container (1) by tested blood, test tubes is placed in one end of capillary vessel (2) and extraneous conducting simultaneously, and takes off the flexible clip (4) of capillary vessel (2) correspondence；
Step 2), due to capillarity, the tested blood in reagent container (1) slowly enters in test tubes along capillary vessel (2)；
Step 3), by applying the piezoelectric ceramic piece (3) on signal of telecommunication excitation reagent container (1), it is made to produce supersonic vibration, in case hemostasis Flow Velocity causes tested blood long-time placement in reagent container (1) precipitation and solidification occur slowly, accelerate tested blood simultaneously and enter the speed in test tubes by capillary vessel (2)；
Step 4), when the volume of the tested blood that test tubes is extracted meets testing requirement, can stop shunting.
The method of work of ultrasonic blood shunt device based on capillarity the most according to claim 5, it is characterized in that, after stopping shunting, during the remained blood being rinsed in reagent container (1) and capillary vessel (2) with clear water, by applying the piezoelectric ceramic piece (3) on signal of telecommunication excitation reagent container (1) so that it is produce supersonic vibration to assist cleaning.
7. according to the method for work of based on capillarity the ultrasonic blood shunt device described in claim 5 or 6, it is characterised in that use the piezoelectric ceramic piece (3) on signal of telecommunication excitation reagent container (1) of sin or cos.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610390199.2A CN105891457A (en) | 2016-06-03 | 2016-06-03 | Ultrasonic blood flow distribution device based on capillarity and working method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610390199.2A CN105891457A (en) | 2016-06-03 | 2016-06-03 | Ultrasonic blood flow distribution device based on capillarity and working method thereof |
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| CN105891457A true CN105891457A (en) | 2016-08-24 |
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| CN201610390199.2A Pending CN105891457A (en) | 2016-06-03 | 2016-06-03 | Ultrasonic blood flow distribution device based on capillarity and working method thereof |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314570A (en) * | 1977-11-18 | 1982-02-09 | Sarstedt W | Capillary receptacle |
| CN1902484A (en) * | 2003-11-05 | 2007-01-24 | 分离技术公司 | Disposable fluid sample collection device |
| CN201505519U (en) * | 2009-09-23 | 2010-06-16 | 魏明 | Negative pressure test tube oscillator |
| CN201842851U (en) * | 2010-09-26 | 2011-05-25 | 中国人民解放军第四军医大学 | Combined capillary tube detection device |
| WO2011120773A1 (en) * | 2010-03-31 | 2011-10-06 | Boehringer Ingelheim Microparts Gmbh | Component of a biosensor and process for production |
| CN104076157A (en) * | 2014-07-15 | 2014-10-01 | 中国科学院苏州生物医学工程技术研究所 | Oscillation device |
| CN205041404U (en) * | 2015-06-02 | 2016-02-24 | 东台市科华医疗器械有限公司 | Novel negative pressure end is blood collection container slightly |
| CN205280728U (en) * | 2015-12-31 | 2016-06-01 | 深圳市贝沃德克生物技术研究院有限公司 | Serum mark detecting system |
| CN205826663U (en) * | 2016-06-03 | 2016-12-21 | 南京航空航天大学 | A kind of ultrasonic blood shunt device based on capillarity |
-
2016
- 2016-06-03 CN CN201610390199.2A patent/CN105891457A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314570A (en) * | 1977-11-18 | 1982-02-09 | Sarstedt W | Capillary receptacle |
| CN1902484A (en) * | 2003-11-05 | 2007-01-24 | 分离技术公司 | Disposable fluid sample collection device |
| CN201505519U (en) * | 2009-09-23 | 2010-06-16 | 魏明 | Negative pressure test tube oscillator |
| WO2011120773A1 (en) * | 2010-03-31 | 2011-10-06 | Boehringer Ingelheim Microparts Gmbh | Component of a biosensor and process for production |
| US20130126022A1 (en) * | 2010-03-31 | 2013-05-23 | Boehringer Ingelheim Microparts Gmbh | Component of a biosensor and process for production |
| CN201842851U (en) * | 2010-09-26 | 2011-05-25 | 中国人民解放军第四军医大学 | Combined capillary tube detection device |
| CN104076157A (en) * | 2014-07-15 | 2014-10-01 | 中国科学院苏州生物医学工程技术研究所 | Oscillation device |
| CN205041404U (en) * | 2015-06-02 | 2016-02-24 | 东台市科华医疗器械有限公司 | Novel negative pressure end is blood collection container slightly |
| CN205280728U (en) * | 2015-12-31 | 2016-06-01 | 深圳市贝沃德克生物技术研究院有限公司 | Serum mark detecting system |
| CN205826663U (en) * | 2016-06-03 | 2016-12-21 | 南京航空航天大学 | A kind of ultrasonic blood shunt device based on capillarity |
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Application publication date: 20160824 |