CN105879138A - Extracorporeal circulation pipeline of plasma exchange device capable of switching blood separators - Google Patents
Extracorporeal circulation pipeline of plasma exchange device capable of switching blood separators Download PDFInfo
- Publication number
- CN105879138A CN105879138A CN201610401531.0A CN201610401531A CN105879138A CN 105879138 A CN105879138 A CN 105879138A CN 201610401531 A CN201610401531 A CN 201610401531A CN 105879138 A CN105879138 A CN 105879138A
- Authority
- CN
- China
- Prior art keywords
- blood
- chopper
- pipeline
- separator
- plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/342—Adding solutions to the blood, e.g. substitution solutions
- A61M1/3455—Substitution fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
- A61M1/3656—Monitoring patency or flow at connection sites; Detecting disconnections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0415—Plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses an extracorporeal circulation pipeline of a plasma exchange device capable of switching blood separators in order to solve the problem that due to blocking of blood separators, artificial liver treatment is forced to interrupt in the artificial liver treatment technical process. The extracorporeal circulation pipeline comprises a blood circulation system, a liquid supplement system, a liquid discharge system, the standby blood separator and a pipeline body, wherein the blood circulation system is composed of a blood inlet pipeline, a blood pump, the blood separators and a blood return pipeline, the liquid supplement system comprises an exchange liquid container, a liquid inlet pipeline and a liquid pump, the liquid discharge system comprises a liquid discharge pipeline, a plasma pump and a waste liquid collection container, and the standby blood separator can be supported to cut into the extracorporeal circulation pipeline immediately through the pipeline body when the blood separators in use are blocked. Thus, the problem that due to blocking of the blood separators, artificial liver treatment is forced to interrupt in the artificial liver treatment technical process is solved.
Description
Technical field
The present invention relates to a kind of medical apparatus and instruments, the apparatus for purifying blood extracorporeal circulation pipeline of a kind of changeable blood separator.
Background technology
Artificial liver technology, i.e. artificial liver blood purification technology, be that one utilizes blood purification technology temporarily to substitute liver function, makes hepatocyte be recovered regeneration, and finally saves the new medical technology of patients ' lives.In terms of technical standpoint, refer to plasmapheresis and Blood index technology, i.e. dissolve inflammation-causing substance or toxin in blood and be adsorbed to have on the solid matter of abundant surface area use from blood, remove anti-inflammatory agent and poisonous substance.Artificial liver technology is used exclusively for blood toxin expelling.Replacement therapy of blood plasma pattern therein, it uses the mode of " change-blood " that the toxin in patient plasma is drained, is i.e. that the blood plasma that patient is contained toxin changes healthy blood plasma into, the most about changes the blood plasma of whole body about 50%.
The extracorporeal circulation pipeline of existing artificial liver technology plasmapheresis device, including entering blood vessel road, blood pump, blood separator, the blood circulation of blood back pipeline composition, the waste liquid being made up of waste-solution line, blood plasma pump, waste liquid collection vessel discharges system, the displacement liquid replenishment system being made up of displacement liquid container, displacement liquid pipeline, displacement liquid pump.Its operation principle is: by outside the blood lead body of patient, through membrane plasma separation method the blood plasma of patient separated from whole blood and discard, the displacement liquids such as the FFP or the human blood protein that then supplement equivalent, the most just can remove various metabolic toxicities in the patient and virulence factor, thus reach the purpose for the treatment of.The metabolic toxicities of middle or small molecule in being possible not only to purged body due to plasma exchange, also remove the macromolecular substances such as albumen, immune complex, therefore the clearance rate of harmful substance to be got well more than hemodialysis, hemofiltration, hemoperfusion, supplement again the required material such as internal lacked albumin, thrombin simultaneously, preferably instead of some function of liver.
Artificial liver technology relies on unobstructed stable extracorporeal circulation of blood path, unobstructed circulation line is the premise for the treatment of smoothly, artificial liver technology blood flow rate is at 80 ~ 120ml/min, when blood flow is the slowest, anticoagulant injection volume not enough, the dysfunction of blood coagulation of patient: DDi numerical value easily causes transmembrane pressure (TMP) to raise higher than the situation such as normal, thus occur blood coagulation to cause separator to block in vitro, once blocking replacement therapy of blood plasma will be unable to continue, and causes this artificial liver in treatment to interrupt.
Summary of the invention
In order to solve above-mentioned technical problem, the present invention proposes the plasmapheresis device extracorporeal circulation pipeline of a kind of changeable blood separator, including entering blood vessel road, blood pump, blood separator, the blood circulation of blood back pipeline composition, the fluid infusion system being made up of displacement liquid container, water influent pipeline, liquid pump, the drainage system being made up of drain line, blood plasma pump, waste liquid collection vessel；Described blood separator includes that the outlet of blood inlet, blood, plasma inlet, plasma outlet port, the outlet of blood inlet, blood, plasma inlet, plasma outlet port are referred to as blood separator port；Described enter blood vessel road one end introduce after patient vessel, couple blood separator blood inlet through blood pump through the other end；One end of described blood back pipeline couples the outlet of blood separator blood, and the other end is by blood recovery in the patient；One end of described water influent pipeline couples displacement liquid container, and the other end couples blood back pipeline through liquid pump；One end of described drain line couples blood separator plasma outlet port, and the other end couples waste liquid collection vessel through blood plasma pump；Described blood circulation comprises two blood separators, is the first blood separator, the second blood separator；Described enter blood vessel road one end introduce after patient vessel, be divided into two-way through blood pump, road first chopper couples the blood inlet of the first blood separator, and another road the second chopper couples the blood inlet of the second blood separator；By blood recovery in the patient, the other end is divided into two-way in one end of described blood back pipeline, and a road couples the first blood separator blood outlet, and another road couples the second blood separator blood outlet；One end of described water influent pipeline couples displacement liquid container, and the other end is divided into two-way after liquid pump, and road the 3rd chopper accesses blood back pipeline, and another Lu Jing tetra-chopper accesses blood back pipeline；The termination of described drain line is made up of two-way, and road the 5th chopper connects the plasma outlet port of the first blood separator, and another Lu Jing six chopper connects the plasma outlet port of the second blood separator, and two-way couples waste liquid collection vessel after accumulating a road after blood plasma pump；Described first chopper, the 3rd chopper, the 5th chopper are first group of chopper, second chopper, the 4th chopper, the 6th chopper are second group of chopper, first group of chopper and the second chopper are coordinated signals, when first group of chopper is opened, second group of chopper closes automatically, when second group of chopper is opened, first group of chopper closes automatically.
Described blood circulation also includes the first tremulous pulse kettle, two tremulous pulse kettles of the second tremulous pulse kettle, with the first venous chambers, two venous chambers of the second venous chambers, tremulous pulse kettle, venous chambers are referred to as air catcher, described enter blood vessel road one end introduce after patient vessel, it is divided into two-way through blood pump, the first tremulous pulse kettle is accessed on one tunnel after the first chopper, first tremulous pulse kettle couples the blood inlet of the first blood separator, the second tremulous pulse kettle is accessed on another road after the second chopper, and the second tremulous pulse kettle couples the blood inlet of the second blood separator.
One end of described blood back pipeline is by blood recovery in the patient, the other end is divided into two-way, and the first venous chambers is accessed on a road, and the first venous chambers couples the blood outlet of the first blood separator, the second venous chambers is accessed on another road, and the second venous chambers couples the blood outlet of the second blood separator.
Being connected to pressure tester at the first tremulous pulse kettle, the second tremulous pulse kettle, the first venous chambers, the second venous chambers first line of a couplet, the first blood separator blood plasma import, the second blood separator blood plasma import first line of a couplet are connected to pressure tester.
It is additionally provided with injection port on blood vessel road entering.
Described pressure tester is pressure warning unit.
First chopper, the second chopper, the 3rd chopper, the 4th chopper, the 5th chopper, the 6th chopper are tubing clamp.
Described tubing clamp is single channel folder, two-way Jia Huo No. tri-folder.
The price comparison of blood separator is high, from the angle saving patient's expense, the present invention can also be when there is blocking in the first blood separator, or when blocking will occur, second blood separator is accessed in apparatus for purifying blood extracorporeal circulation pipeline, must carry out pre-punching in use due to the second blood separator and relevant pipeline, in order to solve the second blood separator and the pre-flush problem about pipeline, the present invention proposes following solution:
A kind of plasmapheresis device extracorporeal circulation pipeline of changeable blood separator, the plasmapheresis device extracorporeal circulation pipeline of changeable blood separator, including entering blood vessel road, blood pump, blood separator, the blood circulation of blood back pipeline composition, the fluid infusion system being made up of displacement liquid container, water influent pipeline, liquid pump, the drainage system being made up of drain line, blood plasma pump, waste liquid collection vessel；
Described blood separator includes that the outlet of blood inlet, blood, plasma inlet, plasma outlet port, the outlet of blood inlet, blood, plasma inlet, plasma outlet port are referred to as blood separator port；Described blood circulation comprises two blood separators, is the first blood separator, the second blood separator；Also including the first tremulous pulse kettle, two tremulous pulse kettles of the second tremulous pulse kettle, and the first venous chambers, two venous chambers of the second venous chambers in described blood circulation, tremulous pulse kettle, venous chambers are referred to as air catcher；Enter blood vessel road and comprise two-way, be first to enter blood vessel road, second enter blood vessel road；After first one end entering blood vessel road introduces patient vessel, through blood pump, the first chopper, accessing the first tremulous pulse kettle, the first tremulous pulse kettle couples the first blood separator blood outlet；Between the first chopper and blood pump first enters to be provided with pluggable coupling head on blood vessel road, second tunnel is entered the one end on blood vessel road and is entered blood vessel road by pluggable coupling head access first, the other end is through the second chopper, accessing the second tremulous pulse kettle, the second tremulous pulse kettle couples the second blood separator blood outlet；Described blood back pipeline comprises two-way, is the first blood back pipeline, the second blood back pipeline；By blood recovery in the patient, the other end accesses the first venous chambers in one end of first blood back pipeline, and the first venous chambers couples the blood outlet of the first blood separator；First blood back pipeline 4-1 is provided with pluggable coupling head, the first blood back pipeline is accessed by pluggable coupling head in one end of second blood back pipeline, the other end of the second blood back pipeline accesses the second venous chambers, and the second venous chambers couples the blood outlet of the second blood separator；Described water influent pipeline comprises two-way, is the first water influent pipeline, the second water influent pipeline；One termination displacement liquid container of the first water influent pipeline, the other end accesses the first venous chambers after liquid pump, the 3rd chopper；Being provided with pluggable coupling head in the first water influent pipeline between the 3rd chopper and liquid pump, the first water influent pipeline is accessed by pluggable coupling head in one end of the second water influent pipeline, and the other end accesses the second venous chambers after the 4th chopper；Described drain line comprises two-way, for first row liquid pipeline, second row liquid pipeline；One end of first row liquid pipeline couples waste liquid collection vessel, and the other end is followed by the plasma outlet port of the first blood separator through blood plasma pump, the 5th chopper；Being provided with pluggable coupling head on first row liquid pipeline between the 5th chopper and blood plasma pump, first row liquid pipeline is accessed by pluggable coupling head in one end of second row liquid pipeline, and the other end is followed by the plasma outlet port of the second blood separator through the 6th chopper.
Described pluggable coupling head is seal nipple, and blood vessel road is entered on the second tunnel, the second blood back pipeline, the second water influent pipeline, the termination of second row liquid pipeline are provided with puncturing head, and puncturing head thrusts seal nipple, it is achieved pipeline UNICOM.
Being connected to pressure tester at the first tremulous pulse kettle, the second tremulous pulse kettle, the first venous chambers, the second venous chambers first line of a couplet, the first blood separator blood plasma import, the second blood separator blood plasma import first line of a couplet are connected to pressure tester, and described pressure tester is pressure warning unit；It is additionally provided with injection port on blood vessel road entering.
Beneficial effect:Owing to being provided with the first blood separator, the second blood separator on plasmapheresis device extracorporeal circulation pipeline, and during in order to realize the first blood separator generation blocking, second blood separator is switched into the circuit design of extracorporeal circulation pipeline, thus solve when blood separator occurs blocking, plasmapheresis cannot continue, the difficult problem that artificial liver technology is failed.
Figure of description
Fig. 1 is present configuration schematic diagram；
Fig. 2 is the plasmapheresis device extracorporeal circulation pipeline structural representation with air catcher and the changeable blood separator of pressure tester；
Fig. 3 is the plasmapheresis device extracorporeal circulation pipeline structural representation of the changeable blood separator with pluggable coupling head；
Fig. 4 is blood separator structural representation；
nullWherein: enter blood vessel road 1、Blood pump 2、First blood separator 3-1、Second blood separator 3-2、Blood back pipeline 4、Displacement liquid container 5、Water influent pipeline 6、Liquid pump 7、Drain line 8、Blood plasma pump 9、Waste liquid collection vessel 10、Blood inlet 11-1、Blood outlet 11-2、Plasma inlet 11-3、Plasma outlet port 11-4、First chopper 12-1、Second chopper 12-2、3rd chopper 12-3、4th chopper 12-4、5th chopper 12-5、6th chopper 12-6、First tremulous pulse kettle 13-1、Second tremulous pulse kettle 13-2、First venous chambers 14-1、Second venous chambers 14-2、Pressure tester 15、Injection port 16，First enters blood vessel road 1-1、Second enters blood vessel road 1-2、First blood back pipeline 4-1、Second blood back pipeline 4-2、First water influent pipeline 6-1、Second water influent pipeline 6-2、First row liquid pipeline 8-1、Second row liquid pipeline 8-2、Pluggable coupling head 17.
Detailed description of the invention
Embodiment 1 :Such as Fig. 1, shown in 4, a kind of plasmapheresis device extracorporeal circulation pipeline of changeable blood separator, including entering blood vessel road 1, blood pump 2, blood separator 3-1, the blood circulation of blood back pipeline 4 composition, the fluid infusion system being made up of displacement liquid container 5, water influent pipeline 6, liquid pump 7, the drainage system being made up of drain line 8, blood plasma pump 9, waste liquid collection vessel 10；Described blood separator includes that blood inlet 11-1, blood export 11-2, plasma inlet 11-3, plasma outlet port 11-4, and blood inlet 11-1, blood outlet 11-2, plasma inlet 11-3, plasma outlet port 11-4 are referred to as blood separator port；Described enter blood vessel road 1 one end introduce after patient vessel, couple blood separator 3-1 blood inlet 11-1 through blood pump 2 through the other end；One end of described blood back pipeline 4 couples blood separator 3-1 blood outlet 11-2, and the other end is by blood recovery in the patient；One end of described water influent pipeline 6 couples displacement liquid container 5, and the other end couples blood back pipeline 4 through liquid pump 7；One end of described drain line 8 couples blood separator 3-1 plasma outlet port 11-4, and the other end couples waste liquid collection vessel 10 through blood plasma pump 9；Described blood circulation comprises two blood separators, is the first blood separator 3-1, the second blood separator 3-2；Described enter blood vessel road 1 one end introduce after patient vessel, it is divided into two-way through blood pump 2, one tunnel the first chopper 12-1 couples the blood inlet 11-1 of the first blood separator 3-1, another road the second chopper 12-2 and couples the blood inlet 11-1 of the second blood separator 3-2；By blood recovery in the patient, the other end is divided into two-way in one end of described blood back pipeline 4, and a road couples the first blood separator 3-1 blood outlet 11-2, and another road couples the second blood separator 3-2 blood outlet 11-2；One end of described water influent pipeline 6 couples displacement liquid container 5, and the other end is divided into two-way after liquid pump 7, and road a 3rd chopper 12-3 accesses blood back pipeline 4, and another Lu Jing tetra-chopper 12-4 accesses blood back pipeline 4；The termination of described drain line 8 is made up of two-way, one tunnel the 5th chopper 12-5 meets the plasma outlet port 11-4 of the first blood separator 3-1, another Lu Jing six chopper 12-6 meets the plasma outlet port 11-4 of the second blood separator 3-2, and two-way couples waste liquid collection vessel 10 after accumulating a road after blood plasma pump 9；Described first chopper 12-1, the 3rd chopper 12-3, the 5th chopper 12-5 are first group of chopper, second chopper 12-2, the 4th chopper 12-4, the 6th chopper 12-6 are second group of chopper, first group of chopper and the second chopper are coordinated signals, when first group of chopper is opened, second group of chopper closes automatically, when second group of chopper is opened, first group of chopper closes automatically.
Injection port 16 it is additionally provided with on blood vessel road 1 entering.
First chopper 12-1, the second chopper 12-2, the 3rd chopper 12-3, the 4th chopper 12-4, the 5th chopper 12-5, the 6th chopper 12-6 are tubing clamp.
Described tubing clamp is single channel folder, two-way Jia Huo No. tri-folder.
Embodiment 2 :As shown in Figure 2,4, a kind of plasmapheresis device extracorporeal circulation pipeline of changeable blood separator, including entering blood vessel road 1, blood pump 2, blood separator 3-1, the blood circulation of blood back pipeline 4 composition, the fluid infusion system being made up of displacement liquid container 5, water influent pipeline 6, liquid pump 7, the drainage system being made up of drain line 8, blood plasma pump 9, waste liquid collection vessel 10；Described blood separator includes that blood inlet 11-1, blood export 11-2, plasma inlet 11-3, plasma outlet port 11-4, and blood inlet 11-1, blood outlet 11-2, plasma inlet 11-3, plasma outlet port 11-4 are referred to as blood separator port；Described enter blood vessel road 1 one end introduce after patient vessel, couple blood separator 3-1 blood inlet 11-1 through blood pump 2 through the other end；One end of described blood back pipeline 4 couples blood separator 3-1 blood outlet 11-2, and the other end is by blood recovery in the patient；One end of described water influent pipeline 6 couples displacement liquid container 5, and the other end couples blood back pipeline 4 through liquid pump 7；One end of described drain line 8 couples blood separator 3-1 plasma outlet port 11-4, and the other end couples waste liquid collection vessel 10 through blood plasma pump 9；Described blood circulation comprises two blood separators, is the first blood separator 3-1, the second blood separator 3-2；Described enter blood vessel road 1 one end introduce after patient vessel, it is divided into two-way through blood pump 2, one tunnel the first chopper 12-1 couples the blood inlet 11-1 of the first blood separator 3-1, another road the second chopper 12-2 and couples the blood inlet 11-1 of the second blood separator 3-2；By blood recovery in the patient, the other end is divided into two-way in one end of described blood back pipeline 4, and a road couples the first blood separator 3-1 blood outlet 11-2, and another road couples the second blood separator 3-2 blood outlet 11-2；One end of described water influent pipeline 6 couples displacement liquid container 5, and the other end is divided into two-way after liquid pump 7, and road a 3rd chopper 12-3 accesses blood back pipeline 4, and another Lu Jing tetra-chopper 12-4 accesses blood back pipeline 4；The termination of described drain line 8 is made up of two-way, one tunnel the 5th chopper 12-5 meets the plasma outlet port 11-4 of the first blood separator 3-1, another Lu Jing six chopper 12-6 meets the plasma outlet port 11-4 of the second blood separator 3-2, and two-way couples waste liquid collection vessel 10 after accumulating a road after blood plasma pump 9；Described first chopper 12-1, the 3rd chopper 12-3, the 5th chopper 12-5 are first group of chopper, second chopper 12-2, the 4th chopper 12-4, the 6th chopper 12-6 are second group of chopper, first group of chopper and the second chopper are coordinated signals, when first group of chopper is opened, second group of chopper closes automatically, when second group of chopper is opened, first group of chopper closes automatically.
Described blood circulation also includes the first tremulous pulse kettle 13-1, second two tremulous pulse kettles of tremulous pulse kettle 13-2, with the first venous chambers 14-1, second venous chambers 14-2 two venous chambers, tremulous pulse kettle, venous chambers is referred to as air catcher, described enter blood vessel road 1 one end introduce after patient vessel, it is divided into two-way through blood pump 2, the first tremulous pulse kettle 13-1 is accessed on one tunnel after the first chopper 12-1, first tremulous pulse kettle 13-1 couples the blood inlet 11-1 of the first blood separator 3-1, the second tremulous pulse kettle 13-2 is accessed on another road after the second chopper 12-2, second tremulous pulse kettle 13-2 couples the blood inlet 11-1 of the second blood separator 3-2.
One end of described blood back pipeline 4 is by blood recovery in the patient, the other end is divided into two-way, the first venous chambers 14-1 is accessed on one road, first venous chambers 14-1 couples the blood outlet 11-2 of the first blood separator 3-1, the blood outlet 11-2 that the second venous chambers 14-2, the second venous chambers 14-2 couple the second blood separator 3-2 is accessed on another road.
Being connected to pressure tester 15 at the first tremulous pulse kettle 13-1, the second tremulous pulse kettle 13-2, the first venous chambers 14-1, the second venous chambers 14-2 first line of a couplet, the first blood separator 3-1 blood plasma import 11-3, the second blood separator 3-2 blood plasma import 11-3 first line of a couplet are connected to pressure tester 15.
Injection port 16 it is additionally provided with on blood vessel road 1 entering.
Described pressure tester 15 is pressure warning unit.
First chopper, the second chopper, the 3rd chopper, the 4th chopper, the 5th chopper, the 6th chopper are tubing clamp.
Described tubing clamp is single channel folder, two-way Jia Huo No. tri-folder.
Embodiment 3 :As shown in Figure 3,4, the price comparison of blood separator is high, from the angle saving patient's expense, the present invention can also be when there is blocking in the first blood separator 3-1, or when blocking will occur, the second blood separator 3-2 is accessed in apparatus for purifying blood extracorporeal circulation pipeline, pre-punching must be carried out due to the second blood separator 3-2 and relevant pipeline in use, in order to solve the second blood separator and the pre-flush problem about pipeline, the present invention proposes following solution:
A kind of plasmapheresis device extracorporeal circulation pipeline of changeable blood separator, including entering blood vessel road, blood pump 2, blood separator 3-1, the blood circulation of blood back pipeline 4 composition, the fluid infusion system being made up of displacement liquid container 5, water influent pipeline 6, liquid pump 7, the drainage system being made up of drain line 8, blood plasma pump 9, waste liquid collection vessel 10；Described blood separator includes that blood inlet 11-1, blood export 11-2, plasma inlet 11-3, plasma outlet port 11-4, and blood inlet 11-1, blood outlet 11-2, plasma inlet 11-3, plasma outlet port 11-4 are referred to as blood separator port；Described blood circulation comprises two blood separators, is the first blood separator 3-1, the second blood separator 3-2；Described blood circulation also includes the first tremulous pulse kettle 13-1, second two tremulous pulse kettles of tremulous pulse kettle 13-2, with the first venous chambers 14-1, two venous chambers of the second venous chambers 14-2, tremulous pulse kettle, venous chambers are referred to as air catcher, enter blood vessel road and comprise two-way, be first to enter blood vessel road 1-1, second enter blood vessel road 1-2；After first one end entering blood vessel road 1-1 introduces patient vessel, through blood pump the 2, first chopper 12-1, accessing the first tremulous pulse kettle 13-1, the first tremulous pulse kettle 13-1 couples the first blood separator 3-1 blood outlet 11-1；Between the first chopper 12-1 and blood pump 2 first enters to be provided with pluggable coupling head 17 on the 11-1 of blood vessel road, second tunnel is entered one end of blood vessel road 1-2 and is accessed first by pluggable coupling head 17 and enter blood vessel road 1-1, the other end is through the second chopper 12-2, access the second tremulous pulse kettle 13-2, the second tremulous pulse kettle 13-2 and couple the second blood separator 3-2 blood outlet 11-1；Described blood back pipeline comprises two-way, is the first blood back pipeline 4-1, the second blood back pipeline 4-2；By blood recovery in the patient, the other end accesses the blood outlet 11-2 that the first venous chambers 14-1, the first venous chambers 14-1 couple the first blood separator 3-1 in one end of first blood back pipeline 4-1；First blood back pipeline 4-1 is provided with pluggable coupling head 17, the first blood back pipeline 4-1 is accessed by pluggable coupling head 17 in one end of second blood back pipeline 4-2, the other end of the second blood back pipeline 4-2 accesses the blood outlet 11-2 that the second venous chambers 14-2, the second venous chambers 14-2 couple the second blood separator 3-2；Described water influent pipeline comprises two-way, is the first water influent pipeline 6-1, the second water influent pipeline 6-2；One termination displacement liquid container 5 of the first water influent pipeline 6-1, the other end accesses the first venous chambers 14-1 after liquid pump the 7, the 3rd chopper 12-3；Pluggable coupling head 17 it is provided with in the first water influent pipeline 6-1 between the 3rd chopper 12-3 and liquid pump 7, the first water influent pipeline 6-1 is accessed by pluggable coupling head 17 in one end of second water influent pipeline 6-2, and the other end accesses the second venous chambers 14-2 after the 4th chopper 12-4；Described drain line comprises two-way, for first row liquid pipeline 8-1, second row liquid pipeline 8-2；One end of first row liquid pipeline 8-1 couples waste liquid collection vessel 10, and the other end is followed by the plasma outlet port 11-4 of the first blood separator 3-1 through blood plasma pump the 9, the 5th chopper 12-5；It is provided with pluggable coupling head 17 on first row liquid pipeline 8-1 between the 5th chopper 12-5 and blood plasma pump 9, first row liquid pipeline 8-1 is accessed by pluggable coupling head 17 in one end of second row liquid pipeline 8-2, and the other end is followed by the plasma outlet port 11-4 of the second blood separator 3-2 through the 6th chopper 12-6.
Described pluggable coupling head 17 is seal nipple, second enters blood vessel road 1-2, the second blood back pipeline 4-2, the second water influent pipeline 6-2, the termination of second row liquid pipeline 8-2 are provided with puncturing head, and puncturing head thrusts seal nipple, it is achieved pipeline UNICOM.
It is connected to pressure tester 15 at the first tremulous pulse kettle 13-1, the second tremulous pulse kettle 13-2, the first venous chambers 14-1, the second venous chambers 14-2 first line of a couplet, first blood separator 3-1 blood plasma import 11-3, the second blood separator 3-2 blood plasma import 11-3 first line of a couplet are connected to pressure tester 15, and described pressure tester 15 is pressure warning unit；Enter first and be additionally provided with injection port on the 1-1 of blood vessel road.
Claims (10)
1. the plasmapheresis device extracorporeal circulation pipeline of a changeable blood separator, including entering blood vessel road, blood pump, blood separator, the blood circulation of blood back pipeline composition, the fluid infusion system being made up of displacement liquid container, water influent pipeline, liquid pump, the drainage system being made up of drain line, blood plasma pump, waste liquid collection vessel；
Described blood separator includes that the outlet of blood inlet, blood, plasma inlet, plasma outlet port, the outlet of blood inlet, blood, plasma inlet, plasma outlet port are referred to as blood separator port；
Described enter blood vessel road one end introduce after patient vessel, couple blood separator blood inlet through blood pump through the other end；
One end of described blood back pipeline couples the outlet of blood separator blood, and the other end is by blood recovery in the patient；
One end of described water influent pipeline couples displacement liquid container, and the other end couples blood back pipeline through liquid pump；
One end of described drain line couples blood separator plasma outlet port, and the other end couples waste liquid collection vessel through blood plasma pump；
It is characterized in that: described blood circulation comprises two blood separators, be the first blood separator, the second blood separator；
Described enter blood vessel road one end introduce after patient vessel, be divided into two-way through blood pump, road first chopper couples the blood inlet of the first blood separator, and another road the second chopper couples the blood inlet of the second blood separator；
By blood recovery in the patient, the other end is divided into two-way in one end of described blood back pipeline, and a road couples the first blood separator blood outlet, and another road couples the second blood separator blood outlet；
One end of described water influent pipeline couples displacement liquid container, and the other end is divided into two-way after liquid pump, and road the 3rd chopper accesses blood back pipeline, and another Lu Jing tetra-chopper accesses blood back pipeline；
The termination of described drain line is made up of two-way, and road the 5th chopper connects the plasma outlet port of the first blood separator, and another Lu Jing six chopper connects the plasma outlet port of the second blood separator, and two-way couples waste liquid collection vessel after accumulating a road after blood plasma pump；
Described first chopper, the 3rd chopper, the 5th chopper are first group of chopper, second chopper, the 4th chopper, the 6th chopper are second group of chopper, first group of chopper and the second chopper are coordinated signals, when first group of chopper is opened, second group of chopper closes automatically, when second group of chopper is opened, first group of chopper closes automatically.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 1, it is characterized in that: described blood circulation also includes the first tremulous pulse kettle, second two, tremulous pulse kettle tremulous pulse kettle, with the first venous chambers, second venous chambers two venous chambers, tremulous pulse kettle, venous chambers is referred to as air catcher, described enter blood vessel road one end introduce after patient vessel, it is divided into two-way through blood pump, the first tremulous pulse kettle is accessed on one tunnel after the first chopper, first tremulous pulse kettle couples the blood inlet of the first blood separator, the second tremulous pulse kettle is accessed on another road after the second chopper, second tremulous pulse kettle couples the blood inlet of the second blood separator；
One end of described blood back pipeline is by blood recovery in the patient, the other end is divided into two-way, and the first venous chambers is accessed on a road, and the first venous chambers couples the blood outlet of the first blood separator, the second venous chambers is accessed on another road, and the second venous chambers couples the blood outlet of the second blood separator.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 2, it is characterized in that: be connected to pressure tester at the first tremulous pulse kettle, the second tremulous pulse kettle, the first venous chambers, the second venous chambers first line of a couplet, the first blood separator blood plasma import, the second blood separator blood plasma import first line of a couplet are connected to pressure tester.
4. according to the plasmapheresis device extracorporeal circulation pipeline of the arbitrary described changeable blood separator of claim 1-3, it is characterised in that: it is additionally provided with injection port entering on blood vessel road.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 3, it is characterised in that: described pressure tester is pressure warning unit.
6. according to the plasmapheresis device extracorporeal circulation pipeline of the changeable blood separator described in claim 1 or 4, it is characterised in that: the first chopper, the second chopper, the 3rd chopper, the 4th chopper, the 5th chopper, the 6th chopper are tubing clamp.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 6, it is characterised in that: described tubing clamp is single channel folder, two-way Jia Huo No. tri-folder.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 1, including entering blood vessel road, blood pump, blood separator, the blood circulation of blood back pipeline composition, the fluid infusion system being made up of displacement liquid container, water influent pipeline, liquid pump, the drainage system being made up of drain line, blood plasma pump, waste liquid collection vessel；
Described blood separator includes that the outlet of blood inlet, blood, plasma inlet, plasma outlet port, the outlet of blood inlet, blood, plasma inlet, plasma outlet port are referred to as blood separator port；It is characterized in that:
Described blood circulation comprises two blood separators, is the first blood separator, the second blood separator；
Also including the first tremulous pulse kettle, two tremulous pulse kettles of the second tremulous pulse kettle, and the first venous chambers, two venous chambers of the second venous chambers in described blood circulation, tremulous pulse kettle, venous chambers are referred to as air catcher；
Enter blood vessel road and comprise two-way, be first to enter blood vessel road, second enter blood vessel road；
After first one end entering blood vessel road introduces patient vessel, through blood pump, the first chopper, accessing the first tremulous pulse kettle, the first tremulous pulse kettle couples the first blood separator blood outlet；
Between the first chopper and blood pump first enters to be provided with pluggable coupling head on blood vessel road, second tunnel is entered the one end on blood vessel road and is entered blood vessel road by pluggable coupling head access first, the other end is through the second chopper, accessing the second tremulous pulse kettle, the second tremulous pulse kettle couples the second blood separator blood outlet；
Described blood back pipeline comprises two-way, is the first blood back pipeline, the second blood back pipeline；
By blood recovery in the patient, the other end accesses the first venous chambers in one end of first blood back pipeline, and the first venous chambers couples the blood outlet of the first blood separator；
First blood back pipeline 4-1 is provided with pluggable coupling head, the first blood back pipeline is accessed by pluggable coupling head in one end of second blood back pipeline, the other end of the second blood back pipeline accesses the second venous chambers, and the second venous chambers couples the blood outlet of the second blood separator；
Described water influent pipeline comprises two-way, is the first water influent pipeline, the second water influent pipeline；
One termination displacement liquid container of the first water influent pipeline, the other end accesses the first venous chambers after liquid pump, the 3rd chopper；
Being provided with pluggable coupling head in the first water influent pipeline between the 3rd chopper and liquid pump, the first water influent pipeline is accessed by pluggable coupling head in one end of the second water influent pipeline, and the other end accesses the second venous chambers after the 4th chopper；
Described drain line comprises two-way, for first row liquid pipeline, second row liquid pipeline；
One end of first row liquid pipeline couples waste liquid collection vessel, and the other end is followed by the plasma outlet port of the first blood separator through blood plasma pump, the 5th chopper；
Being provided with pluggable coupling head on first row liquid pipeline between the 5th chopper and blood plasma pump, first row liquid pipeline is accessed by pluggable coupling head in one end of second row liquid pipeline, and the other end is followed by the plasma outlet port of the second blood separator through the 6th chopper.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 8, it is characterized in that: described pluggable coupling head is seal nipple, blood vessel road is entered on second tunnel, the second blood back pipeline, the second water influent pipeline, the termination of second row liquid pipeline are provided with puncturing head, puncturing head thrusts seal nipple, it is achieved pipeline UNICOM.
The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator the most according to claim 8, it is characterized in that: be connected to pressure tester at the first tremulous pulse kettle, the second tremulous pulse kettle, the first venous chambers, the second venous chambers first line of a couplet, first blood separator blood plasma import, the second blood separator blood plasma import first line of a couplet are connected to pressure tester, and described pressure tester is pressure warning unit；It is additionally provided with injection port on blood vessel road entering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610401531.0A CN105879138B (en) | 2016-06-11 | 2016-06-11 | The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610401531.0A CN105879138B (en) | 2016-06-11 | 2016-06-11 | The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105879138A true CN105879138A (en) | 2016-08-24 |
| CN105879138B CN105879138B (en) | 2018-12-28 |
Family
ID=56710461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610401531.0A Active CN105879138B (en) | 2016-06-11 | 2016-06-11 | The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105879138B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107583120A (en) * | 2017-09-20 | 2018-01-16 | 中南大学湘雅二医院 | A kind of plasma exchange dialysis adsorption system |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001087381A (en) * | 1999-09-21 | 2001-04-03 | Inoac Corp | New extracorporeal circulation system and artificial internal organ assisting system using the same |
| CN101041092A (en) * | 2007-04-27 | 2007-09-26 | 高光勇 | Multiple organ dysfunction and support system |
| CN201026321Y (en) * | 2007-04-28 | 2008-02-27 | 高光勇 | Artificial liver nephros support system |
| WO2012115189A1 (en) * | 2011-02-23 | 2012-08-30 | 旭化成メディカル株式会社 | Blood purification device and method for cleaning blood purification device |
| CN203329103U (en) * | 2013-06-03 | 2013-12-11 | 上海市同济医院 | Double-pump hemodialysis machine used for conducting plasma adsorption treatment |
| CN203989201U (en) * | 2014-08-15 | 2014-12-10 | 中国人民解放军第三军医大学第二附属医院 | A kind of based on Diapact CRRT machine and for the improved device of Cured by Double Filtration Plasmapheresis plasmapheresis |
| CN105107041A (en) * | 2015-06-28 | 2015-12-02 | 唐天泽 | Blood purifier and displacement method thereof |
| CN105107042A (en) * | 2015-06-28 | 2015-12-02 | 唐天泽 | Blood purifier |
-
2016
- 2016-06-11 CN CN201610401531.0A patent/CN105879138B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001087381A (en) * | 1999-09-21 | 2001-04-03 | Inoac Corp | New extracorporeal circulation system and artificial internal organ assisting system using the same |
| CN101041092A (en) * | 2007-04-27 | 2007-09-26 | 高光勇 | Multiple organ dysfunction and support system |
| CN201026321Y (en) * | 2007-04-28 | 2008-02-27 | 高光勇 | Artificial liver nephros support system |
| WO2012115189A1 (en) * | 2011-02-23 | 2012-08-30 | 旭化成メディカル株式会社 | Blood purification device and method for cleaning blood purification device |
| CN203329103U (en) * | 2013-06-03 | 2013-12-11 | 上海市同济医院 | Double-pump hemodialysis machine used for conducting plasma adsorption treatment |
| CN203989201U (en) * | 2014-08-15 | 2014-12-10 | 中国人民解放军第三军医大学第二附属医院 | A kind of based on Diapact CRRT machine and for the improved device of Cured by Double Filtration Plasmapheresis plasmapheresis |
| CN105107041A (en) * | 2015-06-28 | 2015-12-02 | 唐天泽 | Blood purifier and displacement method thereof |
| CN105107042A (en) * | 2015-06-28 | 2015-12-02 | 唐天泽 | Blood purifier |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107583120A (en) * | 2017-09-20 | 2018-01-16 | 中南大学湘雅二医院 | A kind of plasma exchange dialysis adsorption system |
| CN107583120B (en) * | 2017-09-20 | 2024-05-14 | 中南大学湘雅二医院 | Plasma exchange dialysis adsorption system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105879138B (en) | 2018-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102389594B (en) | Portable blood purifying system | |
| JP2000107283A (en) | Dialysis apparatus and washing priming method | |
| CN102753208B (en) | Dialyzer | |
| CN201026321Y (en) | Artificial liver nephros support system | |
| CN100493633C (en) | Artificial system for supporting liver and kidney | |
| CN203507201U (en) | Separating type hemodialysis absorber | |
| CN209900240U (en) | Wearable filtering type artificial kidney device | |
| CN201046965Y (en) | Universal cell processor for adding and removing low-temperature protecting agent in cell suspension | |
| CA2600238A1 (en) | Method of testing the integrity of dialysis circuit filters | |
| CN206577183U (en) | The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator | |
| JP2001245970A (en) | Priming processing method for blood circuit | |
| CN202207346U (en) | Portable blood purifying system | |
| CN105879138A (en) | Extracorporeal circulation pipeline of plasma exchange device capable of switching blood separators | |
| CN210277848U (en) | Clinical continuous blood component centrifugal separation and treatment system | |
| CN209173054U (en) | A kind of filtering device for blood dialysis with blood filtering function | |
| CN204379871U (en) | A kind of hemoperfusion cascading hemodialysis filtration system | |
| CN201026322Y (en) | Multiple organ functions support system | |
| CN106377812B (en) | A kind of plasma circulation acceleration purification system | |
| CN205460102U (en) | Hemoperfusion series connection hemodiafiltration system | |
| CN208552666U (en) | A kind of plasma exchange dialysis adsorption system | |
| CN219579541U (en) | Hemodialysis adds pipeline switch that perfusion was used | |
| JP2003507149A (en) | Astrocyte device for biological treatment of circulating fluid | |
| CN207445273U (en) | Blood purification pipeline | |
| CN201862019U (en) | Connecting bag special for matched plasma exchange, filtration and adsorption treatment | |
| CN201743989U (en) | Ultrafiltration device during extracorporeal membrane oxygenation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |