CN105878448A - Traditional Chinese medicine composition for preventing and treating hemorrhagic lernaea of crucian - Google Patents
Traditional Chinese medicine composition for preventing and treating hemorrhagic lernaea of crucian Download PDFInfo
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- CN105878448A CN105878448A CN201610319010.0A CN201610319010A CN105878448A CN 105878448 A CN105878448 A CN 105878448A CN 201610319010 A CN201610319010 A CN 201610319010A CN 105878448 A CN105878448 A CN 105878448A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention belongs to the field of fish diseases prevention and control, and particularly relates to a traditional Chinese medicine composition for preventing and treating hemorrhagic lernaea of crucian and application method thereof. The composition is prepared from the following components in parts by weight: 15-20 parts of omphalia lapidescens, 16-18 parts of gemma agrimoninae and 8-12 parts of fructus cnidii. The application method comprises the following steps: boiling gemma agrimoninae and fructus cnidii in 10 times amount of water with strong fire, decocting with slow fire for 25 minutes, filtering medicinal liquid, and pouring the medicinal liquid into a water body according to a usage of adding 500ml of medicinal liquid into every cubic meter of water after the medicinal liquid is cool; cooling medicinal residues for later use; putting the medicinal residues and omphalia lapidescens into a medicinal bag made of gauze, soaking the medicinal bag in the water body for 5 days; grinding calamine, indigo naturalis, cortex phellodendri and calcined gypsum into powder, spreading the powder into the water body once a day for totally 5 days. The composition can be used for improving the symptom of hemorrhagic lernaea of crucian, so that the death rate of suffered crucian can be reduced to10 percent or less.
Description
Technical field
The present invention relates to fish diseases prevention and control field, be specifically related to a kind of sick for preventing and treating Carassius auratus hemorrhagic anchor head Sao
Chinese medicine composition.
Background technology
The resistance against diseases of Carassius auratus is strong, but discovered in recent years Carassius auratus hemorrhagic anchor head Sao is sick, although the generation of this disease
Rate is the highest, but once catches and develop as one pleases, then can cause Carassius auratus mortality.This ill Carassius auratus of seriously ill disease is main
Showing themselves in that and swim to roam (weak), color and luster is light white, the abdominal part of fish body surface, ridge both sides (thin squamosa position)
Visible needle-like polypide is parasitic.Polypide attachment region has Semen phaseoli radiati or pisiformis congested erythema, lesions position scale pine
Moving or come off, mucus increases, and minority forms obvious ulcer.Pathogen is Cyprinus carpio anchor head Sao.
Cyprinus carpio anchor head Sao draws nutrition in head is pierced fish body, makes fish body become thin.Fish body is pierced by Cyprinus carpio anchor head Sao
Position, scale ruptures, and integumentary musculature tissue inflammation is red and swollen, tissue necrosis, and water mo(u)ld invades and grows thickly.Cyprinus carpio anchor head
Sao is exposed at the part outside fish body surface, often has vorticella and algal fungi parasitic, and outward appearance is as the Lycoperdon polymorphum Vitt of a branch of bundle
Cotton-wool.When fish body infects anchor head Sao in a large number, as draping over one's shoulders straw rain cape, therefore claim " straw rain cape is sick ".This disease is to fingerling
Harm maximum, one 6~the fingerling of 9 centimeter length, there are 3~5 Cyprinus carpio anchor head Sao parasitic, just can cause death.
Popular the most serious with autumn.
Method sick for tradition preventing and treating Carassius auratus hemorrhagic anchor head Sao has: (1) cleans up the pond sterilization with quick lime, can kill
Anchor head Sao larva in water.(2) fingerling is before putting the pool, and the potassium permanganate with 1/100000~1/50000 is molten
Immersion washes fish body 1.5~2 hours, can kill whole larva and part adult.(3) (Nidus Vespae must be killed with spider worm
Bacillus cereus B-91), every cubic metre of water body medication 0.06ml, splashed every 7 days 1 time.(3) 90% crystal is used
Metrifonate full pool spilling head, every cubic metre of water body medication 0.7 gram, splashed every 7 days 1 time, splash continuously 3 times.
The most several traditional methods about 80%, still have 20% to cure rate sick for Carassius auratus hemorrhagic anchor head Sao
Sick fish can be because this be sick and dead.
Summary of the invention
It is an object of the invention to provide a kind of for preventing and treating the sick Chinese medicine composition of Carassius auratus hemorrhagic anchor head Sao, should
Within compositions can make the mortality rate of ill Carassius auratus drop to 10%.
For reaching above-mentioned purpose, the base case of the present invention is: it is sick that one is used for preventing and treating Carassius auratus hemorrhagic anchor head Sao
Chinese medicine composition, it is characterised in that in parts by weight, including Omphalia 15-20 part, Bud of hairyvein agrimony 16-18
Part, Fructus Cnidii 8-12 part.
Omphalia is the sclerotium of Polyporaceae plant Omphalia lapidescens, and main component is that a kind of protease claims Omphalin, content
About 3%, for expelling tenia effective ingredient, heat spent.Omphalin acts on the strongest in pH8 solution, acid molten
In liquid invalid, 0.06 microgram i.e. has decomposing protein effect in 10 milliliters of alkalescence (pH8) solution;Main
Control removing food stagnancy, parasite killing.
Bud of hairyvein agrimony contains agrimophol, can kill and wash worm and cysticercosis, have lasting excitation to ascaris suum;To vagina
Infusorian, schistosomicide, plasmodium etc., also have inhibitory or killing effect.
Fructus Cnidii containing pinene, isovaleric acid borneol acetate, osthole, Columbianetin (+)-Columbianetin., bergapton,
Osthole, isopimpinellin etc.;External removing dampness and killing parasites, for various eczema, tinea of itching, pudendal pruritus.
The program have the beneficial effect that one is adult and the larva that can kill the Cyprinus carpio anchor head Sao in water body, reduce
The sickness rate of Carassius auratus, alleviates disease, reduces the mortality rate of ill Carassius auratus;Two is to Carassius auratus nonhazardous effect.
Further, Calamina 6-9 part, Indigo Naturalis 9-13 part, Cortex Phellodendri 6-9 part, Gypsum Fibrosum Preparatum 4-7 part are also included.
Calamina is used for ulcer being unable to heal, skin eczema;Can removing toxic substances and promoting granulation sore, again can removing dampness antipruritic.Indigo Naturalis tool is clear
Thermal detoxification, blood cooling and ecchymoses removing, pathogenic fire purging arresting convulsion etc. acts on.Cortex Phellodendri cures mainly aphtha of the mouth and tongue, sore swollen toxin.Gypsum Fibrosum Preparatum has
There is the effect of convergence and granulation promoting, have good therapeutic effect for sore.Calamina and Indigo Naturalis, Cortex Phellodendri, Calx
Cream is combined, and can be used for treating ulcer being unable to heal, and pus is dripping.
A kind of application process for preventing and treating Chinese medicine composition sick for Carassius auratus hemorrhagic anchor head Sao, including following step
Rapid:
(1) adding the water of 10 times in crane wheatgrass and Fructus Cnidii, big fire is boiled, and slow fire boils 25min, mistake
Filter medicinal liquid, after medicinal liquid cools down, adds the consumption of 500ml medicinal liquid, medicinal liquid is splashed into water body according to every cube of water;
Medicinal residues cooling is standby;
(2) medicinal residues cooled down in step (1) are put in the medicated bag that gauze is made together with described Omphalia,
Medicated bag is immersed in water body, soak 5 days in water body;
(3) Calamina, Indigo Naturalis, Cortex Phellodendri and Gypsum Fibrosum Preparatum are ground into powder, after mix homogeneously, powder are splashed
Enter water body;Once a day, continuous 5 days.
The medicinal liquid of crane wheatgrass and Fructus Cnidii all has killing effect to adult and the larva of Cyprinus carpio anchor head Sao;Omphalin heats
Losing efficacy, so Omphalia not being decocted, being only immersed in together with Omphalia in water body with the medicinal residues of crane wheatgrass and Fructus Cnidii,
The sustained release efficacy of a drug;The mixed-powder of Calamina, Indigo Naturalis, Cortex Phellodendri and Gypsum Fibrosum Preparatum falls at Carassius auratus body surface, to Carassius auratus
The healing of wound has significant effect.
Detailed description of the invention
Below by detailed description of the invention, the present invention is further detailed explanation:
6 groups of experimental design, often group has Carassius auratus 30 tail, and it is sick that all Carassius auratuss all suffer from hemorrhagic anchor head Sao.Respectively
Group is different except drug treating, and remaining condition is the most consistent.This experiment carries out 10 days.
First group of blank group: do not do any drug treating.
Second group of matched group: must kill (bacillus alvei B-91) with spider worm, every cubic metre of water body medication 0.06ml,
Splashed every 7 days 1 time.
3rd group of experiment A group: take Bud of hairyvein agrimony 16 parts, Fructus Cnidii 12 parts, add in 280 parts of water, big fire
Boiling, slow fire boils 25min, filtering liquid medicine, after medicinal liquid cools down, adds 500ml medicinal liquid according to every cube of water
Consumption, medicinal liquid is splashed into water body;After medicinal residues cooling, put into, together with 15 parts of Omphalias, the medicine that gauze is made
In Dai, medicated bag is immersed in water body, pull out after soaking 5 days in water body, abandon.
4th group of experiment B group: taking Bud of hairyvein agrimony 18 parts, Fructus Cnidii 8 parts, add in 260 parts of water, big fire is boiled
Boiling, slow fire boils 25min, filtering liquid medicine, after medicinal liquid cools down, adds 500ml medicinal liquid according to every cube of water
Consumption, splashes into water body by medicinal liquid;After medicinal residues cooling, put into, together with 20 parts of Omphalias, the medicated bag that gauze is made
In, medicated bag is immersed in water body, pull out after soaking 5 days in water body, abandon.
5th group of experiment C group: taking Bud of hairyvein agrimony 17 parts, Fructus Cnidii 10 parts, add in 270 parts of water, big fire is boiled
Boiling, slow fire boils 25min, filtering liquid medicine, after medicinal liquid cools down, adds 500ml medicinal liquid according to every cube of water
Consumption, splashes into water body by medicinal liquid;After medicinal residues cooling, put into, together with 18 parts of Omphalias, the medicated bag that gauze is made
In, medicated bag is immersed in water body, soak 5 days in water body.Take Calamina 6 parts, Indigo Naturalis 13 parts, Cortex Phellodendri
6 parts, Gypsum Fibrosum Preparatum 7 parts, it is ground into powder, after mix homogeneously, powder is splashed into water body;Once a day, even
Continuous 5 days.Pull medicated bag out after 5 days, abandon.
6th group of experiment D group: take Bud of hairyvein agrimony 18 parts, Fructus Cnidii 11 parts, add in 290 parts of water, big fire
Boiling, slow fire boils 25min, filtering liquid medicine, after medicinal liquid cools down, adds 500ml medicinal liquid according to every cube of water
Consumption, medicinal liquid is splashed into water body;After medicinal residues cooling, put into, together with 16 parts of Omphalias, the medicine that gauze is made
In Dai, medicated bag is immersed in water body, soak 5 days in water body.Take Calamina 9 parts, Indigo Naturalis 9 parts, Cortex Phellodendri
9 parts, Gypsum Fibrosum Preparatum 4 parts, it is ground into powder, after mix homogeneously, powder is splashed into water body;Once a day, even
Continuous 5 days.Pull medicated bag out after 5 days, abandon.
Experimental result is as follows:
Result is added up:
Blank group: dead 29 tail, other 1 shape of tail state is very poor, tends to disease and dies;Cure rate 0, improvement rate 0,
Mortality rate 96.7%.
Matched group: cure rate 26.7%, improvement rate 30.0%, mortality rate 23.3%.
Experiment A group: cure rate 40.0%, improvement rate 46.7%, mortality rate 6.7%.
Experiment B group: cure rate 53.3%, improvement rate 36.7%, mortality rate 3.3%.
Experiment C group: cure rate 66.7%, improvement rate 33.3%, mortality rate 0.
Experiment D group: cure rate 60.0%, improvement rate 40.0%, mortality rate 0.
Interpretation of result: experiment A group and B group are to have employed the base case of the present invention, experiment C group and D group
Being the preferred version of the present aspect used, this cure rate of three groups is all remarkably higher than and uses the right of conventional solution
According to group, mortality rate is substantially less than matched group, within using the mortality rate of the experimental group of the present invention to be reduced to 10%,
As can be seen here, the present invention compared to existing technology, has prominent substantive distinguishing features and significantly progress.
Above-described is only embodiments of the invention, and in scheme, the known general knowledge such as using method and characteristic is at this
Too much describe.It should be pointed out that, for a person skilled in the art, in the premise without departing from the present invention
Under, it is also possible to making some improvement, these also should be considered as protection scope of the present invention, and these are all without impact
The effect of present invention enforcement and practical applicability.The protection domain that this application claims should be with its claim
Content is as the criterion, and the detailed description of the invention in description etc. records the content that may be used for explaining claim.
Claims (3)
1. one kind is used for preventing and treating the sick Chinese medicine composition of Carassius auratus hemorrhagic anchor head Sao, it is characterised in that: according to weight
Number meter, including Omphalia 15-20 part, Bud of hairyvein agrimony 16-18 part, Fructus Cnidii 8-12 part.
It is the most according to claim 1 a kind of for preventing and treating the sick Chinese medicine composition of Carassius auratus hemorrhagic anchor head Sao,
It is characterized in that: also include Calamina 6-9 part, Indigo Naturalis 9-13 part, Cortex Phellodendri 6-9 part, Gypsum Fibrosum Preparatum 4-7 part.
The most according to claim 2 a kind of for preventing and treating Chinese medicine composition sick for Carassius auratus hemorrhagic anchor head Sao
Application process, it is characterised in that: comprise the following steps:
(1) adding the water of 10 times in crane wheatgrass and Fructus Cnidii, big fire is boiled, and slow fire boils 25min, mistake
Filter medicinal liquid, after medicinal liquid cools down, adds the consumption of 500ml medicinal liquid, medicinal liquid is splashed into water body according to every cube of water;
Medicinal residues cooling is standby;
(2) medicinal residues cooled down in step (1) are put in the medicated bag that gauze is made together with described Omphalia,
Medicated bag is immersed in water body, soak 5 days in water body;
(3) Calamina, Indigo Naturalis, Cortex Phellodendri and Gypsum Fibrosum Preparatum are ground into powder, after mix homogeneously, powder are splashed into water
Body;Once a day, continuous 5 days.
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CN201610319010.0A CN105878448A (en) | 2016-05-13 | 2016-05-13 | Traditional Chinese medicine composition for preventing and treating hemorrhagic lernaea of crucian |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107853220A (en) * | 2017-10-27 | 2018-03-30 | 王小艳 | A kind of young crucian hemorrhagic anchor head Sao diseases bring up treatment liquid |
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2016
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107853220A (en) * | 2017-10-27 | 2018-03-30 | 王小艳 | A kind of young crucian hemorrhagic anchor head Sao diseases bring up treatment liquid |
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Application publication date: 20160824 |