CN105878132A - Magnolia-flower-containing traditional Chinese medicine composition for whitening cosmetics - Google Patents
Magnolia-flower-containing traditional Chinese medicine composition for whitening cosmetics Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention discloses a magnolia-flower-containing traditional Chinese medicine composition for whitening cosmetics. The composition is prepared from, by weight, 1-5 parts of cinnamon, 15-25 parts of magnolia flowers, 9-16 parts of camellia flowers, 6-9 parts of tremella, 2-5 parts of platycodon grandiflorum and 5-10 parts of dendrobe. According to the composition, the whitening effect of the composition is improved through the synergetic enhancement effect among the raw materials, the medicine effect is mild, the composition is combined by pure natural plant extracts, the side effect is small, the adaptability is wide, and cost is low.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae.
Background technology
China, from ancient times with Bai Weimei, as the saying goes " a white screening hundred is ugly ", and whitening skin is to pursue lifetime of many Mies.Recently as expanding economy and growth in the living standard, people increasingly pay attention to the natural whitening of skin, this is just for suppression the black pigment of skin synthesis, and then the various American and Japanese firms reaching skin whitening effects provide wide application prospect, the demand making this kind of cosmetics is lasting ascendant trend.
In normal state, the color of human skin depends on melanic content and distribution, so the core content of lightening mechanism suppresses melanic formation exactly and accelerates melanic decomposition.The physiological process that melanin is formed and discharges is summarised as substantially: melanocyte produces melanin；Melanin granule is shifted to horn cell by melanocyte dendritic processes；The melanin granule of angle of shift cell plastid goes upward to horny layer with epidermis cell, and comes off along with horny layer and drain.
In recent years, the whitening agent used in cosmetics mainly has the compounds such as hydroquinone (hydroquinone), L-ascorbic acid (vitamin C), kojic acid, superoxide dismutase (SOD) and arbutin.But these whitening agents also exist many defects, zest such as hydroquinone is the biggest, vitamin C and SOD are highly unstable, kojic acid also has certain zest and property easy to change, arbutin effect is single and poor effect, the permeability adding active matter is undesirable, the effect making these whitening products is poor, and these substantial amounts of whitening agents remain in zest and the anaphylaxis that can cause again skin on skin, consumer's effect demand to whitening product can not be met, so exploitation has good safety, stability, inhibition is obvious, the natural whiting agent that cost performance is good, become one of main direction of studying of current medicine and cosmetic industry, there is extraordinary development prospect.
Summary of the invention
It is an object of the invention to overcome the deficiency that whitening effect is poor, side effect is big in the presence of prior art, it is provided that a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae.Said composition, by the chemiluminescence between raw material, adds the whitening effect of compositions, and drug effect is gentle, pure natural plant extract combines, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, said composition is to be prepared from by the raw material of following weight: Cortex Cinnamomi 1-5 part, Flos Magnoliae 15-25 part, Flos Camelliae Japonicae 9-16 part, Tremella 6-9 part, Radix Platycodonis 2-5 part, Herba Dendrobii 5-10 part.
Above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, wherein said Cortex Cinnamomi, sweet in the mouth, pungent；Property heat；Return kidney, spleen, the heart, Liver Channel；There is complement sun, warming the spleen and stomach, removing accumulated cold, effect of promoting blood circulation；Being mainly used in treating decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is floating more, heat in the upper and cold in the lower.
Wherein said Flos Magnoliae, acrid in the mouth, warm in nature；Attach to the lung and stomach meridians；There is cold-dispelling, effect of clearing the nasal passage；It is mainly used in treating headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.
Wherein said Flos Camelliae Japonicae, acrid in the mouth, hardship；Cold in nature；Return liver, lung meridian；There is cooling blood for hemostasis, dissipating blood stasis, effect that repercussive is swollen；It is mainly used in treatment to spit blood, epistaxis, hemoptysis, has blood in stool, hemorrhoidal bleeding, red dysentery, stranguria with blood, metrorrhagia, leukorrhagia, scald, injury from falling down.
Wherein said Tremella is sweet in the mouth, light；Property flat；Attach to the lung and stomach meridians；There is effect of nourishing YIN and moistening the lung；It is mainly used in treating malnutrition, sick puerperal asthenia, hypertension, sclerosis of blood vessels, retinal hemorrhage, kidney nephritis, lung-heat impairment of body fluid, cough caused by dryness without expectorant, cough with blood-flecked phlegm.
Wherein said Radix Platycodonis, bitter in the mouth, pungent；Property flat；Return lung meridian；There is lung qi dispersing, sore-throat relieving, eliminate the phlegm, effect of evacuation of pus；It is mainly used in treating cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Wherein said Herba Dendrobii, sweet in the mouth；Cold nature；Return stomach, kidney channel；There is nourishing the stomach to promote the production of body fluid, effect of YIN nourishing heat extraction；Being mainly used in treating Tianjin wound yearningly, lack of appetite constipation, deficiency-heat is not moved back, and mesh is the most dim-sighted.
Above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, it is preferred that said composition is to be prepared from by the raw material of following weight: Cortex Cinnamomi 2-3 part, Flos Magnoliae 18-23 part, Flos Camelliae Japonicae 10-14 part, Tremella 8-9 part, Radix Platycodonis 2-3 part, Herba Dendrobii 8-10 part；It is further preferred that said composition is to be prepared from by the raw material of following weight: Cortex Cinnamomi 3 parts, Flos Magnoliae 18 parts, Flos Camelliae Japonicae 12 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, Herba Dendrobii 9 parts.Preferably can make the synergistic function maximum of compositions by above-mentioned, whitening effect reaches optimal, and side effect is minimum.
Above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, in addition to above-mentioned necessary raw material, also can add auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water etc. according to actual needs.
Above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, can make cosmetics with conventional base material by arbitrary proportion, and State of cosmetics can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, said composition is made up of the natural material of multiple gentleness, and with Flos Magnoliae as monarch drug, Flos Camelliae Japonicae is ministerial drug, Tremella, Herba Dendrobii are adjuvant drug, Cortex Cinnamomi, Radix Platycodonis, for making medicine, make active component different in each raw material form synergistic function, can effectively suppress the formation of intracellular melanin thus reach quick whitening and continue the effect of whitening, whitening effect is more preferable, and drug effect is gentle, have no side effect, be suitable for all kinds of skin quality.
Further, the invention provides the preparation method of a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, its concrete preparation process is as follows:
1, pulverize after Cortex Cinnamomi, Flos Magnoliae, Flos Camelliae Japonicae, Tremella, Radix Platycodonis, Herba Dendrobii being separately dried, extract and concentrate, obtain Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, the Cortex Cinnamomi extracting solution of step 1 gained, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract are carried out maturation process respectively, carry out after cooling filtering, purifying to obtain each raw material essence, by each raw material essence mix homogeneously, and again carry out filtering, purifying, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae.
The preparation method of above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, wherein to Cortex Cinnamomi in step 1, Flos Magnoliae, Flos Camelliae Japonicae, Tremella, Radix Platycodonis, the extraction of Herba Dendrobii, method for concentration are conventional plant extract, method for concentration, the active ingredient of the whitening in plant can be separated, and increase activity component concentration, improve whitening effect.
The preparation method of above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, wherein step 2 carries out maturation process respectively to Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract, i.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in plant, reduce side effect, improve the adaptability to different skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin.
Wherein, in described curing process, the cooking conditions to each raw material is different, can be under farthest ensuring a suppression of the reactive conditions that melanin is formed, destroy the easy allergin in plant, reduce side effect, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve the absorption efficiency of skin, its temperature, pressure and time specifically chosen as follows:
| Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
| Cortex Cinnamomi | 75-80 | 0.1-0.2 | 3-4 |
| Flos Magnoliae | 65-70 | 0.1-0.2 | 0.5-1 |
| Flos Camelliae Japonicae | 65-70 | 0.1-0.2 | 0.5-1 |
| Tremella | 80-85 | 0.1-0.2 | 1-2 |
| Radix Platycodonis | 70-75 | 0.1-0.2 | 2-3 |
| Herba Dendrobii | 65-70 | 0.1-0.2 | 1-2 |
The preparation method of above-mentioned a kind of Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, by to the ripening at different conditions of different material extracting solution, easy allergin in raw material extracting solution is inactivated or decomposes, and the suppression melanin retaining energy Synergistic forms and promotes the active substance that melanin decomposes, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only reduce the allergy probability of Chinese medicine composition, improve adaptability, can also improve the absorption efficiency of skin, whitening effect is more preferable.
Compared with prior art, beneficial effects of the present invention:
1, the present composition is by the synergistic function of active component different in each raw material, excites the activity that melanin can be suppressed to form and promote the active substance that melanin decomposes therein greatly, and whitening effect is good.
2, the present composition selects multiple gentle preparation of raw material to form, and drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, more preferable to the permeability of skin, is easily absorbed by the skin, improves whitening effect.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easy anaphylaxis and side reaction, improves the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should not being interpreted as, the scope of the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to the scope of the present invention.
Embodiment 1
1, by Cortex Cinnamomi 3 parts, Flos Magnoliae 18 parts, Flos Camelliae Japonicae 12 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, Herba Dendrobii 9 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, by the Cortex Cinnamomi extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Cortex Cinnamomi essence；By the Flos Magnoliae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Magnoliae essence；By the Flos Camelliae Japonicae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Camelliae Japonicae essence；By the tremella extract of step 1 gained at 62 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Tremella essence；By the Radix Platycodonis extract liquid of step 1 gained at 73 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Platycodonis essence；By the dendrobium extract of step 1 gained at 68 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Herba Dendrobii essence；By the Cortex Cinnamomi essence of gained, Flos Magnoliae essence, Flos Camelliae Japonicae essence, Tremella essence, Radix Platycodonis essence, Herba Dendrobii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
It is good that this cosmetic emulsion has whitening effect, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 2
1, by Cortex Cinnamomi 1 part, Flos Magnoliae 15 parts, Flos Camelliae Japonicae 12 parts, 9 parts of Tremella, Radix Platycodonis 2 parts, Herba Dendrobii 5 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, by the Cortex Cinnamomi extracting solution of step 1 gained at 75 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Cortex Cinnamomi essence；By the Flos Magnoliae extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Magnoliae essence；By the Flos Camelliae Japonicae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Camelliae Japonicae essence；By the tremella extract of step 1 gained at 60 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Tremella essence；By the Radix Platycodonis extract liquid of step 1 gained at 70 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Platycodonis essence；By the dendrobium extract of step 1 gained at 65 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Herba Dendrobii essence；By the Cortex Cinnamomi essence of gained, Flos Magnoliae essence, Flos Camelliae Japonicae essence, Tremella essence, Radix Platycodonis essence, Herba Dendrobii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
It is good that this cosmetic emulsion has whitening effect, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 3
1, by Cortex Cinnamomi 5 parts, Flos Magnoliae 25 parts, Flos Camelliae Japonicae 16 parts, 6 parts of Tremella, Radix Platycodonis 5 parts, Herba Dendrobii 10 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, by the Cortex Cinnamomi extracting solution of step 1 gained at 80 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Cortex Cinnamomi essence；By the Flos Magnoliae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Magnoliae essence；By the Flos Camelliae Japonicae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Camelliae Japonicae essence；By the tremella extract of step 1 gained at 65 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Tremella essence；By the Radix Platycodonis extract liquid of step 1 gained at 75 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Platycodonis essence；By the dendrobium extract of step 1 gained at 70 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Herba Dendrobii essence；By the Cortex Cinnamomi essence of gained, Flos Magnoliae essence, Flos Camelliae Japonicae essence, Tremella essence, Radix Platycodonis essence, Herba Dendrobii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
It is good that this cosmetic emulsion has whitening effect, has no side effect, the advantage of suitable various skin skin quality.
Comparative example 1
1, by Cortex Cinnamomi 3 parts, Flos Camelliae Japonicae 12 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, Herba Dendrobii 9 parts is pulverized after being separately dried, is extracted with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, by the Cortex Cinnamomi extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Cortex Cinnamomi essence；By the Flos Camelliae Japonicae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Camelliae Japonicae essence；By the tremella extract of step 1 gained at 62 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Tremella essence；By the Radix Platycodonis extract liquid of step 1 gained at 73 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Platycodonis essence；By the dendrobium extract of step 1 gained at 68 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Herba Dendrobii essence；By the Cortex Cinnamomi essence of gained, Flos Camelliae Japonicae essence, Tremella essence, Radix Platycodonis essence, Herba Dendrobii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
Comparative example 2
1, by Cortex Cinnamomi 3 parts, Flos Magnoliae 18 parts, Flos Camelliae Japonicae 12 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, pulverize after being separately dried, extract with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid；
2, by the Cortex Cinnamomi extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Cortex Cinnamomi essence；By the Flos Magnoliae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Magnoliae essence；By the Flos Camelliae Japonicae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Camelliae Japonicae essence；By the tremella extract of step 1 gained at 62 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Tremella essence；By the Radix Platycodonis extract liquid of step 1 gained at 73 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Platycodonis essence；By the Cortex Cinnamomi essence of gained, Flos Magnoliae essence, Flos Camelliae Japonicae essence, Tremella essence, Radix Platycodonis essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
Comparative example 3
1, by Cortex Cinnamomi 3 parts, Flos Magnoliae 10 parts, Flos Camelliae Japonicae 18 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, Herba Dendrobii 9 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, by the Cortex Cinnamomi extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Cortex Cinnamomi essence；By the Flos Magnoliae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Magnoliae essence；By the Flos Camelliae Japonicae extracting solution of step 1 gained at 72 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Flos Camelliae Japonicae essence；By the tremella extract of step 1 gained at 62 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Tremella essence；By the Radix Platycodonis extract liquid of step 1 gained at 73 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Platycodonis essence；By the dendrobium extract of step 1 gained at 68 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cool down to obtain Herba Dendrobii essence；By the Cortex Cinnamomi essence of gained, Flos Magnoliae essence, Flos Camelliae Japonicae essence, Tremella essence, Radix Platycodonis essence, Herba Dendrobii essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
Comparative example 4
1, by Cortex Cinnamomi 3 parts, Flos Magnoliae 18 parts, Flos Camelliae Japonicae 12 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, Herba Dendrobii 9 parts is pulverized after being separately dried, extract with ethanol solution and concentrate, obtaining Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
2, by the Cortex Cinnamomi extracting solution of step 1 gained, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae；
4, take whitening Chinese medicament compositions that percentage by weight is 10% respectively, the glycerol of 15%, the sorbitol olein of 10%, the purified water of 65% make skin-lightening cosmetic emulsion.
The skin-lightening cosmetic that above-described embodiment 1-3 and comparative example 1-4 obtain is tried out, randomly choose 800 volunteers, it is divided into 8 groups, wherein 1-7 uses the cosmetics that embodiment and comparative example prepare respectively, select the skin-lightening cosmetic that commercial type is best for 8th group, after using 15 days, skin detected and contrast, obtaining data below:
| Test group | Allergy number | TYR inhibition of enzyme activity rate (%) | Melanin reduction rate (%) |
| 1 | 0 | 73 | 11.4 |
| 2 | 0 | 71 | 11.2 |
| 3 | 0 | 71 | 10.8 |
| 4 | 9 | 32 | 2.3 |
| 5 | 5 | 46 | 4.5 |
| 6 | 6 | 55 | 6.2 |
| 7 | 1 | 67 | 10.1 |
| 8 | 0 | 61 | 8.5 |
From above proof test data, 1-3(embodiment 1-3) group have employed present composition raw material composition and the whitening Chinese medicament compositions for preparing of formula, there is synergistic function, the highest to maximum inhibition, the melanin reduction rate of TYR enzyme, whitening effect is notable, and drug effect is gentle, has no side effect, the lowest to the allergy rate of skin, it is suitable for various people and uses；4th group (comparative example 1) is not added with monarch drug Flos Magnoliae of the present invention, and compositions compatibility changes completely, and the property of medicine and drug effect change completely, and whitening effect is very poor, higher to skin allergy rate；5th group (comparative example 2) is not added with adjuvant drug Herba Dendrobii of the present invention, and compositions compatibility changes, and between each medical material, synergistic function disappears, and the property of medicine and drug effect change, and whitening effect is deteriorated, and improve skin allergy rate；6th group (comparative example 3) does not use the raw material number of the present composition, and Flos Camelliae Japonicae becomes monarch drug, and Flos Magnoliae becomes ministerial drug, and between each medical material, synergistic function disappears, and the property of medicine and drug effect are deteriorated, and whitening effect is poor, higher to skin allergy rate；The method that 7th group (comparative example 4) does not use the present invention to prepare compositions, but equally exist synergism between each medical material, there is preferable whitening effect equally, but the allergy rate of skin is increased；8th group is situation after existing skin-lightening cosmetic uses, and its whitening effect is general, and skin allergy rate is low.
Claims (10)
1. the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Cortex Cinnamomi 1-5 part, Flos Magnoliae 15-25 part, Flos Camelliae Japonicae 9-16 part, Tremella 6-9 part, Radix Platycodonis 2-5 part, Herba Dendrobii 5-10 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Cortex Cinnamomi 2-3 part, Flos Magnoliae 18-23 part, Flos Camelliae Japonicae 10-14 part, Tremella 8-9 part, Radix Platycodonis 2-3 part, Herba Dendrobii 8-10 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is to be prepared from by the raw material of following weight: Cortex Cinnamomi 3 parts, Flos Magnoliae 18 parts, Flos Camelliae Japonicae 12 parts, 8 parts of Tremella, Radix Platycodonis 3 parts, Herba Dendrobii 9 parts.
4., according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, its concrete preparation process is as follows:
(1), Cortex Cinnamomi, Flos Magnoliae, Flos Camelliae Japonicae, Tremella, Radix Platycodonis, Herba Dendrobii are separately dried after pulverize, extract and concentrate, obtain Cortex Cinnamomi extracting solution, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract；
(2), the Cortex Cinnamomi extracting solution of step 1 gained, Flos Magnoliae extracting solution, Flos Camelliae Japonicae extracting solution, tremella extract, Radix Platycodonis extract liquid, dendrobium extract are carried out maturation process respectively, carry out after cooling filtering, purifying to obtain each raw material essence, by each raw material essence mix homogeneously, and again carry out filtering, purifying, obtain mixing essence；
(3) the mixing essence, by step 2 obtained carries out homogenizing, obtains the Chinese medicine composition for skin-lightening cosmetic containing Flos Magnoliae.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Cortex Cinnamomi extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 3-4h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Flos Magnoliae extracting solution is 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Flos Camelliae Japonicae extract is 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of tremella extract is 80-85 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of Radix Platycodonis extract liquid is 70-75 DEG C, pressure is 0.1-0.2Mpa, the time is 2-3h.
The most according to claim 4, Chinese medicine composition, it is characterised in that in the preparation method step 2 of described compositions, the curing temperature of dendrobium extract is 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
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|---|---|---|---|---|
| JP2011511063A (en) * | 2009-01-23 | 2011-04-07 | バイオスペクトラム インコーポレイテッド | Skin whitening agent containing platicodine-D |
| CN104257597A (en) * | 2014-09-17 | 2015-01-07 | 郑州蓬泽生物科技开发研究院 | Dendrobe beauty fluid and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011511063A (en) * | 2009-01-23 | 2011-04-07 | バイオスペクトラム インコーポレイテッド | Skin whitening agent containing platicodine-D |
| CN104257597A (en) * | 2014-09-17 | 2015-01-07 | 郑州蓬泽生物科技开发研究院 | Dendrobe beauty fluid and preparation method thereof |
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Application publication date: 20160824 |