CN105853934A - Chinese patent medicine for activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain and preparation process of Chinese patent medicine - Google Patents

Chinese patent medicine for activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain and preparation process of Chinese patent medicine Download PDF

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Publication number
CN105853934A
CN105853934A CN201610400600.6A CN201610400600A CN105853934A CN 105853934 A CN105853934 A CN 105853934A CN 201610400600 A CN201610400600 A CN 201610400600A CN 105853934 A CN105853934 A CN 105853934A
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parts
chinese patent
patent medicine
circulation promoting
medicine
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宋林
王雪峰
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Foshan City Teng Rui Medicine Technology Co Ltd
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Foshan City Teng Rui Medicine Technology Co Ltd
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Priority to CN201610400600.6A priority Critical patent/CN105853934A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Chinese patent medicine for activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain and a preparation process of the Chinese patent medicine. The Chinese patent medicine is mainly prepared from, by mass, 30-100 parts of agrimonia pilosa ledeb, 30-100 parts of alumen, 30-100 parts of Semen Strychni Pulveratum, 30-100 parts of radix curcumae, 30-100 parts of trogopterus dung, 30-100 parts of niter, 30-100 parts of fried fructus aurantii and 30-100 parts of radix curcumae. The Chinese patent medicine for treating coronary heart disease is reasonable in formula, medicine materials are fewer but better, all the medicine materials have a synergistic effect, and the good functions of activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain can be generated.

Description

A kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving and preparation technology thereof
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving and preparation technology thereof.
Background technology
Blood circulation promoting and blood stasis dispelling, by that have dissipation role, maybe to attack the Drug therapy blood stasis disease by internal blood stasis method.
Have that unobstructed blood vessels, the dissipation stasis of blood be stagnant, the effect of menstruction regulating and pain relieving.The scope of application is very wide, if stasis blocking is in uncomfortable in chest pained, the cyanotic lips caused by the heart.Stasis blocking in the chest pain hemoptysis caused by lung, stasis blocking in the hypochondriac pain mass in the abdomen caused by liver, stasis blocking in caused by uterus lower abdomen ache, menoxenia, dysmenorrhea etc.;Stasis blocking is livid purple in the partial gall caused by limbs;Stasis blocking is in the hemiplegia etc. caused by venation.
Dispersing swelling and dissipating binds, one of traditional Chinese medical science resolving therapy.Use have removing toxic substances, invigorate blood circulation, the medicament composing prescription of the effect such as eliminating stagnation, dredging collateral, dissipate to swell with treatment disappear from the beginning of ulcer sores, poison, prevent into the method for the treatment of of pus.Be applicable to the diseases such as body surface carbuncle, furuncle, skin ulcer, erysipelas, multiple abscess, wart, tumor and acute appendicitis from the beginning of.
Removing toxic substances traditional Chinese medical term.Refer to release a kind of method for the treatment of of virus." malicious " has pyretic toxicity. severe pathogenic cold. and epidemic disease poison. diseases due to noxious agents produced by various parasites. noxious dampness. fire-toxin and alimentary toxicosis etc., because the state of an illness is different, there are the various distinct methods such as oral administration and external treatment.The most common with pyretic toxicity disease clinically.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation safely, effectively, having no side effect.
It is a further object to provide a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving and preparation technology thereof.
To achieve these goals, the present invention, according to theory of Chinese medical science, sums up clinical experience composition effective formula and drug for many years.
Its prescription is as follows:
Herba Agrimoniae 30~100 parts, Alumen 30~100 parts, Semen Strychni Pulveratum 30~100 parts, Radix Curcumae 30~100 parts, Oletum Trogopterori 30~100 parts, Sal Nitri 30~100 parts, Fructus Aurantii (parched) 30~100 parts, Radix Curcumae 30~100 parts.
The invention has the beneficial effects as follows:
1, the prescription of the present invention is compared with the prescription for the treatment of similar disease at present, reasonable recipe, and flavour of a drug are fewer but better, and each medicine produces synergism, can produce good blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, and detoxify analgesic efficacy.
2, the preparation process research design of the present invention is careful rationally, pharmacodynamics is combined with active component and has formulated extraction process, at good blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, impurity is farthest removed on the basis of removing toxic substances pain relieving, ensure that the drug effect of prescription, reduce again injection volume, the Study on Forming for preparation is laid a good foundation.
3, the present invention is blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, and removing toxic substances pain relieving Chinese patent medicine can also make dosage form series, including capsule, tablet, granule, soft capsule or other dosage forms etc..These dosage forms all have the advantages such as easy to use, good stability, quality controllability are good, patient adaptability is good.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, but is not limited thereto.
Embodiment 1
A kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain relieving Chinese patent medicine, is made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 55 parts, Alumen 55 parts, Semen Strychni Pulveratum 40 parts, Radix Curcumae 55 parts, Oletum Trogopterori 55 parts, 55 parts of Sal Nitri, Fructus Aurantii (parched) 90 parts, Radix Curcumae 55 parts.
Embodiment 2
A kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain relieving Chinese patent medicine, is made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 45 parts, Alumen 45 parts, Semen Strychni Pulveratum 45 parts, Radix Curcumae 45 parts, Oletum Trogopterori 45 parts, 45 parts of Sal Nitri, Fructus Aurantii (parched) 80 parts, Radix Curcumae 45 parts.
Embodiment 3
A kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain relieving Chinese patent medicine, is made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 65 parts, Alumen 65 parts, Semen Strychni Pulveratum 50 parts, Radix Curcumae 65 parts, Oletum Trogopterori 65 parts, 65 parts of Sal Nitri, Fructus Aurantii (parched) 90 parts, Radix Curcumae 65 parts.
Embodiment 4
A kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain relieving Chinese patent medicine, is made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 70 parts, Alumen 70 parts, Semen Strychni Pulveratum 40 parts, Radix Curcumae 70 parts, Oletum Trogopterori 70 parts, 70 parts of Sal Nitri, Fructus Aurantii (parched) 90 parts, Radix Curcumae 70 parts.
Embodiment 5 A kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the preparation of removing toxic substances acesodyne capsule
By following technique, the Chinese patent medicine of embodiment 1~4 can be made a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify acesodyne capsule, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Oletum Trogopterori, Alumen, Sal Nitri are ground into fine powder;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, is dried, standby after making fine powder;
(4) merge (2) and extract powder, add Semen Strychni Pulveratum mix homogeneously, add appropriate 95% ethanol and be mixed evenly to prepare suitable particulate, after drying, 1% magnesium stearate, 1% silicon dioxide mixing, fill capsule are added, make blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
Using method: oral.
Embodiment 6 One Plant blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the preparation of removing toxic substances tablet for alleviating pain
By following technique, the Chinese patent medicine of embodiment 1~4 can be made a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify tablet for alleviating pain, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Oletum Trogopterori, Alumen, Sal Nitri are ground into fine powder;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, is dried, standby after making fine powder;
(4) merge (2) and extract powder, add Semen Strychni Pulveratum mix homogeneously, add appropriate 95% ethanol and be mixed evenly to prepare suitable particulate, after drying, add 1% magnesium stearate, 1% silicon dioxide mixing, tabletting, make blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
Using method: oral.
Embodiment 7 One Plant blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the preparation of removing toxic substances pain-relieving powder for treating
By following technique, the Chinese patent medicine of embodiment 1~4 can be made a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain-relieving powder for treating, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Oletum Trogopterori, Alumen, Sal Nitri are ground into fine powder;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, is dried, standby after making fine powder;
(4) merge (2) and extract powder, add Semen Strychni Pulveratum mix homogeneously, 1% silicon dioxide mixing, pack, make blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
Using method: warm water is taken after mixing it with water.
Embodiment 8 One Plant blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the preparation of removing toxic substances pain relieving granule
By following technique, the Chinese patent medicine of embodiment 1~4 can be made a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain relieving granule, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Oletum Trogopterori, Alumen, Sal Nitri are ground into fine powder;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, is dried, standby after making fine powder;
(4) merge (2) and extract powder, add Semen Strychni Pulveratum mix homogeneously, add appropriate 95% ethanol and be mixed evenly to prepare suitable particulate, after drying, add 1% magnesium stearate, 1% silicon dioxide mixing, pack, make blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
Using method: warm water is taken after mixing it with water.
Embodiment 9 One Plant blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the preparation of removing toxic substances pain relieving soft capsules
By following technique, the Chinese patent medicine of embodiment 1~4 can be made a kind of blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, detoxify pain relieving soft capsules, specifically comprises the following steps that
(1) each medicine is weighed in proportion;
(2) Oletum Trogopterori, Alumen, Sal Nitri are ground into fine powder;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, is dried, standby after making fine powder;
(4) merge (2) and extract powder, add Semen Strychni Pulveratum mix homogeneously, add appropriate soybean oil, mixing, as content, prepare suitable rubber, encapsulating machine is made soft capsule, make blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
Using method: warm water is taken after mixing it with water.

Claims (8)

1. for a QI and blood deficiency, can blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving, it is characterised in that be mainly made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 30~100 parts, Alumen 30~100 parts, Semen Strychni Pulveratum 30~100 parts, Radix Curcumae 30~100 parts, Oletum Trogopterori 30~100 parts, Sal Nitri 30~100 parts, Fructus Aurantii (parched) 30~100 parts, Radix Curcumae 30~100 parts, add proper auxiliary materials and make 200 parts.
Blood circulation promoting and blood stasis dispelling the most according to claim 1, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving, it is characterised in that be mainly made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 40~80 parts, Alumen 40~80 parts, Semen Strychni Pulveratum 40~80 parts, Radix Curcumae 40~80 parts, Oletum Trogopterori 40~80 parts, Sal Nitri 40~80 parts, Fructus Aurantii (parched) 40~90 parts, Radix Curcumae 40~80 parts.
Blood circulation promoting and blood stasis dispelling the most according to claim 2, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving, it is characterised in that, mainly it is made up of the Chinese crude drug of following mass parts: Herba Agrimoniae 55 parts, Alumen 55 parts, Semen Strychni Pulveratum 40 parts, Radix Curcumae 55 parts, Oletum Trogopterori 55 parts, 55 parts of Sal Nitri, Fructus Aurantii (parched) 90 parts, Radix Curcumae 55 parts.
4. according to Chinese patent medicine described in any one of claims 1 to 3, it is characterised in that described Chinese patent medicine also can add the adjuvant pharmaceutically allowed and make oral formulations.
5. the blood circulation promoting and blood stasis dispelling described in any one of Claims 1 to 4, mass dissipating and swelling eliminating, the preparation method of the Chinese patent medicine of removing toxic substances pain relieving, comprise the steps:
(1) each medicine is weighed in proportion;
(2) Oletum Trogopterori, Alumen, Sal Nitri are ground into fine powder;
(3) remaining medical material boiling 2 times, decocting liquid, filter, filtrate is concentrated into the thick paste of relative density 1.30~1.32, is dried, standby after making fine powder;
(4) merge (2) and extract powder, add Semen Strychni Pulveratum and appropriate amount of auxiliary materials, make blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
Preparation method the most according to claim 5, step (3) is characterized in that, the condition of the soak by water technology of employing is: adds 8~10 times of water, soaks 0.5~1h.
Preparation method the most according to claim 5, it is characterised in that the technical conditions of step (3) described decocting cooking method are: decoct 2 hours for the first time, second time decocts 1 hour, filters, merging filtrate, concentrates, and is dried, and prepares extract powder.
Preparation method the most according to claim 5, it is characterised in that the concrete operations of step (4) are: select lactose or sucrose, mix homogeneously with extract extract powder, (2) Chinese medicine, makes blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, the Chinese patent medicine of removing toxic substances pain relieving.
CN201610400600.6A 2016-06-08 2016-06-08 Chinese patent medicine for activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain and preparation process of Chinese patent medicine Pending CN105853934A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610400600.6A CN105853934A (en) 2016-06-08 2016-06-08 Chinese patent medicine for activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain and preparation process of Chinese patent medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610400600.6A CN105853934A (en) 2016-06-08 2016-06-08 Chinese patent medicine for activating blood circulating to remove stasis, eliminating stagnation and removing swelling, and removing toxin and stopping pain and preparation process of Chinese patent medicine

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106176931A (en) * 2016-08-31 2016-12-07 佛山市弘泰药物研发有限公司 A kind of for blood circulation promoting and blood stasis dispelling, anginal Chinese patent medicine and preparation technology thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106176931A (en) * 2016-08-31 2016-12-07 佛山市弘泰药物研发有限公司 A kind of for blood circulation promoting and blood stasis dispelling, anginal Chinese patent medicine and preparation technology thereof

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Application publication date: 20160817