CN105816323A - Immune cell preparation back infusion bag - Google Patents
Immune cell preparation back infusion bag Download PDFInfo
- Publication number
- CN105816323A CN105816323A CN201610346669.5A CN201610346669A CN105816323A CN 105816323 A CN105816323 A CN 105816323A CN 201610346669 A CN201610346669 A CN 201610346669A CN 105816323 A CN105816323 A CN 105816323A
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- CN
- China
- Prior art keywords
- bag
- immunocyte
- stopping clamp
- liquid stopping
- saline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M2005/1401—Functional features
- A61M2005/1403—Flushing or purging
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention relates to an immune cell preparation back infusion bag which comprises an upper drug feeding end, an immune cell bag body, a lower drug feeding end, a lower triadius connection port, a silicone soft plug, a first liquid stop clamp, a lower cell pipe, a brine pipe, a second liquid stop clamp, a hanging hole, a brine short pipe, a third liquid stop clamp, an upper triadius connection port, an exhaust pipe, a syringe needle and a separable connector. The immune cell bag body is of a semielliptical structure, and the volume is 100-150 ml; the upper drug feeding end and the lower drug feeding end are oppositely located on the edges of the upper end and the lower opposite end of the immune cell bag body; the lower triadius connection port and the upper triadius connection port are located at the two opposite ends of the brine pipe respectively. By means of the immune cell preparation back infusion bag, preflush, back infusion and pipe flushing again can be completed integrally, full dose back infusion of the immune cell preparation is guaranteed, it is also convenient for nurses to conduct clinical operation, the risk of contamination caused by repeated puncture can be avoided quite well, and a safer and more convenient immune cell preparation back infusion method is provided for the clinic.
Description
Technical field
The invention belongs to medical field, relate to a kind of medical apparatus, be specifically related to a kind of immunocyte preparation and feed back bag.
Background technology
Cell therapy has been increasingly being applied to clinic, and autoimmune cell antineoplaston etc. is achieved with significant progress and development.After the immunocyte normal saline etc. prepared is suspended, inject in 100～250ml infusion bottles or transfusion bags, be that the most clinical conventional immunocyte feeds back mode.First normal saline washing pipe is connect with blood exchange transfusion set during feedback, then access cell feedback bottle to start to feed back, after bottle inner cell liquid infused, injecting in cell bottle with syringe extraction 20ml normal saline, the cell adhered to by bottle wall inputs internal after rinsing, finally, it is again coupled to normal saline bottle, blood exchange transfusion set's pipeline inner cell is all rinsed well, whole returning step, rush, feed back, rush the repeatable operation (up to 5 times) of bottle, again washing pipe in advance, considerably increase the risk of cell contamination and the workload of nurse.
Summary of the invention
For overcoming drawbacks described above, it is an object of the invention to provide a kind of simple in construction, easy to operate and will not produce pollution immunocyte preparation feed back bag.
A kind of immunocyte preparation feeds back bag, comprising: upper administration end, immunocyte bag, lower administration end, lower trident connectivity port, silica gel cork, the first liquid stopping clamp, lower cell pipeline, Brine Pipe, the second liquid stopping clamp, hanging hole, saline short tube, the 3rd liquid stopping clamp, upper trident connectivity port, exhaustor, syringe needle, separable joint；Described immunocyte bag is half elliptic structure, and volume is 100～150ml, and it is graduation mark unit-ID liquid level scale by 20ml；Described upper administration end and lower administration end are located relatively at the upper and lower opposite end edge of immunocyte bag；Lower trident connectivity port and upper trident connectivity port lay respectively at the opposite end of Brine Pipe；Described silica gel cork is fixed on the lower end of Brine Pipe；First liquid stopping clamp is positioned at the middle part of lower cell pipeline；One end of lower cell pipeline is connected with lower trident connectivity port, and the other end is connected with immunocyte bag；Described Brine Pipe is positioned at the outside of immunocyte bag, and its upper end is connected with saline short tube by upper trident connectivity port, and its bottom is connected with lower cell pipeline by lower trident connectivity port, a length of the 15 of Brine Pipe～35cm；Described second liquid stopping clamp is positioned at the middle part of Brine Pipe；Hanging hole is positioned at the upper end of immunocyte bag, is structure as a whole with immunocyte bag；Described 3rd liquid stopping clamp is positioned at the middle part of saline short tube；One end of saline short tube is connected with upper trident connectivity port, and the other end is connected with immunocyte bag, forms salt water passage；Described syringe needle is positioned at the upper top of Brine Pipe；Exhaustor is fixed and is positioned at the bottom of syringe needle and is fixed on Brine Pipe；Separable joint is between exhaustor and syringe needle, and is fixed on Brine Pipe.
Described immunocyte preparation feeds back the specifically used method of bag:
(1) the immunocyte preparation prepared is expelled in immunocyte bag 2 by upper administration end or lower administration end；
(2) blood exchange transfusion set inserts transfusion end silica gel cork, and syringe needle inserts normal saline bottle, opens the second liquid stopping clamp, is full of blood exchange transfusion set's pipeline by Brine Pipe by saline, after aerofluxus success, closes the second liquid stopping clamp；
(3) opening the first liquid stopping clamp, make lower cell pipeline open, after aerofluxus success, the immunocyte suspension in immunocyte bag starts infusion；
(4) after immunocyte bag bag inner cell suspension infused, close the first liquid stopping clamp, open the 3rd liquid stopping clamp, 60～120ml normal saline are made to enter in immunocyte bag by saline short tube, suitably dynamics rocks immunocyte bag, fully residual cells in immune cell bag is rinsed well and feeds back in the patient；
(5) after immunocyte feedback terminates, whole immunocyte preparation feedback bag is separated with blood exchange transfusion set, by separable joint, syringe needle is taken off from immunocyte preparation feedback bag simultaneously, process sharp instrument by medical waste regulation classification and feed back bag with immunocyte preparation.
Described lower cell pipeline, the length of saline short tube are 3～10cm.
Described liquid stopping clamp closes for directly folder, the liquid stopping clamp of unadjustable flow velocity.
Immunocyte preparation of the present invention feeds back bag, what energy was integrated completes pre-punching, feedback, again washing pipe, i.e. ensure that the full dose of immunocyte preparation feeds back, the more convenient clinical manipulation of nurse, avoid the pollution risk caused because of repeated localised puncture well, for clinic provide safer, easily immunocyte preparation feed back method.
Accompanying drawing explanation
Fig. 1 is the structural representation that immunocyte preparation of the present invention feeds back bag.
Detailed description of the invention
Below in conjunction with the accompanying drawings the present invention is described in detail.
As shown in Figure 1, a kind of immunocyte preparation feeds back bag, comprising: upper administration end 1, immunocyte bag 2, lower administration end 3, lower trident connectivity port 4, silica gel cork the 5, first liquid stopping clamp 6, lower cell pipeline 7, Brine Pipe the 8, second liquid stopping clamp 9, hanging hole 10, saline short tube the 11, the 3rd liquid stopping clamp 12, upper trident connectivity port 13, exhaustor 14, syringe needle 15, separable joint 16.Immunocyte bag 2 is in half elliptic structure, and volume is 100～150ml, and it is graduation mark unit-ID liquid level scale by 20ml.Upper administration end 1 and lower administration end 3 are located relatively at the upper and lower opposite end edge of immunocyte bag 2.Lower trident connectivity port 4 and upper trident connectivity port 13 lay respectively at the opposite end of Brine Pipe 8.Silica gel cork 5 is fixed on the lower end of Brine Pipe 8, connects the infusion end of blood exchange transfusion set.First liquid stopping clamp 6 is positioned at the middle part of lower cell pipeline 7；One end of lower cell pipeline 7 is connected with lower trident connectivity port 4, and the other end is connected with immunocyte bag 2.Brine Pipe 8 is positioned at the outside of immunocyte bag 2, and its upper end is connected with saline short tube 11 by upper trident connectivity port 13, and its bottom is connected with lower cell pipeline 7 by lower trident connectivity port 4, a length of the 15 of Brine Pipe 8～35cm.Second liquid stopping clamp 9 is positioned at the middle part of Brine Pipe 8.Hanging hole 10 is positioned at the upper end of immunocyte bag 2, is structure as a whole with immunocyte bag 2, is used for hanging whole immunocyte preparation and feeds back bag.3rd liquid stopping clamp 12 is positioned at the middle part of saline short tube 11；One end of saline short tube 11 is connected with upper trident connectivity port 13, and the other end is connected with immunocyte bag 2, forms saline line.Syringe needle 15, for commonly to connect puncture needle of infusion bottle (plastic spike or draw point), is positioned at the upper top of Brine Pipe 8；Exhaustor 14 is positioned at the bottom of syringe needle 15 and is fixed on Brine Pipe 8, and the air filter of this exhaustor 14 is provided with relief valve, and outside air can not enter pipeline.Separable joint 16, for spirally can turn on separating joint, between exhaustor 14 and syringe needle 15, and is fixed on Brine Pipe 8.Lower cell pipeline 7, the length of saline short tube 11 are 3～10cm.3 liquid stopping clamps are respectively provided with directly folder and close function, unadjustable flow velocity.
The specific implementation method using immunocyte preparation of the present invention to feed back bag is:
(1) the immunocyte preparation (cell suspension) prepared is expelled in immunocyte bag 2 by upper administration end 1 or lower administration end 3；
(2) blood exchange transfusion set inserts transfusion end silica gel cork 5, and syringe needle 15 inserts normal saline bottle, opens the second liquid stopping clamp 9, allows saline be full of blood exchange transfusion set's pipeline by Brine Pipe 8, after aerofluxus success, closes the second liquid stopping clamp 9；
(3) opening the first liquid stopping clamp 6, make lower cell pipeline 7 open, after aerofluxus success, the immunocyte suspension in immunocyte bag 2 starts infusion；
(4) after immunocyte bag 2 bag inner cell suspension infused, close the first liquid stopping clamp 6, open the 3rd liquid stopping clamp 12,60～120ml normal saline are made to enter in immunocyte bag 2 by saline short tube 11, suitably dynamics rocks immunocyte bag 2, fully residual cells in immune cell bag 2 is rinsed well and feeds back in the patient；
(5) after immunocyte feedback terminates, whole immunocyte preparation feedback bag is separated with blood exchange transfusion set, by separable joint 16, syringe needle 15 is taken off from immunocyte preparation feedback bag simultaneously, process sharp instrument by medical waste regulation classification and feed back bag with immunocyte preparation.
The present invention is disposable medical appliance, and patient is safe and convenient to use, will not worry to produce cross infection or superinfection, is that a kind of immunocyte preparation that medical personnel sum up through years'experiences feeds back bag.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (3)
1. an immunocyte preparation feeds back bag, it is characterised in that: described feedback bag includes: be above administered end (1), immunocyte bag (2), lower administration end (3), lower trident connectivity port (4), silica gel cork (5), the first liquid stopping clamp (6), lower cell pipeline (7), Brine Pipe (8), the second liquid stopping clamp (9), hanging hole (10), saline short tube (11), the 3rd liquid stopping clamp (12), upper trident connectivity port (13), exhaustor (14), syringe needle (15), separable joint (16)；Described immunocyte bag (2) is in half elliptic structure, and volume is 100～150ml, and it is graduation mark unit-ID liquid level scale by 20ml；Described upper administration end (1) and lower administration end (3) are located relatively at the upper and lower opposite end edge of immunocyte bag (2)；Lower trident connectivity port (4) and upper trident connectivity port (13) lay respectively at the opposite end of Brine Pipe (8)；Described silica gel cork (5) is fixed on the lower end of Brine Pipe (8)；First liquid stopping clamp (6) is positioned at the middle part of lower cell pipeline (7)；One end of lower cell pipeline (7) is connected with lower trident connectivity port (4), and the other end is connected with immunocyte bag (2)；Described Brine Pipe (8) is positioned at the outside of immunocyte bag (2), its upper end is connected with saline short tube (11) by upper trident connectivity port (13), its bottom is connected with lower cell pipeline (7) by lower trident connectivity port (4), a length of the 15～35cm of Brine Pipe (8)；Described second liquid stopping clamp (9) is positioned at the middle part of Brine Pipe (8)；Hanging hole (10) is positioned at the upper end of immunocyte bag (2), is structure as a whole with immunocyte bag (2)；Described 3rd liquid stopping clamp (12) is positioned at the middle part of saline short tube (11)；One end of saline short tube (11) is connected with upper trident connectivity port (13), and the other end is connected with immunocyte bag (2), forms salt water passage；Described syringe needle (15) is positioned at the upper top of Brine Pipe (8)；Exhaustor (14) is fixing to be positioned at the bottom of syringe needle (15) and is fixed on Brine Pipe (8)；Separable joint (16) is positioned between exhaustor (14) and syringe needle (15), and is fixed on Brine Pipe (8)；
Described immunocyte preparation feeds back the specifically used method of bag:
(1) the immunocyte preparation prepared is expelled in immunocyte bag (2) by upper administration end (1) or lower administration end (3)；
(2) blood exchange transfusion set inserting transfusion end silica gel cork (5), syringe needle (15) inserts normal saline bottle, opens the second liquid stopping clamp (9), allows saline be full of blood exchange transfusion set's pipeline by Brine Pipe (8), after aerofluxus success, closes the second liquid stopping clamp (9)；
(3) opening the first liquid stopping clamp (6), make lower cell pipeline (7) open, after aerofluxus success, the immunocyte suspension in immunocyte bag (2) starts infusion；
(4) after immunocyte bag (2) bag inner cell suspension infused, close the first liquid stopping clamp (6), open the 3rd liquid stopping clamp (12), 60～120ml normal saline are made to enter in immunocyte bag (2) by saline short tube (11), suitably dynamics rocks immunocyte bag (2), fully immune cell bag (2) interior residual cells is rinsed well and feeds back in the patient；
(5) after immunocyte feedback terminates, whole immunocyte preparation feedback bag is separated with blood exchange transfusion set, by separable joint (16), syringe needle (15) is taken off from immunocyte preparation feedback bag simultaneously, process sharp instrument by medical waste regulation classification and feed back bag with immunocyte preparation.
The most according to claim 1, immunocyte preparation feeds back bag, it is characterised in that: described lower cell pipeline (7), the length of saline short tube (11) are 3～10cm.
The most according to claim 1, immunocyte preparation feeds back bag, it is characterised in that: described liquid stopping clamp closes for directly folder, the liquid stopping clamp of unadjustable flow velocity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610346669.5A CN105816323B (en) | 2016-05-24 | 2016-05-24 | A kind of immunocyte preparation feedback bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610346669.5A CN105816323B (en) | 2016-05-24 | 2016-05-24 | A kind of immunocyte preparation feedback bag |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105816323A true CN105816323A (en) | 2016-08-03 |
| CN105816323B CN105816323B (en) | 2018-08-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610346669.5A Expired - Fee Related CN105816323B (en) | 2016-05-24 | 2016-05-24 | A kind of immunocyte preparation feedback bag |
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| CN (1) | CN105816323B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2437335Y (en) * | 2000-06-11 | 2001-07-04 | 彭顺秀 | Autoblood recovery reinfusion bag |
| CN201775834U (en) * | 2010-08-26 | 2011-03-30 | 汕头大学医学院第一附属医院 | Disposable hemopoietic stem cell infusion set |
| CN203790366U (en) * | 2014-04-22 | 2014-08-27 | 李爱凤 | Morphy dropper provided with wash pipe |
| CN203861672U (en) * | 2014-05-15 | 2014-10-08 | 中国人民解放军第四军医大学 | Disposable blood transfusion apparatus provided with Y-shaped joint |
| CN205019492U (en) * | 2015-09-17 | 2016-02-10 | 成都青山利康药业有限公司 | Pipeline device is washed in closed infusion |
-
2016
- 2016-05-24 CN CN201610346669.5A patent/CN105816323B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2437335Y (en) * | 2000-06-11 | 2001-07-04 | 彭顺秀 | Autoblood recovery reinfusion bag |
| CN201775834U (en) * | 2010-08-26 | 2011-03-30 | 汕头大学医学院第一附属医院 | Disposable hemopoietic stem cell infusion set |
| CN203790366U (en) * | 2014-04-22 | 2014-08-27 | 李爱凤 | Morphy dropper provided with wash pipe |
| CN203861672U (en) * | 2014-05-15 | 2014-10-08 | 中国人民解放军第四军医大学 | Disposable blood transfusion apparatus provided with Y-shaped joint |
| CN205019492U (en) * | 2015-09-17 | 2016-02-10 | 成都青山利康药业有限公司 | Pipeline device is washed in closed infusion |
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| Publication number | Publication date |
|---|---|
| CN105816323B (en) | 2018-08-14 |
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Effective date of registration: 20181019 Address after: 200120 C, 888, west two road, Nanhui new town, Pudong New Area, Shanghai Patentee after: IMPROVING LIFE BIOTECHNOLOGY (SHANGHAI) CO., LTD. Address before: 563003 149 Dalian Road, Huichuan District, Zunyi, Guizhou. Patentee before: Attached Hospital of Zunyi Medical College |
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Granted publication date: 20180814 Termination date: 20200524 |
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