CN105796857A - Traditional Chinese medicine preparation for treating neurofibromatosis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating neurofibromatosis.The traditional Chinese medicine preparation comprises 10-20g of selfheal spike, 10-20g of sargassum, 10-15g of tendril-leaved fritillary bulb, 10-20g of powdered shell of clam, 10-20g of fruit of trifoliate orange, 10-20g of Japanese ampelopsis root, 10-15g of niter, 10-15g of Chinese angelica, 10-20g of root of rehmannia, 8-15g of licorice root, 10-15g of Chinese rhubarb, 8-12g of centipede, 8-12g of white paeony root, 10-15g of nutgrass galingale rhizome, 8-12g of red date, 10-15g of rhizome of chuanxiong, 10-15g of honeysuckle flower, 8-12g of oyster, 10-20g of stiff silkworm and 10-15g of lithargite.Under synergistic action of all components of the formula, the traditional Chinese medicine preparation has the efficacy of clearing away heat and toxic materials, softening hardness to dissipate stagnation, promoting blood circulation to remove blood stasis and supporting the healthy energy, which is effective in treatment of neurofibromatosis without side effects, high in cure rate, not prone to recurrence, and worthy clinical popularization and application.

Description

A kind of Chinese medicine preparation treating multiple neurofibromatosis

Technical field

The invention belongs to the field of Chinese medicines, particularly relate to a kind of Chinese medicine system that can treat multiple neurofibromatosis Agent.

Background technology

Neurofibromatosis (Neurofibromatosis, NF) is with multiple neurofibromatosis and skin pigment The hereditary that speckle is characterized, originates from neuroepithelial tissue, mainly involve skin, peripheral nerve and in Pivot nervous system, is the one of neurocutaneous syndrome, how with Various Tissues such as skin, internal organs and connectives Pathological changes.Primary disease clinical manifestation is varied, and pathological changes can involve the multiple system of human body and position.At present, modern Therapeutic treatment is based on excision, but is only limitted to single huge tumor mass, and causes pain, malfunction With tend to the tumor group of pernicious change, and Postoperative recurrent rate is higher, feels simply helpless multiple especially.

Neurofibroma is that a kind of neural ectoderm that dominant inheritance causes is abnormal.Western medical treatment primary disease is predominantly Anti symptom treatment, hinders beautiful onlooker such as skin lesion or tumor mass increases and have pain to be suspected to have the person of cancerating and give excision, But Western medicine mostly can only respite partial symptoms, it is impossible to radical cure, the problem that there is drug resistance, operation is controlled Treat and spend height, risk big, and cure rate is low, be also easily recurrence.Therefore, instant invention overcomes above-mentioned all The most not enough, utilize this disease of pure treatment by Chinese herbs, the most evident in efficacy and safe and reliable, there is preferably popularization And use value.

Summary of the invention

Instant invention overcomes the most clinical conventional treatment defect existing for multiple neurofibromatosis medicine, carry Supplied a kind of determined curative effect, have no side effect, cure rate is high and is difficult to the pure Chinese medicinal preparation of recurrence.

The technical solution adopted in the present invention is:

A kind of Chinese medicine preparation treating multiple neurofibromatosis, it is characterised in that described Chinese medicine preparation by with The Chinese herb composition of lower weight portion:

Spica Prunellae 10-20 gram, Sargassum 10-20 gram, Bulbus Fritillariae Cirrhosae 10-15 gram, Pulvis concha Mactrae 10-20 gram, Fructus Aurantii 10-20 Gram, Radix Ampelopsis 10-20 gram, 10-15 gram of Sal Nitri, Radix Angelicae Sinensis 10-15 gram, 10-20 gram of the Radix Rehmanniae, Radix Glycyrrhizae 8-15 Gram, Radix Et Rhizoma Rhei 10-15 gram, Scolopendra 8-12 gram, Radix Paeoniae Alba 8-12 gram, Rhizoma Cyperi 10-15 gram, Fructus Jujubae 8-12 gram, Rhizoma Chuanxiong 10-15 gram, Flos Lonicerae 10-15 gram, Concha Ostreae 8-12 gram, Bombyx Batryticatus 10-20 gram, Lithargyrum 10-15 Gram.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Spica Prunellae 10 grams, Sargassum 10 grams, Bulbus Fritillariae Cirrhosae 10 grams, Pulvis concha Mactrae 10 grams, Fructus Aurantii 10 grams, Radix Ampelopsis 10 Gram, 10 grams of Sal Nitri, Radix Angelicae Sinensis 10 grams, 10 grams of the Radix Rehmanniae, 8 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Scolopendra 8 grams, The Radix Paeoniae Alba 8 grams, Rhizoma Cyperi 10 grams, Fructus Jujubae 8 grams, Rhizoma Chuanxiong 10 grams, Flos Lonicerae 10 grams, Concha Ostreae 8 grams, Bombyx Batryticatus 10 grams, Lithargyrum 10 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Spica Prunellae 12 grams, Sargassum 12 grams, Bulbus Fritillariae Cirrhosae 11 grams, Pulvis concha Mactrae 12 grams, Fructus Aurantii 12 grams, Radix Ampelopsis 12 Gram, 11 grams of Sal Nitri, Radix Angelicae Sinensis 11 grams, 12 grams of the Radix Rehmanniae, 10 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 11 grams, Scolopendra 8 grams, The Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 11 grams, Fructus Jujubae 6 grams, Rhizoma Chuanxiong 11 grams, Flos Lonicerae 11 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 12 grams, Lithargyrum 11 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Spica Prunellae 14 grams, Sargassum 14 grams, Bulbus Fritillariae Cirrhosae 12 grams, Pulvis concha Mactrae 14 grams, Fructus Aurantii 14 grams, Radix Ampelopsis 14 Gram, 12 grams of Sal Nitri, Radix Angelicae Sinensis 12 grams, 14 grams of the Radix Rehmanniae, 12 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 12 grams, Scolopendra 9 grams, The Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 12 grams, Fructus Jujubae 9 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 14 grams, Lithargyrum 12 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Spica Prunellae 16 grams, Sargassum 16 grams, Bulbus Fritillariae Cirrhosae 13 grams, Pulvis concha Mactrae 16 grams, Fructus Aurantii 16 grams, Radix Ampelopsis 16 Gram, 13 grams of Sal Nitri, Radix Angelicae Sinensis 13 grams, 16 grams of the Radix Rehmanniae, 13 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 13 grams, Scolopendra 10 grams, The Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 13 grams, Fructus Jujubae 10 grams, Rhizoma Chuanxiong 13 grams, Flos Lonicerae 13 grams, Concha Ostreae 10 grams, Bombyx Batryticatus 16 grams, Lithargyrum 13 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Spica Prunellae 18 grams, Sargassum 18 grams, Bulbus Fritillariae Cirrhosae 14 grams, Pulvis concha Mactrae 18 grams, Fructus Aurantii 18 grams, Radix Ampelopsis 18 Gram, 14 grams of Sal Nitri, Radix Angelicae Sinensis 104 grams, 18 grams of the Radix Rehmanniae, 14 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 14 grams, Scolopendra 11 grams, The Radix Paeoniae Alba 11 grams, Rhizoma Cyperi 14 grams, Fructus Jujubae 11 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 11 grams, Bombyx Batryticatus 18 grams, Lithargyrum 14 grams.

As a kind of prioritization scheme:

Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:

Spica Prunellae 20 grams, Sargassum 20 grams, Bulbus Fritillariae Cirrhosae 15 grams, Pulvis concha Mactrae 20 grams, Fructus Aurantii 20 grams, Radix Ampelopsis 20 Gram, 15 grams of Sal Nitri, Radix Angelicae Sinensis 15 grams, 20 grams of the Radix Rehmanniae, 15 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Scolopendra 12 grams, The Radix Paeoniae Alba 12 grams, Rhizoma Cyperi 15 grams, Fructus Jujubae 12 grams, Rhizoma Chuanxiong 15 grams, Flos Lonicerae 15 grams, Concha Ostreae 12 grams, Bombyx Batryticatus 20 grams, Lithargyrum 15 grams.

The instructions of taking of above-mentioned Chinese medicine preparation is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, according to biography The method of fried Chinese medicine of uniting takes its medicine juice, every day 1 dose, point sooner or later 2 clothes, within 1 month, is a course for the treatment of.

The raw material Chinese medicine of above-mentioned Chinese medicine preparation:

Radix Glycyrrhizae, sweet in the mouth, property is put down；GUIXIN, spleen, lung, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, dispel Phlegm and relieving cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription, have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that anticancer etc. Pharmacological action.Glycyrrhizic acid is topmost active component in Radix Glycyrrhizae.Glycyrrhizic acid and series of products thereof, to sarcoma, Growth of cancer cells has inhibitory action, and the suppression ratio of acquired immune deficiency syndrome (AIDS) is more up to 90%, has stronger increase human immunity Function.

Bulbus Fritillariae Cirrhosae, cool in nature, Gan Ping.Enter lung meridian, stomach warp.There is the merit of clearing heat, eliminating phlegm, relieving cough, can be used for treating Expectorant heat syndrome cough is breathed heavily, yellow thick card of coughing up phlegm；Hold concurrently again sugariness, therefore kind nourishing the lung to arrest cough, treatment lung has scorching cough expectorant The deficiency syndrome such as viscous card, and deficiency of YIN cough caused by dryness chronic cough less；Also has the merit of eliminating stagnation dissipating depression of QI, caused by treatment combination of phlegm and heat Uncomfortable in chest vexed card, and the disease such as scrofula sucutaneous nodule.

Pulvis concha Mactrae, bitter in the mouth, salty, property is put down.Enter lung, kidney channel.There is heat clearing away, diuretic, reduce phlegm, the merit of softening the hard mass Effect.Control heat-phlegm to breathe heavily and cough, edema, gonorrhea, wart, tumor, accumulation, blood agglomeration chest pain, dysentery, hemorrhoid, metrorrhagia, Leukorrhagia.

Fructus Aurantii, bitter in the mouth, pungent, sour, warm in nature；Return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, the merit of the stagnant relieving distension of row Effect, contained flavone compound has the important function such as antiinflammatory, antibacterial, antiviral, antitumor cell.

Radix Ampelopsis, bitter in the mouth, property is put down.Enter spleen, lung two warp.This product bitter cold is let out clearly, pungent scattered detumescence, therefore has heat clearing away Removing toxic substances, eliminating carbuncle eliminating stagnation, expelling pus and promoting granulation, the effect of reducing swelling and alleviating pain.

Sal Nitri, bitter in the mouth, salty, warm in nature.GUIXIN, spleen channel.Having to ward off dirty washs turbid, and removing mass of assaulting fortified position, diuretic rushes down Real, effect of removing toxic substances and promoting subsidence of swelling, therefore it is usually used in the cards such as sore throat, conjunctival congestion, sore swollen toxin.

Radix Angelicae Sinensis, acrid in the mouth, warm in nature；Return liver, the heart, spleen channel.There is replenishing and activating blood, effect of pain relieving intestine moistening. For blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatism Arthralgia pain, injury from falling down, ulcer sores.

The Radix Rehmanniae, sweet in the mouth, hardship, cold in nature；GUIXIN, liver, kidney channel.There is clearing away heat and cooling blood, the merit of YIN nourishing and the production of body fluid promoting Effect.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle Dermexanthesis.

Radix Et Rhizoma Rhei has anti-infectious function, the chrysophanic acid in Radix Et Rhizoma Rhei, rheum emodin, aloe-emodin, affects folic acid Enzyme system；Suppression bacterial nucleic acid and protein synthesis；Suppression bacterium living beings oxidase system；Induce interference Element, Anti-bacterium, antiviral and sensitive microbial, particularly to staphylococcus, Hemolytic streptococcus, pouring Sick coccus, diphtheria corynebacterium, Bacillus typhi, dysentery bacterium, influenza virus, Orphan virus, hepatitis B virus, Poliovirus, ameba, trichomonas vaginitis, schistosomicide and leptospira have and significantly press down Make and use.

The Radix Paeoniae Alba, cool in nature, bitter in the mouth acid, it is slightly cold, there is easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing receives the effects such as antiperspirant, Be applicable to fever due to yin deficiency, menoxenia, the chest and abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, Metrorrhagia, carry inferior disease.Paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves cardiac muscle Nutritional blood flow, expansion blood vessel, antagonism acute myocardial ischemia, suppression platelet aggregation, calmness, ease pain, solve Convulsion, antiulcer, the effect of regulation blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, large intestine Bacillus, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc..

Rhizoma Cyperi, acrid in the mouth, micro-hardship, sweet, property is put down；Enter liver spleen tri-jiao channel.There is dispersing the stagnated live-QI to relieve the stagnation of QI, menstruction regulating and pain relieving, Regulate the flow of vital energy adjust in effect, there is antiinflammatory, antibacterial action simultaneously.

Fructus Jujubae, sweet in the mouth, warm in nature；Return spleen, stomach, heart channel.There is invigorating the spleen and replenishing QI, effect of nourishing blood to tranquillize the mind.

Rhizoma Chuanxiong, acrid in the mouth, warm in nature；Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping. For pacifying nerve, positive wind syndrome of head is had a headache, and lump in the abdomen is suffered from abdominal pain, breast side of body twinge, tumbling and swelling, headache, rheumatism numbness Bitterly.

Flos Lonicerae is to various pathogens such as staphylococcus aureus, Hemolytic streptococcus, escherichia coli, dysentery Bacillus, vibrio cholera, Bacillus typhi, Salmonella paratyphi etc. all have certain inhibitory action, to streptococcus pneumoniae, Meningococcus, bacillus pyocyaneus, tubercule bacillus are the most effective；Flos Lonicerae decoct can promote the phagocytosis of leukocyte Function.Mouse peritoneal injection honeysuckle flower injection, also has the effect being obviously promoted inflammatory cell phagocytic function.

Concha Ostreae, salty in the mouth, puckery, cold nature；Return liver, kidney channel.There is suppressing the hyperactive liver and subsiding YANG, restrain astringent or styptic treatment for spontaneous sweating, softening the hard mass Effect of eliminating stagnation.

Lithargyrum, salty in the mouth, pungent, property is put down；Return liver, spleen channel, there is detumescence parasite killing, restrain anticorrosion, fall expectorant Relieving convulsion effect.Pharmacology test proves, during Lithargyrum cream 2% concentration in test tube to homocentricity trichophyton, Virgin color trichophyton, trichophyton and the little sporeformer of rust are inhibitory action；When 4% concentration, to cotton-shaped Epidermophyton, trichophyton gypseum, toes trichophyton etc. are all in inhibitory action.Water logging agent (1:3) is at test tube Interior also have inhibitory action in various degree to various skin fungus.

Spica Prunellae, acrid in the mouth, hardship, cold in nature；Return liver, gallbladder meridian.There is heat-clearing and toxic substances removing, liver heat removing and eyesight improving, softening the hard mass Effect of eliminating stagnation.Spica Prunellae mainly contains triterpenes and glycoside, flavonoid, coumarin, organic acid, waves The chemical composition such as hair oil and polysaccharide.Containing multiple triterpenes components, predominantly oleanane type.Folium Vaccinii vitis-idaeae alkane type With the pentacyclic triterpene such as feather fan type, also containing six ring triterpenes, more than totally 30 kinds.Spica Prunellae has significant antiinflammatory and makees With, Oleum Tiglii induced mice ear swelling can be significantly inhibited, to Rat Carrageenan colloidality and paw swelling induced by egg mould Type and rat granuloma swell and all have obvious inhibitory action.Spica Prunellae water decoction has broad spectrum antibiotic activity, Having slight anti-gonococcus effect, its extracting solution is to escherichia coli, staphylococcus aureus, bacillus subtilis, green grass or young crops Mould and aspergillus niger all has obvious bacteriostasis.For to prevent the antibacterial superinfection to skin corium in skin allergy Stimulate as conventional antiinflammatory and reduction with injury therefore employing Spica Prunellae extract.

Sargassum, bitter in the mouth, salty, cold in nature；Return lung, stomach, kidney channel.There is hard masses softening and resolving, the merit of expectorant diuretic Effect.Modern pharmacology proves, the close glycoprotein of Sargassum not only can be with coagulation erythrocyte, tumor cell, lymph Ball, yeast, marine bacteria and unicellular blue-green alge, also can promote mouselet and human lymphoid's ball splitting action, Improve body immunity.It addition, the fucose of Sargassum has obvious antitumor and anticoagulant active effect.

Scolopendra, acrid in the mouth, warm in nature；Return Liver Channel.There is relieving spasm by subduing liver-wind, detoxicating and resolving stagnation of pathogens, effect of removing obstruction in the collateral to relieve pain. " Records of Tradition Chinese and Western Medicine in Combination " carries: " Scolopendra, walks the power steepest altered, interior and internal organs, outer and meridians, all QI and blood It all can be opened in place of cohesion." modern pharmacological research confirmation, the Zhijing San being made up of Scolopendra, Scorpio prescription, have Preferably anticonvulsant action；Various skin fungus all there is inhibitory action in various degree；Scolopendra Hirudo is injected The multiple cancerous cell such as ehrlich carcinoma, leukemia, hepatocarcinoma, breast carcinoma, cervical cancer, gastric cancer are all had and press down by liquid Make and use；Reticuloendothelial cell function there is potentiation.

Bombyx Batryticatus, salty in the mouth, pungent, property is put down, and enters liver, lung two warp, can endogenous wind stopping relieving convulsion, can relieve internal heat again anticancer, Mass dissipating and swelling eliminating, arresting convulsion of reducing phlegm, therefore it is the most suitable that infantile convulsion, epilepsy are held under the arm the hot person of expectorant.Modern pharmacology proves, Bombyx Batryticatus alcohol water-leach liquor all has hypnosis, anticonvulsant action to mice, rabbit；Its extracting solution in vivo, outer all There is stronger anticoagulation；Bombyx Batryticatus powder has preferable hypoglycemic activity；In vitro tests, to Staphylococcus aureus Bacterium, bacillus pyocyaneus have slight bacteriostasis, can suppress the breathing of human hepatoma cell outside its alcohol extraction object, Can be used for the treatment of rectum tumor type polyp.

Traditional Chinese Medicine is thought, the multiple neurofibroma of brain be formed as internal damage by the excessive seven emotions, make function Imbalance, exopathogen invades in addition, and cold and heat are fought mutually, stop in expectorant is turbid, gathers in health for a long time, retardance meridians and send out in Skin, thus control to neutralize QI and blood, dredge the meridian passage, softening the hard mass internal diabetes are main.

In Chinese medicine preparation of the present invention, Radix Et Rhizoma Rhei, Radix Ampelopsis, Flos Lonicerae, Lithargyrum, Spica Prunellae heat-clearing and toxic substances removing, disappear Dissipate carbuncle, effectively dispel internal toxic dampness and heat, reach anti-inflammation and sterilization, antineoplastic action；Sargassum, Pulvis concha Mactrae Hard masses softening and resolving, expectorant diuretic, suppresses tumor growth, transfer, promotes reducing and disappearing of tumor body；Sal Nitri by Cold, removing mass, knot of assaulting fortified position, dredging water passages, removing the relative excess are stagnant, accelerate tumor body carbuncle poison from internal discharge；Radix Angelicae Sinensis, The Radix Rehmanniae, Fructus Jujubae, Radix Paeoniae Alba replenishing and activating blood, nourish blood yin fluid astringing, and conditioning human body yang blood and qi is unbalance；Rhizoma Cyperi, Fructus Aurantii Dispersing the stagnated live-QI to relieve the stagnation of QI, promoting QI to circulate and dispersing the agglomeration of the pathogens, stomach function regulating spleen invigorating, conditioning viscera；Rhizoma Chuanxiong is walked to alter and circulation of qi promoting, and blood circulation promoting and blood stasis dispelling is with only Blood, the up head and dispel the wind, under enter the sea of blood with regulating menstruation, and outer thorough fur, bypass extremity, for the gas in blood Medicine；Bulbus Fritillariae Cirrhosae removing heat-phlegm, lung qi dispersing cough-relieving, eliminate the scrofula of internal phlegm-fire pent-up；Concha Ostreae suppressing the hyperactive liver and subsiding YANG, receipts Hold back astringent or styptic treatment for spontaneous sweating, hard masses softening and resolving, enhance metabolism, improve body immunity.Scolopendra, Bombyx Batryticatus only can relieve dizziness, high fever, infantile convulsions, epilepsy, etc. Convulsion, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain, can stimulating Qi of meridian, dredging the meridian, promote QI-blood circulation, make the efficacy of a drug straight Reach disease institute, anticancer dispersing tumor.Radix Glycyrrhizae can invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, contained glycyrrhizic acid can suppress sarcoma, Growth of cancer cells, again can coordinating the actions of various ingredients in a prescription, make the bias of all medicines be alleviated, and be allowed to coordinated with each other, jointly Complete its therapeutical effect.Full side yang blood and qi is all adjusted, and invigorating middle warmer has rushes down, giving consideration to both the incidental and fundamental, card medicine phase and, effect is such as Small wooden raft drum, plays the merit of heat-clearing and toxic substances removing, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, strengthening the body resistance altogether, has dispersing swelling and dissipating binds, Eleminating phlegm and freeing channels, again can across-the-board regulation incretion balance, the cancerous protuberance that reaches to disappear, the cancer pain that disappears, dissipate the effect of tumor, And then fundamentally release patient's misery or old complaint.

For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected the 45 multiple god of example Clinical trial, the maleest 38 examples, female 22 example is carried out through fibroma patient；Age 12-66 year.Wherein lose Transmissibility patient 5 example, nongenetic 40 example, early stage patient 20 example, patient in mid-term 19 example, patients with terminal 6 Example.All patient clinical symptoms: tumor is multiple, many persons reach hundreds of, can grow everywhere at whole body. Not of uniform size, little such as beans, good size and spaced farapart is big such as egg, poor growth.Big protrudes from body more Table, it is possible in flakes, the growth of in bulk, makes skin and hypodermic layer is plump, sagging, wrinkle in rubber shape.Swollen Tumor is soft, and without touching a tender spot, skin often has the pigmentation that degree differs.

Therapeutic Method:

Take Chinese medicine preparation of the present invention, take Spica Prunellae 14 grams, Sargassum 14 grams, Bulbus Fritillariae Cirrhosae 12 grams, Pulvis concha Mactrae 14 Gram, Fructus Aurantii 14 grams, Radix Ampelopsis 14 grams, 12 grams of Sal Nitri, Radix Angelicae Sinensis 12 grams, 14 grams of the Radix Rehmanniae, 12 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 12 grams, Scolopendra 9 grams, the Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 12 grams, Fructus Jujubae 9 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 14 grams, Lithargyrum 12 grams (with disease add and subtract), by Chinese medicine decocting side After method takes its medicine juice, point morning, 2 decoction being taken warmly in evening.Every day 1 dose, 1 month is 1 course for the treatment of.

Criterion of therapeutical effect:

Cure: mottle, tumor body disappear for main standard；

Effective: mottle color is thin out, color lump reduces, tumor body diminishes；

Effective: mottle, tumor body reduce；

Invalid: mottle, tumor body do not change.

Efficacy analysis:

After taking medicine of the present invention, the biggest number patient symptom after 1-2 the course for the treatment of is improved notable.Through medication After the treatment of 4-6 the course for the treatment of, through analytical calculation, in early days, mid-term, patients with terminal rehabilitation rate be respectively as follows: 94.6%, 79.2%, 60.6%.In 45 example patients, cure 23 examples, cure rate 51.1%, effective 11 examples, effective 7 Example, invalid 4 examples, total effective rate is 91.1%.Observed and recorded in therapeutic process, is taking this without patient After invention medicine, obvious adverse reaction occurs, show that this medicine is the medicine for the treatment of neurofibromatosis effective and safe.

Result shows, the Chinese medicine preparation of the present invention can effectively hit pathogenesis, rectifier yin-yang, improves Body immunity, activation equipment soma, prevent sick cell from spreading, and strangle sick cell, reach god Recovery purpose through tip and nerve fiber.Have evident in efficacy for treating multiple neurofibromatosis, nothing Side effect, cure rate is high, be difficult to the advantages such as recurrence, clinic promotion and application.

Detailed description of the invention

Embodiment 1: a kind of Chinese medicine preparation treating multiple neurofibromatosis, chooses Spica Prunellae 10 grams, sea 10 grams of algae, Bulbus Fritillariae Cirrhosae 10 grams, Pulvis concha Mactrae 10 grams, Fructus Aurantii 10 grams, Radix Ampelopsis 10 grams, 10 grams of Sal Nitri, Radix Angelicae Sinensis 10 grams, 10 grams of the Radix Rehmanniae, 8 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Scolopendra 8 grams, the Radix Paeoniae Alba 8 grams, Rhizoma Cyperi 10 grams, Fructus Jujubae 8 grams, Rhizoma Chuanxiong 10 grams, Flos Lonicerae 10 grams, Concha Ostreae 8 grams, Bombyx Batryticatus 10 grams, Lithargyrum 10 grams.

Embodiment 2: a kind of Chinese medicine preparation treating multiple neurofibromatosis, chooses Spica Prunellae 12 grams, sea 12 grams of algae, Bulbus Fritillariae Cirrhosae 11 grams, Pulvis concha Mactrae 12 grams, Fructus Aurantii 12 grams, Radix Ampelopsis 12 grams, 11 grams of Sal Nitri, Radix Angelicae Sinensis 11 grams, 12 grams of the Radix Rehmanniae, 10 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 11 grams, Scolopendra 8 grams, the Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 11 grams, Fructus Jujubae 6 grams, Rhizoma Chuanxiong 11 grams, Flos Lonicerae 11 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 12 grams, Lithargyrum 11 grams.

Embodiment 3: a kind of Chinese medicine preparation treating multiple neurofibromatosis, chooses Spica Prunellae 14 grams, sea 14 grams of algae, Bulbus Fritillariae Cirrhosae 12 grams, Pulvis concha Mactrae 14 grams, Fructus Aurantii 14 grams, Radix Ampelopsis 14 grams, 12 grams of Sal Nitri, Radix Angelicae Sinensis 12 grams, 14 grams of the Radix Rehmanniae, 12 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 12 grams, Scolopendra 9 grams, the Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 12 grams, Fructus Jujubae 9 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 14 grams, Lithargyrum 12 grams.

Embodiment 4: a kind of Chinese medicine preparation treating multiple neurofibromatosis, chooses Spica Prunellae 16 grams, sea 16 grams of algae, Bulbus Fritillariae Cirrhosae 13 grams, Pulvis concha Mactrae 16 grams, Fructus Aurantii 16 grams, Radix Ampelopsis 16 grams, 13 grams of Sal Nitri, Radix Angelicae Sinensis 13 grams, 16 grams of the Radix Rehmanniae, 13 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 13 grams, Scolopendra 10 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 13 Gram, Fructus Jujubae 10 grams, Rhizoma Chuanxiong 13 grams, Flos Lonicerae 13 grams, Concha Ostreae 10 grams, Bombyx Batryticatus 16 grams, Lithargyrum 13 Gram.

Embodiment 5: a kind of Chinese medicine preparation treating multiple neurofibromatosis, chooses Spica Prunellae 18 grams, sea 18 grams of algae, Bulbus Fritillariae Cirrhosae 14 grams, Pulvis concha Mactrae 18 grams, Fructus Aurantii 18 grams, Radix Ampelopsis 18 grams, 14 grams of Sal Nitri, Radix Angelicae Sinensis 104 grams, 18 grams of the Radix Rehmanniae, 14 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 14 grams, Scolopendra 11 grams, the Radix Paeoniae Alba 11 grams, Rhizoma Cyperi 14 Gram, Fructus Jujubae 11 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 11 grams, Bombyx Batryticatus 18 grams, Lithargyrum 14 Gram.

Embodiment 6: a kind of Chinese medicine preparation treating multiple neurofibromatosis, chooses Spica Prunellae 20 grams, sea 20 grams of algae, Bulbus Fritillariae Cirrhosae 15 grams, Pulvis concha Mactrae 20 grams, Fructus Aurantii 20 grams, Radix Ampelopsis 20 grams, 15 grams of Sal Nitri, Radix Angelicae Sinensis 15 grams, 20 grams of the Radix Rehmanniae, 15 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Scolopendra 12 grams, the Radix Paeoniae Alba 12 grams, Rhizoma Cyperi 15 Gram, Fructus Jujubae 12 grams, Rhizoma Chuanxiong 15 grams, Flos Lonicerae 15 grams, Concha Ostreae 12 grams, Bombyx Batryticatus 20 grams, Lithargyrum 15 Gram.

Below by concrete case, the Chinese medicine preparation curative effect of the present invention is verified further:

Case 1

Patient Wang, female, 25 years old, little pimple occurs at abdominal part coffee speckle during patient 10 years old, be gradually increased to The big lesser tubercle of Semen Glycines, increasing number.Once at certain hospital admission, pathologic finding is shown in volume mastocyte, diagnosis For " nerve fibroma (non-malignant) ".Cranial Computed Tomography and MRI no abnormality seen, get rid of metastasis in brain, Do not take remedy measures.Tuberosity spreads all over whole body in recent years, seeks advice from all without effective Therapeutic Method through multiple hospitals, Recommend to take Drug therapy of the present invention through people.Observe patients symptomatic, take Spica Prunellae 12 grams, Sargassum 12 grams, Bulbus Fritillariae Cirrhosae 11 grams, Pulvis concha Mactrae 12 grams, Fructus Aurantii 12 grams, Radix Ampelopsis 12 grams, 11 grams of Sal Nitri, Radix Angelicae Sinensis 11 grams, life 12 grams of ground, 10 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 11 grams, Scolopendra 8 grams, the Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 11 grams, Fructus Jujubae 6 Gram, Rhizoma Chuanxiong 11 grams, Flos Lonicerae 11 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 12 grams, Lithargyrum 11 grams, after decocting Take, every day 1 dose, point twice decoction being taken warmly of morning and evening.After 1 course for the treatment of, tuberosity has the trend of reducing, and continues medication 2 The individual course for the treatment of, patient's major part tuberosity is the most flat, and that comforts is still uneven, still has pigmentation, coffee speckle substantially to turn Light.After continuing medication one month in addition after treatment, patient fully recovers.Effect of follow-up visit by telephone has no recurrence half a year.

Case 2

Dong patient, man, 25 years old, patient started the long sarcoma having Fructus Vitis viniferae size on right arm before 4 years, with After grow big and small sarcoma successively in the place such as waist, buttocks, pressing is without obvious pain, through locality The People's Hospital is diagnosed as multiple neurofibromatosis, once takes hospital and opens drug administration and within three months, have no obvious Improve.Then, under friend recommendation, take treatment by Chinese herbs of the present invention, take Spica Prunellae 16 grams, Sargassum 16 grams, Bulbus Fritillariae Cirrhosae 13 grams, Pulvis concha Mactrae 16 grams, Fructus Aurantii 16 grams, Radix Ampelopsis 16 grams, 13 grams of Sal Nitri, Radix Angelicae Sinensis 13 grams, life 16 grams of ground, 13 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 13 grams, Scolopendra 10 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 13 grams, Fructus Jujubae 10 grams, Rhizoma Chuanxiong 13 grams, Flos Lonicerae 13 grams, Concha Ostreae 10 grams, Bombyx Batryticatus 16 grams, Lithargyrum 13 grams, decocting After take, every day 1 dose, point sooner or later twice decoction being taken warmly.After 1 course for the treatment of, neurofibroma diameter starts zooming out, After 2 courses for the treatment of, big tumor body disappears, and waist also has the neurofibroma that several Semen phaseoli radiati is big, then with 1 treatment Journey is treated.Patient's neurofibroma of making a phone call is wholly absent.For consolidating curative effect, residue medicine is continued clothes Complete.Effect of follow-up visit by telephone has no recurrence half a year.

Case 3

Grandson patient, man, 21 years old, patient before 2 years examination in hospital suffer from multiple neurofibromatosis, only see It is big that the fibromatosis of enlargement all over sends out density, tumor size, big such as egg, little such as Semen Glycines, stretches Hands is the most accessible, and patient is the most painful, lethargy, takes western medicine many for half a year, and curative effect is not very Substantially.Recommend through people, take treatment by Chinese herbs of the present invention, take Spica Prunellae 20 grams, Sargassum 20 grams, Bulbus Fritillariae Cirrhosae 15 Gram, Pulvis concha Mactrae 20 grams, Fructus Aurantii 20 grams, Radix Ampelopsis 20 grams, 15 grams of Sal Nitri, Radix Angelicae Sinensis 15 grams, 20 grams of the Radix Rehmanniae, 15 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Scolopendra 12 grams, the Radix Paeoniae Alba 12 grams, Rhizoma Cyperi 15 grams, Fructus Jujubae 12 grams, river Rhizome of chuanxiong 15 grams, Flos Lonicerae 15 grams, Concha Ostreae 12 grams, Bombyx Batryticatus 20 grams, Lithargyrum 15 grams, take after decocting, Every day 1 dose, point twice decoction being taken warmly of morning and evening.Through the treatment of 1 course for the treatment of, little tumor disappearance quickly, greatly Tumor starts zooming out substantially, and patient finally fully recovers through trimestral treatment.

Claims (7)

1. the Chinese medicine preparation treating multiple neurofibromatosis, it is characterised in that described Chinese medicine preparation by The Chinese herb composition of following weight portion:

Spica Prunellae 10-20 gram, Sargassum 10-20 gram, Bulbus Fritillariae Cirrhosae 10-15 gram, Pulvis concha Mactrae 10-20 gram, Fructus Aurantii 10-20 Gram, Radix Ampelopsis 10-20 gram, 10-15 gram of Sal Nitri, Radix Angelicae Sinensis 10-15 gram, 10-20 gram of the Radix Rehmanniae, Radix Glycyrrhizae 8-15 Gram, Radix Et Rhizoma Rhei 10-15 gram, Scolopendra 8-12 gram, Radix Paeoniae Alba 8-12 gram, Rhizoma Cyperi 10-15 gram, Fructus Jujubae 8-12 gram, Rhizoma Chuanxiong 10-15 gram, Flos Lonicerae 10-15 gram, Concha Ostreae 8-12 gram, Bombyx Batryticatus 10-20 gram, Lithargyrum 10-15 Gram.

Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is by following heavy The Chinese herb composition of amount part:

Spica Prunellae 10 grams, Sargassum 10 grams, Bulbus Fritillariae Cirrhosae 10 grams, Pulvis concha Mactrae 10 grams, Fructus Aurantii 10 grams, Radix Ampelopsis 10 Gram, 10 grams of Sal Nitri, Radix Angelicae Sinensis 10 grams, 10 grams of the Radix Rehmanniae, 8 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Scolopendra 8 grams, The Radix Paeoniae Alba 8 grams, Rhizoma Cyperi 10 grams, Fructus Jujubae 8 grams, Rhizoma Chuanxiong 10 grams, Flos Lonicerae 10 grams, Concha Ostreae 8 grams, Bombyx Batryticatus 10 grams, Lithargyrum 10 grams.

Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is by following heavy The Chinese herb composition of amount part:

Spica Prunellae 12 grams, Sargassum 12 grams, Bulbus Fritillariae Cirrhosae 11 grams, Pulvis concha Mactrae 12 grams, Fructus Aurantii 12 grams, Radix Ampelopsis 12 Gram, 11 grams of Sal Nitri, Radix Angelicae Sinensis 11 grams, 12 grams of the Radix Rehmanniae, 10 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 11 grams, Scolopendra 8 grams, The Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 11 grams, Fructus Jujubae 6 grams, Rhizoma Chuanxiong 11 grams, Flos Lonicerae 11 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 12 grams, Lithargyrum 11 grams.

Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is by following heavy The Chinese herb composition of amount part:

Spica Prunellae 14 grams, Sargassum 14 grams, Bulbus Fritillariae Cirrhosae 12 grams, Pulvis concha Mactrae 14 grams, Fructus Aurantii 14 grams, Radix Ampelopsis 14 Gram, 12 grams of Sal Nitri, Radix Angelicae Sinensis 12 grams, 14 grams of the Radix Rehmanniae, 12 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 12 grams, Scolopendra 9 grams, The Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 12 grams, Fructus Jujubae 9 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 9 grams, Bombyx Batryticatus 14 grams, Lithargyrum 12 grams.

Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is by following heavy The Chinese herb composition of amount part:

Spica Prunellae 16 grams, Sargassum 16 grams, Bulbus Fritillariae Cirrhosae 13 grams, Pulvis concha Mactrae 16 grams, Fructus Aurantii 16 grams, Radix Ampelopsis 16 Gram, 13 grams of Sal Nitri, Radix Angelicae Sinensis 13 grams, 16 grams of the Radix Rehmanniae, 13 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 13 grams, Scolopendra 10 grams, The Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 13 grams, Fructus Jujubae 10 grams, Rhizoma Chuanxiong 13 grams, Flos Lonicerae 13 grams, Concha Ostreae 10 grams, Bombyx Batryticatus 16 grams, Lithargyrum 13 grams.

Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is by following heavy The Chinese herb composition of amount part:

Spica Prunellae 18 grams, Sargassum 18 grams, Bulbus Fritillariae Cirrhosae 14 grams, Pulvis concha Mactrae 18 grams, Fructus Aurantii 18 grams, Radix Ampelopsis 18 Gram, 14 grams of Sal Nitri, Radix Angelicae Sinensis 104 grams, 18 grams of the Radix Rehmanniae, 14 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 14 grams, Scolopendra 11 grams, The Radix Paeoniae Alba 11 grams, Rhizoma Cyperi 14 grams, Fructus Jujubae 11 grams, Rhizoma Chuanxiong 14 grams, Flos Lonicerae 14 grams, Concha Ostreae 11 grams, Bombyx Batryticatus 18 grams, Lithargyrum 14 grams.

Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation is by following heavy The Chinese herb composition of amount part:

Spica Prunellae 20 grams, Sargassum 20 grams, Bulbus Fritillariae Cirrhosae 15 grams, Pulvis concha Mactrae 20 grams, Fructus Aurantii 20 grams, Radix Ampelopsis 20 Gram, 15 grams of Sal Nitri, Radix Angelicae Sinensis 15 grams, 20 grams of the Radix Rehmanniae, 15 grams of Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Scolopendra 12 grams, The Radix Paeoniae Alba 12 grams, Rhizoma Cyperi 15 grams, Fructus Jujubae 12 grams, Rhizoma Chuanxiong 15 grams, Flos Lonicerae 15 grams, Concha Ostreae 12 grams, Bombyx Batryticatus 20 grams, Lithargyrum 15 grams.