CN105770845A - 一种治疗中风瘫痪的中成药及其制备方法 - Google Patents

一种治疗中风瘫痪的中成药及其制备方法 Download PDF

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CN105770845A
CN105770845A CN201610326465.5A CN201610326465A CN105770845A CN 105770845 A CN105770845 A CN 105770845A CN 201610326465 A CN201610326465 A CN 201610326465A CN 105770845 A CN105770845 A CN 105770845A
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radix
rhizoma
fructus
herba
cortex
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王顺
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Abstract

本发明涉及一种治疗中风瘫痪的中成药及其制备方法,属于药品(中成药)技术领域。其特征在于组成原料由山枣皮、柴胡、紫草、清风藤、防风、白芍、青皮、茵陈、鸡血藤、天南星、五加皮、木香、粉防已、怀牛膝、制半夏、玄参、厚朴、白花蛇舌草、桑枝、天竺黄、龟甲、人参等组成。可制成蜜丸和粉剂,功效:治疗中风瘫痪、脑瘫、癫狂、癫痫、高血压、头痛眩晕、颈腰椎骨质增生、肝炎;具有祛风舒筋、滋补肝肾、祛痰渗湿、活血化瘀、大补气血、解痉除抽、降压除栓、通便排毒、清热解毒、补气健脾、理气解郁等功效,也适用于因风湿、类风湿引起的风湿关节炎、风湿心脏病等慢性疑难重病。

Description

一种治疗中风瘫痪的中成药及其制备方法
技术领域:本发明涉及一种治疗中风瘫痪的中成药及其制备方法,属于药品(中成药)技术领域。
背景技术:经专利检索,专利号为CN104840600A一种治疗瘫痪的中药制剂,包括如下原料药:狗全骨一只、黄芪72g、人参20g、熟地30g、防风45g、肉苁蓉25g、党参60g、桔梗64g、甘草60g,行气化滞,活血散瘀,软坚散节,生精补髓,健脾活络,开宣肺气,祛风解表,清热解毒,滋阴补血为一体化治疗手段;专利号CN104825933A一种治疗瘫痪的中药制剂及其制备方法,药材主要有:怀牛膝、赭石、牡蛎、茵陈、天冬、赤芍、黄柏、五味子、龙骨、杜仲、茯苓、白术、麦冬、玄参、熟地、当归、荆芥、防风、苍术、麦芽、甘草,治疗由颅脑外伤、肿瘤、炎症、脑血管病、变性、中毒、以及内科某些疾病等引起的瘫痪,效果显著。CN104940314A一种治疗瘫痪的中药组合物,原料药物组成:桑叶30-35份、竹叶30-35份、大青叶30-35份,具有降气化痰、断痰丝、化顽痰,清肺气、降肺火,通调水道、祛痰散结之功用。这三个专利配方对部分瘫痪均应有一定疗效,但由于配方的局限性,对由复杂多因素引起的瘫痪患者的适用性较差,特别因中风、风湿、类风湿、脑瘫等复杂病因引起的瘫痪可能无能为力或收效甚微,市场急需一种对各类复杂病因引起的瘫痪有治疗实效的药品,以帮助患者站立起来、开口说话、恢复身体各项生理功能、正常独立生活和工作。遗憾的是,目前还没有一种具有治疗中风瘫痪综合功效的技术方案及产品。
发明内容:本发明的目的就是利用纯中草药(草本),运用中医辨证机理,结合中风瘫痪及其他原因引起的瘫痪患者复杂的生理、病理状况,科学配伍组方,确定创造性的技术方案和制备方法,开发出崭新的对各类原因引起的瘫痪具有综合治疗功效的中成药,以满足瘫痪患者治病救命所急需;同时达到对各类患者体质具有广泛的适用性、长期服用安全无副作用的目标。
具体的技术方案由原料组成、组份配比来体现,本发明所涉及的一种治疗中风瘫痪的中成药及其制备方法,原料组成及组份配比如下:山枣皮(10-100)、柴胡(10-80)、紫草(15-100)、清风藤(15-90)、防风(10-80)、白芍(15-100)、青皮(10-60)、茵陈(15-100)、鸡血藤(10-80)、天南星(10-80)、五加皮(15-70)、木香(5-50)、粉防已(10-60)、怀牛膝(15-100)、制半夏(5-50)、玄参(15-90)、厚朴(15-86)、白花蛇舌草(20-100)、桑枝(15-95)、天竺黄(15-95)、龟甲(15-100)、人参(10-60)、龙胆草(10-80)、珍珠母(10-60)、全瓜蒌(15-80)、鳖甲(10-75)、黄芪(20-150)、穿山甲(5-60)、石决明(15-60)、石菖蒲(15-80)、五味子(10-80)、当归(15-80)、白花蛇(3-20条)、龙骨(15-60)、冰片(8-50)、地黄(20-100)、附子(10-90)、蜈蚣(5-30条)、牡蛎(15-80)、远志(10-50)、杜仲(15-80)、淫羊藿(10-80)、全蝎(10-60)、天麻(10-100)、合欢皮(10-80)、木瓜(10-75)、菟丝子(15-105)、水蛭(10-50)、钩藤(15-90)、海浮石(10-80)、白术(15-80)、补骨脂(10-100)、川芎(15-85)、秦艽(10-75)、青礞石(10-90)、茯苓(10-80)、制川乌(5-30)、桃仁(10-80)、葛根(15-100)、代赭石(10-80)、大红枣(10-50)、栀子(18-100)、丹参(15-80)、麻黄(10-55)、山慈菇(5-65)、神曲(10-70)、黄芩(15-100)、赤芍(15-90)、桂枝(15-85)、海蛤粉(15-75)、炙甘草(10-70)、牡丹皮(10-100)、络石藤(15-100)、藁本(10-80)、白芥子(10-60)、枳实(10-70)、知母(15-100)、伸筋草(15-100)、干姜(10-80)、生大黄(15-65)、香附(15-80)、郁金(10-80)、威灵仙(10-70)、羌活(15-70)、芒硝(10-60)、川楝子(10-65)、黄柏(15-80)、豨签草(10-90)、独活(15-85)、泽泻(10-80)、刘寄奴(15-90)、大血藤(10-70)、麝香(0.1-15)组成,辅料有蜂蜜、糊精、米胎。
其制备方法为(蜜丸):将上述配方中的所有原料(不含辅料)清选干净---粉碎2或3次并过筛(200-300目)---混匀---加入炼蜜、米胎、糊精---制成面团并用制丸机制丸---干燥杀菌-分装---检验-入库。
本发明的有益效果,是由配方所选中草药(草本)原料、组份配比及其制备方法予以体现的,具体有益效果包括:治疗中风瘫痪、脑瘫、癫狂、癫痫、高血压、头痛眩晕、颈腰椎骨质增生、肝炎;具有祛风舒筋、滋补肝肾、祛痰渗湿、活血化瘀、大补气血、解痉除抽、降压除栓、通便排毒、清热解毒、补气健脾、理气解郁等功效;由于配方是对心肝脾肺肾及全身进行综合调理,也适用于因风湿、类风湿引起的风湿关节炎、风湿心脏病等慢性疑难重病。
通过以上的中草药(草本)群组原料配伍,对患者全身五脏六腑进行***综合调理,实现阴阳平衡、寒热平衡、祛风除湿、舒筋活血、扶正固本、攻补结合、缩小或避免患者体质个体差异性反应,增强本发明所涉及的中成药治疗各类瘫痪等慢性疑难重病的广泛适用性和有效性。由于配伍的科学独创性,选用原料的低毒性,确保了患者长期服用的安全性。
具体实施方式,有三个方面:一是按上述蜜丸的制备方法制成的中成药丸剂,除吞咽困难的患者外具有广泛的适用性;二是生产成中成药粉剂,适用于肠胃仍较好的患者及吞咽困难的患者。优选实施方式是生产成蜜丸,其次是生产成粉剂。

Claims (4)

1.一种治疗中风瘫痪的中成药及其制备方法,其特征在于它是由下述配方及重量配比的原料及辅料组成:山枣皮(10-100)、柴胡(10-80)、紫草(15-100)、清风藤(15-90)、防风(10-80)、白芍(15-100)、青皮(10-60)、茵陈(15-100)、鸡血藤(10-80)、天南星(10-80)、五加皮(15-70)、木香(5-50)、粉防已(10-60)、怀牛膝(15-100)、制半夏(5-50)、玄参(15-90)、厚朴(15-86)、白花蛇舌草(20-100)、桑枝(15-95)、天竺黄(15-95)、龟甲(15-100)、人参(10-60)、龙胆草(10-80)、珍珠母(10-60)、全瓜蒌(15-80)、鳖甲(10-75)、黄芪(20-150)、穿山甲(5-60)、石决明(15-60)、石菖蒲(15-80)、五味子(10-80)、当归(15-80)、白花蛇(3-20条)、龙骨(15-60)、冰片(8-50)、地黄(20-100)、附子(10-90)、蜈蚣(5-30条)、牡蛎(15-80)、远志(10-50)、杜仲(15-80)、淫羊藿(10-80)、全蝎(10-60)、天麻(10-100)、合欢皮(10-80)、木瓜(10-75)、菟丝子(15-105)、水蛭(10-50)、钩藤(15-90)、海浮石(10-80)、白术(15-80)、补骨脂(10-100)、川芎(15-85)、秦艽(10-75)、青礞石(10-90)、茯苓(10-80)、制川乌(5-30)、桃仁(10-80)、葛根(15-100)、代赭石(10-80)、大红枣(10-50)、栀子(18-100)、丹参(15-80)、麻黄(10-55)、山慈菇(5-65)、神曲(10-70)、黄芩(15-100)、赤芍(15-90)、桂枝(15-85)、海蛤粉(15-75)、炙甘草(10-70)、牡丹皮(10-100)、络石藤(15-100)、藁本(10-80)、白芥子(10-60)、枳实(10-70)、知母(15-100)、伸筋草(15-100)、干姜(10-80)、生大黄(15-65)、香附(15-80)、郁金(10-80)、威灵仙(10-70)、羌活(15-70)、芒硝(10-60)、川楝子(10-65)、黄柏(15-80)、豨签草(10-90)、独活(15-85)、泽泻(10-80)、刘寄奴(15-90)、大血藤(10-70)、麝香(0.1-15)组成,辅料有蜂蜜、糊精、米胎。
2.如权利要求1所述的治疗中风瘫痪的中成药及其制备方法,其特征在于各原料组成及重量配比为山枣皮(10-100)、柴胡(10-80)、紫草(15-100)、清风藤(15-90)、防风(10-80)、白芍(15-100)、青皮(10-60)、茵陈(15-100)、鸡血藤(10-80)、天南星(10-80)、五加皮(15-70)、木香(5-50)、粉防已(10-60)、怀牛膝(15-100)、制半夏(5-50)、玄参(15-90)、厚朴(15-86)、白花蛇舌草(20-100)、桑枝(15-95)、天竺黄(15-95)、龟甲(15-100)、人参(10-60)、龙胆草(10-80)、珍珠母(10-60)、全瓜蒌(15-80)、鳖甲(10-75)、黄芪(20-150)、穿山甲(5-60)、石决明(15-60)、石菖蒲(15-80)、五味子(10-80)、当归(15-80)、白花蛇(3-20条)、龙骨(15-60)、冰片(8-50)、地黄(20-100)、附子(10-90)、蜈蚣(5-30条)、牡蛎(15-80)、远志(10-50)、杜仲(15-80)、淫羊藿(10-80)、全蝎(10-60)、天麻(10-100)、合欢皮(10-80)、木瓜(10-75)、菟丝子(15-105)、水蛭(10-50)、钩藤(15-90)、海浮石(10-80)、白术(15-80)、补骨脂(10-100)、川芎(15-85)、秦艽(10-75)、青礞石(10-90)、茯苓(10-80)、制川乌(5-30)、桃仁(10-80)、葛根(15-100)、代赭石(10-80)、大红枣(10-50)、栀子(18-100)、丹参(15-80)、麻黄(10-55)、山慈菇(5-65)、神曲(10-70)、黄芩(15-100)、赤芍(15-90)、桂枝(15-85)、海蛤粉(15-75)、炙甘草(10-70)、牡丹皮(10-100)、络石藤(15-100)、藁本(10-80)、白芥子(10-60)、枳实(10-70)、知母(15-100)、伸筋草(15-100)、干姜(10-80)、生大黄(15-65)、香附(15-80)、郁金(10-80)、威灵仙(10-70)、羌活(15-70)、芒硝(10-60)、川楝子(10-65)、黄柏(15-80)、豨签草(10-90)、独活(15-85)、泽泻(10-80)、刘寄奴(15-90)、大血藤(10-70),辅料有蜂蜜、糊精、米胎。
3.如权利要求1所述的治疗中风瘫痪的中成药及其制备方法,其特征在于各原料组成及重量配比为柴胡(10-80)、清风藤(15-90)、防风(10-80)、白芍(15-100)、青皮(10-60)、茵陈(15-100)、鸡血藤(10-80)、天南星(10-80)、五加皮(15-70)、木香(5-50)、粉防已(10-60)、怀牛膝(15-100)、制半夏(5-50)、厚朴(15-86)、白花蛇舌草(20-100)、桑枝(15-95)、天竺黄(15-95)、龟甲(15-100)、人参(10-60)、龙胆草(10-80)、珍珠母(10-60)、全瓜蒌(15-80)、鳖甲(10-75)、黄芪(20-150)、石决明(15-60)、石菖蒲(15-80)、五味子(10-80)、当归(15-80)、白花蛇(3-20条)、龙骨(15-60)、冰片(8-50)、地黄(20-100)、附子(10-90)、蜈蚣(5-30条)、牡蛎(15-80)、远志(10-50)、杜仲(15-80)、淫羊藿(10-80)、全蝎(10-60)、天麻(10-100)、合欢皮(10-80)、木瓜(10-75)、菟丝子(15-105)、钩藤(15-90)、海浮石(10-80)、白术(15-80)、补骨脂(10-100)、川芎(15-85)、秦艽(10-75)、青礞石(10-90)、茯苓(10-80)、制川乌(5-30)、桃仁(10-80)、葛根(15-100)、代赭石(10-80)、大红枣(10-50)、栀子(18-100)、丹参(15-80)、麻黄(10-55)、山慈菇(5-65)、神曲(10-70)、黄芩(15-100)、赤芍(15-90)、桂枝(15-85)、海蛤粉(15-75)、炙甘草(10-70)、牡丹皮(10-100)、络石藤(15-100)、藁本(10-80)、白芥子(10-60)、枳实(10-70)、知母(15-100)、伸筋草(15-100)、干姜(10-80)、生大黄(15-65)、香附(15-80)、郁金(10-80)、威灵仙(10-70)、羌活(15-70)、芒硝(10-60)、川楝子(10-65)、黄柏(15-80)、豨签草(10-90)、独活(15-85)、泽泻(10-80)、刘寄奴(15-90)、大血藤(10-70)麝香(0.1-15),辅料有蜂蜜、糊精、米胎。
4.如权利要求1所述的治疗中风瘫痪的中成药及其制备方法,其特征在于各原料组成及重量配比为山枣皮(10-100)、柴胡(10-80)、紫草(15-100)、清风藤(15-90)、防风(10-80)、白芍(15-100)、青皮(10-60)、茵陈(15-100)、鸡血藤(10-80)、天南星(10-80)、五加皮(15-70)、木香(5-50)、粉防已(10-60)、怀牛膝(15-100)、制半夏(5-50)、白花蛇舌草(20-100)、桑枝(15-95)、天竺黄(15-95)、人参(10-60)、龙胆草(10-80)、珍珠母(10-60)、全瓜蒌(15-80)、黄芪(20-150)、石决明(15-60)、石菖蒲(15-80)、五味子(10-80)、当归(15-80)、白花蛇(3-20条)、龙骨(15-60)、冰片(8-50)、地黄(20-100)、附子(10-90)、蜈蚣(5-30条)、牡蛎(15-80)、远志(10-50)、杜仲(15-80)、淫羊藿(10-80)、全蝎(10-60)、合欢皮(10-80)、木瓜(10-75)、菟丝子(15-105)、钩藤(15-90)、海浮石(10-80)、白术(15-80)、补骨脂(10-100)、川芎(15-85)、秦艽(10-75)、青礞石(10-90)、茯苓(10-80)、制川乌(5-30)、桃仁(10-80)、葛根(15-100)、代赭石(10-80)、丹参(15-80)、麻黄(10-55)、山慈菇(5-65)、神曲(10-70)、黄芩(15-100)、赤芍(15-90)、桂枝(15-85)、海蛤粉(15-75)、炙甘草(10-70)、牡丹皮(10-100)、络石藤(15-100)、藁本(10-80)、白芥子(10-60)、枳实(10-70)、知母(15-100)、伸筋草(15-100)、干姜(10-80)、生大黄(15-65)、香附(15-80)、郁金(10-80)、威灵仙(10-70)、羌活(15-70)、芒硝(10-60)、川楝子(10-65)、黄柏(15-80)、稀签草(10-90)、独活(15-85)、泽泻(10-80)、刘寄奴(15-90)、大血藤(10-70)、麝香(0.1-15)组成,辅料有蜂蜜、糊精、米胎。
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