CN105749261B - 复方盐酸溶菌酶***片及其制备方法 - Google Patents
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- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
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- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
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- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
组分 | 01 | 02 | 03 |
盐酸溶菌酶 | 3.0 | 3.0 | 3.0 |
蔗糖 | 30 | 30 | 30 |
甘露醇 | 3.0 | 6.0 | 10 |
乳糖 | 10 | 10 | 10 |
硬脂酸镁 | 0.2 | 0.2 | 0.2 |
纯化水 | 30 | 30 | 30 |
原辅料 | 01 | 02 | 03 |
性状 | 片面不光洁 | 片面光洁 | 片面光洁 |
脆碎度 | ≤1% | ≤1% | ≤1% |
融变时限(min) | 13 | 6 | 4 |
备注 | 融变时间长 | 融变时间较长 | 融变时间较好 |
组分 | 04 | 05 | 06 | 07 |
盐酸溶菌酶 | 3.0 | 3.5 | 4.0 | 5.0 |
蔗糖 | 30 | 35 | 45 | 50 |
甘露醇 | 10 | 14 | 16 | 18 |
乳糖 | 10 | 14 | 16 | 18 |
硬脂酸镁 | 0.2 | 0.4 | 0.6 | 0.8 |
纯化水 | 30 | 35 | 40 | 50 |
原辅料 | 04 | 05 | 06 | 07 |
性状 | 片面光洁 | 片面光洁 | 片面光洁 | 片面光洁 |
脆碎度 | ≤1% | ≤1% | ≤1% | ≤1% |
融变时限(min) | 4 | 4 | 3 | 3 |
备注 | 融变时间较好 | 融变时间较好 | 融变时间较好 | 融变时间较好 |
Claims (6)
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CN201610309450.8A CN105749261B (zh) | 2016-05-11 | 2016-05-11 | 复方盐酸溶菌酶***片及其制备方法 |
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CN201610309450.8A CN105749261B (zh) | 2016-05-11 | 2016-05-11 | 复方盐酸溶菌酶***片及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN105749261A CN105749261A (zh) | 2016-07-13 |
CN105749261B true CN105749261B (zh) | 2020-07-17 |
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CN (1) | CN105749261B (zh) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1663610A (zh) * | 2004-03-01 | 2005-09-07 | 孙明杰 | 溶菌酶新制剂 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU224320B1 (hu) * | 2001-05-23 | 2005-07-28 | József Szabó | Lizozimot vagy lizozim-hidrokloridot tartalmazó hüvelyfertőtlenítő kúp |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1663610A (zh) * | 2004-03-01 | 2005-09-07 | 孙明杰 | 溶菌酶新制剂 |
Non-Patent Citations (1)
Title |
---|
蔗糖凝胶治疗细菌性***病Ⅱ期临床试验研究;肖冰冰等;《北京大学学报( 医学版)》;20101231;第42卷(第6期);摘要,第750页讨论3.1 * |
Also Published As
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