CN105727117A - Medicine for treating prostatic hyperplasia and preparation method thereof - Google Patents
Medicine for treating prostatic hyperplasia and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a medicine for treating prostatic hyperplasia and a preparation method thereof.The medicine is prepared from, by weight, 9-18 parts of cornus officinalis, 20-30 parts of prepared rehmannia roots, 3-10 parts of testiset penis phocae, 9-16 parts of Chinese yam, 4-10 parts of pangolin, 3-6 parts of eupolyphaga, 10-20 parts of radix angelica sinensis, 1-5 parts of leeches, 5-16 parts of raspberry, 5-16 parts of cherokee rose fruit, 9-20 parts of sharpleaf galangal fruit, 8-20 parts of combined spicebush roots, 5-13 parts of cortex moutan, 6-15 parts of rhizoma alismatis and 5-15 parts of poria cocos.The medicine raw materials are dried and broken into medicine powder, the medicine powder is mixed with auxiliary materials, and pelleting and drying are performed.The medicine for treating prostatic hyperplasia can reinforce the kidneys to replenish essence, regulate qi and promote urination, break stagnated blood and remove stasis, treats both the current problems and root causes, hits pathogenesis and is remarkable in prostatic hyperplasia treating effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine treating prostatic hyperplasia and preparation method thereof.
Background technology
Prostate size is with change of age, and minimum during child, glandular tissue is undeveloped, is mainly made up of smooth muscle and connective tissue；Period of maturation prostate sharp increase, particularly glandular tissue；The most gradually degenerating to old age, glandular tissue atrophy, it is then pathological phenomenon that old people produces prostatic hyperplasia.Prostatic hyperplasia cardinal symptom shows themselves in that dysuria, frequent micturition, urinary incontinence, urine are unable etc., needs urethral catheterization or operative treatment time serious, and patient is the most painful, has a strong impact on physical and mental health and the quality of life of patient.At present, the western medicine Treatment of Benign Prostatic Hyperplasia time is long, it is impossible to radical cure, side effect is bigger, treatment by Chinese herbs DeGrain.
Chinese patent CN101791349B discloses one and treats prostatitic Chinese medicine preparation and preparation method thereof, its primary raw material medicine and weight proportion: Radix Rehmanniae Preparata 12-60 part, Poria 8-45 part, Fructus Foeniculi 8-45 part, Fructus Corni 8-45 part, Hylarana guentheri 6-35 part, Radix Achyranthis Bidentatae 8-45 part；Preparation method: 1, medical material is cleaned, and little mattress perfume (or spice) salt system, Hirudo is Hirudo (processed), and Radix Rehmanniae Preparata is for cooking Radix Rehmanniae, and Radix Aconiti Lateralis Preparata is Radix Aconiti Lateralis Preparata；2, all medicinal material dryings, pulverize as 100-200 mesh medicated powder, mix homogeneously, soak secondary and decoct and leach；Twice filtrate being merged, obtain activity extract, stir, being condensed into density is 1.30-1.35 paste, and drying pulverizing is 100-200 mesh medicated powder, obtains powder；3, add adjuvant, make capsule, tablet etc..To prostatitis, Treatment of Benign Prostatic Hyperplasia effect substantially, stably；Treatment cycle is short, relapse rate is low；And energy health invigorating, resisting fatigue, slow down aging.Chinese patent CN101732660B discloses a kind of Chinese medicine preparation treating prostatosis, the medicament being made up of 70 taste raw medicinal materials such as Radix Ginseng, Colla cornus cervi, Radix Morindae Officinalis, Rhizoma Curculiginises: described medicament is oral liquid, powder, capsule, electuary, tablet or pill.Its preparation method: crude drug is made as aqueous extract by (1), (2) aqueous extract is made as oral liquid, and aqueous extract is dried, pulverizes, sieves by (3), extracting screen underflow, for extract drugs powder, (4) use extract drugs powder film-making, granule, pill, electuary or capsule.The crude drug that this patent uses is conventional Chinese medicine, and cost of manufacture is low, substantially has no side effect.The medicine of this patent has preferable curative effect to prostatitis, prostatic hyperplasia, hypertrophy, obvious to carcinoma of prostate effect.But, these patent effects are the most inconspicuous, relatively costly.
Summary of the invention
For overcoming drawbacks described above, it is an object of the invention to provide a kind of medicine treating prostatic hyperplasia, formula is reasonable, and therapeutic effect is notable.
Another object of the present invention also resides in the preparation method providing a kind of medicine treating prostatic hyperplasia, and preparation method is simple, and raw material sources are extensive, with low cost.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 9-18 part, Radix Rehmanniae Preparata 20-30 part, Testis et penis callorhini 3-10 part, Rhizoma Dioscoreae 9-16 part, Squama Manis 4-10 part, eupolyphaga 3-6 part, Radix Angelicae Sinensis 10-20 part, Hirudo 1-5 part, Fructus Rubi 5-16 part, Fructus Rosae Laevigatae 5-16 part, Fructus Alpiniae Oxyphyllae 9-20 part, Radix Linderae 8-20 part, Cortex Moutan 5-13 part, Rhizoma Alismatis 6-15 part and Poria 5-15 part.
According to the medicine of above-mentioned treatment prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 9-12 part, Radix Rehmanniae Preparata 20-24 part, Testis et penis callorhini 3-6 part, Rhizoma Dioscoreae 9-12 part, Squama Manis 4-6 part, eupolyphaga 3-4 part, Radix Angelicae Sinensis 10-12 part, Hirudo 1-3 part, Fructus Rubi 5-9 part, Fructus Rosae Laevigatae 5-9 part, Fructus Alpiniae Oxyphyllae 9-12 part, Radix Linderae 8-12 part, Cortex Moutan 5-9 part, Rhizoma Alismatis 6-9 part and Poria 5-9 part.
According to the medicine of above-mentioned treatment prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 12 parts, Radix Rehmanniae Preparata 24 parts, Testis et penis callorhini 6 parts, Rhizoma Dioscoreae 12 parts, Squama Manis 6 parts, eupolyphaga 4 parts, Radix Angelicae Sinensis 12 parts, Hirudo 3 parts, Fructus Rubi 9 parts, Fructus Rosae Laevigatae 9 parts, Fructus Alpiniae Oxyphyllae 12 parts, the Radix Linderae 12 parts, Cortex Moutan 9 parts, Rhizoma Alismatis 9 parts and 9 parts of Poria.
Various crude drug are dried, are broken into medicated powder, then mix with adjuvant by the preparation method of the medicine of a kind of above-mentioned treatment prostatic hyperplasia, and pill is dried, to obtain final product.
The preparation method of the medicine according to above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) various crude drug are dried, are broken into medicated powder, standby；
(2) in 580-610 part corn starch, add 1800-2200 part water, mix homogeneously, heat 10-20 min, obtain cornmeal mush；
(3) the medicated powder 1800-2200 part taking step (1) adds in step (2) cornmeal mush, stirs 5-10 min, pill, is dried, to obtain final product.
The preparation method of the medicine according to above-mentioned treatment prostatic hyperplasia, step (1) medicated powder is crossed 80-120 mesh sieve and is processed.
The present invention treats the instructions of taking of the medicine of prostatic hyperplasia, three times a day, each 20-30 ball, every ball 0.2-0.25 g, within one month, is a course for the treatment of.
The pharmacological action of the various crude drug of the present invention:
Fructus Corni, sour, puckery, tepor, return liver, kidney channel；Liver and kidney tonifying, essence astringing and desertion stemming, for vertigo and tinnitus, soreness of waist and knee joint, sun passes out semen repeatly, enuresis frequent micturition. and bleeding not during menses, profuse sweating collapses, and interior-heat is quenched one's thirst.
Radix Rehmanniae Preparata, sweet, tepor, return liver, kidney channel；Nourishing YIN and supplementing blood, benefit essence fills out marrow, and for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat passes out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizziness, tinnitus, early whitening of beard and hair.
Testis et penis callorhini, salty in the mouth；Property heat, return liver, kidney channel；Warming the kidney tonifying YANG, benefit essence is mended marrow, is controlled deficient impairment caused by overstrain；Sexual impotence essence declines；Premature ejaculation；Waist knee flaccidity；Trusted subordinate's pain.
Rhizoma Dioscoreae, sweet, flat, return spleen, lung, kidney channel；Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission, and for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung breathes with cough, and emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating, for insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Squama Manis, salty, it is slightly cold, returns liver, stomach warp；Stimulate the menstrual flow stimulating milk secretion, detumescence and apocenosis, search wind and removing obstruction in channels, for amenorrhea abdominal mass, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Eupolyphaga, salty, cold, slightly poisonous, return Liver Channel；Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones, for injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Radix Angelicae Sinensis, sweet, acrid, warm, return liver, the heart, spleen channel；Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation, for blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Hirudo, salty, bitter, flat, slightly poisonous, return Liver Channel；Removing blood stasis, removing blood stasis, stimulates the menstrual flow, for abdominal mass mass in the abdomen, blood stasis amenorrhea, injury from falling down.
Fructus Rubi, sweet, sour, temperature, return kidney, bladder warp；Kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination, for enuresis due to deficiency of the kidney, frequent micturition, impotence and premature ejaculation, emission and spermatorrhea.
Fructus Rosae Laevigatae, sour, sweet, puckery, flat, return kidney, bladder, large intestine channel；Controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents, for emission and spermatorrhea, enuresis urine is on the point of, bleeding not during menses, chronic diarrhea chronic dysentery.
Fructus Alpiniae Oxyphyllae, acrid in the mouth, warm in nature, return spleen, kidney channel；Warming spleen and stopping diarrha take the photograph saliva, warming the kidney controlling nocturnal emission with astringent drugs reducing urination, have loose bowels for spleen-cold syndrome, cold type of pain in abdomen, the many salivas of mouth, enuresis due to deficiency of the kidney, frequent micturition, nebulousurine of passing out semen.
The Radix Linderae, pungent, yearningly, return lung, spleen, kidney, bladder warp；Pleasant pain relieving, warming kidney for dispelling cold, for chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.
Cortex Moutan, bitter, pungent, it is slightly cold, GUIXIN, liver, kidney channel；Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, for maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Rhizoma Alismatis, sweet, cold, return kidney, bladder warp, diuresis, clearing away damp-heat；For dysuria. edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipidemia.
Poria, sweet, light, flat, GUIXIN, lung, spleen, kidney channel；Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, for edema oliguria. and phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Medicine each crude drug compatibility that the present invention treats prostatic hyperplasia is reasonable, and Fructus Corni, Radix Rehmanniae Preparata, Testis et penis callorhini and Rhizoma Dioscoreae are monarch drug, Fructus Corni liver and kidney tonifying, essence astringing and desertion stemming, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, benefit essence fills out marrow, Testis et penis callorhini warming the kidney tonifying YANG, benefit essence mends marrow, Rhizoma Dioscoreae spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission, four taste crude drug share, tonifying kidney-yin, replenishing essence marrow；Squama Manis, eupolyphaga, Radix Angelicae Sinensis and Hirudo are share as ministerial drug, and Squama Manis stimulates the menstrual flow stimulating milk secretion, and detumescence and apocenosis searches wind and removing obstruction in channels, eupolyphaga removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones, Chinese angelica blood supplementing invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, Hirudo removing blood stasis, removing blood stasis, stimulates the menstrual flow, and four taste crude drug share, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving；Fructus Rubi, Fructus Rosae Laevigatae, Fructus Alpiniae Oxyphyllae and the Radix Linderae are adjuvant drug, Fructus Rubi kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination, Fructus Rosae Laevigatae controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents, Fructus Alpiniae Oxyphyllae is warming spleen and stopping diarrha takes the photograph saliva, warming the kidney controlling nocturnal emission with astringent drugs reducing urination, the pleasant pain relieving of the Radix Linderae, warming kidney for dispelling cold, four taste crude drug share, controlling nocturnal emission with astringent drugs reducing urination, astringent therapy of regulating the flow of vital energy；Cortex Moutan, Rhizoma Alismatis and Poria are for making medicine, and Cortex Moutan clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, Rhizoma Alismatis diuresis, clearing away damp-heat, Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, three taste crude drug share, and coordinating the actions of various ingredients in a prescription has been reseeded and let out, made not stagnant.Above crude drug share, and plays kidney tonifying, essence replenishing, supplementing QI to induce diuresis, removing blood stasis eliminating stagnation, treating both the principal and secondary aspects of a disease altogether, and hit pathogenesis, and treatment prostatic hyperplasia effect is notable.
The positive beneficial effect of the present invention:
1. prostatic hyperplasia because of pathogenesis is: with nephrons virtual loss, qi depression to blood stasis causes ureteral obstruction, the present invention treats the medicine kidney tonifying, essence replenishing of prostatic hyperplasia, supplementing QI to induce diuresis, removing blood stasis eliminating stagnation, treating both the principal and secondary aspects of a disease, hit pathogenesis, cure rate is up to 82%, and total effective rate is up to 95%, and treatment prostatic hyperplasia effect is notable.
2. the present invention treat prostatic hyperplasia medicine use corn starch as adjuvant, corn starch adhesive is good, and pelletization is effective；Preparation method of the present invention is simple, omits and decocts step, and raw material sources are extensive, with low cost.
Detailed description of the invention
Below in conjunction with some detailed description of the invention, the present invention is further described.
Embodiment 1
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 9 parts, Radix Rehmanniae Preparata 20 parts, Testis et penis callorhini 3 parts, Rhizoma Dioscoreae 9 parts, Squama Manis 4 parts, eupolyphaga 3 parts, Radix Angelicae Sinensis 10 parts, Hirudo 1 part, Fructus Rubi 5 parts, Fructus Rosae Laevigatae 5 parts, Fructus Alpiniae Oxyphyllae 9 parts, the Radix Linderae 8 parts, Cortex Moutan 5 parts, Rhizoma Alismatis 6 parts and 5 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 80 mesh sieves, standby；
(2) in 580 parts of corn starchs, add 2200 parts of water, mix homogeneously, heat 20 min, obtain cornmeal mush；
(3) 2000 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 10 min, pill, every ball 0.25 g, is dried, to obtain final product.
Embodiment 2
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 11 parts, Radix Rehmanniae Preparata 22 parts, Testis et penis callorhini 4 parts, Rhizoma Dioscoreae 10 parts, Squama Manis 5 parts, eupolyphaga 3.2 parts, Radix Angelicae Sinensis 11 parts, Hirudo 2 parts, Fructus Rubi 6 parts, Fructus Rosae Laevigatae 8 parts, Fructus Alpiniae Oxyphyllae 10 parts, the Radix Linderae 9 parts, Cortex Moutan 7 parts, Rhizoma Alismatis 8 parts and 6 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 100 mesh sieves, standby；
(2) in 600 parts of corn starchs, add 1800 parts of water, mix homogeneously, heat 15 min, obtain cornmeal mush；
(3) 1800 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 5 min, pill, every ball 0.2 g, is dried, to obtain final product.
Embodiment 3
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 12 parts, Radix Rehmanniae Preparata 24 parts, Testis et penis callorhini 6 parts, Rhizoma Dioscoreae 12 parts, Squama Manis 6 parts, eupolyphaga 4 parts, Radix Angelicae Sinensis 12 parts, Hirudo 3 parts, Fructus Rubi 9 parts, Fructus Rosae Laevigatae 9 parts, Fructus Alpiniae Oxyphyllae 12 parts, the Radix Linderae 12 parts, Cortex Moutan 9 parts, Rhizoma Alismatis 9 parts and 9 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 100 mesh sieves, standby；
(2) in 600 parts of corn starchs, add 2000 parts of water, mix homogeneously, heat 15 min, obtain cornmeal mush；
(3) 2000 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 8 min, pill, every ball 0.2 g, is dried, to obtain final product.
Embodiment 4
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 12 parts, Radix Rehmanniae Preparata 24 parts, Testis et penis callorhini 6 parts, Rhizoma Dioscoreae 12 parts, Squama Manis 6 parts, eupolyphaga 4 parts, Radix Angelicae Sinensis 12 parts, Hirudo 3 parts, Fructus Rubi 9 parts, Fructus Rosae Laevigatae 9 parts, Fructus Alpiniae Oxyphyllae 12 parts, the Radix Linderae 12 parts, Cortex Moutan 9 parts, Rhizoma Alismatis 9 parts, 9 parts of Poria, Rhizoma Sparganii 12 parts and Rhizoma Curcumae 12 parts.
Rhizoma Sparganii, pungent, bitter, flat, return liver, spleen channel；Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, for trace mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.Rhizoma Curcumae, pungent, bitter, temperature, return liver, spleen channel；Circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving, for abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain；Early cervical carcinoma, two taste crude drug join in the formula of the medicine that the present invention treats prostatic hyperplasia, assist a ruler in governing a country monarch drug, vital energy regualting and blood circulation-promoting, further enhancing the therapeutic effect that the present invention treats the medicine of prostatic hyperplasia.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 120 mesh sieves, standby；
(2) in 590 parts of corn starchs, add 2000 parts of water, mix homogeneously, heat 20 min, obtain cornmeal mush；
(3) 2200 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 10 min, pill, every ball 0.2 g, is dried, to obtain final product.
Embodiment 5
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 13 parts, Radix Rehmanniae Preparata 25 parts, Testis et penis callorhini 8 parts, Rhizoma Dioscoreae 15 parts, Squama Manis 8 parts, eupolyphaga 4.5 parts, Radix Angelicae Sinensis 13 parts, Hirudo 3.5 parts, Fructus Rubi 10 parts, Fructus Rosae Laevigatae 10 parts, Fructus Alpiniae Oxyphyllae 15 parts, the Radix Linderae 15 parts, Cortex Moutan 10 parts, Rhizoma Alismatis 12 parts and 11 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 100 mesh sieves, standby；
(2) in 600 parts of corn starchs, add 2000 parts of water, mix homogeneously, heat 20 min, obtain cornmeal mush；
(3) 2000 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 10 min, pill, every ball 0.2 g, is dried, to obtain final product.
Embodiment 6
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 15 parts, Radix Rehmanniae Preparata 26 parts, Testis et penis callorhini 9 parts, Rhizoma Dioscoreae 15 parts, Squama Manis 8 parts, eupolyphaga 4.6 parts, Radix Angelicae Sinensis 15 parts, Hirudo 4 parts, Fructus Rubi 12 parts, Fructus Rosae Laevigatae 11 parts, Fructus Alpiniae Oxyphyllae 17 parts, the Radix Linderae 16 parts, Cortex Moutan 11 parts, Rhizoma Alismatis 13 parts and 12 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 120 mesh sieves, standby；
(2) in 610 parts of corn starchs, add 2200 parts of water, mix homogeneously, heat 20 min, obtain cornmeal mush；
(3) 1800 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 6 min, pill, every ball 0.2 g, is dried, to obtain final product.
Embodiment 7
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 16 parts, Radix Rehmanniae Preparata 28 parts, Testis et penis callorhini 10 parts, Rhizoma Dioscoreae 16 parts, Squama Manis 9 parts, eupolyphaga 5.2 parts, Radix Angelicae Sinensis 16 parts, Hirudo 4.2 parts, Fructus Rubi 15 parts, Fructus Rosae Laevigatae 15 parts, Fructus Alpiniae Oxyphyllae 18 parts, the Radix Linderae 16 parts, Cortex Moutan 12 parts, Rhizoma Alismatis 14 parts and 13 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 100 mesh sieves, standby；
(2) in 605 parts of corn starchs, add 1800 parts of water, mix homogeneously, heat 10 min, obtain cornmeal mush；
(3) 2000 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 10 min, pill, every ball 0.25 g, is dried, to obtain final product.
Embodiment 8
A kind of medicine treating prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 18 parts, Radix Rehmanniae Preparata 30 parts, Testis et penis callorhini 10 parts, Rhizoma Dioscoreae 16 parts, Squama Manis 10 parts, eupolyphaga 6 parts, Radix Angelicae Sinensis 20 parts, Hirudo 5 parts, Fructus Rubi 16 parts, Fructus Rosae Laevigatae 16 parts, Fructus Alpiniae Oxyphyllae 20 parts, the Radix Linderae 20 parts, Cortex Moutan 13 parts, Rhizoma Alismatis 15 parts and 15 parts of Poria.
The preparation method of the medicine of above-mentioned treatment prostatic hyperplasia, comprises the following steps:
(1) above-mentioned various crude drug are dried, are broken into medicated powder, cross 80 mesh sieves, standby；
(2) in 600 parts of corn starchs, add 2000 parts of water, mix homogeneously, heat 15 min, obtain cornmeal mush；
(3) 2000 parts of the medicated powder taking step (1) adds in step (2) cornmeal mush, stirs 10 min, pill, every ball 0.2 g, is dried, to obtain final product.
Clinical case
1, clinical data
1.1 patient data
From 2012 so far, collect 120 example Patients with Prostatic Hyperplasias altogether, minimum 41 years old of age, maximum 81 years old, ＜ 3 examples of 50 years old, 50-60 year 47 examples, 61-70 year 61 examples, 70 years old 9 example of ＞, 61.3 years old mean age；The course of disease is the longest 35 years, the shortest 1 year, average course of disease 17 years.Wherein, I degree increases survivor 36 example, and II degree increases survivor 65 example, and III degree increases survivor 19 example, increases survivor without IV degree..
1.2 diagnostic criteria
The guideline of clinical investigations of benign prostate hyperplasia " new Chinese medicine treatment " promulgated with reference to Ministry of Public Health is diagnostic criteria, and cardinal symptom is: symptom of 1. urinating: urinate hesitate, urinate line carefully, waste time and energy, nocturia frequency；2. ultrasound diagnosis: weight of prostate (prostate volume × 1.05) ＞ 20 g；3. uroflometry: Qmax (Qmax) ＜ 15 mL/s.
Curative effect determinate standard:
Effective: (1) I-PPS scoring≤7, L index≤1, or state of an illness total score reduce by more than 90%；(2) prostate volume is reduced to original less than 60%；(3) Qmax >=18 mL/s；
Effective: (1) I-PPS scoring≤13, L index is that 4-6 is reduced to 2-3, or state of an illness total score reduces by more than 60%；(2) prostate volume is reduced to original less than 80%, and residual urine volume reduces more than 50%；(3) Qmax >=12 mL/s；
Invalid: not up to effective standard.
2, Therapeutic Method
The oral embodiment of the present invention 3 treats the medicine of prostatic hyperplasia, and three times a day, each 30 balls, every ball 0.2 g, one month is a course for the treatment of.
3, clinical test results
The present invention treats the medicine cure rate of prostatic hyperplasia and is up to 82%, and total effective rate is up to 95%.
Model case
High certain, man, 54 years old, District, Xinyang Area, Henan Province city people from Xi County, examine on March 8th, 2015, main suit's frequent micturition, urgent micturition, more than 10 years multi-treatment poor effect, existing nocturia frequency one night 20-30 time, urine front wait, trouble urinating, dribble of urine are not to the utmost.Inspection complexion is normal, and skin is the most dry, dizzy, xerostomia, blurring of vision, and soreness of waist pain, red tongue is dry crackle, less fur, thready and rapid pulse, ultrasound diagnosis prostate 5.5 CM, 4.8 CM, 4.3 CM, residual urine volume 143 milliliters, uroflometry；Maximum uroflow amount≤10 mL/s.Rectum refers to pick up like Ovum Anas domestica +++.It is diagnosed as prostatic hyperplasia, dialectical genus kidney yin deficiency type.Blood, urine, feces are conventional, hepatic and renal function checks the most normal.Use the embodiment of the present invention 3 to treat the medicine of prostatic hyperplasia, three times a day, each 30 balls, withdraw other drug and therapy.After medication 7 days, nocturia number of times is significantly reduced to 6 urine of a night, and other symptom has alleviated, and continues to take 30 days, and symptom all disappears, and adds and had no untoward reaction for clinical cure, period of taking medicine after 2 months, recurrence that so far there are no.
Soup, man, 55 years old, people from Pingqiao District, Xinyang City, Henan Province, examines on August 18th, 2015.Main suit's frequent micturition, urgent micturition, more than 10 years multi-treatment poor effect, existing nocturia frequency one night 6-308 time, the front wait of urine, trouble urinating, urine range are short, and dribble of urine is not to the utmost.Inspection complexion is normal, and skin is normal, dizzy, xerostomia, blurring of vision, and soreness of waist pain, red tongue, tongue body enlargement has crackle, and tongue fur is the thickest, slippery and rapid pulse.Ultrasound diagnosis prostate 5.5CM, 5.1CM, 4.3CM, residual urine volume 70 milliliters, uroflometry；Maximum uroflow amount≤10 mL/s.Rectum refers to pick up like Ovum Anas domestica +++.Being diagnosed as prostatic hyperplasia, dialectical genus phlegm-damp becomes silted up and hinders, kidney yin deficiency type.Blood, urine, feces are conventional, hepatic and renal function checks the most normal.Use the embodiment of the present invention 4 to treat the medicine of prostatic hyperplasia, three times a day, each 30 balls, withdraw other drug and therapy.After medication 10 days, nocturia number of times is significantly reduced to 4 urine of a night, and other symptom has alleviated, and continues to take 30 days, and symptom all disappears, and adds and had no untoward reaction for clinical cure, period of taking medicine after 2 months, recurrence that so far there are no.
Revive certain, man, 54 years old, District, Xinyang Area, Henan Province people from river reach, examine on October 6th, 2013.Main suit's frequent micturition, more than 5 years of urgent micturition multi-treatment poor effect.Existing nocturia frequency one night 5 to 36 times, waiting, urine line attenuates before urine, trouble urinating, dribble of urine are not to the utmost.Inspection complexion is normal, and skin is the most dry, dizzy, xerostomia, blurring of vision, and soreness of waist pain, red tongue is dry crackle, less fur, thready and rapid pulse.Ultrasound diagnosis prostate 5.3CM, 5.0CM, 4.7CM, uroflometry；Maximum uroflow amount≤10 mL/s.Rectum refers to pick up like Ovum Anas domestica +++.Being diagnosed as prostatic hyperplasia, dialectical genus congestion blocks, kidney yin deficiency type.Blood, urine, feces are conventional, hepatic and renal function checks the most normal.Use the embodiment of the present invention 6 to treat the medicine of prostatic hyperplasia, three times a day, each 30 balls, withdraw other drug and therapy.After medication 7 days, nocturia number of times is significantly reduced to 4 urine of a night, and other symptom has alleviated, and continues to take 30 days, and symptom all disappears, and adds and had no untoward reaction for clinical cure, period of taking medicine after 2 months.Drug withdrawal followed up a case by regular visits to stable curative effect after 2 years, had no recurrence.
Zhan, man, 67 years old, Xinyang, river people from Pingqiao District, retired cadre, examines on November 18th, 2014.Main suit's frequent micturition, more than 10 years of urgent micturition multi-treatment poor effect.Existing nocturia frequency one night 8 to 9 times, wait, trouble urinating, dysurea before urine, urge incontinence, dribble of urine is not to the utmost.Inspection complexion is normal, and skin is the most dry, dizzy, xerostomia, blurring of vision, and soreness of waist pain, red tongue is dry crackle, less fur, thready and rapid pulse.Ultrasound diagnosis prostate 5.8CM, 5.2CM, 4.8CM, residual urine volume 134 milliliters, uroflometry；Maximum uroflow amount≤10 mL/s.Rectum refers to pick up like Ovum Anas domestica +++.Being diagnosed as prostatic hyperplasia, dialectical genus congestion blocks, kidney yin deficiency type.Blood, urine, feces are conventional, hepatic and renal function checks the most normal.Use the embodiment of the present invention 2 to treat the medicine of prostatic hyperplasia, three times a day, each 30 balls, withdraw other drug and therapy.After medication 7 days, nocturia number of times is significantly reduced to 7 urine of a night, and other symptom has alleviated, and continues to take 30 days, and symptom all disappears, and adds and had no untoward reaction for clinical cure, period of taking medicine after 2 months.Drug withdrawal followed up a case by regular visits to stable curative effect after 1 year, had no recurrence.
Chen, man, 71 years old, District, Xinyang Area, Henan Province city people from Pingqiao District, examines on May 11st, 2014.Main suit's frequent micturition, more than 10 years of urgent micturition multi-treatment poor effect.Existing nocturia frequency one night 6 to 8 times, waits before urine, trouble urinating, uroflow interruption, dribble of urine is not to the utmost.Inspection complexion is normal, and skin is the most dry, dizzy, and xerostomia is dizzy, blurring of vision, and soreness of waist pain, red tongue is dry crackle, less fur, thready and rapid pulse.Ultrasound diagnosis prostate 5.7CM, 4.8CM, 4.3CM, uroflometry；Maximum uroflow amount≤10 mL/s residual urine volume 96 milliliters.Rectum refers to pick up like Ovum Anas domestica +++.It is diagnosed as prostatic hyperplasia, dialectical genus kidney yin deficiency type.Blood, urine, feces are conventional, hepatic and renal function checks the most normal.Use the embodiment of the present invention 1 to treat the medicine of prostatic hyperplasia, three times a day, each 20 balls, withdraw other drug and therapy.After medication 7 days, nocturia number of times is significantly reduced to 5 urine of a night, and other symptom has alleviated, and continues to take 30 days, and symptom all disappears, and adds and had no untoward reaction for clinical cure, period of taking medicine after 2 months.Drug withdrawal followed up a case by regular visits to stable curative effect after 1 year, had no recurrence.
Claims (6)
1. treating a medicine for prostatic hyperplasia, its crude drug and weight proportion are as follows: Fructus Corni 9-18 part, Radix Rehmanniae Preparata 20-30 part, Testis et penis callorhini 3-10 part, Rhizoma Dioscoreae 9-16 part, Squama Manis 4-10 part, eupolyphaga 3-6 part, Radix Angelicae Sinensis 10-20 part, Hirudo 1-5 part, Fructus Rubi 5-16 part, Fructus Rosae Laevigatae 5-16 part, Fructus Alpiniae Oxyphyllae 9-20 part, Radix Linderae 8-20 part, Cortex Moutan 5-13 part, Rhizoma Alismatis 6-15 part and Poria 5-15 part.
The medicine for the treatment of prostatic hyperplasia the most according to claim 1, it is characterised in that its crude drug and weight proportion are as follows: Fructus Corni 9-12
Part, Radix Rehmanniae Preparata 20-24 part, Testis et penis callorhini 3-6 part, Rhizoma Dioscoreae 9-12 part, Squama Manis 4-6 part, eupolyphaga 3-4 part, Radix Angelicae Sinensis 10-12 part, Hirudo 1-3 part, Fructus Rubi 5-9 part, Fructus Rosae Laevigatae 5-9 part, Fructus Alpiniae Oxyphyllae 9-12 part, Radix Linderae 8-12 part, Cortex Moutan 5-9 part, Rhizoma Alismatis 6-9 part and Poria 5-9 part.
The medicine for the treatment of prostatic hyperplasia the most according to claim 2, it is characterised in that its crude drug and weight proportion are as follows: Fructus Corni 12
Part, Radix Rehmanniae Preparata 24 parts, Testis et penis callorhini 6 parts, Rhizoma Dioscoreae 12 parts, Squama Manis 6 parts, eupolyphaga 4 parts, Radix Angelicae Sinensis 12 parts, Hirudo 3 parts, Fructus Rubi 9 parts, Fructus Rosae Laevigatae 9 parts, Fructus Alpiniae Oxyphyllae 12 parts, the Radix Linderae 12 parts, Cortex Moutan 9 parts, Rhizoma Alismatis 9 parts and 9 parts of Poria.
4. the preparation method of the medicine of the treatment prostatic hyperplasia described in an any one of claim 1-3, it is characterised in that comprise the following steps: various crude drug are dried, be broken into medicated powder, then mix with adjuvant, pill, it is dried, to obtain final product.
The preparation method of the medicine for the treatment of prostatic hyperplasia the most according to claim 4, it is characterised in that comprise the following steps:
(1) various crude drug are dried, are broken into medicated powder, standby；
(2) in 580-610 part corn starch, add 1800-2200 part water, mix homogeneously, heat 10-20 min, obtain cornmeal mush；
(3) the medicated powder 1800-2200 part taking step (1) adds in step (2) cornmeal mush, stirs 5-10
Min, pill, it is dried, to obtain final product.
The preparation method of the medicine for the treatment of prostatic hyperplasia the most according to claim 5, it is characterised in that step (1) medicated powder is crossed 80-120 mesh sieve and processed.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421586A (en) * | 2016-11-11 | 2017-02-22 | 东莞市百替生物科技有限公司 | Traditional Chinese medicine preparation for treating prostatic hyperplasia and preparation method |
| CN107823558A (en) * | 2017-11-15 | 2018-03-23 | 中国医药集团总公司四川抗菌素工业研究所 | A kind of Chinese medicine composition for treating hyperplasia of prostate |
| CN111939047A (en) * | 2020-08-25 | 2020-11-17 | 安徽省库医斯医药用品制造有限公司 | Prostate fumigation treatment chair |
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| CN106421586A (en) * | 2016-11-11 | 2017-02-22 | 东莞市百替生物科技有限公司 | Traditional Chinese medicine preparation for treating prostatic hyperplasia and preparation method |
| CN107823558A (en) * | 2017-11-15 | 2018-03-23 | 中国医药集团总公司四川抗菌素工业研究所 | A kind of Chinese medicine composition for treating hyperplasia of prostate |
| CN111939047A (en) * | 2020-08-25 | 2020-11-17 | 安徽省库医斯医药用品制造有限公司 | Prostate fumigation treatment chair |
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