CN105726396A - Moisturizing fluid and preparation method thereof - Google Patents
Moisturizing fluid and preparation method thereof Download PDFInfo
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- CN105726396A CN105726396A CN201610133004.6A CN201610133004A CN105726396A CN 105726396 A CN105726396 A CN 105726396A CN 201610133004 A CN201610133004 A CN 201610133004A CN 105726396 A CN105726396 A CN 105726396A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses moisturizing fluid. The moisturizing fluid comprises, by weight percentage, 0.03-0.05% of ethylene diamine tetraacetic acid disodium, 5-6% of glycerin, 2.5-3.5% of Jojoba oil, 1-2% of evening primrose oil, 0.02-0.04% of hyaluronic acid, 0.01-0.02% of essence, 0.5-0.8% of camellia extract, 0.3-0.6% of esliptae herba extract, 1.2-1.5% of felwort extract, 0.7-1.1% of taraxacum mongolicum extract and the balance of deionized water. The invention further provides a preparation method of the moisturizing fluid. The moisturizing fluid has the advantages that no ethanol is added into the moisturizing fluid, and the moisturizing fluid is nontoxic, free of side effect, mild and non-irritant, capable of preventing moisture in cuticle from evaporating and reducing, and excellent in skin moisturizing effect.
Description
Technical field
The present invention relates to beauty and skin care field, moisturizing liquid of a kind of replenishing water and preserving moisture and preparation method thereof.
Background technology
Along with the raising of quality of the life, people are more and more higher to the requirement of cosmetics, especially for the cosmetics of replenishing water and preserving moisture class.Moisturizing refers to by application maintenance product and maintains body fluids two kinds of means of balance to maintain skin, the especially water content of face skin epidermal area.Why moisturizing becomes a very important beauty treatment concept, and the moisture being because skin is very easy to run off, and skin lack enough water content will result directly in that skin metabolism is abnormal and old and feeble, wrinkle and mottle etc. occur a series of skin problems.Moisture evaporation is nothing but three reasons: high temperature, dry and strong wind, the moisture of skin is no exception.Therefore, climate characteristic throughout the year contains these factors the most more or less, so being required for moisturizing throughout the year.Three above reason is environmental factors, the problem that skin loss moisture also includes skin itself.Such as, with advancing age, the metabolic capabilities reduction of skin causes hydratability to weaken etc..People recognize that the importance of skin replenishing water and preserving moisture, skin hydropenia can affect skin elasticity, the skin problem such as microgroove, mottle occur.The skin of hydropenia not only overall skinfeel can be substantially reduced, and the metabolism of old cutin often also can make a variation, it can thus be appreciated that moisturizing and moisturizing are critically important for skin.Skin not hydropenia, cells of superficial layer could be transported to skin corium the skin care products spreading upon skin surface effectively.Existing replenishing water and preserving moisture product, it has certain stimulation, life-time service, is unfavorable for skin health skin.It addition, the effect of part replenishing water and preserving moisture product inconspicuous.
Summary of the invention
Moisturizing liquid that it is an object of the invention to provide a kind of replenishing water and preserving moisture and preparation method thereof, with the problem solving to propose in above-mentioned background technology.
For achieving the above object, the present invention provides following technical scheme:
A kind of moisturizing liquid of replenishing water and preserving moisture, being made up of according to the raw material of percentage by weight following: disodiumedetate 0.03-0.05%, glycerol 5-6%, Jojoba oil 2.5-3.5%, Radix Oenotherae erythrosepalae oil 1-2%, hyaluronic acid 0.02-0.04%, essence 0.01-0.02%, Flos Camelliae Japonicae extracting solution 0.5-0.8%, Herba Ecliptae extracting solution 0.3-0.6%, Radix Gentianae extracting solution 1.2-1.5%, Herba Taraxaci extract 0.7-1.1%, surplus is deionized water.
As the further scheme of the present invention: be made up of according to the raw material of percentage by weight following: disodiumedetate 0.04-0.05%, glycerol 5.2-5.8%, Jojoba oil 2.6-3.4%, Radix Oenotherae erythrosepalae oil 1.2-1.7%, hyaluronic acid 0.03-0.04%, essence 0.01-0.02%, Flos Camelliae Japonicae extracting solution 0.6-0.7%, Herba Ecliptae extracting solution 0.4-0.5%, Radix Gentianae extracting solution 1.3-1.4%, Herba Taraxaci extract 0.8-1.0%, surplus is deionized water.
As the present invention further scheme: be made up of according to the raw material of percentage by weight following: disodiumedetate 0.04%, glycerol 5.5%, Jojoba oil 2.9%, Radix Oenotherae erythrosepalae oil 1.5%, hyaluronic acid 0.03%, essence 0.01%, Flos Camelliae Japonicae extracting solution 0.7%, Herba Ecliptae extracting solution 0.5%, Radix Gentianae extracting solution 1.3%, Herba Taraxaci extract 0.9%, deionized water 86.62%.
The preparation method of the moisturizing liquid of described replenishing water and preserving moisture, step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 8-12 times amount deionized water, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 8-12 times amount deionized water, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 15-20 times amount, ultrasonic extraction 40-50min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 50-55 DEG C, insulation 40-50min, stir, be then cooled to 40-45 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
Compared with prior art, the invention has the beneficial effects as follows: the moisturizing liquid of replenishing water and preserving moisture of the present invention does not stimulates without ethanol, no side effects, gentleness, prevent the moisture evaporation in horny layer from reducing, there is excellent replenishing water and preserving moisture, the effect of skin care.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the technical scheme of this patent is described in more detail.
Embodiment 1
The moisturizing liquid of a kind of replenishing water and preserving moisture, is made up of according to the raw material of percentage by weight following: disodiumedetate 0.03%, glycerol 5%, Jojoba oil 2.5%, Radix Oenotherae erythrosepalae oil 1%, hyaluronic acid 0.02%, essence 0.01%, Flos Camelliae Japonicae extracting solution 0.5%, Herba Ecliptae extracting solution 0.3%, Radix Gentianae extracting solution 1.2%, Herba Taraxaci extract 0.7%, deionized water 88.74%.
The preparation method of the moisturizing liquid of replenishing water and preserving moisture described in the present embodiment, step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 8 times amount deionized waters, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 8 times amount deionized waters, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 15 times amount, ultrasonic extraction 40min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 50 DEG C, insulation 40min, stir, be then cooled to 40 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
Embodiment 2
The moisturizing liquid of a kind of replenishing water and preserving moisture, is made up of according to the raw material of percentage by weight following: disodiumedetate 0.05%, glycerol 6%, Jojoba oil 3.5%, Radix Oenotherae erythrosepalae oil 2%, hyaluronic acid 0.04%, essence 0.02%, Flos Camelliae Japonicae extracting solution 0.8%, Herba Ecliptae extracting solution 0.6%, Radix Gentianae extracting solution 1.5%, Herba Taraxaci extract 1.1%, deionized water 84.39%.
The preparation method of the moisturizing liquid of replenishing water and preserving moisture described in the present embodiment, step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 12 times amount deionized waters, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 12 times amount deionized waters, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 20 times amount, ultrasonic extraction 50min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 55 DEG C, insulation 50min, stir, be then cooled to 45 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
Embodiment 3
The moisturizing liquid of a kind of replenishing water and preserving moisture, is made up of according to the raw material of percentage by weight following: disodiumedetate 0.04%, glycerol 5.5%, Jojoba oil 2.9%, Radix Oenotherae erythrosepalae oil 1.5%, hyaluronic acid 0.03%, essence 0.01%, Flos Camelliae Japonicae extracting solution 0.7%, Herba Ecliptae extracting solution 0.5%, Radix Gentianae extracting solution 1.3%, Herba Taraxaci extract 0.9%, deionized water 86.62%.
The preparation method of the moisturizing liquid of replenishing water and preserving moisture described in the present embodiment, step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 10 times amount deionized waters, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 10 times amount deionized waters, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 18 times amount, ultrasonic extraction 45min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 53 DEG C, insulation 45min, stir, be then cooled to 42 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
Embodiment 4
The moisturizing liquid of a kind of replenishing water and preserving moisture, is made up of according to the raw material of percentage by weight following: disodiumedetate 0.04%, glycerol 5%, Jojoba oil 3.5%, Radix Oenotherae erythrosepalae oil 2%, hyaluronic acid 0.04%, essence 0.01%, Flos Camelliae Japonicae extracting solution 0.5%, Herba Ecliptae extracting solution 0.5%, Radix Gentianae extracting solution 1.3%, Herba Taraxaci extract 1%, deionized water 86.11%.
The preparation method of the moisturizing liquid of replenishing water and preserving moisture described in the present embodiment, step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 9 times amount deionized waters, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 12 times amount deionized waters, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 16 times amount, ultrasonic extraction 50min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 54 DEG C, insulation 50min, stir, be then cooled to 43 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
Embodiment 5
The moisturizing liquid of a kind of replenishing water and preserving moisture, is made up of according to the raw material of percentage by weight following: disodiumedetate 0.04%, glycerol 5.5%, Jojoba oil 3.5%, Radix Oenotherae erythrosepalae oil 1%, hyaluronic acid 0.03%, essence 0.02%, Flos Camelliae Japonicae extracting solution 0.5%, Herba Ecliptae extracting solution 0.3%, Radix Gentianae extracting solution 1.4%, Herba Taraxaci extract 0.9%, deionized water 86.81%.
The preparation method of the moisturizing liquid of replenishing water and preserving moisture described in the present embodiment, step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 12 times amount deionized waters, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 12 times amount deionized waters, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 18 times amount, ultrasonic extraction 40min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 55 DEG C, insulation 40min, stir, be then cooled to 42 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
Use display continuously through several not specific users, the moisturizing liquid of replenishing water and preserving moisture of the present invention can the low and deep dry skin of regulations, smear the salubrious non-greasy of Shi Shuirun, for the skin of hydropenia, after coating 12 hours, skin still keep water moisten state;After being used in conjunction 28 days, the low and deep phenomenon of xerosis cutis substantially disappears, and skin water profit elasticity promotes.
The moisturizing liquid of replenishing water and preserving moisture of the present invention does not stimulates without ethanol, no side effects, gentleness, prevents the moisture evaporation in horny layer from reducing, has excellent replenishing water and preserving moisture, the effect of skin care.
Above the better embodiment of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment, in the ken that one skilled in the relevant art is possessed, it is also possible to various changes can be made on the premise of without departing from this patent objective.
Claims (4)
1. the moisturizing liquid of a replenishing water and preserving moisture, it is characterized in that, being made up of according to the raw material of percentage by weight following: disodiumedetate 0.03-0.05%, glycerol 5-6%, Jojoba oil 2.5-3.5%, Radix Oenotherae erythrosepalae oil 1-2%, hyaluronic acid 0.02-0.04%, essence 0.01-0.02%, Flos Camelliae Japonicae extracting solution 0.5-0.8%, Herba Ecliptae extracting solution 0.3-0.6%, Radix Gentianae extracting solution 1.2-1.5%, Herba Taraxaci extract 0.7-1.1%, surplus is deionized water.
The moisturizing liquid of replenishing water and preserving moisture the most according to claim 1, it is characterized in that, being made up of according to the raw material of percentage by weight following: disodiumedetate 0.04-0.05%, glycerol 5.2-5.8%, Jojoba oil 2.6-3.4%, Radix Oenotherae erythrosepalae oil 1.2-1.7%, hyaluronic acid 0.03-0.04%, essence 0.01-0.02%, Flos Camelliae Japonicae extracting solution 0.6-0.7%, Herba Ecliptae extracting solution 0.4-0.5%, Radix Gentianae extracting solution 1.3-1.4%, Herba Taraxaci extract 0.8-1.0%, surplus is deionized water.
The moisturizing liquid of replenishing water and preserving moisture the most according to claim 2, it is characterized in that, be made up of according to the raw material of percentage by weight following: disodiumedetate 0.04%, glycerol 5.5%, Jojoba oil 2.9%, Radix Oenotherae erythrosepalae oil 1.5%, hyaluronic acid 0.03%, essence 0.01%, Flos Camelliae Japonicae extracting solution 0.7%, Herba Ecliptae extracting solution 0.5%, Radix Gentianae extracting solution 1.3%, Herba Taraxaci extract 0.9%, deionized water 86.62%.
4. the preparation method of the moisturizing liquid of the replenishing water and preserving moisture as described in claim 1-3 is arbitrary, it is characterised in that step is as follows:
1) Flos Camelliae Japonicae is weighed, after drying, add 8-12 times amount deionized water, extract 2 times in 60 DEG C of water-baths, each 30 minutes, after filtration, residue is added 8-12 times amount deionized water, extraction 2 times at 80 DEG C, each 20 minutes, extracting solution at merging 60 DEG C and 80 DEG C, filter, concentrate filtrate to 8g/mL, obtain Flos Camelliae Japonicae extracting solution;
2) Herba Ecliptae extracting solution is prepared according to step 1) method;
3) weigh Radix Gentianae, add the ethanol of 15-20 times amount, ultrasonic extraction 40-50min, filter, concentrate filtrate to 10 g/mL, obtain Radix Gentianae extracting solution;
4) Herba Taraxaci extract is prepared according to step 3) method;
5) disodiumedetate, hyaluronic acid, essence and deionized water are weighed, it is heated to 50-55 DEG C, insulation 40-50min, stir, be then cooled to 40-45 DEG C, add glycerol, Jojoba oil and Radix Oenotherae erythrosepalae oil, stir, add Flos Camelliae Japonicae extracting solution, Herba Ecliptae extracting solution, Radix Gentianae extracting solution and Herba Taraxaci extract, stir, obtain the moisturizing liquid of replenishing water and preserving moisture.
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CN107898702A (en) * | 2017-12-19 | 2018-04-13 | 广东德新科技孵化器有限公司 | A kind of dandelion toner containing ossein and preparation method thereof |
CN108619070A (en) * | 2018-07-13 | 2018-10-09 | 洛阳珂玺生物科技有限公司 | A kind of ginseng moisturizing liquid and preparation method thereof |
CN110652479A (en) * | 2019-10-24 | 2020-01-07 | 樊瑞 | Composition with moisturizing and hydrating functions and preparation method thereof |
CN112842981A (en) * | 2021-02-03 | 2021-05-28 | 中南大学湘雅医院 | Whitening and nourishing essence and preparation process thereof |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107898702A (en) * | 2017-12-19 | 2018-04-13 | 广东德新科技孵化器有限公司 | A kind of dandelion toner containing ossein and preparation method thereof |
CN108619070A (en) * | 2018-07-13 | 2018-10-09 | 洛阳珂玺生物科技有限公司 | A kind of ginseng moisturizing liquid and preparation method thereof |
CN110652479A (en) * | 2019-10-24 | 2020-01-07 | 樊瑞 | Composition with moisturizing and hydrating functions and preparation method thereof |
CN112842981A (en) * | 2021-02-03 | 2021-05-28 | 中南大学湘雅医院 | Whitening and nourishing essence and preparation process thereof |
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