CN105724386B - A kind of bactericidal composition of Fluxapyroxad-containsterilization - Google Patents
A kind of bactericidal composition of Fluxapyroxad-containsterilization Download PDFInfo
- Publication number
- CN105724386B CN105724386B CN201610117912.6A CN201610117912A CN105724386B CN 105724386 B CN105724386 B CN 105724386B CN 201610117912 A CN201610117912 A CN 201610117912A CN 105724386 B CN105724386 B CN 105724386B
- Authority
- CN
- China
- Prior art keywords
- fluxapyroxad
- active constituent
- disease
- containsterilization
- bactericidal composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 47
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 18
- SXSGXWCSHSVPGB-UHFFFAOYSA-N fluxapyroxad Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1=CC(F)=C(F)C(F)=C1 SXSGXWCSHSVPGB-UHFFFAOYSA-N 0.000 claims abstract description 86
- 239000005788 Fluxapyroxad Substances 0.000 claims abstract description 84
- 239000000470 constituent Substances 0.000 claims abstract description 56
- 201000010099 disease Diseases 0.000 claims abstract description 55
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 55
- 150000003839 salts Chemical class 0.000 claims abstract description 34
- 230000000694 effects Effects 0.000 claims abstract description 25
- 239000005821 Propamocarb Substances 0.000 claims abstract description 22
- WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 claims abstract description 22
- XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 claims abstract description 20
- 239000005756 Cymoxanil Substances 0.000 claims abstract description 20
- 239000005797 Iprovalicarb Substances 0.000 claims abstract description 20
- NWUWYYSKZYIQAE-ZBFHGGJFSA-N L-(R)-iprovalicarb Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-ZBFHGGJFSA-N 0.000 claims abstract description 20
- 239000005754 Cyazofamid Substances 0.000 claims abstract description 18
- YXKMMRDKEKCERS-UHFFFAOYSA-N cyazofamid Chemical compound CN(C)S(=O)(=O)N1C(C#N)=NC(Cl)=C1C1=CC=C(C)C=C1 YXKMMRDKEKCERS-UHFFFAOYSA-N 0.000 claims abstract description 18
- 241000233679 Peronosporaceae Species 0.000 claims description 30
- 239000000375 suspending agent Substances 0.000 claims description 18
- 239000000839 emulsion Substances 0.000 claims description 12
- 239000003094 microcapsule Substances 0.000 claims description 10
- 239000004563 wettable powder Substances 0.000 claims description 10
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 9
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000000725 suspension Substances 0.000 claims description 6
- 241000582441 Peronospora tabacina Species 0.000 claims description 5
- 208000010801 foot rot Diseases 0.000 claims description 5
- 239000004562 water dispersible granule Substances 0.000 claims description 5
- 239000004615 ingredient Substances 0.000 claims description 3
- 230000002195 synergetic effect Effects 0.000 abstract description 28
- QNBTYORWCCMPQP-JXAWBTAJSA-N (Z)-dimethomorph Chemical compound C1=C(OC)C(OC)=CC=C1C(\C=1C=CC(Cl)=CC=1)=C/C(=O)N1CCOCC1 QNBTYORWCCMPQP-JXAWBTAJSA-N 0.000 abstract description 19
- 239000005761 Dimethomorph Substances 0.000 abstract description 19
- 239000005807 Metalaxyl Substances 0.000 abstract description 18
- ZQEIXNIJLIKNTD-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate Chemical compound COCC(=O)N(C(C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-UHFFFAOYSA-N 0.000 abstract description 18
- 150000001875 compounds Chemical class 0.000 abstract description 16
- 230000000855 fungicidal effect Effects 0.000 abstract description 9
- 238000001228 spectrum Methods 0.000 abstract description 2
- 238000005406 washing Methods 0.000 abstract 1
- 238000013329 compounding Methods 0.000 description 38
- 238000012360 testing method Methods 0.000 description 37
- 239000003814 drug Substances 0.000 description 36
- 230000003449 preventive effect Effects 0.000 description 27
- 230000002265 prevention Effects 0.000 description 26
- 239000000575 pesticide Substances 0.000 description 22
- 238000002474 experimental method Methods 0.000 description 21
- 239000012071 phase Substances 0.000 description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 240000008067 Cucumis sativus Species 0.000 description 14
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 14
- 239000002518 antifoaming agent Substances 0.000 description 12
- 239000002270 dispersing agent Substances 0.000 description 12
- 231100000820 toxicity test Toxicity 0.000 description 12
- 239000000126 substance Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 10
- 206010067482 No adverse event Diseases 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 8
- 239000008367 deionised water Substances 0.000 description 8
- 229910021641 deionized water Inorganic materials 0.000 description 8
- 239000003995 emulsifying agent Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 239000002904 solvent Substances 0.000 description 8
- 239000002562 thickening agent Substances 0.000 description 8
- 239000000080 wetting agent Substances 0.000 description 8
- 241000208293 Capsicum Species 0.000 description 7
- 235000002566 Capsicum Nutrition 0.000 description 7
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 7
- 240000003768 Solanum lycopersicum Species 0.000 description 7
- WHDHEVMINMZADQ-UHFFFAOYSA-N [F].N1C=CC=C1 Chemical class [F].N1C=CC=C1 WHDHEVMINMZADQ-UHFFFAOYSA-N 0.000 description 7
- 150000001408 amides Chemical class 0.000 description 7
- 239000001390 capsicum minimum Substances 0.000 description 7
- 239000000417 fungicide Substances 0.000 description 7
- 230000005764 inhibitory process Effects 0.000 description 7
- 241000233614 Phytophthora Species 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 6
- 235000013399 edible fruits Nutrition 0.000 description 6
- -1 pyrazole amide Chemical class 0.000 description 6
- 239000000243 solution Substances 0.000 description 5
- 241000219109 Citrullus Species 0.000 description 4
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 4
- 244000183278 Nephelium litchi Species 0.000 description 4
- 241000209140 Triticum Species 0.000 description 4
- 235000021307 Triticum Nutrition 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 230000002045 lasting effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 241000233654 Oomycetes Species 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 230000010165 autogamy Effects 0.000 description 3
- 238000000498 ball milling Methods 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 230000010534 mechanism of action Effects 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- 206010011732 Cyst Diseases 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000005808 Metalaxyl-M Substances 0.000 description 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 125000002252 acyl group Chemical group 0.000 description 2
- 150000001412 amines Chemical group 0.000 description 2
- 150000003851 azoles Chemical class 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 208000031513 cyst Diseases 0.000 description 2
- 238000002242 deionisation method Methods 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- ZQEIXNIJLIKNTD-GFCCVEGCSA-N metalaxyl-M Chemical compound COCC(=O)N([C@H](C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-GFCCVEGCSA-N 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- 239000003002 pH adjusting agent Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- CTMPZHHYIJWHHL-UHFFFAOYSA-N 1,2,3-trifluoro-5-phenylbenzene Chemical compound FC1=C(F)C(F)=CC(C=2C=CC=CC=2)=C1 CTMPZHHYIJWHHL-UHFFFAOYSA-N 0.000 description 1
- RHLCLUWWRHEMDQ-UHFFFAOYSA-N 3-(dimethylamino)propylcarbamic acid Chemical compound CN(C)CCCNC(O)=O RHLCLUWWRHEMDQ-UHFFFAOYSA-N 0.000 description 1
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 description 1
- WVSBBCCXKUUWGB-ZETCQYMHSA-N COC([C@@H](NCCC)CCO)=O Chemical class COC([C@@H](NCCC)CCO)=O WVSBBCCXKUUWGB-ZETCQYMHSA-N 0.000 description 1
- 102100025287 Cytochrome b Human genes 0.000 description 1
- 108010075028 Cytochromes b Proteins 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000192128 Gammaproteobacteria Species 0.000 description 1
- 241000545744 Hirudinea Species 0.000 description 1
- MKIMSXGUTQTKJU-UHFFFAOYSA-N Propamocarb hydrochloride Chemical compound [Cl-].CCCOC(=O)NCCC[NH+](C)C MKIMSXGUTQTKJU-UHFFFAOYSA-N 0.000 description 1
- 241000233639 Pythium Species 0.000 description 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 239000010242 baoji Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000003592 biomimetic effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000002508 compound effect Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- PQIOSYKVBBWRRI-UHFFFAOYSA-N methylphosphonyl difluoride Chemical group CP(F)(F)=O PQIOSYKVBBWRRI-UHFFFAOYSA-N 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 231100000194 ovacidal Toxicity 0.000 description 1
- 230000003151 ovacidal effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 229960004257 sulfaguanidine Drugs 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- ABDKAPXRBAPSQN-UHFFFAOYSA-N veratrole Chemical class COC1=CC=CC=C1OC ABDKAPXRBAPSQN-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of bactericidal composition of Fluxapyroxad-containsterilization, the bactericidal composition containing active components A Yu active constituent B, active components A is selected from fluxapyroxad, and active constituent B is selected from any one following compound:Cyazofamid, dimethomorph, Propamocarb or its salt, cymoxanil, metalaxyl or its salt, iprovalicarb, and active components A and the weight ratio of active constituent B are 1 ︰, 80~60 ︰ 1.The present composition has the multiple diseases in various crop greater activity, and with apparent synergistic effect, expands fungicidal spectrum.And with the characteristics of dosage is small, resistance of rainwater washing against, and synergy is apparent.
Description
The application is divisional application, and for the patent application of Shaanxi Welch Crop Protection Co., Ltd., " one kind contains for original application
The bactericidal composition of fluxapyroxad ", the application Wei ︰ 2012101663991 of original application, original application day 2012.05.25.
Technical field
The invention belongs to technical field of pesticide, are related to a kind of bactericidal composition of Fluxapyroxad-containsterilization in crop disease
Using.
Technical background
Fluxapyroxad (Fluxapyroxad) chemical name:3- (difluoro) -1- methyl-N- (3', 4', 5'- trifluoro [1,
1'- biphenyl] -2- bases) -1-H- pyrazoles -4- amides, fluxapyroxad category pyrazole amide series bactericidal agent, succinate dehydrogenase inhibition
Agent.Superior lasting effect and lasting transmission characteristic are integrated in one.
Cyazofamid (Cyazofamid) chemical name:The chloro- 2- cyano -5- p-methylphenyls of 4--imidazoles -1-N, N- dimethyl
Leech amide, molecular formula:C13H13ClN4O2S.It is sulphaguanidine azoles fungicide, super protective fungicide.Mechanism of action is resistance
The electron transmission of mitochondrial cytochrome b c1 complexs comes the supply of interfering energy, binding site in disconnected Oomycete germ body
For the Q1 centers of enzyme, with other fungicide without cross tolerance.Its high selection activity to pathogen may be due to target enzymes pair
Caused by the sensitivity difference of medicament.
Dimethomorph (Dimethomorph) chemical name:(E, Z) -4- [3- (4- chlorphenyls) 3- (3,4- dimethoxy benzenes
Base) acryloyl] morpholine, molecular formula:C21H22ClNO4.Dimethomorph is single-minded ovicidal Gammaproteobacteria fungal fungicide, and action character is
The formation of cell envelope is destroyed, has effect to each stage of oomycetes history of life, in the formation rank of sporangiophore and egg spore
Section is particularly sensitive, at much lower concentrations (<0.25 μ g/ml) it is suppressed.With phenylamide medicament no interactions resistance.
Propamocarb (Propamocarb) chemical name:3- (dimethylamino) propyl carbamic acid propyl ester, molecular formula:
C9H21N2O2Cl.The salt of Propamocarb can be propamocarb (Propamocarb hydrochloride), chemical name:Third
Base -3- (dimethylamino) propyl carbamic acid hydrochloride.Propamocarb or its salt are respectively provided with local systemic action, also can be used as soaking
Stain processing and seed protectant.
Cymoxanil (Cymoxanil) chemical name:2- cyano-N- [(ethylamino-) carbonyl] -2- (methoxyl group imido grpup) second
Amide, molecular formula:C7H10N4O3, there is contact and local systemic action, spore germination is can inhibit, to downy mildew of garpe, epidemic disease etc.
Effectively, it is mixed with protective fungicide to extend the lasting period.
Metalaxyl (Metalaxyl) chemical name:D, L-N- (2,6- 3,5-dimethylphenyls)-N- (2'- methoxyl groups acetyl) third
Propylhomoserin methyl esters, molecular formula:C15H21NO4.The salt of metalaxyl can be Metalaxyl-M (Metalaxyl-M), chemical name:N-(2,
6- xylyls)-N- (Methoxyacetyl)-D- alanine methyl esters.Metalaxyl or its salt be with protection and therapeutic effect, it is simultaneous
Have systemic action, can be absorbed by the root, stem, leaf of plant, and operate and be transferred to each organ of plant with plant moisture in vivo, it can
It is effective to the disease caused by downy mildew, phytophthora, pythium spp to make cauline leaf process, seed treatment and soil treatment.
Iprovalicarb (Iprovalicarb) chemical name:[2- methyl-1s-[1- (4- aminomethyl phenyls)-ethylcarbamoyl
Base]-propyl]-carbamyl isopropyl ester, molecular formula:C18H28N2O3.Iprovalicarb is amino-acid ester analog derivative, is had unique
Completely new biomimetic features make its mechanism of action be different from other fungicide for preventing Oomycetes.Its mechanism of action is thin to act on fungi
The synthesis of cell wall and protein can inhibit infecting and sprouting for spore, while can inhibit mycelial growth, it is caused to deform,
It is dead.There is treatment and eradicant action well for Peronosporaceae and the fungus-caused disease of Phytophthora.
In the real process of agricultural production, controlling disease is easiest to generate the problem that the generation of disease drug resistance.No
It is compounded with kind ingredient, is to prevent the very common method of resistance disease.Heterogeneity is compounded, and is imitated according to practical application
Fruit, to judge that certain compounding is synergy, adduction or antagonism.In most cases, the compounding effect of pesticide is all to add
And effect, the compounding for really having synergistic effect is seldom, especially synergistic effect clearly, the very high compounding of synergy ratio just more
It is few.It studies, is found fluxapyroxad and cyazofamid, dimethomorph, Propamocarb or its salt, cymoxanil, first by inventor
White spirit or its salt, iprovalicarb mutually compound, and have good synergistic effect in a certain range, and in relation to fluxapyroxad and cyanogen frost
The related compounding of azoles, dimethomorph, Propamocarb or its salt, cymoxanil, metalaxyl or its salt, iprovalicarb, at present at home and abroad still
Have no relevant report.
Invention content
There is synergistic function, the fluorine-containing azoles bacterium acyl that use cost is low, preventive effect is good the purpose of the present invention is to propose to a kind of
The bactericidal composition of amine.
The present invention is to be achieved through the following technical solutions:
A kind of bactericidal composition of Fluxapyroxad-containsterilization, it is characterised in that contain active components A and active constituent B, activity
Ingredient A is 1 ︰, 80~60 ︰ 1 with active constituent B weight ratios, and the active components A is selected from fluxapyroxad, active constituent B choosings
From one of cyazofamid, dimethomorph, Propamocarb or its salt, cymoxanil, metalaxyl or its salt, iprovalicarb kind.Active components A with
The preferred weight ratio of active constituent B is 1 ︰, 50~40 ︰ 1;More preferably the weight ratio of fluxapyroxad and cyazofamid for 1 ︰ 20~
20 ︰ 1;Fluxapyroxad and the weight ratio of dimethomorph are 1 ︰, 25~10 ︰ 1;Fluxapyroxad and the weight of Propamocarb or its salt
Than for 1 ︰, 40~5 ︰ 1;The weight ratio of fluxapyroxad and cymoxanil is 1 ︰, 30~15 ︰ 1;Fluxapyroxad and metalaxyl or its salt
Weight ratio be 1 ︰, 30~5 ︰ 1;Fluxapyroxad and the weight ratio of iprovalicarb are 1 ︰, 30~20 ︰ 1.
The bactericidal composition of the Fluxapyroxad-containsterilization is used to preventing the disease of crop, the crop include fruit tree,
Vegetables, cereal crops, ornamental plant.
The disease include moire disease, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease,
Balck shank, samping off, white rot, anthracnose, white blister, foot rot.
The amount of application when content of active constituent depends on being used alone in the present composition, also depends on a kind of chemical combination
Object and another mixed ratio of compound and synergistic effect degree, at the same it is also related with target disease.In usual composition
The weight percentage of active constituent be total weight 1%~90%, preferably 5%~80%.According to different preparation classes
Type, active component content range are different.In general, liquid preparation contains by weight 1%~60% active material, preferably
Ground is 5%~50%;Solid pharmaceutical preparation contains by weight 5%~80% active material, preferably 10%~80%.
At least containing a kind of surfactant in the bactericidal composition of the present invention, so that active constituent is in water during application
Dispersion.Surface-active contents are the 2%~30% of total formulation weight, and surplus is solid or liquid diluent.
Surfactant selected by the bactericidal composition of the present invention is known in those skilled in the art:It can be selected from
One or more of dispersant, wetting agent, thickener or antifoaming agent.According to different dosage forms, this field can also be contained in preparation
Stabilizer, antifreeze well known to technical staff etc..
The bactericidal composition of the present invention can be used through dilution or directly before use by user.Its preparation can be by ability
Prepared by the processing method well known to field technique personnel, i.e., after active constituent is mixed with liquid flux or solid carrier, add
Surfactant such as one or more of dispersant, stabilizer, wetting agent, binding agent, antifoaming agent etc..
The bactericidal composition of the present invention, can be processed into acceptable dosage form on any pesticide on demand.Wherein preferred agent
Type is wettable powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-outstanding
Floating agent, may be made as aqua, soluble liquid, soluble powder.
Comprising following component and content when wettable powder is made in composition:Active components A 1%~60%, active constituent
B 1%~80%, dispersant 1%~12%, wetting agent 1%~8%, filler surplus.
Composition includes following component and content when water dispersible granules are made:Active components A 1%~60%, active constituent
B 1%~80%, dispersant 1%~12%, wetting agent 1%~8%, disintegrant 1%~10%, binding agent 0~8%, filler
Surplus.
Composition includes following component and content when suspending agent is made:Active components A 1%~50%, active constituent B
1%~50%, dispersant 1%~10%, wetting agent 1%~10%, antifoaming agent 0.01%~2%, thickener 0~2%, freeze proof
Agent 0~8%, deionized water add to 100%.
Composition includes following component and content when suspension emulsion is made:Active components A 1%~50%, active constituent B
1%~50%, emulsifier 1%~10%, dispersant 1%~10%, solvent 0~20%, antifoaming agent 0.01%~2%, thickening
Agent 0~2%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when microemulsion is made:Active components A 1%~50%, active constituent B
1%~50%, emulsifier 3%~25%, solvent 1%~10%, antifreeze 0~8%, antifoaming agent 0.01%~2%, deionization
Water adds to 100%.
Composition includes following component and content when aqueous emulsion is made:Active components A 1%~50%, active constituent B
1%~50%, solvent 1%~20%, emulsifier 1%~12%, antifreeze 0~8%, antifoaming agent 0.01%~2%, thickener
0~2%, deionized water adds to 100%.
The wettable powder the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The advantage of the invention is that:
(1) present composition has good synergy and lasting effect in a certain range, and preventive effect is higher than single dose;(2) agriculture
Medicinal dose is reduced, and is reduced residual quantity of the pesticide on crop, is mitigated environmental pollution;(3) fungicidal spectrum is expanded, to multiple diseases
As moire disease, leaf spot, net blotch, rust, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, samping off, white rot,
Anthracnose, white blister, foot rot have greater activity.
Specific embodiment
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The present invention is not limited thereto.
Application Example one
1~20 wettable powder of example
Fluxapyroxad, active constituent B, dispersant, wetting agent, filler are mixed, are uniformly mixed in mixed cylinder, through gas
Stream pulverizer remixes uniformly after crushing, you can wettable powder product of the present invention is made.Specifically it is shown in Table 1,2.
1 example of table, 1~10 each component and content
2 example of table, 11~20 each component and content
21~40 water dispersible granules of example
By fluxapyroxad, active constituent B, dispersant, wetting agent, disintegrant, binding agent (can add can be not added with), filler one
The grain size needed through air-flow crushing is played, obtains granulation materials.Item is quantified to be sent into fluidized bed granulating dryer and is passed through
After granulation and drying, water dispersible granules product of the present invention is made.Specifically it is shown in Table 3,4.
3 example of table, 21~30 each component and content
4 example of table, 31~40 each component and content
41~58 suspending agent of example
By dispersant, wetting agent, thickener (can add can be not added with), antifoaming agent, antifreeze (can add can be not added with) by a high speed
Shear-mixed is uniform, adds in fluxapyroxad, active constituent B, supplies surplus with deionized water, ball milling 2~3 is small in the ball mill
When, make diameter of particle all at 5 μm hereinafter, suspending agent product of the present invention is made.Specifically it is shown in Table 5,6.
5 example of table, 41~50 each component and content
6 example of table, 51~58 each component and content
Cyazofamid, dimethomorph, Propamocarb or its salt, cymoxanil, metalaxyl, iprovalicarb in table 1 to table 6 are exchanged, it can
Novel formulation is made.
59~71 suspension emulsion of example
By dispersant, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with), deionized water through excessively high
Fast shear-mixed is uniform, adds in fluxapyroxad, ball milling 2~3 hours in the ball mill, make diameter of particle all at 5 μm hereinafter,
Fluxapyroxad suspending agent is made, then by active constituent B, solvent (can add can be not added with), emulsifier and various auxiliary agents at a high speed
Blender is directly emulsified into suspending agent, and suspension emulsion product of the present invention is made.Specifically it is shown in Table 7,8.
7 example of table, 59~67 each component and content
8 example of table, 65~71 each component and content
72~81 aqueous emulsion of example
Fluxapyroxad, active constituent B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase;By deionization
Water, antifreeze (can add can be not added with), thickener (can add can be not added with), antifoaming agent mix, into uniform water phase.In high-speed stirring
It mixes down, water phase is added in into oil phase, aqueous emulsion product of the present invention is made.Specifically it is shown in Table 9.
9 example of table, 72~81 each component and content
Cyazofamid, dimethomorph, Propamocarb or its salt, cymoxanil, metalaxyl or its salt, iprovalicarb in table 7 to table 9 is mutual
It changes, novel formulation can be made.
82~84 microemulsion of example
Fluxapyroxad, active constituent B are dissolved in the homogenizer equipped with solvent, by emulsifier, antifreeze, (can add can
Be not added with), antifoaming agent be added in the homogenizer equipped with above-mentioned solution, give after supplying surplus with deionized water strongly mixing and it is even
Change, finally obtain the transparent microemulsion product of the present invention of clear appearance.Specifically it is shown in Table 10.
10 example of table, 82~84 each component and content
Example 85,86 microcapsule suspending agents
Fluxapyroxad, active constituent B, macromolecule cyst material, solvent are mixed, makes to be dissolved into homogeneous oil phase, cut
Under tangent condition, by oil phase be added to containing emulsifier, pH adjusting agent, dispersant, antifoaming agent aqueous phase solution in, use deionized water
Surplus is supplied, two kinds of materials react in oil-water interfaces, form high score ascus wall, it is well dispersed that the present composition is made
Microcapsule suspending agent product.Specifically it is shown in Table 11.
11 example 85 of table, 86 each components and content
Example 87,88 microcapsule suspension-suspendinagent agents
Active constituent B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, by oil phase in shearing condition
Under be added to containing emulsifier, pH adjusting agent aqueous phase solution in, well dispersed microcapsule suspending agent is made.By dispersant, wet
Profit agent, antifoaming agent, thickener (can add can be not added with) are uniformly mixed by high speed shear, add in fluxapyroxad, in the ball mill
Ball milling 2~3 hours, makes diameter of particle all at 5 μm hereinafter, suspending agent is made, and suspending agent then is added to microcapsules suspends
In the aqueous phase solution of agent, deionized water supplies surplus, and the well dispersed microcapsule suspension-suspendinagent agent production of the present composition is made
Product.Specifically it is shown in Table 12.
12 example 87 of table, 88 each components and content
The embodiment of the present invention is the method being combined using Toxicity Determination and field trial.First pass through indoor virulence survey
It is fixed, clear and definite two kinds of medicaments compound by a certain percentage after synergy ratio (SR), SR < 0.5 are antagonism, 0.5≤SR≤1.5
For summation action, SR > 1.5 are synergistic effect, on this basis, then carry out field trial.
Test method:After prerun determines the effective inhibition concentration range of each medicament, medicament sets 5 respectively by active constituent content
A dosage processing, if clear water compares.Reference《Farm-chemical indoor determination test rule fungicide》It carries out, speed is grown using mycelia
Rate method measures virulence of the medicament to crop germ.Colony diameter is measured with crossing method after 72h, calculates the net growth of each processing
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter -5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) is converted into logarithm (x), with minimum
Square law acquires virulence regression equation (y=a+bx), and thus calculates the EC of each medicament50Value.Simultaneously according to Wadley methods
Two medicament different ratio synergy ratios (SR) are calculated, SR < 0.5 are antagonism, and 0.5≤SR≤1.5 are summation action,
SR > 1.5 are synergistic effect.Calculation formula is as follows:
Wherein:A, b is respectively active components A and active constituent B ratio shared in combination;A is fluxapyroxad;B
Choosing is to one of cyazofamid, dimethomorph, Propamocarb or its salt, cymoxanil, metalaxyl or its salt, iprovalicarb kind.
Application Example two:
For trying disease:Tomato late blight;Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd.;Experiment is set
Meter:Fluxapyroxad and cyazofamid active compound and effective inhibition concentration model of the two different ratio mixture are determined by pilot study
It encloses.
Toxicity test result
13 fluxapyroxad of table compounds the toxicity test analysis of results table to tomato late blight with cyazofamid
As shown in Table 13, fluxapyroxad compounds the proportioning for preventing tomato late blight in 1 80~60 ︰ 1 of ︰ with cyazofamid,
Synergy ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, when fluorine azoles bacterium acyl
For the proportioning of amine and cyazofamid in 1 20~20 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is all higher than 2.20.It is found through experiment that
The optimum ratio of fluxapyroxad and cyazofamid is 20:1、15:1、10:1、9:1、8:1、7:1、6:1、5:1、4:1、3:1、2:1、
1:1、1:2、1:3、1:4、1:5、1:6、1:7、1:8、1:9、1:10、1:15、1:20, especially when fluxapyroxad and cyazofamid
Weight ratio is 1:Synergy ratio is maximum when 1, and synergistic effect is the most apparent.
Application Example three:
For trying disease:Cucumber downy mildew;Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd.;Experiment is set
Meter:Fluxapyroxad and dimethomorph active compound and effective inhibition concentration model of the two different ratio mixture are determined by pilot study
It encloses.
Toxicity test result
14 fluxapyroxad of table compounds the toxicity test analysis of results table to cucumber downy mildew with dimethomorph
As shown in Table 14, fluxapyroxad prevents the proportioning of cucumber downy mildew in 1 ︰, 80~60 ︰ 1 with dimethomorph compounding
When, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, when fluorine azoles
For the proportioning of bacterium amide and dimethomorph in 1 25~10 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is all higher than 2.30.Through examination
The optimum ratio for issuing after examination and approval existing fluxapyroxad and dimethomorph is 10:1、9:1、8:1、7:1、6:1、5:1、4:1、3:1、2:1、1:
1、1:2、2:5、1:3、1:4、1:5、1:6、1:7、1:8、1:9、1:10、1:15、1:20、1:25, especially work as fluxapyroxad
It is 2 with dimethomorph weight ratio:Synergy ratio is maximum when 5, and synergistic effect is the most apparent.
Application Example four:
For trying disease:Cucumber Blight;Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd.;Experiment is set
Meter:Determine that fluxapyroxad and the effectively inhibition of Propamocarb or its salt active compound and the two different ratio mixture are dense by pilot study
Spend range.
Toxicity test result
15 fluxapyroxad of table compounds the toxicity test analysis of results table to Cucumber Blight with Propamocarb or its salt
As shown in Table 15, fluxapyroxad compounds the proportioning of cucumber blight disease in 1 ︰, 80~60 ︰ 1 with Propamocarb or its salt
When, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, when fluorine azoles
Bacterium amide is with the proportioning of Propamocarb or its salt in 1 40~5 ︰ 1 of ︰, and synergistic effect is more prominent, and synergy ratio is all higher than 2.30.
It is found through experiment that fluxapyroxad is 5 with the optimum ratio of Propamocarb or its salt:1、1:1、1:2、1:3、1:4、1:5、1:6、1:
7、1:8、1:9、1:10、1:11、1:12、1:13、1:14、1:15、1:20、1:25、1:30、1:35、1:40, especially when fluorine azoles
Bacterium amide is 1 with Propamocarb or its salt weight ratio:Synergy ratio is maximum when 8, and synergistic effect is the most apparent.
Application Example five:
For trying disease:Downy mildew of crucifers;Test medicine is carried by Shaanxi Welch Crop Protection Co., Ltd.
For;Experimental design:Fluxapyroxad and effective suppression of cymoxanil active compound and the two different ratio mixture are determined by pilot study
Concentration range processed.
Toxicity test result
16 fluxapyroxad of table compounds the toxicity test analysis of results table to downy mildew of crucifers with cymoxanil
As shown in Table 16, the proportioning of fluxapyroxad and cymoxanil compounding prevention downy mildew of crucifers 1 ︰ 80~
During 60 ︰ 1, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, when
For the proportioning of fluxapyroxad and cymoxanil in 1 30~15 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is all higher than 2.30.Through
Experiment finds that the optimum ratio of fluxapyroxad and cymoxanil is 15:1、10:1、9:1、8:1、7:1、6:1、5:1、4:1、3:1、
2:1、1:1、1:2、1:3、1:4、1:5、1:6、1:7、1:8、1:9、1:10、1:15、1:20、1:25、1:30, especially when fluorine azoles
Bacterium amide is 1 with cymoxanil weight ratio:Synergy ratio is maximum when 2, and synergistic effect is the most apparent.
Application Example six:
For trying disease:Downy mildew of garpe;Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd.;Experiment is set
Meter:Determine that fluxapyroxad and the effectively inhibition of metalaxyl or its salt active compound and the two different ratio mixture are dense by pilot study
Spend range.
Toxicity test result
17 fluxapyroxad of table compounds the toxicity test analysis of results table to downy mildew of garpe with metalaxyl or its salt
As shown in Table 17, the proportioning of fluxapyroxad and metalaxyl or its salt compounding prevention downy mildew of garpe 1 ︰ 80~
During 60 ︰ 1, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, when
Fluxapyroxad is with the proportioning of metalaxyl or its salt in 1 30~5 ︰ 1 of ︰, and synergistic effect is more prominent, and synergy ratio is all higher than
2.20.Especially when fluxapyroxad and metalaxyl or its salt weight ratio are 1:Synergy ratio is maximum when 6, and synergistic effect is the brightest
It is aobvious.
Application Example seven:
For trying disease:Capsicum epidemic disease;Test medicine is provided by Shaanxi Welch Crop Protection Co., Ltd.;Experiment is set
Meter:Fluxapyroxad and iprovalicarb active compound and effective inhibition concentration model of the two different ratio mixture are determined by pilot study
It encloses.
Toxicity test result
18 fluxapyroxad of table compounds the toxicity test analysis of results table to capsicum epidemic disease with iprovalicarb
As shown in Table 18, fluxapyroxad increases with the proportioning of iprovalicarb compounding prevention capsicum epidemic disease in 1 80~60 ︰ 1 of ︰
Effect ratio SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~60 ︰ 1 shows synergistic effect, works as fluxapyroxad
For proportioning with iprovalicarb in 1 30~20 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is all higher than 2.20.Especially when fluorine azoles
Bacterium amide is 2 with iprovalicarb weight ratio:Synergy ratio is maximum when 3, and synergistic effect is the most apparent.
It is found through experiment that:To moire disease, leaf spot, net blotch, rust, evening after fluxapyroxad and active constituent B compoundings
The prevention of epidemic disease, downy mildew, peronospora tabacina, epidemic disease, balck shank, samping off, white rot, anthracnose, white blister, foot rot has
Apparent synergistic effect, synergy ratio is more than 1.50.
Test of pesticide effectiveness part
Test medicine is researched and developed by Shaanxi Welch Crop Protection Co., Ltd., provided.Comparison medicament:10% fluorine azoles bacterium acyl
Amine suspending agent (autogamy), 100g/L cyazofamids suspending agent (purchased in market), 50% dimethomorph wettable powder (purchased in market), 35% downy mildew
Prestige aqua (purchased in market), 25% cymoxanil wettable powder (autogamy), 25% metalaxyl wettable powder (purchased in market), 20% iprovalicarb
Wettable powder (autogamy).
Eight fluxapyroxad of Application Example and active constituent B and its compounding prevention tomato late blight test of pesticide effectiveness
This test arrangement investigates the tomato late blight state of an illness before Xian District, Shanxi Province suburban area, medicine, in first time at state of an illness initial stage
Dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and is calculated anti-within 14 days, 30 days
Effect.Experimental result is as follows:
19 fluxapyroxad of table and active constituent B and its compounding prevention tomato late blight test of pesticide effectiveness
As can be seen from Table 19, tomato late blight, prevention effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
Nine fluxapyroxad of Application Example and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
This test arrangement investigates the cucumber downy mildew state of an illness before Shaanxi Province Jingyang County, medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.It is real
It is as follows to test result:
20 fluxapyroxad of table and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
As can be seen from Table 20, cucumber downy mildew, prevention effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
Ten fluxapyroxad of Application Example and active constituent B and its compounding prevention downy mildew of garpe test of pesticide effectiveness
This test arrangement investigates the downy mildew of garpe state of an illness before Shaanxi Province Weinan suburban area, medicine, in first time at state of an illness initial stage
Dispenser, every dispenser in 7 days is primary, altogether dispenser 3 times.7 days after last dispenser, disease index is investigated respectively and is calculated anti-within 14 days, 30 days
Effect.Experimental result is as follows:
21 fluxapyroxad of table and active constituent B and its compounding prevention downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 21, downy mildew of garpe, prevention effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
11 fluxapyroxad of Application Example and active constituent B and its compounding prevention watermelon epidemic disease test of pesticide effectiveness
This test arrangement investigates the watermelon epidemic disease state of an illness before Shaanxi Province Weinan City Dali County, medicine, in first time at state of an illness initial stage
Dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and is calculated anti-within 14 days, 30 days
Effect.Experimental result is as follows:
22 fluxapyroxad of table and active constituent B and its compounding prevention watermelon epidemic disease test of pesticide effectiveness
As can be seen from Table 22, watermelon epidemic disease, control effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
The preventive effect of single dose is superior to, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
12 fluxapyroxad of Application Example and active constituent B and its compounding prevention wheat rust test of pesticide effectiveness
This test arrangement investigates the wheat rust state of an illness before Shaanxi Province's Weinan City, medicine, in state of an illness first time at initial stage dispenser, often
Dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.Experiment
As a result it is as follows:
23 fluxapyroxad of table and active constituent B and its compounding prevention wheat rust test of pesticide effectiveness
As can be seen from Table 23, wheat rust, control effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
The preventive effect of single dose is superior to, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
13 fluxapyroxad of Application Example and active constituent B and its compounding prevention downy mildew of crucifers medicine
Effect experiment
This test arrangement investigates the downy mildew of crucifers state of an illness before Xian District, Shanxi Province suburban area, medicine, at the beginning of the state of an illness
The dispenser of first time phase, every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively within 14 days, 30 days
And calculate preventive effect.Experimental result is as follows:
24 fluxapyroxad of table and active constituent B and its compounding prevention downy mildew of crucifers test of pesticide effectiveness
As can be seen from Table 24, brassicaceous vegetable downy mildew can effectively be prevented after fluxapyroxad and active constituent B compoundings
Disease, control effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
14 fluxapyroxad of Application Example and active constituent B and its compounding prevention peronophythora litchi test of pesticide effectiveness
This test arrangement investigates the peronophythora litchi state of an illness before Guangdong Province Huilai county, medicine, is applied for the first time in state of an illness initial stage
Medicine, every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows:
25 fluxapyroxad of table and active constituent B and its compounding prevention peronophythora litchi test of pesticide effectiveness
As can be seen from Table 25, peronophythora litchi can be effectively prevented after fluxapyroxad and active constituent B compoundings, prevented
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
15 fluxapyroxad of Application Example and active constituent B and its compounding prevention cucumber samping off test of pesticide effectiveness
This test arrangement investigates the cucumber samping off state of an illness before Shaanxi Province Jingyang County, medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.It is real
It is as follows to test result:
26 fluxapyroxad of table and active constituent B and its compounding prevention cucumber samping off test of pesticide effectiveness
As can be seen from Table 26, cucumber samping off, prevention effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
16 fluxapyroxad of Application Example and active constituent B and its compounding prevention capsicum epidemic disease test of pesticide effectiveness
This test arrangement investigates the capsicum epidemic disease state of an illness before Qishan County of Baoji, Shaanxi province city, medicine, in first time at state of an illness initial stage
Dispenser, every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after last dispenser, disease index is investigated respectively and is calculated anti-within 14 days, 30 days
Effect.Experimental result is as follows:
27 fluxapyroxad of table and active constituent B and its compounding prevention capsicum epidemic disease test of pesticide effectiveness
As can be seen from Table 27, capsicum epidemic disease, control effect can effectively be prevented after fluxapyroxad and active constituent B compoundings
The preventive effect of single dose is superior to, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
The experiment by different places throughout the country obtains afterwards, fluxapyroxad and cyazofamid, dimethomorph, Propamocarb
Or to moire disease, leaf spot, net blotch, the rust in various crop after its salt, cymoxanil, metalaxyl or its salt, iprovalicarb compounding
Disease, late blight, downy mildew, peronospora tabacina, epidemic disease, balck shank, samping off, white rot, anthracnose, white blister, foot rot etc. are normal
The preventive effect of disease is seen more than 95%, and better than single dose preventive effect, synergistic effect is apparent.
Claims (6)
1. a kind of bactericidal composition of Fluxapyroxad-containsterilization, it is characterised in that:Effective active composition for active components A with activity into
Point B, active components A and active constituent B weight ratios are 1 ︰, 80~60 ︰ 1, and the active components A is fluxapyroxad, activity into
Point B is selected from one of cyazofamid, Propamocarb or its salt, cymoxanil, iprovalicarb kind.
2. the bactericidal composition of Fluxapyroxad-containsterilization according to claim 1, it is characterised in that:Active components A and activity
The weight ratio of ingredient B is 1 ︰, 50~40 ︰ 1.
3. the bactericidal composition of Fluxapyroxad-containsterilization according to claim 2, it is characterised in that:
Fluxapyroxad and the weight ratio of cyazofamid are 1 ︰, 20~20 ︰ 1;
Fluxapyroxad is 1 ︰, 40~5 ︰ 1 with the weight ratio of Propamocarb or its salt;
The weight ratio of fluxapyroxad and cymoxanil is 1 ︰, 30~15 ︰ 1;
Fluxapyroxad and the weight ratio of iprovalicarb are 1 ︰, 30~20 ︰ 1.
4. the bactericidal composition of the Fluxapyroxad-containsterilization according to any one in claim 1-3, it is characterised in that:Combination
Object be made wettable powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-
Suspending agent.
5. the bactericidal composition of Fluxapyroxad-containsterilization according to claim 4 is used to prevent the application of crop disease.
6. application according to claim 5, it is characterised in that:The disease include moire disease, leaf spot, net blotch,
Rust, downy mildew, peronospora tabacina, epidemic disease, balck shank, samping off, white rot, anthracnose, foot rot.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610117912.6A CN105724386B (en) | 2012-05-25 | 2012-05-25 | A kind of bactericidal composition of Fluxapyroxad-containsterilization |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610117912.6A CN105724386B (en) | 2012-05-25 | 2012-05-25 | A kind of bactericidal composition of Fluxapyroxad-containsterilization |
CN201210166399.1A CN103416417B (en) | 2012-05-25 | 2012-05-25 | The fungicidal composition of a kind of fluorine-containing azoles bacterium acid amides |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210166399.1A Division CN103416417B (en) | 2012-05-25 | 2012-05-25 | The fungicidal composition of a kind of fluorine-containing azoles bacterium acid amides |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105724386A CN105724386A (en) | 2016-07-06 |
CN105724386B true CN105724386B (en) | 2018-06-26 |
Family
ID=56248975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610117912.6A Expired - Fee Related CN105724386B (en) | 2012-05-25 | 2012-05-25 | A kind of bactericidal composition of Fluxapyroxad-containsterilization |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105724386B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113317319B (en) * | 2021-06-21 | 2022-10-21 | 青岛瀚生生物科技股份有限公司 | Composite bactericide and application thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101257798A (en) * | 2005-08-05 | 2008-09-03 | 巴斯福股份公司 | Fungicidal mixtures containing substituted 1-methyl pyrazol-4-yl carboxylic acid anilides |
CN101658177A (en) * | 2009-07-22 | 2010-03-03 | 深圳诺普信农化股份有限公司 | Complex bactericidal composition containing cyazofamid |
DE102011017670A1 (en) * | 2010-04-29 | 2011-11-03 | Basf Se | Composition, useful e.g. for combating phytopathogenic harmful fungi, e.g. soil-borne pathogens, from classes of Plasmodiophoromycetes, comprises 2',4'-dimethoxy-4-cyclopropyl-1,2,3-thiadiazol-5-carboxanilide and fluxapyroxad |
CN102415392A (en) * | 2011-12-23 | 2012-04-18 | 江阴苏利化学有限公司 | Germicide composition containing boscalid and cymoxanil |
-
2012
- 2012-05-25 CN CN201610117912.6A patent/CN105724386B/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101257798A (en) * | 2005-08-05 | 2008-09-03 | 巴斯福股份公司 | Fungicidal mixtures containing substituted 1-methyl pyrazol-4-yl carboxylic acid anilides |
CN101658177A (en) * | 2009-07-22 | 2010-03-03 | 深圳诺普信农化股份有限公司 | Complex bactericidal composition containing cyazofamid |
DE102011017670A1 (en) * | 2010-04-29 | 2011-11-03 | Basf Se | Composition, useful e.g. for combating phytopathogenic harmful fungi, e.g. soil-borne pathogens, from classes of Plasmodiophoromycetes, comprises 2',4'-dimethoxy-4-cyclopropyl-1,2,3-thiadiazol-5-carboxanilide and fluxapyroxad |
CN102415392A (en) * | 2011-12-23 | 2012-04-18 | 江阴苏利化学有限公司 | Germicide composition containing boscalid and cymoxanil |
Also Published As
Publication number | Publication date |
---|---|
CN105724386A (en) | 2016-07-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103858882B (en) | A kind of composition pesticide containing ZEN 90160 and amide-type | |
CN103416428A (en) | Fluxapyroxad-containing sterilization composition | |
CN104412982B (en) | A kind of compound highly effective bactericidal composition of fluorine-containing ether bacterium amide | |
CN103518724B (en) | Bactericidal composition containing fluopyram and methoxyacrylate | |
CN104137836B (en) | A kind of bactericidal composition of fluorine-containing azoles bacterium aniline and methoxy acrylic | |
CN104126585B (en) | A kind of combination sterilization composition of fluorine-containing azoles bacterium aniline | |
CN105724386B (en) | A kind of bactericidal composition of Fluxapyroxad-containsterilization | |
CN104336027B (en) | A kind of composition pesticide of fluorine-containing thiazole pyrrole ethyl ketone | |
CN104285954A (en) | Efficient fungicidal composition | |
CN103371189B (en) | A kind of bactericidal composition containing antibiotic in pyrimidine nucleoside class | |
CN103535365A (en) | Bactericidal composition | |
CN104413031B (en) | A kind of compound pesticide composition of fluorine-containing ether bacterium amide | |
CN105211082B (en) | A kind of composition pesticide containing dimoxystrobin | |
CN103371187B (en) | Bactericidal composition containing antibiotic in pyrimidine nucleoside class | |
CN103416417B (en) | The fungicidal composition of a kind of fluorine-containing azoles bacterium acid amides | |
CN103518727B (en) | A kind of bactericidal composition of containing fluopyram | |
CN103478152B (en) | Fenamidone-containing sterilization composition | |
CN103416427B (en) | A kind of bactericidal composition containing tiadinil | |
CN105613520B (en) | A kind of bactericidal composition containing tiadinil | |
CN105746546B (en) | A kind of bactericidal composition of containing fluopicolide | |
CN104012556B (en) | A kind of bactericidal composition containing fluorine mepanipyrim and thiocarbamates | |
CN105900990B (en) | A kind of bactericidal composition of Quinoxyfen-containinsterilization | |
CN104106582B (en) | A kind of bactericidal composition containing chlorine nalidixic bacterium ester and thiocarbamates | |
CN104412996B (en) | A kind of high-efficient pesticide composition of fluorine-containing ether bacterium amide | |
CN105685035B (en) | A kind of bactericidal composition containing dimoxystrobin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP01 | Change in the name or title of a patent holder | ||
CP01 | Change in the name or title of a patent holder |
Address after: 715500 Pucheng Shaanxi chemical base industrial park, Shaanxi, Weinan Patentee after: Shaanxi yitianfeng crop Technology Co.,Ltd. Address before: 715500 Pucheng Shaanxi chemical base industrial park, Shaanxi, Weinan Patentee before: Shaanxi Welch Crop Protection Co.,Ltd. |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180626 |