CN105686852A - Ophthalmology diagnosis-based ultrasonic pulse excitation and echo acquisition system - Google Patents
Ophthalmology diagnosis-based ultrasonic pulse excitation and echo acquisition system Download PDFInfo
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Abstract
The invention relates to the technical field of ultrasonic imaging, and provides an ophthalmology diagnosis-based ultrasonic pulse excitation and echo acquisition system. The system includes a upper computer, a lower computer, and an ultrasonic probe; the upper computer is used for generating a control command, sending the control command to the lower computer, and receiving an ultrasonic echo signal acquired by the lower computer; the lower computer is used for receiving the control command, performing sequential control to generate a timing sequence meeting a demand of a user to control element emission and probe scanning of the ultrasonic probe, and acquiring and uploading the ultrasonic echo signal; and the ultrasonic probe is a multi-element annular array probe and is used for receiving the control command sent from the lower computer and performing element emission and probe scanning according to the control command. The ophthalmology diagnosis-based ultrasonic pulse excitation and echo acquisition system can achieve change of the acoustic beam focus depth, sampling of the eight-channel high-frequency annular array probe, and openness of data interfaces.
Description
[technical field]
The present invention relates to ultrasonic imaging technique field, particularly relate to a kind of ultrasonic pulse excitation and echo acquirement system examining survey based on ophthalmology。
[background technology]
Ophthalmology ultrasonic device main in the market, many employings unit of singly shaking carries out impulse ejection and reception, and the depth of focus of its ultrasonic acoustic beam is fixing。
In addition, each specialty ophthalmology ultrasonic device is developed manufacturer and is accessed for outside all without opening interface, so pulse echo data can not be obtained, conventional scheme is that the analogue signal of echo in ophthalmology ultrasonic instrument is acquired by Usage data collection card, but such framework has two shortcomings: first, the capture card of current main flow cannot gather the high-frequency signal up to eight passages simultaneously;Second, owing to conventional ophthalmology ultrasound machine is not increased income, it is difficult to go arrange some sequential and control parameter according to respective requirement, therefore the ophthalmology that the scheme of existing acquisition pulse echo data is difficult to be further used under scientific research purpose examines survey。And in current each laboratory, the general purpose ultrasound platform that scientific research adopts is not suitable with ophthalmology this technical specification of ultrasonic high frequency。Therefore, not yet there are the ultrasound pulse transmission being specifically designed to ophthalmology annular array probe and acquisition system in the market。
[summary of the invention]
The technical problem to be solved in the present invention is to provide a kind of ultrasonic pulse excitation and echo acquirement system examining survey based on ophthalmology, can realize the opening of the change of the sound beam focusing degree of depth, eight multi-channel high frequency ring battle array probe samplings and data-interface。
The present invention adopts the following technical scheme that
A kind of ultrasonic pulse excitation system examining survey based on ophthalmology, described system includes host computer, slave computer and ultrasonic probe;Wherein,
Described host computer is used for producing control instruction and sending to slave computer;
Described slave computer is for receiving control instruction and carrying out sequencing contro to produce to meet the sequential that user requires, to control shake in ultrasonic probe unit's transmitting and scanning probe;
Described ultrasonic probe is the ring battle array probe that shakes more, for receiving the control instruction of slave computer transmission and carrying out, according to described control instruction, first the transmitting and scanning probe that shake。
Further, described host computer includes controlling interface and host computer the first communication interface, and described control interface is for receiving the control instruction of user's input and described control instruction being passed through host computer the first communications interface transmission to slave computer;
Described slave computer includes slave computer the first communication interface, control module, PLD and transmitter module, described slave computer the first communication interface is connected with host computer the first communication interface, for receiving described control instruction and transmitting to controlling module, described control module for translating into the register controlled word of PLD by control instruction, described PLD is for receiving described register controlled word and carrying out sequencing contro to produce to meet the sequential that user requires, launched to ultrasonic probe by transmitter module to control shake in ultrasonic probe unit's transmitting and scanning probe。
Further, described slave computer also includes transmit-receive switch, signal processing module and slave computer memory module, is used for gathering ultrasound echo signal;
The side of described transmit-receive switch is connected with transmitter module and signal processing module respectively, opposite side is connected with ultrasonic probe, for switching the break-make between transmitter module-ultrasonic probe and signal processing module-ultrasonic probe, it is controlled instruction issue when transmitter module-ultrasonic probe connection, carries out echo signal reception when signal processing module-ultrasonic probe connection;
Described signal processing module is also connected with PLD, is used for the echo-signal of passback after receiving ultrasonic probe collection and carries out signal processing, transmits the echo-signal after processing to PLD;
Described slave computer memory module is connected with PLD, is used for the echo signal data stored after the process of PLD transmission。
Further, described host computer also includes host computer second communication interface and host computer memory module, for receiving the ultrasound echo signal that slave computer gathers;Described slave computer also includes slave computer second communication interface, it is connected with host computer second communication interface and PLD respectively, the echo signal data that slave computer memory module is stored by described PLD is stored to host computer memory module by slave computer second communication interface, the transmission of host computer second communication interface, it is achieved uploading of echo signal data。
Further, described host computer the first communication interface and slave computer the first communication interface are com interface。
Further, described control module is MCU or DSP, and described PLD is FPGA。
Further, described transmitter module is high pressure transmitting chip。
Further, described signal processing module is front-end filtering and modulus conversion chip。
Further, described slave computer memory module is SRAM。
Further, described slave computer also includes the probe interface for connecting ultrasonic probe。
Compared with prior art, the beneficial effects of the present invention is:
1, the present invention adopts the ring battle array of many array element to pop one's head in, the transmitting sequential of unit of being shaken by change each of which, it is possible to achieve the change of the sound beam focusing degree of depth, pops one's head in than Dan Zhenyuan, improves ultrasonic acoustic beam performance。
2, the present invention adopts the ultrasound pulse transmission of specialty and ultrasonic front-end chip, process in the transmitting of acoustic beam and the reception of echo and can reach better performance, eight channel ultrasound impulse ejections of the highest 10MHz and the echo samples rate of each passage up to 65MSPS can be realized。
3, the present invention can gather the pulse echo that in ultrasonic probe, eight units of shaking receive, and synchronize to be stored in slave computer SRAM, and these data are open to user, user only need to click " data are uploaded " button by host computer interface, system slave computer just can pass through USB interface and be uploaded in system host computer by the echo signal data collected in SRAM, forming data file, user can use this data convert pulse echo, carries out imaging or signal analysis and processing。
4, the invention provides the system control interface of host computer, user only need to regulate the parameter of each command register, carries out secondary development or function upgrading, can realize the time sequence modification and control to lower computer system, drastically increase the motility of system。
[accompanying drawing explanation]
Fig. 1 is the structured flowchart of the ultrasonic pulse excitation system examining survey based on ophthalmology that the embodiment of the present invention 1 provides;
Fig. 2 is the ultrasonic pulse excitation examining survey based on ophthalmology that provides of the embodiment of the present invention 2 and the structured flowchart of echo acquirement system;
Fig. 3 is the ultrasonic pulse excitation examining survey based on ophthalmology that provides of the embodiment of the present invention 3 and the structured flowchart of echo acquirement system。
[detailed description of the invention]
In order to make the purpose of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated。Should be appreciated that specific embodiment described herein is only in order to explain the present invention, is not intended to limit the present invention。
As long as just can be mutually combined additionally, technical characteristic involved in each embodiment of invention described below does not constitute conflict each other。
Embodiment 1:
What the present embodiment provided examine the ultrasonic pulse excitation system of survey based on ophthalmology uses as the ultrasound pulse transmission platform of test probe。
As it is shown in figure 1, the embodiment of the present invention 1 provides a kind of ultrasonic pulse excitation system examining survey based on ophthalmology, this system includes host computer, slave computer and ultrasonic probe;Wherein, host computer is used for producing control instruction and sending to slave computer;Slave computer is for receiving control instruction and carrying out sequencing contro to produce to meet the sequential that user requires, to control shake in ultrasonic probe unit's transmitting and scanning probe;Ultrasonic probe is the ring battle array probe that shakes more, for receiving the control instruction of slave computer transmission and carrying out, according to control instruction, first the transmitting and scanning probe that shake。In the present embodiment, ultrasonic probe adopts eight multi-channel high frequency ring battle array probes, and the control instruction sent for receiving slave computer carries out shake unit's transmitting and scanning probe。Below the particular make-up of host computer and slave computer is described in further details:
Host computer can be common computer, it includes controlling interface and host computer the first communication interface (such as com interface), controls interface for receiving the control instruction of user's input and control instruction being passed through host computer the first communications interface transmission to slave computer。
Slave computer includes slave computer the first communication interface (such as com interface), control module and (MCU or DSP can be adopted, the present embodiment is MCU), PLD (such as FPGA) and transmitter module (such as high pressure transmitting chip), slave computer the first communication interface is connected with host computer the first communication interface, for receiving control instruction and transmitting to controlling module, control module for control instruction being translated into the register controlled word of PLD, PLD is for receiving register control word and carries out sequencing contro to produce to meet the sequential that user requires, launched to ultrasonic probe by transmitter module to control shake in ultrasonic probe unit's transmitting and scanning probe。High pressure transmitting chip, can realize multichannel ultrasound pulse transmission, and according to impedance matching circuit corresponding to probe performance adjustment, obtains good high-frequency and high-voltage excitation waveform。This slave computer also includes the probe interface for connecting ultrasonic probe, and probe interface side connects transmitter module, and opposite side connects ultrasonic probe。
The present embodiment is operated by the host computer interface of system, the com interface that can control host computer sends corresponding control word or data to control the MCU of slave computer, MCU is by translating these control words and data, form corresponding FPGA register data, it is input in the depositor of FPGA, these depositors represent the information such as the time delay of each transmission channel, frequency, enable, FPGA is according to the content in these depositors, give the high frequency ultrasound impulse ejection that eight transmission channels are corresponding respectively, to change the transmitting pulse concentration degree of depth and the acoustic beam characteristic of ophthalmology annular array probe。The FPGA of slave computer sends transmitting pulse excitation signal by high pressure transmitting chip, it often launches primary emission pulse excitation signal, just can control the motor of ultrasonic probe to operate a step, make motor that high frequency ring battle array probe can be driven to carry out fan shape moving, to reach eyes are carried out the purpose of sector scanning imaging。
Compare ophthalmology ultrasonic device main in the market, many employings unit of singly shaking carries out impulse ejection and reception, the depth of focus of its ultrasonic acoustic beam is fixing, native system adopts the ring battle array probe of many array elements, by change each of which shake unit transmitting sequential, the change of the sound beam focusing degree of depth can be realized, pop one's head in than Dan Zhenyuan, improve ultrasonic acoustic beam performance。
Embodiment 2:
What the present embodiment provided examine the ultrasonic pulse excitation of survey based on ophthalmology and echo acquirement system can be used as the ultrasound pulse transmission platform of test probe and uses, moreover it is possible to the pulse echo that unit of shaking in acquisition probe receives more, and synchronization is stored in slave computer memory module。Only the difference part of the present embodiment Yu embodiment 1 is described in detail below。
As shown in Figure 2, the embodiment of the present invention 2 provides a kind of ultrasonic pulse excitation and echo acquirement system examining survey based on ophthalmology, within the system, except the parts that system in embodiment 1 includes, this slave computer also includes transmit-receive switch, signal processing module (such as front-end filtering and modulus conversion chip) and slave computer memory module (such as SRAM), is used for gathering ultrasound echo signal;The side of transmit-receive switch is connected with transmitter module and signal processing module respectively, opposite side is connected with ultrasonic probe, for switching the break-make between transmitter module-ultrasonic probe and signal processing module-ultrasonic probe, it is controlled instruction issue when transmitter module-ultrasonic probe connection, carries out echo signal reception when signal processing module-ultrasonic probe connection;Signal processing module is also connected with PLD, for the echo-signal of passback after receiving ultrasonic probe collection and carry out signal processing (including the preposition amplification of low noise, time gain compensation, analog digital conversion etc.), by the echo-signal transmission after processing to PLD;Slave computer memory module is connected with PLD, is used for the echo signal data stored after the process of PLD transmission。
Time gain compensation and the analog digital conversion of multichannel ultrasonic echo can be realized at echo reception end, front-end filtering and modulus conversion chip。The present embodiment system is by adopting ultrasound pulse transmission chip (high pressure transmitting chip) and the ultrasonic front-end chip (front-end filtering and modulus conversion chip) of specialty, process in the transmitting of acoustic beam and the reception of echo and can reach better performance, it is possible to realize being up to eight channel ultrasound impulse ejections of 10MHz and the echo samples rate of each passage up to 65MSPS。
In the present embodiment, the lower computer FPGA of system is while carrying out launching impulse ejection, first echo detected that shakes to eight with starting synchronous damage-free is acquired, gather and undertaken by signal processing module, the present embodiment carries out echo wave signal acquisition by integrated 8 front-end filterings receiving passage and modulus conversion chip, the analogue signal that unit of shaking receives is carried out data acquisition and analog digital conversion with the speed being up to 65MSPS sample rate by this chip, and forming the digital signal of corresponding 12, FPGA gathers these digital signals and is stored in SRAM。
Embodiment 3:
What the present embodiment provided examine the ultrasonic pulse excitation of survey based on ophthalmology and echo acquirement system serves not only as the ultrasound pulse transmission platform of test probe and uses, the pulse echo that the interior unit of shaking of acquisition probe receives more, and synchronize to be stored in slave computer memory module, also achieve the opening of data-interface, namely uploading of echo data can be realized according to user's request。Only the difference part of the present embodiment Yu embodiment 2 is described in detail below。
As shown in Figure 3, the embodiment of the present invention 3 provides a kind of ultrasonic pulse excitation and echo acquirement system examining survey based on ophthalmology, within the system, except the parts that system in embodiment 2 includes, this host computer also includes host computer second communication interface (such as USB interface) and host computer memory module (hard disk of such as computer), for receiving the ultrasound echo signal that slave computer gathers;Slave computer also includes slave computer second communication interface (such as USB interface), it is connected with host computer second communication interface and PLD respectively, the echo signal data that slave computer memory module is stored by PLD is stored to host computer memory module by slave computer second communication interface, the transmission of host computer second communication interface, it is achieved uploading of echo signal data。
In the present embodiment, when echo wave signal acquisition completes, the host computer of system passes through serial ports control word, instruction MCU controls FPGA and by USB interface (USB interface for example with USB2.0 agreement), the data (in SRAM the echo signal data of storage) received is uploaded to host computer, is used for carrying out data process and imaging。
Native system can eight units of shaking receive in acquisition probe pulse echos, and synchronize to be stored in slave computer SRAM, these data are open to user, as long as user clicks " data are uploaded " button (namely by controlling interface input control signal) by host computer interface, system slave computer just can pass through USB interface and be uploaded in system host computer by the echo signal data collected in SRAM, form data file, user can use this data convert pulse echo, carries out imaging or signal analysis and processing。
The system digits signals collecting core that the present embodiment provides adopts MCU+FPGA framework, gathers the data after front-end chip analog digital conversion by high-performance FPGA, and sample frequency is the highest can reach 65MSPS, the sample requirement ultrasonic to meet ophthalmology。MCU chip is by writing control instruction to FPGA depositor, it is possible to open to PC control interface, in order to regulate the parameters of ultrasonic system, and controls the function of FPGA, it is achieved timing requirements。The data that FPGA gathers all nondestructively leave in the data buffer (FIFO, FirstInFirstOut) of first in first out parallel, and can be uploaded to host computer (computer) by USB2.0 interface。The framework of MCU+FPGA can provide and control interface flexibly, and user easily can realize the control to slave computer sequential when being unfamiliar with slave computer framework。
System Working Principle:
User produces control instruction by PC control interface, this instruction is committed to the MCU chip of slave computer by com interface, MCU chip receives this series of control instructions by com interface, and translate into the register controlled word of FPGA, then passing through the interface with FPGA and write in its depositor, FPGA carries out sequencing contro according to these register controlled words, produces to meet the sequential that user requires, control Under Ultrasonic Vibration unit to launch, and the motor controlling probe carries out the rotation of correspondence。Echo-signal is admitted to front-end chip and carries out the preposition amplification of low noise, time gain compensation, analog digital conversion after being received by eight units of shaking, and eventually forms digital signal and stores in sram, points out collection to complete to host computer immediately。By PC control interface, user informs that lower computer FPGA carries out data and uploads, the echo data that eight passages are gathered by lower computer system by USB interface transmits to host computer, completes primary emission and gatherer process。
Concrete operations example:
1, user uses USB line and serial port data line, is electrically connected by upper and lower computer, then starts slave computer。
2, user passes through PC control interface, and first hyperacoustic frequency, each communication channel delay are launched in selection, whether data are uploaded, motor runs the transmitting such as step number, segmentation and acquisition parameter, then pass through serial port data line, transfer data to slave computer。
3, after slave computer receives data, if loading parameters is complete, will returning dependent instruction to host computer, now, user just can control slave computer and carries out launching and receive。
4, echo acquirement is complete, slave computer returns to the instruction of host computer " collection completes ", user can click " data are uploaded " button, just now the echo data gathered will pass through USB2.0 agreement, it is uploaded in host computer, forming one and be available for the data file that upper computer software reads and operates, user can be read out by matlab or VC++, and does imaging algorithm or other operations。
User can not also use the data acquisition function of this system, the direct ultrasound pulse transmission platform (system that similar embodiment 1 provides) using lower computer system as a test probe, only need to cancel the option of " data are uploaded " in user interface, when lower computer system runs, echo-signal will not be acquired。
In addition, the present invention adopts MCU+FPGA framework, sequential and the operation note of many keys has been secured due to FPGA, system is also provided by the system control interface of host computer, user only need to regulate the parameter of each command register, carry out secondary development or function upgrading, the time sequence modification and control to lower computer system can be realized, drastically increase the motility of system。Such as have only to change the numerical value in depositor, it is possible to control lower computer system neatly and carry out various sequence change, it is achieved different user's requests;The user interface of host computer is write based on VC++ environment, in such circumstances, it is possible to add according to user's request or delete corresponding functional block or button, as long as corresponding corresponding depositor carries out parameter modification, lower computer system just can be made to realize corresponding function upgrading, etc.。
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all any amendment, equivalent replacement and improvement etc. made within the spirit and principles in the present invention, should be included within protection scope of the present invention。
Claims (10)
1. the ultrasonic pulse excitation system examining survey based on ophthalmology, it is characterised in that described system includes host computer, slave computer and ultrasonic probe;Wherein,
Described host computer is used for producing control instruction and sending to slave computer;
Described slave computer is for receiving control instruction and carrying out sequencing contro to produce to meet the sequential that user requires, to control shake in ultrasonic probe unit's transmitting and scanning probe;
Described ultrasonic probe is the ring battle array probe that shakes more, for receiving the control instruction of slave computer transmission and carrying out, according to described control instruction, first the transmitting and scanning probe that shake。
2. the system as claimed in claim 1, it is characterized in that, described host computer includes controlling interface and host computer the first communication interface, and described control interface is for receiving the control instruction of user's input and described control instruction being passed through host computer the first communications interface transmission to slave computer;
Described slave computer includes slave computer the first communication interface, control module, PLD and transmitter module, described slave computer the first communication interface is connected with host computer the first communication interface, for receiving described control instruction and transmitting to controlling module, described control module for translating into the register controlled word of PLD by control instruction, described PLD is for receiving described register controlled word and carrying out sequencing contro to produce to meet the sequential that user requires, launched to ultrasonic probe by transmitter module to control shake in ultrasonic probe unit's transmitting and scanning probe。
3. system as claimed in claim 2, it is characterised in that described slave computer also includes transmit-receive switch, signal processing module and slave computer memory module, is used for gathering ultrasound echo signal;
The side of described transmit-receive switch is connected with transmitter module and signal processing module respectively, opposite side is connected with ultrasonic probe, for switching the break-make between transmitter module-ultrasonic probe and signal processing module-ultrasonic probe, it is controlled instruction issue when transmitter module-ultrasonic probe connection, carries out echo signal reception when signal processing module-ultrasonic probe connection;
Described signal processing module is also connected with PLD, is used for the echo-signal of passback after receiving ultrasonic probe collection and carries out signal processing, transmits the echo-signal after processing to PLD;
Described slave computer memory module is connected with PLD, is used for the echo signal data stored after the process of PLD transmission。
4. system as claimed in claim 3, it is characterised in that described host computer also includes host computer second communication interface and host computer memory module, for receiving the ultrasound echo signal that slave computer gathers;Described slave computer also includes slave computer second communication interface, it is connected with host computer second communication interface and PLD respectively, the echo signal data that slave computer memory module is stored by described PLD is stored to host computer memory module by slave computer second communication interface, the transmission of host computer second communication interface, it is achieved uploading of echo signal data。
5. the system as described in any one of claim 2-4, it is characterised in that described host computer the first communication interface and slave computer the first communication interface are com interface。
6. the system as described in any one of claim 2-4, it is characterised in that described control module is MCU or DSP, described PLD is FPGA。
7. the system as described in any one of claim 2-4, it is characterised in that described transmitter module is high pressure transmitting chip。
8. the system as described in claim 3 or 4, it is characterised in that described signal processing module is front-end filtering and modulus conversion chip。
9. the system as described in claim 3 or 4, it is characterised in that described slave computer memory module is SRAM。
10. the system as described in any one of claim 1-4, it is characterised in that described slave computer also includes the probe interface for connecting ultrasonic probe。
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