CN105648004B - Preparation method of dasyatis akajei cartilage antioxidative collagen peptide - Google Patents
Preparation method of dasyatis akajei cartilage antioxidative collagen peptide Download PDFInfo
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- CN105648004B CN105648004B CN201511014856.5A CN201511014856A CN105648004B CN 105648004 B CN105648004 B CN 105648004B CN 201511014856 A CN201511014856 A CN 201511014856A CN 105648004 B CN105648004 B CN 105648004B
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- 102000008186 Collagen Human genes 0.000 title claims abstract description 52
- 108010035532 Collagen Proteins 0.000 title claims abstract description 52
- 229920001436 collagen Polymers 0.000 title claims abstract description 52
- 241001430386 Dasyatis akajei Species 0.000 title claims abstract description 48
- 210000000845 cartilage Anatomy 0.000 title claims abstract description 46
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 30
- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
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- HHEAADYXPMHMCT-UHFFFAOYSA-N dpph Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1[N]N(C=1C=CC=CC=1)C1=CC=CC=C1 HHEAADYXPMHMCT-UHFFFAOYSA-N 0.000 abstract description 2
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- OHDRQQURAXLVGJ-HLVWOLMTSA-N azane;(2e)-3-ethyl-2-[(e)-(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazinylidene]-1,3-benzothiazole-6-sulfonic acid Chemical compound [NH4+].[NH4+].S/1C2=CC(S([O-])(=O)=O)=CC=C2N(CC)C\1=N/N=C1/SC2=CC(S([O-])(=O)=O)=CC=C2N1CC OHDRQQURAXLVGJ-HLVWOLMTSA-N 0.000 abstract 1
- -1 hydroxyl radicals Chemical class 0.000 description 7
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- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
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- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 description 1
- 241000251730 Chondrichthyes Species 0.000 description 1
- SOEATRRYCIPEHA-BQBZGAKWSA-N Gly-Glu-Glu Chemical compound [H]NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O SOEATRRYCIPEHA-BQBZGAKWSA-N 0.000 description 1
- HKSNHPVETYYJBK-LAEOZQHASA-N Gly-Ile-Glu Chemical compound CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)CN HKSNHPVETYYJBK-LAEOZQHASA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- AJHCSUXXECOXOY-UHFFFAOYSA-N N-glycyl-L-tryptophan Natural products C1=CC=C2C(CC(NC(=O)CN)C(O)=O)=CNC2=C1 AJHCSUXXECOXOY-UHFFFAOYSA-N 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
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- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
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- 230000004097 bone metabolism Effects 0.000 description 1
- 230000011382 collagen catabolic process Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN201511014856.5A CN105648004B (en) | 2015-12-31 | 2015-12-31 | Preparation method of dasyatis akajei cartilage antioxidative collagen peptide |
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CN201511014856.5A CN105648004B (en) | 2015-12-31 | 2015-12-31 | Preparation method of dasyatis akajei cartilage antioxidative collagen peptide |
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CN105648004A CN105648004A (en) | 2016-06-08 |
CN105648004B true CN105648004B (en) | 2020-09-08 |
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CN201511014856.5A Active CN105648004B (en) | 2015-12-31 | 2015-12-31 | Preparation method of dasyatis akajei cartilage antioxidative collagen peptide |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106244659A (en) * | 2016-10-26 | 2016-12-21 | 内蒙古蒙肽生物工程有限公司 | The method of preparation poultry Cartilage collagen polypeptide |
CN107936113B (en) * | 2017-12-12 | 2020-11-10 | 浙江海洋大学 | Mullet scale iron chelating peptide and preparation method thereof |
CN114106151A (en) * | 2021-12-10 | 2022-03-01 | 中基惠诚科技有限公司 | Preparation method of antioxidant active collagen peptide |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103204904A (en) * | 2013-02-01 | 2013-07-17 | 浙江海洋学院 | Dasyatis akajei chondroprotein polypeptide capable of resisting prostate cancer, and preparation method and application thereof |
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2015
- 2015-12-31 CN CN201511014856.5A patent/CN105648004B/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103204904A (en) * | 2013-02-01 | 2013-07-17 | 浙江海洋学院 | Dasyatis akajei chondroprotein polypeptide capable of resisting prostate cancer, and preparation method and application thereof |
Non-Patent Citations (3)
Title |
---|
Influence of average molecular weight on antioxidant and functional properties of cartilage collagen hydrolysates from Sphyrna lewini, Dasyatis akjei and Raja porosa;Zhongrui Li等;《Food Research International》;20131231;第51卷;摘要,正文第284页左栏第2,6-7段 * |
Isolation and characterization of collagen from the cartilages of brownbanded bamboo shark (Chiloscyllium punctatum) and blacktip shark (Carcharhinus limbatus);Phanat Kittiphattanabawon等;《LWT-Food Science and Technology》;20100630;第43卷(第5期);792-800 * |
孔鳐软骨多肽及泥蚶多肽的制备及活性研究;胡发远;《中国优秀硕士学位论文全文数据库 工程科技I辑》;20151015(第10期);摘要,正文实验方法、结果分析和结语与展望部分 * |
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TR01 | Transfer of patent right |
Effective date of registration: 20211108 Address after: 100000 4 floor 4009, 3 building, 30 Shixing street, Shijingshan District, Beijing. Patentee after: BEIJING SIMEITOL BIOTECHNOLOGY Co.,Ltd. Address before: 230000 room 2406, block C, Jiaqiao International Plaza, Baohe District, Hefei City, Anhui Province Patentee before: Hefei little hedgehog Information Technology Co.,Ltd. Effective date of registration: 20211108 Address after: 230000 room 2406, block C, Jiaqiao International Plaza, Baohe District, Hefei City, Anhui Province Patentee after: Hefei little hedgehog Information Technology Co.,Ltd. Address before: 316022 Zhoushan City, Zhejiang Province No. 1, Haida South Road, Changzhi Island, Lincheng street, Zhoushan City, Zhejiang Province Patentee before: ZHEJIANG OCEAN University |
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TR01 | Transfer of patent right | ||
CB03 | Change of inventor or designer information |
Inventor after: Xu Ximing Inventor after: Xu Yuming Inventor after: Gong Jianhui Inventor after: Xu Yinfeng Inventor after: Wang Bin Inventor after: Sun Kunlai Inventor after: Yang Fan Inventor before: Xu Yinfeng Inventor before: Wang Bin Inventor before: Sun Kunlai Inventor before: Yang Fan |
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CB03 | Change of inventor or designer information |