CN105641510A - Traditional Chinese medicine composition for treating child obliterans bronchiolitis - Google Patents

Traditional Chinese medicine composition for treating child obliterans bronchiolitis Download PDF

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CN105641510A
CN105641510A CN201610023790.4A CN201610023790A CN105641510A CN 105641510 A CN105641510 A CN 105641510A CN 201610023790 A CN201610023790 A CN 201610023790A CN 105641510 A CN105641510 A CN 105641510A
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parts
herba
radix
fructus
chinese medicine
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李蕾
顾峰
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Affiliated Hospital of University of Qingdao
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Abstract

The invention discloses a traditional Chinese medicine composition for treating child obliterans bronchiolitis. The traditional Chinese medicine composition is prepared from, by weight, 10 parts of radix gentianae, 10 parts of herba cepbalanoplosis segeti, 10 parts of nodus nelumbinis rhizomatis charcoal, 5 parts of cortex eucommiae, 6 parts of cuttle bones, 5 parts of bamboo juice, 7 parts of kusnezoff monkshood roots, 12 parts of eggplant calyxes, 15 parts of Chinese banana roots, 7 parts of herb of acronychia pedunculata, 5 parts of radix acanthopanacis semticosi, 6 parts of herba euonymi, 7 parts of herba rabdosiae, 5 parts of fructus rubi, 10 parts of rhizoma belamcandae, 5 parts of stigma croci, 10 parts of herba pteridis multifidae, 5 parts of smallflower milkwort herb with roots, 10 parts of radix ilicis asprellae, 5 parts of henry clematis roots, 3 parts of tender branches of myricaria bracteata, 3 parts of herba veronicae linariifoliae, 5 parts of polyporus umbellatus, 10 parts of semen oroxyli, 15 parts of rhizoma curculiginis, 10 parts of fructus persicae immaturus, 10 parts of herb of veronica linariifolia Pall. ex Link, 12 parts of spanishneedles herb, 10 parts of leaves of mallotus barbatus, 10 parts of herba dianthi, 7 parts of fructus quisqualis, 7 parts of squama manis, 15 parts of akebia stems, 8 parts of Taiwan beautyberry leaves, 15 parts of herba geranii, 10 parts of fructus bruceae and 5 parts of rhizoma nardostachyos. According to the traditional Chinese medicine composition for treating the child obliterans bronchiolitis, all the traditional Chinese medicinal materials jointly achieve the effects of freeing the lung and relieving asthma, clearing heat and promoting diuresis, relieving the sore throat and moistening the lung and the like through syndrome differentiation compatibility, and the treatment effect on obliterans bronchiolitis patients is significant.

Description

A kind of Chinese medicine composition treating child's occlusive bronchiolitis
Technical field
The present invention relates to a kind of Chinese medicine composition treating child's occlusive bronchiolitis.
Background technology
Bronchiolar case is blocked as far back as German pathologist Lange first report 1 example new granulation tissue in 1901, and by its called after occlusive bronchiolitis. From pathology angle, occlusive bronchiolitis is defined as two kinds of bronchial damage: i.e. stenosis bronchiolitis and proliferative bronchitis, and the former is chronic inflammatory disease in various degree or Fibrotic obstruction, the latter and in tube chamber fibrosis change. Being mainly property of clinical manifestation is coughed slowly, dyspnea, PET, and can because of later respiratory tract infection exacerbation of symptoms. Occlusive bronchiolitis confirms to change by case, but lung bioplsy differs and gets diseased region surely, and clinical practice is restricted. High resolution ct, pulmonary function test have its specific findings, can as the foundation of clinical diagnosis. The treatment of occlusive bronchiolitis includes many aspects, there is no the treatment criterion that the whole world is generally acknowledged at present. Its prognosis is different with the weight difference of clinical manifestation.
Child's occlusive bronchiolitis is generally secondary to lower respiratory infection, and viral infection is the most common. The infection childhood period that Epidemiological study showing is the high risk factor in the future developing into asthma and chronic obstructive pulmonary disease. After recent Childhood Viral, the study on large sample of occlusive bronchiolitis shows, adenovirus infection is less than 3 years old Child Development is the high risk factor of occlusive bronchiolitis after infecting. The occlusive bronchiolitis patient doing virusology detection have 71% to turn out to be adenovirus infection. Infect the order of severity of the type of adenovirus, quantity and the character of host, immunoreation and environmental factors and acute phase of disease and being related closely of complication at a specified future date. Report that maximum is 3,7,21 type adenoviruss. Cause the inflammation of the damage of capillary bronchial epithelial cell and upper sub-dermal structures during the generation of occlusive bronchiolitis due to adenovirus infection after adenovirus infection, and what the improper reparation of above inflammation and damage was caused by body.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating child's occlusive bronchiolitis.
The adopted technical solution is that:
A kind of Chinese medicine composition treating child's occlusive bronchiolitis, it is made up of the raw material of Chinese medicine of following weight parts proportioning: Radix Gentianae 10-15, Herba Cirsii 7-18, charred Nodus Nelumbinis Rhizomatis 5-15, Cortex Eucommiae 2-15, Os Sepiae 5-10, Succus Bambusae 2-10, Radix Aconiti Kusnezoffii 5-10, Calyx Solani melongenae 10-15, Radix Musae 10-20, Lignum Dalbergiae Odoriferae 5-12, Radix Et Caulis Acanthopanacis Senticosi 3-15, Caulis Seu Folium Euonymi Fortunei 5-10, Rabdosia rubescens 5-10, Fructus Rubi 3-15, Rhizoma Belamcandae 5-20, Stigma Croci 3-10, Herba Pteridis Multifidae 5-15, Herba Polygalae Telephioidis 5-15, Radix Ilicis Asprellae 5-15, Radix Clematidis Henryi 5-15, father-in-law ripple 2-10, HERBA VERONICAE DILATATAE 3-15, Polyporus 2-10, Semen Oroxyli 5-15, Rhizoma Curculiginis 10-20, Fructus Pruni persicae immaturus 5-15, ZHUIFENGCAO 5-15, Herba Bidentis Bipinnatae 10-15, Folium Malloti barbati 5-20, Herba Dianthi 5-15, Fructus Quisqualis 5-10, Squama Manis 5-10, Caulis Akebiae 10-20, Folium Callicarpae Formosanae 5-10, Herba Erodii 10-20, Fructus Bruceae 5-15, Radix Et Rhizoma Nardostachyos 3-10.
Preferably, the weight of each raw material of Chinese medicine is: Radix Gentianae 10, Herba Cirsii 10, charred Nodus Nelumbinis Rhizomatis 10, the Cortex Eucommiae 5, Os Sepiae 6, Succus Bambusae 5, Radix Aconiti Kusnezoffii 7, Calyx Solani melongenae 12, Radix Musae 15, Lignum Dalbergiae Odoriferae 7, Radix Et Caulis Acanthopanacis Senticosi 5, Caulis Seu Folium Euonymi Fortunei 6, Rabdosia rubescens 7, Fructus Rubi 5, Rhizoma Belamcandae 10, Stigma Croci 5, Herba Pteridis Multifidae 10, Herba Polygalae Telephioidis 5, Radix Ilicis Asprellae 10, Radix Clematidis Henryi 5, father-in-law's ripple 3, HERBA VERONICAE DILATATAE 3, Polyporus 5, Semen Oroxyli 10, Rhizoma Curculiginis 15, Fructus Pruni persicae immaturus 10, ZHUIFENGCAO 10, Herba Bidentis Bipinnatae 12, Folium Malloti barbati 10, Herba Dianthi 10, Fructus Quisqualis 7, Squama Manis 7, Caulis Akebiae 15, Folium Callicarpae Formosanae 8, Herba Erodii 15, Fructus Bruceae 10, Radix Et Rhizoma Nardostachyos 5.
Above-mentioned Chinese medicine composition can prepare into decoction, and preparation method is as follows: the raw material of Chinese medicine of above-mentioned weight portion is put into drug-decocting appliance, soaks half an hour, and amount of water is advisable to exceed liquid level 2-3cm; Then boil with high heat, after boiling 10 minutes, then use slow fire instead and decoct stopping in 30 minutes, remove medicinal residues, take decoction.
Pharmacology and the effect of the present invention are as follows:
Primary disease belongs to the categories such as Chinese medicine " cough " " asthma " " phlegm retention ". diseases caused by exogenous pathogenic factor are many by wind, caused by heresy criminal's lung of cold, summer-heat, wet, dry, fiery six climate exopathogens, patient because lungs are weak or spleen deficiency generating phlegm, flaming up of liver-fire, asthenia of renal qi etc. involve in lung, then belongs to internal injury and causes a disease. the present invention chooses Radix Gentianae targetedly, Herba Cirsii, charred Nodus Nelumbinis Rhizomatis, the Cortex Eucommiae, Os Sepiae, Succus Bambusae, Radix Aconiti Kusnezoffii, Calyx Solani melongenae, Radix Musae, Lignum Dalbergiae Odoriferae, Radix Et Caulis Acanthopanacis Senticosi, Caulis Seu Folium Euonymi Fortunei, Rabdosia rubescens, Fructus Rubi, Rhizoma Belamcandae, Stigma Croci, Herba Pteridis Multifidae, Herba Polygalae Telephioidis, Radix Ilicis Asprellae, Radix Clematidis Henryi, Weng Bo, HERBA VERONICAE DILATATAE, Polyporus, Semen Oroxyli, Rhizoma Curculiginis, Fructus Pruni persicae immaturus, ZHUIFENGCAO, Herba Bidentis Bipinnatae, Folium Malloti barbati, Herba Dianthi, Fructus Quisqualis, Squama Manis, Caulis Akebiae, Folium Callicarpae Formosanae, Herba Erodii, Fructus Bruceae, Radix Et Rhizoma Nardostachyos is totally 37 taste raw material of Chinese medicine.
Wherein: Radix Gentianae, heat clearing and damp drying, eliminating pathogen in the liver is calmed the frightened.
Herba Cirsii, cooling blood for hemostasis, promoting blood circulation and detoxication.
Charred Nodus Nelumbinis Rhizomatis, astringing to arrest bleeding;
The Cortex Eucommiae, tool invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.
Os Sepiae, relieving gastric hyperacidity to alleviate stomachache, hemostasis.
Succus Bambusae, the fire of the lung stomach that can clear away heart-fire, there is eliminating phlegm to moisturize, the effect of arresting convulsion.
Radix Aconiti Kusnezoffii, expelling wind and removing dampness, dispersing cold for relieving pain.
Calyx Solani melongenae, has removing heat from blood, effect of removing toxic substances.
Radix Musae, has heat clearing away, quenches the thirst, diuresis, effect of removing toxic substances.
Lignum Dalbergiae Odoriferae, has multiple biological activity, can ease pain, stops blooding, antibacterial, antiinflammatory.
Radix Et Caulis Acanthopanacis Senticosi, wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, endocrine regulation dysfunction.
Caulis Seu Folium Euonymi Fortunei, relaxing muscles and tendons and activating QI and blood in the collateral, stop blooding repercussive.
Rabdosia rubescens, has anti-inflammatory analgetic, an effect that stomach invigorating is invigorated blood circulation.
Fructus Rubi, has supplementing the kidney to control the nocturnal reducing urination, effect of nourishing the liver to improve visual acuity.
Rhizoma Belamcandae, can heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm.
Stigma Croci, invigorates blood circulation, blood stasis dispelling, pain relieving.
Herba Pteridis Multifidae, has the effects such as clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, subduing swelling and detoxicating.
Herba Polygalae Telephioidis, cough-relieving, removing food stagnancy, promoting blood circulation to remove blood stasis.
Radix Ilicis Asprellae, heat clearing away, promote the production of body fluid, invigorate blood circulation, removing toxic substances.
Radix Clematidis Henryi, promoting flow of QI and blood, anti-inflammation, pain relieving.
Weng Bo, yang invigorating is dispersed; Removing toxic substances rash; Dispelling wind for relieving itching.
HERBA VERONICAE DILATATAE, has lung heat clearing, reduces phlegm, cough-relieving, the effect of removing toxic substances.
Polyporus, has diuresis to harness the river swollen effect.
Semen Oroxyli, sore-throat relieving lung moistening; Dispersing the stagnated liver-QI for regulating the stomach; Expelling pus and promoting granulation.
Rhizoma Curculiginis, has the effect of reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and promoting the circulation of blood detumescence.
Fructus Pruni persicae immaturus, arresting sweating, hemostasis, pain relieving.
ZHUIFENGCAO, has sensible effect of inducing sweat.
Herba Bidentis Bipinnatae, has effect of heat-clearing and toxic substances removing, removing blood stasis and activating blood flow.
Folium Malloti barbati, has thermal detoxification; Dampness removing to stop itchin; Effect of cooling blood for hemostasis.
Herba Dianthi, has heat clearing away, diuresis, removing blood stasis to stimulate the menstrual flow effect.
Fructus Quisqualis, removing food stagnancy, spleen invigorating, parasite killing relieving constipation.
Squama Manis, blood circulation promoting and dispersing pathogen accumulation; Stimulate the menstrual flow stimulating milk secretion; Eliminating carbuncle is burst hard.
Caulis Akebiae, diuretic, heat clearing away, lactogenesis.
Folium Callicarpae Formosanae, astringing to arrest bleeding; Heat-clearing and toxic substances removing.
Herba Erodii, removing dampness and detoxicating, restrain granulation promoting.
Fructus Bruceae, for the mature seed of quassia Fel Anas domestica subtree. For controlling dysentery, malaria.
Radix Et Rhizoma Nardostachyos, regulating QI to relieve pain, activating spleen and strengthening stomach.
Full side compatibility, plays the effects such as depressed lung-energy dispersing, clearing away heat-damp and promoting diuresis, sore-throat relieving lung moistening altogether, and occlusive Children with Bronchiolitis therapeutic effect is notable.
Clinical data
1, basic document
Select the occlusive bronchiolitis patient 200 example clinical observation made a definite diagnosis. It is randomly divided into treatment group and matched group two groups, treatment group 100 example, matched group 100 example. Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparability.
2, Therapeutic Method
Matched group: adopt bromhexine hydrochloride, child is administered orally: 4-8mg/ time, 3 times on the one.
Treatment group: on treatment of control group basis, takes decoction of the present invention, oral, every day 2 times, each 1 time sooner or later, each 50-100ml; Within 7 days, it is 1 course for the treatment of, uses 2-3 the course for the treatment of continuously.
3, efficacy assessment standard
Cure: symptom all disappears, and physical recovery is normal.
Effective: symptom substantially alleviates, health takes a turn for the better to some extent.
Effective: symptom alleviates to some extent, health takes a turn for the better to some extent.
Invalid: by symptom after treating without alleviating or increasing the weight of.
4, therapeutic outcome
Treatment group: cure 59 examples, effective 28 examples, effective 13 examples, invalid 0 example, cure rate 59%, total effective rate 100%.
Matched group: cure 28 examples, effective 22 examples, effective 16 examples, invalid 34 examples, cure rate 28%, total effective rate 66%.
Result above shows, the cure rate for the treatment of group and total effective rate, obviously higher than matched group, illustrate that Chinese medicine composition of the present invention is notable to occlusive bronchiolitis child patient therapeutic effect, are worth further clinical expansion.
Detailed description of the invention
Embodiment 1
Each raw material of Chinese medicine is weighed by following weight:
Radix Gentianae 10, Herba Cirsii 10, charred Nodus Nelumbinis Rhizomatis 10, the Cortex Eucommiae 5, Os Sepiae 6, Succus Bambusae 5, Radix Aconiti Kusnezoffii 7, Calyx Solani melongenae 12, Radix Musae 15, Lignum Dalbergiae Odoriferae 7, Radix Et Caulis Acanthopanacis Senticosi 5, Caulis Seu Folium Euonymi Fortunei 6, Rabdosia rubescens 7, Fructus Rubi 5, Rhizoma Belamcandae 10, Stigma Croci 5, Herba Pteridis Multifidae 10, Herba Polygalae Telephioidis 5, Radix Ilicis Asprellae 10, Radix Clematidis Henryi 5, father-in-law's ripple 3, HERBA VERONICAE DILATATAE 3, Polyporus 5, Semen Oroxyli 10, Rhizoma Curculiginis 15, Fructus Pruni persicae immaturus 10, ZHUIFENGCAO 10, Herba Bidentis Bipinnatae 12, Folium Malloti barbati 10, Herba Dianthi 10, Fructus Quisqualis 7, Squama Manis 7, Caulis Akebiae 15, Folium Callicarpae Formosanae 8, Herba Erodii 15, Fructus Bruceae 10, Radix Et Rhizoma Nardostachyos 5.
The raw material of Chinese medicine of above-mentioned weight portion being put into drug-decocting appliance, soaks half an hour, amount of water is advisable to exceed liquid level 2-3cm; Then boil with high heat, after boiling 10 minutes, then use slow fire instead and decoct stopping in 30 minutes, remove medicinal residues, take decoction.
Embodiment 2
Each raw material of Chinese medicine is weighed by following weight:
Radix Gentianae 10, Herba Cirsii 18, charred Nodus Nelumbinis Rhizomatis 5, the Cortex Eucommiae 15, Os Sepiae 5, Succus Bambusae 2, Radix Aconiti Kusnezoffii 10, Calyx Solani melongenae 10, Radix Musae 20, Lignum Dalbergiae Odoriferae 12, Radix Et Caulis Acanthopanacis Senticosi 3, Caulis Seu Folium Euonymi Fortunei 5, Rabdosia rubescens 10, Fructus Rubi 3, Rhizoma Belamcandae 20, Stigma Croci 3, Herba Pteridis Multifidae 15, Herba Polygalae Telephioidis 5, Radix Ilicis Asprellae 15, Radix Clematidis Henryi 15, father-in-law's ripple 2, HERBA VERONICAE DILATATAE 3, Polyporus 10, Semen Oroxyli 5, Rhizoma Curculiginis 10, Fructus Pruni persicae immaturus 15, ZHUIFENGCAO 5, Herba Bidentis Bipinnatae 10, Folium Malloti barbati 20, Herba Dianthi 5, Fructus Quisqualis 10, Squama Manis 5, Caulis Akebiae 20, Folium Callicarpae Formosanae 5, Herba Erodii 10, Fructus Bruceae 15, Radix Et Rhizoma Nardostachyos 3.
The raw material of Chinese medicine of above-mentioned weight portion being put into drug-decocting appliance, soaks half an hour, amount of water is advisable to exceed liquid level 2-3cm; Then boil with high heat, after boiling 10 minutes, then use slow fire instead and decoct stopping in 30 minutes, remove medicinal residues, take decoction.
Embodiment 3
Each raw material of Chinese medicine is weighed by following weight:
Radix Gentianae 15, Herba Cirsii 7, charred Nodus Nelumbinis Rhizomatis 15, the Cortex Eucommiae 2, Os Sepiae 10, Succus Bambusae 10, Radix Aconiti Kusnezoffii 5, Calyx Solani melongenae 15, Radix Musae 10, Lignum Dalbergiae Odoriferae 5, Radix Et Caulis Acanthopanacis Senticosi 15, Caulis Seu Folium Euonymi Fortunei 10, Rabdosia rubescens 5, Fructus Rubi 15, Rhizoma Belamcandae 5, Stigma Croci 10, Herba Pteridis Multifidae 5, Herba Polygalae Telephioidis 15, Radix Ilicis Asprellae 5, Radix Clematidis Henryi 5, father-in-law's ripple 10, HERBA VERONICAE DILATATAE 15, Polyporus 2, Semen Oroxyli 15, Rhizoma Curculiginis 20, Fructus Pruni persicae immaturus 5, ZHUIFENGCAO 15, Herba Bidentis Bipinnatae 15, Folium Malloti barbati 5, Herba Dianthi 15, Fructus Quisqualis 5, Squama Manis 10, Caulis Akebiae 10, Folium Callicarpae Formosanae 10, Herba Erodii 20, Fructus Bruceae 5, Radix Et Rhizoma Nardostachyos 10.
The raw material of Chinese medicine of above-mentioned weight portion being put into drug-decocting appliance, soaks half an hour, amount of water is advisable to exceed liquid level 2-3cm; Then boil with high heat, after boiling 10 minutes, then use slow fire instead and decoct stopping in 30 minutes, remove medicinal residues, take decoction.

Claims (2)

1. the Chinese medicine composition treating child's occlusive bronchiolitis, it is characterized in that it is made up of the raw material of Chinese medicine of following weight parts proportioning: Radix Gentianae 10-15, Herba Cirsii 7-18, charred Nodus Nelumbinis Rhizomatis 5-15, Cortex Eucommiae 2-15, Os Sepiae 5-10, Succus Bambusae 2-10, Radix Aconiti Kusnezoffii 5-10, Calyx Solani melongenae 10-15, Radix Musae 10-20, Lignum Dalbergiae Odoriferae 5-12, Radix Et Caulis Acanthopanacis Senticosi 3-15, Caulis Seu Folium Euonymi Fortunei 5-10, Rabdosia rubescens 5-10, Fructus Rubi 3-15, Rhizoma Belamcandae 5-20, Stigma Croci 3-10, Herba Pteridis Multifidae 5-15, Herba Polygalae Telephioidis 5-15, Radix Ilicis Asprellae 5-15, Radix Clematidis Henryi 5-15, father-in-law ripple 2-10, HERBA VERONICAE DILATATAE 3-15, Polyporus 2-10, Semen Oroxyli 5-15, Rhizoma Curculiginis 10-20, Fructus Pruni persicae immaturus 5-15, ZHUIFENGCAO 5-15, Herba Bidentis Bipinnatae 10-15, Folium Malloti barbati 5-20, Herba Dianthi 5-15, Fructus Quisqualis 5-10, Squama Manis 5-10, Caulis Akebiae 10-20, Folium Callicarpae Formosanae 5-10, Herba Erodii 10-20, Fructus Bruceae 5-15, Radix Et Rhizoma Nardostachyos 3-10.
2. a kind of Chinese medicine composition treating child's occlusive bronchiolitis according to claim 1, it is characterized in that the weight of each raw material of Chinese medicine is: Radix Gentianae 10, Herba Cirsii 10, charred Nodus Nelumbinis Rhizomatis 10, the Cortex Eucommiae 5, Os Sepiae 6, Succus Bambusae 5, Radix Aconiti Kusnezoffii 7, Calyx Solani melongenae 12, Radix Musae 15, Lignum Dalbergiae Odoriferae 7, Radix Et Caulis Acanthopanacis Senticosi 5, Caulis Seu Folium Euonymi Fortunei 6, Rabdosia rubescens 7, Fructus Rubi 5, Rhizoma Belamcandae 10, Stigma Croci 5, Herba Pteridis Multifidae 10, Herba Polygalae Telephioidis 5, Radix Ilicis Asprellae 10, Radix Clematidis Henryi 5, father-in-law's ripple 3, HERBA VERONICAE DILATATAE 3, Polyporus 5, Semen Oroxyli 10, Rhizoma Curculiginis 15, Fructus Pruni persicae immaturus 10, ZHUIFENGCAO 10, Herba Bidentis Bipinnatae 12, Folium Malloti barbati 10, Herba Dianthi 10, Fructus Quisqualis 7, Squama Manis 7, Caulis Akebiae 15, Folium Callicarpae Formosanae 8, Herba Erodii 15, Fructus Bruceae 10, Radix Et Rhizoma Nardostachyos 5.
CN201610023790.4A 2016-01-14 2016-01-14 Traditional Chinese medicine composition for treating child obliterans bronchiolitis Pending CN105641510A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105213870A (en) * 2015-11-10 2016-01-06 张在芬 A kind of Chinese medicine composition for the treatment of chronic bronchitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105213870A (en) * 2015-11-10 2016-01-06 张在芬 A kind of Chinese medicine composition for the treatment of chronic bronchitis

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Application publication date: 20160608