CN105617325A - 一种治疗家禽痢疾的中药组合物及其制备方法 - Google Patents
一种治疗家禽痢疾的中药组合物及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种治疗家禽痢疾的中药组合物及其制备方法,治疗家禽痢疾的中药组合物按照重量的原料包括:八角茴香、艾叶、鬼针草、了哥王、焦山楂、金银花、金桃娘叶、蒲公英、地榆、穿金莲、炮姜、番石榴叶、秦皮、椿根皮、黄岑、白头翁、甘草、桂枝、云木香、络石藤。本发明组方合理,制备简单,中药组合物无污染、无毒副作用、无药残、无耐药性,成本低,取材广,生物利用度高,清热解毒、凉血止痢、杀菌抑菌、行气温里止痛、提高免疫力,标本兼治,达到很好的治疗痢疾的效果;临床应用证明,本发明对治疗家禽痢疾有特效,并且使其产品肉质达到无公害要求,满足产品的出口标准,有效保证了人们的身体健康。
Description
技术领域
本发明涉及兽药技术领域,具体是一种治疗家禽痢疾的中药组合物及其制备方法。
背景技术
随着国民生活水平的提高,家禽市场的需求量越来越大,养家禽的人也越来越多,我国是饲养家禽的大国,由于饲料家禽的卫生环境差、饲养方法不当等诸多原因,造成家禽生病的现象也普遍增多,每年家禽痢疾的发病率及极高,特别是饲养基地的传染性快,如不及时治疗可导致禽类大批量死亡,在家禽的各种疾病中,尤属痢疾、腹泻最为普遍,目前治疗禽类拉痢疾的主要药物有喹乙醇片、痢菌净、敌菌净、痢特灵、氟哌酸、庆增安、痢菌克星、顶锋、尖锋、黄金二号、先锋九号等。上述西药均有治疗痢疾的作用,且止泻快,但对于较重的肠道感染性疾病,尤其是痢疾,往往出现反复,在治疗禽类方面易造成大量死亡,并且往往还会带来抗药性、耐药力作用,在家禽养殖中常因无治疗家禽痢疾的特效药造成大片家禽死亡;即便治愈,也会由于西药药物残留较重,抗生素的药物不易排除体外,易引起禽类肠道菌群紊乱、厌食等,影响禽类的产蛋、产仔,而且还影响人类使用禽肉品和蛋品的安全性。药物残留不仅可以直接对人体产生急性、慢性毒性作用,引起细菌耐药性的增加,还可以通过环境和食物链的作用直接对人体健康造成潜在危害,甚或影响我国养殖业的发展。因此在家禽的饲养业中,很需要一种疗效好、治疗时间短、成本低的治疗家禽痢疾病的药物。
发明内容
本发明的目的在于提供一种成本低、治疗时间短的治疗家禽痢疾的中药组合物及其制备方法,以解决上述背景技术中提出的问题。
为实现上述目的,本发明提供如下技术方案:
一种治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香30-40份、艾叶30-40份、鬼针草30-40份、了哥王20-40份、焦山楂20-30份、金银花20-30份、金桃娘叶15-20份、蒲公英15-20份、地榆10-20份、穿金莲10-20份、炮姜10-20份、番石榴叶10-15份、秦皮10-15份、椿根皮5-10份、黄岑5-10份、白头翁5-10份、甘草5-9份、桂枝3-9份、云木香4-8份、络石藤3-7份。
作为本发明进一步的方案:所述治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香32-38份、艾叶32-38份、鬼针草32-38份、了哥王25-35份、焦山楂22-28份、金银花22-28份、金桃娘叶16-19份、蒲公英16-19份、地榆12-18份、穿金莲12-18份、炮姜12-18份、番石榴叶11-14份、秦皮11-14份、椿根皮6-9份、黄岑6-9份、白头翁6-9份、甘草6-8份、桂枝6-8份、云木香5-7份、络石藤4-6份。
作为本发明再进一步的方案:所述治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香35份、艾叶35份、鬼针草35份、了哥王30份、焦山楂25份、金银花25份、金桃娘叶18份、蒲公英18份、地榆15份、穿金莲15份、炮姜15份、番石榴叶12份、秦皮12份、椿根皮8份、黄岑8份、白头翁8份、甘草7份、桂枝7份、云木香6份、络石藤5份。
所述治疗家禽痢疾的中药组合物的制备方法,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍40-44h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加10-14倍量水,煎煮1-2h,分离药液;
(4)将步骤(3)所得药渣再加10-12倍量水,煎煮1-2h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用100-200目筛滤过,用管式高速离心机以14000-16000r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
与现有技术相比,本发明的有益效果是:
本发明组方合理,制备简单,中药组合物无污染、无毒副作用、无药残、无耐药性,成本低,取材广,生物利用度高,清热解毒、凉血止痢、杀菌抑菌、行气温里止痛、提高免疫力,标本兼治,达到很好的治疗痢疾的效果;临床应用证明,本发明对治疗家禽痢疾有特效,并且使其产品肉质达到无公害要求,满足产品的出口标准,有效保证了人们的身体健康。
具体实施方式
下面结合具体实施方式对本专利的技术方案作进一步详细地说明。
实施例1
一种治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香30份、艾叶30份、鬼针草30份、了哥王20份、焦山楂20份、金银花20份、金桃娘叶15份、蒲公英15份、地榆10份、穿金莲10份、炮姜10份、番石榴叶10份、秦皮10份、椿根皮5份、黄岑5份、白头翁5份、甘草5份、桂枝3份、云木香4份、络石藤3份。
所述治疗家禽痢疾的中药组合物的制备方法,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍40h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加10倍量水,煎煮1h,分离药液;
(4)将步骤(3)所得药渣再加10倍量水,煎煮1h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用100目筛滤过,用管式高速离心机以14000r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
实施例2
一种治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香32份、艾叶32份、鬼针草32份、了哥王25份、焦山楂22份、金银花22份、金桃娘叶16份、蒲公英16份、地榆12份、穿金莲12份、炮姜12份、番石榴叶11份、秦皮11份、椿根皮6份、黄岑6份、白头翁6份、甘草6份、桂枝6份、云木香5份、络石藤4份。
所述治疗家禽痢疾的中药组合物的制备方法,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍41h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加11倍量水,煎煮1.2h,分离药液;
(4)将步骤(3)所得药渣再加10.5倍量水,煎煮1.2h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用120目筛滤过,用管式高速离心机以14500r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
实施例3
一种疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香35份、艾叶35份、鬼针草35份、了哥王30份、焦山楂25份、金银花25份、金桃娘叶18份、蒲公英18份、地榆15份、穿金莲15份、炮姜15份、番石榴叶12份、秦皮12份、椿根皮8份、黄岑8份、白头翁8份、甘草7份、桂枝7份、云木香6份、络石藤5份。
所述治疗家禽痢疾的中药组合物的制备方法,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍42h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加12倍量水,煎煮1.5h,分离药液;
(4)将步骤(3)所得药渣再加11倍量水,煎煮1.5h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用150目筛滤过,用管式高速离心机以15000r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
实施例4
一种治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香38份、艾叶38份、鬼针草38份、了哥王35份、焦山楂28份、金银花28份、金桃娘叶19份、蒲公英19份、地榆18份、穿金莲18份、炮姜18份、番石榴叶14份、秦皮14份、椿根皮9份、黄岑9份、白头翁9份、甘草8份、桂枝8份、云木香7份、络石藤6份。
所述治疗家禽痢疾的中药组合物的制备方法,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍43h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加13倍量水,煎煮1.8h,分离药液;
(4)将步骤(3)所得药渣再加11.5倍量水,煎煮1.8h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用180目筛滤过,用管式高速离心机以15500r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
实施例5
一种治疗家禽痢疾的中药组合物,按照重量份的原料包括:八角茴香40份、艾叶40份、鬼针草40份、了哥王40份、焦山楂30份、金银花30份、金桃娘叶20份、蒲公英20份、地榆20份、穿金莲20份、炮姜20份、番石榴叶15份、秦皮15份、椿根皮10份、黄岑10份、白头翁10份、甘草9份、桂枝9份、云木香8份、络石藤7份。
所述治疗家禽痢疾的中药组合物的制备方法,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍44h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加14倍量水,煎煮2h,分离药液;
(4)将步骤(3)所得药渣再加12倍量水,煎煮2h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用200目筛滤过,用管式高速离心机以16000r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
本发明组方合理,制备简单,中药组合物无污染、无毒副作用、无药残、无耐药性,成本低,取材广,生物利用度高,清热解毒、凉血止痢、杀菌抑菌、行气温里止痛、提高免疫力,标本兼治,达到很好的治疗痢疾的效果;临床应用证明,本发明对治疗家禽痢疾有特效,并且使其产品肉质达到无公害要求,满足产品的出口标准,有效保证了人们的身体健康。
上面对本专利的较佳实施方式作了详细说明,但是本专利并不限于上述实施方式,在本领域的普通技术人员所具备的知识范围内,还可以在不脱离本专利宗旨的前提下作出各种变化。
Claims (4)
1.一种治疗家禽痢疾的中药组合物,其特征在于,按照重量份的原料包括:八角茴香30-40份、艾叶30-40份、鬼针草30-40份、了哥王20-40份、焦山楂20-30份、金银花20-30份、金桃娘叶15-20份、蒲公英15-20份、地榆10-20份、穿金莲10-20份、炮姜10-20份、番石榴叶10-15份、秦皮10-15份、椿根皮5-10份、黄岑5-10份、白头翁5-10份、甘草5-9份、桂枝3-9份、云木香4-8份、络石藤3-7份。
2.根据权利要求1所述的治疗家禽痢疾的中药组合物,其特征在于,按照重量份的原料包括:八角茴香32-38份、艾叶32-38份、鬼针草32-38份、了哥王25-35份、焦山楂22-28份、金银花22-28份、金桃娘叶16-19份、蒲公英16-19份、地榆12-18份、穿金莲12-18份、炮姜12-18份、番石榴叶11-14份、秦皮11-14份、椿根皮6-9份、黄岑6-9份、白头翁6-9份、甘草6-8份、桂枝6-8份、云木香5-7份、络石藤4-6份。
3.根据权利要求1所述的治疗家禽痢疾的中药组合物,其特征在于,按照重量份的原料包括:八角茴香35份、艾叶35份、鬼针草35份、了哥王30份、焦山楂25份、金银花25份、金桃娘叶18份、蒲公英18份、地榆15份、穿金莲15份、炮姜15份、番石榴叶12份、秦皮12份、椿根皮8份、黄岑8份、白头翁8份、甘草7份、桂枝7份、云木香6份、络石藤5份。
4.一种如权利要求1-3任一所述的治疗家禽痢疾的中药组合物的制备方法,其特征在于,具体步骤如下:
(1)按照重量份称取各原料;
(2)将各原料药粉碎成粗粉,按渗漉法提取,用70%乙醇作溶剂,浸渍40-44h后,以每公斤按每分钟5ml的速度缓缓渗漉,收集药材10倍重量的漉液,回收乙醇至无醇味,得醇提液和药渣,备用;
(3)将药渣再加10-14倍量水,煎煮1-2h,分离药液;
(4)将步骤(3)所得药渣再加10-12倍量水,煎煮1-2h,分离药液;
(5)将步骤(3)和步骤(4)二次煎煮液,用100-200目筛滤过,用管式高速离心机以14000-16000r/min的速度离心,得提取液;
(6)加入步骤(2)得到的醇提液,再加糊精适量,搅拌均匀,加适量蒸馏水;
(7)用100目筛滤过,滤液经喷雾干燥得粉末后,干挤制粒,得颗粒,检验,包装即成。
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CN107213257A (zh) * | 2017-06-28 | 2017-09-29 | 宁国市仙之居家庭农场 | 一种治疗禽类痢疾病的中药组合物及其制备方法 |
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CN107213257A (zh) * | 2017-06-28 | 2017-09-29 | 宁国市仙之居家庭农场 | 一种治疗禽类痢疾病的中药组合物及其制备方法 |
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