CN105616741A - Traditional Chinese medicine patch for treating rheumatic arthritis and preparation method thereof - Google Patents
Traditional Chinese medicine patch for treating rheumatic arthritis and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
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- A61K9/20—Pills, tablets, discs, rods
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating rheumatic arthritis, which is characterized by comprising the following raw materials in parts by weight: 20-40 parts of sabia discolor dunn, 10-20 parts of jasminum lanceolarium, 10-20 parts of caesalpinia minax, 5-10 parts of cissus hexangularis, 5-10 parts of ardisia punctata, 2-5 parts of bulbiferous woodnettle root, 0.5-2 parts of ichnocarpus oliganthous and 0.5-2 parts of menthol. The traditional Chinese medicine preparation for treating rheumatic arthritis is quick and effective, low in cost and free of toxic or side effect, has the effects on eliminating swelling and alleviating pain, dispelling wind and eliminating dampness, nourishing the blood and promoting blood circulation, restoring menstrual flow and activating the collaterals, strengthening the bones and muscles as well as regulating the flow of qi and easing pain, and has obvious curative effects on patients suffering from rheumatic arthritis, collateral stagnation, bone pain, tendon and vessel spasm and cold pain in cloudy days.
Description
Technical field
The present invention relates to Chinese medicine preparation processing technique field, in particular to a kind of Chinese medicine preparation and its preparation method for the treatment of rheumatic arthritis.
Background technology
Rheumatic arthritis is common disease and frequently-occurring disease. Its main clinical characteristics is arthralgia, heating, joint joint stuffiness, and morning is stiff, joint deformity, the physical and mental health of serious harm patient. How not enough by human righteousness traditional Chinese medicine is thought, rheumatic arthritis belongs to " bi Zheng " category, experience wind, cold, wet, the heresy of heat and formed with muscle, muscles and bones, the pain at the places such as joint, swelling, the illness that miserable, numbness is main feature. Although the Chinese patent medicine kind of existing multiple treatment rheumatic arthritis is for selection of clinical at present, but owing to the market requirement of rheumatic arthritis medicine is very big, and western medicine this disease curative effect is undesirable, and side effect is more, though existing Chinese patent medicine kind is many, but most curative effect is not satisfactory.
Summary of the invention
It is an object of the invention to propose a kind of Chinese medicine preparation and its preparation method for the treatment of rheumatic arthritis for above-mentioned prior art deficiency; This Chinese medicine preparation fast effectively, cost low, have no side effect, there is swelling and pain relieving, dispel rheumatism, nourshing blood and promoting blood circulation, muscles and bones clearing and activating the channels and collaterals, strong, analgesic effect of regulating the flow of vital energy; For rheumatic arthritis, channels and collaterals stagnate, arthralgia, muscle arteries and veins contraction are anxious, the cloudy cold pain patient of chance has significant curative effect.
The present invention realizes by the following technical solutions:
The present invention treats the Chinese medicine preparation of rheumatic arthritis, comprises the raw material of following weight part number:
Wide rattan root 20-40 part, Jasminum lanceolarium Roxb. 10-20 part, south snake 10-20 part, root of Wingedstem Treebine 5-10 part, blood party 5-10 part, bulbiferous woodnettle root 2-5 part, Radix seu Caulis Parabarii 0.5-2 part, mentha camphor 0.5-2 part.
The Chinese medicine preparation raw material composition that the present invention treats rheumatic arthritis is preferably: wide rattan root 30-35 part, Jasminum lanceolarium Roxb. 15-18 part, south snake 15-18 part, root of Wingedstem Treebine 6-8 part, blood party 6-8 part, bulbiferous woodnettle root 3-4 part, Radix seu Caulis Parabarii 1-2 part, mentha camphor 1-2 part.
The Chinese medicine preparation raw material composition that the present invention treats rheumatic arthritis is more preferably: wide rattan root 35 parts, Jasminum lanceolarium Roxb. 15 parts, south snake 15 parts, root of Wingedstem Treebine 8 parts, blood party 8 parts, bulbiferous woodnettle root 3 parts, Radix seu Caulis Parabarii 1 part, mentha camphor 1 part.
The effective ingredient analysis of the formula of Chinese materia medica preparation of above-described treatment rheumatic arthritis:
Wide rattan root, [another name] Vernonia parishii Hook�� F��; [Latin] SabiadiscolorDunn. is root and the stem of Sabiaceae plant ass back of the body Caulis Sinomenii. [nature and flavor]: sweet; Bitter; Flat. [function cures mainly]: dispel rheumatism; Promoting blood circulation and stopping pain. Main treating rheumatic ostealgia; Fall and beat internal lesion caused by overexertion; Hepatitis.
Jasminum lanceolarium Roxb., [another name] light Jasminum lanceolarium Roxb., Jasminum lanceolarium, root or stem of Lanceolate Jasmine, broken rattan wind; [Latin] JasminumlanceolariumRoxb. is the stem of Oleaceae gelsemium plant fragrance rattan, originates in the ground such as China Guangxi, Guangdong, Yunnan, Guizhou, Sichuan. [function cures mainly]: dispel rheumatism, promoting blood circulation and stopping pain. Cure mainly rheumatism waist condyle pain, wound, fracture, sore poison etc.
South snake, [another name] Stem of Oriental Bittersweet, Semen Caesalpiniae Minacis, ram's horn, [Latin] CaesalpiniaminaxHance. is pulse family Caesalpinia beak pod mysorethorn, is used as medicine with root, stem, leaf and seed. [meridian distribution of property and flavor] root, stem, leaf: bitter, cool. [function cures mainly] root, stem, leaf: clearing away summer heat, detumescence, pain relieving, antipruritic. For cold, fever, rheumatic arthritis; Wound is controlled in external application, fracture, sore swollen toxin, skin pruritus, venomous snake bite.
Root of Wingedstem Treebine, [another name] square-stem Herba Lycopodii, wing stem white powder rattan; [Latin] CissushexangularisThorelexPlanch. is Vitaceae white powder Calamus plant root of Wingedstem Treebine, is used as medicine with rattan. [nature and flavor]: micro-hardship, cool. [function cures mainly] dispelling, collateral-activating, removing blood stasis and activating blood flow. For rheumatic arthritis, lumbar muscle strain, wound.
Blood party, [another name] pearl lid umbrella, Jia Xue party; [Latin] ArdisiapunctataLindl. [Tinuspunc-tataO.Kuntze; BladhiapunctataNakai]. it is root or the complete stool of platymiscium mountain, Myrsinacea Japanese Ardisia Herb blood pellet. [nature and flavor]: bitter, pungent, flat. [function cures mainly] dispels rheumatism, promoting blood flow to regulate menstruation, swelling and pain relieving. Cure mainly rheumatic arthralgia, dysmenorrhoea, through closing. Wound, swelling and pain in the throat. 1. " Guangxi book on Chinese herbal medicine a collection of selected materials ": " invigorate blood circulation scold through, stimulate the circulation of the blood and cause the muscles and joints to relax. Cure mainly anaemia, paralysis, menoxenia, dysmenorrhoea. Through closing, phoenix arthritis with fixed pain caused by dampness carbuncle, wound. "
Bulbiferous woodnettle root, [another name] bulbiferous woodnettle root, China Chinese mugwort fiber crops grass, red standing grain snippings, iron scale thallium, flourishing fiber crops. [Latin] Laporteabulblfera (Sieb.etZucc.) Wedd. is the root of contrayerva bulbil Chinese mugwort fiber crops. [nature and flavor] are pungent; Warm in nature. [curing mainly] dispels rheumatism; Promoting blood circulation and stopping pain. Cure mainly rheumatic arthralgia; Numb limbs and tense tendons; Wound; Fracture pain; Menoxenia; Internal lesion caused by overexertion is weak; Nephritic edema.
Radix seu Caulis Parabarii, [another name] eucommia vine, root or stem of Smallflower Parabarium, the soil bark of eucommia, the white bark of eucommia, soft Qiang rattan, knot clothing rattan, white glue rattan. [latin name] Parabariummicranthum. is stem skin and the Gen Pi of Apocynaceae eucommia vine platymiscium eucommia vine, Radix seu Caulis Parabarii rattan and hair eucommia vine, or the dry bark of flower hide glue Calamus flower hide glue rattan, mainly containing chemical compositions such as alkaloid, phenols, organic acid, carbohydrate, flavones. Radix seu Caulis Parabarii medicinal material can treat treating rheumatic ostealgia, fracture, traumatic hemorrhage etc.
Mentha camphor, is extracted by the leaf of peppermint and stem, is the main component in peppermint and Europe Peppermint essential oil. Pharmaceutically be used as excitants, external application can anti-inflammatory, pain relieving, antipruritic, stimulate circulation, alleviate edema etc.; For oral administration so that compound preparation can be alleviated local inflammation (pharyngolaryngitis) and treatment flu, and have stomach invigorating, drive wind effect.
The preparation method that the present invention treats the Chinese medicine preparation of rheumatic arthritis made by above-mentioned each component medicine:
Take in proportion wide rattan root, Jasminum lanceolarium Roxb., south snake, root of Wingedstem Treebine, blood party, bulbiferous woodnettle root pulverize into 100 object fine powders with Radix seu Caulis Parabarii, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor, concentrated, adding appropriate conventional auxiliary material, preparation process makes Chinese medicine preparation routinely.
The above Chinese medicine preparation formulation comprises pill, capsule, tablet or granule.
The above-mentioned Chinese medicine of the present invention, according to different situations and pharmaceutical factory condition, it is also possible to make other external preparation.
The Chinese medicine preparation of above-described treatment rheumatic arthritis may be used for treatment rheumatic arthritis, channels and collaterals stagnate, arthralgia, muscle arteries and veins contraction are anxious, meets cloudy cold pain patient etc.
The invention has the beneficial effects as follows:
1, the raw material of the present invention is conventional herbal medicine, wide material sources, and price is cheap; Formula of medicine is scientific and reasonable, act synergistically between each component, swelling and pain relieving can be reached, dispel rheumatism, nourshing blood and promoting blood circulation, muscles and bones clearing and activating the channels and collaterals, strong, analgesic effect of regulating the flow of vital energy, be used for the treatment of rheumatic arthritis, channels and collaterals stagnate, arthralgia, muscle arteries and veins contraction are anxious, meet the diseases such as cloudy cold pain patient, curative effect is definite, has instant effect, an advantage that result for the treatment of is good.
2, use all can be fully recovered or alleviating pain for 5-10 days of the present invention, has efficiency to reach more than 90%, to human non-toxic's side effect, it may also be useful to convenient, cost is with low.
Embodiment
Embodiment 1:
The Chinese medicine preparation preparation method of described treatment rheumatic arthritis:
Take wide rattan root 20 parts, Jasminum lanceolarium Roxb. 10 parts, south snake 10 parts, root of Wingedstem Treebine 5 parts, blood party 5 parts, bulbiferous woodnettle root 2 parts pulverize into 100 object fine powders with Radix seu Caulis Parabarii 0.5 part, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor 0.5 part, concentrated, adding appropriate dextrin, preparation process makes pill routinely.
Embodiment 2:
The Chinese medicine preparation preparation method of described treatment rheumatic arthritis:
Take wide rattan root 40 parts, Jasminum lanceolarium Roxb. 20 parts, south snake 20 parts, root of Wingedstem Treebine 10 parts, blood party 10 parts, bulbiferous woodnettle root 5 parts pulverize into 100 object fine powders with Radix seu Caulis Parabarii 2 parts, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor 2 parts, concentrated, adding appropriate starch, preparation process makes capsule routinely.
Embodiment 3:
The Chinese medicine preparation preparation method of described treatment rheumatic arthritis:
Take wide rattan root 30 parts, Jasminum lanceolarium Roxb. 12 parts, south snake 12 parts, root of Wingedstem Treebine 6 parts, blood party 6 parts, bulbiferous woodnettle root 3 parts pulverize into 100 object fine powders with Radix seu Caulis Parabarii 1.5 parts, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor 1.2 parts, concentrated, adding appropriate sucrose, preparation process makes granule routinely.
Embodiment 4:
The Chinese medicine preparation preparation method of described treatment rheumatic arthritis:
Take wide rattan root 25 parts, Jasminum lanceolarium Roxb. 18 parts, south snake 18 parts, root of Wingedstem Treebine 9 parts, blood party 9 parts, bulbiferous woodnettle root 4 parts pulverize into 100 object fine powders with Radix seu Caulis Parabarii 1.8 parts, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor 1.8 parts, concentrated, adding appropriate Magnesium Stearate, preparation process makes tablet routinely.
Embodiment 5:
The Chinese medicine preparation preparation method of described treatment rheumatic arthritis:
Take wide rattan root 35 parts, Jasminum lanceolarium Roxb. 15 parts, south snake 15 parts, root of Wingedstem Treebine 8 parts, blood party 8 parts, bulbiferous woodnettle root 3 parts pulverize into 100 object fine powders with Radix seu Caulis Parabarii 1 part, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor 1 part, concentrated, adding appropriate sucrose, preparation process makes granule routinely.
Clinical therapeutic efficacy:
In order to show that medicine of the present invention is to the result for the treatment of of rheumatic arthritis, has carried out following clinical experiment, since 2013, treat rheumatic arthritis patient 150 example altogether, wherein the male sex 85 example, women 65 example, minimum 5 years old of age, maximum 75 years old. In these patients accepted for medical treatment except 11 example trouble rheumatic arthritis are relatively more serious, most patients takes the Chinese medicine preparation of the present invention, within 5-15 days, all can fully recover or alleviating pain, have efficiency to reach more than 90%.
Model case:
Case 1, not so-and-so, man, 53 years old, suffer from rheumatic arthritis for many years, knee joint swells and ache, handicapped, take the capsule of the present invention, every day 3 times, after two courses for the treatment of of continuously coating, pain obviously alleviates, subsiding a swelling gradually, after rear continuation applies two courses for the treatment of, all symptoms disappear, and action is freely.
Case 2, Guo so-and-so, female, 55 years old, shoulder suffers from more than 2 years of rheumatic arthritis, and shoulder is not movable, and activity has obvious pain, can not bend, taking the granule of the present invention, every day 3 times, continuously coating is after 15 days, pain obviously alleviates, subsiding a swelling gradually, rear continuation applies three courses for the treatment of with consolidate curative effect, and all symptoms disappear.
Case 3, certain, man, 67 years old, suffers from rheumatic arthritis for many years, and finger, knee joint swells and ache, local presents red, swollen, scorching hot, severe pain, handicapped, through taking the pill 7 days of the present invention, alleviates pain, subside a swelling gradually, after continue to take 15 days, all diseases disappear entirely, cure.
Case 4: Lee, man, 53 years old, suffers from rheumatalgia throughout the year, and during wet weather, arthralgia cannot be walked about, it may also be useful to after tablet of the present invention, even if wet weather, rheumatism is also seldom shown effect.
Case 5: Peng so-and-so, female, 75 years old, rheumatic arthritis caused waist-leg disease health cool, difficulty in walking, and through hospitalize poor effect, through taking the pill 7 days of the present invention, pain disappears gradually, it is possible to walking, after continue to take 10 days, pain disappears, and walking is freely.
Case 6: thank certain, man, 36 years old, rheumatic arthritis illness 3 years, during wet weather, arthralgia cannot be walked about, and through taking the capsule 3 days of the present invention, pain disappears gradually, after continue to take 5 days, all diseases disappear entirely, and walking is freely.
Case 7: Lee, female, 53 years old, suffers from rheumatic arthritis 2 years, and both legs and both hands are red and swollen, difficulty in walking, takes some Western medicine and Chinese medicine pastes system, and poor effect, alleviates pain in 5 days through taking the granule of the present invention, subside a swelling gradually, after continue to take 10 days, all diseases disappear entirely, walking freely.
Claims (5)
1. treat the Chinese medicine preparation of rheumatic arthritis for one kind, it is characterized in that, comprise the raw material of following weight part number: wide rattan root 20-40 part, Jasminum lanceolarium Roxb. 10-20 part, south snake 10-20 part, root of Wingedstem Treebine 5-10 part, blood party 5-10 part, bulbiferous woodnettle root 2-5 part, Radix seu Caulis Parabarii 0.5-2 part, mentha camphor 0.5-2 part.
2. the Chinese medicine preparation for the treatment of rheumatic arthritis according to claim 1, it is characterized in that, this Chinese medicine preparation comprises the raw material of following weight part number: wide rattan root 30-35 part, Jasminum lanceolarium Roxb. 15-18 part, south snake 15-18 part, root of Wingedstem Treebine 6-8 part, blood party 6-8 part, bulbiferous woodnettle root 3-4 part, Radix seu Caulis Parabarii 1-2 part, mentha camphor 1-2 part.
3. the Chinese medicine preparation for the treatment of rheumatic arthritis according to claim 1, it is characterized in that, this Chinese medicine preparation comprises the raw material of following weight part number: wide rattan root 35 parts, Jasminum lanceolarium Roxb. 15 parts, south snake 15 parts, root of Wingedstem Treebine 8 parts, blood party 8 parts, bulbiferous woodnettle root 3 parts, Radix seu Caulis Parabarii 1 part, mentha camphor 1 part.
4. the Chinese medicine preparation for the treatment of rheumatic arthritis according to claim 1-3, it is characterized in that: described external application paste preparation method: take wide rattan root in proportion, Jasminum lanceolarium Roxb., south snake, root of Wingedstem Treebine, blood party, bulbiferous woodnettle root pulverizes into 100 object fine powders with Radix seu Caulis Parabarii, mix, pour in pithos and soak 30 minutes, add the water yield be medicine gross weight 2-10 doubly, heated and boiled 60-120 minute, when fluid temperature is down to 30-60 DEG C, filter, filter in night and add mentha camphor, concentrated, add appropriate conventional auxiliary material, preparation process makes Chinese medicine preparation routinely.
5. the Chinese medicine preparation for the treatment of rheumatic arthritis according to claim 4, it is characterised in that: described Chinese medicine preparation formulation comprises pill, capsule, tablet or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610215347.7A CN105616741A (en) | 2016-04-08 | 2016-04-08 | Traditional Chinese medicine patch for treating rheumatic arthritis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610215347.7A CN105616741A (en) | 2016-04-08 | 2016-04-08 | Traditional Chinese medicine patch for treating rheumatic arthritis and preparation method thereof |
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| CN105616741A true CN105616741A (en) | 2016-06-01 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1839952A (en) * | 2005-12-22 | 2006-10-04 | 清华大学深圳研究生院 | Traditional Chinese medicine for treating rheumatic and rheumatoid arthritis |
| CN104922443A (en) * | 2015-07-08 | 2015-09-23 | 安徽老同桌生物科技有限公司 | External-use patch for treating rheumatic arthritis |
-
2016
- 2016-04-08 CN CN201610215347.7A patent/CN105616741A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1839952A (en) * | 2005-12-22 | 2006-10-04 | 清华大学深圳研究生院 | Traditional Chinese medicine for treating rheumatic and rheumatoid arthritis |
| CN104922443A (en) * | 2015-07-08 | 2015-09-23 | 安徽老同桌生物科技有限公司 | External-use patch for treating rheumatic arthritis |
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Application publication date: 20160601 |