CN105616336A - Naturally sourced composite moisturizing agent - Google Patents
Naturally sourced composite moisturizing agent Download PDFInfo
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- CN105616336A CN105616336A CN201510933852.0A CN201510933852A CN105616336A CN 105616336 A CN105616336 A CN 105616336A CN 201510933852 A CN201510933852 A CN 201510933852A CN 105616336 A CN105616336 A CN 105616336A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
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- Tropical Medicine & Parasitology (AREA)
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Abstract
The invention discloses a naturally sourced composite moisturizing agent. A formula of the naturally sourced composite moisturizing agent comprises: in percentage by weight, glycerin, 1, 3-propanediol, 1, 3-butanediol, sodium hyaluronate, polyglutamic acid, a lactobacillus fermentation product, natural extractive and natural spring water. Raw materials for composite moisturizing composition cover the shortage of existing moisturizing raw materials, all alcohol moisturizing agents in the raw materials are from natural fermentation, all the ingredients are pure naturally sourced, and no preservatives are added, so that the composite moisturizing agent is safe and nonirritating, and compared with existing moisturizing raw materials, the composite moisturizing agent has not only good moisturizing effect, but also additional effects of promoting cell regeneration, accelerating skin metabolism, resisting bacterial and inflammation, improving rough skin, activating epidermic cells, repairing pigmentation and the like.
Description
Technical field
The present invention relates to the compound moisture-keeping composition of natural origin.
Background technology
The development trend of world today's cosmetics is to advocate green, natural, safety and environmental protection, and has certain both effectiveness. Increasing consumer wish Cosmetic Manufacture business can develop more natural, without antiseptical skin care item so that skin is more healthy. Therefore, develop natural gentleness and there is the moisture retention component materials of multiple efficacies have become as necessary to cosmetics new product development.
Summary of the invention
It is an object of the invention to provide a kind of composite humectant, and substitute traditional alcohols wetting agent with it, it is provided that than the effect not available for the better moistening effect of traditional alcohols wetting agent and traditional alcohols wetting agent.
The present invention is achieved in that the composite humectant of a kind of natural origin, and it is characterized in that the percentage by weight of this composite humectant formula consists of:
The composite humectant of described a kind of natural origin, it is characterized in that described lactobacillus fermentation product is at least one in lactobacillus/lotus seed tunning filtrate, lactobacillus/rye (Secale cereale L.) fine powder tunning, lactobacillus fermentation product and lactobacillus fermentation lysate.
The composite humectant of described a kind of natural origin, it is characterized in that described natural extract is at least one in Folium Psidii Guajavae extract, Flos Chrysanthemi extract, Fructus Momordicae charantiae berry extract, Folium Mori extract, natural ossein and peony root extractive.
The composite humectant of described a kind of natural origin, it is characterized in that described natural mineral water includes at least one in Jizhou Island Volcanic Thermal Spring water, Alps glacial water, A Lewaer thermal water, France's gold mountain range thermal water and Canada's glacier sea mud mineral water.
The composite humectant of described a kind of natural origin, it is characterized in that the glycerol in described raw material, 1,3-PD, 1,3 butylene glycol are natural fermented sources.
A kind of composite humectant all the components pure natural source of natural origin, without preservative, wherein alcohols wetting agent is all from natural fermented, do not only have moistening effect, and have promotion cell regeneration, accelerate skin metabolism, antimicrobial antiphlogistic disease, improve coarse skin, activate epidermis cell, repair the additional benefit such as pigmentation.
The glycerol contained in technical solution of the present invention is formed by animal oil or vegetable oils and fats and fat splitting culture propagation, can as skin moisturizer, hair conditioner etc.; 1,3-PD is to be formed by natural corn fermentation, has skin-moisturizing, skin effect; 1,3 butylene glycol is to be formed by fermentation by Petiolus Trachycarpi oil, Semen Maydis wet goods natural oil, and the 1,3 butylene glycol in natural fermented source has good moistening effect and is easily absorbed by the skin, to human body skin low toxicity low irritant.
The hyaluronate sodium contained in technical solution of the present invention and polyglutamic acid have lock water moisture-keeping function, and skin can be made to continue water profit. Polyglutamic acid is sticking amino acid polymer, can be prepared by fermentable, and skin can be made to moisten for a long time, can also increase skin elasticity simultaneously, reduces skin wrinkle, promotes the skin absorption to nutritional labeling.
Containing lactobacillus fermentation product in technical solution of the present invention. Lactobacillus/lotus seed tunning filtrate has reparation pigmentation, accelerates skin metabolism, improves coarse skin, effect of activation epidermis cell; Fermentation lactobacillus/rye (Secale cereale L.) fines product is the rye (Secale cereale L.) fine powder by high shell content with selected lactobacillus strains to be produced through Patent Organism fermentation technique and obtains, for having significant antibacterial effect to acne, the dandruff, antibacterial that allergic eczema is relevant, the inflammation parameter of acne skin can not only be reduced, it is also possible to improve overall health of skin.
Containing various natural extracts in technical solution of the present invention. Natural ossein can supplement the nutrient needed for skin layer, improves Skin Cell living environment and promotes the metabolism of skin histology; The extracts such as Folium Psidii Guajavae extract, Flos Chrysanthemi extract, Fructus Momordicae charantiae berry extract, Folium Mori extract all have antibacterial and bacteriostasis, can as the natural antiseptic agent of this natural composite humectant. There are some researches show that antibacterial is had stronger inhibitory action by balsam pear extract, 18.75mg/mL is reached to colibacillary minimum inhibitory concentration (MIC) is low, and its MIC low 9.375mg/mL that reaches especially to bacillus subtilis, under comparable sodium, the inhibitory action of antibacterial is better than potassium sorbate by balsam pear extract; Folium Mori extract has good anticorrosion, whitening, moistening effect, can extensive use in cosmetics; Folium Psidii Guajavae extract has stronger broad-spectrum antibacterial effect, to staphylococcus aureus, escherichia coli, meningococcus, Candida albicans, Pseudomonas aeruginosa bacteriostatic activity relatively strong, inhibition zone > 15.5m; In addition Flos Chrysanthemi extract also has antiinflammatory antioxidative effect.
The natural mineral water contained in technical solution of the present invention includes at least one in Jizhou Island Volcanic Thermal Spring water, Alps glacial water, A Lewaer thermal water, France's gold mountain range thermal water, Canada's glacier sea mud mineral water. Containing mineral such as abundant radon, hydrogen sulfide, silicate, carbonate, zinc, fluorine, iodine, manganese, silicon, copper, calcium, magnesium in mineral water, these mineral are all the necessary elements of human body, it is possible to maintain the health status that skin is best. Radon can promote the collagenic supersession of body to reduce, and prevents internal fibroblast proliferation, thus the effect that cicatrix of skin suppresses can be played; Appropriate fluorine can reduce generation and the accumulation of body lipofuscin, improves the oxidation resistance of body, has defying age and the effect of protection blood vessel; Body skin has good washing by silicon, disappear and the effectiveness such as cleaning; Zinc has obvious action in skin care, and it can promote skin elastic force fibroblast and collagen fiber to be formed and regeneration, keeps skin elasticity, promotes skin tender moist; The copper contained in mineral spring also has the important function maintaining skin health, if lacking copper will affect body to the absorption of ferrum and utilization, thus cause xerosis cutis, coarse.
Accompanying drawing explanation
Fig. 1 is the present inventor's fibroblast toxotest chart.
Fig. 2 is the present inventor's keratinocyte toxotest chart.
Fig. 3 is TNF-�� inflammatory factor test resolution of the present invention.
Fig. 4 is COX-2 inflammatory factor test resolution of the present invention.
Fig. 5 is IL-1 �� inflammatory factor test resolution of the present invention.
Fig. 6 is present invention degree of insulation test resolution.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
A kind of composite humectant of natural origin, the percentage by weight of its formula consists of:
A phase:
B phase:
Fermentation lactobacillus/rye (Secale cereale L.) fines product 1.0%,
Peony root extractive 0.1%.
A kind of composite humectant of natural origin, it is as follows that its technique prepares concrete operations:
(1) first glycerol dispersed transparent matter acid sodium and polyglutamic acid with natural fermented source is standby;
(2) adding in agitated kettle by A Lewaer thermal water, heating, to 75 DEG C, adds A phase constituent while stirring, and insulated and stirred began to cool down cooling after 5 minutes;
(3) it is cooled to 40 DEG C, B phase composition is added in agitated kettle, is uniformly mixed and can obtain final products.
Glycerol in described raw material, 1,3-propylene glycol, 1,3 butylene glycol are natural fermented sources.
Embodiment 2
A kind of composite humectant of natural origin, the percentage by weight of its formula consists of:
A phase:
B phase:
A kind of composite humectant of natural origin, it is as follows that its technique prepares concrete operations:
(1) first glycerol dispersed transparent matter acid sodium and polyglutamic acid with natural fermented source is standby;
(2) adding in agitated kettle by France's gold mountain range thermal water, heating, to 75 DEG C, adds A phase constituent while stirring, and insulated and stirred began to cool down cooling after 5 minutes;
(3) it is cooled to 40 DEG C, B phase composition is added in agitated kettle, is uniformly mixed and can obtain final products.
Embodiment 3
A kind of composite humectant of natural origin, the percentage by weight of its formula consists of:
A phase:
B phase
A kind of composite humectant of natural origin, it is as follows that its technique prepares concrete operations:
(1) first glycerol dispersed transparent matter acid sodium and polyglutamic acid with natural fermented source is standby;
(2) Jizhou Island Volcanic Thermal Spring water, Alps glacial water, A Lewaer thermal water, France's gold mountain range thermal water, Canada's glacier sea mud mineral water are added in agitated kettle, heating is to 75 DEG C, adding A phase constituent while stirring, insulated and stirred began to cool down cooling after 5 minutes;
(3) it is cooled to 40 DEG C, B phase composition is added in agitated kettle, is uniformly mixed and can obtain final products.
The composite humectant of a kind of natural origin, carries out contrast test by itself and conventional wetting agent 1,3 butylene glycol, and test result is as follows:
(1) cytotoxicity test
As shown in Figure 1 and Figure 2, by the toxotest of human fibroblasts and human keratinocyte being can be seen that the safety of this natural composite humectant is better than 1,3 butylene glycol.
(2) anti-inflammatory response test
As shown in Fig. 3, Fig. 4, Fig. 5, this natural composite humectant and 1 when to make consumption be 0.1-0.5% is can be seen that by above test result, 3-butanediol does not affect the expression of inflammatory factor TNF-��, COX-2, IL-1 ��, but when being 1.0% when making consumption, this natural composite humectant can effectively suppress the expression of inflammatory factor TNF-��, COX-2, IL-1 ��.
(3) humidity measurement is protected
As shown in Figure 6, test result can be seen that the moistening effect of skin is better than 1,3 butylene glycol by this composite humectant under comparable sodium.
Raw material sources used in the present invention are as follows
Above-described is only the preferred embodiments of the present invention. It should be pointed out that, for the person of ordinary skill of the art, without departing from the principles of the present invention, it is also possible to making some improvement and modification, this is also considered as protection scope of the present invention.
Claims (5)
1. the composite humectant of a natural origin, it is characterised in that: the percentage by weight of this composite humectant formula consists of:
The percentage by weight sum of each raw material is 100%.
2. the composite humectant of a kind of natural origin according to claim 1, it is characterised in that: described lactobacillus fermentation product is at least one in lactobacillus/lotus seed tunning filtrate, lactobacillus/rye (Secale cereale L.) fine powder tunning, lactobacillus fermentation product and lactobacillus fermentation lysate.
3. the composite humectant of a kind of natural origin according to claim 1, it is characterised in that: described natural extract is at least one in Folium Psidii Guajavae extract, Flos Chrysanthemi extract, Fructus Momordicae charantiae berry extract, Folium Mori extract, natural ossein and peony root extractive.
4. the composite humectant of a kind of natural origin according to claim 1, it is characterised in that: described natural mineral water includes at least one in Jizhou Island Volcanic Thermal Spring water, Alps glacial water, A Lewaer thermal water, France's gold mountain range thermal water and Canada's glacier sea mud mineral water.
5. the composite humectant of a kind of natural origin according to claim 1, it is characterised in that: the glycerol in described raw material, 1,3-PD, 1,3 butylene glycol are natural fermented sources.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510933852.0A CN105616336A (en) | 2015-12-14 | 2015-12-14 | Naturally sourced composite moisturizing agent |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510933852.0A CN105616336A (en) | 2015-12-14 | 2015-12-14 | Naturally sourced composite moisturizing agent |
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| CN105616336A true CN105616336A (en) | 2016-06-01 |
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| CN201510933852.0A Pending CN105616336A (en) | 2015-12-14 | 2015-12-14 | Naturally sourced composite moisturizing agent |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375049A (en) * | 2017-07-27 | 2017-11-24 | 朱思文 | One primary yeast repairs essence lotion |
| CN107485644A (en) * | 2017-08-14 | 2017-12-19 | 佛山实瑞先导材料研究院（普通合伙） | A kind of antibacterial anti-inflammatory agent and its application |
| CN107625670A (en) * | 2016-07-19 | 2018-01-26 | 黄秉炘 | Thermal water and crops fermentation skin care products processing procedure |
| CN107982158A (en) * | 2017-12-27 | 2018-05-04 | 海南卓泰制药有限公司 | A kind of sodium hyaluronate water profit stoste and preparation method thereof |
| CN109700737A (en) * | 2019-01-24 | 2019-05-03 | 合肥天一生物技术研究所有限责任公司 | A kind of plant type moisturizing is spraying and preparation method thereof |
| CN110731941A (en) * | 2018-07-02 | 2020-01-31 | 中山市泛华精细化学品有限公司 | A cosmetic containing beneficial bacteria for skin care |
| CN110974771A (en) * | 2019-12-27 | 2020-04-10 | 广州蜜妆生物科技有限公司 | Scalp care composition and application thereof |
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| CN103181862A (en) * | 2011-12-29 | 2013-07-03 | 上海媚兰生物科技发展有限公司 | Composite moisturizing agent and application thereof |
| CN103520082A (en) * | 2013-10-10 | 2014-01-22 | 深圳市金因生物技术有限公司 | Anti-aging composition containing epidermal growth factor and preparation method thereof |
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2015
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| CN103181862A (en) * | 2011-12-29 | 2013-07-03 | 上海媚兰生物科技发展有限公司 | Composite moisturizing agent and application thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625670A (en) * | 2016-07-19 | 2018-01-26 | 黄秉炘 | Thermal water and crops fermentation skin care products processing procedure |
| CN107375049A (en) * | 2017-07-27 | 2017-11-24 | 朱思文 | One primary yeast repairs essence lotion |
| CN107485644A (en) * | 2017-08-14 | 2017-12-19 | 佛山实瑞先导材料研究院（普通合伙） | A kind of antibacterial anti-inflammatory agent and its application |
| CN107982158A (en) * | 2017-12-27 | 2018-05-04 | 海南卓泰制药有限公司 | A kind of sodium hyaluronate water profit stoste and preparation method thereof |
| CN110731941A (en) * | 2018-07-02 | 2020-01-31 | 中山市泛华精细化学品有限公司 | A cosmetic containing beneficial bacteria for skin care |
| CN109700737A (en) * | 2019-01-24 | 2019-05-03 | 合肥天一生物技术研究所有限责任公司 | A kind of plant type moisturizing is spraying and preparation method thereof |
| CN110974771A (en) * | 2019-12-27 | 2020-04-10 | 广州蜜妆生物科技有限公司 | Scalp care composition and application thereof |
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