CN105601778B - 一种含有季铵基团的环状卤胺类高分子抗菌剂及其制备方法和应用 - Google Patents
一种含有季铵基团的环状卤胺类高分子抗菌剂及其制备方法和应用 Download PDFInfo
- Publication number
- CN105601778B CN105601778B CN201610035810.XA CN201610035810A CN105601778B CN 105601778 B CN105601778 B CN 105601778B CN 201610035810 A CN201610035810 A CN 201610035810A CN 105601778 B CN105601778 B CN 105601778B
- Authority
- CN
- China
- Prior art keywords
- antibacterial agent
- ring
- presoma
- polymer antibacterial
- quaternary ammonium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 101
- 229920000642 polymer Polymers 0.000 title claims abstract description 65
- -1 halogen amine Chemical class 0.000 title claims abstract description 53
- 229910052736 halogen Inorganic materials 0.000 title claims abstract description 42
- 125000001453 quaternary ammonium group Chemical group 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 239000000463 material Substances 0.000 claims abstract description 39
- 238000006243 chemical reaction Methods 0.000 claims abstract description 36
- 229920002521 macromolecule Polymers 0.000 claims abstract description 24
- 230000002421 anti-septic effect Effects 0.000 claims abstract description 22
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 22
- 230000003115 biocidal effect Effects 0.000 claims abstract description 17
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 17
- 238000003786 synthesis reaction Methods 0.000 claims abstract description 17
- 229940088710 antibiotic agent Drugs 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims abstract description 12
- 230000026030 halogenation Effects 0.000 claims abstract description 9
- 238000005658 halogenation reaction Methods 0.000 claims abstract description 9
- 238000010041 electrostatic spinning Methods 0.000 claims abstract description 5
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical class CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims abstract description 4
- 238000006467 substitution reaction Methods 0.000 claims abstract description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 34
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 24
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims description 21
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 18
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 16
- 229910052801 chlorine Inorganic materials 0.000 claims description 14
- 150000003384 small molecules Chemical class 0.000 claims description 14
- 125000001309 chloro group Chemical group Cl* 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 12
- 238000002390 rotary evaporation Methods 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 11
- 239000000460 chlorine Substances 0.000 claims description 11
- 238000000746 purification Methods 0.000 claims description 11
- 238000009987 spinning Methods 0.000 claims description 11
- 238000001035 drying Methods 0.000 claims description 10
- 239000003999 initiator Substances 0.000 claims description 8
- 239000003208 petroleum Substances 0.000 claims description 8
- 238000006116 polymerization reaction Methods 0.000 claims description 8
- 238000010792 warming Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- FKJODVFXQRXEOL-VIFPVBQESA-N C(C)(C)(C)OC([C@@H](NCCC)CCO)=O Chemical compound C(C)(C)(C)OC([C@@H](NCCC)CCO)=O FKJODVFXQRXEOL-VIFPVBQESA-N 0.000 claims description 7
- IBYHHJPAARCAIE-UHFFFAOYSA-N 1-bromo-2-chloroethane Chemical class ClCCBr IBYHHJPAARCAIE-UHFFFAOYSA-N 0.000 claims description 5
- 238000001523 electrospinning Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 239000000178 monomer Substances 0.000 claims description 5
- 230000001681 protective effect Effects 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 239000000758 substrate Substances 0.000 claims description 3
- 239000003960 organic solvent Substances 0.000 claims description 2
- 238000007348 radical reaction Methods 0.000 claims description 2
- 239000011541 reaction mixture Substances 0.000 claims description 2
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 claims 2
- QGZKDVFQNNGYKY-OUBTZVSYSA-N Ammonia-15N Chemical compound [15NH3] QGZKDVFQNNGYKY-OUBTZVSYSA-N 0.000 claims 1
- STPFYEHIOKIXQH-FVGYRXGTSA-N C(Cl)Cl.C(C)(C)(C)OC([C@@H](NCCC)CCO)=O Chemical compound C(Cl)Cl.C(C)(C)(C)OC([C@@H](NCCC)CCO)=O STPFYEHIOKIXQH-FVGYRXGTSA-N 0.000 claims 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 abstract description 17
- 231100000252 nontoxic Toxicity 0.000 abstract description 5
- 230000003000 nontoxic effect Effects 0.000 abstract description 5
- 150000002367 halogens Chemical class 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 239000002994 raw material Substances 0.000 abstract description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 30
- 239000000835 fiber Substances 0.000 description 21
- 238000005660 chlorination reaction Methods 0.000 description 16
- 238000012360 testing method Methods 0.000 description 16
- 239000000047 product Substances 0.000 description 12
- 241000894006 Bacteria Species 0.000 description 11
- 239000000523 sample Substances 0.000 description 10
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 9
- 238000003860 storage Methods 0.000 description 8
- 241000588724 Escherichia coli Species 0.000 description 7
- 238000001704 evaporation Methods 0.000 description 7
- 230000008020 evaporation Effects 0.000 description 7
- 239000002904 solvent Substances 0.000 description 7
- 241000191967 Staphylococcus aureus Species 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical compound CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 description 4
- 150000002148 esters Chemical group 0.000 description 4
- 150000008282 halocarbons Chemical class 0.000 description 4
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical group O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 241000219095 Vitis Species 0.000 description 3
- 235000009754 Vitis X bourquina Nutrition 0.000 description 3
- 235000012333 Vitis X labruscana Nutrition 0.000 description 3
- 235000014787 Vitis vinifera Nutrition 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 230000003292 diminished effect Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000007654 immersion Methods 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 239000002068 microbial inoculum Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 3
- 238000013112 stability test Methods 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- LYFQYPSHMWBHFG-UHFFFAOYSA-N 1-bromo-2-chloroethene Chemical class ClC=CBr LYFQYPSHMWBHFG-UHFFFAOYSA-N 0.000 description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
- 241001646719 Escherichia coli O157:H7 Species 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
- 229910052794 bromium Chemical group 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 244000000010 microbial pathogen Species 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- ZKQDCIXGCQPQNV-UHFFFAOYSA-N Calcium hypochlorite Chemical compound [Ca+2].Cl[O-].Cl[O-] ZKQDCIXGCQPQNV-UHFFFAOYSA-N 0.000 description 1
- QDHHCQZDFGDHMP-UHFFFAOYSA-N Chloramine Chemical class ClN QDHHCQZDFGDHMP-UHFFFAOYSA-N 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 241001333951 Escherichia coli O157 Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000005708 Sodium hypochlorite Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012496 blank sample Substances 0.000 description 1
- 150000001656 butanoic acid esters Chemical class 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 150000008422 chlorobenzenes Chemical class 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 229960004279 formaldehyde Drugs 0.000 description 1
- 235000019256 formaldehyde Nutrition 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910001507 metal halide Inorganic materials 0.000 description 1
- 150000005309 metal halides Chemical class 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002086 nanomaterial Chemical class 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 1
- CRWJEUDFKNYSBX-UHFFFAOYSA-N sodium;hypobromite Chemical compound [Na+].Br[O-] CRWJEUDFKNYSBX-UHFFFAOYSA-N 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000010148 water-pollination Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/18—Introducing halogen atoms or halogen-containing groups
- C08F8/20—Halogenation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F120/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F120/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F120/10—Esters
- C08F120/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/44—Preparation of metal salts or ammonium salts
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610035810.XA CN105601778B (zh) | 2016-01-19 | 2016-01-19 | 一种含有季铵基团的环状卤胺类高分子抗菌剂及其制备方法和应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610035810.XA CN105601778B (zh) | 2016-01-19 | 2016-01-19 | 一种含有季铵基团的环状卤胺类高分子抗菌剂及其制备方法和应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105601778A CN105601778A (zh) | 2016-05-25 |
CN105601778B true CN105601778B (zh) | 2017-07-11 |
Family
ID=55982180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610035810.XA Active CN105601778B (zh) | 2016-01-19 | 2016-01-19 | 一种含有季铵基团的环状卤胺类高分子抗菌剂及其制备方法和应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105601778B (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106359383A (zh) * | 2016-08-08 | 2017-02-01 | 山东科技大学 | 一种含双键、季铵盐和卤胺双官能杀菌剂及其制备方法和应用 |
CN106866847B (zh) * | 2017-02-17 | 2019-04-23 | 天津大学 | 含活泼氨基海因衍生物共聚材料及其制备方法 |
CN109248334A (zh) * | 2018-08-31 | 2019-01-22 | 湖南博隽生物医药有限公司 | 一种外科手术缝合线用抗菌剂及其制备方法 |
CN111118484B (zh) * | 2020-01-17 | 2021-08-17 | 中山大学附属口腔医院 | 一种钛种植体表面的长效可再生抗菌涂层 |
CN113307898B (zh) * | 2021-01-20 | 2022-08-23 | 银金达(上海)新材料有限公司 | 一种抗菌petg材料及其应用 |
CN114292354B (zh) * | 2021-11-01 | 2023-06-16 | 深圳市森若新材科技有限公司 | 一种可应用于空调蓄冷的聚合物相变材料 |
CN114438665B (zh) * | 2022-01-28 | 2023-04-25 | 广东粤港澳大湾区国家纳米科技创新研究院 | 一种抗菌无纺布及其制备方法 |
CN115340698B (zh) * | 2022-08-16 | 2023-10-27 | 常州工业职业技术学院 | 一种医用抗菌材料及其制备方法和应用 |
CN117720704B (zh) * | 2024-02-01 | 2024-05-24 | 浙江梅盛新材料有限公司 | 一种水性聚氨酯乳液及其制备方法和应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06234726A (ja) * | 1992-11-24 | 1994-08-23 | Takeda Chem Ind Ltd | 防菌・防かび性化合物、その製造法および剤 |
JP2004024418A (ja) * | 2002-06-24 | 2004-01-29 | Create Medic Co Ltd | 抗菌性組成物 |
US8658192B2 (en) * | 2007-11-19 | 2014-02-25 | University Of Washington | Integrated antimicrobial and low fouling materials |
CN100548454C (zh) * | 2007-12-19 | 2009-10-14 | 浙江大学 | 一种表面交联抗菌复合膜的制备方法 |
CN102796214A (zh) * | 2012-06-08 | 2012-11-28 | 上海师范大学 | 一类含有季铵盐和卤胺或卤胺前置体官能团的杀菌聚合物及其制备方法和应用 |
CN102786477B (zh) * | 2012-08-17 | 2014-10-29 | 上海师范大学 | 一种含有季铵盐官能团的羟基卤胺类化合物及其制备方法和应用 |
CN102875814B (zh) * | 2012-09-19 | 2016-02-03 | 光景生物科技(苏州)有限公司 | 聚硅氧烷及制备方法、用途以及含有该聚硅氧烷的杀菌剂 |
CN103061125A (zh) * | 2013-01-17 | 2013-04-24 | 江南大学 | 一种含有反应性官能团的卤胺类抗菌剂及其制备方法和应用 |
CN103193903A (zh) * | 2013-04-19 | 2013-07-10 | 上海师范大学 | 含有季铵盐和卤胺或卤胺前置体官能团的杀菌聚合物及其制备方法和应用 |
CN103276596B (zh) * | 2013-05-29 | 2015-07-01 | 上海师范大学 | 一种季铵化卤胺抗菌棉纤维的制备方法 |
CN103524652B (zh) * | 2013-09-30 | 2016-02-03 | 江南大学 | 一种含季铵盐基团的卤胺类聚合物抗菌剂及其制备方法和应用 |
CN103757906A (zh) * | 2014-02-18 | 2014-04-30 | 江南大学 | 一种含季铵基团的烯烃类卤胺化合物接枝抗菌棉织物的制备方法 |
CN103923267B (zh) * | 2014-04-14 | 2017-01-04 | 英德市雅家涂料有限公司 | 一种具有抗菌功能聚酯改性丙烯酸树脂及其制备方法 |
CN104926787A (zh) * | 2015-05-15 | 2015-09-23 | 大连理工大学 | 吡啶季铵盐型卤胺抗菌剂及其制备方法 |
-
2016
- 2016-01-19 CN CN201610035810.XA patent/CN105601778B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN105601778A (zh) | 2016-05-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105601778B (zh) | 一种含有季铵基团的环状卤胺类高分子抗菌剂及其制备方法和应用 | |
CN105613506B (zh) | 一种卤胺/季铵烯烃类抗菌剂及其在生物可降解纳米纤维材料中的应用 | |
US5104649A (en) | Surface-functionalized biocidal polymers | |
CN100554296C (zh) | 可反应性高分子抗菌剂及其制备方法和应用 | |
CN101808514B (zh) | 生物活性苯胺共聚物 | |
CN109837734B (zh) | 一种可控疏水的抗菌纤维膜及其制备方法 | |
CN109771314A (zh) | 一种长效抗、抑菌湿巾及其制备方法 | |
CN106496358A (zh) | 双亲性壳聚糖季铵盐衍生物及其制备和应用 | |
JP2021520443A (ja) | 多機能性樹脂およびその製造方法と応用 | |
CN105145566A (zh) | 一种季铵盐抗菌剂和结构型抗菌树脂 | |
CN105237668A (zh) | 一种新型高分子季铵盐抗菌整理剂的制备方法及应用 | |
CN106008810B (zh) | 一种抗菌剂及其制备方法 | |
CN107446153A (zh) | 一种季铵盐化聚乙烯醇‑纤维素‑氧化石墨烯复合膜的制备方法 | |
CN102153674B (zh) | 对氨基苯甲酸壳聚糖酯及其制备方法 | |
CN107827891A (zh) | 一系列与革兰氏阴性菌细菌膜特异性结合的光动力杀菌剂及制备方法 | |
CN102875814A (zh) | 聚硅氧烷及制备方法、用途以及含有该聚硅氧烷的杀菌剂 | |
CN101945605A (zh) | 抗微生物纤维素海绵及制备方法 | |
CN106967184A (zh) | 一种壳寡糖‑o‑香叶醇衍生物及其制备方法和用途 | |
CN103554367B (zh) | 一种含β-环糊精的卤胺类抗菌剂共聚物及其制备方法和应用 | |
CN110074105A (zh) | 一种新型高效复合胍基造纸杀菌剂 | |
CN107099031B (zh) | 一种耐高温改性聚六亚甲基胍及其制备方法和用途 | |
CN107129582B (zh) | 一种树形化杀菌微球及其制备方法和应用 | |
CN113197220B (zh) | 一种用于无纺布的除螨消毒剂及其制备方法 | |
CN115304528A (zh) | 一种可降解的双子季铵盐及其制备方法、杀菌剂 | |
CN107397961A (zh) | 一种提高聚乙烯亚胺抗大肠杆菌性能的方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20240202 Address after: 101200 room 205-211526, No. 40, Fuqian West Street, Pinggu town, Pinggu District, Beijing (cluster registration) Patentee after: BEIJING YONGBO TECHNOLOGY CO.,LTD. Country or region after: China Address before: No. 1800 road 214122 Jiangsu Lihu Binhu District City of Wuxi Province Patentee before: Jiangnan University Country or region before: China |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20240221 Address after: 310000 China (Zhejiang) Pilot Free Trade Zone, Hangzhou City, Zhejiang Province Room 3162, Floor 3, International Innovation Expo Center, No. 267, Science Park Road, Baiyang Street, Qiantang District, Hangzhou City Patentee after: Yiju (Hangzhou) Health Technology Co.,Ltd. Country or region after: China Address before: 101200 room 205-211526, No. 40, Fuqian West Street, Pinggu town, Pinggu District, Beijing (cluster registration) Patentee before: BEIJING YONGBO TECHNOLOGY CO.,LTD. Country or region before: China |
|
TR01 | Transfer of patent right |