CN105596667A - Joint pain relieving powder - Google Patents

Abstract

The invention discloses joint pain relieving powder. The joint pain relieving powder is prepared from notopterygium roots, radix stephaniae tetrandrae, cassia twig, golden cypress, rhizoma atractylodis, arisaema cum bile, rhizoma smilacis glabrae, Ligusticum wallichii, radix angelicae, peach kernels, radix clematidis, safflower carthamus, roots of aralis, ottelia alismoides, ainsliaea pertyoides, procumbent urena, ipomoea cairica, pterocephalus hookeri heck, cichory, L.leontopodiodes, sawgrass, spinach beet, autumn quince, valerian, lindernia ruellioides, garcinia multiflora and rubus parvifolius. The joint pain relieving powder has the advantages of treating four-limb joint pain, being good in effect, capable of taking effect rapidly and capable of well treating four-limb joint pain, errantly-wandering pain, flexion-extension difficulty, muscular rheumatism caused by arthritis, myotenositis, scapulohumeral periarthritis and myositis ossificans, wind-dampness-heat arthralgia and other diseases, having the good treatment effect, and being free of toxic or side effects and free of complications.

Description

A kind of joint medicinal powder for relieving pain

Technical field

The present invention relates to tcm field, relate to one and treat extremities joint pain, migration is indefinite, joint stuffiness, muscular rheumatism stagnation of cold-damp card, the medicine of the illnesss such as rheumatic fever numbness, particularly a kind of joint medicinal powder for relieving pain.

Background technology

Arthralgia is mainly to cause due to arthritis or arthropathy. It is very extensive and of a great variety that arthralgia involves scope, and therefore the antidiastole of arthralgia is most important. Arthralgia belongs to the illness categories such as the arthrodynia of extremeties, oncotic arthralgia of limbs, bi Zheng, gout in disease of tcm. Another arthralgia is shown in " Ling Shu Miraculous Pivot or Divine Axis all kinds of diseases and ailments begin raw ": " spinal column is strong for the obstructed four limbs of the six channels, the arthrodynia of extremeties. "

Position: one, goinyalgia; Two, marrow pain; Three, shoulder pain; Four, elbow pain; Five, wrist and hand pain.

Due to arthralgia position and pain cause difference, therefore need Coryza Treated by Syndrome Differentiation. Extremities joint pain, is shown in " Ling Shu Miraculous Pivot or Divine Axis all kinds of diseases and ailments begin raw ": " spinal column is strong for the obstructed four limbs of the six channels, the arthrodynia of extremeties. " because rheumatism, phlegm and retained fluid, hemostasis flow stagnant channels and collaterals, or the deficiency of blood can not nourishing the muscle and tendon due to.

Muscular rheumatism is weakened body resistance because of human body, and the damp and hot heresy of chill visitor is in muscle arteries and veins, or outer injuring tendons, or phlegm-damp oozing in the body muscle arteries and veins, qi and blood impatency, cause clinical taking muscular contracture contraction, take out the pain of pulling, joint flexing is unfavorable, back is tetanic, walk with difficulty etc. is a kind of disease of main manifestations. This disease is many in morbidity in spring, and age of onset is in the majority with person in middle and old age. Stagnation of cold-damp card syndrome: suffering limb is taken out the pain of pulling, and acid is swollen heavy, praises difficulty, meets overcast and rainy aggravation, must warm up and relax, and tongue is light, and tongue is greasy in vain, deep thready pulse or string. Pull bitterly with suffering limb, it is heavy tired that acid is swollen, and praising difficulty is assertive evidence diagnostic point.

For above-mentioned symptom, western medicine toxic and side effect is larger, and therefore Chinese traditional treatment has larger benefit.

Summary of the invention

In order to address the above problem, the invention provides a kind of joint medicinal powder for relieving pain.

In order to realize foregoing invention object, the invention provides a kind of joint medicinal powder for relieving pain, wherein, made by following raw medicinal material: notopterygium root, the root of fangji, cassia twig, golden cypress, rhizoma atractylodis, arisaema cum bile, smilax, Ligusticum wallichii, the root of Dahurain angelica, peach kernel, the root of Chinese clematis, safflower, Aralia wood root, waterplantain ottelia herb, whitetomentose ainsliaes herb, smallpox of ancient India, Ipomoea cairica, hooker winghead root, witloof, common edelweiss herb, alpine yarrow, Radix Betae, common floweringquince fruit, valerian, dry land grass, wooden bamboo and Rubus parvifolius.

Wherein, raw medicinal material by following mass fraction makes: notopterygium root 10-20 weight portion, root of fangji 10-20 weight portion, cassia twig 10-20 weight portion, golden cypress 10-20 weight portion, rhizoma atractylodis 10-20 weight portion, arisaema cum bile 10-20 weight portion, smilax 10-20 weight portion, Ligusticum wallichii 10-20 weight portion, root of Dahurain angelica 10-20 weight portion, peach kernel 10-20 weight portion, root of Chinese clematis 10-20 weight portion, safflower 10-20 weight portion, Aralia wood root 3-5 weight portion, waterplantain ottelia herb 10-15 weight portion, whitetomentose ainsliaes herb 2-6 weight portion, smallpox 10-15 weight portion of ancient India, Ipomoea cairica 8-10 weight portion, hooker winghead root 10-15 weight portion, witloof 8-15 weight portion, common edelweiss herb 10-15 weight portion, alpine yarrow 6-12 weight portion, Radix Betae 6-10 weight portion, common floweringquince fruit 6-9 weight portion, valerian 10-15 weight portion, dry land grass 8-13 weight portion, wood bamboo 8-12 weight portion and Rubus parvifolius 10-15 weight portion.

Wherein, raw medicinal material by following mass fraction makes: notopterygium root 18 weight portions, the root of fangji 15 weight portions, cassia twig 15 weight portions, golden cypress 13 weight portions, rhizoma atractylodis 16 weight portions, arisaema cum bile 18 weight portions, smilax 16 weight portions, Ligusticum wallichii 17 weight portions, the root of Dahurain angelica 16 weight portions, peach kernel 13 weight portions, the root of Chinese clematis 12 weight portions, safflower 15 weight portions, Aralia wood root 4 weight portions, waterplantain ottelia herb 12 weight portions, whitetomentose ainsliaes herb 4 weight portions, smallpox 13 weight portions of ancient India, Ipomoea cairica 9 weight portions, hooker winghead root 12 weight portions, witloof 12 weight portions, common edelweiss herb 12 weight portions, alpine yarrow 8 weight portions, Radix Betae 9 weight portions, common floweringquince fruit 8 weight portions, valerian 12 weight portions, dry land grass 10 weight portions, wood bamboo 10 weight portions and Rubus parvifolius 13 weight portions.

The invention has the beneficial effects as follows: medicine of the present invention, treatment extremities joint pain, effective, instant effect, can be good at treating extremities joint pain, migration is indefinite, joint stuffiness, muscular rheumatism stagnation of cold-damp card, the illnesss such as rheumatic fever numbness, there is good result for the treatment of, and have no side effect, without complication.

Detailed description of the invention

The invention provides a kind of joint medicinal powder for relieving pain, wherein, comprise following raw medicinal material: notopterygium root, the root of fangji, cassia twig, golden cypress, rhizoma atractylodis, arisaema cum bile, smilax, Ligusticum wallichii, the root of Dahurain angelica, peach kernel, the root of Chinese clematis, safflower, Aralia wood root, waterplantain ottelia herb, whitetomentose ainsliaes herb, smallpox of ancient India, Ipomoea cairica, hooker winghead root, witloof, common edelweiss herb, alpine yarrow, Radix Betae, common floweringquince fruit, valerian, dry land grass, wooden bamboo and Rubus parvifolius. Ingredients scientific matching, reaches the arthralgic object for the treatment of, has good effect.

The pharmacology of various raw medicinal materials is as follows:

Notopterygium root: [another name] silkworm Qiang, RHIZOMA SEU RADIX NOTOPTERYGII, RHIZOMA SEU RADIX NOTOPTERYGII, dog introduction flower, Koji. [nature and flavor] are pungent, bitter, temperature. [return through] returns bladder, kidney channel. [function cures mainly] is loose cold, dispel the wind, and dehumidifying, pain relieving. For anemofrigid cold headache, arthralgia due to wind-dampness, aching pain in should and back.

The root of fangji: [another name] Fourstamen Stephania Root, powder cun oneself, Stephania tetrandra, RADIX COCULI [Zhejiang], stone toad, toad potato, the arch that falls down to the ground, suspension culture of Aquilaria sinensis, Radix Polygalae Crotalarioidis. [nature and flavor] hardship, cold. [return through] returns bladder, lung channel. [function cures mainly] inducing diuresis for removing edema, wind-expelling pain-stopping. For oedema beriberi, difficult urination, eczema sore, arthralgia due to wind-dampness; Hypertension.

Cassia twig: [nature and flavor] acrid, sweet, warm. [return through] thoughts of returning home, lung, urinary bladder channel. [function cures mainly] sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, the flat gas that spins. For anemofrigid cold, coldness and pain in the epigastrium, blood is cold through closing, joint pain, and phlegm and retained fluid, oedema, palpitaition, globefish runs quickly.

Golden cypress: [nature and flavor] hardship, cold. [return through] returns kidney, urinary bladder channel. [function cures mainly] heat-clearing and damp-drying drug, purging intense heat is except steaming, detoxification sore treatment. For damp-heat dysentery, jaundice, under band, heat is drenched, beriberi, and impotence { is warded off }, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema itch. Stir-baked CORTEX PHELLODENDRI with salt solution is nourishing Yin and falling fire. For fire excess from yin deficiency, night sweat hectic fever due to yin.

Rhizoma atractylodis: [another name] red art, rifle head dish. [nature and flavor] are pungent, bitter, temperature. [return through] returns spleen, stomach, Liver Channel. [function cures mainly] is drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight. For abdominal fullness and distention, have loose bowels, oedema, beriberi Wei lame, arthralgia due to wind-dampness, anemofrigid cold, yctalopia.

Arisaema cum bile: fine powder and ox, sheep or pig's bile that [source] this product is Rhizoma Arisaematis (processed) process from strand, or be that unprocessed Arisaema erubescens fine powder and ox, sheep or pig's bile process through fermentation. [nature and flavor] are bitter, micro-pungent, cool. [return through] returns lung, liver, the spleen channel. [function cures mainly] clearing heat and eliminating phlegm, dispelling wind and relieving convulsion. For phlegm-heat cough, cough up phlegm yellow thick, apoplexy phlegm fan, demented frightened epilepsy.

Smilax: [nature and flavor] are sweet, light is flat. [return through] returns liver, stomach warp. [function cures mainly] dehumidifying, removing toxic substances, easing joint movement. For damp and hot stranguria with turbid discharge, under band, carbuncle is swollen, scrofula, mange, the limbs contraction due to syphilis and mercury poisoning, arthralgia and myalgia.

Ligusticum wallichii: [nature and flavor] are pungent, temperature. [return through] returns liver, courage, pericardium channel. [function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping. For irregular menstruation, through closing dysmenorrhoea ， Disorder lump in the abdomen stomachache, the shouting pain of the chest side of body, tumbling and swelling, headache, arthralgia due to wind-dampness.

The root of Dahurain angelica: [nature and flavor] are pungent, temperature. [return through] returns stomach, large intestine, lung channel. [function cures mainly] loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis. For cold headache, pain in the supra-orbital bone, nasal obstruction, nasosinusitis, toothache, leukorrhea, sore swells and ache.

Peach kernel: [nature and flavor] bitter, sweet, flat. [return through] thoughts of returning home, liver, large intestine channel. [function cures mainly] promoting blood circulation, relaxes bowel. Be used for through closing dysmenorrhoea ， Disorder lump in the abdomen lump in the abdomen, injury from falling down, the dry constipation of intestines.

The root of Chinese clematis: [nature and flavor] are pungent, salty, temperature. [return through] returns urinary bladder channel. [function cures mainly] dispels rheumatism, and removes obstruction in channels to relieve pain. For arthralgia due to wind-dampness, extremity numbness, the contraction of muscle arteries and veins, joint stuffiness, the bone larynx of choking with sobs.

Safflower: [nature and flavor] are pungent, temperature. [return through] thoughts of returning home, Liver Channel. [function cures mainly] activating blood to promote menstruation, blood stasis removing analgesic. Be used for through closing, dysmenorrhoea, lochia ， Disorder lump in the abdomen lump in the abdomen, injury from falling down, sore swells and ache.

Aralia wood root: [source] adds root or the root skin of the Zhi Wu of section Aralia wood for Wu. Uproot 9～October, or strip root skin and dry. [nature and flavor] are pungent, flat. 1. supplement to the Herbal: " pungent, flat. " 2. " vegetation is side just ": " hardship, is slightly cold. " 3. " Kweiyang medicinal herbs among the people ": " are sweet, cold, nontoxic. " [function cures mainly] wines used as antirheumatic, diuresis, loose hemostasis, detumescence poison. Treating rheumatic arthritis, nephritic dropsy, cirrhotic ascites, acute, chronic hepatitis, stomachache, stranguria with turbid discharge, metrorrhagia, traumatic injury, scrofula, carbuncle is swollen.

Waterplantain ottelia herb: dish, water-white dish, water leaf mustard, water lettuce, dragon's paw grass, edible seaweed at the bottom of [another name] pool. [source] Hydrocharctaceae Ottelia plant dragon's tongue, with all herbal medicine. Spring and summer is adopted herb, cleans and dries. [nature and flavor] are sweet, light, cool. [function cures mainly] clearing heat and eliminating phlegm, removing toxic substances diuresis. For cough with lung heat, pulmonary tuberculosis, hemoptysis, asthma, oedema, difficult urination; It is swollen that carbuncle is controlled in external application, burn and scald.

Whitetomentose ainsliaes herb: [another name] wind catching arrow. [source] carries on the back Ainsliaea in vain for composite family Ainsliaea platymiscium, with all herbal medicine. The four seasons can adopt, using fresh herb or dry. [nature and flavor] hardship, temperature. [function cures mainly] damp dispelling and pain relieving, the promoting flow of qi and blood circulation. For rheumatic arthritis, traumatic injury, lymphnoditis; Fracture is controlled in external application, traumatism and bleeding.

Smallpox of ancient India: [source] is the herb of Malvaceae plant smallpox of ancient India. Summer, Qiu Cai, remove root, dries. [nature and flavor] are " Fujian traditional herbal medicine " 1.: " sweet, temperature. " 2. " the practical Chinese herbal medicine in Guangxi newly selects ": " is lightly seasoned micro-sweet, cool in nature. " [function cures mainly] removing toxic substances of dispeling the wind. Control dysentery, sore, wind poison streamer, venomous snake bite. 1. " Illustrated Book on Plants ": " control windage loss. " 2. " Fujian traditional herbal medicine ": " dispels rheumatism, eliminating inflammation and expelling toxin. Control wind poison streamer, mad dog is bitten. " 3. " the practical Chinese herbal medicine in Guangxi newly selects ": " anti-inflammation detumescence, removing pattogenic heat from the blood and toxic material from the body. Cure mainly dysentery, diarrhoea, furuncle, rabies, venomous snake bite. "

Ipomoea cairica: [another name] cairo morningglory root or leaf, little Ipomoea cairica. [nature and flavor] are bitter, puckery, temperature. [function cures mainly] dispelling, collateral-activating, promoting blood circulation and stopping pain. For treating rheumatic ostealgia, traumatic injury; Fracture is controlled in external application, traumatism and bleeding.

Hooker winghead root: [another name] ear of maize head, lion grass. The first flower plant root of Hooker Winghead of [source] Dipsacaceae wing, is used as medicine with whole herb with root. Between bud stage, take whole herb with root 7 the end of month, clean segment, dry. [nature and flavor] hardship, cold. Slightly poisonous. [function cures mainly] relieving superficies by cooling, cool blood clears away heart-fire. Be used for the fever that cold, fever and various warm heat disease cause, dysphoria with smothery sensation in the heart, hemoptysis, spits blood, and hematuria, has blood in stool.

Witloof: [nature and flavor] micro-hardship, salty, cool. [function cures mainly] clearing liver cholagogic, stomach strengthening and digestion promoting, inducing diuresis to reduce edema. For jaundice with damp-heat pathogen, stomachache food is few, oedema oliguria.

Common edelweiss herb: the fragrant Chinese mugwort of [another name] little lance (" Chinese herbal medicine handbook is commonly used in Qinghai "), old man's end (" Chinese herbal medicine handbook is commonly used in Heilungkiang "). [nature and flavor] " Chinese herbal medicine handbook is commonly used in northeast ": " micro-hardship, cold. " [function cures mainly] be " Chinese herbal medicine handbook is commonly used in northeast " 1.: " clearing heat and cooling blood, kidney-nourishing Li Shui. Control acute nephritis, hematuria. " 2. " the conventional Chinese herbal medicine handbook in the north ": " clearing heat and cooling blood, anti-inflammatory diuresis. Control urgency, chronic nephritis is effective to disappearance albuminuria and blood urine. "

Alpine yarrow: [another name] lotus in May, ciliate falsepimpernel herb. [source] Scrophulariaceae Vandellia plant tingia Brittle Falsepimpernel Herb, with all herbal medicine. Xia Qiu gathers, many using fresh herbs. [nature and flavor] are light, flat. [function cures mainly] is clearing heat and detoxicating, eliminating stasis to resolve swelling, pain relieving. For venomous snake bite, traumatic injury, postpartum blood stasis stomachache; Sore furuncle pain is controlled in external application.

Radix Betae: [source] plants stem, the leaf of plant Radix Betae for multitude. [nature and flavor] are sweet, cool. 1. not " not Lu ": " sweetness and bitterness, Great Cold. " 2. " Japan hanako materia medica ": " is cold, nontoxic. " 3. " the good book on Chinese herbal medicine of helping ": " is flat, micro-poison. " 4. herbal for Relief of Famines: " taste is salty, and property is flat cold, micro-poison. " [return through] 1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enters Yangming Channel. " 2. " book on Chinese herbal medicine brief points ": " meridian of Foot-TAI YIN of starting with. " [function cures mainly] is clearing heat and detoxicating, the hemostasis of the row stasis of blood. Control measles and thoroughly send out unhappy, hot malicious diarrhea, amenorrhoea stranguria with turbid discharge, carbuncle is swollen traumatics fracture.

Common floweringquince fruit: [nature and flavor] are bitter, temperature. 1. " Yunnan Pu's book on Chinese herbal medicine ": " toil is sweet, tepor. " 2. " Illustrated Book on Plants ": " is sour and astringent. " 3. " Chengdu Chinese herbal medicine ": " is sour and astringent, and temperature is nontoxic. " [function cures mainly] easypro liver and stomach, damp dispelling and pain relieving. Control the discomfort uncomfortable in chest of vomiting and diarrhoea, rheumatism arthralgia and myalgia, beriberi. 1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control arthralgia and myalgia, convulsive seizure due to phlegm-fire pin is soft. " 2. " Chinese medicine shape sex experience differential method ": " relaxing muscles and tendons, pain relieving, only urine. Treatment of rheumatalgia pain, joint, four limbs spasm. " 3. " Chengdu Chinese herbal medicine ": " easypro liver and stomach, damp dispelling and pain relieving. "

Valerian: [another name] valerian, little rescuing [Shaanxi], deer grass, stinkweed [source] Valerianaceae valerian valerian and Valeriana amurensis Smir. ex Kom, be used as medicine with root-like stock and root. Gather autumn, removes rice shoot and earth, dries. [nature and flavor] acrid, sweet, warm. [function cures mainly] calms the nerves, regulate the flow of vital energy, and pain relieving. For neurasthenia, insomnia, hysteria, epilepsy, stomach abdominal distention and pain, pain in waist and lower extremities, traumatic injury.

Dry land grass: [another name] longcapsuled falsepimpernel herb, small size brave tongue Huang, brave tongue ciliate desert-grass, field jasmine, Herba Linderniae ruellioidis, evergreen euonymus root, double end town, snake melon perfume (or spice), underground tea, earrings grass, tortoise medicine, saw sickle grass [source] Scrophulariaceae Vandellia plant dry land grass, with all herbal medicine. Xia Qiu gathers, and cleans using fresh herb or dry. [nature and flavor] are sweet, light, flat. [function cures mainly] vital energy regualting and blood circulation-promoting, swelling and pain relieving. For amenorrhoea, dysmenorrhoea, stomachache, mastitis, lymphoid tuberculosis; Traumatic injury is controlled in external application, the carbuncle pain that swells, snake bite, lyssodexis.

Wood bamboo: [source] is fruit, fruit stone, the bark of Garcinia maingayii south of the Five Ridges garcinia mangostana. When Fruit In Winter maturation turns yellow, pluck, bark can be adopted the whole year. [nature and flavor] 1. " Gui Haiyu weigh will ": " sweet. " 2. Yao can become " food book on Chinese herbal medicine ": " taste is sweet, flat. " [function cures mainly] 1. Yao can become " food book on Chinese herbal medicine ": " main heat-clearing, sharp hundred arteries and veins, logical water transfer is dirty, slakes thirst and help produce saliva, relieving summer-heat, wine disappears. Control and tell against not eating, obstruction and rejection is closed and is refused to lead to, insufficiency of the spleen sinking, and anus pendant is de-not to be held back. Heat-clearing, cool large intestine, removes hematocele, and sharp knowledge, controls cough with dyspnea. "

Rubus parvifolius: [bubble, red plum disappeared, Herba Rubi parvifolii, ulled up seedling Fischer [source] rose family rubus Rubus parvifolius another name] She Pao le, March, were used as medicine with root or stem, leaf. Uproot autumn, Xia Qiucai cauline leaf, and using fresh herb or segment are dried. [nature and flavor] are bitter, puckery, cool. [function cures mainly] clearing heat and cooling blood, dissipating bind, pain relieving, inducing diuresis to reduce edema. For cold, fever, abscess of throat, spitting of blood, spits blood, dysentery, enteritis, hepatitis, hepatosplenomegaly, nephritic dropsy, urinary infection, calculus, irregular menstruation, leukorrhea, treating rheumatic ostealgia, treating swelling and pain by traumatic injury; Eczema is controlled in external application, dermatitis.

The present invention is preferably only made by above raw medicinal material.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.

Embodiment 1

Proportioning: notopterygium root 10 weight portions, the root of fangji 10 weight portions, cassia twig 10 weight portions, golden cypress 10 weight portions, rhizoma atractylodis 10 weight portions, arisaema cum bile 10 weight portions, smilax 10 weight portions, Ligusticum wallichii 10 weight portions, the root of Dahurain angelica 10 weight portions, peach kernel 10 weight portions, the root of Chinese clematis 10 weight portions, safflower 10 weight portions, Aralia wood root 3 weight portions, waterplantain ottelia herb 10 weight portions, whitetomentose ainsliaes herb 2 weight portions, smallpox 10 weight portions of ancient India, Ipomoea cairica 8 weight portions, hooker winghead root 10 weight portions, witloof 8 weight portions, common edelweiss herb 10 weight portions, alpine yarrow 6 weight portions, Radix Betae 6 weight portions, common floweringquince fruit 6 weight portions, valerian 10 weight portions, dry land grass 8 weight portions, wood bamboo 8 weight portions and Rubus parvifolius 10 weight portions.

Its preparation method is:

Step 1: by safflower, peach kernel grind into powder; Step 2: get again surplus stock medicinal material and add 80% alcohol immersion 1 hour of 4 times of amounts, heating to extract 2 times, each 1.0 hours, filter to obtain extract, merge extract, be 54000 ultrafiltration post ultrafiltration again through the molecular weight that dams, ethanol is removed in ultrafiltration decompression, the medicinal extract that when 90 DEG C of simmer down tos, relative density is 1.03, becomes component 1; Step 3: the dregs of a decoction that step 2 obtains add 3 times of water gagings and soak 2.0 hours, extracts 1 time for 1.5 hours, and the medicinal extract that during by 85 DEG C of extract decompression heating simmer down tos, relative density is 1.1, as component 2; Step 4: the powder that component 1, component 2 are obtained with step 1 mixes, adds with respect to the honey of 2 times of amounts of mixture and is twisted into honey refining pill.

Embodiment 2

Proportioning: notopterygium root 20 weight portions, the root of fangji 20 weight portions, cassia twig 20 weight portions, golden cypress 20 weight portions, rhizoma atractylodis 20 weight portions, arisaema cum bile 20 weight portions, smilax 20 weight portions, Ligusticum wallichii 20 weight portions, the root of Dahurain angelica 20 weight portions, peach kernel 20 weight portions, the root of Chinese clematis 20 weight portions, safflower 20 weight portions, Aralia wood root 5 weight portions, waterplantain ottelia herb 15 weight portions, whitetomentose ainsliaes herb 6 weight portions, smallpox 15 weight portions of ancient India, Ipomoea cairica 10 weight portions, hooker winghead root 15 weight portions, witloof 15 weight portions, common edelweiss herb 15 weight portions, alpine yarrow 12 weight portions, Radix Betae 10 weight portions, common floweringquince fruit 9 weight portions, valerian 15 weight portions, dry land grass 13 weight portions, wood bamboo 12 weight portions and Rubus parvifolius 15 weight portions.

Its preparation method is:

The first step, mixes described raw medicinal material in proportion, is ground into powder;

Second step, obtains powder by the first step and adds in cold water and soak 8 hours, and with slow fire boiling, decocting time is 3 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water adding is 3 times of the powder quality that obtains of the first step;

The 3rd step, filters by second step the filter residue obtaining and again adds in cold water, with slow fire boiling 3 hours, filters and obtains the second filtrate, and the quality of the water adding is 3 times of powder quality that second step obtains;

The 4th step, the second filtrate that the first filtrate that second step is obtained and the 3rd step obtain is mixed, and reduced pressure concentration, except anhydrating, dry, pulverize powdered, and granularity is 90 orders;

The 5th step, in the powder obtaining, adds starch in described the 4th step, and the percentage by weight of described starch in described powder is 20%, mixes and obtains powder.

Embodiment 3

Proportioning: notopterygium root 18 weight portions, the root of fangji 15 weight portions, cassia twig 15 weight portions, golden cypress 13 weight portions, rhizoma atractylodis 16 weight portions, arisaema cum bile 18 weight portions, smilax 16 weight portions, Ligusticum wallichii 17 weight portions, the root of Dahurain angelica 16 weight portions, peach kernel 13 weight portions, the root of Chinese clematis 12 weight portions, safflower 15 weight portions, Aralia wood root 4 weight portions, waterplantain ottelia herb 12 weight portions, whitetomentose ainsliaes herb 4 weight portions, smallpox 13 weight portions of ancient India, Ipomoea cairica 9 weight portions, hooker winghead root 12 weight portions, witloof 12 weight portions, common edelweiss herb 12 weight portions, alpine yarrow 8 weight portions, Radix Betae 9 weight portions, common floweringquince fruit 8 weight portions, valerian 12 weight portions, dry land grass 10 weight portions, wood bamboo 10 weight portions and Rubus parvifolius 13 weight portions.

Its preparation method is:

The first step, mixes described each raw medicinal material in proportion, and the ethanol that to add with respect to the determining alcohol of 3 times of mixture qualities be 90%, adds hot reflux 2 hours, extracts, and filters and obtains the first extract; The ethanol that it is 90% that the dregs of a decoction that filtration obtains add with respect to the determining alcohol of 2 times of described dregs of a decoction quality again, adds hot reflux 2 hours, extracts, and filters and obtains the second extract; The first extract and the second extract are merged, and reduced pressure concentration is removed alcohol solvent, dry, obtains and gets dry extract; Second step, the dry cream that the first step is obtained is placed in micronizer to be pulverized 2 hours, pulverizes, and sieves, and obtains 350 object micropowders; The 3rd step adds the starch with respect to 2 times of its quality in the micropowders that second step is obtained, and mixes, and obtains powder.

The toxicity test of medicine

1. acute toxicity test: 40 of application NIH mouse, SPF level, male and female half and half, body weight 18～22g, carries out acute toxicity test. Mouse is divided into two groups at random, and 20 every group, i.e. control group and administration group, fasting 12 hours before experiment; Honey refining pill prepared by embodiments of the invention 1 is dissolved in water, (concentration is 8g crude drug/ml, maximum concentration) gavage, gavage volume is that 5ml/kg(is that single-dose dosage is 40 crude drugs/kg), control group gives equivalent physiological saline, administration in a day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mouse toxic reaction and death toll. Experimental result shows: with control group comparison, after administration, mouse has no notable difference, experiment Continuous Observation 14 days, and mouse overall health of patients, diet, drinking-water, body weight gain are all normal. Mouse oral administration gavage medicine LD50 of the present invention > 40 crude drugs/kg, every day, maximum dosage-feeding was 80 crude drugs/kg/ day. Chinese medicine clinical application amount of the present invention is 10g crude drug/day/people, becomes body weight for humans in 60KG, and average dosage is 0.166g crude drug/kg/ day. By batheroom scale: the dosis tolerata of mouse (average weight is taking 20g) oral administration gavage Chinese medicine of the present invention is 481 times of quantity. Therefore Acute toxicity of the present invention is low, clinical drug safety.

2. long term toxicity test: by the powder of the embodiment of the present invention 3 to mouse by 8,16 and 12 weeks (1.0ml/100g body weight of 40g crude drug/kg continuous use, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as the hair of medicine of the present invention to mouse, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, blood fat all has no significant effect, internal organs naked eyes do not find that difference changes and histological examination result shows, medication 12 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing. Illustrate that toxicity is little after medicine of the present invention is to mouse long-term prescription, after drug withdrawal, also there is no difference reaction, application safety.

Clinical testing

Case selection: during selecting in May, 2014-2015 year January, the patient of certain hospital therapy is totally 200 examples. Suffer from extremities joint pain, migration is indefinite, joint stuffiness, muscular rheumatism stagnation of cold-damp card, the illnesss such as rheumatic fever numbness. Wherein, male 102 examples, female's 98 examples, 75 examples in 45 years old-50 years old age, 65 examples of 50 years old-60 years old, over-65s60Example. Be divided at random four groups, every group of 50 people, 1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment and control group. Four groups of patients comparing difference not statistically significant aspect age, sex, state of an illness weight, has comparativity, and according to the weight treat-and-release of the state of an illness.

Methods for the treatment of:

1 group of embodiment: this group is used the honey refining pill of embodiments of the invention 1 to treat. Each oral 1 ball, 3 times on the one 7 days is a course for the treatment of, treats 2 courses for the treatment of.

2 groups of embodiment: this group is used the powder of embodiments of the invention 2 to treat. Each warm water 5g that takes after mixing it with water, 3 times on the one 7 days is a course for the treatment of, treats 2 courses for the treatment of.

3 groups of embodiment: this group is used the powder of embodiments of the invention 3 to treat. Each warm water 5g that takes after mixing it with water, 3 times on the one 7 days is a course for the treatment of, treats 2 courses for the treatment of.

Control group: this group is used C14H10Cl2NNaO2 sheet to treat. 75mg-150mg on the one, point 3 clothes, 7 days are a course for the treatment of, treat 2 courses for the treatment of.

Efficacy evaluation

Clinical cure: symptom and sign disappears completely; Effective: symptom disappears substantially; Take a turn for the better: symptom is improved; Invalid: symptom and sign is without improvement.

Treatment results

Table 1 is the treatment situation contrast of each group

Group	Clinical cure	Effective	Take a turn for the better	Do not heal
					1 group of embodiment	49（98%）	1（2%）	0（0%）	0（0%）
2 groups of embodiment	49（98%）	1（2%）	0（0%）	0（0%）
					3 groups of embodiment	50（100%）	0（0%）	0（0%）	0（0%）
Control group	18（36%）	2（4%）	10（20%）	20（40%）

As can be seen from Table 1, the treatment situation of three embodiment groups is better than the result for the treatment of of control group, and hence one can see that, medicine of the present invention, at treatment extremities joint pain, migration is indefinite, joint stuffiness, muscular rheumatism stagnation of cold-damp card, the illnesss such as rheumatic fever numbness, result for the treatment of is good, determined curative effect.

Table 2 is recurrence and the side effect contrast (toxic and side effect rate=side effect number/total number of persons, recurrence rate=recurrence number/clinical cure number) of each group

Group	Toxic and side effect incidence	Recurrence rate
			1 group of embodiment	0（0%）	0（0%）
2 groups of embodiment	0（0%）	0（0%）
			3 groups of embodiment	0（0%）	0（0%）
Control group	3（6%）	1（5.6%）

As can be seen from Table 2, the toxic and side effect of three embodiment groups and recurrence number result are all better than control group. Hence one can see that, medicine treatment extremities joint pain of the present invention, and migration is indefinite, and joint stuffiness is demonstrate,proved by muscular rheumatism stagnation of cold-damp, and the illnesss such as rheumatic fever numbness, do not have toxic and side effect, do not recur.

Model case: institute of traditional Chinese medicine of Shandong Province accepts the patient of diagnosis and treatment, 55 years old, suffers from muscular rheumatism stagnation of cold-damp card 1 year half. Use the powder of embodiments of the invention 3 to treat. Each warm water 5g that takes after mixing it with water, 3 times on the one 7 days is a course for the treatment of, treats 2 courses for the treatment of. In therapeutic process, do not occur other bad reactions, 2 courses for the treatment of, clinical cure are carried out in treatment. Later stage does not recur.

The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (3)

1. a joint medicinal powder for relieving pain, it is characterized in that, made by following raw medicinal material: notopterygium root, the root of fangji, cassia twig, golden cypress, rhizoma atractylodis, arisaema cum bile, smilax, Ligusticum wallichii, the root of Dahurain angelica, peach kernel, the root of Chinese clematis, safflower, Aralia wood root, waterplantain ottelia herb, whitetomentose ainsliaes herb, smallpox of ancient India, Ipomoea cairica, hooker winghead root, witloof, common edelweiss herb, alpine yarrow, Radix Betae, common floweringquince fruit, valerian, dry land grass, wooden bamboo and Rubus parvifolius.

2. joint according to claim 1 medicinal powder for relieving pain, it is characterized in that, raw medicinal material by following mass fraction makes: notopterygium root 10-20 weight portion, root of fangji 10-20 weight portion, cassia twig 10-20 weight portion, golden cypress 10-20 weight portion, rhizoma atractylodis 10-20 weight portion, arisaema cum bile 10-20 weight portion, smilax 10-20 weight portion, Ligusticum wallichii 10-20 weight portion, root of Dahurain angelica 10-20 weight portion, peach kernel 10-20 weight portion, root of Chinese clematis 10-20 weight portion, safflower 10-20 weight portion, Aralia wood root 3-5 weight portion, waterplantain ottelia herb 10-15 weight portion, whitetomentose ainsliaes herb 2-6 weight portion, smallpox 10-15 weight portion of ancient India, Ipomoea cairica 8-10 weight portion, hooker winghead root 10-15 weight portion, witloof 8-15 weight portion, common edelweiss herb 10-15 weight portion, alpine yarrow 6-12 weight portion, Radix Betae 6-10 weight portion, common floweringquince fruit 6-9 weight portion, valerian 10-15 weight portion, dry land grass 8-13 weight portion, wood bamboo 8-12 weight portion and Rubus parvifolius 10-15 weight portion.

3. joint according to claim 1 and 2 medicinal powder for relieving pain, it is characterized in that, raw medicinal material by following mass fraction makes: notopterygium root 18 weight portions, the root of fangji 15 weight portions, cassia twig 15 weight portions, golden cypress 13 weight portions, rhizoma atractylodis 16 weight portions, arisaema cum bile 18 weight portions, smilax 16 weight portions, Ligusticum wallichii 17 weight portions, the root of Dahurain angelica 16 weight portions, peach kernel 13 weight portions, the root of Chinese clematis 12 weight portions, safflower 15 weight portions, Aralia wood root 4 weight portions, waterplantain ottelia herb 12 weight portions, whitetomentose ainsliaes herb 4 weight portions, smallpox 13 weight portions of ancient India, Ipomoea cairica 9 weight portions, hooker winghead root 12 weight portions, witloof 12 weight portions, common edelweiss herb 12 weight portions, alpine yarrow 8 weight portions, Radix Betae 9 weight portions, common floweringquince fruit 8 weight portions, valerian 12 weight portions, dry land grass 10 weight portions, wood bamboo 10 weight portions and Rubus parvifolius 13 weight portions.