CN105596434A - Licorice electuary for clearing heat and detoxifying as well as preparation method thereof - Google Patents

Licorice electuary for clearing heat and detoxifying as well as preparation method thereof Download PDF

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CN105596434A
CN105596434A CN201410681268.6A CN201410681268A CN105596434A CN 105596434 A CN105596434 A CN 105596434A CN 201410681268 A CN201410681268 A CN 201410681268A CN 105596434 A CN105596434 A CN 105596434A
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parts
radix glycyrrhizae
radix
roots
eucommia
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马玉国
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Harbin Shengji Pharmaceutical Co Ltd
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Harbin Shengji Pharmaceutical Co Ltd
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Abstract

The invention provides a licorice electuary for clearing heat and detoxifying and a preparation method thereof. The electuary is prepared by the following components: licorice, codonopsis roots, bupleurum roots, Szechuan lovage rhizome, cornus fruits, eucommia barks, corydalis tubers, cinnamon, notopterygium roots, pueraria roots, tamarisk twigs and leaves, fermented soybeans, xylo oligosaccharide, rock sugar and microcrystalline cellulose. A preparation method comprises the following steps: pretreatment of raw materials, preparation of a mixed extract, condensation, drying, crushing, mixing, pelletization, drying, arrangement of granules, and package in bags. The licorice electuary for clearing heat and detoxifying has the effects for clearing heat, detoxifying, moistening lung, relieving cough, moderating the property of herbs to different degrees for swollen sore throat, cough and other main diseases, and has the advantages of health care, fast effectiveness, pure natural materials without toxicity and side-effects, etc.

Description

A kind of Radix Glycyrrhizae Qingrejiedu Granules and preparation method thereof
Technical field
The present invention relates to health product technology field, particularly a kind of Radix Glycyrrhizae Qingrejiedu Granules and preparation method thereof.
Background technology
Carbuncle furuncle poison: furuncle is the swollen thing of relatively large redness forming after hair follicle is infected by bacterium. furuncle mostly occurs at the position of human body pressurized, as neck eckband place or buttocks. furuncle often has violent pulsation to jump pain in the process forming, if especially furuncle length is in the densification of the skin histology such as forehead or lower jaw, the position that tension force is higher, can pain obtain more severe. general mistake after a couple of days, the central authorities of red swollen thing can form purulence and fasten, meeting ulceration voluntarily after two or three days. may not there is not ulceration and die away in the furuncle also having. and though furuncle is not very serious disease, but because closely adjacent between hair follicle, if process not in time the furuncle having grown, not only hurt like hell, and easily cause the infection of surrounding skin, can grow more furuncle.
At present, medicine or health products clearing heat and detoxicating on market have a lot, but the effect of most drug is not fine, and the side effect of most drug is more, can damage health, though health products have certain effect, but its price is high, therefore Radix Glycyrrhizae Qingrejiedu Granules that, be badly in need of a kind of pure natural on market, has no side effect and preparation method thereof.
Summary of the invention
The object of this invention is to provide a kind of clearing heat and detoxicating, moisten the lung and relieve the cough, Radix Glycyrrhizae Qingrejiedu Granules of coordinating the drug actions of a prescription and preparation method thereof.
Object of the present invention is achieved through the following technical solutions: a kind of Radix Glycyrrhizae Qingrejiedu Granules, be prepared from Radix Glycyrrhizae 50-60 part, Radix Codonopsis 20-30 part, radix bupleuri 20-30 part, Ligusticum wallichii 20-30 part, Fructus Corni 15-20 part, bark of eucommia 15-20 part, corydalis tuber 15-20 part, Chinese cassia tree 10-15 part, notopterygium root 10-15 part, root of kudzu vine 10-15 part, Chinese tamarisk tops 10-15 part, Fermented Soybean 10-15 part, xylo-oligosaccharide 10-15 part, rock sugar 5-10 part, microcrystalline cellulose 5-10 part by following parts by weight.
Preferred version 1:
A kind of Radix Glycyrrhizae Qingrejiedu Granules, be prepared from 60 parts, Radix Glycyrrhizae, 30 parts of Radix Codonopsis, 30 parts of radix bupleuri, 30 parts of Ligusticum wallichiis, 17 parts of Fructus Cornis, 17 parts of the barks of eucommia, 17 parts of corydalis tubers, 15 parts of Chinese cassia trees, 15 parts of notopterygium roots, 15 parts of the roots of kudzu vine, 15 parts of Chinese tamarisk tops, 15 parts of Fermented Soybeans, 10 parts of xylo-oligosaccharides, 10 parts, rock sugar, 10 parts of microcrystalline celluloses by following parts by weight.
Preferred version 2:
A kind of Radix Glycyrrhizae Qingrejiedu Granules, be prepared from 55 parts, Radix Glycyrrhizae, 25 parts of Radix Codonopsis, 25 parts of radix bupleuri, 25 parts of Ligusticum wallichiis, 15 parts of Fructus Cornis, 15 parts of the barks of eucommia, 15 parts of corydalis tubers, 13 parts of Chinese cassia trees, 13 parts of notopterygium roots, 13 parts of the roots of kudzu vine, 13 parts of Chinese tamarisk tops, 13 parts of Fermented Soybeans, 12 parts of xylo-oligosaccharides, 8 parts, rock sugar, 8 parts of microcrystalline celluloses by following parts by weight.
Described a kind of Radix Glycyrrhizae Qingrejiedu Granules and preparation method thereof, the key step of its preparation method is:
Step 1: pretreatment of raw material: by weight, choose Radix Glycyrrhizae, Radix Codonopsis, radix bupleuri, Ligusticum wallichii, Fructus Corni, the bark of eucommia, corydalis tuber, Chinese cassia tree, notopterygium root, the root of kudzu vine, Chinese tamarisk tops, Fermented Soybean, clean and removal of impurities, for subsequent use;
Step 2: prepare mixed extract: Radix Glycyrrhizae, Radix Codonopsis, radix bupleuri, Ligusticum wallichii, Fructus Corni, the bark of eucommia, corydalis tuber, Chinese cassia tree, notopterygium root, the root of kudzu vine, Chinese tamarisk tops, Fermented Soybean are mixed, and then water decocts three times, the little fire that adds water for the first time decocts 75-95 minute, filter, extract filtrate, the moderate heat that adds water for the second time decocts 45-60 minute, filters, extract filtrate, the big fire that adds water for the third time decocts 20-30 minute, filters, and extracts filtrate, mix three times filtrate, obtain mixed extract;
Step 3: concentrated, dry: mixed extract is concentrated, and the concentrated rear spray dryer that uses is dry, obtains solids mixing extract;
Step 4: pulverize: mixed extract, xylo-oligosaccharide, rock sugar, microcrystalline cellulose are pulverized with pulverizer, after pulverizing, crossed 80 mesh sieves;
Step 5: mix: by weight, mixed extract, xylo-oligosaccharide, rock sugar, microcrystalline cellulose are put into trough type mixing machine, open trough type mixing machine and mix 30 minutes, for subsequent use;
Step 6: granulate: add 70% ethanolic solution in trough type mixing machine, softwood processed, puts into oscillating granulator by softwood, granulation, crosses 80 mesh sieves;
Step 7: dry: by the particle making, be placed in drying box dry, baking temperature is 60 DEG C, takes out for subsequent use.
Step 8: whole grain, pack: take out dried particle, cross 70 mesh sieves, obtain solid particle, by every bag of 2.5g pack, obtain a kind of Radix Glycyrrhizae Qingrejiedu Granules.
In medicine: Radix Glycyrrhizae, clearing heat and detoxicating, moisten the lung and relieve the cough, coordinating the drug actions of a prescription, honey-fried licorice root can be clearing heat and detoxicating, cure mainly abscess of throat, cough, weakness of the spleen and the stomach, stomach, duodenal ulcer, hepatitis, hysteria, carbuncle furuncle poison, medicine and food poisoning, Radix Codonopsis, tonifying middle-Jiao and Qi, invigorating the spleen benefit lung, for a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, interior heat is quenched one's thirst, radix bupleuri, in inducing sweat, soothing the liver, rise sun, for cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official's prolapsus, prolapse of the anus, Ligusticum wallichii, blood-activating and qi-promoting, wind-expelling pain-stopping, for irregular menstruation, through closing dysmenorrhoea, abdominal mass stomachache, the shouting pain of the chest side of body, tumbling and swelling, headache, arthralgia due to wind-dampness, Fructus Corni, tonify the liver and kidney, puckery smart hidroschesis, have a dizzy spell, deaf, spontaneous perspiration, soreness and weakness of waist and knees, impotence, send essence, frequent micturition, the bark of eucommia, filling liver kidney, strengthening the bones and muscles, antiabortive, for lumbago due to the kidney deficiency, muscles and bones is unable, blood leaking in gestation, fetal irritability, hypertension, corydalis tuber, invigorate blood circulation, the loose stasis of blood, regulate the flow of vital energy, pain relieving, the all pains of main trusted subordinate's waist knee, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury, Chinese cassia tree, complement sun, warming spleen and stomach, removing internal cold, promoting blood circulation, control the Yang-function insufficiency of kidneyzang, the cold weak pulse of limb, yang depletion collapse, stomachache is had loose bowels, cold hernia is to globefish, waist knee crymodynia, through closing abdominal mass, cloudy subcutaneous ulcer, streamer, and empty sun is more floating, heat in the upper and cold in the lower, notopterygium root, loose cold, dispel the wind, dehumidifying, pain relieving, for anemofrigid cold headache, arthralgia due to wind-dampness, aching pain in should and back, the root of kudzu vine, rise positive expelling pathogenic factors from muscles and skin, promoting eruption antidiarrheal, relieving restlessness is temperature only, cure the wound cold, warm headache Xiang Qiang, dysphoria with smothery sensation is quenched one's thirst, have loose bowels, dysentery, ecchymosis is not saturating, hypertension, angina pectoris, deaf, Chinese tamarisk tops, dispelling wind, induce sweat, diuresis, removing toxic substances, control measles thoroughly difficult, rubella body is itched, flu, cough and breathe heavily, treating rheumatic ostealgia, Fermented Soybean, de-swelling helps digestion, lowering the adverse-rising QI to resolve phlegm, cure mainly stagnation of QI due to dyspepsia, abdominal fullness and distention, belch.
Beneficial effect of the present invention: a kind of Radix Glycyrrhizae Qingrejiedu Granules of the present invention, to abscess of throat, the main diseases such as cough played in varying degrees clearing heat and detoxicating, moisten the lung and relieve the cough, the effect of coordinating the drug actions of a prescription, has the advantages such as health care, instant effect, pure natural, no side effects.
The present invention is through two groups of clinical verifications, wherein one group is that treatment group is drunk the present invention, and edible the present invention every day once, 7 days is a course for the treatment of, another group control group is taken capsule for clearing away heat, every group selection outpatient 110 examples, wherein male 70 examples, female's 40 examples, maximum 75 years old age, minimal ages 27 years old, used once every day, within 7 days, is a course for the treatment of, clinical manifestation is abscess of throat, cough, weakness of the spleen and the stomach, Stomach duodenum ulcer, hepatitis, hysteria, carbuncle furuncle poison, table one is for taking a contrasting data after the course for the treatment of:
Table 1 is taken two groups of comparisons course for the treatment of in front and back (unit: people)
There were significant differences for treatment group and control group, thereby can find out that the present invention's application clinically has significant curative effect.
Technological advantage of the present invention is: 1, select raw material science, production technology advanced person; 2, in product, do not add spices and anticorrisive agent, keep local flavor and the nutrition of raw material itself, be easily absorbed by the body; 3 raw material sources are extensive, add technique circuit short, the easy processing and manufacturing of product.
Detailed description of the invention
Embodiment 1
A kind of Radix Glycyrrhizae Qingrejiedu Granules, be prepared from Radix Glycyrrhizae 50-60 part, Radix Codonopsis 20-30 part, radix bupleuri 20-30 part, Ligusticum wallichii 20-30 part, Fructus Corni 15-20 part, bark of eucommia 15-20 part, corydalis tuber 15-20 part, Chinese cassia tree 10-15 part, notopterygium root 10-15 part, root of kudzu vine 10-15 part, Chinese tamarisk tops 10-15 part, Fermented Soybean 10-15 part, xylo-oligosaccharide 10-15 part, rock sugar 5-10 part, microcrystalline cellulose 5-10 part by following parts by weight.
Embodiment 2
A kind of Radix Glycyrrhizae Qingrejiedu Granules, be prepared from 60 parts, Radix Glycyrrhizae, 30 parts of Radix Codonopsis, 30 parts of radix bupleuri, 30 parts of Ligusticum wallichiis, 17 parts of Fructus Cornis, 17 parts of the barks of eucommia, 17 parts of corydalis tubers, 15 parts of Chinese cassia trees, 15 parts of notopterygium roots, 15 parts of the roots of kudzu vine, 15 parts of Chinese tamarisk tops, 15 parts of Fermented Soybeans, 10 parts of xylo-oligosaccharides, 10 parts, rock sugar, 10 parts of microcrystalline celluloses by following parts by weight.
Embodiment 3
A kind of Radix Glycyrrhizae Qingrejiedu Granules, be prepared from 55 parts, Radix Glycyrrhizae, 25 parts of Radix Codonopsis, 25 parts of radix bupleuri, 25 parts of Ligusticum wallichiis, 15 parts of Fructus Cornis, 15 parts of the barks of eucommia, 15 parts of corydalis tubers, 13 parts of Chinese cassia trees, 13 parts of notopterygium roots, 13 parts of the roots of kudzu vine, 13 parts of Chinese tamarisk tops, 13 parts of Fermented Soybeans, 12 parts of xylo-oligosaccharides, 8 parts, rock sugar, 8 parts of microcrystalline celluloses by following parts by weight.
Embodiment 4
A kind of Radix Glycyrrhizae Qingrejiedu Granules and preparation method thereof, the key step of its preparation method is:
Step 1: pretreatment of raw material: by weight, choose Radix Glycyrrhizae, Radix Codonopsis, radix bupleuri, Ligusticum wallichii, Fructus Corni, the bark of eucommia, corydalis tuber, Chinese cassia tree, notopterygium root, the root of kudzu vine, Chinese tamarisk tops, Fermented Soybean, clean and removal of impurities, for subsequent use;
Step 2: prepare mixed extract: Radix Glycyrrhizae, Radix Codonopsis, radix bupleuri, Ligusticum wallichii, Fructus Corni, the bark of eucommia, corydalis tuber, Chinese cassia tree, notopterygium root, the root of kudzu vine, Chinese tamarisk tops, Fermented Soybean are mixed, and then water decocts three times, the little fire that adds water for the first time decocts 75-95 minute, filter, extract filtrate, the moderate heat that adds water for the second time decocts 45-60 minute, filters, extract filtrate, the big fire that adds water for the third time decocts 20-30 minute, filters, and extracts filtrate, mix three times filtrate, obtain mixed extract;
Step 3: concentrated, dry: mixed extract is concentrated, and the concentrated rear spray dryer that uses is dry, obtains solids mixing extract;
Step 4: pulverize: mixed extract, xylo-oligosaccharide, rock sugar, microcrystalline cellulose are pulverized with pulverizer, after pulverizing, crossed 80 mesh sieves;
Step 5: mix: by weight, mixed extract, xylo-oligosaccharide, rock sugar, microcrystalline cellulose are put into trough type mixing machine, open trough type mixing machine and mix 30 minutes, for subsequent use;
Step 6: granulate: add 70% ethanolic solution in trough type mixing machine, softwood processed, puts into oscillating granulator by softwood, granulation, crosses 80 mesh sieves;
Step 7: dry: by the particle making, be placed in drying box dry, baking temperature is 60 DEG C, takes out for subsequent use.
Step 8: whole grain, pack: take out dried particle, cross 70 mesh sieves, obtain solid particle, by every bag of 2.5g pack, obtain a kind of Radix Glycyrrhizae Qingrejiedu Granules.

Claims (5)

1. a Radix Glycyrrhizae Qingrejiedu Granules, it is characterized in that: be prepared from Radix Glycyrrhizae 50-60 part, Radix Codonopsis 20-30 part, radix bupleuri 20-30 part, Ligusticum wallichii 20-30 part, Fructus Corni 15-20 part, bark of eucommia 15-20 part, corydalis tuber 15-20 part, Chinese cassia tree 10-15 part, notopterygium root 10-15 part, root of kudzu vine 10-15 part, Chinese tamarisk tops 10-15 part, Fermented Soybean 10-15 part, xylo-oligosaccharide 10-15 part, rock sugar 5-10 part, microcrystalline cellulose 5-10 part by following parts by weight.
2. a kind of Radix Glycyrrhizae Qingrejiedu Granules according to claim 1, it is characterized in that: be prepared from 60 parts, Radix Glycyrrhizae, 30 parts of Radix Codonopsis, 30 parts of radix bupleuri, 30 parts of Ligusticum wallichiis, 17 parts of Fructus Cornis, 17 parts of the barks of eucommia, 17 parts of corydalis tubers, 15 parts of Chinese cassia trees, 15 parts of notopterygium roots, 15 parts of the roots of kudzu vine, 15 parts of Chinese tamarisk tops, 15 parts of Fermented Soybeans, 10 parts of xylo-oligosaccharides, 10 parts, rock sugar, 10 parts of microcrystalline celluloses by following parts by weight.
3. a kind of Radix Glycyrrhizae Qingrejiedu Granules according to claim 1, it is characterized in that: be prepared from 55 parts, Radix Glycyrrhizae, 25 parts of Radix Codonopsis, 25 parts of radix bupleuri, 25 parts of Ligusticum wallichiis, 15 parts of Fructus Cornis, 15 parts of the barks of eucommia, 15 parts of corydalis tubers, 13 parts of Chinese cassia trees, 13 parts of notopterygium roots, 13 parts of the roots of kudzu vine, 13 parts of Chinese tamarisk tops, 13 parts of Fermented Soybeans, 12 parts of xylo-oligosaccharides, 8 parts, rock sugar, 8 parts of microcrystalline celluloses by following parts by weight.
4. according to a kind of Radix Glycyrrhizae Qingrejiedu Granules described in claim 1-3 and preparation method thereof, it is characterized in that: the key step of its preparation method is:
Step 1: pretreatment of raw material: by weight, choose Radix Glycyrrhizae, Radix Codonopsis, radix bupleuri, Ligusticum wallichii, Fructus Corni, the bark of eucommia, corydalis tuber, Chinese cassia tree, notopterygium root, the root of kudzu vine, Chinese tamarisk tops, Fermented Soybean, clean and removal of impurities, for subsequent use;
Step 2: prepare mixed extract: Radix Glycyrrhizae, Radix Codonopsis, radix bupleuri, Ligusticum wallichii, Fructus Corni, the bark of eucommia, corydalis tuber, Chinese cassia tree, notopterygium root, the root of kudzu vine, Chinese tamarisk tops, Fermented Soybean are mixed, and then water decocts three times, the little fire that adds water for the first time decocts 75-95 minute, filter, extract filtrate, the moderate heat that adds water for the second time decocts 45-60 minute, filters, extract filtrate, the big fire that adds water for the third time decocts 20-30 minute, filters, and extracts filtrate, mix three times filtrate, obtain mixed extract;
Step 3: concentrated, dry: mixed extract is concentrated, and the concentrated rear spray dryer that uses is dry, obtains solids mixing extract;
Step 4: pulverize: mixed extract, xylo-oligosaccharide, rock sugar, microcrystalline cellulose are pulverized with pulverizer, after pulverizing, crossed 80 mesh sieves;
Step 5: mix: by weight, mixed extract, xylo-oligosaccharide, rock sugar, microcrystalline cellulose are put into trough type mixing machine, open trough type mixing machine and mix 30 minutes, for subsequent use;
Step 6: granulate: add 70% ethanolic solution in trough type mixing machine, softwood processed, puts into oscillating granulator by softwood, granulation, crosses 80 mesh sieves;
Step 7: dry: by the particle making, be placed in drying box dry, baking temperature is 60 DEG C, dry rear taking-up is for subsequent use.
5. step 8: whole grain, pack: take out dried particle, cross 70 mesh sieves, obtain solid particle, by every bag of 2.5g pack, obtain a kind of Radix Glycyrrhizae Qingrejiedu Granules.
CN201410681268.6A 2014-11-25 2014-11-25 Licorice electuary for clearing heat and detoxifying as well as preparation method thereof Pending CN105596434A (en)

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Application Number Priority Date Filing Date Title
CN201410681268.6A CN105596434A (en) 2014-11-25 2014-11-25 Licorice electuary for clearing heat and detoxifying as well as preparation method thereof

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CN105596434A true CN105596434A (en) 2016-05-25

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Application publication date: 20160525