CN105582151A - Prunella vulgaris health-care oral liquid for cooling blood and clearing away toxic materials and preparation method thereof - Google Patents

Prunella vulgaris health-care oral liquid for cooling blood and clearing away toxic materials and preparation method thereof Download PDF

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CN105582151A
CN105582151A CN201510753514.9A CN201510753514A CN105582151A CN 105582151 A CN105582151 A CN 105582151A CN 201510753514 A CN201510753514 A CN 201510753514A CN 105582151 A CN105582151 A CN 105582151A
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selfheal
blood
oral liquid
health care
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不公告发明人
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Qingdao Anbeikang Biomedical Technology Co Ltd
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Qingdao Anbeikang Biomedical Technology Co Ltd
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Abstract

The invention provides prunella vulgaris health-care oral liquid for cooling blood and clearing away toxic materials. The oral liquid is prepared from, by weight, 10-50 parts of prunella vulgaris, 10-20 parts of herba ecliptae, 10-20 parts of centella asiatica, 10-20 parts of peach kernels, 10-20 parts of red peony roots, 10-20 parts of sophora flowers, 10-20 parts of trollflowers, 10-20 parts of raspberry fruit, 10-20 parts of rehmannia glutinosa libosch, 10-20 parts of cortex moutan, 10-20 parts of gardenia jasminoides ellis, 10-20 parts of herba leonuri, 10-20 parts of calendula officinalis, 10-20 parts of radix polygoni multiflori preparata, 10-20 parts of flowers of silk tree albizzia, 10-20 parts of caulis spatholobi, 10-20 parts of sculellaria barbata and 10-20 parts of portulacae herba. According to the prunella vulgaris health-care oral liquid, the modern nutriology theory and the traditional Chinese medicine health-care theory are organically combined, the functional activities of viscera are normal, qi and blood are smooth, all qi functions are achieved, yin and yang are in balance, qi is benefited and blood is activated, the bowels are relaxed, the detoxifying function is achieved, and therefore the dual purposes of detoxifying and face beautifying are achieved.

Description

Selfheal health care oral liquid of a kind of cool blood toxin expelling and preparation method thereof
Technical field
The present invention relates to contain the medical health product that derives from plant, animal or raw mineral materials, particularly selfheal health care oral liquid of a kind of cool blood toxin expelling and preparation method thereof.
Background technology
Environmental pollution is day by day serious, and modern more and more payes attention to the health of self toxin-expelling and face nourishing, and expert points out to only have harmful substance and superfluous nutrition in timely eliminating body, keeps clean in the five internal organs and body, could keep the fitness of health and the beauty of skin. So which kind of poisoning crowd must note good in giving health toxin expelling oneself is, then oneself is suited the remedy to the case, and finds the toxin-expelling and face nourishing way that is applicable to oneself, so just can reach toxin-expelling and face nourishing object.
The selected food of toxin-expelling and face nourishing and eating method are all very simple. In general, the every meal of normal person is eaten a fruits, two portions of vegetables, a Ipomoea batatas, a staple food, and every part of size is determined by individual appetite, as long as in perspective. Collocation moderate exercise just can meet the toxin expelling needs of general beauty, but for self functions of expelling toxin, the effect that more contributes to a bit intestines peristalsis, cleaning enteron aisle rubbish toxin is drunk in slightly poor maiden's suggestion collocation in motion and allotment diet, reaches quick toxin expelling, beautifying face and moistering lotion effect.
Middle-aged women ties down up and down, can't bear the heavy load, and this does not also include, and " tie down centre " is sader. The traditional Chinese medical science is thought the mechanism yin and yang imbalance nothing more than of women's aging, and qi-blood disharmony, ascending or descending movement of vital Qi is come in and gone out not normal, visceral dysfunction. Women will learn love oneself, unobstructed health, thereby unobstructed psychology, and regular discharge vivotoxin, adjusts fuselage state and can lay a solid foundation for the beauty of today and the health of tomorrow undoubtedly.
1. the promotion toxin expellings that drink water more. Excretion is one of important method of human detoxification, drinks foot 2 premium on currency every day and can rinse the toxin in body, alleviates the burden of kidney, is the natural and the easiest method of toxin expelling. In daily life, do not wait until that thirsty just going drink water, in the gap of work, drink glass water and have a rest, refresh oneself, more spiritedness proceeds with one's work also. WA is drunk warm water in the morning, can also promote stool and urine to get rid of, and has the effect of cleaning large intestine and small intestine.
2. the cellulosic foods of eating promote toxin expelling more. Constipation is the key factor that affects toxin expelling, and stool why can to stay in human body be exactly that wriggling ability because of enteron aisle is inadequate, be rich in cellulosic food if eaten at ordinary times, such as brown rice, vegetables, fruit more, particularly aloe, prune etc., just can help defecation. In addition, diet collocation is natural also can help woman to get rid of stool, and cleaning enteron aisle is greasy, beauty treatment weight reducing. Be rich in cellulose or chlorophyllous food also has function of detoxification, eat the toxicant that contributes to eliminate cylinder accumulation more, before toxicant is got rid of by intestinal absorption by liver, allow it be attached on fiber food and chlorophyll, and along with stool eliminating is external, can reduce the build-up effect of toxicant. There is the food of effect like this successively, rice bran, spinach and radish leaf.
3. the fruit of eating promotes toxin expelling more. The effect of the large helpful body removing toxic substances of fresh fruit and toxin expelling, is called as in body " cleaning agent ", often eats fruit and can will accumulate on intracellular toxin dissolution, the effect of internal organs, balance neutrality physique in playing and in body inner acidic toxin, purification body. Its profoundness is that fruit has one " wuwa "---alkaline components, and fruit drink enters in body and after digestive system, can make blood be alkalescence, and dissolution precipitation, in intracellular toxin, makes it to fall with urine drains, contributes to remove toxin and the refuse in body, piled up. And the general heat of fruit is lower, do not have the danger of getting fat.
Human body is " flesh and blood ". Only have qi and blood foot, just seem that skin is ruddy, face is glossy; Only have meat real, just can have muscular, build fitness. For women, pursue face gorgeous, stature is gentle and graceful, should focus on and nourish blood. Woman's Yangxuemeiyan is achieved gentle and graceful stature because female pathology has the feature that " cycle " hematozemia is many, sets up their relationship with blood. Traditional Chinese medicine is pointed out for a long time: " women is to nourish blood as this. " if women is bad to nourish blood, and just easily occurs sallow complexion, lip and nail are pale, limb is puckery, send out withered, dizziness, dim eyesight, the deficiency of blood disease such as weak, out of breath, i.e. anaemia. The early ageing symptoms such as wrinkle, white hair, debentition also occur serious anaemia person very easily too early, walk haltingly. Visible, women nourishes blood extremely urgent.
Selfheal is the dry fruit ear of labiate selfheal PrunellavulgarisL.. All produce all parts of the country, main product in Jiangsu, the ground such as Zhejiang, Anhui, Henan. When summer, fruit ear was brownish red, gather, remove impurity, dry. Raw using. Its property is pungent, bitter, cold. Return liver, gallbladder channel. There is clearing heat-fire, improving eyesight, effect of mass dissipating and swelling eliminating.
Treatment red eye, swell pain, dizzy, the order pearl nyctalgia of having a headache. Selfheal bitter cold master enters Liver Channel, and kind purge the green is with improving eyesight. With controlling liver-fire flaming, red eye, swell pain, can join mulberry leaf, chrysanthemum, cassia seed etc. medicinal. Among this product is clear liver and improved vision, the nourishing the liver of slightly holding concurrently, joins Radix Angelicae Sinensis, the fruit of Chinese wolfberry, can be used for deficiecny of liver-YIN, and ophthalmalgia, to more so person at night; Also can accessory stick up, Radix Glycyrrhizae use, as loose in selfheal (" Zhang Shi doctor is logical ").
Treatment scrofula, goiter and tumor. This taste is pungent can dissipating bind, and bitter cold can expel the heat-evil, and often joins the bulb of fritillary, the capsule of weeping forsythia etc. medicinal to control liver depression forming fire, and the scrofula of convulsive seizure due to phlegm-fire cohesion, as selfheal soup (" surgery orthodox school "); With controlling goiter and tumor, often join the use such as kelp, radix scrophulariae, as selfheal cream (Golden Mirror of Medicine).
Treatment acute mastitis swells and ache. This product can heat-clearing be gone irascibility, again can mass dissipating and swelling eliminating, and can control acute mastitis and swell and ache, normal and dandelion are with (" book on Chinese herbal medicine converges and says "). If join honeysuckle, can control pathopyretic ulcer, as detoxicating pill (" blue or green capsule is secretly handed down ").
Shennong's Herbal carries it: " main fever and chills, scrofula, mouse fistula, a sore, broken disease. Loose goitre knot gas, the pin arthritis with fixed pain caused by dampness that swells. " Compendium of Material Medica carries it: " selfheal is controlled order pain, with granulated sugar water logging one ight, gets it and can separate interior heat, and slow irascibility is also. Lou Quan is apt to cloud, and selfheal controls that order pearl ached to night what for person, the magical effect, or by instead very person, the also magical effect of bitter cold snack made with traditional Chinese medicines. Lid order pearl connects order originally, and liver is also, belongs to the warp of the moon of fainting. Night very and anti-person very of some bitter and cold medicines, therefore night with cold also cloudy also. The gas of the pure sun of withered official report of summer, mends the cloudy blood vessels of fainting, thus control this as god, with Yang Zhiyin also. " " notes of Chongqing hall " son rise " grass, micro-pungent and sweet, therefore among dissipating bind, have concurrently and the merit of positive yin-nourishing, the sleeping of the person's of being insomnia clothes after losing blood, its property is visible. Chen Jiuzhe is especially sweet, is used as medicine for victory. "
Pharmacological research
1. chemical composition: this product contains the glycoside materials such as triterpenoid saponin, rutin sophorin, Hyperoside and ursolic acid, caffeic acid, the organic acids such as oleanolic acid dissociate; Hua Suizhong is containing the anthocyanin of delphinidin, Cyanidin, d-camphor, d-fenchone etc.
2. pharmacological action: this product decoction, water-leach liquor, alcohol-water leachate and alcohol leaching liquid all can obviously reduce animal used as test blood pressure, and stem, leaf, fringe and herb all have hypotensive effect, but the effect of fringe is more obvious; The injection of this product water decoction-alcohol sedimentation liquid mouse peritoneal, has obvious antiinflammatory action; This product decoction all has certain inhibitory action to shigella dysenteriae, typhoid bacillus, comma bacillus, Escherichia coli, proteus, staphylococcus and Bacillus tuberculosis in vitro.
3. clinical research: in conjunction with being used for the treatment of headache, dizzy traditionally, pharmacological research has hypotensive activity, and modern clinic, in order to Hypertension, helps step-down; Get its mass dissipating and swelling eliminating and conventional control thyroid gland enlargement, enlargement of lymph nodes, the proliferation of mammary gland, hypertension etc. and belong to the hot person of liver; With selfheal, oldenlandia diffusa, cogongrass rhizome, Radix Glycyrrhizae, Radix Isatidis, subprostrate sophora, be decocted in water for oral dose, treatment chronic hepatitis B 50 examples, cure 33 examples, and 12 examples take a turn for the better; With selfheal, bletilla, grind to the powder altogether, lard adjusts cream to apply affected part, controls rhagadia manus et pedis 36 examples, recovery from illness 34 examples; Use selfheal 100g, decocting 2 times, foam washing both hands, treatment hand desquamation is demonstrate,proved over one hundred example, all recovery from illness.
Selfheal compatibility Radix Angelicae Sinensis, root of herbaceous peony selfheal clearing liver scattered silt; Radix Angelicae Sinensis, the root of herbaceous peony are nourished blood and enrich blood. and three's compatibility is with there being the effect of separating liver depression, nourishing the liver blood to be used for the treatment of all diseases due to hepatic depression and blood deficiency.
The clearing away the liver-fire of selfheal compatibility chrysanthemum selfheal, flat liver-yang; The cool liver of chrysanthemum heat-clearing. Papillary has that the merit of clearing liver, cool liver, flat liver is used for the treatment of liver-fire flaming, wind-heat of liver channel causes red eye, swell pain; Or the headache that causes of liver-yang hyperactivity, dizzy.
Selfheal compatibility kelp, marine alga selfheal clearing away the liver-fire Disperse hepatic depression; Kelp, the equal dispelling phelgm to soften abdominal mass of marine alga and Li Shui. Effect that three medicines have share the dissipating bind of relieving inflammation or internal heat, dispelling phelgm to soften abdominal mass is used for the treatment of the scrofula due to irascibility phlegm knot.
Selfheal compatibility radix scrophulariae, the clearing away the liver-fire of capsule of weeping forsythia selfheal and Disperse hepatic depression; Radix scrophulariae quench dissipating bind; Capsule of weeping forsythia detoxicating and resolving a mass. three strengthens and is used for the treatment of the convulsive seizure due to phlegm-fire scrofula of knot mutually with the power by its dissipating bind of relieving inflammation or internal heat.
Chinese medicine odor poverty, a lot of people are reluctant long-term taking; Even if take, be three points of poison of medicine, while allowing people's long-term taking, also produce resisting psychology. How the cool blood toxin expelling efficacy exertion of selfheal not being injured again to human body to maximum, and obviously improve mouthfeel, people can be accepted, is our problem in the urgent need to address. Human body is " flesh and blood ". Only have hemapodium, the skin that just seems is ruddy, and face is glossy, only has meat real, just can have muscular, build fitness. For women, pursue face gorgeous, stature is gentle and graceful, should focus on and nourish blood. Woman's Yangxuemeiyan is achieved gentle and graceful stature because female pathology has the feature that " cycle " hematozemia is many, sets up their relationship with blood. Traditional Chinese medicine is pointed out for a long time: " women is to nourish blood as this. " if women is bad to nourish blood, and just easily occurs sallow complexion, lip and nail are pale, limb is puckery, send out withered, dizziness, dim eyesight, the deficiency of blood disease such as weak, out of breath, i.e. anaemia. The early ageing symptoms such as wrinkle, white hair, debentition also occur serious anaemia person very easily too early, walk haltingly. Visible, women nourishes blood extremely urgent. So, how woman should carry out toxin-expelling and face nourishingThat traditional Chinese medicine health care product has advantages of is nontoxic, can be absorbed completely by organism, is the main direction that we study.
Summary of the invention
Technical problem to be solved by this invention is, modern's rhythm of life is quick, self health cannot looked after traditionally, detoxifying health-care product has become our one Gospel, research shows, there is water wing, little tripe sirloin, the women of the problems such as underbelly proud flesh has enterotoxin in various degree to pile up problem. People are general abroad selects product natural, that have no side effect to solve Similar Problems. So which kind of poisoning crowd must note good in giving health toxin expelling oneself is, then oneself is suited the remedy to the case, and finds the toxin-expelling and face nourishing way that is applicable to oneself, so just can reach toxin-expelling and face nourishing object.
For solving the problems of the technologies described above, the invention provides a kind of selfheal health care oral liquid of cool blood toxin expelling, described in it, health care oral liquid comprises the bulk drug of following parts by weight: 10~50 parts of selfheals, 10~20 parts of ecliptas, 10~20 parts of centellas, 10~20 parts, peach kernel, 10~20 parts of the radix paeoniae rubrathe, 10~20 parts, sophora flower, 10~20 parts of trollflowers, 10~20 parts of raspberries, 10~20 parts, the dried rhizome of rehmannia, 10~20 parts of the root barks of tree peony, 10~20 parts of cape jasmines, 10~20 parts of motherworts, 10~20 parts of pot marigolds, 10~20 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 10~20 parts of Flos Albiziaes, 10~20 parts of reticulate millettias, 10~20 parts of Sculellaria barbatas, 10~20 parts of purslanes.
The selfheal health care oral liquid of described cool blood toxin expelling, described in it, health care oral liquid can comprise the bulk drug of following parts by weight: 10~30 parts of selfheals, 10~15 parts of ecliptas, 10~15 parts of centellas, 10~15 parts, peach kernel, 10~15 parts of the radix paeoniae rubrathe, 10~15 parts, sophora flower, 10~15 parts of trollflowers, 10~15 parts of raspberries, 10~15 parts, the dried rhizome of rehmannia, 10~15 parts of the root barks of tree peony, 10~20 parts of cape jasmines, 10~20 parts of motherworts, 10~20 parts of pot marigolds, 10~20 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 10~20 parts of Flos Albiziaes, 10~20 parts of reticulate millettias, 10~20 parts of Sculellaria barbatas, 10~20 parts of purslanes.
The selfheal health care oral liquid of described cool blood toxin expelling, described in it, health care oral liquid can also comprise the bulk drug of following parts by weight: 10~40 parts of selfheals, 10~20 parts of ecliptas, 10~20 parts of centellas, 10~20 parts, peach kernel, 10~20 parts of the radix paeoniae rubrathe, 10~20 parts, sophora flower, 10~20 parts of trollflowers, 10~20 parts of raspberries, 10~20 parts, the dried rhizome of rehmannia, 10~20 parts of the root barks of tree peony, 10~15 parts of cape jasmines, 10~20 parts of motherworts, 10~20 parts of pot marigolds, 10~20 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 10~20 parts of Flos Albiziaes, 10~20 parts of reticulate millettias, 10~20 parts of Sculellaria barbatas, 10~20 parts of purslanes.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of selfheal health care oral liquid of cool blood toxin expelling, and described in it, the preparation process of selfheal health care oral liquid comprises following aspect:
A. gather when selfheal fruit ear is brownish red when summer, remove impurity, dry, raw using;
B. the selfheal of drying being pulverized, soaked ethanol heating extracts;
C. alcohol extract is pulverized, soaked to described other raw materials;
D. other raw material extracts are mixed with the selfheal extract preparing and concentrate, sterilizing is prepared into oral solutions.
In described step a, can be between the 6-8 month, in the time that selfheal fruit ear is brownish red, harvesting, airing, allow it parch, for subsequent use.
In described step b, selfheal chopping can be placed in 70-90% ethanol and soak 1-2 hour, in water-bath, be heated to 60 DEG C-70 DEG C, lixiviate 2h, every 10min stirs once, by filtered through gauze, adds 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, every 10min stirs once, and filtered through gauze merges leaching liquor, be condensed into pasty state filtrate, stand-by.
In described step c, all the other raw materials can be cleaned to impurity elimination, put into 10 times of amount ethanol, soak 1-2 hour, heating is extracted 2 times, each 1-2 hour, remove supernatant, merge extract, 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams again, 1.05 filtrate when ultrafiltrate reduced pressure concentration relative density is 80 DEG C.
In described steps d, two kinds of extracts can be inserted in economic benefits and social benefits vacuum concentrator to the concentrate that while being concentrated into 90 DEG C, relative density is 1.25, set to 0~5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g crude drug amount, disappears through ultraviolet rayPoisoningAfter bacterium, bottle.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of selfheal health care oral liquid of cool blood toxin expelling, and the preparation process of described selfheal health care oral liquid can also comprise following aspect:
A. gather when selfheal fruit ear is brownish red when summer, remove impurity, dry, raw using;
B. the selfheal of drying is pulverized, soaked ethanol and add extraction heat;
C. alcohol extract is pulverized, soaked to described other raw materials;
D. other raw material extracts are mixed with the selfheal extract preparing and concentrate, sterilizing is prepared into oral solutions.
In described step b, the extraction step of selfheal can be: get selfheal for subsequent use chopping, steep in the ethanol that 5-10 doubly measures, medicinal powder is equipped with and is covered in stainless steel cask, add 70% ethanol, the 0.8-1 that quality is meal doubly, stir, moistening airtight placement more than 1 hour, makes abundant expansion; After percolator bottom filter plate is paved with gauze bag parcel, again the drug sample after moistening expansion is mixed to pine and done loose, then contain powder with stainless steel spoon, pack uniformly percolator into, dress 10-12 cm thick, press evenly with T-shaped rod, then press aforesaid operations, packing in layer, suitably pressurization, medicinal powder must not load and exceeded 2/3 eminence of percolator; Medicinal powder face upper cover stainless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, then slowly adds 70% ethanol; Air between medicinal powder powder to be discharged, and there is ethanol to flow out about 20L left and right, close baiting valve, cover the cylinder of filtering, dipping 24 hours, then open baiting valve and carry out diacolation, control diacolation speed and be generally 1000g medicinal material outflow 2~3ml per minute, filtrate is put into liquid container, and ethanol when emptying is poured liquid container into; Percolate is merged and left standstill.
The present invention organically combines with Chinese Traditional Medicine health care is theoretical theoretical modern nutriology, can invigorating qi and benefiting blood, and enriching yin and nourishing kidney, freckle removing and whitening. Traditional Chinese medicine is pointed out for a long time: " women is to nourish blood as this. " if women is bad to nourish blood, and just easily occurs sallow complexion, lip and nail are pale, limb is puckery, send out withered, dizziness, dim eyesight, the deficiency of blood disease such as weak, out of breath, i.e. anaemia. The early ageing symptoms such as wrinkle, white hair, debentition also occur serious anaemia person very easily too early, walk haltingly. Visible, women nourishes blood extremely urgent. The advantage that Chinese medicine toxic side effect is little, Chinese medicine health-care treatment causes extensive concern. How to get through human detoxification pipeline, by toxin expelling main pipeline---alimentary canal is discharged vivotoxin, and by the combination of logical benefit, the exquisite prescription compatibility of medicines such as lifting is proper, with the conditioning metabolism of human disorder and the endocrine of imbalance, regulate fuselage state balance, make function activity normal, qi and blood smoothness, mechanism of qi bar reaches, equilibrium between yin and yang, qi and activate blood circulation, catharsis and toxin expelling, thus reach the dual purpose of toxin expelling and beauty treatment. From the angle of body structure, toxin expelling is the adjustment to whole toxin expelling system, comprises the conditioning to human-body viscera function, the dredging of the toxin expelling pipelines such as blood vessel, lymphatic vessel, tracheae, the urinary tract, digester tube, the adjusting to QI-blood circulation etc. The present invention row, the system of separating, adjusting, mending quaternity, scientifically application is the combination of traditional Chinese medical science science, method, prescription, drugs. Make function activity normal, qi and blood smoothness, mechanism of qi bar reaches, equilibrium between yin and yang, qi and activate blood circulation, catharsis and toxin expelling, thus reach the dual purpose of toxin expelling and beauty treatment.
Detailed description of the invention
Environmental pollution is day by day serious, and modern more and more payes attention to the health of self toxin-expelling and face nourishing, and expert points out to only have harmful substance and superfluous nutrition in timely eliminating body, keeps clean in the five internal organs and body, could keep the fitness of health and the beauty of skin. How to get through human detoxification pipeline, by toxin expelling main pipeline---alimentary canal is discharged vivotoxin, and by the combination of logical benefit, the exquisite prescription compatibility of medicines such as lifting is proper, with the conditioning metabolism of human disorder and the endocrine of imbalance, regulate fuselage state balance, make function activity normal, qi and blood smoothness, mechanism of qi bar reaches, equilibrium between yin and yang, qi and activate blood circulation, catharsis and toxin expelling, thus reach the dual purpose of toxin expelling and beauty treatment. From the angle of body structure, toxin expelling is the adjustment to whole toxin expelling system, comprises the conditioning to human-body viscera function, the dredging of the toxin expelling pipelines such as blood vessel, lymphatic vessel, tracheae, the urinary tract, digester tube, the adjusting to QI-blood circulation etc. The present invention row, the system of separating, adjusting, mending quaternity, scientifically application is the combination of traditional Chinese medical science science, method, prescription, drugs. Toxin expelling---be the new performance that modern selects healthy living, it is important that healthy beyond all else comes, so toxin expelling also becomes one in people's daily life and pursues greatly. Extremely important, the good beginning of toxin expelling product choosing, can save a lot of unnecessary troubles, and health can not trifling matter.
Woman's health allows and oneself becomes more healthy and beautiful, and many woman understand and need to after busy, maintain oneself by variety of way, but when taking action, we but usually easily go onMistakeRoad. Woman wants health, and first thing is enriched blood from nourishing blood exactly, color has been got well, women's healthy talking of just having. It is exactly taking blood as use that woman maintains the first step, because the physilogical characteristics such as women's menstruation, tire are pregnant, delivery and feed infant and lactation are all easily consumed blood, so the relatively easy state in blood system deficiency of women's body. Say as " a Ling Shu Miraculous Pivot or Divine Axis five flavours and five notes of traditional Chinese music section ": " women's life, has a surplus in gas, is not enough to blood, counts collapse due to massive hemorrhage also with it. So ", first female health preserving should pay attention to maintaining qi and blood. That hemapodium just can make to have rosy cheeks is beautiful, menses normal, spirit is vigorous. Nourish blood if be bad at, just easily occur that sallow complexion is simple and unadorned, lip and nail are pale, dizzy, lassitude hypodynamia, send out withered limb fiber crops,, menstrual period delay few through blood volume, the light arteries and veins of tongue are thin etc. When serious anaemia, also easily occur wrinkle early raw, grey hair early white, climacteric the early ageing situation such as in advance.
Women, because its physiology has the feature that cycle hematozemia is many, nourishes blood if be bad at, and just easily occurs sallow complexion, lip and nail are pale, limb is puckery, send out withered, dizziness, dim eyesight, the deficiency of blood disease such as weak, out of breath. Serious anaemia person, the early ageing symptom such as wrinkle, white hair, debentition also occur very easily too early, walk haltingly. Hemapodium, skin could be ruddy, and complexion is just glossy, if it is beautiful that women will pursue face, stature is gentle and graceful, must pay attention to nourishing blood, and nourishes blood and will note the following aspects: god reposes happy, have a bright and cheerful disposition, not only can promote the immunity of body, and be conducive to physical and mental health, can also promote that the hemopoietic function of bone marrow in health bone is vigorous simultaneously, make skin ruddy, face is glossy. So, the mood that should often keep pleasant.
Modern people's living and diet is too meticulous, and amount of exercise reduces, or eats and drinks immoderately, or overstrain, and body metabolism function is failed gradually, causes visceral dysfunction, easily causes the pigmented lesion such as chloasma faciei, freckle. The traditional Chinese medical science thinks, facial colour spot is uncomfortable because of internal organs meridian qi and blood, and the deficiency of blood is not dissolved in face; Or because of inernal injuries caused by seven emotions, stagnation of QI due to depression of the liver, incoordination between the liver and the spleen; Or because of improper diet and overtiredness, irregular menstruation; Or because of the blood system of the strongly fragrant channels and collaterals of fire, ailment said due to cold or exposure is rich and due to sending out outward. Adopt this class disease of western medicine, be mostly outer wiping or vitamins for oral administration, flavonols medicine. Because pathogenesis is more, adopt western medicine effect to differ, be also difficult for radical cure, some medicine side effect is larger.
Selfheal herb contains the triterpenoid saponin taking oleanolic acid (Oleanolicacid) as aglycon. Still contain the glycoside material such as rutin sophorin (Rutin), Hyperoside (Hyperoside). also contain the organic acids such as ursolic acid (Ursolicacid), caffeic acid (Caffeicacid) and free oleanolic acid. still containing inorganic salts such as vitamin B1, vitamin C, vitamin K, carrotene, resin, amaroid, tannin, volatile oil, alkaloid and potassium chloride.
Hua Suizhong is containing the anthocyanin of delphinidin (Delphinidin) and Cyanidin (Cyanidin), d-camphor (d-Camphor), d-fenchone (d-Fenchone), ursolic acid, fruit ear is containing ursolic acid (ursolicacid), oleanolic acid (oleanolicacid), ursolic acid and oleanolic acid are the saponin of main glucoside unit, Daucosterol (daucosterol), β-amyrin (β-mayrin) and its lignoceric acid (tetra-cosanicacid), 20 produce alkanoic acid (hexacosanicacid), the ester of octocosoic acid (octa-cosanicacid) and melissic acid (triacontanicacid).
Herb is containing many grain of acidity Polysaccharides from Prunella vulgaris L (prunellin) of tool anti human immune deficiency virus (HIV), also containing oleanolic acid, ursolic acid, oleanolic acid is the saponin of glucoside unit, rutin (rutin), hyperin (hyperoside), caffeic acid (caffeicacid), vitamin (vitamins) C, D, D carrotene (carotene), tannin (tan-nin), and thing sense (alkaloids) and volatile oil, wherein contain levo-camphor (camphor), dextrorotation fenchone (fenchone).
Modern study
To the effect of cardiovascular system
(concentration is 1: 10 ten thousand~1 to selfheal decoction: 1,000,000) can make the rabbit heart in place and isolated frog heart shrinkage amplitude increase, make shrinkage amplitude diminish but concentration increases (1: 20~1: 50).
Water-leach liquor, ethanol water-leach liquor and 30% ethanol extract of selfheal, give anesthetized animal lumbar injection, intravenous injection or the oral effect that all reduces blood pressure, intravenous injection hypotensive effect is obvious, oral administration hypotensive effect is faint. and decoction (100mg/kg) is injected in anesthetized dog, can produce significantly lasting hypotensive effect, but there is tachylaxis, after vagotomy, its hypotensive effect obviously weakens. to renal hypertension dog, take medicine continuously after 2 weeks, blood pressure has moderate reduction, returns to again originally level after drug withdrawal. Selfheal stem, leaf, fringe and herb all have hypotensive effect, a little less than the effect of fringe.
Resisting pathogenic microbes effect experiment in vitro shows: selfheal decoction all has certain inhibitory action to shigella dysenteriae, typhoid bacillus, comma bacillus, Escherichia coli, proteus, Pseudomonas aeruginosa and staphylococcus, streptococcus and Bacillus tuberculosis.
Selfheal can make the pulmonary lesion of experimental tuberculosis mouse alleviate to some extent. Selfheal fresh goods is squeezed the juice all has inhibitory action to staphylococcus aureus, beta hemolytic streptococcus, Escherichia coli, typhoid bacillus, shigella dysenteriae, corynebacterium diphtheriae, bacillus anthracis, Pseudomonas aeruginosa.
Water logging agent (1: 4) is also had inhibitory action in various degree to permitting some common pathogenic dermatophyte such as blue achorion, Du's big belly microspore achorion difficult to understand in vitro.
Immunosuppressive action
Experiment shows: selfheal parenteral solution 6g (crude drug)/kg hypodermic injection, can make cavy, mouse adrenal gland obviously increase, thymus gland, the obvious atrophy of spleen. Selfheal water decoction-alcohol sedimentation liquid (1: 1) intramuscular injection 3g (crude drug)/kg, can make adult rat adrenal tissue weight increase, and Thymus and spleen weight saving, the wherein remarkable atrophy of thymus gland, compared with control group, on average alleviates 63.4%. In addition, still can make the institutional framework of adrenal cortex, thymus gland and spleen change to some extent.
Selfheal decoction (1: 50~1: 200) can make rabbit isolated uterine occur tetanic contraction. To isolated rabbit intestines, high concentration can strengthen it wriggles, and the most responsive with duodenum, ileum sensitiveness is poor. Once had report, 100% selfheal decoction can suppress the growth of mouse S180 and EC, but the death rate instead more not administration group is higher.
Selfheal water decoction-alcohol sedimentation liquid all has inhibitory action to mouse knoting oil ear swelling and the swelling of rat yeast toes.
The pungent micro-hardship of rhizoma cyperi is sweet, and flat function cures mainly: the Xie Yu that regulates the flow of vital energy, menstruction regulating and pain relieving. For stagnation of QI due to depression of the liver, chest, the side of body, abdominal distention, indigestion, irregular menstruation, through closing dysmenorrhoea, cold hernia stomachache, swollen breasts. " detailed outline " carries it: the cold epidemic disease of gas when loose, and sharp three warmers, Xie Liuyu, the diet that disappears gathers, and phlegm and retained fluid ruffian is full, and instep is swollen, abdominal distension, beriberi, only trusted subordinate, limbs, head, order, tooth, all pains of ear, ulcer sores, spits blood, lower blood, hematuria, under married woman's uterine bleeding band, month time is uncomfortable, tire all kinds of diseases and ailments in front postpartum.
Mulberries are sweet; Acid; Cold in nature, return through liver; Kidney channel, effect: nourishing yin and supplementing blood; Promote the production of body fluid and moisturize. Cure mainly: what kidney deficiency and liver and deficiency of blood essence were lost has a dizzy spell; Soreness of waist tinnitus; Poliosis; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; The dry constipation of intestines. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": kidney-nourishing is dirty and controlling nocturnal emission with astringent drugs takes black invention order for a long time. 5. " detailed outline ": smash juice drink, separate alcohol intoxication, wine brewing clothes, sharp aqueous vapor, detumescence.
Eclipta grass is the conventional liver-nourishing kidney-boosting of the traditional Chinese medical science, cooling blood and hemostasis medicine. To due to all diseases of Light-headedness, tooth mobility, aching pain in waist and back, flaccidity and weakness of the lower limbs due to the deficiency of liver-yin and kidney-yin and blood-head multiple go out blood trouble have good efficacy. Eclipta prostrata contains the chemical compositions such as volatile oil, tannin, saponin, Eclipta prostrata element and vitamin A. Animal experiment has haemostatic effect, and in vitro test has inhibitory action to staphylococcus aureus.
The dried rhizome of rehmannia: the dried rhizome of rehmannia is also radix rehmanniae recen, the fresh or dry piece root of Scrophulariaceae herbaceos perennial glutinous rehmannia RehmanniaglutinosaLibosch.. Heat-clearing, promote the production of body fluid, moisturize, laxation, the broken stasis of blood, raw new, pain relieving, menstruation regulating, the metal-inflicted wound stasis of blood, cool blood, hemostasis; The effect of fresh rehmannia root and radix rehmanniae recen is different. Fresh rehmannia root clearing heat and promoting fluid, can stop blooding and cool blood, is often for consumption of YIN caused by febrile disease, the illnesss such as haematemesis, abscess of throat, the deep red polydipsia of tongue, a spot dermexanthesis and nosebleed heat. With respect to fresh rehmannia root, radix rehmanniae recen is heat clearing and blood cooling, also can promote the production of body fluid, and all right yin-nourishing is used for treating yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, the deep red polydipsia of tongue, sends out the problems such as spot dermexanthesis. The dried rhizome of rehmannia is cold in nature, and function is enriching yin and nourishing kidney. Not only promote the production of body fluid to quench thirst and heat clearing and blood cooling, also have effect, every blood system to have the people of thermal burn the moon to metrorrhagia, irregular menstruation, fetal irritability, constipation etc., can often take. If want to treat warm heat disease, can do qingying decoction with the dried rhizome of rehmannia; If the later stage for the treatment of warm disease, because waste heat does not also disappear to the greatest extent, should be used for boiling Qinghao Biejia Tang the dried rhizome of rehmannia; In addition, contain for blood-head poison, macula purple is black, and the serious heat of warm heat disease enters the symptom of ying blood, can take the Sisheng Wan that the dried rhizome of rehmannia is made; The general nourishing Yin and promoting production of body fluid of wanting treats that interior heat quenches one's thirst with constipation, should eat the once liquid soup that the dried rhizome of rehmannia boils.
Peach kernel hardship, sweet, put down the special medicine closing for blood stasis blood. Bitter to let out stagnant blood, the new blood of Gan Yisheng. " medicine justice ": peach kernel, bitter can rush down blood-head, and it is dry that body profit can be grown intestines. If it is multiplex that gross weight grinds, walk Liver Channel, the main broken blood that holds, water month by month, and pain all over, four limbs wood numbness, left hemiplegia, left sufficient patient, relaxes through the promoting circulation of blood of invigorating blood circulation with it, there is the merit of eliminate blood stasis and promote tissue regeneration, if few use is mashed in peeling, enter large intestine, controlling blood depletion just closes, blood is dry just difficult, with its make moist cool blood and blood, has out the logical stagnant power of knot.
Radix Angelicae Sinensis: its taste is sweet and weigh, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting circulation of blood, and bowl spares has, in row, has benefit, the really gas medicine in blood, the also panacea in blood. Approximately mending to mend of assistant, thus can support nutrition blood, tonifying Qi production of sperm, five viscera settling, strong body, beneficial mind, all tangible deficient diseases, unsuitable without institute. Assistant logical to attack, thus the pain defaecation of dispelling, relieving rigidity of muscles and joints, control contraction,Paralysis, the card such as dry, puckery. Seek void and exterior syndrome being not relieved person, help with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can fall apart greatly, and table is not held back person, and assistant, with rheum officinale and so on, can be shown again admittedly. Precisely because gas Xin Erdong, thus want its quiet person when keeping away it, the sliding benefaction of property, stool is not consolidated person when keeping away it. All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.
The root bark of tree peony, has another name called moutan bark, Chinese medicine name. For the dry root skin of ranunculaceae peony. Originate in the ground such as Anhui, Shandong. Excavate root autumn, remove radicula, strip root skin, dry. Raw using or stir-fry use. Compendium of Material Medica: " nourishing Yin and falling fire, separate spot poison, throat, diuresis stasis. Descendant specially controls fire mutually with yellow tiller, does not know that the merit of the root bark of tree peony more wins also. Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it. " modern study, contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action; The methanolic extract of moutan bark has inhibition Platelet; Paeonol has the effects such as the central inhibitory actions such as calmness, cooling, antipyretic, analgesia, spasmolysis and antiatherosclerosis, diuresis, antiulcer.
RADIX POLYGONI MULTIFLORI PREPARATA: the Chinese medicine fleece-flower root have Radix Polygoni Multiflori and RADIX POLYGONI MULTIFLORI PREPARATA point, direct slicing is used as medicine for Radix Polygoni Multiflori, mixes after steaming and dries and be used as medicine for RADIX POLYGONI MULTIFLORI PREPARATA with black soya bean liquor. The function of the two is different: the removing toxic substances of Radix Polygoni Multiflori function, the carbuncle that disappears, relax bowel, be usually used in treating scrofula sore carbuncle, rubella itch, the dry constipation of intestines; The filling liver kidney of RADIX POLYGONI MULTIFLORI PREPARATA function, benefiting essence-blood, black beard and hair, strengthening the bones and muscles, under sallow, the dizzy tinnitus of the deficiency of blood, poliosis, soreness and weakness of waist and knees, extremity numbness, uterine bleeding band, chronic malaria body void etc. RADIX POLYGONI MULTIFLORI PREPARATA of the present invention is the good merchantable brand of invigrating kidney.
Reticulate millettia bitter but slightly sweet taste, warm in nature, returns liver, the heart, kidney channel; Look red enter blood, matter profit row is loose; Have and activate blood and relax tendons, effect of nourishing blood for regulating menstruation; Cure mainly arthralgia due to wind-dampness, numb in every limb, limbsParalysis, irregular menstruation, blockage of menstruation, dysmenorrhoea, through closing, leukopenia. Waist gonalgia, arthralgia due to wind-dampness, the extremity numbness for the treatment of due to rheumatism, the compatibilities such as normal and safflower peach kernel, the banksia rose, earthworm, the Radix Astragali, Radix Angelicae Sinensis, the red sage root. Can be used for irregular menstruation, through closing, dysmenorrhoea, normal with rhizoma cyperi, motherwort with use.
Motherwort taste is arduous, cool. Invigorate blood circulation, dispel silt, menstruation regulating, water disappears. Treatment menoxenia, threatened abortion difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, the carbuncle sore that swells. Motherwort is containing materials such as leonurines, fumaric acid, has the effects such as promoting blood circulation for regulating menstruation, hypotensive, inducing diuresis to reduce edema.
Flos Albiziae contains silk tree glucoside, tannin, and resolving stagnation for tranquilization, the appetizing of regulating the flow of vital energy, activating collaterals to relieve pain, for confused and worried, melancholy insomnia. Control pent-up uncomfortable in chest, insomnia, forgetful, acute conjunctivitis, can five viscera settling, and will, happy color, have preferably keep fit, calm, the effect of calming the nerves, improve looks, be also to treat neurasthenic good merchantable brand. Also there is clearing away summerheat, face-beautifying and spot-removing effect such as relieve the effect of alcohol. " book on Chinese herbal medicine warp " said: " Flos Albiziae energy five viscera settling, and will, happy color. " especially to pregnant woman, have preferably keep fit, calm, the effect of calming the nerves, improve looks, be also to treat neurasthenic good merchantable brand.
Sophora flower, the traditional Chinese medical science is thought its bitter, cold nature, returns liver, large intestine channel; Enter blood and hold back and fall, body is slightly loose; There is cooling blood and hemostasis, effect of clearing liver-fire; Cure mainly hematochezia, hemorrhoid blood, bloody flux, hematuria, blood drenches, and uterine bleeding is spitted blood, bleeding from five sense organs or subcutaneous tissue, irascibility headache, red eye, swell pain, larynx numbness, aphonia, ulcer sores. And from the angle of doctor trained in Western medicine, sophora flower containing the materials such as rutin (being rutin sophorin, Rytub), Quercetin (Quercetin), tannin, sophoradiol (sophoradiol), vitamin A (specifically can referring to below containing scale). Rutin can be improved the function of capillary, keeps capillary normal resistance, prevent because of capillary fragility excessive, hemorrhage, hypertension, diabetes that permeability is too high to be caused, can preventing of clothes is hemorrhage. So the many common medicines as having blood in stool for treatment of sophora flower, the hemorrhoid hemorrhage causing for large intestinal damp-heat, have blood in stool, haematemesis, bleeding from five sense organs or subcutaneous tissue that bloody flux and blood-head cause. Be generally decoction, 10~15g, suitable amount used externally, deficiency-cold in spleen and stomach and fever due to yin deficiency and without the careful clothes of excess fire person [
The radix paeoniae rubrathe is cool in nature, and bitter acid, is slightly cold, and has the soft liver of enriching blood, flat liver pain relieving. Astringe yin is received the effects such as sweat, is applicable to fever due to yin deficiency, irregular menstruation, chest abdomen pain over the hypochondriac region, four limbs contraction suddenly, rushes down dysentery stomachache, spontaneous sweating, uterine bleeding, is with inferior disease. That Paeoniflorin has is antibacterial, antipyretic, anti-inflammatory, increase coronary flow, improve myocardial nutritional flow, hemangiectasis, antagonism acute myocardial ischemia, suppress the effect of platelet aggregation, calmness, analgesia, spasmolysis, antiulcer, adjusting blood sugar. Root of herbaceous peony decoction can suppress shigella dysenteriae, streptococcus pneumonia, Escherichia coli, typhoid bacillus, hemolytic streptococcus, Pseudomonas aeruginosa etc. The deficiency of blood deficiency of Yin, chest abdomen pain over the hypochondriac region, pain in the hepatic region, cholecystitis, gall stone pain, to rush down the illness patients such as dysentery stomachache, women's menalgia, the easy sweat night sweat of spontaneous perspiration, systremma, spasm of limbs pain, uneasy leg syndrome suitable edible.
Cape jasmine is traditional Chinese medicine, belongs to the 1st batch of medicine-food two-purpose resource that the Ministry of Public Health promulgates, has the effects such as the liver of protecting, cholagogic, step-down, calmness, hemostasis, detumescence, is usually used in treating the diseases such as icteric hepatitis, bruise, hypertension, diabetes at tcm clinical practice. Cure mainly pyreticosis vexed; Irascibility hot eyes; Headache; Jaundice with damp-heat pathogen; Stranguria; Bloody flux hematuria; Aphthae; Sore swollen toxin; Sprain and swell and ache. This product has very large curative effect to red eye, swell pain. These product rush down clearly three warmers heat evil, can control the red eye, swell pain that liver and gall are attacked on burning hot, often join rheum officinale use, as cape jasmine soup " General Records of Holy Universal Relief ".
Centella Latin formal name used at school Centellaasiatica (L.) Urban, has clearing heat and detoxicating, inducing diuresis and reducing edema, nourishing, anti-inflammatory, quelling effect. Can stimulate deep skin cell to substitute. Centella can compact epidermis and corium coupling part, can make skin limber up, and contributes to solve cutis laxa phenomenon, makes skin smooth flexible; Promote that collagen forms in skin corium, make fibrin regeneration, reconnect, skin is reached compact smooth effect. Also can help impaired organization healing and consolidation skin. Can promote close connection the between epidermis and corium, can suppress again the increase of adipocyte, prevent hydroderma, occur obesity.
Purslane (Latin formal name used at school: PortulacaoleraceaL.) is Portulacaceae annual herb plant. Plump succulence, without hair, high 10~30cm, is born in the area without shade such as roadside, field and ruins, flower garden. All there is distribution domestic various places. This kind is medicine food dual purpose plant. Herb hyoscine, has clearing heat and promoting diuresis, removing toxicity for detumescence, anti-inflammatory, quenches the thirst, diuresis; Seed improving eyesight. Modern study, purslane also contains abundant SL3 aliphatic acid and vitamin A sample material. SL3 aliphatic acid is to form cell membrane, especially brain cell membrane and the necessary material of eye cell membrane; Vitamin A sample substance maintains epithelial tissue as skin, cornea and conjunctival normal function, participates in the synthetic of visual purple, strengthens retina photosensitive property, also participates in many oxidizing process in body.
Sun plant (formal name used at school: ScutellariabarbataD.Don) all herbal medicine, has clearing heat and detoxicating, promoting blood circulation, swelling and pain relieving, the function such as anticancer. Taste acid cold in nature, herb is containing compositions such as multivitamin, trace element and amino acid. There is removing pattogenic heat from the blood and toxic material from the body, blood stasis removing analgesic, effect of detumescence and clearing heat and promoting diuresis. Function cures mainly: have clearing heat and detoxicating, promoting blood circulation and removing blood stasis, swelling and pain relieving, anticancer effect; Appendicitis curing, hepatitis, stomachache, early liver cancer, lung cancer, cervix cancer, mastitis etc.; External application is controlled pain furuncle and is treated, the diseases such as treating swelling and pain by traumatic injury. This medicine large usage quantity among the people. " Guangxi medicine is plantedFigureWill ": anti-inflammatory, loose stasis of blood hemostasis. Control to fall and injure and bloody flux. " Nanning City's medicine will ": swelling and pain relieving. Control that falling forges a knife injures sore. " Quanzhou book on Chinese herbal medicine ": dredging collateral, clearing heat and detoxicating, the loose blood that dispels the wind, promoting qi circulation to induce diuresis, broken stasis of blood pain relieving. Main blood for oral administration drenches, spits blood, and bleeding from five sense organs or subcutaneous tissue; Venomous snake bite is controlled in external application, ulcer, furunculosis, nameless sores or boils.
Trollflower, another name: the cold lotus of non-irrigated lotus, common nasturtium herb; Formal name used at school: TrolliuschinensisBunge is the plant of Ranunculaceae Trollius. Annual or perennial herb. Tool medicinal function, can be clearing heat and detoxicating, cures mainly tonsillitis, tympanitis. For acute and chronic tonsillitis, otitis media acuta, acute myringitis, acute conjunctivitis, acute lymphangitis. " detailed outline is picked up any lost article from the road ": control aphtha, larynx is swollen, superficial heat pingival atrophy, ear pain, order pain, improving eyesight, separates haze miasma. " Hebei Chinese medicine handbook ": clearing heat and detoxicating, flower is used as medicine, and controls chronic tonsillitis, share with chrysanthemum and Radix Glycyrrhizae, can control the disease such as otitis media acuta, acute conjunctivitis (Hebei Chinese medicine handbook).
Pot marigold (Calendulaofficinalis) has another name called pot marigold, and ancient western is made medicinal or dyestuff, also makes cosmetics or edible, and leaf and petal edible are made the decoration of dish. Originate in southern Europe. There is medical value antiphlogistic antibacterial heat-clearing and fire-reducing, control whelk, acne. Pot marigold is rich in multivitamin, especially vitamin A and vitamin C; Almost each position can eat; Its petal has the function of beauty treatment, and flower is containing carotenoid, lycopene, violaxanthin, rubixanthin, volatile oil, resin, lymphatic temperament, malic acid etc. Root contains amaroid, mountain gold east glycol; Seed is containing glyceride, ceryl alcohol and alkaloid. Putting in shampoo to make hair color thin out. Flower, leaf has anti-inflammatory, antibacterial action, particularly better to staphylococcus, streptococcus effect. Its antimicrobial component is dissolved in alcohol and is water insoluble. [1], in alkaline environment, effect is better. Animal experiment proves, flower extract has sedation to central nervous system, reduces reflex excitability; Intravenous injection can cause Blood pressure drop, strengthens cardiomotility, increases heartbeat amplitude, reducing heart rate, the choleresis of promotion dog, accelerated wound healing. The Europe outer various inflammation for skin, mucous membrane among the people, also oral administration is controlled various inflammation and ulcer (as gastric and duodenal ulcer, gastritis, hepatobiliary disease etc.). Can alleviate poisoning symptom, improve appetite, sleep etc. for Alimentary Tract Cancer, also be useful on irregular menstruation person. Tincture has killing action to virus in test tube, but the viral pneumonia that mouse is produced with A2Frunzefluvirus does not show result for the treatment of. The water extract of leaf has the effect (prothrombin time shortening) of accelerating blood clotting, but this is relevant with wherein contained tannin and calcium salt. Root: the promoting flow of qi and blood circulation. Flower: cool blood, hemostasis.
Raspberry, Chinese medicine name. For the dry fruit of rosaceous plant rubus chingii Hu RubuschingiiHu. There is supplementing the kidney to control the nocturnal contracting urine, the effect nourishing the liver to improve visual acuity. Be usually used in emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, order is secretly dim-sighted. " explaining abstruseness of the canon of materia medica ": " raspberry, sweet putting down into kidney are played a sun and are controlled impotence, and controlling nocturnal emission with astringent drugs is taken the photograph excessive, strong kidney and without scorching inclined to one side, and controlling nocturnal emission with astringent drugs and puckery undoubtedly evil, the product of gold and jade are also. " " book on Chinese herbal medicine justice ": " raspberry is for nourishing Kidney-Yin medicine, and the micro-acid of taste band can be received and be taken the photograph the cloudy gas of dissipation and production of sperm liquid, therefore Kou Zongshi is called kidney-nourishing and dwindled just, its excessive device is covered in working as of clothes, though language is drawn wrong conclusions by false analogy, is still reasonable.
The specific embodiment of the invention
Specific embodiment 1:
When 6-8 selfheal in middle of the month fruit ear is brownish red, gather, remove impurity, dry, raw use, Jiang Qipao enters alcohol extract or extraction.
Again by all the other raw material ecliptas, centella, peach kernel, the radix paeoniae rubrathe, sophora flower, trollflower, raspberry, the dried rhizome of rehmannia, the root bark of tree peony, cape jasmine, motherwort, pot marigold, RADIX POLYGONI MULTIFLORI PREPARATA, Flos Albiziae, reticulate millettia, Sculellaria barbata, purslane, pulverizes, extraction or extract and make extract.
Two kinds of extracts mix, ultraviolet radiation for sterilizing and disinfecting bottling.
Specific embodiment 2:
When being brownish red, 6-8 selfheal in middle of the month fruit ear gathers, remove impurity, dry, raw using, general 5000g, after impurity elimination chopping, steeped in the ethanol that 5-10 doubly measures, medicinal powder is equipped with and is covered in stainless steel cask, added 70% ethanol, quality is 0.8-1 times of meal, stir, moistening airtight placement more than 1 hour, makes abundant expansion; After percolator bottom filter plate is paved with gauze bag parcel, again the drug sample after moistening expansion is mixed to pine and done loose, then contain powder with stainless steel spoon, pack uniformly percolator into, dress 10-12 cm thick, press evenly with T-shaped rod, then press aforesaid operations, packing in layer, suitably pressurization, medicinal powder must not load and exceeded 2/3 eminence of percolator; Medicinal powder face upper cover stainless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, then slowly adds 70% ethanol; Air between medicinal powder powder to be discharged, and there is ethanol to flow out about 20L left and right, close baiting valve, cover the cylinder of filtering, dipping 24 hours, then open baiting valve and carry out diacolation, control diacolation speed and be generally 1000g medicinal material outflow 2~3ml per minute, filtrate is put into liquid container, and ethanol when emptying is poured liquid container into; Percolate is merged and left standstill.
Get again other raw material eclipta 1500g, centella 1500g, peach kernel 1500g, radix paeoniae rubrathe 1500g, sophora flower 1500g, trollflower 1500g, raspberry 1500g, dried rhizome of rehmannia 1500g, root bark of tree peony 1500g, cape jasmine 1500g, motherwort 1500g, pot marigold 1500g, RADIX POLYGONI MULTIFLORI PREPARATA 1500g, Flos Albiziae 1500g, reticulate millettia 1500g, Sculellaria barbata 1500g, purslane 1500g, cleans and dries, in 70 DEG C of baking ovens, dry 8-12h, take out and be placed in drying box coolingly, pulverized 80-100 mesh sieve with pulverizer; The particle that sieves is soaked in water 12 hours, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and heating, boils 45 minutes for the second time, filters, and filtrate is for subsequent use; Filter residue adds water again, and heating is for the third time boiled half an hour, filters, and heating is concentrated into paste, stand for standby use. Paste extract is placed in to 70-90% ethanol and soaks 1-2 hour, in water-bath, be heated to 60 DEG C-70 DEG C, lixiviate 2h, every 10min stirs once, by filtered through gauze, in residue, add 50-60% ethanol, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, be condensed into pasty state filtrate
Above-mentioned two kinds of extracts are mixed and inserted in economic benefits and social benefits vacuum concentrator, the concentrate that while being concentrated into 90 DEG C, relative density is 1.05, set to 0~5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g crude drug amount, ultraviolet disinfection, packaging bottling.
Specific embodiment 3:
When 6-8 selfheal in middle of the month fruit ear is brownish red, gather, remove impurity, dry, raw use, general 4500g. Pulverized 80-100 mesh sieve with pulverizer; The particle that sieves is soaked in water 12 hours, then put into extractor heating and boil 1 hour, filter, filtrate is for subsequent use; Filter residue adds water, and heating, boils 45 minutes for the second time, filters, and filtrate is for subsequent use; Filter residue adds water again, and heating is for the third time boiled half an hour, filters, and heating is concentrated into paste, stand for standby use. Paste extract is placed in to 70-90% ethanol and soaks 1-2 hour, in water-bath, be heated to 60 DEG C-70 DEG C, lixiviate 2h, every 10min stirs once, by filtered through gauze, in residue, add 50-60% ethanol, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, be condensed into pasty state filtrate, stand-by.
Get again other raw material eclipta 1200g, centella 1100g, peach kernel 1100g, radix paeoniae rubrathe 1100g, sophora flower 1200g, trollflower 1100g, raspberry 1100g, dried rhizome of rehmannia 1100g, root bark of tree peony 1100g, cape jasmine 1100g, motherwort 1100g, pot marigold 1100g, RADIX POLYGONI MULTIFLORI PREPARATA 1100g, Flos Albiziae 1100g, reticulate millettia 1100g, Sculellaria barbata 1100g, purslane 1100g, get other raw materials and clean impurity elimination, steep in the ethanol that 5-10 doubly measures, medicinal powder is equipped with and is covered in stainless steel cask, add 70% ethanol, quality is 0.8-1 times of meal, stir, moistening airtight placement is more than 1 hour, make abundant expansion, after percolator bottom filter plate is paved with gauze bag parcel, again the drug sample after moistening expansion is mixed to pine and done loose, then contain powder with stainless steel spoon, pack uniformly percolator into, dress 10-12 cm thick, press evenly with T-shaped rod, then press aforesaid operations, packing in layer, suitably pressurization, medicinal powder must not load and exceeded 2/3 eminence of percolator, medicinal powder face upper cover stainless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, then slowly adds 70% ethanol, air between medicinal powder powder to be discharged, and there is ethanol to flow out about 20L left and right, close baiting valve, cover the cylinder of filtering, dipping 24 hours, then open baiting valve and carry out diacolation, control diacolation speed and be generally 1000g medicinal material outflow 2~3ml per minute, filtrate is put into liquid container, and ethanol when emptying is poured liquid container into, percolate is merged and left standstill.
Insert in economic benefits and social benefits vacuum concentrator the concentrate that while being concentrated into 90 DEG C, relative density is 1.05, set to 0~5 DEG C of deepfreezes 24 hours for two kinds that above-mentioned steps is obtained; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g crude drug amount; Then add dextrin, after ultraviolet sterilization, bottle.
Pharmacology toxicity test
Experimental example 1: acute toxicity test of the present invention
One, test material: animal: Kunming mouse, body weight 18-25g, male and female half and half, Shandong University's biology laboratory breeding. Medicine: the present invention's (all raw material mixes decoction 2 times, merges and filters, taking liquid) is containing 0.0365mg/ml.
Two, method:
1, LD50 calculates: adopt improvement karber's method, mouse is divided into 5 groups at random, 10 every group, male and female half and half, dissolve adding distil water of the present invention, are made into Cmax, by the administration of the maximum permission capacity of mouse, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml, observes animal dead situation.
2, maximum tolerated dose is measured (MTD value): get 20 of mouse, each 10 of male and female. Adding distil water of the present invention is dissolved, be made into maximum concentration, by the maximal tolerance dose of animal, fill with hello device and can twitch and be as the criterion to inject. In animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml (every ml is containing crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption. Continuous Observation 7 days after administration.
Three, result of the test:
LD50 calculate in the time giving mouse with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, do not measure LD50, ask only maximum tolerated dose, in 7 day observation period, its appetite of animal, activity, hair color, the state of mind etc. are all normal, grow normally, there are no death. Select 300 times of doses that are equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD > 18g/Kg.d.
Experimental example 2: the result of the test of acute toxicity and long term toxicity
Acute toxicity test: give the present invention by the disposable gavage of small white mouse, maximum concentration 35%, maximum gavage capacity 0.4ml/10g, dosage 14g/kg (every g medicinal powder is equivalent to 0.1g crude drug), Continuous Observation 7 days, do not find any toxic reaction, because concentration and dosage cannot increase, therefore fail to measure the LD50 of this medicine. Maximum tolerance determination: with maximum concentration, maximum gavage capacity, mice lavage administration 3 times, 5 hours, interval, then Continuous Observation 7 days, none example is dead. Medicinal powder dosage is > 42g/kg. day (every g medicinal powder is equivalent to 0.1g crude drug), calculate the clinical consumption per day that is equivalent to be grown up by kg body weight 420 times.
Long term toxicity test: whether produce toxic reaction for observing long-term prescription, give respectively rat the present invention and raise clothes, by adult 70 times of clinical consumption per day and 35 times (being 7g/kg/ day and 3.5g/kg/ day), to give and feed 8 weeks continuously, the behavior, feed, the body weight that have no rat occur extremely, with control group ratio, routine blood test, hepatic and renal function, various important organs are all without abnormal change, within the scope of institute's dosage, do not find any toxicity of the present invention. By the acute and chronic toxicity test confirmation of animal, safe range of the present invention is larger, is a kind of safe and reliable health products.
Pharmacological experiment:
1 material
1.1 animals: 60 of healthy 3 monthly age pure lines Kunming kind female mices, body weight 25~35g, the animal used as test department of the Chinese Academy of Sciences of University Of Qingdao provides. Animal feeding condition: every group of mouse is by group sub-cage rearing. In the situation that natural conditions are identical, routine is raised food drinking-water, keeps natural lighting, and without undesirable element impact, raise and within 1 week, adapt to start to test after experimental situation,
1.2 experimental drugs: toxin-expelling and face nourishing health care oral liquid of the present invention, by selfheal, eclipta, centella, peach kernel, the radix paeoniae rubrathe, sophora flower, trollflower, raspberry, the dried rhizome of rehmannia, the root bark of tree peony, cape jasmine, motherwort, pot marigold, RADIX POLYGONI MULTIFLORI PREPARATA, Flos Albiziae, reticulate millettia, Sculellaria barbata, purslane, pulverizes, press the method preparation of embodiment 2, concentration: 0.1g/ml, Pharmacy of the court produces. Drugs compared: commercially available toxin-discharging nourishing capsule, interwined dragon sea of clouds medicine company.
1.3 reagent: vulcanized sodium (NaS): the limited public affairs of extra large Ling Feng chemical reagent can, lot number: 20020118, be made into before use 10% aqueous solution. Superoxide dismutase (SOD), MDA (MDA) kit: Bioengineering Research Institute is built up in Nanjing, lot number: 20059116.
1.4 key instruments: DY89-II type electric driven glass refiner: Xin Lan biotech inc, Ningbo. System biological microscope: OLYMPUS; BX50F4 Beijing Institute of Aeronautics pathological image analytical system.
2 experimental techniques
2.1 modellings: with reference to chloasma experimental animal model clone method. After mouse 2.5% yellow Jackets anesthesia, press the intramuscular injection of 0.02g/kg dosage mouse hind leg, 6 times weekly, continuous 4 weeks with 0.4% progesterone injection. Normal group is pressed 0.02g/kg intramuscular injection sterilized water for injection.
2.2 animal grouping and administrations: get 60 of Healthy female mouse, 3 dosage groups, are divided into 6 groups at random, 10 every group. Normal group, model group, 3 dosage groups of spot-removing beautifying face oral liquid of the present invention (0.15,0.3,0.6g/g), 3% quinhydrones positive controls (0.6g/g). 3 dosage treatment groups of spot-removing beautifying face oral liquid of the present invention are respectively in mouse modeling medication on the same day, every day 1 time, 6 times weekly, continuous use 30 days. Normal group and model group give distilled water in the corresponding time; 3% quinhydrones positive drug control group started local application in modeling the same day, and time and the course for the treatment of are with spot-removing beautifying face oral liquid treatment group.
2.3 observation index and detection: medication is after 30 days, and mouse, back unhairing are put to death in cervical vertebra dislocation, get rapidly each 2 of the skin histology at hepatic tissue and coating position, wherein remove blood with ice-cold normal saline flushing for one, filter paper blots, cut the each 0.5g of liver and skin, the beaker of putting into respectively the pre-cold saline of 2.0ml, shreds tissue, then pours in test tube, with high speed disperser 10r/min homogenate twice, each 10 seconds; With 3500r/min rotating speed centrifugal 15 minutes again, get supernatant. Adopt xanthine oxidase, detect description method by kit and measure SOD; Adopt thiobarbituricacidα-method, detect description method by kit and measure MDA value. Meanwhile, separating mouse skin of back, gets one of plucked skin histology (2cm*1cm left and right), and 10% paraformaldehyde is fixed, routine paraffin wax embedding, section, HE dyeing, conventional organization pathological examination, om observation, counting epithelial proliferation, corium blood vessel number and chorionitis cell number; Immunohistochemical staining, and the dyeing of observation melanocyte and number (positive cell: nothing, count 0 point; < 15%, counts 0.5 point, and < 30% counts 1 point; 30% 2 points of >).
2.4 statistical methods: relatively t inspection between measurement data employing group; Layering calculating chart adopts rank test to carry out statistical disposition.
3 results
The mensuration of 3.1 each group mouse skins, hepatic tissue MDA, SOD content is shown inTable 1
Table 1The mensuration of each group mouse skin and hepatic tissue MDA, SOD content (x ± s)
With relatively * P < 0.05 of model group, * * P < 0.01; With relatively #**P < 0.05 of positive group
It is visible that 3.2 each group mouse skin Pathomorphologics and immunohistochemistry are observed PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM: the epithelial layer cell arrangement of normal group mouse skin is neat, without hyperplasia, has no little blood vessel dilatation in skin corium, and inflammatory cell is rare. The epithelial layer hyperplasia of model group mouse skin is obvious, the large and arrangement disorder of core, and visible little blood vessel dilatation in skin corium, inflammatory cell is common. The epithelial layer hyperplasia of dosage group big or middle and positive controls mouse skin alleviates to some extent, and arrangement disorder alleviates, and in skin corium, little blood vessel dilatation alleviates, and inflammatory cell is rare. The results are shown inTable 2
Immunohistochemical PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM is visible: visible a little melanocyte in normal group mouse epithelial layer, the painted sepia of endochylema. Visible a large amount of melanocytes in model group mouse epithelial layer, the painted dark brown of endochylema, and positive cell number > 30%. Visible black color element cell in dosage group big or middle and positive controls mouse epithelial layer, the painted dark brown of endochylema, positive cell number reduces, and seesTable 2
Table 2 each group mouse skin histopathology morphology and melanocyte observed result (n)
Rank test; With relatively * P < 0.05 of model group, * * P < 0.01
4 discuss
The chloasma traditional Chinese medical science is called " chloasma hepaticum ", belongs to motherland's medical science " dark spot " or " dusty complexion " category. It is generally acknowledged that this disease occurs with liver,spleen,kidney three dirty in close relations.
It is exactly taking blood as use that woman maintains the first step, because the physilogical characteristics such as women's menstruation, tire are pregnant, delivery and feed infant and lactation are all easily consumed blood, so the relatively easy state in blood system deficiency of women's body. Say as " a Ling Shu Miraculous Pivot or Divine Axis five flavours and five notes of traditional Chinese music section ": " women's life, has a surplus in gas, is not enough to blood, counts collapse due to massive hemorrhage also with it. So ", first female health preserving should pay attention to maintaining qi and blood. That hemapodium just can make to have rosy cheeks is beautiful, menses normal, spirit is vigorous. Nourish blood if be bad at, just easily occur that sallow complexion is simple and unadorned, lip and nail are pale, dizzy, lassitude hypodynamia, send out withered limb fiber crops,, menstrual period delay few through blood volume, the light arteries and veins of tongue are thin etc. When serious anaemia, also easily occur wrinkle early raw, grey hair early white, climacteric the early ageing situation such as in advance. Human body is " flesh and blood ". Only have qi and blood foot, just seem that skin is ruddy, face is glossy; Only have meat real, just can have muscular, build fitness. For women, pursue face gorgeous, stature is gentle and graceful, should focus on benefiting qi and nourishing blood.
Along with social development, increasing and the lack of standardization use of cosmetics, the pollution of atmospheric environment, the chloasma incidence of disease rises year by year, cosmetics lead, mercury, hormone severe overweight, use these type of cosmetics to be as good as " drinking poison to quench thirst ", Chinese traditional treatment chloasma origin stream is long, by the conditioning of oral liquid of the present invention, makes drug and nutriment matter in the situation that skin temperature raises, accelerate infiltration and absorb, thereby reach perfect result for the treatment of.
How to get through human detoxification pipeline, by toxin expelling main pipeline---alimentary canal is discharged vivotoxin, and by the combination of logical benefit, the exquisite prescription compatibility of medicines such as lifting is proper, with the conditioning metabolism of human disorder and the endocrine of imbalance, regulate fuselage state balance, make function activity normal, qi and blood smoothness, mechanism of qi bar reaches, equilibrium between yin and yang, qi and activate blood circulation, catharsis and toxin expelling, thus reach the dual purpose of toxin expelling and beauty treatment. From the angle of body structure, toxin expelling is the adjustment to whole toxin expelling system, comprises the conditioning to human-body viscera function, the dredging of the toxin expelling pipelines such as blood vessel, lymphatic vessel, tracheae, the urinary tract, digester tube, the adjusting to QI-blood circulation etc. The present invention row, the system of separating, adjusting, mending quaternity, scientifically application is the combination of traditional Chinese medical science science, method, prescription, drugs. Selfheal, fruit, leaf and Gen Ke are used as medicine, and generally make tea or decoct soup clothes. Cape jasmine is containing gardenoside, geniposide, Chinese Fevervine Herb time glucoside methyl esters and a small amount of shanzhiside, has that reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body, jaundice, blood drench that pain is puckery, the red and swollen pain of order, fiery carbuncle, the effect such as hypotensive. From the angle of body structure, toxin expelling is the adjustment to whole toxin expelling system, comprises the conditioning to human-body viscera function, the dredging of the toxin expelling pipelines such as blood vessel, lymphatic vessel, tracheae, the urinary tract, digester tube, the adjusting to QI-blood circulation etc.
The present invention, by toxin expelling main pipeline blood, discharges vivotoxin, and by the combination of logical benefit, the exquisite prescription compatibility of medicines such as lifting is proper, with the conditioning metabolism of human disorder and the endocrine of imbalance, regulate fuselage state balance, make function activity normal, qi and blood smoothness, mechanism of qi bar reaches, equilibrium between yin and yang, qi and activate blood circulation, catharsis and toxin expelling, thus reach the dual purpose of toxin expelling and beauty treatment.

Claims (10)

1. a selfheal health care oral liquid for cool blood toxin expelling, is characterized in that, described health care oral liquidComprise the bulk drug of following parts by weight: 10~50 parts of selfheals, 10~20 parts of ecliptas, centella 10~20 parts, 10~20 parts, peach kernel, 10~20 parts of the radix paeoniae rubrathe, 10~20 parts, sophora flower, 10~20 parts of trollflowers, cover10~20 parts, basin, 10~20 parts, the dried rhizome of rehmannia, 10~20 parts of the root barks of tree peony, 10~20 parts of cape jasmines, motherwort 10~20 parts, 10~20 parts of pot marigolds, 10~20 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 10~20 parts of Flos Albiziaes, reticulate millettia 10~20Part, 10~20 parts of Sculellaria barbatas, 10~20 parts of purslanes.
2. the selfheal health care oral liquid of cool blood toxin expelling according to claim 1, is characterized in that instituteState the bulk drug that health care oral liquid comprises following parts by weight: 10~30 parts of selfheals, eclipta 10~15Part, 10~15 parts of centellas, 10~15 parts, peach kernel, 10~15 parts of the radix paeoniae rubrathe, 10~15 parts, sophora flower, lily feetSpend 10~15 parts, 10~15 parts of raspberries, 10~15 parts, the dried rhizome of rehmannia, 10~15 parts of the root barks of tree peony, cape jasmine 10~20Part, 10~20 parts of motherworts, 10~20 parts of pot marigolds, 10~20 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 10~20 parts of Flos Albiziaes,10~20 parts of reticulate millettias, 10~20 parts of Sculellaria barbatas, 10~20 parts of purslanes.
3. the selfheal health care oral liquid of cool blood toxin expelling according to claim 1, is characterized in that instituteState the bulk drug that health care oral liquid comprises following parts by weight: 10~40 parts of selfheals, eclipta 10~20Part, 10~20 parts of centellas, 10~20 parts, peach kernel, 10~20 parts of the radix paeoniae rubrathe, 10~20 parts, sophora flower, lily feetSpend 10~20 parts, 10~20 parts of raspberries, 10~20 parts, the dried rhizome of rehmannia, 10~20 parts of the root barks of tree peony, cape jasmine 10~15Part, 10~20 parts of motherworts, 10~20 parts of pot marigolds, 10~20 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 10~20 parts of Flos Albiziaes,10~20 parts of reticulate millettias, 10~20 parts of Sculellaria barbatas, 10~20 parts of purslanes.
4. the selfheal health care oral liquid of a cool blood toxin expelling as described in any one in claim 1~3Preparation method, is characterized in that, the preparation process of described selfheal health care oral liquid comprises following aspect:
A. gather when selfheal fruit ear is brownish red when summer, remove impurity, dry, raw using;
B. the selfheal of drying being pulverized, soaked ethanol heating extracts;
C. alcohol extract is pulverized, soaked to described other raw materials;
D. other raw material extracts are mixed with the selfheal extract preparing and concentrate, sterilizing is prepared into mouthTake liquor.
5. the preparation method of the selfheal health care oral liquid of cool blood toxin expelling according to claim 4, its spyLevy and be, in described step a, between the 6-8 month, in the time that selfheal fruit ear is brownish red, harvesting, airing,Allow it parch, for subsequent use.
6. the preparation method of the selfheal health care oral liquid of cool blood toxin expelling according to claim 4, its spyLevy and be, in described step b, selfheal chopping is placed in 70-90% ethanol and soaks 1-2 hour,In water-bath, be heated to 60 DEG C-70 DEG C, lixiviate 2h, every 10min stirs once, by filtered through gauze, in residue, addsEnter 50-60% ethanol, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, and filtered through gauze mergesLeaching liquor, is condensed into pasty state filtrate, stand-by.
7. the preparation method of the selfheal health care oral liquid of cool blood toxin expelling according to claim 4, its spyLevy and be, in described step c, all the other raw materials are cleaned to impurity elimination, put into 10 times of amount ethanol, soak 1-2Hour, heating is extracted 2 times, and each 1-2 hour, removes supernatant, merges extract, and 100-120 order filters,Be the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams again, ultrafiltrate reduced pressure concentration relative density is 80DEG C time 1.05 filtrate.
8. the preparation method of the selfheal health care oral liquid of cool blood toxin expelling according to claim 4, its spyLevy and be, in described steps d, two kinds of extracts are inserted in economic benefits and social benefits vacuum concentrator, be concentrated into 90 DEG CTime the relative density concentrate that is 1.25, set to 0~5 DEG C of deepfreezes 24 hours; Refrigeration liquid is added to 0.3%Filter aid diatomite, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1gCrude drug amount is bottled after ultraviolet ray sterilization bactericidal.
9. the selfheal health care oral liquid of a cool blood toxin expelling as described in any one in claim 1~3Preparation method, is characterized in that, the preparation process of described selfheal health care oral liquid comprises following aspect:
A. gather when selfheal fruit ear is brownish red when summer, remove impurity, dry, raw using;
B. the selfheal of drying is pulverized, soaked ethanol and add extraction heat;
C. alcohol extract is pulverized, soaked to described other raw materials;
D. other raw material extracts are mixed with the selfheal extract preparing and concentrate, sterilizing is prepared into mouthTake liquor.
10. the preparation method of the selfheal health care oral liquid of cool blood toxin expelling according to claim 9, itsBe characterised in that, in described step b, the extraction step of selfheal is: get selfheal chopping for subsequent use, bubbleEnter in the ethanol that 5-10 doubly measures, medicinal powder is equipped with and is covered in stainless steel cask, add 70% ethanol, quality is thickThe 0.8-1 of powder doubly, stirs, and moistening airtight placement more than 1 hour, makes abundant expansion; By percolatorBottom filter plate is mixed the drug sample after moistening expansion pine after paving with gauze bag parcel again and is done loose, then usesStainless steel spoon is contained powder, packs uniformly percolator into, and dress 10-12 cm thick is even by T-shaped rod pressure, then by upperState operation, packing in layer, suitably pressurization, medicinal powder must not load and exceeded 2/3 eminence of percolator;Medicinal powder face upper cover stainless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, thenSlowly add 70% ethanol; Air between medicinal powder powder to be discharged, and have ethanol to flow out an about 20L left sideThe right side, closes baiting valve, covers the cylinder of filtering, dipping 24 hours, then opens baiting valve and carries out diacolation, and control is oozedThe speed of filtering is generally 1000g medicinal material outflow 2~3ml per minute, and filtrate is put into liquid container, and by emptyingTime ethanol pour liquid container into; Percolate is merged and left standstill.
CN201510753514.9A 2015-11-09 2015-11-09 Prunella vulgaris health-care oral liquid for cooling blood and clearing away toxic materials and preparation method thereof Withdrawn CN105582151A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049429A (en) * 2006-04-03 2007-10-10 北京因科瑞斯生物制品研究所 Tablet for regulating menstruation and removing speckles of department of gynecology, and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049429A (en) * 2006-04-03 2007-10-10 北京因科瑞斯生物制品研究所 Tablet for regulating menstruation and removing speckles of department of gynecology, and preparation method

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