CN105579849A - 在用于检测多聚靶分子的基于颗粒的测试中防止聚集的试剂、方法和设备 - Google Patents
在用于检测多聚靶分子的基于颗粒的测试中防止聚集的试剂、方法和设备 Download PDFInfo
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- CN105579849A CN105579849A CN201480044234.4A CN201480044234A CN105579849A CN 105579849 A CN105579849 A CN 105579849A CN 201480044234 A CN201480044234 A CN 201480044234A CN 105579849 A CN105579849 A CN 105579849A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
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- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
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- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Description
Claims (15)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13170722.6 | 2013-06-06 | ||
EP13170722 | 2013-06-06 | ||
PCT/IB2014/061986 WO2014195899A1 (en) | 2013-06-06 | 2014-06-05 | Reagents, methods and devices to prevent aggregation in particle based tests for the detection of multimeric target molecules |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105579849A true CN105579849A (zh) | 2016-05-11 |
CN105579849B CN105579849B (zh) | 2019-02-22 |
Family
ID=48576294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201480044234.4A Active CN105579849B (zh) | 2013-06-06 | 2014-06-05 | 在用于检测多聚靶分子的基于颗粒的测试中防止聚集的试剂、方法和设备 |
Country Status (5)
Country | Link |
---|---|
US (1) | US10895571B2 (zh) |
EP (1) | EP3004882B1 (zh) |
JP (2) | JP2016520846A (zh) |
CN (1) | CN105579849B (zh) |
WO (1) | WO2014195899A1 (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109416357A (zh) * | 2016-06-30 | 2019-03-01 | 皇家飞利浦有限公司 | 用于检测包含多个细胞的体液样本中的分析物的设备、***和方法 |
CN109863400A (zh) * | 2016-10-24 | 2019-06-07 | 豪夫迈·罗氏有限公司 | 固定化分析物 |
WO2020191602A1 (zh) * | 2019-03-25 | 2020-10-01 | 京东方科技集团股份有限公司 | 一种免疫检测芯片、免疫检测装置及使用方法 |
CN113302492A (zh) * | 2019-01-03 | 2021-08-24 | 彼克斯赛尔医疗科技有限公司 | 用于分析流体样品的***和方法 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3234601B1 (en) * | 2014-12-18 | 2019-10-09 | Roche Diagnostics GmbH | Methods for reducing interferences |
US20210063387A1 (en) * | 2017-08-26 | 2021-03-04 | Aj Innuscreen Gmbh | Means and method for detecting analytes by means of macroscopic granulate particles |
Citations (3)
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CN1646913A (zh) * | 2002-04-10 | 2005-07-27 | 反应生物医学公司 | 敏感性免疫色原图像测试 |
CN101438163A (zh) * | 2006-05-09 | 2009-05-20 | 皇家飞利浦电子股份有限公司 | 利用磁场检测样品中的靶分子 |
WO2013072877A1 (en) * | 2011-11-16 | 2013-05-23 | Koninklijke Philips Electronics N.V. | Particle repulsion to enhance surface contact in magnetic particle immunoassays |
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US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
GB9107030D0 (en) * | 1991-04-04 | 1991-05-22 | Wellcome Found | Assay |
EP1169646A2 (en) * | 1999-01-25 | 2002-01-09 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
US20010049111A1 (en) * | 1999-08-13 | 2001-12-06 | Norbert Windhab | Methods, procedures, and formats for using microelectronic array devices to perform multiplex immunoassay analyses |
US6680209B1 (en) * | 1999-12-06 | 2004-01-20 | Biosite, Incorporated | Human antibodies as diagnostic reagents |
EP3241838A1 (en) * | 2006-02-08 | 2017-11-08 | Becton Dickinson and Company | Sers nanotag assays |
US20080138842A1 (en) * | 2006-12-11 | 2008-06-12 | Hans Boehringer | Indirect lateral flow sandwich assay |
JP2010512534A (ja) | 2006-12-12 | 2010-04-22 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | ラベル粒子を検出するマイクロエレクトロニクスセンサデバイス |
WO2008083323A1 (en) * | 2006-12-29 | 2008-07-10 | Invitrogen Corporation | Detection apparatus |
US8227201B2 (en) | 2007-06-27 | 2012-07-24 | Board Of Trustees Of The Leland Stanford Junior University | BETA2-microglobulin and C reactive protein (CRP) as biomarkers for peripheral artery disease |
CN102149753B (zh) * | 2008-09-11 | 2013-09-25 | 国立大学法人东京工业大学 | 含有荧光分子的聚合物颗粒及其制造方法 |
WO2010109392A1 (en) * | 2009-03-23 | 2010-09-30 | Koninklijke Philips Electronics N.V. | Manipulation of magnetic particles in a biological sample |
EP2720060A1 (en) | 2009-09-28 | 2014-04-16 | Koninklijke Philips N.V. | A biosensor system for single particle detection |
JP5814806B2 (ja) * | 2011-03-30 | 2015-11-17 | 株式会社東芝 | 光導波路型測定システム、測定方法及び光導波路型センサチップ |
US8982136B2 (en) * | 2011-05-16 | 2015-03-17 | Qualcomm Incorporated | Rendering mode selection in graphics processing units |
EP2594942A1 (en) | 2011-11-16 | 2013-05-22 | Koninklijke Philips Electronics N.V. | Long rigid spacers to enhance binding kinetics in immunoassays |
-
2014
- 2014-06-05 CN CN201480044234.4A patent/CN105579849B/zh active Active
- 2014-06-05 WO PCT/IB2014/061986 patent/WO2014195899A1/en active Application Filing
- 2014-06-05 EP EP14732973.4A patent/EP3004882B1/en active Active
- 2014-06-05 US US14/896,182 patent/US10895571B2/en active Active
- 2014-06-05 JP JP2016517724A patent/JP2016520846A/ja active Pending
-
2018
- 2018-10-19 JP JP2018197798A patent/JP6746866B2/ja active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1646913A (zh) * | 2002-04-10 | 2005-07-27 | 反应生物医学公司 | 敏感性免疫色原图像测试 |
CN101438163A (zh) * | 2006-05-09 | 2009-05-20 | 皇家飞利浦电子股份有限公司 | 利用磁场检测样品中的靶分子 |
WO2013072877A1 (en) * | 2011-11-16 | 2013-05-23 | Koninklijke Philips Electronics N.V. | Particle repulsion to enhance surface contact in magnetic particle immunoassays |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109416357A (zh) * | 2016-06-30 | 2019-03-01 | 皇家飞利浦有限公司 | 用于检测包含多个细胞的体液样本中的分析物的设备、***和方法 |
CN109416357B (zh) * | 2016-06-30 | 2022-07-15 | 西门子医疗***荷兰有限公司 | 用于检测包含多个细胞的体液样本中的分析物的设备、***和方法 |
CN109863400A (zh) * | 2016-10-24 | 2019-06-07 | 豪夫迈·罗氏有限公司 | 固定化分析物 |
CN109863400B (zh) * | 2016-10-24 | 2022-06-24 | 豪夫迈·罗氏有限公司 | 固定化分析物 |
US11585811B2 (en) | 2016-10-24 | 2023-02-21 | Roche Diagnostics Operations, Inc. | Immobilized analytes |
CN113302492A (zh) * | 2019-01-03 | 2021-08-24 | 彼克斯赛尔医疗科技有限公司 | 用于分析流体样品的***和方法 |
WO2020191602A1 (zh) * | 2019-03-25 | 2020-10-01 | 京东方科技集团股份有限公司 | 一种免疫检测芯片、免疫检测装置及使用方法 |
US12000828B2 (en) | 2019-03-25 | 2024-06-04 | Boe Technology Group Co., Ltd. | Immunodetection chip, immunodetection device and using method |
Also Published As
Publication number | Publication date |
---|---|
EP3004882A1 (en) | 2016-04-13 |
US20160123965A1 (en) | 2016-05-05 |
EP3004882B1 (en) | 2018-03-21 |
WO2014195899A1 (en) | 2014-12-11 |
US10895571B2 (en) | 2021-01-19 |
CN105579849B (zh) | 2019-02-22 |
JP2019060873A (ja) | 2019-04-18 |
JP2016520846A (ja) | 2016-07-14 |
JP6746866B2 (ja) | 2020-08-26 |
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Effective date of registration: 20180726 Address after: Ian Deho Finn AE5656 hi tech park, Holland 29 Applicant after: Micro Care Pte. Ltd. Address before: Holland Ian Deho Finn Applicant before: KONINKLIJKE PHILIPS N.V. |
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Address after: Holland Hague Patentee after: Siemens Medical Systems Holland Ltd. Address before: Holland Hague Patentee before: Siemens Medical diagnostic solutions first Holdings Ltd. |
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Effective date of registration: 20210122 Address after: Holland Hague Patentee after: Siemens Medical diagnostic solutions first Holdings Ltd. Address before: Holland Hague Patentee before: Siemens Medical Holland Ltd. Effective date of registration: 20210122 Address after: Holland Hague Patentee after: Siemens Medical Holland Ltd. Address before: Ian Deho Finn AE5656 hi tech park, Holland 29 Patentee before: Micro Care Pte. Ltd. |
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