CN105566168A - Creatine mother liquid separation purification processing system - Google Patents
Creatine mother liquid separation purification processing system Download PDFInfo
- Publication number
- CN105566168A CN105566168A CN201510993440.6A CN201510993440A CN105566168A CN 105566168 A CN105566168 A CN 105566168A CN 201510993440 A CN201510993440 A CN 201510993440A CN 105566168 A CN105566168 A CN 105566168A
- Authority
- CN
- China
- Prior art keywords
- creatine
- mother liquor
- electrodialyzer
- tank
- treatment system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01D—COMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, POTASSIUM, RUBIDIUM, CAESIUM, OR FRANCIUM
- C01D3/00—Halides of sodium, potassium or alkali metals in general
- C01D3/04—Chlorides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2006/00—Physical properties of inorganic compounds
- C01P2006/80—Compositional purity
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
Abstract
The present invention discloses a creatine mother liquor separation purification processing system including a mother liquor tank for containing mother liquor after creatine synthesis, the mother liquor tank is connected with a liquid conveying tube, a first liquid feed pump is in series connection with the liquid conveying tube, the mother liquor is pumped into an electrodialyzer by the first liquid feed pump for purification separation, an electrodialysis membrane is installed in the electrodialyzer, and a creatine solution tank and a salt-containing solution tank are in series connection after the electrodialyzer, and respectively contain a creatine solution and a salt-containing solution after processing of the mother liquor by the electrodialyzer. The creatine mother liquor separation purification processing system is capable of achieving safe, economical and environmentally friendly separation purification of the creatine mother liquor.
Description
Technical field
The present invention relates to separation technology field, particularly relate to a kind of creatine mother liquor isolation of purified treatment system.
Background technology
Creatine (Creatine) is white powder crystallization, odorless, mildly bitter flavor, and molecular formula is C
4h
9n
3o
2, molecular weight (MolecularWeight) is 131.13, water-soluble, is slightly soluble in cold water, is insoluble to dehydrated alcohol, ether and acetone.
Creatine is a kind of amino acid derivative, is the natural nutrient be present in human body, and in human body, creatine synthesizes in liver, kidney, pancreas.Creatine, to the synthesis promoting nucleic acid, protein, increases the deposit of energy i (in vivo) material, promotes the growth of muscle, and delay fatigue and acceleration physical efficiency recovery have important effect.
At present, all give enough attention to the production of this product and application both at home and abroad, report document is also more, and the route that foreign literature mentions synthesis creatine mainly contains following several:
1) calcyanide and sodium sarcosinate reactant aqueous solution directly generate creatine;
2) calcyanide reacts to obtain O-methyl-isourea hydrochloride with the dry satisfied methanol solution of hydrogen chloride gas, and O-methyl-isourea hydrochloride is obtained by reacting creatine with sarkosine again;
3) calcyanide and aqueous hydrochloric acid generate chloro carbonamidine muriate under the condition passing into air, are then obtained by reacting creatine with sodium sarcosinate;
4) Mono Chloro Acetic Acid and methylamine are obtained by reacting sodium sarcosinate or sarkosine potassium, then are obtained by reacting creatine with cyanamide;
5) with thiocarbamide and methyl-sulfate for raw material generates S-methyl-isourea, S-methyl-isourea again with sarkosine, sodium sarcosinate or sarkosine nak response to creatine.
6) urea and methyl-sulfate are obtained by reacting O-methyl-isourea methyl sulfate, need not be further purified, then be obtained by reacting creatine with sodium sarcosinate.
By comparing, which kind of method don't work, the existence of sodium salt and sylvite all can be had in the mother liquor of synthesis creatine, because environmental protection pond requires that the salt of water inlet is lower, mother liquor not directly discharges, and mother liquor contains creatine and a large amount of salt, by while recycling mother liquor improve effects, the pressure to environmental protection can be reduced.Existingly carry out desalination purification mother liquor by ion-exchange resin and concentrated method, but these method cost compares are large, can produce secondary pollution to environment.
Summary of the invention
The technical problem that the present invention mainly solves is to provide a kind of creatine mother liquor isolation of purified treatment system, can safety, economy, environmental protection the isolation of purified realizing creatine mother liquor.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is:
A kind of creatine mother liquor isolation of purified treatment system is provided, comprise the mother liquor tank of the mother liquor after splendid attire synthesis creatine, described mother liquor tank is connected with liquid pushing tube, described liquid pushing tube is in series with the first liquid feeding pump, mother liquor pumps in electrodialyzer and carries out purification separation by described first liquid feeding pump, is provided with electrodialytic membranes in described electrodialyzer; Creatine solution tank and saline solns tank is in series with, respectively the creatine solution of mother liquor described in splendid attire after described electrodialyzer process and saline solns after described electrodialyzer.
In a preferred embodiment of the present invention, described saline solns also then again pumps in electrodialyzer via the second liquid feeding pump containing certain density creatine afterwards after testing and carries out purification separation again.
In a preferred embodiment of the present invention, the inorganic salt in described saline solns are sodium-chlor.
In a preferred embodiment of the present invention, the temperature of described mother liquor is 10 ~ 50 DEG C.
In a preferred embodiment of the present invention, in described mother liquor, the massfraction of creatine is 0.01 ~ 5%, and the massfraction of described inorganic salt is 0.1 ~ 25%.
The invention has the beneficial effects as follows: creatine mother liquor isolation of purified treatment system of the present invention, remaining creatine in mother liquor after synthesis creatine thoroughly can be separated with inorganic salt and reclaim, and do not produce " three wastes " in whole production process, native system structure is simple, processing ease, adds economic benefit.
Accompanying drawing explanation
Fig. 1 is the structural representation of a preferred embodiment of the present invention;
In accompanying drawing, the mark of each parts is as follows: 1, electrodialyzer, and 11, electrodialytic membranes, 2, mother liquor tank, the 3, first liquid feeding pump, 4, liquid pushing tube, 5, creatine solution tank, 6, saline solns tank, the 7, second liquid feeding pump.
Embodiment
Below in conjunction with accompanying drawing, preferred embodiment of the present invention is described in detail, can be easier to make advantages and features of the invention be readily appreciated by one skilled in the art, thus more explicit defining is made to protection scope of the present invention.
A kind of creatine mother liquor isolation of purified treatment system, comprise the mother liquor tank 2 of the mother liquor after splendid attire synthesis creatine, described mother liquor tank 2 is connected with liquid pushing tube 4, described liquid pushing tube 4 is in series with the first liquid feeding pump 3, mother liquor pumps in electrodialyzer 1 and carries out purification separation by described first liquid feeding pump 3, is provided with electrodialytic membranes 11 in described electrodialyzer 1; Creatine solution tank 5 and saline solns tank 6 is in series with, respectively the creatine solution of mother liquor described in splendid attire after described electrodialyzer 1 processes and saline solns after described electrodialyzer 1.
Described saline solns also then again pumps in electrodialyzer 1 via the second liquid feeding pump 7 containing certain density creatine afterwards after testing and carries out purification separation again.
Inorganic salt in described saline solns are sodium-chlor.
The temperature of described mother liquor is 10 ~ 50 DEG C, and in described mother liquor, the massfraction of creatine is 0.01 ~ 5%, and the massfraction of described inorganic salt is 0.1 ~ 25%.
Embodiment 1: the 500g creatine mother liquor containing massfraction being 0.8% creatine and 25% sodium-chlor is contained in mother liquor tank 2, at 20 DEG C of temperature, utilize the first liquid feeding pump 3 by liquid pushing tube 4, deliver in the electrodialyzer 1 of in-built electrodialytic membranes, because electrodialytic membranes is different with the electric conductivity of inorganic salt to creatine, different by property, thus can thoroughly be separated creatine and inorganic salt, appropriate water synergy is added in electrodialyzer 1, final process obtains 479g massfraction to be 24.5% sodium chloride aqueous solution and 98g massfraction be 0.14% the creatine aqueous solution, sodium chloride aqueous solution is deposited in saline solns tank 6, the creatine aqueous solution is present in creatine solution tank 5.
Embodiment 2: the 500g creatine mother liquor containing massfraction being 2% creatine and 5% sodium-chlor is left in mother liquor tank 2, at 20 DEG C of temperature, utilize the first liquid feeding pump 3 by liquid pushing tube 4, deliver in the electrodialyzer 1 of in-built electrodialytic membranes, add appropriate water, final process obtain 491g massfraction be 4.5% sodium chloride aqueous solution and 94g massfraction be 0.48% the creatine aqueous solution, sodium chloride aqueous solution is deposited in saline solns tank 6, and the creatine aqueous solution is present in creatine solution tank 5.After to detect in sodium chloride aqueous solution also containing a small amount of creatine, therefore again the sodium chloride aqueous solution containing creatine is pumped in electrodialyzer 1 by the second liquid feeding pump 7, with creatine mother liquor again together with carry out isolation of purified.
The foregoing is only embodiments of the invention; not thereby the scope of the claims of the present invention is limited; every utilize specification sheets of the present invention and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.
Claims (5)
1. a creatine mother liquor isolation of purified treatment system, it is characterized in that, comprise the mother liquor tank of the mother liquor after splendid attire synthesis creatine, described mother liquor tank is connected with liquid pushing tube, described liquid pushing tube is in series with the first liquid feeding pump, mother liquor pumps in electrodialyzer and carries out purification separation by described first liquid feeding pump, is provided with electrodialytic membranes in described electrodialyzer; Creatine solution tank and saline solns tank is in series with, respectively the creatine solution of mother liquor described in splendid attire after described electrodialyzer process and saline solns after described electrodialyzer.
2. creatine mother liquor isolation of purified treatment system according to claim 1, is characterized in that, described saline solns also then again pumps in electrodialyzer via the second liquid feeding pump containing certain density creatine afterwards after testing and carries out purification separation again.
3. creatine mother liquor isolation of purified treatment system according to claim 1, it is characterized in that, the inorganic salt in described saline solns are sodium-chlor.
4. creatine mother liquor isolation of purified treatment system according to claim 1, is characterized in that, the temperature of described mother liquor is 10 ~ 50 DEG C.
5. creatine mother liquor isolation of purified treatment system according to claim 1, it is characterized in that, in described mother liquor, the massfraction of creatine is 0.01 ~ 5%, and the massfraction of described inorganic salt is 0.1 ~ 25%.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510993440.6A CN105566168A (en) | 2015-12-28 | 2015-12-28 | Creatine mother liquid separation purification processing system |
| PCT/CN2016/110940 WO2017114224A1 (en) | 2015-12-28 | 2016-12-20 | Creatine mother liquid separation and purification processing system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510993440.6A CN105566168A (en) | 2015-12-28 | 2015-12-28 | Creatine mother liquid separation purification processing system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105566168A true CN105566168A (en) | 2016-05-11 |
Family
ID=55876874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510993440.6A Pending CN105566168A (en) | 2015-12-28 | 2015-12-28 | Creatine mother liquid separation purification processing system |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN105566168A (en) |
| WO (1) | WO2017114224A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017114224A1 (en) * | 2015-12-28 | 2017-07-06 | 江苏远洋药业股份有限公司 | Creatine mother liquid separation and purification processing system |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988002652A1 (en) * | 1986-10-14 | 1988-04-21 | Allied Corporation | Recovery of acids from materials comprising acid and salt |
| CN201470316U (en) * | 2009-08-12 | 2010-05-19 | 浙江玉泉环境工程有限公司 | Electrodialysis membrane method desalting device |
| CN101966426A (en) * | 2010-09-15 | 2011-02-09 | 中国科学院过程工程研究所 | Electric dialyzator for desalting fermentation liquor |
| CN104176844A (en) * | 2014-05-14 | 2014-12-03 | 重庆紫光化工股份有限公司 | Recycling system and recycling method for waste liquor produced in separation and purification of organically synthesized feed liquid |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105566168A (en) * | 2015-12-28 | 2016-05-11 | 江苏远洋药业股份有限公司 | Creatine mother liquid separation purification processing system |
-
2015
- 2015-12-28 CN CN201510993440.6A patent/CN105566168A/en active Pending
-
2016
- 2016-12-20 WO PCT/CN2016/110940 patent/WO2017114224A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988002652A1 (en) * | 1986-10-14 | 1988-04-21 | Allied Corporation | Recovery of acids from materials comprising acid and salt |
| CN201470316U (en) * | 2009-08-12 | 2010-05-19 | 浙江玉泉环境工程有限公司 | Electrodialysis membrane method desalting device |
| CN101966426A (en) * | 2010-09-15 | 2011-02-09 | 中国科学院过程工程研究所 | Electric dialyzator for desalting fermentation liquor |
| CN104176844A (en) * | 2014-05-14 | 2014-12-03 | 重庆紫光化工股份有限公司 | Recycling system and recycling method for waste liquor produced in separation and purification of organically synthesized feed liquid |
Non-Patent Citations (1)
| Title |
|---|
| 周军等: "电渗析技术在工业废水处理中应用的研究", 《节能与环保》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017114224A1 (en) * | 2015-12-28 | 2017-07-06 | 江苏远洋药业股份有限公司 | Creatine mother liquid separation and purification processing system |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017114224A1 (en) | 2017-07-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103382170A (en) | Preparation method for taurine | |
| CN105084587A (en) | Treatment method and equipment of high-salt waste water | |
| PH12015500642A1 (en) | Process and system for producing sodium chloride brine | |
| CN102838497B (en) | Cleaning production process of glycine | |
| NZ721694A (en) | A sea water harvesting process | |
| CN105764880A (en) | Waste treatment process comprising treating waste stream with base at elevated temperature | |
| CN108675511A (en) | A kind of preparation method of deep-sea mineralized liquid | |
| PT104149A (en) | PROCESS OF CO-PRODUCTION OF CHITINE, ITS DERIVATIVES AND POLYMERS CONTAINING GLUCOSE, MANOSE AND / OR GALACTOSE, BY CULTURE OF YEAST PICHIA PASTORIS | |
| CN106957883A (en) | A kind of allicin synthesizes the process of 4,5,9-trithiadodeca-1,6,11-triene 9-oxide | |
| CN105646291A (en) | Method for separating and purifying creatine mother liquor | |
| CN103012609A (en) | Method for extracting fucosan sulphate from sea cucumber cooking waste liquor | |
| CN105566168A (en) | Creatine mother liquid separation purification processing system | |
| CN104059002A (en) | Ultrasonic assisted aqueous two-phase extraction method for alliin | |
| CN104370396A (en) | Zero-emission treatment method and device for desalinating strong brine by using seawater | |
| CN104387504A (en) | Method for preparing heparin sodium by using small intestines of pigs | |
| CN103951572A (en) | Separation and purification process for producing branched chain amino acid by using fermentation method | |
| CN102659650A (en) | Device and method for preparing DL-methionine salt | |
| CN204265576U (en) | A kind of sea water desalinization strong brine zero discharge treatment device | |
| CN103274954A (en) | Production process of Gly | |
| CN105851478B (en) | production method for preparing feed by using waste liquid from amino acid production | |
| CN219898110U (en) | Creatine production system | |
| CN105418462A (en) | Synthetic method of creatine | |
| CN103467324B (en) | Preparation method of N, N-dimethylglycine for industrial production | |
| CN209836047U (en) | Phytic acid dechlorination system | |
| CN207619433U (en) | A kind of xylose retracting device of xylose acid hydrolysis solution |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160511 |
|
| RJ01 | Rejection of invention patent application after publication |