CN105557773A - Nuclear magnetic resonance equipment disinfectant and preparation method thereof - Google Patents
Nuclear magnetic resonance equipment disinfectant and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a nuclear magnetic resonance equipment disinfectant. The disinfectant is mainly prepared from, by mass, 0.8-1.6 parts of mixed cresol, 1-3 parts of chlorhexidine gluconate, 2-4 parts of sodium dichloro isocyanurate, 4-6 parts of sodium lauryl ether sulfate, 50-60 parts of deionized water, 6-10 parts of semen arecae, 4-9 parts of melia toosendan, 9-17 parts of chaulmoogratree seeds, 12-18 parts of fructus forsythiae, 8-14 parts of philippine violet herb, 4-9 parts of herba houttuyniae, 10-14 parts of radix pulsatillae and 5-10 parts of pipewort. The prepared product is stable in performance, low in toxicity, good in sterilizing and disinfecting effect, rapid in sterilizing, free of corrosion to metal and friendly to the environment.
Description
Technical field
The present invention relates to thimerosal field, particularly relate to a kind of NMR disinfectant and method for making.
Background technology
The current medical disinfectant of China mainly contain chlorohexidene, salicylate, ethanol, isopropyl alcohol, formalin, chloroform etc., be mainly used for killing pathogenic microorganism on communication media, it is made to reach innoxious requirement, pathogenic microorganism is eliminated outside human body, cut off the route of transmission of infectious disease, reach the object controlling infectious disease.For different dissipation demand in hospital, be divided into directed toward bacteria, fungi and spore class, General Requirements has the bactericidal effect of wide spectrum, and applicability widely.The current medical disinfectant consumption of China is 10,000,000,000,000 tons, and capacity is surprising.But sterilization used at present often only for single bacterium or one-component, is difficult to have spectrum effects.Or for the apparatus that some have higher requirements, be often difficult to reach requirement.
Publication No. CN104839247A(application number 201510235415.1) Chinese patent literature disclose a kind of Medical antiseptic solution, raw material has Schisandra sphenanthera Rehd.et WilS 4-8 part, paris polyphylla 9-14 part, cogongrass rhizome 4-12 part, metronidazole 3-6 part, lauric acid diethyl amide 3-4 part, Norfloxacin 3-5 part, sodium sulfosuccinate 5-9 part, sorbitan sesquioleate 4-6 part, glycine 3-8 part, root of Chinese clematis 5-7 part, peroxidase 7-9 part, carboxymethyl cellulose 5-8 part, aralia decaisneana Hance 7-14 part, red chopsticks 6-12 part, yellowflower toadlily herb 8-13 part.Publication No. CN103493853A(application number 201310443136.5) Chinese patent literature disclose a kind of thimerosal, it is obtained by the raw material of following weight percentage: mix containing following parts by weight ingredient in the thimerosal of its 100 weight portion: the extract of 60-70 part compound Chinese medicinal material, chlorhexidine acetate 1.5-2.5, ethanol 60-70, water surplus; In described compound Chinese medicinal material, each raw material weight ratio is: natural bo-chrysanthemum 20-25, peppermint 10-15, david poplar root-bark 10-15, anemone vitifolia 10-15, folium isatidis 15-20, Paris polyphylla 15-20, honeysuckle 10-15, pine needle 15-20, root bark of shaggy-fruited dittany 10-15, root of large-flowered skullcap 7-12, smilax 15-20, frutus cnidii 15-20, eggplant winter root 7-12, hairyvein agrimony 5-10, cotton rose 5-10.Publication No. CN103548906A(application number 201310453814.6) Chinese patent literature disclose a kind of sterilizing liquid composite, be made up of the raw material of following parts by weight: garlic juice 10-25 part, TUQILIANG 2-7 part, nutgall 3-6 part, chenopodium ambrosiodies 4-8 part, Balsamiferou Blumea Herb 5-8 part, honeysuckle 4-7 part, clorox 3-8 part, terpineol 3-6 part, polyvinylpyrrolidone 4-8 part, kuh-seng 4-8 part, coptis 5-7 part, golden cypress 3-6 part, tuber of stemona 4-8 part, castor oil 2-8 part, pure water 30-40 part.
A kind of thimerosal of Long-Time Service, bacterium and fungi can produce certain tolerance to it, thus affect Disinfection Effect, and then are difficult to cut off transmission of disease, bring very large difficulty to clinical treatment and effective spreading of infection control.And general disinfectants can make the medical devices such as operating theater instruments produce variable color and bring bad smell etc., is not suitable for Long-Time Service.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of with low cost, prepare simple NMR disinfectant and method for making.
Technical scheme of the present invention is:
NMR disinfectant, is prepared from primarily of following raw materials according, is mass parts: 3 mixed cresol 0.8-1.6, chlorhexidine gluconate 1-3, sodium dichloro cyanurate 2-4, sodium lauryl tri(oxyethyl) sulfate 4-6, deionized water 50-60, betel nut 6-10, Fructus meliae toosendan 4-9, chaulmoogra 9-17, capsule of weeping forsythia 12-18, Chinese violet 8-14, cordate houttuynia 4-9, Chinese pulsatilla 10-14, pipewort 5-10.
In preferred scheme, 3 mixed cresol 1.0-1.4, chlorhexidine gluconate 1.5-2.5, sodium dichloro cyanurate 2.5-3.5, sodium lauryl tri(oxyethyl) sulfate 4.5-5.5, deionized water 52-58, betel nut 7-9, Fructus meliae toosendan 5-8, chaulmoogra 11-15, capsule of weeping forsythia 14-16, Chinese violet 10-12, cordate houttuynia 5-8, Chinese pulsatilla 11-13, pipewort 6-9.
Be more preferably, 3 mixed cresol 1.2, chlorhexidine gluconate 2, sodium dichloro cyanurate 3, sodium lauryl tri(oxyethyl) sulfate 5, deionized water 55, betel nut 8, Fructus meliae toosendan 6.5, chaulmoogra 13, the capsule of weeping forsythia 15, Chinese violet 11, cordate houttuynia 6.5, the Chinese pulsatilla 12, pipewort 7.5.
The preparation method of described NMR disinfectant, step is:
(1) cleaned by betel nut and break into pieces, boil with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, and gets wheat bran and is placed in frying pan and has been heated to cigarette and emerges, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran be buff, sieve and remove wheat bran, pulverize raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 40-60 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) Chinese pulsatilla cleans section, ginger juice and brown sugar poach 15-20 minute (preferred, to boil 17 minutes), then adds Chinese violet and mix thoroughly, and Guan Huo, adds a cover vexed, takes out, dries;
(4) decocted by adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material, big fire is boiled and to be filtered after 25-35 minute that (preferred, 27-33 minute is boiled in big fire; Be more preferably, big fire boils 30 minutes), the distilled water that filter residue adds equivalent boils again, filters, merges twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverizes, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
The preparation method of described NMR disinfectant, step (1) mature vinegar boils 17-25 minute, and (preferred, mature vinegar boils 19-23 minute; Be more preferably, mature vinegar boils 21 minutes).
The preparation method of described NMR disinfectant, step (2) is heated to 45-55 DEG C (preferred, to be heated to 50 DEG C).
The preparation method of described NMR disinfectant, step (3) is added a cover and (preferably, is added a cover vexed 14-16 minute in vexed 12-18 minute; Be more preferably, add a cover vexed 15 minutes).
The preparation method of described NMR disinfectant, the amount of step (4) distilled water by decoction material quality 5-7 doubly (preferred, the amount of distilled water by 6 times of decoction material quality).
The preparation method of described NMR disinfectant, the distilled water that step (4) filter residue adds equivalent boil again 20-30 minute (preferred, then boil 22-28 minute; Be more preferably, then boil 25 minutes).
The preparation method of described NMR disinfectant, step (4) was pulverized 180-260 mesh sieve and (preferably, was pulverized 200-240 mesh sieve; Be more preferably, pulverized 220 mesh sieves).
NMR disinfectant preparation science provided by the invention, with low cost, in addition, excellent results of the present invention also shows: products made thereby stable performance of the present invention, and toxicity is low, and disinfection effect is good, sterilization is rapid, and corrosion-free to metal, environmentally friendly.
Embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
Embodiment 1 NMR disinfectant, is prepared from (every part of 500g) primarily of following raw materials according: 3 mixed cresol 0.8 part, chlorhexidine gluconate 1 part, sodium dichloro cyanurate 2 parts, sodium lauryl tri(oxyethyl) sulfate 4 parts, deionized water 50 parts, betel nut 6 parts, Fructus meliae toosendan 4 parts, chaulmoogra 9 parts, the capsule of weeping forsythia 12 parts, Chinese violet 8 parts, cordate houttuynia 4 parts, the Chinese pulsatilla 10 parts, pipewort 5 parts.
The preparation method of above-mentioned NMR disinfectant is:
(1) break into pieces clean for betel nut, boil 17 minutes with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, get wheat bran to be placed in frying pan and to be heated to cigarette and to emerge, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran is buff, sieve removes wheat bran, pulverizes raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 40 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) get the Chinese pulsatilla and clean section, with ginger juice and poach 15 minutes, then add Chinese violet and mix thoroughly, Guan Huo, adds a cover vexed 12 minutes, takes out, dries;
(4) adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material is decocted, the amount of distilled water by 5 times of decoction material quality, big fire is boiled after 25 minutes and is filtered, and the distilled water that filter residue adds equivalent boils 20 minutes again, filters, merge twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverized 180 mesh sieves, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
Embodiment 2 NMR disinfectant, is prepared from (every part of 500g) primarily of following raw materials according: 3 mixed cresol 1.6 parts, chlorhexidine gluconate 3 parts, sodium dichloro cyanurate 4 parts, sodium lauryl tri(oxyethyl) sulfate 6 parts, deionized water 60 parts, betel nut 10 parts, Fructus meliae toosendan 9 parts, chaulmoogra 17 parts, the capsule of weeping forsythia 18 parts, Chinese violet 14 parts, cordate houttuynia 9 parts, the Chinese pulsatilla 14 parts, pipewort 10 parts.
The preparation method of NMR disinfectant is:
(1) break into pieces clean for betel nut, boil 25 minutes with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, get wheat bran to be placed in frying pan and to be heated to cigarette and to emerge, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran is buff, sieve removes wheat bran, pulverizes raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 60 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) get the Chinese pulsatilla and clean section, with ginger juice and poach 20 minutes, then add Chinese violet and mix thoroughly, Guan Huo, adds a cover vexed 18 minutes, takes out, dries;
(4) adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material is decocted, the amount of distilled water by 7 times of decoction material quality, big fire is boiled after 35 minutes and is filtered, and the distilled water that filter residue adds equivalent boils 30 minutes again, filters, merge twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverized 260 mesh sieves, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
Embodiment 3 NMR disinfectant, is prepared from (every part of 500g) primarily of following raw materials according: 3 mixed cresol 1.0 parts, chlorhexidine gluconate 1.5 parts, sodium dichloro cyanurate 2.5 parts, sodium lauryl tri(oxyethyl) sulfate 4.5 parts, deionized water 52 parts, betel nut 7 parts, Fructus meliae toosendan 5 parts, chaulmoogra 11 parts, the capsule of weeping forsythia 14 parts, Chinese violet 10 parts, cordate houttuynia 5 parts, the Chinese pulsatilla 11 parts, pipewort 6 parts.
The preparation method of NMR disinfectant is:
(1) break into pieces clean for betel nut, boil 19 minutes with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, get wheat bran to be placed in frying pan and to be heated to cigarette and to emerge, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran is buff, sieve removes wheat bran, pulverizes raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 45 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) get the Chinese pulsatilla and clean section, with ginger juice and poach 15 minutes, then add Chinese violet and mix thoroughly, Guan Huo, adds a cover vexed 14 minutes, takes out, dries;
(4) adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material is decocted, the amount of distilled water by 5 times of decoction material quality, big fire is boiled after 27 minutes and is filtered, and the distilled water that filter residue adds equivalent boils 22 minutes again, filters, merge twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverized 200 mesh sieves, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
Embodiment 4 NMR disinfectant, is prepared from (every part of 500g) primarily of following raw materials according: 3 mixed cresol 1.4 parts, chlorhexidine gluconate 2.5 parts, sodium dichloro cyanurate 3.5 parts, sodium lauryl tri(oxyethyl) sulfate 5.5 parts, deionized water 58 parts, betel nut 9 parts, Fructus meliae toosendan 8 parts, chaulmoogra 15 parts, the capsule of weeping forsythia 16 parts, Chinese violet 12 parts, cordate houttuynia 8 parts, the Chinese pulsatilla 13 parts, pipewort 9 parts.
The preparation method of NMR disinfectant is:
(1) break into pieces clean for betel nut, boil 23 minutes with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, get wheat bran to be placed in frying pan and to be heated to cigarette and to emerge, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran is buff, sieve removes wheat bran, pulverizes raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 55 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) get the Chinese pulsatilla and clean section, with ginger juice and poach 20 minutes, then add Chinese violet and mix thoroughly, Guan Huo, adds a cover vexed 16 minutes, takes out, dries;
(4) adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material is decocted, the amount of distilled water by 7 times of decoction material quality, big fire is boiled after 33 minutes and is filtered, and the distilled water that filter residue adds equivalent boils 28 minutes again, filters, merge twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverized 240 mesh sieves, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
Embodiment 5 NMR disinfectant, is prepared from (every part of 500g) primarily of following raw materials according: 3 mixed cresol 1.2 parts, chlorhexidine gluconate 2 parts, sodium dichloro cyanurate 3 parts, sodium lauryl tri(oxyethyl) sulfate 5 parts, deionized water 55 parts, betel nut 8 parts, Fructus meliae toosendan 6.5 parts, chaulmoogra 13 parts, the capsule of weeping forsythia 15 parts, Chinese violet 11 parts, cordate houttuynia 6.5 parts, the Chinese pulsatilla 12 parts, pipewort 7.5 parts.
The preparation method of NMR disinfectant is:
(1) break into pieces clean for betel nut, boil 21 minutes with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, get wheat bran to be placed in frying pan and to be heated to cigarette and to emerge, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran is buff, sieve removes wheat bran, pulverizes raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 50 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) get the Chinese pulsatilla and clean section, with ginger juice and poach 17 minutes, then add Chinese violet and mix thoroughly, Guan Huo, adds a cover vexed 15 minutes, takes out, dries;
(4) adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material is decocted, the amount of distilled water by 6 times of decoction material quality, big fire is boiled after 30 minutes and is filtered, and the distilled water that filter residue adds equivalent boils 25 minutes again, filters, merge twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverized 220 mesh sieves, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
The present invention is raw materials used:
3 mixed cresol: the mixture being orthoresol, metacresol, paracresol three kinds of isomers.3 mixed cresol is a kind of colourless or in yellowish-brown liquid, has phenol smell.As bactericide, preservative, disinfectant, as making smelly liquid medicine, Su Laile (liquid soap of crude cresylic acid), medicine soap etc.About larger than phenol four times of sterilizing power, purchased from Lu Ke chemical industry Co., Ltd of Shouguang City.
Chlorhexidine gluconate: be colourless or faint yellow almost transparent slightly sticky liquid, Cidex-7, has great broad-spectrum antibacterial, bactericidal action, to gram-positive bacteria and Gram-negative bacteria all effective.External application hand, skin degerming, rinse wound, purchased from Lu Ke chemical industry Co., Ltd of Shouguang City.
Sodium dichloro cyanurate: be white powder or granular solid, can the various invasive organism such as powerful kill bacteria gemma, bacterial propagule, fungi, there is special efficacy killing action to hepatitis viruse, kill fast and the powerful algae such as blue-green alge, red algae, marine alga suppressing the systems such as cycle water, cooling tower, pond.Killing action is thoroughly had, purchased from Jinan Xin Wang Chemical Co., Ltd. to the sulfatereducting bacteria, iron bacteria, fungi etc. of circulation.
Sodium lauryl tri(oxyethyl) sulfate: faint yellow paste, excellent decontamination, emulsification and foam performance, do blowing agent and the washing agent of shampoo body lotion, purchased from Wan Zhi chemical inc, Hebei.
Betel nut: base is former: be the seed of babassu betel nut.Nature and flavor: bitter, pungent, temperature.Gui Jing: enter spleen, stomach, large intestine channel.Function cures mainly: desinsection, broken long-pending, lower gas, row water.Control malnutrition due to parasitic infestation, eat stagnant, abdominal distention, rushes down after dysentery heavy, malaria, oedema, beriberi, phlegm addiction, crux.
Fructus meliae toosendan: base is former: be the fruit of canella melia toosendan.Nature and flavor: bitter, cold, poisonous.Gui Jing: enter liver, stomach, small intestinl channel.Function cures mainly: except damp and hot, clearing away the liver-fire, pain relieving, desinsection.Control pyretic epigastralgia, hypochondriac pain, colic, abdominal pain due to enterositosis.
Chaulmoogra: base is former: be the mature seed of Flacourtiaceae plant chaulmoogra.Nature and flavor: pungent, heat, poisonous.Gui Jing: enter liver,spleen,kidney warp.Function cures mainly: dispel pathogenic wind and remove dampness, detoxicating and destroying parasites.Control leprosy, mange, syphilis.
The capsule of weeping forsythia: base is former: be the fruit of the Oleaceae plants capsule of weeping forsythia.Nature and flavor: bitter, cool.Gui Jing: enter the heart, liver, gallbladder channel.Function cures mainly: heat-clearing, removing toxic substances, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.
Chinese violet: base is former: be the herb of Violaceae Chinese violet.Nature and flavor: bitter, acrid, cold.Gui Jing: the thoughts of returning home, Liver Channel.Function cures mainly: clearing heat and detoxicating, cool blood detumescence.For furuncle swelling toxin, ulcer carbuncle on the back, erysipelas, venomous snake bite.
Cordate houttuynia: base is former: be the whole herb with root of saururaceae plant houttuynia cordata.Nature and flavor: pungent, cold.Gui Jing: enter liver, lung two warp.Function cures mainly: clearing heat and detoxicating, inducing diuresis to reduce edema.Control pneumonia, lung abscess, hot dysentery, malaria, oedema, gonorrhoea, leukorrhea, carbuncle swells, hemorrhoid, prolapse of the anus, eczema, the favus of the scalp, mange.
The Chinese pulsatilla: base is former: be the root of the ranunculaceae plant Chinese pulsatilla.Nature and flavor: bitter, cold.Gui Jing: return stomach, large intestine channel.Function cures mainly: clearing heat and detoxicating, removes heat from the blood and relieve diarrhea.For toxic-heat and blood stasis, under pruritus vulvae band, amebic dysentery.
Pipewort: base is former: be the inflorescence of the band scape of Eriocaulaceae plant pipewort.Nature and flavor: pungent, sweet are flat.Gui Jing: return liver, lung channel.Function cures mainly: dispelling wind and heat from the body, and screen is moved back in improving eyesight.For wind-heat hot eyes, swell and ache photophobia, screen of looking unfamiliar film, headache due to pathogenic wind-heat.
The research of the antiseptic property of test example 1 gained NMR of the present invention disinfectant (embodiment 5):
Test method: choose irony desktop, random division two blocks, test block and check plot, twoth district are divided into two block of cells more respectively, respectively for the forward and backward sampling of sterilization.Sterilization before with 5.0ml tryptone normal saline solution for sample solution, after sterilization with 5.0ml neutralizer for sample solution (neutralizer is the phosphate buffer containing 5g/L lecithin, 30g/L Tween 80 and 10g/L glycine), made for the present invention disinfectant is sparged the surface of a block of cells in test block, chlorohexidene disinfectant sparges the surface of a block of cells in check plot, disinfective action 10 minutes post-samplings, demarcate area with the plate of 5 × 5cm specification during sampling, forward and backward each sampling 20 parts of sterilizing is as positive controls sample and sterilized sample.
Result of the test: result shows, test block and the front natural bacteria count of control group district sterilization are 52cfu/cm
2and 55cfu/cm
2, through the made disinfectant disinfective action of the present invention after 10 minutes, surface, test block natural bacteria count is 1cfu/cm
2, and check plot is through the disinfective action of chlorohexidene disinfectant after 10 minutes, surperficial natural bacteria count is 3cfu/cm
2, illustrate that the sterilization effect of the made disinfectant of the present invention is comparatively remarkable.
It should be pointed out that embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. NMR disinfectant, is characterized in that, is prepared from primarily of following raw materials according, be mass parts: 3 mixed cresol 0.8-1.6, chlorhexidine gluconate 1-3, sodium dichloro cyanurate 2-4, sodium lauryl tri(oxyethyl) sulfate 4-6, deionized water 50-60, betel nut 6-10, Fructus meliae toosendan 4-9, chaulmoogra 9-17, capsule of weeping forsythia 12-18, Chinese violet 8-14, cordate houttuynia 4-9, Chinese pulsatilla 10-14, pipewort 5-10.
2. NMR disinfectant as claimed in claim 1, is characterized in that, 3 mixed cresol 1.0-1.4, chlorhexidine gluconate 1.5-2.5, sodium dichloro cyanurate 2.5-3.5, sodium lauryl tri(oxyethyl) sulfate 4.5-5.5, deionized water 52-58, betel nut 7-9, Fructus meliae toosendan 5-8, chaulmoogra 11-15, capsule of weeping forsythia 14-16, Chinese violet 10-12, cordate houttuynia 5-8, Chinese pulsatilla 11-13, pipewort 6-9.
3. NMR disinfectant as claimed in claim 1, is characterized in that, 3 mixed cresol 1.2, chlorhexidine gluconate 2, sodium dichloro cyanurate 3, sodium lauryl tri(oxyethyl) sulfate 5, deionized water 55, betel nut 8, Fructus meliae toosendan 6.5, chaulmoogra 13, the capsule of weeping forsythia 15, Chinese violet 11, cordate houttuynia 6.5, the Chinese pulsatilla 12, pipewort 7.5.
4. the preparation method of the NMR disinfectant as described in as arbitrary in claim 1-3, it is characterized in that, step is:
(1) cleaned by betel nut and break into pieces, boil with Fructus meliae toosendan and capsule of weeping forsythia mature vinegar, rear taking-up drains, and gets wheat bran and is placed in frying pan and has been heated to cigarette and emerges, be sprinkled into the betel nut, Fructus meliae toosendan and the capsule of weeping forsythia that drain, stir and take out when wheat bran be buff, sieve and remove wheat bran, pulverize raw material;
(2) get humus flava usta and be placed in heating in frying pan, when being heated to 40-60 DEG C, add the chaulmoogra of shelling, take out after slow fire stir-fries, sieve removes soil, dries in the air cool;
(3) get the Chinese pulsatilla and clean section, with ginger juice and poach 15-20 minute (preferred, to boil 17 minutes), then add Chinese violet and mix thoroughly, Guan Huo, adds a cover vexed, takes out, dries;
(4) decocted by adding distil water together with made to cordate houttuynia, pipewort and above-mentioned steps raw material, big fire is boiled and to be filtered after 25-35 minute that (preferred, 27-33 minute is boiled in big fire; Be more preferably, big fire boils 30 minutes), the distilled water that filter residue adds equivalent boils again, filters, merges twice gained filtrate, be concentrated into 1/6th of original volume, centrifugal removal of impurities, spraying dry, pulverizes, obtained medicinal powder;
(5) remove ionized water and be heated to 40 DEG C, add 3 mixed cresol and mix thoroughly, then add step (4) made medicinal powder to dissolving completely, be down to normal temperature, then add chlorhexidine gluconate and sodium dichloro cyanurate is mixed thoroughly, finally add sodium lauryl tri(oxyethyl) sulfate and mix, obtain disinfectant.
5. the preparation method of NMR disinfectant as claimed in claim 4, is characterized in that, step (1) mature vinegar boils 17-25 minute, and (preferred, mature vinegar boils 19-23 minute; Be more preferably, mature vinegar boils 21 minutes).
6. the preparation method of NMR disinfectant as claimed in claim 4, is characterized in that, step (2) is heated to 45-55 DEG C (preferred, to be heated to 50 DEG C).
7. the preparation method of NMR disinfectant as claimed in claim 4, is characterized in that, step (3) is added a cover and (preferably, added a cover vexed 14-16 minute in vexed 12-18 minute; Be more preferably, add a cover vexed 15 minutes).
8. the preparation method of NMR disinfectant as claimed in claim 4, is characterized in that, the amount of step (4) distilled water by decoctions material quality 5-7 doubly (preferably, distilled water amount by 6 times of decoction material quality).
9. the preparation method of NMR disinfectant as claimed in claim 4, is characterized in that, the distilled water that step (4) filter residue adds equivalent boil again 20-30 minute (preferred, then boil 22-28 minute; Be more preferably, then boil 25 minutes).
10. the preparation method of NMR disinfectant as claimed in claim 4, is characterized in that, step (4) was pulverized 180-260 mesh sieve and (preferably, pulverized 200-240 mesh sieve; Be more preferably, pulverized 220 mesh sieves).
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Address after: 725000 healthy city in Shaanxi province Hanbin District Jinzhou Road No. 74 South District 1 building 2-602 Applicant after: Shi Chunyan Address before: 250000 Shandong province Ji'nan City flyover District Dikou Road No. 110 Applicant before: Shi Chunyan |
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Application publication date: 20160511 |