CN105535801A - Medicine for treating idiopathic edema - Google Patents
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- CN105535801A CN105535801A CN201610124111.2A CN201610124111A CN105535801A CN 105535801 A CN105535801 A CN 105535801A CN 201610124111 A CN201610124111 A CN 201610124111A CN 105535801 A CN105535801 A CN 105535801A
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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Abstract
The invention relates to a medicine for treating idiopathic edema. The medicine is prepared from raw materials in parts by weight as follows: 8 parts of cowherb seeds, 10 parts of areca peel, 14 parts of plantain seeds, 12 parts of hiraute shiny bugleweed herbs, 9 parts of papermulberry fruits, 5 parts of tsaoko amomum fruits, 10 parts of fortune eupatorium herbs and 9 parts of himalayan teasel roots. The cowherb seeds can activate blood circulation to promote menstruation and eliminate carbuncles; the areca peel can expel flatulence, regulate qi by alleviation of mental depression, promote urination and eliminate swelling; the plantain seeds can clear heat, promote urination, excrete dampness, stop diarrhea, improve eyesight and eliminate phlegm; the hiraute shiny bugleweed herbs can activate blood to remove stasis, promote urination, eliminate swelling, remove toxicity and eliminate carbuncles; the papermulberry fruits can tonify the kidney, clear liver heat, improve the eyesight and promote urination; the tsaoko amomum fruits can eliminate dampness, warm the middle warmer, eliminate phlegm and prevent malaria; the fortune eupatorium herbs can relieve summer-heat, dissipate dampness, repel foulness and regulate the middle warmer; the himalayan teasel roots can tonify the liver and the kidney, strength tendons and bones, regulate blood vessels and stop metrorrhagia and metrostaxis. The medicinal raw materials are combined to have the efficacy of urination promotion, swelling elimination, dampness and heat removal, liver soothing, qi regulation, spleen invigorating and diarrhoea stopping. Clinical experiments prove that the medicine can treat idiopathic edema safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of idiopathic edema.
Background technology
Idiopathic edema (idiopathicedema), also known as " water retention obesity ", " pure water-sodium retention disease ", " periodically edema " etc., is one comparatively common in edema.Edema is from classification intentionally source property, kidney source property, liver source property, dystrophic etc., these edema are all have obvious reason to seek, and idiopathic edema, can look into without clear and definite reason with regard to peculiar, definite pathogenic factor is not fully aware of yet, therefore titled with " idiopathic " word.Although its cause of disease is understood fully at present not yet completely, say it is that water and salt metabolic disturbance for the one caused because of many unbalance of system such as endocrine, blood vessel, nerve from the angle of physiological pathology, extracellular fluid has abnormal increase at subcutaneous space.Fortunately, idiopathic edema is mostly without serious consequence, and the state of an illness, often in going round and beginning again, does not generally have obvious progress.This disease also has much feature in clinical manifestation, has many clues and traces to look into, and suffering from patient can autognostic accordingly.Primary disease is more common in the fat women of 20 ~ 50 years old period of duration concomitant fertilizer, increases closely related for main clinical characteristics with edema and menstrual cycle and body weight.Primary disease prognosis bona.
Idiopathic edema belongs to " edema " category of the traditional Chinese medical science.
Feature
The feature of the idiopathic edema mainly generation of edema and position has close relationship.Stand for a long time or movable, eat salt after occur or increase the weight of, horizontal position alleviates to disappearance again after having a rest gradually.Edema often occurs in morning, face and hand obvious, afternoon with lower limb and foot remarkable.In addition, patient sooner or later body weight change is comparatively large, and before going to bed, weight ratio WA on average can increase by 1 kilogram or more.Although the idiopathic edema course of disease is long, major part can spontaneous recovery.
Performance
1. edema or edema: be common in postpubertal women, how after the activity of vertical position or occur pitting edema before foot, ankle, shin afternoon, and has some patients to occur daystart eyelid, facial edema, the swelling of upper limb far-end; The generation of some patients edema is relevant with hot climate or menstrual cycle.Before sleeping night, comparatively morning, WA body weight increased, and after the night of sleeping, edema disappears, and loses weight.
2. fat: about the idiopathic edema patient of half has obesity, and edema further add the body weight of patient.
3. have a headache: because intracranial edema can cause patient to have a headache.
4. can there is similar rheumatismal systemic pain due to the patient of tiny blood vessels obstacle in part after long-time upright.
5. orthostatic hypotension can be there is, the performance of autonomic nervous function imbalance.
Drug therapy
1. the definite pathogeny due to idiopathic edema is not clear, so there is no the Therapeutic Method of very specially good effect at present, but this is not mean to obtain good curative effect.Good mental state, happy emotion play a part certain in treatment.Salinity in cutting down one's diet, every day, Sal was no more than 5 grams.Suitable minimizing amount of drinking water.Strive for there is one flat bed rest period at noon, salt too much in body is had more discharge " halfway " of a day.If working condition allows, can suitably raise two lower limb, in order to avoid because of gravity relation, water salt is too much detained at lower limb.Stretch socks and Elastic bandage can be tried out, in order to lower limb vascular backflow, alleviate edema.Take the medicine of regulating plant function of nervous system in right amount, when edema is more obvious, can diuretic be taken.
2. treatment by Chinese herbs
Chinese traditional treatment is started with marrow, whole body therapeutic, and make disease start to take a turn for the better, human body recovers normal physiological function.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of idiopathic edema, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing idiopathic edema.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine being used for the treatment of idiopathic edema, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Semen Vaccariae 8 parts, Pericarpium Arecae 10 parts, Semen Plantaginis 14 parts, Herba Lycopi 12 parts, Fructus Broussonetiae 9 parts, Fructus Tsaoko 5 parts, Herba Eupatorii 10 parts, Radix Dipsaci 9 parts.
Below in conjunction with theories of Chinese materia medica, beneficial effect of the present invention is described:
Inventor thinks, the main in love will internal injury of the cause of disease of idiopathic edema, the liver failing to maintain the normal flow of QI; Or congenital defect, kidney qi deficiency in origin; Or lack of proper care after one's birth, injure spleen kidney etc., all make water transport not normal, overflowing, it is swollen to flood in skin.Pathological change is liver,spleen,kidney damage, functional disorder.Liver controlling conveyance and dispersion, catharsis is normal, then mechanism of qi passes unimpeded, and blood and water Tianjin are normally run.If depression of liver-QI, functional activity of QI being not smooth, then blood stasis water resistance, pathogenic water overflowing in the subcutaneous tissues and edema.The spleen has the function to transport and transform nutrients, if eating and drinking without temperance, or lose the day after tomorrow foster, and cause spleen and lose Wen Yun, then phlegm resistance, the edema in skin of overflowing.Kidney is the official of main water, if congenital defect, or the kidney usually involved in chronic disease, or impairment of the kidney due to indulgence in sexual activities, punching in menstrual period is appointed in addition more needs kidney essense to supplement nutrition, and kidney essense runs off with menses, and kidney yang is thereupon impaired, can not promote the circulation of qi and water, and the wet skin that overflows of water surveys edema aggravation in menstrual period.In addition, damp-stagnancy heat-transformation, damp and hot heap soil or fertilizer over and around the roots is contained, strongly fragrant in skin, also sees edema.Therefore treatment then takes warming YANG to promote diuresis, promoting flow of QI and blood, dispelling phlegm and eliminating dampness.
The present invention uses: Semen Vaccariae promoting blood circulation to restore menstrual flow, unable to suck milk eliminating carbuncle; Pericarpium Arecae therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, line water detumescence; Semen Plantaginis clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, improving eyesight is eliminated the phlegm; Herba Lycopi's blood circulation promoting and blood stasis dispelling, line water detumescence, removing toxicity for eliminating carbuncles; Fructus Broussonetiae the kidney invigorating liver heat removing, improving eyesight diuresis; Fructus Tsaoko dampness warming middle-JIAO, eliminate the phlegm preventing the attack (or recurrence) of malaria; Herba Eupatorii expelling summer-heat and damp, ward off dirty and in; Radix Dipsaci invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, only metrorrhagia.All medicines share, and reach effect that inducing diuresis to remove edema, point dampness removing heat, depressed liver-energy dispersing and QI regulating, spleen invigorating are rushed down.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects 162 routine idiopathic edema female patients between in March ,-2015 in March, 2011 altogether.Be divided at random: treatment group 81 example, matched group 81 example.Wherein 36 ~ 66 years old treatment group age, the course of disease 3 months ~ 7 years; Between 35 ~ 64 years old age of matched group, the course of disease 3 months ~ 6 years.The data there was no significant differences such as two groups of sexes, age, courses of disease, have comparability.
Diagnostic criteria
1. get rid of and cause the known cause of disease of water-sodium retention, as disease and Drug edema such as heart, liver, kidney, lungs, hypothyroidism, do vascular factor except two lower limb arteriovenous color ultrasound and cause the obstacle that refluxes.
2. vertical clinostatism water load test is positive.Vertical clinostatism water load test method: calculate ideal body weight before test, stops using medicine at least two weeks such as diuretic.Test 12h on an empty stomach at first day night, early morning, 8:00 instructed patient to drink water 20ml/kg, continued more than 30min, empty bladder, collected 4h urine. and whole process patient keeps clinostatism.Test and within second day, repeat above test.Whole process patient keeps vertical position.The excretion of vertical position water is less than 70% of the excretion of clinostatism water, and the vertical clinostatism water load test of prompting is positive. support the diagnosis of idiopathic edema.
1. inclusive criteria meets diagnostic criteria; 2. 18 ~ 70 years old age; 3. compliance is good; 4. Informed Consent Form is signed voluntarily.
Exclusion standard is gestation, women breast-feeding their children 1.; 2. severe cardiac, lung, liver, renal disease patient is suffered from; 3. spiritedness systemic disease, can not partner treatment person; 4. allergic constitution and those who are allergic to this drug.
2, Therapeutic Method
The powder that the oral the present invention for the treatment of group obtains according to specific embodiment 2, every day 3 times.Treat 1 month.
Matched group oral spironolactone sheet, each 20mg, every day 1 time.Treat 1 month.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
1. fully recover: edema all disappears, weight loss, muscle power, appetite increase, and urine volume is normal, and 6 months without recidivist;
2. effective: edema, to lose weight, muscle power, appetite are improved, and hydrouria, follows up a case by regular visits to February without recidivist;
3. invalid: all unchanged person of edema, body weight, muscle power, appetite and urine volume.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment idiopathic edema, and cure rate is high.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Semen Vaccariae 8 grams, Pericarpium Arecae 10 grams, Semen Plantaginis 14 grams, Herba Lycopi 12 grams, Fructus Broussonetiae 9 grams, Fructus Tsaoko 5 grams, Herba Eupatorii 10 grams, Radix Dipsaci 9 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of idiopathic edema.Oral, daily once.
Embodiment 2
Take: Semen Vaccariae 8 grams, Pericarpium Arecae 10 grams, Semen Plantaginis 14 grams, Herba Lycopi 12 grams, Fructus Broussonetiae 9 grams, Fructus Tsaoko 5 grams, Herba Eupatorii 10 grams, Radix Dipsaci 9 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of idiopathic edema.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Take: Semen Vaccariae 8 grams, Pericarpium Arecae 10 grams, Semen Plantaginis 14 grams, Herba Lycopi 12 grams, Fructus Broussonetiae 9 grams, Fructus Tsaoko 5 grams, Herba Eupatorii 10 grams, Radix Dipsaci 9 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of idiopathic edema.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. one kind is used for the treatment of the medicine of idiopathic edema, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Semen Vaccariae 8 parts, Pericarpium Arecae 10 parts, Semen Plantaginis 14 parts, Herba Lycopi 12 parts, Fructus Broussonetiae 9 parts, Fructus Tsaoko 5 parts, Herba Eupatorii 10 parts, Radix Dipsaci 9 parts.
2. a kind of medicine being used for the treatment of idiopathic edema as claimed in claim 1, it is characterized in that, its preparation method is: take: Semen Vaccariae 8 parts, Pericarpium Arecae 10 parts, Semen Plantaginis 14 parts, Herba Lycopi 12 parts, Fructus Broussonetiae 9 parts, Fructus Tsaoko 5 parts, Herba Eupatorii 10 parts, Radix Dipsaci 9 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of medicine being used for the treatment of idiopathic edema as claimed in claim 1, it is characterized in that, its preparation method is: take: Semen Vaccariae 8 parts, Pericarpium Arecae 10 parts, Semen Plantaginis 14 parts, Herba Lycopi 12 parts, Fructus Broussonetiae 9 parts, Fructus Tsaoko 5 parts, Herba Eupatorii 10 parts, Radix Dipsaci 9 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of medicine being used for the treatment of idiopathic edema as claimed in claim 1, it is characterized in that, its preparation method is: take: Semen Vaccariae 8 parts, Pericarpium Arecae 10 parts, Semen Plantaginis 14 parts, Herba Lycopi 12 parts, Fructus Broussonetiae 9 parts, Fructus Tsaoko 5 parts, Herba Eupatorii 10 parts, Radix Dipsaci 9 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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CN201610124111.2A CN105535801A (en) | 2016-03-04 | 2016-03-04 | Medicine for treating idiopathic edema |
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CN201610124111.2A CN105535801A (en) | 2016-03-04 | 2016-03-04 | Medicine for treating idiopathic edema |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102366506A (en) * | 2011-09-13 | 2012-03-07 | 成都绿迪科技有限公司 | Traditional Chinese medicine composition for treating idiopathic edema |
CN103893724A (en) * | 2014-03-29 | 2014-07-02 | 邓林生 | Traditional Chinese medicine composition for treating liver depression and spleen deficiency type idiopathic edema of women |
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2016
- 2016-03-04 CN CN201610124111.2A patent/CN105535801A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102366506A (en) * | 2011-09-13 | 2012-03-07 | 成都绿迪科技有限公司 | Traditional Chinese medicine composition for treating idiopathic edema |
CN103893724A (en) * | 2014-03-29 | 2014-07-02 | 邓林生 | Traditional Chinese medicine composition for treating liver depression and spleen deficiency type idiopathic edema of women |
Non-Patent Citations (1)
Title |
---|
窦景云等: "中医药治疗特发性水肿规律的频数分析", 《中国中医药现代远程教育》 * |
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Application publication date: 20160504 |