CN105519538A - Sterilization composition containing fluxapyroxad and meptyldinocap - Google Patents
Sterilization composition containing fluxapyroxad and meptyldinocap Download PDFInfo
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- CN105519538A CN105519538A CN201510971346.0A CN201510971346A CN105519538A CN 105519538 A CN105519538 A CN 105519538A CN 201510971346 A CN201510971346 A CN 201510971346A CN 105519538 A CN105519538 A CN 105519538A
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- acid amides
- fluorine azoles
- nitre benzene
- azoles bacterium
- bacterium ester
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/06—Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a sterilization composition containing fluxapyroxad and meptyldinocap. The sterilization composition comprises effective components of fluxapyroxad and meptyldinocap, the weight ratio of fluxapyroxad to meptyldinocap is 1:10-10:1, and the weight percentage of the total weight of fluxapyroxad and meptyldinocap in the composition is 2%-90%. According to practical application needs, the sterilization composition can be made into one of an emulsion in water, a microemulsion, a suspending agent, a wettable powder and water dispersible granules. The sterilization composition has a significant synergistic effect on cucumber, grape and strawberry powdery mildew, also reduces the use amount of pesticides, reduces the residual quantity of the pesticides on plants, relieves the environmental pollution, delays the generation of drug resistance of diseases, and prolongs the service life of the pesticides.
Description
Technical field
The present invention relates to a kind of bactericidal composition containing fluorine azoles bacterium acid amides and nitre benzene bacterium ester, is with fluorine azoles bacterium acid amides and nitre benzene bacterium ester for active ingredient, for preventing and treating cucumber, grape, powdery mildew of strawberry.
Background technology
The resistance problem of agricultural disease is a global problem, is the emphasis problem that agricultural science and technology worker pays close attention to always.Along with the continuity year in year out of disease chemical control, the increase of Pesticide use amount and not scientifical use agricultural chemicals, germ resistance is day by day serious, and the germ kind producing resistance is on the increase.Meanwhile, the use agricultural chemicals of high strength, causes Practice for Pesticide Residue in Agricultural Products to exceed standard, environmental pollution and the increase of peasant's drug cost etc., is unfavorable for agricultural sustainable development.Therefore, the bactericide agricultural chemicals of efficient, the low toxicity of research and development, environmental protection has positive effect to agricultural sustainable development.
Fluorine azoles bacterium acid amides, English name: fluxapyroxad, chemical name: 3-(difluoromethyl)-1-methyl-N-(3,4,5-trifluoro [the two benzene of 1,1-]-2-base))-1H-pyrazole-4-carboxamide, fluorine azoles bacterium acid amides is succinate dehydrogenase inhibitors, potent selectivity bactericidal action is had, for the water prevention rice sheath blight, sigatoka, powdery mildew of strawberry, powdery mildew of cucumber etc. to cereal, soybean, corn, oil crop and banana, tomato, grape etc.
Nitre benzene bacterium ester, English name: meptyldinocap, chemical name: 2,4-dinitro-6-(1-methylheptyl) benzene crotonates, nitre benzene bacterium ester is mitochondrial respiratory inhibitor, namely passes through at the electro transfer of cytochrome B cl to cromoci, thus suppresses mitochondrial breathing, there is prevention, treatment and shoveling function, on fruit tree, vegetables, prevent and treat powdery mildew excellent effect.
The mixture of different pesticide species is the common methods of control agricultural pest.Being screened by formulation of pesticide, filter out rational formula, can effectively improve actual control efficiency, reduce dosage, reduce costs, delay the drug-fast generation of damage by disease and insect, is the important means that agricultural synthesis is administered.Fluorine azoles bacterium acid amides has good interior absorption, can doing to conduct in object, and therefore application after plant morbidity, its therapeutic action clearly.Nitre benzene bacterium ester does not have interior absorption, shows to form medicine film after dispenser plant, and main rising is protected and therapeutic action, and the lasting period is shorter.Fluorine azoles bacterium acid amides and nitre benzene bacterium ester composite after, there is interior suction therapeutic activity and protectiveness simultaneously, not only extend the product lasting period, also enhance the preventive effect to disease.
The recipe determination of the present inventor to fluorine azoles bacterium acid amides and nitre benzene bacterium ester conducts in-depth research, find that fluorine azoles bacterium acid amides and nitre benzene bacterium ester carry out mixture and have obvious synergistic effect in certain mixed ratio scope to multiple fungi, after further study, the present invention is completed.
Composition and the application of fluorine azoles bacterium acid amides and nitre benzene bacterium ester there is no report at present.
Summary of the invention
The technical problem that the present invention solves be to provide a kind of efficient, low toxicity and the lasting period long, effectively can prevent and treat a kind of bactericidal composition containing fluorine azoles bacterium acid amides and nitre benzene bacterium ester of agricultural fungal evil.
For solving the problem, the technical solution adopted in the present invention is: a kind of bactericidal composition containing fluorine azoles bacterium acid amides and nitre benzene bacterium ester, active ingredient is fluorine azoles bacterium acid amides and nitre benzene bacterium ester, the weight ratio of fluorine azoles bacterium acid amides and nitre benzene bacterium ester is 1:10 ~ 10:1, fluorine azoles bacterium acid amides and nitre benzene bacterium ester weight summation in the composition percentage by weight are 2% ~ 90%, and all the other are agriculturally allow to use and acceptable insecticides adjuvant.
Bactericidal composition of the present invention according to well known to a person skilled in the art method, can be configured to the one in aqueous emulsion, microemulsion, suspending agent, wetting powder, water dispersible granules.
Bactericidal composition of the present invention is also containing the auxiliary agent of preparation needed for pesticidal preparations, auxiliary agent is the mixing of one or more in solvent, emulsifier, wetting agent, stabilizing agent, dispersant, thickener, pH adjusting agent, defoamer, antifreezing agent, packing agent etc., be known substance, various auxiliary agents conventional in pesticidal preparations, can change to some extent according to different situations, be not particularly limited.
Bactericidal composition described in the invention, can finished product preparation form provide, namely in composition, each material mixes, and the composition of composition also can provide by unit dose form, directly mixes in bucket or tank, be then diluted to desired concn before using.
Bactericidal composition of the present invention, for preventing and treating cucumber, grape, powdery mildew of strawberry.
A kind of bactericidal composition containing fluorine azoles bacterium acid amides and nitre benzene bacterium ester provided by the invention, usually adopts spray method to use, also can adopt other operation techniques agriculturally applied as required.
One provided by the invention contains fluorine azoles bacterium acid amides and nitre benzene bacterium ester bactericidal composition has following beneficial effect:
1, bactericidal composition provided by the invention, obvious synergistic effect is shown in certain ratio range, the control efficiency of composition to germ is significantly improved than single dose, reduce the using dosage of agricultural chemicals, decrease times for spraying, reduce drug cost, decrease the adverse effect of agricultural chemicals to ecotope.
2, bactericidal composition provided by the invention, the mechanism of action is different, can overcome the shortcoming that long-term single use easily produces resistance, extends the service life of medicament, to the comprehensive regulation important in inhibiting of germ resistance.
3, bactericidal composition provided by the invention, drug effect plays rapidly, and the lasting period is long, and use cost is low, easy to use, time saving and energy saving, and it applies huge economic benefit and social benefit.
Embodiment
In order to make object of the present invention, technical scheme and advantage more short and sweet, the following specific embodiment of the present invention is described, but the present invention is only limitted to absolutely not these embodiments.The following stated is only the good embodiment of the present invention, only for describing the present invention, can not be interpreted as the restriction to scope of the present invention.It should be pointed out that all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Content described in embodiment is all weight percentage.
Embodiment 1:33% fluorine azoles bacterium acid amides nitre benzene bacterium ester suspending agent
First mixed by other auxiliary agent, in clipper, shear-mixed is even, then adds fluorine azoles bacterium acid amides and nitre benzene bacterium ester, grinds 2 ~ 3h, make a diameter all at below 5mm, can obtain 33% fluorine azoles bacterium acid amides nitre benzene bacterium ester suspending agent in ball crusher.
Embodiment 2:12% fluorine azoles bacterium acid amides nitre benzene bacterium ester aqueous emulsion
First fluorine azoles bacterium acid amides and nitre benzene bacterium ester, methyl naphthalene, Sorbitan fatty acid ester are mixed, dissolve and become uniform oil phase.Again part water and other auxiliary agents are mixed, dissolve and become uniform aqueous phase.Then oil phase is added aqueous phase while high-speed stirred in a kettle., slowly add water to and reach phase inversion point, carry out high speed shear afterwards, and add remaining water, shear about 30min, 12% fluorine azoles bacterium acid amides nitre benzene bacterium ester aqueous emulsion can be obtained.
Embodiment 3:12% fluorine azoles bacterium acid amides nitre benzene bacterium ester microemulsion
First fluorine azoles bacterium acid amides and nitre benzene bacterium ester fatty acid methyl ester are dissolved completely, and then add other auxiliary agent, mix, finally add water, after fully stirring, 12% fluorine azoles bacterium acid amides nitre benzene bacterium ester microemulsion can be obtained.
Embodiment 4:50% fluorine azoles bacterium acid amides nitre benzene bacterium ester wetting powder
Fluorine azoles bacterium acid amides and nitre benzene bacterium ester, other auxiliary agent are fully stirred in stirred tank, mixes after airslide disintegrating mill is pulverized, 50% fluorine azoles bacterium acid amides nitre benzene bacterium ester wetting powder can be obtained.
Embodiment 5:40% fluorine azoles bacterium acid amides nitre benzene bacterium ester water dispersible granules
Fluorine azoles bacterium acid amides and nitre benzene bacterium ester, other auxiliary agent will be had to mix, pulverize with micro jet, and add after mediating after carrying out granulation, drying, screening in fluidized-bed granulation dryer, 40% fluorine azoles bacterium acid amides nitre benzene bacterium ester water dispersible granules can be obtained.
Embodiment 6:30% fluorine azoles bacterium acid amides nitre benzene bacterium ester suspending agent
First mixed by other auxiliary agent, in clipper, shear-mixed is even, then adds fluorine azoles bacterium acid amides and nitre benzene bacterium ester, grinds 2 ~ 3h, make a diameter all at below 5mm, can obtain 30% fluorine azoles bacterium acid amides nitre benzene bacterium ester suspending agent in ball crusher.
Embodiment 7:55% fluorine azoles bacterium acid amides nitre benzene bacterium ester wetting powder
Concrete operation step is: fluorine azoles bacterium acid amides and nitre benzene bacterium ester, other auxiliary agent are fully stirred in stirred tank, mixes, can obtain 55% fluorine azoles bacterium acid amides nitre benzene bacterium ester wetting powder after airslide disintegrating mill is pulverized.
Embodiment 8: indoor bioassay
The present composition adopts field cauline leaf spray-on process dispenser (having water membrane to be advisable with crop leaf surface) to crop powdery mildew tests such as cucumber, grape, strawberries, spraying process is carried out on June 7th, 2015, chemical sprayer tool adopts manual sprayer (liquid capacity is about 2.0L), every 10 days spray medicines once, continuous spraying 2 times.Often process selects uniform crop 20 blades of falling ill as efficacy of medicine observing object, and each process repeats for 3 times.
Investigation method:
0 grade: without scab;
1 grade: lesion area accounts for less than 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for more than 50% of whole leaf area.
According to survey data, calculate disease index and the control efficiency of each process.
Disease index presses formulae discovery, and result of calculation retains 2 significant digits:
When carrying out drug combination toxicity test, this test adopts Wadley method to calculate the coefficient of synergism (SR) of mixture, evaluates the synergy type of mixture.
Wadley method: the synergistic effect evaluating pharmacy mix according to coefficient of synergism (SR), namely SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 is synergistic function.Coefficient of synergism (SR) calculates by formula (1), (2):
In formula:
X1--mixture EC
50theoretical value, unit is milligrams per liter (mg/L);
P
a--the percentage composition of A in mixture, unit is percentage (%);
P
b--the percentage composition of B in mixture, unit is percentage (%);
The EC of A in A--mixture
50value, unit is milligrams per liter (mg/L);
The EC of B in B--mixture
50value, unit is milligrams per liter (mg/L).
In formula:
The coefficient of synergism of SR--mixture;
The EC of X1--mixture
50theoretical value, unit is milligrams per liter (mg/L);
The EC of X2--mixture
50measured value, unit is milligrams per liter (mg/L).
Table 1, fluorine azoles bacterium acid amides and nitre benzene bacterium ester are to the synergy result of powdery mildew of cucumber germ
As can be seen from Table 1, fluorine azoles bacterium acid amides and nitre benzene bacterium ester composite in the weight ratio of 1:10-10:1, synergistic effect is shown as to powdery mildew of cucumber.
Table 2, fluorine azoles bacterium acid amides and nitre benzene bacterium ester are to the synergy result of powdery mildew of strawberry germ
As can be seen from Table 2, fluorine azoles bacterium acid amides and nitre benzene bacterium ester composite in the weight ratio of 1:10-10:1, synergistic effect is shown as to powdery mildew of strawberry.
Table 3, fluorine azoles bacterium acid amides and nitre benzene bacterium ester are to the synergy result of grape powdery mildew germ
As can be seen from Table 3, fluorine azoles bacterium acid amides and nitre benzene bacterium ester composite in the weight ratio of 1:10-10:1, synergistic effect is shown as to grape powdery mildew.
Embodiment 9: fluorine azoles bacterium acid amides and nitre benzene bacterium ester composition are for preventing and treating cucumber, strawberry, grape powdery mildew field trial.
Test site is positioned at Ma An town, Huizhou, Huarong County, Hunan Province, Gongan County, Hubei Province, and test adopts spray-on process.Adopt 20% fluorine azoles bacterium amide suspending agents, 36% nitre benzene bacterium emulsifiable concentrate medicament in contrast, 9 chemicals treatment are established in test altogether, each process repeats for 4 times, the sick number of sheets of crop is investigated before dispenser, within after dispenser 7 days, 15 days, respectively investigate a control efficiency, record the disease number of sheets, calculate control efficiency, result of the test is as shown in table 4,5,6.
The combination of table 4, fluorine azoles bacterium acid amides and nitre benzene bacterium ester prevents and treats powdery mildew of cucumber result of the test
Table 5, fluorine azoles bacterium acid amides and nitre benzene bacterium ester combination control powdery mildew of strawberry result of the test
Table 6, fluorine azoles bacterium acid amides and nitre benzene bacterium ester combination control grape powdery mildew result of the test
As can be seen from table 4,5,6, example of formulations 1-7, the effect of control cucumber, strawberry, grape powdery mildew is better than the process of each contrast single dose, fluorine azoles bacterium acid amides is described and nitre benzene bacterium ester is composite can improve control efficiency, reduce the using dosage of agricultural chemicals, decrease the impact of agricultural chemicals on environment, reduce drug cost.
Claims (3)
1. one kind contains the bactericidal composition of fluorine azoles bacterium acid amides and nitre benzene bacterium ester, it is characterized in that: active ingredient is fluorine azoles bacterium acid amides and nitre benzene bacterium ester, the weight ratio of fluorine azoles bacterium acid amides and nitre benzene bacterium ester is 1:10 ~ 10:1, and fluorine azoles bacterium acid amides and nitre benzene bacterium ester weight summation in the composition percentage by weight are 2% ~ 90%.
2. a kind of bactericidal composition containing fluorine azoles bacterium acid amides and nitre benzene bacterium ester according to claim 1, is characterized in that: the formulation of described bactericidal composition is the one of aqueous emulsion, microemulsion, suspending agent, wetting powder, water dispersible granules.
3. a kind of bactericidal composition containing fluorine azoles bacterium acid amides and nitre benzene bacterium ester described in claim 1 is preventing and treating the application in cucumber, grape, powdery mildew of strawberry.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510971346.0A CN105519538A (en) | 2015-12-20 | 2015-12-20 | Sterilization composition containing fluxapyroxad and meptyldinocap |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510971346.0A CN105519538A (en) | 2015-12-20 | 2015-12-20 | Sterilization composition containing fluxapyroxad and meptyldinocap |
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| CN105519538A true CN105519538A (en) | 2016-04-27 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106719722A (en) * | 2016-05-31 | 2017-05-31 | 徐月苗 | A kind of bactericidal composition and its application in agricultural chemicals |
| CN106857539A (en) * | 2017-03-13 | 2017-06-20 | 深圳诺普信农化股份有限公司 | A kind of bactericidal composition containing biphenyl pyrrole bacterium amine and its application |
| CN106982840A (en) * | 2016-01-20 | 2017-07-28 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| EP3412150A1 (en) * | 2017-06-06 | 2018-12-12 | Basf Se | Mixtures of meptyldinocap with sdhi fungicides |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101257798A (en) * | 2005-08-05 | 2008-09-03 | 巴斯福股份公司 | Fungicidal mixtures containing substituted 1-methyl pyrazol-4-yl carboxylic acid anilides |
-
2015
- 2015-12-20 CN CN201510971346.0A patent/CN105519538A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101257798A (en) * | 2005-08-05 | 2008-09-03 | 巴斯福股份公司 | Fungicidal mixtures containing substituted 1-methyl pyrazol-4-yl carboxylic acid anilides |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106982840A (en) * | 2016-01-20 | 2017-07-28 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN106719722A (en) * | 2016-05-31 | 2017-05-31 | 徐月苗 | A kind of bactericidal composition and its application in agricultural chemicals |
| CN106857539A (en) * | 2017-03-13 | 2017-06-20 | 深圳诺普信农化股份有限公司 | A kind of bactericidal composition containing biphenyl pyrrole bacterium amine and its application |
| EP3412150A1 (en) * | 2017-06-06 | 2018-12-12 | Basf Se | Mixtures of meptyldinocap with sdhi fungicides |
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Application publication date: 20160427 |