CN105487099A - Radioactive photoelectric detector and detection method thereof - Google Patents

Radioactive photoelectric detector and detection method thereof Download PDF

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Publication number
CN105487099A
CN105487099A CN201410514932.8A CN201410514932A CN105487099A CN 105487099 A CN105487099 A CN 105487099A CN 201410514932 A CN201410514932 A CN 201410514932A CN 105487099 A CN105487099 A CN 105487099A
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China
Prior art keywords
signal
radioactivity
photodetector
electric signal
summing circuit
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CN201410514932.8A
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Chinese (zh)
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陈劲云
陈守田
李兰
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Shenzhen Basda Medical Co Ltd
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Shenzhen Basda Medical Co Ltd
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Priority to CN201410514932.8A priority Critical patent/CN105487099A/en
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  • Measurement Of Radiation (AREA)
  • Nuclear Medicine (AREA)

Abstract

The invention provides a radioactive photoelectric detector used to detect radioactive substances in viscera organs and generate radioactive substance distribution images. The radioactive photoelectric detector comprises a signal collector, a plurality of photomultipliers, a summing circuit, a discrimination device and an imaging device. The signal collector is close to a viscera organ. The plurality of photomultipliers are arranged on one side of the signal collector, far away from the viscera organ. The input end of the summing circuit is directly electrically connected with the photomultiplier. The output end of the summing circuit is electrically connected with the imaging device. The input end of the discrimination device is electrically connected with the output end of the summing circuit. The output end of the discrimination device is electrically connected with the imaging device. Compared with the prior art, the discrimination device of the radioactive photoelectric detector denoises a summed electric signal, and intensity of the sum of output signals is improved while weak signals are effectively removed, so that photon collection efficiency is improved and image quality is improved.

Description

A kind of radioactivity photodetector and detection method thereof
Technical field
The present invention relates to a kind of radiomaterial measurement mechanism, particularly relate to a kind of sniffer for nucleus medical image and detection method thereof.
Background technology
Be that several hours even radioactive isotope of a few minutes are introduced in vivo by the half life period, and follow the trail of the radioactive isotope in internal organs, image is generated according to the radioisotopic distribution situation tracked and dynamic change, in this, as the basis of the diagnosis of disease, treatment and research, it is the important clinical application of current nuclear medicine.The comparatively normal nuclear medicine checkout equipment used comprises gammacamera, single photon emission computed tomography takes a picture (SPECT), Positron emission computed tomography (PET) etc.
The detection mode of nuclear medicine checkout equipment is: the radioactive isotope in internal organs sends gamma-rays, and gamma-rays is irradiated to NaI (T1) crystal generation photoelectric effect, produces fluorescence; Tens of the photomultipliers by definite shape arranged distribution (PMT) absorb faint fluorescence, export the XY position signalling of electric signal and reaction incident gamma ray position; Respectively denoising is screened to electric signal by discriminator circuit, subsequently by the multiple electric signal summations after denoising; Electric signal after the XY signal of reaction incident gamma ray position and summation is converted to digital signal through ADC, in computing machine, forms gamma-rays distribution plan.
At present, there is the problem that quantity of information is low, spatial resolution is poor gathered in nuclear medical imaging, need to improve sensitivity and resolution, obtain high-quality image as far as possible with few radioactive trace of trying one's best, thus picture quality is improved on Radioactivity Measurement basis suffered by minimizing patient.
Summary of the invention
The object of this invention is to provide a kind of radioactivity photodetector, it is by improving signal collection method, and the intensity increasing signal improves the collection efficiency of photon, thus improves picture quality.
Another object of the present invention is to provide a kind of detection method of radioactivity photodetector, and it is by improving signal collection method, and the intensity increasing signal improves the collection efficiency of photon, thus improves picture quality.
For achieving the above object, the invention provides a kind of radioactivity photodetector, radiomaterial distributed image is generated for the radiating matter detected in internal organs, described radioactivity photodetector comprises signal picker, several photomultipliers, summing circuit, screening device and imaging device, described signal picker is near internal organs; Several photomultipliers are arranged at the side of described signal picker away from internal organs; The input end of described summing circuit is directly electrically connected described photomultiplier, and the output terminal of described summing circuit is electrically connected described imaging device; The input end of described screening device is electrically connected the output terminal of described summing circuit, and the output terminal of described screening device is electrically connected described imaging device.
Radioactivity photodetector provided by the invention, the output terminal of photomultiplier is directly connected in summing circuit; The output terminal of summing circuit is connected to screening device, and total electric signal that summing circuit exports by screening device carries out examination denoising, and the total electric signal after denoising is sent to imaging device.Compared with prior art, radioactivity photodetector provided by the invention, screening device carries out denoising to the total electric signal after summation, improves the intensity of output signal while effectively removing weak signal, thus improves photon collection efficiency, improves picture quality.
Preferably, photomultiplier described in several is arranged in a row near one end of described signal picker row plane, and described arrangement plane is parallel to described signal picker, and described arrangement plane is just to described signal picker.
Particularly, photomultiplier described in several is the arrangement of honeycomb fashion matrix.
For achieving the above object, the present invention also provides a kind of detection method of radioactivity photodetector, comprises the following steps: the ray that S1, absorption radiating matter send, and produces fluorescence signal; S2, gather fluorescence signal respectively in some positions, produce electric signal through photoelectric effect, and some electric signal summations are generated total electric signal; S3, screen total electric signal; S4, generate radiomaterial distributed image according to the total electric signal after screening and the position signalling that gathers fluorescence signal.
The detection method of radioactivity photodetector provided by the invention, the some fluorescence signals gathered are produced electric signal through photoelectric effect, and the total electric signal after being sued for peace by electric signal carries out examination denoising, generate radiomaterial distributed image according to by the position signalling of the total electric signal after denoising and collection fluorescence signal.Compared with prior art, the detection method of radioactivity photodetector provided by the invention, first be about to some electric signal summation generate total electric signal, thereafter total electric signal is screened denoising, weak signal in effective removal electric signal, improve the total intensity of output signal simultaneously, improve signal efficient, thus improve the picture quality of the radiomaterial distributed image generated.
Preferably, the some positions gathering fluorescence signal are positioned at same arrangement plane, and described arrangement plane is parallel to the generation plane of described fluorescence signal.
Accompanying drawing explanation
Fig. 1 is the structural representation of existing radioactivity photodetector.
Fig. 2 is the structural representation of radioactivity photodetector of the present invention.
Fig. 3 is the process flow diagram of the detection method of radioactivity photodetector of the present invention.
Fig. 4 is the schematic diagram of the photomultiplier of existing radioactivity photodetector.
Fig. 5 is the schematic diagram of the photomultiplier of radioactivity photodetector of the present invention.
Embodiment
By describing technology contents of the present invention, structural attitude in detail, realized object and effect, accompanying drawing is coordinated to be explained in detail below in conjunction with embodiment.
Figure 1 shows that existing radioactivity photodetector.It is radioactivity photodetector of the present invention described in Fig. 2.Radioactivity photodetector of the present invention comprises signal picker 100 ', photomultiplier (PMT) 200 ', summing circuit 300 ', screening device 400 ' and imaging device 500 '.Identical with the existing radioactivity photodetector shown in Fig. 1: signal picker 100 ' is arranged near internal organs place; Several photomultipliers 200 ' are arranged at the side of signal picker 100 ' away from internal organs, and photomultiplier 200 ' is near signal picker 100 '; Different from existing radioactivity photodetector: the output terminal of several photomultipliers 200 of prior art is electrically connected the input end of a screening device 400 respectively, the output terminal of several screening device 400 is electrically connected summing circuit 300 respectively; The output terminal of several photomultipliers 200 ' of radioactivity photodetector of the present invention is directly electrically connected on summing circuit 300 ', and the output terminal of summing circuit 300 ' is electrically connected a screening device 400 '.The output terminal electrical connection imaging device 500 ' of discriminator circuit 400 '.
More specifically, signal picker 100 ' and several photomultipliers 200 ' are moveable, and the relative position of signal picker 100 ' and several photomultipliers 200 ' is fixed.Time initial, signal picker 100 ' and several photomultipliers 200 ' are positioned at initial position; Body to be detected move to target location and fixing after, signal picker 100 ' and several photomultipliers 200 ' move to the internal organs of signal picker 100 ' near body to be detected, and the both sides of signal picker 100 ' are respectively internal organs and the photomultiplier 200 ' of body to be detected.
Signal picker 100 ' is flat NaI (T1) crystal, and it absorbs the gamma-rays that the radiomaterial in internal organs sends, and produces faint light signal; Several photomultipliers 200 ' arrange in honeycomb fashion matrix, the row plane and several photomultipliers 200 ' are arranged in a row near one end of signal picker 100 ', arrangement plane is parallel to signal picker 100 ', and arrangement plane is just to signal picker 100 '.Several photomultipliers 200 ' gather the fluorescence signal of the varying strength of diverse location respectively, are transformed into the electric signal of several varying strengths through photoelectric effect, and multiple electric signal is sent to summing circuit 300 '.
Several photomultipliers 200 ', summing circuit 300 ', screening device 400 ' and imaging device 500 ' are electrically connected successively.Several electric signal that several photomultipliers 200 ' gather are through summing circuit 300 ', by several electric signal in X-direction or Y-direction summation, total electric signal after summation is outputted to screening device 400 ', total electric signal is screened denoising by screening device 400 ', subsequently, the position signalling of the total electric signal after denoising and photomultiplier 200 ' is sent to imaging device 500 '.Further, imaging device 500 ' comprises D/A converter module (not shown), and the position signalling of the total electric signal after denoising and photomultiplier 200 ' is converted to simulating signal by D/A converter module.
Several electric signal after denoising, before screening device 400 is arranged at summing circuit 300, by several electric signal denoising one by one that photomultiplier 200 exports, are sent to summing circuit 30 ' read group total by existing radioactivity photodetector.Although existing radioactivity photodetector can remove the poor weak signal of signal to noise ratio (S/N ratio), also signal useful for part can be removed simultaneously, reduce output signal, video imaging quality.To this, radioactivity photodetector provided by the invention, after screening device 400 ' is arranged at summing circuit 300 ', several electric signal exported by photomultiplier 200 ' export screening device 400 ' to after summing circuit 300 ' read group total, screening device 400 ' screens denoising to total electric signal, while effectively removing weak signal, strengthen output signal, improve image quality.
Be illustrated in figure 5 the schematic diagram of photomultiplier 200.The center of the arrangement plane of photomultiplier 200 is positioned at: several photomultipliers 200 are just to signal picker 100 for radiomaterial shining point, the fluorescence signal produced due to each photomultiplier 200 and signal picker 100 is apart from different, and the electrical signal intensity that each photomultiplier 200 is produced is different.The numeral indicated in each photomultiplier 200 in diagram is that photomultiplier 200 is different according to light signal strength, the electric signal of the varying strength of generation.In existing radioactivity photodetector, several photomultipliers 200 connect a screening device 400 respectively, and screening device 400 arranges an electric signal and screens threshold values.In the present embodiment, screen threshold values and be set to 200, then the electric signal that the photomultiplier 200 being only arranged in region A gathers is effective, and other electric signal are all removed.
Photomultiplier 200 ' as shown in Figure 4, in radioactivity photodetector of the present invention, several photomultipliers 200 ' are sued for peace through summing circuit 300 ', and the total electric signal after summation enters screening device 400 ' and screens denoising.Further, summing circuit 300 ' screens denoising through screening device 400 ' after the electric signal of X-direction or Y-direction is added summation.In the present embodiment, screen threshold values and can arrange higher value, be set to 400 to screen threshold values, now, the electric signal that the photomultiplier 200 ' being arranged in region B gathers is useful signal.
Shown in composition graphs 2, Fig. 3 and Fig. 5, the detection method of radioactivity photodetector of the present invention is described in detail:
The search coverage of radioactivity photodetector is entered after body picked-up radioactive isotope to be detected enters internal organs; Signal picker 100 ' and several photomultipliers 200 ' are moved to target location from initial position, now, signal picker 100 ' is near the internal organs of body to be detected, and several photomultipliers 200 ' are positioned at the side that signal picker 100 ' deviates from body internal organs to be detected;
The ray that S1, absorption radiating matter send, produces fluorescence signal; Particularly, signal picker 100 ' absorbs the gamma-rays that radioactive isotope sends, and produces fluorescence signal;
S2, gather fluorescence signal respectively in some positions, produce electric signal through photoelectric effect, and some electric signal summations are generated total electric signal; Particularly, several photomultipliers 200 ' arrange in honeycomb fashion matrix, each photomultiplier 200 ' gathers a fluorescence signal and the corresponding position signalling generated residing for this photomultiplier 200 ' respectively, changes the fluorescence signal of collection into electric signal through photoelectric effect; Several electric signal are sued for peace in Y-direction, generates multiple total electric signal;
S3, screen total electric signal; Particularly, discriminator circuit 400 ' arranges one and presets examination threshold values, in the present embodiment, for 400, the electric signal then gathered in B region in Fig. 5 is useful signal, other signals are invalid signals, and effective total electric signal and position signalling by invalid total electric signal shielding zero, and are sent to imaging device 500 ' by discriminator circuit 400 '.
S4, generate radiomaterial distributed image according to the total electric signal after screening and the position signalling that gathers fluorescence signal.Particularly, imaging device 500 ' obtains effective total electric signal and corresponding position signalling, and generates radiomaterial distributed image accordingly.
The schematic diagram of the photomultiplier 200 of the prior art radioactivity photodetector shown in comparison diagram 4, when the examination threshold values of screening device 400 is 200, in diagram, only a-quadrant electric signal is useful signal, and in diagram, useful signal total value is 7300; The schematic diagram of the photomultiplier 200 ' of the radioactivity photodetector of the present invention shown in Fig. 5, the examination threshold values of screening device 400 ' can arrange high value, when examination threshold values is 400, the electric signal of each photomultiplier 200 ' obtains total electric signal in Y-direction summation, total electric signal is deducted after screening threshold values 400, electric signal in B region is useful signal, and in diagram, useful signal is 8300 in a word.Compared to existing technology, signal intensity increases by 13.6% to radioactivity photodetector of the present invention, improves signal efficient, thus improves the picture quality of the radiomaterial distributed image generated.
Above disclosedly be only the preferred embodiments of the present invention, certainly can not limit the interest field of the present invention with this, therefore according to the equivalent variations that the present patent application the scope of the claims is done, still belong to the scope that the present invention is contained.

Claims (5)

1. a radioactivity photodetector, radiomaterial distributed image is generated for the radiating matter detected in internal organs, described radioactivity photodetector comprises signal picker, several photomultipliers, summing circuit and imaging device, and described signal picker is near internal organs; Several photomultipliers are arranged at the side of described signal picker away from internal organs; It is characterized in that, the input end of described summing circuit is directly electrically connected described photomultiplier, and the output terminal of described summing circuit is electrically connected described imaging device; Described radioactivity photodetector also comprises screening device, and the input end of described screening device is electrically connected the output terminal of described summing circuit, and the output terminal of described screening device is electrically connected described imaging device.
2. radioactivity photodetector as claimed in claim 1, it is characterized in that, photomultiplier described in several is arranged in a row near one end of described signal picker row plane, and described arrangement plane is parallel to described signal picker, and described arrangement plane is just to described signal picker.
3. radioactivity photodetector as claimed in claim 2, is characterized in that, photomultiplier described in several is the arrangement of honeycomb fashion matrix.
4. a detection method for radioactivity photodetector, is characterized in that, comprises the following steps:
The ray that S1, absorption radiating matter send, produces fluorescence signal;
S2, gather fluorescence signal respectively in some positions, produce electric signal through photoelectric effect, and some electric signal summations are generated total electric signal;
S3, screen total electric signal;
S4, generate radiomaterial distributed image according to the total electric signal after screening and the position signalling that gathers fluorescence signal.
5. the detection method of radioactivity photodetector as claimed in claim 4, is characterized in that, the some positions gathering fluorescence signal are positioned at same arrangement plane, and described arrangement plane is parallel to the generation plane of described fluorescence signal.
CN201410514932.8A 2014-09-16 2014-09-16 Radioactive photoelectric detector and detection method thereof Pending CN105487099A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109507713A (en) * 2018-11-09 2019-03-22 清华大学 Handheld gamma radiation imaging apparatus and method
CN112426127A (en) * 2020-09-04 2021-03-02 华克医疗科技(北京)股份公司 Robot and method for determining radioactive intensity distribution of target object

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101285715A (en) * 2008-05-06 2008-10-15 中国科学院上海光学精密机械研究所 Weak pulse optical signal detection device and detection method
CN101592623A (en) * 2009-07-06 2009-12-02 中国民航大学 A kind of based on the multi-angle Compton scattering imaging device of screening the class survey device
CN101606846A (en) * 2009-07-10 2009-12-23 中国科学技术大学 PET detector signal treatment facility based on neural network localizer
CN102455431A (en) * 2010-11-25 2012-05-16 上海新漫传感技术研究发展有限公司 Channel type radioactive detector with low detection limit
CN203673073U (en) * 2013-10-29 2014-06-25 深圳市贝斯达医疗器械有限公司 Radioactive photoelectric detector

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101285715A (en) * 2008-05-06 2008-10-15 中国科学院上海光学精密机械研究所 Weak pulse optical signal detection device and detection method
CN101592623A (en) * 2009-07-06 2009-12-02 中国民航大学 A kind of based on the multi-angle Compton scattering imaging device of screening the class survey device
CN101606846A (en) * 2009-07-10 2009-12-23 中国科学技术大学 PET detector signal treatment facility based on neural network localizer
CN102455431A (en) * 2010-11-25 2012-05-16 上海新漫传感技术研究发展有限公司 Channel type radioactive detector with low detection limit
CN203673073U (en) * 2013-10-29 2014-06-25 深圳市贝斯达医疗器械有限公司 Radioactive photoelectric detector

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109507713A (en) * 2018-11-09 2019-03-22 清华大学 Handheld gamma radiation imaging apparatus and method
CN112426127A (en) * 2020-09-04 2021-03-02 华克医疗科技(北京)股份公司 Robot and method for determining radioactive intensity distribution of target object

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Application publication date: 20160413