CN1054522C - Sichuan aconite root analgesic soft extract - Google Patents

Sichuan aconite root analgesic soft extract Download PDF

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Publication number
CN1054522C
CN1054522C CN95117017A CN95117017A CN1054522C CN 1054522 C CN1054522 C CN 1054522C CN 95117017 A CN95117017 A CN 95117017A CN 95117017 A CN95117017 A CN 95117017A CN 1054522 C CN1054522 C CN 1054522C
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medicine
fens
minutes
plaster
root
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Expired - Fee Related
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CN95117017A
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CN1147946A (en
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王永和
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Abstract

The present invention relates to an exterior application ointment prepared from traditional Chinese medicines containing common monkshood mother root, gansui root, ephedra, doubleteeth pubesscent angelica root, rhizoma arisaematis, the carda part of radix angelicae sinensis root, safflower, olibanum, myrrh, suberect spatholobus, dragon blood, clove, etc. as raw materials. The exterior application ointment has the functions of removing cold and dampness, promoting blood circulation to stop pains, smoothening the tendon to activate collateral flow, eliminating swelling and alleviating pain, and is mainly used for treating symptoms, comprising rheumatic arthralgia, pain in the waist and legs, myalgia, etc., and various kinds of arthritis. The clinical test and practice indicate that the ointment has conspicuous curative effect (the effectual rate is 47.3%, and the total effective rate is 92.7%). Compared with the same medicine (for example, the effectual rate of the giraldi daphne ointment is 20%, and the total effective rate is 78%), the exterior application ointment has obvious effect on controlling inflammation and improving the movement of the joint of the vertebral column.

Description

Sichuan aconite root analgesic soft extract
The present invention relates to treat arthralgic Chinese medicine medicine for external use, be specially the externally applied plaster of treatment cold rheumatoid joint pain.
Cold rheumatoid joint pain (abbreviation rheumatic arthralgia) be meant that human feeling's wind-cold damp pathogen causes with joints such as waist, sacrum, hip, lower limb, knee joint, ankle, neck, shoulder, the back of the body, elbow, wrists, myalgia is the disease of main clinical manifestation.Be a kind of commonly encountered diseases, frequently-occurring disease, especially with cold, the humid area sickness rate is higher, a kind of disease that is difficult to cure.Being used for the treatment of the cold rheumatoid joint pain medicine has multiple, usually use more, as with Chinese medicine being the ZHITONG GAO used of all kinds of external application that primary raw material is processed into, plaster etc., the Chinese medicine medicine for external use that wherein is exclusively used in the treatment rheumatic arthralgia is better with the Daphne giraldii Nitsche plaster, but in clinical practice, its curative effect is still not ideal enough.
Purpose of the present invention is on the basis of the external solid preparation of inheriting, excavate the Chinese medicine traditional characteristics, develops a kind of to the better Chinese medicine externally applied plaster preparation of cold rheumatoid joint pain disease therapeuticing effect.
Externally applied plaster is the method that reaches the treatment disease through the skin administration, and skin is made up of for three layers epidermis, corium, subcutaneous tissue, and general medicine all absorbs in the human body from corium easily if can see through epidermis.Because corium has 90% to be euangiotic connective tissue, active blood circulation, the running medicine is very fast, makes medicine promptly arrive lesions position, to reach the purpose of treatment disease.The great advantage of percutaneous drug delivery is to avoid the infringement of medicine to gastrointestinal tract and liver etc., thereby can improve the availability of medicine effectively, obtains better therapeutic effect.Studies show that according to relevant: the reason of cold rheumatoid joint pain is in causing the numbness process, because microcirculation disturbance, local blood microcosmic rheological property is changed, cause morbid substance, the release of inflammatory mediator, cause factors such as body tissue is inflamed, edema, ischemia and cause pathological changes, clinical manifestation is arthralgia, myalgia etc.Based on above-mentioned cognition, the present invention is a foundation with the theoretical basis of the putting into practice of a large amount of treatment arthromyodynias, traditional external therapy, by the treatment observation of routine rheumatism arthromyodynia patient surplus 3000 and the screening of mass efficient Chinese medicine, characteristics at the rheumatism arthromyodynia, have expelling wind and removing dampness, dispersing cold for relieving pain effect in the Chinese prescription of selecting for use, be used for the rheumatism arthromyodynia; The Radix Aconiti etc. that non-immunity and immune inflammation is had obvious suppression effect and an analgesic activity is medicine effectively, is processed into outer plaster type preparation, owing to the synergism of each medicine of prescription, and has than the cold more outstanding effect of existing Drug therapy rheumatism.The medicine of treatment cold rheumatoid joint pain of the present invention is to form A with herbal raw material:
10~50 fens Radix Kansuis of Radix Aconiti 5~20 minutes
25~30 fens Radix Angelicae Pubescentiss of Herba Ephedrae 20~30 minutes
20~30 fens Radix Angelicae Sinensis of Rhizoma Arisaematis 15~30 minutes
15~30 fens Olibanums of Flos Carthami 5~30 minutes
10~30 fens Caulis Spatholobis of Myrrha 25~30 minutes
And Plumbum preparatium is an amount of, forms B:
5~15 fens Flos Caryophyllis of Sanguis Draxonis 5~10 minutes
The external application plaster type preparation (plaster) that Fructus Caryophylli was processed in 5~10 minutes.It is made by the following process steps addition: the Chinese herbal medicine that the said herbal medicine raw material is formed A is placed in the edible vegetable oil with under 220 ℃-235 ℃ the temperature, endures to medicine witheredly, when treating oil to dusky, stops heating, abandons medicinal residues; To fry in advance while hot, and the Plumbum preparatium that sieves, slowly add in the oil, stir, make the abundant mix homogeneously of Plumbum preparatium and oil, the thing of decocting medicinal herbs promptly becomes the pitchy thick paste by the thin pulp shape; In the time of 55 ℃-75 ℃, add the medicine of the composition B that has sieved then, stir; Make poultice, plaster is applied on the plaster of having got ready by every subsides dose 10-15g stand, but the Sichuan aconite root analgesic soft extract of clinical practice is promptly made in doubling while hot.Described edible vegetable oil is meant in Oleum Sesami or the soybean oil any.
During application, with plaster roasting molten after, sticked in the affected part three to five days, general 15 days is a course of treatment.
Sichuan aconite root analgesic soft extract of the present invention has the cold-damp of dispeling the wind, promoting blood circulation and stopping pain, activating muscle and blood, the function of reducing swelling and alleviating pain; Be mainly used in the treatment cold rheumatoid joint pain, lumbago and skelalgia, myalgia etc.; Sichuan aconite root analgesic soft extract is controlling inflammation, and improves aspects such as joint of vertebral column activity and obviously is better than similar medicine Daphne giraldii Nitsche plaster.In clinical trial still is that clinical practice all shows, evident in efficacy (controlled trial: Sichuan aconite root analgesic soft extract: produce effects 47.3%, total effective rate are 92.7% to this plaster in the cold arthralgia of treatment rheumatism; Daphne giraldii Nitsche plaster produce effects 20%, total effective rate are 78%); Also can treat various types of arthritis.Especially at extremely frigid zones, in the above-mentioned disease of treatment, effect is more outstanding.
Embodiment:
Take by weighing Chinese herbal medicine and form A: Radix Aconiti 30g, Radix Kansui 15g, Herba Ephedrae 27g, Radix Angelicae Pubescentis 25g, Rhizoma Arisaematis 25g, Radix Angelicae Sinensis 22g, Flos Carthami 22g, Olibanum 20g, Myrrha 20g, Caulis Spatholobi 27g, form B: Sanguis Draxonis 7.5g, Flos Caryophylli 5g, Fructus Caryophylli 5g,
Above-mentioned prescription A medicine is positioned in the gauze bag, medicated bag is put into the stainless-steel pan that fills soybean oil, endure to medicine witheredly with mild and heavy respiration, the maximum oil temperature is 235 ℃, treats that oil is endured to be dusky, does to drip into the pearl test, promptly in stopping heating, removes medicated bag; Pot from fire, will be fried an amount of Plumbum preparatium good and that sieve while hot, slowly add in the oil, and constantly stir evenly, and incite the cigarette that deoils, Plumbum preparatium is fully mixed with oil, the thing of decocting medicinal herbs promptly becomes the pitchy thick paste by the thin pulp shape in the pot; Get thick paste a little, drip and in water, to treat to cool off slightly the back and take out, with moderate tack-free being advisable of denseness; When treating that thick paste remains on 70 ℃ of left and right sides, slowly add Sanguis Draxonis, Flos Caryophylli and the Fructus Caryophyllis that pass through 200 sieves this moment, stirs, and makes cream drug; At last plaster is coated on the plaster by the even stall with goods spread out on the ground for sale of every subsides 15g, doubling while hot, but promptly make the Sichuan aconite root analgesic soft plaster of clinical practice.

Claims (3)

1. medicine for the treatment of cold rheumatoid joint pain is characterized in that forming A with herbal raw material:
10~50 fens Radix Kansuis of Radix Aconiti 5~20 minutes
25~30 fens Radix Angelicae Pubescentiss of Herba Ephedrae 20~30 minutes
20~30 fens Radix Angelicae Sinensis of Rhizoma Arisaematis 15~30 minutes
15~30 fens Olibanums of Flos Carthami 5~30 minutes
10~30 fens Caulis Spatholobis of Myrrha 25~30 minutes
And Plumbum preparatium is an amount of,
Form B: the external plaster type preparation that 5~10 fens Fructus Caryophyllis of 5~15 fens Flos Caryophyllis of Sanguis Draxonis were processed in 5~10 minutes.
2. the medicine of treatment cold rheumatoid joint pain as claimed in claim 1, it is characterized in that described plaster type preparation is to be placed in the edible vegetable oil by the Chinese herbal medicine that will form A to endure to medicine withered with 220 ℃~235 ℃ temperature, when treating oil, stop heating, abandon medicinal residues to dusky; The Plumbum preparatium that to fry and sieve slowly adds in the oil while hot, fully stirs evenly to be the pitchy thick paste; In the time of 65 ℃~75 ℃, add the composition B medicine that has sieved then, stir evenly; The plaster stand is applied on the plaster, and doubling while hot is processed into.
3. the medicine of treatment cold rheumatoid joint pain as claimed in claim 2 is characterized in that described edible vegetable oil is meant in Oleum Sesami, the soybean oil any.
CN95117017A 1995-10-16 1995-10-16 Sichuan aconite root analgesic soft extract Expired - Fee Related CN1054522C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN95117017A CN1054522C (en) 1995-10-16 1995-10-16 Sichuan aconite root analgesic soft extract

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Application Number Priority Date Filing Date Title
CN95117017A CN1054522C (en) 1995-10-16 1995-10-16 Sichuan aconite root analgesic soft extract

Publications (2)

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CN1147946A CN1147946A (en) 1997-04-23
CN1054522C true CN1054522C (en) 2000-07-19

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CN95117017A Expired - Fee Related CN1054522C (en) 1995-10-16 1995-10-16 Sichuan aconite root analgesic soft extract

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1315508C (en) * 2001-10-09 2007-05-16 张晓松 Borneol toad pain-stopping adhesive plaster and its preparation method
CN109908321A (en) * 2019-04-25 2019-06-21 王明良 A kind of formula of plaster and preparation method thereof
CN111012885A (en) * 2019-12-23 2020-04-17 四川汇智启创科技服务有限公司 External pain relieving plaster and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1076117A (en) * 1993-01-06 1993-09-15 张良华 The production method of tablets for eliminating blood stasis and promoting blood circulation
CN1084748A (en) * 1992-10-29 1994-04-06 单树新 Quick results arthritis dressing and manufacture method thereof
CN1099983A (en) * 1993-09-09 1995-03-15 袁双田 Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1084748A (en) * 1992-10-29 1994-04-06 单树新 Quick results arthritis dressing and manufacture method thereof
CN1076117A (en) * 1993-01-06 1993-09-15 张良华 The production method of tablets for eliminating blood stasis and promoting blood circulation
CN1099983A (en) * 1993-09-09 1995-03-15 袁双田 Medicine for treating rheumatoid or rheumatic arthritis and hyperosteogeny, and method for preparing same

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