CN105435123A - Pharmaceutical composition for treating bedsore - Google Patents
Pharmaceutical composition for treating bedsore Download PDFInfo
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- CN105435123A CN105435123A CN201511011162.6A CN201511011162A CN105435123A CN 105435123 A CN105435123 A CN 105435123A CN 201511011162 A CN201511011162 A CN 201511011162A CN 105435123 A CN105435123 A CN 105435123A
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Abstract
The invention relates to a pharmaceutical composition for treating bedsore. The pharmaceutical composition comprises an oral medicine and an externally applied medicine, wherein the oral medicine is prepared from the following raw materials in parts by weight: 5-8 parts of angelica sinensis, 3-5 parts of poria cocos, 6-9 parts of radix glycyrrhizae, 2-4 parts of flos sophorae and 1-2 parts of rhizoma corydalis decumbentis; the externally applied medicine is prepared from the following raw materials in parts by weight: 5-10 parts of radix zanthoxyli, 2-3 parts of rhizoma wenyujin concisum, 10-15 parts of white peony root, 1-2 parts of seeds of euphorbia lathyris, 5-9 parts of hawthorn leaves, 13-18 parts of tortoise shell, 4-6 parts of amur corktree bark, 6-10 parts of carbonized lotus leaves, 2-3 parts of furnace soil, 6-8 parts of mile swertia herb, 2-3 parts of cortex ailanthi and 1-2 parts of pagodatree pods. The pharmaceutical composition for treating bedsore, provided by the invention is prepared from pure traditional Chinese medicines, the oral medicine and the externally applied medicine are used in a combined manner, and through reasonable combination of the medicines, the pharmaceutical composition is high in safety, high in cure rate for the bedsore and has no side effects on bodies.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of composition of medicine for the treatment of decubital ulcer.
Summary of the invention
Decubital ulcer (having another name called pressure ulcer) be due to nutrition blood for body tissue generation circulatory disorders latter stage result skin decubital ulcer rehabilitation, nurse in be the problem of a universality.About have 60,000 people to die from decubital ulcer complication epidemiological analysis skin decubital ulcer every year according to related documents report to be generally divided three classes: 1. adolescence's neuropath; 2. elderly patient; 3. inpatient.Decubital ulcer produces the necrocytosis in localised region gradually when can be divided into press against soft tissue between skeleton knuckle and long-term stiff dough.Decubital ulcer is the interactional result of many factors, can be divided into the types such as exogenous constitutional, endogenous and Secondary cases.The extrinsic factor mechanical stress resulted from soft tissue comprises compressing, shearing force and friction; Castle's intrinsic factor is decided by the sensitivity of soft tissue exhaustion, comprises malnutrition anemia, incontinence and infection etc.In these pathological factors, most principal element supporting decubital ulcer is oppression inertia.
Its forming process is divided into erythema phase, blister phase and ulcerative stage three phase.The prevention of decubital ulcer is very important, mainly based on intensive care.
Patients with bedsore and misery thereof, often need excision ulcer place skin and flesh to alleviate, extremely difficult recovery.
Summary of the invention
The object of this invention is to provide a kind of composition of medicine for the treatment of decubital ulcer, use Chinese drug preparation, safety non-toxic, removing the necrotic tissue and promoting granulation, has good therapeutic effect to decubital ulcer.
The present invention is achieved through the following technical solutions:
Treat a composition of medicine for decubital ulcer, comprise oral medicine and medicine for external use,
Described oral medicine is made up of the raw material of following weight portion: Radix Angelicae Sinensis 5-8, Poria 3-5, Radix Glycyrrhizae 6-9, Flos Sophorae 2-4, Rhizoma Corydalis Decumbentis 1-2;
Described medicine for external use is made up of the raw material of following weight portion:
Radix Zanthoxyli 5-10, Rhizoma Wenyujin Concisum 2-3, Radix Paeoniae Alba 10-15, Semen Euphorbiae 1-2, Folium Crataegi 5-9, Carapax Et Plastrum Testudinis 13-18, Cortex Phellodendri 4-6, burnt FOLIUM NELUMBINIS 6-10, Terra Flava Usta 2-3, Herba Swertiae Mileensis 6-8, Cortex Ailanthi 2-3, Fructus Sophorae 1-2.
Preferably, described oral medicine is made up of the raw material of following weight portion: Radix Angelicae Sinensis 6, Poria 3.5, Radix Glycyrrhizae 7, Flos Sophorae 3, Rhizoma Corydalis Decumbentis 1.6;
Described medicine for external use is made up of the raw material of following weight portion:
Radix Zanthoxyli 8, Rhizoma Wenyujin Concisum 2.4, the Radix Paeoniae Alba 13, Semen Euphorbiae 1.6, Folium Crataegi 7, Carapax Et Plastrum Testudinis 15, Cortex Phellodendri 5, burnt FOLIUM NELUMBINIS 8, Terra Flava Usta 3, Herba Swertiae Mileensis 6, Cortex Ailanthi 3, the Fructus Sophorae 1.2.
During use, innerlich anwenden directly can decoct and take, and conventional pharmaceutical method also can be used to make other preparations, and adult's use amount (with medicine material dry weight basis) is 35-40g/ days; Medicine for external use uses pharmaceutical methods to make ointment and uses.
Radix Angelicae Sinensis: [property hide with return through] sweet, acrid, warm.Return liver, the heart, spleen channel.[function with cure mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea rheumatic arthralgia, fall and flutter damage and put in order.
Poria: [nature and flavor with return through] are sweet, light is flat.GUIXIN, lung, spleen, kidney channel.[function with cure mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Glycyrrhizae: [nature and flavor with return through] are sweet, flat.GUIXIN, lung, spleen, stomach warp.[function with cure mainly] invigorating the spleen and replenishing QI ， Cheongju thermal detoxification, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Flos Sophorae: [nature and flavor with return through] are bitter, are slightly cold.Return liver, large intestine channel.[function with cure mainly] cooling blood for hemostasis, purging liver-fire.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spit blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.
Rhizoma Corydalis Decumbentis: [nature and flavor with return through] are bitter, micro-pungent, temperature.Return Liver Channel.[function with cure mainly] promoting blood circulation and stopping pain, relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness.For apoplectic hemiplegia, headache, injury from falling down, rheumatic arthralgia, lumbago and skelalgia.
Radix Zanthoxyli: [property hide with return through] is bitter, pungent, flat; Slightly poisonous.Return liver, stomach warp.[function with cure mainly] blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, dispel the wind logical chromium, removing toxic substances and promoting subsidence of swelling; Damage is flutterred, stomachache, toothache, rheumatic arthralgia, venom for order; Externally treating burns and scalds.
Rhizoma Wenyujin Concisum: [nature and flavor with return through] are pungent, bitter, temperature.Return spleen, Liver Channel, [function with cure mainly] removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.For the twinge of the breast side of body, obstruction of qi in the chest and cardialgia, dysmenorrhea amenorrhea ， mass in the abdomen, rheumatism shoulder arm pain, tumbling and swelling.
The Radix Paeoniae Alba: [nature and flavor with return through] are bitter, sour, are slightly cold.Return liver, spleen channel.[function with cure mainly] nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Semen Euphorbiae: [nature and flavor with return through] are pungent, temperature; Poisonous.Return liver, kidney, large intestine channel.[function with cure mainly] removing water retention by purgation, removing blood stasis Xiao Disorder; Tinea erosion wart is treated in external.For constipation and anuresis, edema, phlegm retention, stagnant distension, blood stasis amenorrhea; External treatment stubborn dermatitis, wart.
Folium Crataegi: [nature and flavor with return through] acid is flat.Return Liver Channel.[function with cure mainly] blood circulation promoting and blood stasis dispelling, regulates the flow of vital energy and promotes blood circulation, change turbid blood fat reducing.For qi depression to blood stasis, obstruction of qi in the chest and cardialgia, chest distress, palpitation and amnesia, vertigo and tinnitus, hyperlipemia.
Carapax Et Plastrum Testudinis: [nature and flavor with return through] are salty, sweet, are slightly cold.Return liver, kidney, heart channel.[function with cure mainly] nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, reinforcing the heart of nourishing blood, Gu through only collapsing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, has a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and muscles and bones flaccidity is soft, has a guilty conscience forgetful, and metrorrhagia is through many.
Cortex Phellodendri: [nature and flavor with return through] are bitter, cold, return kidney, urinary bladder channel.[function with cure mainly] heat clearing and damp drying, pathogenic fire purging except steaming, detoxification sore treatment.For damp-heat dysentery, yellow subcutaneous ulcer urine is red, the lower pruritus vulvae of band, and heat is drenched puckery pain, beriberi Wei jiu, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, the eczema sore that wets.
Burnt FOLIUM NELUMBINIS: [nature and flavor with return through] are bitter is flat.Return liver, spleen, stomach warp.[function with cure mainly] clearing away summer-heat and eliminating dampness, astringent therapy removing stasis to stop bleeding.For hemorrhage and puerperal blood faints.
Terra Flava Usta: stop blooding in tune, detumescence of drying.
Herba Swertiae Mileensis: [property hide with return through] is bitter, sweet, cold.Return liver, gallbladder, urinary bladder channel.[function with cure mainly] liver heat removing function of gallbladder promoting, Ning diarrhea of heat type wets.For dampness-heat in the liver and gallbladder, jaundice dark coloured urine, gallbladder-distention hypochondriac pain, the puckery pain of pyretic stranguria.
Cortex Ailanthi: [nature and flavor with return through] are bitter, puckery, cold.Return large intestine, stomach, Liver Channel.[function with cure mainly] heat clearing and damp drying, astringent therapy leukorrhagia stopping, antidiarrheal, hemostasis.For leucorrhea with red and white discharge, damp-heat dysentery, chronic diarrhea chronic dysentery, has blood in stool, metrorrhagia.
The Fructus Sophorae: [nature and flavor with return through] are bitter, cold.Return liver, large intestine channel.[function with cure mainly] clearing away heat-fire, cooling blood for hemostasis.Have blood in stool for intestinal heat, hemorrhoid swell hemorrhage, and liver-heat is had a headache, dizzy conjunctival congestion.
Innerlich anwenden of the present invention, through rational compatibility, has effect of suppressing the hyperactive liver lung heat clearing, heat-clearing and toxic substances removing, relaxing muscles and tendons and activating QI and blood in the collateral, is combined with medicine for external use, can promote the therapeutic effect to decubital ulcer.
Medicine for external use have through compatibility soothing the liverly to expel the heat-evil, promoting the circulation of QI for relieving swelling, cooling blood for hemostasis, removing the necrotic tissue and promoting granulation effect, prevent wound infection simultaneously, promote the absorption to ecchymosis, accelerate wound healing, meanwhile, after compatibility, the toxicity of medicine is eliminated, and improves Drug safety.
Beneficial effect of the present invention: the composition of medicine for the treatment of decubital ulcer provided by the invention, use pure Chinese drug preparation, innerlich anwenden is combined with medicine for external use, and by the reasonable compatibility of medicine, drug safety is high, high to the cure rate of decubital ulcer, has no side effect to health.
Detailed description of the invention
Embodiment 1
Treat a composition of medicine for decubital ulcer, described oral medicine is made up of the raw material of following weight portion: Radix Angelicae Sinensis 6, Poria 3.5, Radix Glycyrrhizae 7, Flos Sophorae 3, Rhizoma Corydalis Decumbentis 1.6;
Described medicine for external use is made up of the raw material of following weight portion:
Radix Zanthoxyli 8, Rhizoma Wenyujin Concisum 2.4, the Radix Paeoniae Alba 13, Semen Euphorbiae 1.6, Folium Crataegi 7, Carapax Et Plastrum Testudinis 15, Cortex Phellodendri 5, burnt FOLIUM NELUMBINIS 8, Terra Flava Usta 3, Herba Swertiae Mileensis 6, Cortex Ailanthi 3, the Fructus Sophorae 1.2.
Embodiment 2
Treat a composition of medicine for decubital ulcer, comprise oral medicine and medicine for external use,
Described oral medicine is made up of the raw material of following weight portion: Radix Angelicae Sinensis 6, Poria 4, Radix Glycyrrhizae 8, Flos Sophorae 3, Rhizoma Corydalis Decumbentis 1.6;
Described medicine for external use is made up of the raw material of following weight portion:
Radix Zanthoxyli 7, Rhizoma Wenyujin Concisum 2.2, the Radix Paeoniae Alba 14, Semen Euphorbiae 1.8, Folium Crataegi 6.8, Carapax Et Plastrum Testudinis 15, Cortex Phellodendri 5, burnt FOLIUM NELUMBINIS 9, Terra Flava Usta 2.5, Herba Swertiae Mileensis 6, Cortex Ailanthi 3, the Fructus Sophorae 1.
Medicine of the present invention is treated for patients with bedsore, patient totally 325, male patient 187, female patient 138, patient age 23-75 year, wherein 22-45 year patient 126,46-65 year patient 138, more than 66 years old patient 61.
Each phase patient numbers is as following table
| First phase decubital ulcer | Second phase decubital ulcer | Third phase decubital ulcer | Fourth phase decubital ulcer | |
| Number | 91 | 150 | 75 | 9 |
Table 1
Therapeutic Method, changes dressings 1 time for every two days, 5 days 1 courses for the treatment of, avoids pungent diet in therapeutic process.
Treatment standard:
Recovery from illness: patient's open sore part blister disappears, without slough and transudate, detumescence, painless, the open sore part forms a scab;
Effective: patients symptomatic obviously alleviates, pain symptom alleviates, and the open sore part is without expansion;
Invalid: patients symptomatic is not improved and even increases the weight of.
Treatment cycle: patient is divided into 3 groups at random, each group indifference opposite sex, 1 course for the treatment of of all first medication of each patient, recovery from illness patient discontinues medication, and the patient that do not fully recover continues medication, treats statistical result after 3 courses for the treatment of.
| Medicament categories | Patient numbers | Healing number | Effective number | Total effective rate |
| Embodiment 1 | 152 | 139 | 12 | 99.3% |
| Embodiment 2 | 108 | 95 | 11 | 98.1% |
| Be used alone the medicine for external use of embodiment 1 | 65 | 36 | 24 | 92.3% |
Table 2
As shown in Table 2, to be used alone medicine for external use cure rate for the cure rate ratio of decubital ulcer high for composition of medicine of the present invention.
Model case
Lin, man, 62 years old, suffer from hemiplegia, long-term bed, right side buttocks forms decubital ulcer, decubital ulcer illing skin is damaged, red and swollen, has slough to exist, open sore part area 2.2*2.5cm, uses 1 course for the treatment of of composition of medicine of the embodiment of the present invention 1, and affected part bleeding disappears, coming off appears in slough, open sore part area reduces, 3 courses for the treatment of of medication, and patient's open sore part forms a scab.
Claims (2)
1. treat a composition of medicine for decubital ulcer, it is characterized in that, comprise oral medicine and medicine for external use,
Described oral medicine is made up of the raw material of following weight portion: Radix Angelicae Sinensis 5-8, Poria 3-5, Radix Glycyrrhizae 6-9, Flos Sophorae 2-4, Rhizoma Corydalis Decumbentis 1-2;
Described medicine for external use is made up of the raw material of following weight portion:
Radix Zanthoxyli 5-10, Rhizoma Wenyujin Concisum 2-3, Radix Paeoniae Alba 10-15, Semen Euphorbiae 1-2, Folium Crataegi 5-9, Carapax Et Plastrum Testudinis 13-18, Cortex Phellodendri 4-6, burnt FOLIUM NELUMBINIS 6-10, Terra Flava Usta 2-3, Herba Swertiae Mileensis 6-8, Cortex Ailanthi 2-3, Fructus Sophorae 1-2.
2. a kind of composition of medicine for the treatment of decubital ulcer according to claim 1, is characterized in that, comprise oral medicine and medicine for external use,
Described oral medicine is made up of the raw material of following weight portion: Radix Angelicae Sinensis 6, Poria 3.5, Radix Glycyrrhizae 7, Flos Sophorae 3, Rhizoma Corydalis Decumbentis 1.6;
Described medicine for external use is made up of the raw material of following weight portion:
Radix Zanthoxyli 8, Rhizoma Wenyujin Concisum 2.4, the Radix Paeoniae Alba 13, Semen Euphorbiae 1.6, Folium Crataegi 7, Carapax Et Plastrum Testudinis 15, Cortex Phellodendri 5, burnt FOLIUM NELUMBINIS 8, Terra Flava Usta 3, Herba Swertiae Mileensis 6, Cortex Ailanthi 3, the Fructus Sophorae 1.2.
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| CN201511011162.6A CN105435123A (en) | 2015-12-30 | 2015-12-30 | Pharmaceutical composition for treating bedsore |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998359A (en) * | 2016-05-25 | 2016-10-12 | 王忠启 | Medicinal powder for treating ulcer |
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| CN101019956A (en) * | 2007-03-19 | 2007-08-22 | 殷彬 | Bedsore treating medicine |
| CN102125634A (en) * | 2011-02-25 | 2011-07-20 | 曹广玲 | Chinese medicinal composition for treating bedsore |
| CN103040900A (en) * | 2013-01-06 | 2013-04-17 | 李媚 | Medicine for treating bedsores |
| CN104225138A (en) * | 2014-09-28 | 2014-12-24 | 夏征梅 | Traditional Chinese medicine for treating bedsore through oral administration and external washing and preparation method of traditional Chinese medicine |
| CN104587206A (en) * | 2015-02-04 | 2015-05-06 | 滨州职业学院 | Medicament for treating bedsore and preparation method of medicament |
| CN104873851A (en) * | 2015-06-04 | 2015-09-02 | 王星月 | Internal and external traditional-Chinese-medicine composition for treating bedsore |
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|---|---|---|---|---|
| CN101019956A (en) * | 2007-03-19 | 2007-08-22 | 殷彬 | Bedsore treating medicine |
| CN102125634A (en) * | 2011-02-25 | 2011-07-20 | 曹广玲 | Chinese medicinal composition for treating bedsore |
| CN103040900A (en) * | 2013-01-06 | 2013-04-17 | 李媚 | Medicine for treating bedsores |
| CN104225138A (en) * | 2014-09-28 | 2014-12-24 | 夏征梅 | Traditional Chinese medicine for treating bedsore through oral administration and external washing and preparation method of traditional Chinese medicine |
| CN104587206A (en) * | 2015-02-04 | 2015-05-06 | 滨州职业学院 | Medicament for treating bedsore and preparation method of medicament |
| CN104873851A (en) * | 2015-06-04 | 2015-09-02 | 王星月 | Internal and external traditional-Chinese-medicine composition for treating bedsore |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105998359A (en) * | 2016-05-25 | 2016-10-12 | 王忠启 | Medicinal powder for treating ulcer |
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Application publication date: 20160330 |