CN105435110A - 一种治疗类风湿性关节炎的药膏贴 - Google Patents
一种治疗类风湿性关节炎的药膏贴 Download PDFInfo
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Abstract
本发明公开了一种治疗类风湿性关节炎的药膏贴,其是由以下重量份配比的中药原料制成的:***子5、荆芥穗5、槐花7、黄连8、广木香15、麻黄5、龙骨10、天南星10、僵蚕7、威灵仙10、姜黄15、黑豆12、乳香12、黄柏15、葛根3、泽泻7、茯苓5、黄芪17、牛膝8、竹茹10、虎杖10、木瓜12、鸡血藤12、皂角刺10、鲜杨树皮8、冬青叶8、五倍子6、白芍10、仙人掌根7、冰片15、土霉素粉3、夏枯草10、槐米12、牡丹皮10、莪术10、栀子7、硼砂5、延胡索6、金樱子根7、大蓟10、鱼腥草15。本发明各原料药经辨证配伍,共奏补肾祛寒、滋阴养血、疏风化湿之功效,由患处直达病灶,标本兼治,达到治愈类风湿性关节炎的目的。
Description
技术领域
本发明涉及一种治疗类风湿性关节炎的外用药膏贴,属于中药领域。
背景技术
类风湿性关节炎的病因至今并不十分明了,目前大多认为其是人体自身免疫性疾病,亦可视为一种慢性的综合征,表现为外周关节的非特异性炎症。此时患病关节及其周围组织呈现进行性破坏,并致使受损关节发生功能障碍。类风湿性关节炎的发病率女性高于男性,女性是男性的2~3倍;欧美国家的发病率明显高于国人。
中药治疗类风湿性关节炎有独特的疗效和优势,由于中药大多数无毒副作用,不良反应小,所以中药治疗类风湿性关节炎越来越受关注。
发明内容
本发明的目的在于提供一种治疗类风湿性关节炎的药膏贴。
本发明所采用的技术解决方案是:
一种治疗类风湿性关节炎的药膏贴,其是由以下重量份配比的中药原料制成的:***子3-12、荆芥穗3-5、槐花5-10、黄连6-12、广木香10-20、麻黄2-10、龙骨6-12、天南星6-13、僵蚕5-10、威灵仙8-15、姜黄10-20、黑豆10-15、乳香10-15、黄柏10-20、葛根3-10、泽泻5-17、茯苓5-10、黄芪6-17、牛膝8-17、竹茹9-19、虎杖7-14、木瓜10-15、鸡血藤10-15、皂角刺10-15、鲜杨树皮8-10、冬青叶6-10、五倍子5-15、白芍6-15、仙人掌根5-10、冰片10-20、土霉素粉2-5、夏枯草8-15、槐米10-15、牡丹皮5-15、莪术8-12、栀子5-12、硼砂3-5、延胡索5-10、金樱子根5-10、大蓟5-15、鱼腥草10-20。
优选的,各中药原料的重量份配比是:***子5、荆芥穗5、槐花7、黄连8、广木香15、麻黄5、龙骨10、天南星10、僵蚕7、威灵仙10、姜黄15、黑豆12、乳香12、黄柏15、葛根3、泽泻7、茯苓5、黄芪17、牛膝8、竹茹10、虎杖10、木瓜12、鸡血藤12、皂角刺10、鲜杨树皮8、冬青叶8、五倍子6、白芍10、仙人掌根7、冰片15、土霉素粉3、夏枯草10、槐米12、牡丹皮10、莪术10、栀子7、硼砂5、延胡索6、金樱子根7、大蓟10、鱼腥草15。
上述治疗类风湿性关节炎的药膏贴,是采取下述步骤制备的:
a将上述重量份的中药原料分别粉碎成100-130目细度,然后混合均匀,得到粉剂;
b将矿物油30份和松香100份注入锅中,文火熔化,放入蜂蜡5-8份,再放入凡士林20份和氧化锌5份,搅拌均匀,然后加入步骤a得到的粉剂50-80份,边加边搅拌,保持文火,最后注入硅氮酮3份搅拌均匀,熬制成膏状;
c摊膏,制成药膏贴。
本发明的药理及效果如下:
类风湿性关节炎属中医学的“痹证”“风寒湿痹证”“风湿热痹证”等范畴。痹证的发生,主要由于正气不足,感受风、寒、湿、热之邪所致。本发明有针对性的选取***子、荆芥穗、槐花、黄连、广木香、麻黄、龙骨、天南星、僵蚕、威灵仙、姜黄、黑豆、乳香、黄柏、葛根、泽泻、茯苓、黄芪、牛膝、竹茹、虎杖、木瓜、鸡血藤、皂角刺、鲜杨树皮、冬青叶、五倍子、白芍、仙人掌根、冰片、土霉素粉、夏枯草、槐米、牡丹皮、莪术、栀子、硼砂、延胡索、金樱子根、大蓟、鱼腥草共41味中药原料制成药膏贴。
其中:***子具有祛风活血,止痛镇静之功效。
荆芥穗性辛,微温,归肺、肝经,有解表散风,透疹的功效。
槐花味苦涩,性寒,具有凉血止血的功效。
黄连属毛茛科、黄连属多年生草本植物,有清热燥湿,泻火解毒之功效。
广木香,健胃消胀、调气解郁、止痛安胎。
麻黄,发汗散寒,宣肺平喘,利水消肿。
龙骨,镇惊安神,敛汗固精,止血涩肠,生肌敛疮。
天南星燥湿化痰。
僵蚕,祛风定惊,化痰散结。
威灵仙,祛风除湿,通络止痛。
姜黄,行气破瘀,通经止痛。
黑豆具有补肾益阴,健脾利湿,除热解毒的功效。
乳香,活血、行气、止痛。
黄柏,清热燥湿、泻火解毒、退热除蒸。
葛根,升阳解肌,透疹止泻,除烦止渴。
泽泻,利水渗湿;泄热通淋。
茯苓,渗湿利水,益脾和胃,宁心安神。
黄芪,补气固表,利尿消肿,托毒排脓,敛疮生肌。
牛膝,补肝肾;强筋骨;活血通经;引火下行;利尿通淋。
竹茹,清热泻火。
虎杖,活血散瘀,清热利湿,解毒,止咳。
木瓜具有平肝舒筋,和胃化湿的功效。
鸡血藤,具有活血补血,调经止痛,舒筋活络之功效。
皂角刺,具有消肿托毒,排脓,杀虫之功效。
鲜杨树皮中含有丰富的杨树皮类脂,其是一种橙黄色脂溶性物质,由于其独有的天然生物学活性,在畜牧兽医、医药方面都有着广泛的应用前景,杨树皮的药用功效最早在《本草纲目》中有记载。
冬青叶又名四季青叶,叶含两种抑菌成分,其中之一是原儿茶酸,另含挥发油、黄酮类,治烫伤,溃疡久不愈合,闭塞性脉管炎,菌痢,外伤出血,冻瘃,皲裂等。
五倍子性寒,味酸、涩,具有敛肺降火、涩肠止泻、敛汗止血、收湿敛疮等功效。
白芍性凉,味苦酸,微寒,具有补血养血、平抑肝阳、柔肝止痛、敛阴止汗等功效。
仙人掌根味苦,性寒,具有行气活血、清热解毒之功效。
冰片具有开窍醒神、散郁火、消肿止痛的功效。
土霉素粉为淡黄色片或糖衣片,属于四环素类,为广谱抑菌剂,具有消炎的功效。
夏枯草味苦、辛,性寒,归肝、胆经。功效清肝泻火、散结化瘀。
槐米性微寒,味苦,具有凉血止血,清肝泻火的功效。
牡丹皮性苦、辛,微寒,具有清热凉血,活血化瘀之功效。
莪术味辛、苦,性温,入肝、脾经。功效行气破血、消积止痛。
栀子味苦,性寒,归心、肝、肺、胃、三焦经。功效泻火除烦、清热利尿、凉血解毒。《本草衍义补遗》:“屈曲下行降火,又能治块中之火”。
硼砂外用具有清热解毒,消肿之功效。
延胡索性辛;苦;温;无毒;具有活血;散瘀;理气;止痛之功效。
金樱子根有收敛固涩,止血敛疮,祛内活血,止痛,杀虫之功效。
大蓟具有凉血止血,祛瘀消肿之功效。
鱼腥草性寒凉,归肺经,具有清热解毒、消肿疗疮、利尿除湿、清热止痢之功效。
全方配伍,共奏补肾祛寒、滋阴养血、疏风化湿之功效,由患处直达病灶,标本兼治,达到治愈类风湿性关节炎的目的,而且疗效好,疗程短,费用低,无毒副作用。
临床资料
1、基本资料:
根据ACR/RULAR2009年最新类风湿性关节炎(RA)诊断标准选择门诊、住院病例150例,按照随机方法,分为治疗组和对照组各75例。两组在病情、性别、年龄、病程等方面经统计学处理差异无显著性。
2、诊断标准:
所有病例均积分在6分以上,符合最新RA诊断标准。
排除标准:
①16岁以下,65岁以上,妊娠、哺乳期妇女。
②合并有乙肝等传染病。
③过敏体质患者。
(凡符合上述任何1项即为排除病例)
3、治疗方法
对照组:甲氨蝶呤片7.5mg/周,来氟米特10mg/日,柳氮磺吡啶肠溶片1.0g/次,每日2次。治疗组在对照组用药基础上加用本发明药膏贴,贴于患处,一日一贴。
4、观察指标和方法
参照《中药新药临床研究指导原则》的标准。显效:主要症状、体征整体改善率≥75%,血沉、CRP正常或明显改善或接近正常;进步:主要症状体征改善率≥50%,血沉、CRP有改善;有效:主要症状、体征整体改善率≥30%,血沉、CRP有改善或无改善;无效:主要症状、体征改善率<30%,血沉、CRP无改善。治疗组(加用本发明药物组)显效46例,进步19例,有效10例,无效0例,显效率61.3%,总有效率100%;对照组显效20例,进步25例,有效21例,无效9例,显效率26.7%,总有效率88%。两组之间差异有非常显著性,治疗组明显优于对照组。
具体实施方式
实施例1
按下述重量份配比称取各中药原料:
***子5、荆芥穗5、槐花7、黄连8、广木香15、麻黄5、龙骨10、天南星10、僵蚕7、威灵仙10、姜黄15、黑豆12、乳香12、黄柏15、葛根3、泽泻7、茯苓5、黄芪17、牛膝8、竹茹10、虎杖10、木瓜12、鸡血藤12、皂角刺10、鲜杨树皮8、冬青叶8、五倍子6、白芍10、仙人掌根7、冰片15、土霉素粉3、夏枯草10、槐米12、牡丹皮10、莪术10、栀子7、硼砂5、延胡索6、金樱子根7、大蓟10、鱼腥草15。
制备步骤如下:
a将上述重量份的中药原料分别粉碎成100-130目细度,然后混合均匀,得到粉剂;
b将矿物油30份和松香100份注入锅中,文火熔化,放入蜂蜡5-8份,再放入凡士林20份和氧化锌5份,搅拌均匀,然后加入步骤a得到的粉剂50-80份,边加边搅拌,保持文火,最后注入硅氮酮3份搅拌均匀,熬制成膏状;
c摊膏,制成药膏贴。
实施例2
按下述重量份配比称取各中药原料:
***子3、荆芥穗5、槐花10、黄连6、广木香10、麻黄10、龙骨6、天南星13、僵蚕5、威灵仙8、姜黄20、黑豆10、乳香10、黄柏20、葛根3、泽泻17、茯苓5、黄芪6、牛膝17、竹茹9、虎杖14、木瓜15、鸡血藤10、皂角刺10、鲜杨树皮10、冬青叶6、五倍子5、白芍15、仙人掌根10、冰片10、土霉素粉2、夏枯草15、槐米10、牡丹皮5、莪术12、栀子5、硼砂5、延胡索5、金樱子根10、大蓟5、鱼腥草10。
按常规方法熬制成药膏贴。
实施例3
按下述重量份配比称取各中药原料:
***子12、荆芥穗3、槐花5、黄连12、广木香20、麻黄2、龙骨12、天南星6、僵蚕10、威灵仙15、姜黄10、黑豆15、乳香15、黄柏10、葛根10、泽泻5、茯苓10、黄芪17、牛膝8、竹茹19、虎杖7、木瓜10、鸡血藤15、皂角刺15、鲜杨树皮8、冬青叶10、五倍子15、白芍6、仙人掌根5、冰片20、土霉素粉5、夏枯草8、槐米15、牡丹皮15、莪术8、栀子12、硼砂3、延胡索10、金樱子根5、大蓟15、鱼腥草20。
制备方法同实施例1。
Claims (3)
1.一种治疗类风湿性关节炎的药膏贴,其特征在于是由以下重量份配比的中药原料制成的:***子3-12、荆芥穗3-5、槐花5-10、黄连6-12、广木香10-20、麻黄2-10、龙骨6-12、天南星6-13、僵蚕5-10、威灵仙8-15、姜黄10-20、黑豆10-15、乳香10-15、黄柏10-20、葛根3-10、泽泻5-17、茯苓5-10、黄芪6-17、牛膝8-17、竹茹9-19、虎杖7-14、木瓜10-15、鸡血藤10-15、皂角刺10-15、鲜杨树皮8-10、冬青叶6-10、五倍子5-15、白芍6-15、仙人掌根5-10、冰片10-20、土霉素粉2-5、夏枯草8-15、槐米10-15、牡丹皮5-15、莪术8-12、栀子5-12、硼砂3-5、延胡索5-10、金樱子根5-10、大蓟5-15、鱼腥草10-20。
2.根据权利要求1所述的一种治疗类风湿性关节炎的药膏贴,其特征在于各中药原料的重量份配比是:***子5、荆芥穗5、槐花7、黄连8、广木香15、麻黄5、龙骨10、天南星10、僵蚕7、威灵仙10、姜黄15、黑豆12、乳香12、黄柏15、葛根3、泽泻7、茯苓5、黄芪17、牛膝8、竹茹10、虎杖10、木瓜12、鸡血藤12、皂角刺10、鲜杨树皮8、冬青叶8、五倍子6、白芍10、仙人掌根7、冰片15、土霉素粉3、夏枯草10、槐米12、牡丹皮10、莪术10、栀子7、硼砂5、延胡索6、金樱子根7、大蓟10、鱼腥草15。
3.如权利要求1或2所述的一种治疗类风湿性关节炎的药膏贴,其特征在于是采取下述步骤制备的:
a将上述重量份的中药原料分别粉碎成100-130目细度,然后混合均匀,得到粉剂;
b将矿物油30份和松香100份注入锅中,文火熔化,放入蜂蜡5-8份,再放入凡士林20份和氧化锌5份,搅拌均匀,然后加入步骤a得到的粉剂50-80份,边加边搅拌,保持文火,最后注入硅氮酮3份搅拌均匀,熬制成膏状;
c摊膏,制成药膏贴。
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104758845A (zh) * | 2015-04-20 | 2015-07-08 | 张先雷 | 一种治疗肩关节周围炎的外用中药膏 |
CN104784405A (zh) * | 2015-05-04 | 2015-07-22 | 张先雷 | 一种用于治疗耳石症的药膏贴 |
CN105148196A (zh) * | 2015-10-08 | 2015-12-16 | 万健 | 一种治疗类风湿性关节炎的中药制剂 |
CN105169294A (zh) * | 2015-11-02 | 2015-12-23 | 王丽云 | 一种治疗肩关节周围炎的中药膏剂 |
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CN104784405A (zh) * | 2015-05-04 | 2015-07-22 | 张先雷 | 一种用于治疗耳石症的药膏贴 |
CN105148196A (zh) * | 2015-10-08 | 2015-12-16 | 万健 | 一种治疗类风湿性关节炎的中药制剂 |
CN105169294A (zh) * | 2015-11-02 | 2015-12-23 | 王丽云 | 一种治疗肩关节周围炎的中药膏剂 |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106333999A (zh) * | 2016-11-05 | 2017-01-18 | 王俊卿 | 一种治疗腰、腿、关节等各部位不适的药物 |
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