CN105412306A - Traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of yang deficiency and qi depression, and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of yang deficiency and qi depression, and preparation method thereof Download PDFInfo
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- CN105412306A CN105412306A CN201510934449.XA CN201510934449A CN105412306A CN 105412306 A CN105412306 A CN 105412306A CN 201510934449 A CN201510934449 A CN 201510934449A CN 105412306 A CN105412306 A CN 105412306A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention relates to a traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of yang deficiency and qi depression. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5-15 parts of blumea balsamifera, 3-6 parts of anisum stellatum, 3-6 parts of pternopetalum vulgare, 3-9 parts of ramulus cinnamomi, 15-25 parts of radix codonopsis, 30-40 parts of herba lysimachiae, 10-20 parts of herba artemisiae scopariae, 3-9 parts of radix gentianae macrophyllae, 3-9 parts of fructus akebiae, 3-9 parts of tangerine peel, 3-9 parts of exocarpium citri grandis, 3-9 parts of fructus aurantii immaturus and 3-9 parts of glycyrrhiza glabra. The traditional Chinese medicine composition has pertinence for chronic cholecystitis with syndrome of yang deficiency and qi depression based on the theory of traditional Chinese medicine and the main therapeutic principle of warming yang and benefiting qi, dispersing stagnated liver qi for promoting bile flow and regulating qi; the thirteen drugs in the composition coordinate with each other, so as to achieve the effect of treating chronic cholecystitis with syndrome of yang deficiency and qi depression; the traditional Chinese medicine composition takes the pure traditional Chinese medicines as the raw materials, and has little toxic and side effect and high pertinence.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, particularly one treats yang deficiency stasis type chronic cholecystitis Chinese medicine composition and preparation method thereof.
Background technology
Chronic cholecystitis is modal a kind of gallbladder disease, and patient generally has cholelithiasis simultaneously, but sees China is quite a few without the chronic cholecystitis patient of calculus.Chronic cholecystitis can be the sequela of acute cholecystitis sometimes, but Most patients did not suffer from acute cholecystitis in the past, due to gallbladder persistent inflammatory, fiber can be there is and thicken in gallbladder wall, cicatricial contraction, causes atrophy of gallbladder, and blister cavities can be completely closed, cause gallbladder function to go down, even completely lose function.The clinical manifestation of chronic cholecystitis is not true to type more, also not obvious.Often may have right upper quadrant of the abdomen dull pain, bitter taste, abdominal distention, belch at ordinary times, feel sick and the indigestion symptom such as anorexia greasy food, under some patients then feel right omoplate, right season rib or place's dull pain such as right waist.Standing, to move and more obvious after psychrolusia.Have mild tenderness under patient's upper right abdominal rib edge, or pressure there is sense of discomfort.Chronic cholecystitis Chinese medicine is referred to as gallbladder-distention disease.Gallbladder-distention refers to that gallbladder internal organs mechanism of qi leads to a kind of disease being main clinical manifestation with right flank distending pain of falling and lacking of proper care and causing.Gallbladder-distention is sick first appeared in "Nei Jing".The sick position of primary disease is at gallbladder, in close relations with liver (spleen) stomach.Characteristic of disease have deficiency and excess point, excess syndrome has that QI depression of the liver and gallbladder, qi depression to blood stasis, gallbladder internal organs are hot and suffocating, dampness-heat in the liver and gallbladder.Deficiency syndrome have deficiency of YIN stasis, yang deficiency stasis.
At present, although have much for the Chinese medicine of chronic cholecystitis, because its specific aim is poor, different to different sufferer effects.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, provide one to treat yang deficiency stasis type chronic cholecystitis Chinese medicine composition and preparation method thereof.
Technical scheme of the present invention is:
One treats yang deficiency stasis type chronic cholecystitis Chinese medicine composition, is prepared from according to parts by weight by following component:
Herba Blumeae Balsamiferae 5-15 part, Fructus Anisi Stellati 3-6 part, the husky 3-6 part of Zijin, Ramulus Cinnamomi 3-9 part, Radix Codonopsis 15-25 part, Herba Lysimachiae 30-40 part, Herba Artemisiae Scopariae 10-20 part, Radix Gentianae Macrophyllae 3-9 part, Fructus Akebiae 3-9 part, Pericarpium Citri Reticulatae 3-9 part, Exocarpium Citri Grandis 3-9 part, Fructus Aurantii Immaturus 3-9 part, Radix Glycyrrhizae 3-9 part.
On the basis of such scheme, one treats yang deficiency stasis type chronic cholecystitis Chinese medicine composition, is prepared from according to parts by weight by following component:
Herba Blumeae Balsamiferae 10 parts, Fructus Anisi Stellati 4 parts, husky 5 parts of Zijin, Ramulus Cinnamomi 6 parts, Radix Codonopsis 20 parts, Herba Lysimachiae 35 parts, Herba Artemisiae Scopariae 15 parts, Radix Gentianae Macrophyllae 6 parts, Fructus Akebiae 6 parts, Pericarpium Citri Reticulatae 6 parts, Exocarpium Citri Grandis 6 parts, Fructus Aurantii Immaturus 6 parts, 6 parts, Radix Glycyrrhizae.
Prepare a method for treatment yang deficiency stasis type chronic cholecystitis Chinese medicine composition as above, concrete steps are as follows:
(1) take each component in compositions according to quantity, soak 2 hours in the cold water of 8-10 times amount;
(2) intense fire changes slow fire and continues to boil 30 minutes after boiling;
(3) filter, discard filtering residue.
The present invention, based on theory of Chinese medical science, for yang deficiency stasis type chronic cholecystitis, with warming YANG and invigorating QI, depressed liver-energy dispersing and function of gallbladder promoting, regulates the flow of vital energy as the main rule for the treatment of, in compositions, and Herba Blumeae Balsamiferae: warming middle-JIAO, expelling wind and removing dampness; Fructus Anisi Stellati: warming YANG, cold expelling, to regulate the flow of vital energy; Zijin is husky: cold expelling, regulate the flow of vital energy, pain relieving; Ramulus Cinnamomi: warming spleen and stomach for dispelling cold, temperature logical breast sun, warming the meridian and promoting blood circulation, activating YANG for promoting diuresis; Radix Codonopsis: invigorating the spleen and replenishing QI, promote the production of body fluid and nourish blood; Five medicines are monarch drug altogether; Herba Lysimachiae: dehumidifying jaundice eliminating, relieving stranguria by diuresis, removing toxic substances and promoting subsidence of swelling; Herba Artemisiae Scopariae: jaundice eliminating subcutaneous ulcer, heat clearing and damp drying; Radix Gentianae Macrophyllae: wind-damp dispelling, clearing away damp-heat, stopping numbness pain, reducing the asthenic fever; Fructus Akebiae: liver-smoothing, qi-regulating, invigorates blood circulation, eliminating stasis to stop pain, relieving restlessness diuresis; Four medicines are ministerial drug altogether; Pericarpium Citri Reticulatae: regulate the flow of vital energy adjust in, drying dampness to eliminate phlegm; Exocarpium Citri Grandis: regulating the flow of QI to ease the stomach, drying dampness to eliminate phlegm; Fructus Aurantii Immaturus: soothing the liver row is stagnant, hill start eliminating stagnation, ascending up spleen-Qi and Yang; Three medicines are adjuvant drug; Radix Glycyrrhizae: invigorating the spleen and replenishing QI, relieving spasm to stop pain, the mitigation property of medicine; For making medicine.13 herbal medicines cooperatively interact, and reach the effect for the treatment of yang deficiency stasis type chronic cholecystitis, the present invention is with pure Chinese medicine for raw material, and toxic and side effects is little, with strong points.
Detailed description of the invention
The specific embodiment of the present invention is as follows:
Embodiment 1:
One treats yang deficiency stasis type chronic cholecystitis Chinese medicine composition, is prepared from according to weight by following component:
Herba Blumeae Balsamiferae 5g, Fructus Anisi Stellati 3g, Zijin husky 3g, Ramulus Cinnamomi 3g, Radix Codonopsis 15g, Herba Lysimachiae 30g, Herba Artemisiae Scopariae 10g, Radix Gentianae Macrophyllae 3g, Fructus Akebiae 3g, Pericarpium Citri Reticulatae 3g, Exocarpium Citri Grandis 3g, Fructus Aurantii Immaturus 3g, Radix Glycyrrhizae 3g.
Preparation method concrete steps are as follows:
(1) take each component in compositions according to quantity, soak 2 hours in the cold water of 8-10 times amount;
(2) intense fire changes slow fire and continues to boil 30 minutes after boiling;
(3) filter, discard filtering residue.
Embodiment 2:
One treats yang deficiency stasis type chronic cholecystitis Chinese medicine composition, is prepared from according to weight by following component:
Herba Blumeae Balsamiferae 10g, Fructus Anisi Stellati 4g, Zijin husky 5g, Ramulus Cinnamomi 6g, Radix Codonopsis 20g, Herba Lysimachiae 35g, Herba Artemisiae Scopariae 15g, Radix Gentianae Macrophyllae 6g, Fructus Akebiae 6g, Pericarpium Citri Reticulatae 6g, Exocarpium Citri Grandis 6g, Fructus Aurantii Immaturus 6g, Radix Glycyrrhizae 6g.
Preparation method concrete steps are as follows:
(1) take each component in compositions according to quantity, soak 2 hours in the cold water of 8-10 times amount;
(2) intense fire changes slow fire and continues to boil 30 minutes after boiling;
(3) filter, discard filtering residue.
Embodiment 3:
One treats yang deficiency stasis type chronic cholecystitis Chinese medicine composition, is prepared from according to weight by following component:
Herba Blumeae Balsamiferae 15g, Fructus Anisi Stellati 6g, Zijin husky 6g, Ramulus Cinnamomi 9g, Radix Codonopsis 25g, Herba Lysimachiae 40g, Herba Artemisiae Scopariae 20g, Radix Gentianae Macrophyllae 9g, Fructus Akebiae 9g, Pericarpium Citri Reticulatae 9g, Exocarpium Citri Grandis 9g, Fructus Aurantii Immaturus 9g, Radix Glycyrrhizae 9g.
Preparation method concrete steps are as follows:
(1) take each component in compositions according to quantity, soak 2 hours in the cold water of 8-10 times amount;
(2) intense fire changes slow fire and continues to boil 30 minutes after boiling;
(3) filter, discard filtering residue.
Medicine of the present invention was in 2004 to 2012 the routine patients of clinical observation yang deficiency stasis type chronic cholecystitis 25, and clinical report is as follows:
1, physical data
In 25 routine patients, in age 24-64 year, the course of disease is many at 5 months to 6 years, 54 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that 2.1 diagnosis basis State Administration of Traditional Chinese Medicines issue: 1. persistence upper right abdomen dull pain or sense of discomfort, or Ban You omoplate district pain; 2. the indigestion symptoms such as nauseating, belch, acid regurgitation, abdominal distention and scorching hot are had, the postemphasis of feed greasy food; 3. the course of disease is long, and the state of an illness has acute attack and alleviates feature alternately; 4. gallbladder area is carved with mild tenderness and is kowtowed pain; 5. in bile, mucus increases, and leukocyte is in heaps, positive bacterial culture; 6. the visible cholelithiasis of ultrasound diagnosis, thickening of capsule wall of gallbladder, gallbladder reduces or is out of shape; 7. the visible cholelithiasis of cholecystography, gallbladder reduces or is out of shape, and gallbladder contraction function is bad, or gallbladder development is thin.Yang deficiency stasis type chronic cholecystitis disease: the indistinct distending pain of right flank, time when doing only, distension and fullness in the abdomen, vomit clear saliva, aversion to cold and cold limbs, Mental fatigue is breathed hard, weak asthenia, and pale tongue with white fur is greasy, and stringy pulse is weak unable.
2.2 exclusion standards:
1. the age is under-18s or over-65s person; 2. acute gangrenous cholecystitis, the suppurative cholecystitis of acute obstruction, perforation of gallbladder peritonitis person; 3. gestation or women breast-feeding their children, be associated with severe primary disease, the psychotics such as cardiovascular, liver, kidney and hemopoietic system.
3, Therapeutic Method
According to medicine prepared by the invention process 2, every day 1 dose, taking at twice, 10 days was 1 course for the treatment of, treated 5 courses for the treatment of continuously.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Recovery from illness: the primary and secondary syndrome of this syndrome disappears, ultrasound diagnosis gallbladder wall and contractile function recover normal, and gallbladder district pain disappears, and diet, digestion recover normal.Drug withdrawal 3 months is unchanged, follows up a case by regular visits to half a year more than without recurrence;
Take a turn for the better: the improvement of this syndrome primary and secondary syndrome accounts for more than half, and ultrasound diagnosis gallbladder wall and contractile function have clear improvement, and gallbladder district tenderness is clearly better, diet, digestion are clearly better;
Invalid: through treatment symptom without alleviation, ultrasound diagnosis gallbladder wall and contractile function are without significant change, and every symptom is not improved.
4.2 results:
After 5 course of therapy, the therapeutic outcome of 25 routine patients is as follows:
Recovery from illness 19 example, take a turn for the better 5 examples, invalid 1 example.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (3)
1. treat a yang deficiency stasis type chronic cholecystitis Chinese medicine composition, it is characterized in that, be prepared from according to parts by weight by following component:
Herba Blumeae Balsamiferae 5-15 part, Fructus Anisi Stellati 3-6 part, the husky 3-6 part of Zijin, Ramulus Cinnamomi 3-9 part, Radix Codonopsis 15-25 part, Herba Lysimachiae 30-40 part, Herba Artemisiae Scopariae 10-20 part, Radix Gentianae Macrophyllae 3-9 part, Fructus Akebiae 3-9 part, Pericarpium Citri Reticulatae 3-9 part, Exocarpium Citri Grandis 3-9 part, Fructus Aurantii Immaturus 3-9 part, Radix Glycyrrhizae 3-9 part.
2. treatment yang deficiency stasis type chronic cholecystitis Chinese medicine composition according to claim 2, is characterized in that, be prepared from by following component according to parts by weight:
Herba Blumeae Balsamiferae 10 parts, Fructus Anisi Stellati 4 parts, husky 5 parts of Zijin, Ramulus Cinnamomi 6 parts, Radix Codonopsis 20 parts, Herba Lysimachiae 35 parts, Herba Artemisiae Scopariae 15 parts, Radix Gentianae Macrophyllae 6 parts, Fructus Akebiae 6 parts, Pericarpium Citri Reticulatae 6 parts, Exocarpium Citri Grandis 6 parts, Fructus Aurantii Immaturus 6 parts, 6 parts, Radix Glycyrrhizae.
3. a preparation method for treatment yang deficiency stasis type chronic cholecystitis Chinese medicine composition according to claim 1 and 2, it is characterized in that, concrete steps are as follows:
(1) take each component in compositions according to quantity, soak 2 hours in the cold water of 8-10 times amount;
(2) intense fire changes slow fire and continues to boil 30 minutes after boiling;
(3) filter, discard filtering residue.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510934449.XA CN105412306A (en) | 2015-12-15 | 2015-12-15 | Traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of yang deficiency and qi depression, and preparation method thereof |
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| CN201510934449.XA CN105412306A (en) | 2015-12-15 | 2015-12-15 | Traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of yang deficiency and qi depression, and preparation method thereof |
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| CN105412306A true CN105412306A (en) | 2016-03-23 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111886293A (en) * | 2018-03-28 | 2020-11-03 | 太阳油墨制造株式会社 | Curable resin composition, dry film, cured product, and electronic component |
-
2015
- 2015-12-15 CN CN201510934449.XA patent/CN105412306A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 李七一: "《中医老年病学》", 30 September 2009, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111886293A (en) * | 2018-03-28 | 2020-11-03 | 太阳油墨制造株式会社 | Curable resin composition, dry film, cured product, and electronic component |
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