CN105394502A - Health beverage for treating allergic rhinitis - Google Patents
Health beverage for treating allergic rhinitis Download PDFInfo
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- CN105394502A CN105394502A CN201510714455.4A CN201510714455A CN105394502A CN 105394502 A CN105394502 A CN 105394502A CN 201510714455 A CN201510714455 A CN 201510714455A CN 105394502 A CN105394502 A CN 105394502A
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- 206010039085 Rhinitis allergic Diseases 0.000 title claims abstract description 26
- 201000010105 allergic rhinitis Diseases 0.000 title claims abstract description 26
- 235000013361 beverage Nutrition 0.000 title claims abstract description 22
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- 238000000855 fermentation Methods 0.000 claims abstract description 30
- 230000004151 fermentation Effects 0.000 claims abstract description 30
- 239000002002 slurry Substances 0.000 claims abstract description 27
- 238000002156 mixing Methods 0.000 claims abstract description 26
- 238000003756 stirring Methods 0.000 claims abstract description 24
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims abstract description 14
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 claims abstract description 14
- 235000008384 feverfew Nutrition 0.000 claims abstract description 14
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- 239000000284 extract Substances 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 33
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- 229940001448 feverfew extract Drugs 0.000 claims description 17
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- LLQHSBBZNDXTIV-UHFFFAOYSA-N 6-[5-[[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]methyl]-4,5-dihydro-1,2-oxazol-3-yl]-3H-1,3-benzoxazol-2-one Chemical group C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)CC1CC(=NO1)C1=CC2=C(NC(O2)=O)C=C1 LLQHSBBZNDXTIV-UHFFFAOYSA-N 0.000 description 1
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- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
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- DEDOPGXGGQYYMW-UHFFFAOYSA-N molinate Chemical compound CCSC(=O)N1CCCCCC1 DEDOPGXGGQYYMW-UHFFFAOYSA-N 0.000 description 1
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- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
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- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
- A23L2/382—Other non-alcoholic beverages fermented
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses health beverage for treating allergic rhinitis. The health beverage is prepared by the following steps: preparing common nostoc fermented slurry; preparing a violet magnolia extracting solution; preparing rose and feverfew extracting solutions; uniformly mixing and stirring 3 to 4 parts of common nostoc fermented slurry, 1 to 1.5 parts of the violet magnolia extracting solution, 3 parts of the rose and feverfew extracting solutions, 5 parts of sugar and 22 to 25 parts of water, and performing homogenization, thus obtaining a mixed solution, wherein the health beverage is canned under a vacuum and germfree environment and stored under normal temperature. The health beverage disclosed by the invention is prepared by a special common nostoc fermentation technology, so that the health beverage tastes delicious, is good in treating effect, does not have side effects, and is good in allergic rhinitis treating effect, and allergic rhinitis is difficult to recur.
Description
Technical field
The invention belongs to technical field of health-care, be specifically related to a kind of health beverages for the treatment of of allergic rhinitis.
Background technology
Allergic rhinitis (allergicrhinitis) is also known as allergic rhinitis, that the medium (mainly histamine) mediated by IgE after atopic individuals contact sensibiligen discharges and has the schneiderian membrance chronic inflammatory reaction disease that panimmunity competent cell and cell factor etc. participate in, with rhiocnesmus, sneeze, nose hypersecretion, schneiderian membrance swelling etc. for main feature.This disease is clinical is often divided into perennial allergic rhinitis and pollinosis, and the latter is also called " pollinosis ".Although allergic rhinitis are not a kind of serious diseases, but the daily life of patient, study and operating efficiency can be affected, and cause heavy burden economically, bronchial astehma, nasosinusitis, nasal polyp, tympanitis etc. can be brought out, or occur with allergic conjunctivitis simultaneously.
The visible schneiderian membrance of rhinoscopy can be pale, greyish white or light blue, two concha nasalis inferior oedema, visible clear tears or sticky tears at the bottom of meatus nasi communis and nasal cavity.As concurrent infection, then mucous membrane is congested, and bilateral concha nasalis inferior is dark red, and secretion is in glutinous purulence or purulence.The visible concha nasalis media Polypoid changes of medical history elder, hypertrophic inferior turbinate or middle nasal meatus polyp.
Traditional by the low dose of antigen of hypodermic injection and the immunization therapy progressively increasing concentration has applied nearly 100 years.About the machine-processed theory of this therapy is a lot, but the specific IgE blocking antibody that current Most scholars and allergy worker agree with blocking-up allergen to be combined with IgE more is theoretical.Although immunization therapy alleviates clinical symptoms to the patient of 60% ~ 90%, but its side effect is as the generation of anaphylactoid reaction, the even death of a few patients, and the longer course for the treatment of (general needs 2 years or longer time), limit it in clinical application.
The health beverages that the special zymotechnique of nostoc that the present invention aims to provide a kind for the treatment of of allergic rhinitis is made, its mouthfeel is good, and result for the treatment of is good, without any side effects.
Summary of the invention
The invention provides a kind of health beverages for the treatment of of allergic rhinitis, its mouthfeel is good, and result for the treatment of is good, without any side effects.
Nostoc, be commonly called as water auricularia auriculajudae, have another name called Azotica, ancient title beauty tea is a kind of natural algae product, containing abundant algae starch, protein, there are 7 seed amino acids in necessary 8 seed amino acids of human body, also be rich in active polysaccharide, multivitamin, phycobilin and carotenoid etc. simultaneously, nutritious, not only can keep fit also to have effect of health care.
Rose is containing abundant vitamin A, C, B, E, K, and tannic acid, can improve endocrinopathy, to dispelling fatigue and wound healing also helpful.Regulating the qi flowing in the channels blood, conditioning female pathology problem, stimulates circulation, beauty treatment, menstruation regulating, and diuresis, relaxes stomach neural, anti-wrinkle, anti-frostbite, skin maintenance.
The flower bud of lily magnolia is the bud of the Magnoliacea plant flower bud of lily magnolia or yulan.Warm in nature, the pungent micro-hardship of taste.Dispersing wind and cold, clearing the nasal passage.For anemofrigid headache, nasal obstruction, nasosinusitis, turbid nasal discharge.
Feverfew (WhiteChrysanthemum) composite family, herbaceos perennial.Originate in central China, east, southwest extensively to cultivate as famous ornamental plant.Have another name called camomile, Hang Ju, FLOS CHRYSANTHEMI ALBA from Haizhou of China, tea chrysanthemum, medicine chrysanthemum.Feverfew includes chrysanthemum glucoside, amino acid, flavonoids and multivitamin and trace element, and Chinese medical research shows, feverfew has nourishing the liver to improve visual acuity, clears away heart-fire, kidney tonifying, strengthening the spleen and stomach, wet one's whistle, promote the production of body fluid, and the effect such as adjustment blood fat.
Key inventive of the present invention is selected and is to carry out special fermentation process to nostoc, and it contains the compositions such as multiple beneficial bacterium and polysaccharide, and other plant is composite, under the prerequisite had no side effect, effectively can alleviate allergic rhinitis.Its mouthfeel is good, and drink conveniently, raw material is simply controlled, has the effect of very good alleviation allergic rhinitis.
Technical scheme of the present invention is as follows:
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stir, constant temperature 35 DEG C process 10-15min, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, at 38 DEG C of bottom fermentation 36-42 hour, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 50-60 part water boil, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 15-16 part feverfew, keeps 40min after adding 50 parts of water boils, both obtains plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 3-4 part nostoc fermentation slurry, 1-1.5 part flower bud of lily magnolia extract, 3 portions of roses, feverfew extract, 5 parts of sugar, 22-25 part water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
Usefulness of the present invention is:
1. the present invention carries out special fermentation process to nostoc, then with the flower bud of lily magnolia, and rose, feverfew is composite makes compound beverage, and its mouthfeel is good, and drink conveniently, raw material is simply controlled;
2. drink of the present invention has very good treatment of allergic rhinitis, relief of symptoms, the effect not easily recurred;
3. beverage of the present invention also find that there is beautifying face and moistering lotion, nourishing Yin and moistening lung, regulate endocrine effect.
Detailed description of the invention
The present invention's papain used is refining papain, and vigor is 200,000 u/g(i.e. 200,000 units).
embodiment 1:
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stir, constant temperature 35 DEG C process 10min, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, 38 DEG C of bottom fermentations 42 hours, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 50 parts of water boils, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 16 portions of feverfews, keep 40min after adding 50 parts of water boils, both obtain plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 3 parts of nostoc fermentation slurries, 1 portion of flower bud of lily magnolia extract, 3 portions of roses, feverfew extract, 5 parts of sugar, 25 parts of water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
embodiment 2:
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stir, constant temperature 35 DEG C process 15min, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, 38 DEG C of bottom fermentations 36 hours, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 60 parts of water boils, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 15 portions of feverfews, keep 40min after adding 50 parts of water boils, both obtain plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 4 parts of nostoc fermentation slurries, 1.5 portions of flower bud of lily magnolia extracts, 3 portions of roses, feverfew extract, 5 parts of sugar, 22 parts of water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
embodiment 3:
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stir, constant temperature 35 DEG C process 11min, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, 38 DEG C of bottom fermentations 41 hours, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 55 parts of water boils, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 16 portions of feverfews, keep 40min after adding 50 parts of water boils, both obtain plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 3 parts of nostoc fermentation slurries, 1.1 portions of flower bud of lily magnolia extracts, 3 portions of roses, feverfew extract, 5 parts of sugar, 24 parts of water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
embodiment 4:
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stir, constant temperature 35 DEG C process 14min, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, 38 DEG C of bottom fermentations 37 hours, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 59 parts of water boils, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 15 portions of feverfews, keep 40min after adding 50 parts of water boils, both obtain plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 4 parts of nostoc fermentation slurries, 1.4 portions of flower bud of lily magnolia extracts, 3 portions of roses, feverfew extract, 5 parts of sugar, 23 parts of water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
embodiment 5:
Comparative example 1, nostoc does not add papain pretreatment.
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, 38 DEG C of bottom fermentations 40 hours, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 51 parts of water boils, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 16 portions of feverfews, keep 40min after adding 50 parts of water boils, both obtain plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 3 parts of nostoc fermentation slurries, 1.2 portions of flower bud of lily magnolia extracts, 3 portions of roses, feverfew extract, 5 parts of sugar, 25 parts of water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
embodiment 6:
Comparative example 2, nostoc does not ferment, and directly pulls an oar.
A health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stirs, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 58 parts of water boils, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 15 portions of feverfews, keep 40min after adding 50 parts of water boils, both obtain plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By 4 parts of nostoc fermentation slurries, 1.3 portions of flower bud of lily magnolia extracts, 3 portions of roses, feverfew extract, 5 parts of sugar, 22 parts of water, stir after mixing, mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
embodiment 7:
Get 160 BALB/c mouses and be divided into 7 groups at random, adopt OVA lumbar injection and nose to excite and sets up mouse AR model, wherein 1 group as positive control, 1 group as negative control, the drink of all the other groups embodiment 1-6 carries out gavage, each 1ml, once a day, 42 days are amounted to; The positive and negative control group are with physiological saline gavage.Within 42nd day, put to death mouse, H-E dyeing is carried out to mouse nasal tissue, count and compare the infiltration degree of nasal mucosa EC.
Result shows: at the 42nd day, the EC of 4 groups of mouse of embodiment 1-4 infiltrated number and all obviously reduces compared with positive controls, and especially EC's number of the infiltration of embodiment 1 group is almost identical with negative control group.And EC's number of the infiltration of comparative example 5-6 group only reduces slightly than positive controls.
As can be seen here, key of the present invention is unique nostoc fermentation technique, the process of a period of time is first carried out with papain, then the fermentation of certain hour is carried out with special bacterial strain, significant synergy is had between this 2 step, as can be seen from experimental data, omit Papain ferment treatment or strain fermentation process, the effect of the treatment of allergic rhinitis all do not possessed.
embodiment 8:
The formula of the embodiment of the present invention 1 is prepared into finished product, carry out expansion experiment, choose 100 ages 20-50 year between, suffer from the patient of allergic rhinitis, the ill time limit is all between 1-3, drink drink of the present invention to described volunteer, every day 2 times, each 200ml, record is followed up a case by regular visits to after 1 month, feedback is cured or effective volunteer, stops drinking 30 days, continues record recurrence.
Result shows, and 95 patients all reach healing, and remaining 5 also have significant remission effect, and cure rate is up to 95%.Stop using after 30 days, only have a patient to represent and recur to some extent.
In addition, some volunteer also reacts, beverage of the present invention also find that there is beautifying face and moistering lotion, nourishing Yin and moistening lung, regulate endocrine effect.
The above; be only the present invention's preferably detailed description of the invention; but protection scope of the present invention is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; be equal to according to technical scheme of the present invention and inventive concept thereof and replace or change, all should be encompassed within protection scope of the present invention.
Claims (2)
1. a health beverages for treatment of allergic rhinitis, it is prepared from by the following method:
(1) nostoc fermentation slurry is prepared:
Select complete high-quality nostoc, clean by clean water, the water adding 10 times is pulled an oar, and is processed into slurries, then adds the papain of 0.05 times of nostoc quality, stir, constant temperature 35 DEG C process 10-15min, according to the ratio access probio of inoculum concentration 0.2%, after stirring gently, at 38 DEG C of bottom fermentation 36-42 hour, for subsequent use after homogeneous process;
Described probio is according to bacterial strain quantitative proportion, Bacillus acidi lactici: bacillus subtilis: bacillus licheniformis: bacillus coagulans is: the mixing probio of the ratio mixing of 1:2:0.3:0.5;
(2) flower bud of lily magnolia extract is prepared:
By 10 parts of flower buds of lily magnolia, add 10 parts of alcohol immersion 3min, then drain ethanol, then keep 20min after adding 50-60 part water boil, after filter residue, both obtain flower bud of lily magnolia extract extract, for subsequent use after sterilizing;
(3) rose is prepared, feverfew extract:
By 3 portions of roses, 15-16 part feverfew, keeps 40min after adding 50 parts of water boils, both obtains plant extraction liquid after filter residue, for subsequent use after sterilizing;
(4) allocate:
By nostoc fermentation slurry, flower bud of lily magnolia extract, rose, feverfew extract, sugar, water, stir after mixing, and mixed liquor is made in homogeneous process;
(5) canned:
Canned under sterile vacuum environment, preserve under normal temperature.
2. the health beverages for the treatment of of allergic rhinitis according to claim 1, is characterized in that:
Step (4) is: by 3-4 part nostoc fermentation slurry, 1-1.5 part flower bud of lily magnolia extract, 3 portions of roses, feverfew extract, 5 parts of sugar, 22-25 part water, stir after mixing, mixed liquor is made in homogeneous process.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107115362A (en) * | 2017-04-28 | 2017-09-01 | 青岛东海药业有限公司 | Application of the bacillus coagulans in prevention or treatment bronchial astehma preparation is prepared |
CN107897370A (en) * | 2017-12-08 | 2018-04-13 | 滁州尹氏油脂有限公司 | A kind of preparation method with the probiotic beverage for alleviating rhinitis effect |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103565972A (en) * | 2013-10-24 | 2014-02-12 | 安徽工贸职业技术学院 | Preparation method of traditional Chinese medicine (TCM) composition for treating allergic rhinitis |
CN103690641A (en) * | 2012-09-27 | 2014-04-02 | 张献奎 | A traditional Chinese medicine used for treating rhinitis |
-
2015
- 2015-10-29 CN CN201510714455.4A patent/CN105394502A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103690641A (en) * | 2012-09-27 | 2014-04-02 | 张献奎 | A traditional Chinese medicine used for treating rhinitis |
CN103565972A (en) * | 2013-10-24 | 2014-02-12 | 安徽工贸职业技术学院 | Preparation method of traditional Chinese medicine (TCM) composition for treating allergic rhinitis |
Non-Patent Citations (1)
Title |
---|
程超等: "葛仙米饮料的研制", 《食品科学》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107115362A (en) * | 2017-04-28 | 2017-09-01 | 青岛东海药业有限公司 | Application of the bacillus coagulans in prevention or treatment bronchial astehma preparation is prepared |
CN107897370A (en) * | 2017-12-08 | 2018-04-13 | 滁州尹氏油脂有限公司 | A kind of preparation method with the probiotic beverage for alleviating rhinitis effect |
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Application publication date: 20160316 |