CN105381058A - Medicine composition for treating burns and scalds - Google Patents
Medicine composition for treating burns and scalds Download PDFInfo
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- CN105381058A CN105381058A CN201510778864.0A CN201510778864A CN105381058A CN 105381058 A CN105381058 A CN 105381058A CN 201510778864 A CN201510778864 A CN 201510778864A CN 105381058 A CN105381058 A CN 105381058A
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/12—Magnesium silicate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
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- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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Abstract
The invention discloses a medicine composition for treating burns and scalds. The medicine composition is prepared from the following medicinal raw materials: oyster, Chinese gall, dragon bone, talcum, borneol, gypsum, propylene glycol, fructus schizandrae, borax, nacre mother of pearl, turtle shell, frankincense and pseudo-ginseng. The medicine composition has the effects of diminishing inflammation and astringing pores to prevent body fluid from extravasating and avoid ulceration and suppuration of scald parts, and is suitable for burns and scalds caused by water, oil, fire, asphalt, electricity and other various reasons, so that small-area burns can scab in one to two days, scars fall off in about five to six days, and the burns can be cured in one week. The medicine composition has a remarkable treatment effect, and cannot leave scar under the condition of timely treatment.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of burn and scald.
Background technology
Burn and scald is a kind of unexpected injury common in live and work, and when and where men and women, old and young likely occur.Clinically, " having one's hair waved, oily boiling hot, burn (burning hot) three major types is generally divided into.Characteristic of disease and water, oil, fire and scalding area size, the depth are relevant.General having one's hair waved is comparatively light, and oil scalds heavier, and burn is heavier.Should process in time after burn and scald, more early better, if dealt with improperly, may serious consequence be caused.If burn and scald area is excessive, excessively dark, serious burn and scald the wounded, skin can be made to lose the function stoping moisture evaporation, increase the weight of dehydration, body hypovolemia, if hypovolemia is to the degree exceeding body compensatory capacity, shock and even death may be caused, therefore for unexpected, burned patient occur, must seek medical advice in time, guarantee life security.
Burn and scald is generally divided into three degree: once burn and scald: only injure epidermal area, injured skin rubefaction, swelling, feels to ache smartly, but anhydrous bubbling out shows.Two degree of burn and scald: injure skin corium, local redness, heating, hurt like hell, have obvious blister.Three degree of burn and scald: full thickness skin, comprise subcutaneous fat, muscle all come to harm, and skin is burned black, downright bad.Burn and scald occurs in Head And Face, though or not at Head And Face, burn and scald area is large, the degree of depth is dark, all belong to serious burn and scald.The pathological change of burn and scald, depends on heat source temperature and heated time.In addition, the generation of burn is also relevant to patient's body conditions with development.Such as: during hot water bag with 40 ~ 50 DEG C of the patient of some sensitive skin, can first degree burn be caused, bad relevant with the conduction of its tissue to heating power.And for example: children's bears a pretty, delicate skin, the reaction of burnt degree, normal than adult be subject to equal area (accounting for body surface %) and the burn of the degree of depth serious.
Infection is the serious threat to burn and scald patient, infects main from wound face: injured rear immunity of organisms declines, and antibacterial will grow at wound face amount reproduction, and enters blood by body fluid, causes septicemia or pyemia.
The medicine for the treatment of burn and scald in the market has dressing, water preparation, unguentum etc., but most unsatisfactory curative effect, healing time is long, normal obstinate, patient is painful, although some medicines are by wound healing, but leave cicatrix after treatment, cicatrix brings inevitable negative effect to the life of the wounded.
Summary of the invention
Object of the present invention is exactly to overcome the above problems, and provides a kind of pharmaceutical composition for the treatment of burn and scald, treatment burn and scald have treatment time short, patient painful little, more after the distinguishing feature of preventing from scar.
The pharmaceutical composition that the present invention treats burn and scald is made up of the crude drug of following weight portion:
Concha Ostreae 8 ~ 10 parts, Galla Chinensis 3 ~ 6 parts, Os Draconis 8 ~ 12 parts, 7 ~ 15 parts, Talcum, Borneolum Syntheticum 1 ~ 3 part, 10 parts ~ 50 parts, Gypsum Fibrosum, propylene glycol 5 ~ 8 parts, Fructus Schisandrae Chinensis 5 ~ 15 parts, Borax 3 ~ 5 parts, Concha Margaritifera 10 ~ 25 parts, Os Draconis 7 ~ 15 parts, Carapax et Plastrum Testudinis 5 ~ 20 parts, Olibanum 5 ~ 15 parts, Radix Notoginseng 3 ~ 5 parts.
As preferably, described pharmaceutical composition is made up of the crude drug of following weight portion:
Concha Ostreae 10 parts, Galla Chinensis 5 parts, Os Draconis 10 parts, 10 parts, Talcum, Borneolum Syntheticum 2 parts, 30 parts, Gypsum Fibrosum, propylene glycol 6 parts, Fructus Schisandrae Chinensis 10 parts, Borax 5 parts, Concha Margaritifera 20 parts, Os Draconis 10 parts, Carapax et Plastrum Testudinis 10 parts, Olibanum 10 parts, Radix Notoginseng 5 parts.
The present invention also provides the preparation containing foregoing pharmaceutical compositions further, and as preferably, described preparation is powder.
The preparation method of described powder:
The crude drug such as Concha Ostreae, Galla Chinensis, Os Draconis, Talcum, Borneolum Syntheticum, Gypsum Fibrosum, propylene glycol, Fructus Schisandrae Chinensis, Borax, Concha Margaritifera, Os Draconis, Carapax et Plastrum Testudinis, Olibanum, Radix Notoginseng are weighed; Medicine after weighing is pulverized respectively except propylene glycol and grinds into fine powder into powder; By ground fine powder medicamental pulverata and mixed with propylene glycol, mix well and get final product application.
The using method of pharmaceutical composition of the present invention: first to the disinfection of burn and scald position, clean for the dead bark complete liquidation of scalding position, smear to affected part equably by the powder made, and presses gently, make it be fixed on affected part, do not bandage.According to the order of severity of burn and scald, adjustment dosage.After waiting for a period of time quietly, if body fluid soaks powder, then add painting one deck again, keep affected part dry.Slight burn and scald can be formed a scab in 24 hours, within 5-6 days, can heal; Large area burn and scald, also recovery from illness in about 20 days, can not leave any cicatrix.
In pharmaceutical composition of the present invention:
Concha Ostreae convergence is solid de-; Galla Chinensis convergence removing toxic substances, hemostasis; Os Draconis tranquillizing and allaying excitement; Talcum heat clearing away removing dampness; The anticorrosion heat radiation pain relieving of Borneolum Syntheticum; Gypsum Fibrosum convergence, heat clearing away; Propylene glycol promotes that drug osmotic absorbs; Fructus Schisandrae Chinensis convergence, hidroschesis; Borax subduing swelling and detoxicating; Concha Margaritifera is calmed the nerves; Os Draconis tranquillizing and allaying excitement, convergence; Carapax et Plastrum Testudinis stops blooding; Olibanum detumescence, pain relieving; Pseudo-ginseng hemostatic analgesic therapy.
Beneficial effect of the present invention is: will first all be removed by the dead bark of scalding position before the drug of topical application, utilization exposes not wrapping technique, powder is smeared affected part, adopt the medicine of Chinese medicine and western medicine compatibility, convergence pore, stop the metabolism of scald place skin at short notice, stoping body fluid to exosmose, would not there is unnecessary body fluid in such scald place.Containing Borneolum Syntheticum, Borax, Olibanum, Radix Notoginseng in medicine composition, can play antiinflammatory, pain relieving, antipruritic effect, the skin at scald place will soon be formed a scab.Because the pore at scald place is restrained under the effect of medicine, body fluid cannot exosmose, thus protects from infection, and ulcer, suppuration phenomenon also would not occur.General medication is once forming a scab completely to affected part two days later, once incrustation sclerosis, skin just can carry out self-regeneration, and this date from final recovery from illness is also just very few.After medication, scald epidermis and exosmose without body fluid, and subcutaneous tissue does not have infected, surperficial medication can't affect hypodermic eubolism.After incrustation comes off, subcutaneous tissue is not damaged, so the place be burned would not leave any cicatrix.After incrustation comes off, skin can be very fine and smooth, and the skin just with surrounding compares some aberration a little.As time goes on, after crossing some months, these aberration are reduced to almost does not see difference.Small size is scalded, and scald vestige in general one month and just can disappear completely, large-area scald then needs the time of about 1 year, after skin recovers automatically, just can't see the vestige of little by little scalding.
The compatibility prescription of pharmaceutical composition of the present invention is that inventor Wen family passes on for many years and the powder for treating scald updated, verify through clinical extensive application, evident in efficacy to burn and scald symptom, treatment time hinge structure shorter, the short misery of the course of disease is little, has the distinguishing feature of preventing from scar more.Medicine of the present invention has effect of antiinflammatory, convergence pore, prevents body fluid from exosmosing, and avoids scalding position and occurs ulcer, suppuration phenomenon.Be applicable to the burn and scald because all kinds of reasons such as water, oil, fire, Colophonium, electricity cause, small size burn and scald is once can forming a scab completely to two days, and incrustation in about five or six days starts to come off, one week just can fully recover, therapeutic effect is remarkable, in time when treatment, can not leave any cicatrix.
Detailed description of the invention
Embodiment 1:
Get Concha Ostreae 8g, Galla Chinensis 3g, Os Draconis 8g, Talcum 7g, Borneolum Syntheticum 1g, Gypsum Fibrosum 10g, propylene glycol 5g, Fructus Schisandrae Chinensis 5g, Borax 3g, Concha Margaritifera 10g, Os Draconis 7g, Carapax et Plastrum Testudinis 5g, Olibanum 5g, Radix Notoginseng 3g.
Above-mentioned raw materials medicine is pulverized respectively except propylene glycol and grinds into fine powder into powder; By ground fine powder medicamental pulverata and mixed with propylene glycol, mix well and can be applied to affected part.
Embodiment 2:
Get Concha Ostreae 10g, Galla Chinensis 5g, Os Draconis 10g, Talcum 10g, Borneolum Syntheticum 2g, Gypsum Fibrosum 30g, propylene glycol 6g, Fructus Schisandrae Chinensis 10g, Borax 5g, Concha Margaritifera 20g, Os Draconis 10g, Carapax et Plastrum Testudinis 10g, Olibanum 10g, Radix Notoginseng 5g.Method for making usage is the same.
Embodiment 3:
Get Concha Ostreae 9g, Galla Chinensis 6g, Os Draconis 12g, Talcum 15g, Borneolum Syntheticum 3g, Gypsum Fibrosum 50g, propylene glycol 8g, Fructus Schisandrae Chinensis 15g, Borax 4g, Concha Margaritifera 25g, Os Draconis 15 parts, Carapax et Plastrum Testudinis 20g, Olibanum 15g, Radix Notoginseng 4 parts.Method for making usage is the same.
Model case:
Case 1: patient is left people from village, Nanhe County, Hebei province Zhao XX, man, 35 one full year of life, has been ironed instep by white lime when within 2005, to clear up white lime in building site, whole instep has been scalded one about five centimetres wide, the large blister of ten centimeter length, the dead bark of scalding position is all removed, after surface sterilization process, after applying medicine of the present invention, twenty four hours is formed a scab, within three or four days, form a scab afterwards and start to come off, within about ten days, forming a scab, it is clean all to come off, and does not leave any cicatrix.
Case 2: patient is Nanhe County, Hebei province left villager's model XX, man, 19 one full year of life, 2005 when site construction, a tractor hauls the cauldron of a bite one meter in diameter about two, the inside is filled with one pot of boiling hot Colophonium, and tractor overturns suddenly, boiling hot Colophonium from top to bottom patient to have watered time.When patient being carried on from the gutter on road at that time, just as black asphalt blocks.Patient's hair and the clothes sticked with it all cut, after surface treatment, after the drug of topical application ten days, he just can normally work outside the home, and does not leave any cicatrix with it.
Case 3: patient is the Xi Zheng village, Nanhe County, Hebei province villager Zheng XX, man, 21 one full year of life, within 2006, go on business in way in Neiqiu, scalded by the high-temperature water gushed out in radiator, face is whole to be damaged, after sterilization and drug of topical application process, second day constipation large black crust on the face, forms a scab and starts to come off for three or five days afterwards, after one or two months, skin recovers as excellent as before on the face.
Case 4: patient is 11 months large girl babys, on August 10th, 2013, when creep on the ground, being placed on the thermos flask on wall limit to having taken off down, the boiled water in kettle directly waters with it child, the shirtfront of child, oxter, and waist is all burned, nearly 20 centimetres wide of area, 30 centimeter length, partial skin comes off, and also has some large blisters in addition.After careful sterilization, Exfoliating Scrub, drug of topical application process, within the 3rd day, scald position and start incrustation, incrustation in the tenth day starts to come off from edge, and recovery from illness in 19 days, does not leave any cicatrix.
Claims (3)
1. treat a pharmaceutical composition for burn and scald, it is characterized in that: described pharmaceutical composition is made up of the crude drug of following weight portion: Concha Ostreae 8 ~ 10 parts, Galla Chinensis 3 ~ 6 parts, Os Draconis 8 ~ 12 parts, 7 ~ 15 parts, Talcum, Borneolum Syntheticum 1 ~ 3 part, 10 parts ~ 50 parts, Gypsum Fibrosum, propylene glycol 5 ~ 8 parts, Fructus Schisandrae Chinensis 5 ~ 15 parts, Borax 3 ~ 5 parts, Concha Margaritifera 10 ~ 25 parts, Os Draconis 7 ~ 15 parts, Carapax et Plastrum Testudinis 5 ~ 20 parts, Olibanum 5 ~ 15 parts, Radix Notoginseng 3 ~ 5 parts.
2. pharmaceutical composition according to claim 1, is characterized in that: described pharmaceutical composition is made up of the crude drug of following weight portion: Concha Ostreae 10 parts, Galla Chinensis 5 parts, Os Draconis 10 parts, 10 parts, Talcum, Borneolum Syntheticum 2 parts, 30 parts, Gypsum Fibrosum, propylene glycol 6 parts, Fructus Schisandrae Chinensis 10 parts, Borax 5 parts, Concha Margaritifera 20 parts, Os Draconis 10 parts, Carapax et Plastrum Testudinis 10 parts, Olibanum 10 parts, Radix Notoginseng 5 parts.
3. the preparation containing the pharmaceutical composition described in claim 1 or 2, is characterized in that: described preparation is powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510778864.0A CN105381058A (en) | 2015-11-16 | 2015-11-16 | Medicine composition for treating burns and scalds |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510778864.0A CN105381058A (en) | 2015-11-16 | 2015-11-16 | Medicine composition for treating burns and scalds |
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| CN105381058A true CN105381058A (en) | 2016-03-09 |
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| CN201510778864.0A Pending CN105381058A (en) | 2015-11-16 | 2015-11-16 | Medicine composition for treating burns and scalds |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113648382A (en) * | 2021-09-18 | 2021-11-16 | 宜宾冠天生物科技有限公司 | Quick-acting composition for treating burns, scalds and infection and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552614A (en) * | 2012-03-08 | 2012-07-11 | 张金国 | Traditional Chinese medicine powder for treating scald and preparation method thereof |
| CN104623304A (en) * | 2015-03-18 | 2015-05-20 | 王竞鹏 | Lotion for treating chronic skin ulcer caused by damp-heat and toxicity accumulation and preparation method of lotion |
-
2015
- 2015-11-16 CN CN201510778864.0A patent/CN105381058A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552614A (en) * | 2012-03-08 | 2012-07-11 | 张金国 | Traditional Chinese medicine powder for treating scald and preparation method thereof |
| CN104623304A (en) * | 2015-03-18 | 2015-05-20 | 王竞鹏 | Lotion for treating chronic skin ulcer caused by damp-heat and toxicity accumulation and preparation method of lotion |
Non-Patent Citations (3)
| Title |
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| 于元波等: "《化瘀消肿膏治疗软组织损伤166例报告》", 25 March 2000 * |
| 国家中医药管理局专业技术资格考试专家委员会编写: "《全国中医药专业技术资格考试大纲与细则》", 30 December 2012 * |
| 张媛主编: "《中药制剂技术》", 30 August 2012 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113648382A (en) * | 2021-09-18 | 2021-11-16 | 宜宾冠天生物科技有限公司 | Quick-acting composition for treating burns, scalds and infection and preparation method thereof |
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Application publication date: 20160309 |