CN105362699A - Traditional Chinese medicine pill used for treating chronic pneumonia and preparation method - Google Patents

Traditional Chinese medicine pill used for treating chronic pneumonia and preparation method Download PDF

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CN105362699A
CN105362699A CN201510962820.3A CN201510962820A CN105362699A CN 105362699 A CN105362699 A CN 105362699A CN 201510962820 A CN201510962820 A CN 201510962820A CN 105362699 A CN105362699 A CN 105362699A
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parts
radix
fructus
lung
chinese medicine
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夏修菲
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
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    • A61K35/56Materials from animals other than mammals
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract

The invention discloses a traditional Chinese medicine pill used for treating chronic pneumonia and a preparation method, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine pill is prepared from adenophora stricta, fructus lycii, polygonatum kingianum, waxgourd seeds, Chinese yam, cortex lycii radicis, sinapis alba, perilla fruit, jujube, trichosanthis radix, dwarf lilyturf roots, tussilago farfara, bletilla striata, folium eriobotryae, all-grass of Winkled Marshweed, fritillaria cirrhosa, cortex mori radicis, luffa flowers, snakegourd fruit, herba houttuyniae, radix glycyrrhizae, gecko and almonds. The traditional Chinese medicine pill is accurate in formula and precise in material selection; according to the monarch, minister, assistant and guide principle, the medicine properties of the selected medicinal materials adapt to and supplement one another, the traditional Chinese medicine pill is special for the disease for disease causes, the traditional Chinese medicine pill has the functions of nourishing livers and kidneys, tonifying spleens and qi, tonifying stomachs, engendering liquid, replenishing vital essence, removing heat, moistening lungs, reducing phlegm, diffusing lungs, suppressing coughs, depressing qi and relieving asthma, and is good in absorption effect, remarkable in treatment effect and free of toxic and side effects and clinical adverse reactions, and the clinical verification shows that the cure rate of the traditional Chinese medicine pill for chronic pneumonia is high.

Description

A kind of medicine pill and preparation method being used for the treatment of chronic pneumonia
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine pill and the preparation method that are used for the treatment of chronic pneumonia.
Background technology
Pneumonia, refers to that the symptom of inflammation appears in the alveolar of pulmonary, and the course of disease is chronic pneumonia more than 3 months persons.The feature of chronic pneumonia is periodically recurrence and worsens, and passes through in undaform.Due to the difference of period of pathological changes, age and individuality, symptom is varied.Resting stage body temperature normal, without obvious sign, almost do not cough, but easily pant when running and upstairs.In the deterioration phase often with pulmonary insufficiency, there is cyanosis and dyspnea, and due to vital capacity and breathing reserve minimizing and breath holding time shortening etc., cause the external respiration dysfunction of hyperventilation.Taking a turn for the better after worsening very slow, even there is puffiness of face, cyanosis, thoracic deformity and drumstick finger, toe in frequent expectoration.Due to emphysema, pulmonary insufficiency and cause pulmonary vascular resistance to increase, pulmonary artery pressure increases, right heart burden, can in half a year in two years pulmonary heart disease occur.Also hepatic insufficiency may be had.Leukocyte increases, and erythrocyte sedimentation rate moderate speeds.Infantile acute pneumonia case fatality rate reduces in recent years, but Children Suffering from Severe Pneumonia does not thoroughly recover sometimes, recurs and develops into chronic pneumonia person is quite not rare.Therefore, chronic pneumonia is prevented and treated in time extremely important.
Doctor trained in Western medicine thinks that the morbidity main cause of primary disease is bacterial infection, virus, rickettsia, chlamydia, mycoplasma, fungus and protozoon etc., and secondly the damage of physics, chemistry and immunogenicity also can cause pneumonia, and lobar pneumonia is many caused by pneumococcal infection.Western medical treatment then mainly through antibiotic and cough-relieving, relieving asthma, eliminate the phlegm and hormone medicine treatment, although curative effect is better in a short time, but toxic and side effects weight, patient tolerability is poor, and certain damage can be caused to immunity of organisms, and apply the risk that antibiotic also increases bacterial drug resistance for a long time, serious impact is caused on the life and health of patient.
The traditional Chinese medical science is thought, pneumonia often because of overstrain, liquor-saturated after when human righteousness's deficiencies such as wind, the heresy of the heresy or wind and cold of experiencing wind heat enters caused by inner heat-transformation.Evil impairing the lung is defended, and ailment said due to cold or exposure bundle table, defends the stagnation of QI and close, therefore see fever with aversion to cold; Lung Qi obstraction, thus cough, asthma; Lung not cloth Tianjin, poly-and be expectorant, hindering in cold-evil is then white rare expectorant, hinders and then sees white sticky expectorant or yellow sputum in pathogenic heat or cold-evil's heat-transformation.Pathogen retardance lung network, then cause chest pain.Evil impairing the lung network, spits blood as seen.If pathogen crosses Sheng, vital QI cannot conquer pathogen, pathogen entering the interior, interior biography nutrient blood, then cyanosis on the face and lips or epistaxis send out speckle; Very then pathogenic heat are caved in, the pathogen attacking the pericardium adversely, illiteracy close thinking, occur unconsciousness and delirium or in silence muddle-headed.If pathogenic heat closing are not declared, the deeper the pathogenic heat,the colder the limbs, four ends are fainted cold.If treat proper, heresy moves back eutopic reduction, the low grade fever of visible calentura convalescent period deficiency of YIN Tianjin wound, the syndrome of feverish sensation in the palms and soles or dry mouth and tougue.Current existing treatment hospital mainly with lung heat clearing eliminating phlegm, preventing phlegm from forming and stopping coughing, regulate the flow of vital energy that to relieving asthma be main, although instant effect, with the passing of time chronic pneumonia patient because falling ill, physical function declines, impaired lung function, needs tonification whole body and recover pulmonary function during treatment, fundamentally cure chronic pneumonia, prevent recurrence.Pill of the present invention, sum up configuration through Long-term clinical checking to form, suit the remedy to the case for the cause of disease, there is effect of nourishing the liver nourishing kidney, invigorating the spleen and replenishing QI, reinforcing stomach reg fluid, replenishing YIN and removing heat, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, lowering the adverse-rising QI to subdue asthma, both can YIN nourishing lung heat clearing, lung moistening kidney tonifying, lung qi dispersing cough-relieving, make again the bottom of heart clearing heat in QI system abundance conditioning spleen renal function, strengthen autoimmunity, block the development of pulmonary disease, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to chronic pneumonia cure rate through clinical verification.
Summary of the invention
The invention provides a kind of medicine pill and the preparation method that are used for the treatment of chronic pneumonia, there is effect of nourishing the liver nourishing kidney, invigorating the spleen and replenishing QI, reinforcing stomach reg fluid, replenishing YIN and removing heat, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, lowering the adverse-rising QI to subdue asthma, cure the disease and ask source treating both the principal and secondary aspects of a disease, to the chronic pneumonia that a variety of causes causes, all there is good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine pill for chronic pneumonia, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine pill of chronic pneumonia, comprise following processing step:
(1) dry clean for Fructus Trichosanthis, grind into powder after pulverizing, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(2) dry clean for Bulbus Fritillariae Cirrhosae, grind into powder after pulverizing, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(3) after Radix Adenophorae (Radix Glehniae), Fructus Lycii, Rhizoma Polygonati, Semen Benincasae, Cortex Lycii, Fructus Perillae, Fructus Jujubae, Radix Ophiopogonis, Flos Farfarae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eriobotryae, Herba Limnophilae rugosae, Cortex Mori, Flos Luffae, Herba Houttuyniae, Radix Glycyrrhizae, Gecko being cleaned, drying, mix homogeneously with the fine powder of step (1), step (2) gained, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(4) Radix Trichosanthis, Semen Armeniacae Amarum are cleaned and dried, put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(5) dry clean for Semen Sinapis Albae, add quantitative rice vinegar and mix thoroughly, after moistening to vinegar is sucked, puts in parch container, heat fried dry with slow fire, taking-up is dried in the air cool.Sieve removes chip, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6) first by even for wheat bran spreading in hot pot, cigarette of waiting rises, add yam slice stir to faint yellow for degree, take out, sieve remove wheat bran, cool, dry, pulverizing is ground into powder, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(7) by the thick paste of step (3), step (4) gained, with step (5), the fine powder of gained mixes in step (6), adds after refined honey stirs, is prepared as the pill of 8 parts every.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Adenophorae (Radix Glehniae): sweet in the mouth; Micro-hardship; Cold nature.Return lung; Stomach warp.Replenishing YIN and removing heat; Moistening the lung and resolving phlegm; Reinforcing stomach reg fluid.Cure mainly deficiency of YIN chronic cough; Consumptive disease is coughed expectorant blood; Cough caused by dryness expectorant is few; Deficiency-heat sore throat; Tianjin wound is thirsty.Compendium of Material Medica is carried: " Radix Adenophorae (Radix Glehniae) is sweet light and cold, and its body is gently empty, special tonifying the lung gas, thus strengthening the spleen and kidney, therefore gold can should it by fire gram person.YANG invigorating and raw cloudy, nourishing YIN and sun processed, must debate also." modern medicine study confirms; Radix Adenophorae (Radix Glehniae) contains volatile oil, coumarin, starch, alkaloid, triterpenic acid, stigmasterol, β-each sterol; improve T cell ratio; improve lymhocyte transformation rate, leukocyte increasing, strengthens macrophage function; extend antibody life period; have antipyretic, ease pain, eliminate the phlegm, function of relievining asthma, strengthen the immunologic function of body fluid and cell, have protection and inhibitory action to irritability and Drug gastric ulcer.
Fructus Lycii: sweet in the mouth; Property is put down.Return liver; Kidney; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; The expensive essence of sexual impotence; Cough due to consumptive disease; To quench one's thirst taking fluids profusely." book on Chinese herbal medicine just " carries: " improve visual and auditory acuity, adds the solid marrow of essence, strengthen the muscle and bone, and kind benefit impairment caused by overstrain, especially only quenches one's thirst." modern medicine study confirm, Fructus Lycii scalable body's immunity, can effectively Tumor suppression grow and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function.
Rhizoma Polygonati: sweet in the mouth; Property is put down.Enter spleen; Lung; Kidney channel.Nourishing YIN and moistening the lung; Invigorating the spleen and replenishing QI; Zishen fill fine.Cure mainly deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body weakness with emaciation is thin; Wind favus disease." book on Chinese herbal medicine meets former " carries: " alleviating distention in middle-JIAO QI invigorating, five Tibetan are in harmonious proportion, and muscle sufficiency, bone marrow is hard by force, is all the merit of nourishing YIN." modern medicine study confirms; the blood glucose that Rhizoma Polygonati causes epinephrine raises significant inhibitory action; have inhibitory action in various degree to common causative fungus; raise Liver Superoxide Dismutase Activity active; reduce myocardium lipofuscin content and reduce; strengthen the tolerance to anoxia, also have antiviral efficacy in addition.
Semen Benincasae: sweet in the mouth; Cold nature.Enter lung; Large intestine channel.Removing heat from the lung and dissipating phlegm; Eliminating carbuncle evacuation of pus; Dampness removing.Cure mainly phlegm-heat cough; Lung abscess; Intestinal carbuncle; Nebulousurine; Leukorrhagia; Foot gas; Edema; Stranguria." hook unit stated by book on Chinese herbal medicine " carries: " in main abdomen, knot is poly-, ulceration pus and blood, stops up, key medicine the most in all the intestines and stomach." medicine clinical research shows, Semen Benincasae has significant immunologic enhancement, increases wide speckle and forms cell number, have obvious inhibitory action to trypsin.
Rhizoma Dioscoreae: sweet in the mouth; Property is put down.Enter lung; Spleen; Kidney channel.Spleen reinforcing; Support lung; Reinforce the kidney; Benefit essence.Cure mainly diarrhea due to hypofunction of the spleen; Lack of appetite edema; Cough and asthma due to lung deficiency; Quench one's thirst; Seminal emission; Leukorrhagia; To suffer from a deficiency of the kidney frequent micturition; Carbuncle is controlled in external; Scrofula." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, control weakness, treat five kinds of strain and seven kinds of impairment." modern medicine study confirms, Rhizoma Dioscoreae can reduce blood glucose, regulates body to non-specific irritant reaction, and effectively the Immunosuppression effect of antagonism cyclophosphamide, stimulates intestinal motility, promotes that intestinal contents is emptying, in addition can also aid digestion, antidiarrheal, eliminate the phlegm.
Cortex Lycii: sweet in the mouth; Cold in nature.Enter lung; Kidney channel.Clearind deficient heat; Purte the white; Removing heat from blood.Cure mainly hectic fever due to deficiency of YIN; Hectic fever due to YIN-deficiency night sweat; Infantile malnutrition generates heat; Dyspnea and cough due to lung-heat; Spit blood; Epistaxis; Hematuria; Quench one's thirst." book on Chinese herbal medicine is stated " carries: " cure mainly deficient fever, alternate attacks of chills and fever, allly see blood disorder, epistaxis, cough blood, cough, breathe heavily, diseases due to endogenous heat of ZANG FU organs, apoplexy, dizzy, convulsion epilepsy, lumbago, migratory arthralgia, beriberi, edema, fidgets due to deficiency, throbs with fear, forgetful, urinary obstruction, reddish and whitish turbid urine." modern medicine study confirms, Cortex Lycii contains the derivant of guanidine, has hypoglycemic activity, has certain alleviate effect to the infringement of islets of langerhans island β cellular prion protein, can block SNE and direct vasodilator.
Semen Sinapis Albae: acrid in the mouth; Warm in nature.Enter lung; Liver; Spleen; Stomach; Pericardium channel.Reduce phlegm by drink; Mass dissipating and swelling eliminating.Cure mainly cough with asthma abundant expectoration; Fullness in the chest and hypochondriac pain; Numb limbs and tense tendons; Arthralgia; Multiple abscess caused by damp-phlegm; Carbuncle of yin nature toxic swelling." detailed outline " carries: " promoting the circulation of QI eliminating phlegm; Except in cold warming up; Loose swollen pain relieving.Control and breathe heavily regurgitation of coughing; Numbness wood foot gas; Muscles and bones waist saves all pains." modern medicine study confirms, Semen Sinapis Albae has significant irritation, antibacterial action, increases bronchial secretion active, eliminates the phlegm.
Fructus Perillae: acrid in the mouth; Warm in nature.Return lung; Large intestine channel.Sending down the abnormal ascending QI; Expectorant; Relieving asthma; Intestine moistening.Cure mainly expectorant and stop up QI rising in reverse order; Cough and asthma; Dryness of the intestine constipation." medicineization justice " carries: " Fructus Perillae patent stagnated phlegm.Cough with dyspnea is gas lift then, and dyspnea with rapid respiration is pulmonary distension then, with this therapeutic method to keep the adverse QI flowing downwards Dingchuan.Heat insulation then expectorant is stopped up, and expectorant knot then vexed pain, with this eliminating phlegm eliminating stagnation." modern medicine study confirms, Fructus Perillae has and reduces blood fat, blood pressure, anticoagulant, antioxidation, anticancer, and significant bacteriostasis.
Fructus Jujubae: sweet in the mouth; Temperature.Return spleen; Stomach warp.Tonifying the spleen and stomach; Replenishing QI and blood; Tranquilizing mind; Battalion is adjusted to defend; And the property of medicine.Cure mainly weakness of the spleen and stomach; Insufficiency of vital energy and blood; Anorexia and loose stool; Fatigue and weakness; Palpitation and insomnia; Woman hysteria; Disharmony of nutrient QI with defensive QI." book on Chinese herbal medicine remittance speech ": Shen Shi says, and the sweet profit cream of this medicine coagulates, kind nourishing YIN sun, QI and blood, body fluid, venation, muscle Yu, bone marrow, and all are deficient, without shoulding not it.As imperial Tan Fang controls palpitation with fear palpitation with a distress feeling, dimly forgetful, will meaning stupor, spirit is not kept, or middle gas discord, poor appetite, and hundred body lazynesses are heavy, and muscle is thin, and the card that this belongs to the heart, spleen two hides unit god loss, must control it with Fructus Jujubae.Assistant Pericarpium Citri Reticulatae, adjusts the empty stagnant expectorant of the smooth middle part of gastric cavity.
Radix Trichosanthis: sweet in the mouth; Micro-hardship; Cold nature.Return lung; Stomach warp.Clearing away heat and promoting production of body fluid; Moistening the lung and resolving phlegm; Detumescence and apocenosis.Cure mainly calentura thirsty; To quench one's thirst polydipsia; Lung-heat type cough; Sore swollen toxin." herbal classic is met former " carries: " fall heat-phlegm on diaphragm, moisten excessive thirst in the heart, except time disease fanatic, wine of dispelling illness is wet yellow, controls carbuncle and ulcer removing toxic substances and promoting pus discharge." modern medicine study confirmation; Radix Trichosanthis is rich in trichosanthin; have immunostimulation and immunosuppressive action; suppress virus replication procreation; reduce the viable count be infected by the virus in immunocyte; can fall glycopenia activity, have certain inhibitory action to Hemolytic streptococcus, Diplococcus pneumoniae, diphtheria corynebacterium.
Radix Ophiopogonis: sweet in the mouth; Micro-hardship; Cold in nature.Return lung; Stomach; Heart channel.Nourishing YIN and moistening the lung; Reinforcing stomach reg fluid; Clear away heart-fire relieving restlessness.Cure mainly dryness of the lung dry cough; Lung abscess; Deficiency of YIN chronic cough; Tianjin wound is thirsty; Quench one's thirst; Vexed insomnia; Have sore throat; Dryness of the intestine constipation; Heat in blood tells nosebleed." not Lu ": " treat heavy sensation of the body icteric sclera, rami cardiaci inferiores is full, asthenia exopathogenic heat, and dry mouth is thirsty, anti-nausea, and more flaccidity falls, and reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protects god, determine lung qi, settling five organs, makes us fertile and is good for."
Flos Farfarae: acrid in the mouth; Micro-sweet; Warm in nature.Return lung meridian.Nourishing the lung to keep the adverse QI downward; Preventing phlegm from forming and stopping coughing.Cure mainly new chronic cough to cough; Asthma; Chronic cough hemoptysis." property of medicine opinion " carries: " the main treatment lung qi heart is urged, and anxious hot weary labor, the company of coughing is without cease, and tears saliva is sticky.Control consumptive lung disease lung abscess vomiting pus." modern medicine study confirmation, Flos Farfarae has obvious antitussive, eliminates the phlegm and antiasthmatic effect, can improve the excitement levels of respiratory system, has inhibitory action to the platelet aggregation that platelet activating factor causes, and Flos Farfarae ether extracting solution has bronchorelaxing activity.Ethyl acetate ethanol extraction, the former has phlegm-dispelling functions, and ethanol has antitussive effect.
The Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth; Sweet; Puckery; Cold nature.Enter lung; Liver; Stomach warp.Eliminating phlegm and stopping cough; Promoting blood circulation and hemostasis.Cure mainly cough with copious phlegm; Hemoptysis; Mastitis; Traumatic injury; Traumatic hemorrhage." Japan hanako materia medica " carries: " spasmolytic is evil, blood is evil, and dysentery, acute conjunctivitis, crux, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid wart, cutter arrow skin ulcer flutters damage, warm malaria, dysentery, sore due to scald and burn, granulation promoting pain relieving, migratory arthralgia." modern medicine study confirmation, the Pseudobulbus Bletillae (Rhizoma Bletillae) is rich in colloid, starch, volatilization wet goods, effectively resists bacillus, suppresses the activity of plasmin, is widely used in all kinds of traumatic hemorrhage.
Folium Eriobotryae: bitter in the mouth; Pungent; Cold in nature; Nontoxic.Enter lung; The heart; Stomach warp.Clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI; Quench the thirst.Cure mainly lung-heat phlegmatic cough; Deficiency of YIN chronic cough; Hemoptysis; Epistaxis; Gastric heat is vomitted dirty." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " cough-relieving is coughed, sputum eliminating to stop asthma, and can break expectorant silk, changes pertinacious phlegm, and loose shouting is breathed heavily, only tachypnea." modern medicine study confirmation; amygdalin contained by Folium Eriobotryae is decomposited Microamounts of Hydrogen cyanic acid at lower digestive tract by microbial enzyme; the latter has sedation to respiratory center; therefore have antiasthmatic effect effect; and on Carrageenan edema has powerful inhibitory action, and contained sesquiterpene glycoside and polyhydroxy triterpene glycoside significantly can reduce blood glucose.
Herba Limnophilae rugosae: acrid in the mouth; Sweet; Warm in nature.Return lung; Spleen; Stomach warp.Clearing away heat and expelling pathogen in the exterior, expelling wind and removing dampness, cough-relieving pain relieving.For flu, laryngopharynx swelling and pain, cough due to lung-heat, bronchitis, stomachache." Chinese herbal medicine is commonly used in Sichuan ": " stomach invigorating, pleasant, resolving depression, diuresis.Dispelling the wind and dampness pathogens pathogenic heat is had a headache, edema, edema due to deficiency, peratodynia, distension and fullness of the chest and abdomen."
Bulbus Fritillariae Cirrhosae: sweet in the mouth; Bitter; Cold nature.Return lung; Heart channel.Clearing heat and moistening lung; Preventing phlegm from forming and stopping coughing; Mass dissipating and swelling eliminating.Cure mainly the deficiency of the lung; Chronic cough; Cough due to consumptive disease; Cough caused by dryness-heat; Lung abscess; Scrofula; Carbuncle; Acute mastitis." Changsha medicine solution " carries: " property of Bulbus Fritillariae Uninbracteatae bitter cold, expel the heat-evil cool gold, the turbid descending expectorant, and its power is non-little, right clearing heat in the lung and unbeaten gastric qi, very here praiseworthy." modern medicine study confirmation, Bulbus Fritillariae Cirrhosae has significant antitussive and phlegm-dispelling functions, significantly suppresses pepsin and stress ulcer, suppresses central nervous system.
Cortex Mori: sweet in the mouth; Pungent; Cold in nature.Return lung; Spleen channel.Eliminating pathogen from the lung for relieving asthma; Inducing diuresis to remove edema.Cure mainly lung-heat and breathe heavily expectorant; Diseases caused by retention of fluid stops lung; Distension dyspnea with rapid respiration; Edema; Foot gas; Dysuria." medicineization justice ": Cortex Mori, heat radiation, cure mainly dyspnea with fullness of the chest cough, heat-phlegm hemoptysis, all hold back by excess pathogen is strongly fragrant, lung key must not be unobstructed, and what ooze whereby falls apart it, in order to lung qi, all card spontaneous recovery.Therefore the having a surplus of cloud eliminating the pathogens from the lung, Cortex Mori.Control the outer aqueous vapor edema of flesh side film and skin pathogenic heat with this, floating wind-dryness is itched, and knows and can go it.Same Flos Chrysanthemi, Seem Lablab Album stuffy nose relieving plug heat are stopped up, and conjunction Radix Adenophorae (Radix Glehniae), the Radix Astragali stop the red hematochezia of intestinal all imitates.Modern study proves: Cortex Mori has diuresis and catharsis effect, has certain effect to smooth muscle tool, has calmness and stable, convulsion, analgesia, the effect such as antibacterial.
Flos Luffae: sweet in the mouth; Micro-hardship; Cold in nature.Heat-clearing and toxic substances removing; Preventing phlegm from forming and stopping coughing.Cure mainly cough due to lung-heat; Pharyngalgia; Sinusitis; Furuncle swelling toxin; Hemorrhoid." the southern regions of the Yunnan Province book on Chinese herbal medicine ": clearing away lung-heat, the expectorant therapeutic method to keep the adverse QI flowing downwards, cough-relieving, only throat pain, disappear excessive thirst, reducing the minister-fire.
Fructus Trichosanthis: sweet-bitter flavor; Cold in nature.Enter lung; Stomach warp.Lung moistening; Reduce phlegm; Eliminating stagnation; Intestine moistening.Cure mainly phlegm-heat cough; The thoracic obstruction; Blocked-up chest; Consumptive lung disease hemoptysis; Quench one's thirst; Jaundice; Constipation; Carbuncle from the beginning of." detailed outline " carries: " lung moistening is dry, pathogenic fire reducing, and the main thoracic obstruction, controls cough, and clearing away phlegm is tied, logical hot and suffocating in the heart." modern medicine study confirms, Fructus Trichosanthis containing triterpene saponin, fatty oil, several amino acids and alkaloid, have eliminate the phlegm, coronary artery dilator, increase coronary flow, anti-hypoxia, blood fat reducing effect, the treatment clinically for coronary heart disease has good curative effect.
Herba Houttuyniae: acrid in the mouth; Cold in nature.Enter liver; Lung meridian.Heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Cure mainly lung abscess vomiting pus; Expectorant dyspnea of heat type is coughed; Larynx; Hematodiarrhoea; Carbuncle sore tumefacting virus; Pyretic stranguria." conventional Chinese herbal medicine handbook " carries: " eliminating inflammation and expelling toxin, inducing diuresis to remove edema.Control upper respiratory tract infection, lung abscess, urinary tract inflammation and other position suppurative inflammation, venom." modern medicine study confirmation; Herba Houttuyniae can strengthen the phagocytic activity of WBC; improve immunity of organisms; all have inhibitory action to various microorganism, also has significant antagonism, antiviral, diuresis, analgesia, antitussive, hemostasis, suppression serous secretion in addition, promotes tissue regeneration, calmness, anticonvulsant action.
Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have anti-gastric-ulcer, gastritis effect in addition.
Gecko: salty in the mouth; Property is put down.Return lung; Kidney channel.Kidney tonifying tonifying the lung; Dingchuan antitussive.Cure mainly: deficiency of both the lung and kidney asthma and cough, cough due to consumptive disease; Spitting of blood; Impotence due to deficiency of the kidney; Seminal emission; Frequent micturition; Quench one's thirst." detailed outline ": tonifying the lung gas, benefiting essence-blood, Dingchuan antitussive, treats lung abscess and quenches one's thirst, supporing yang road.Modern medicine study shows: Gecko ethanol extract has obvious antiasthmatic effect to asthma caused by acetylcholine, also has direct relexation to isolated tracheal.
Semen Armeniacae Amarum: bitter in the mouth; Warm in nature; Poisonous.Enter lung; Spleen; Large intestine channel.Expelling phlegm for arresting cough; Relieving asthma; Intestine moistening; The therapeutic method to keep the adverse QI flowing downwards opens numbness.Cure mainly exogenous cough; Dyspnea with fullness of the chest; The cough due to dryness; Cold renal mass; Infantile convulsion; The thoracic obstruction; Stomachache due to dyspepsia; Metrorrhagia; Deaf; Infantile malnutrition with edema and abdominal distention; Damp and hot stranguria; Scabies; Sore throat; Dryness of the intestine constipation." property of medicine opinion " carries: " control abdomen numbness obstructed, diaphoresis, main epidemic febrile disease.Control spasm in the epigastrium completely pain, except trusted subordinate is unhappy, treat lung qi cough, dyspnea, profit cardiopulmonary, can make soup with cheese, benefit profit information." modern medicine study confirmation; Semen Armeniacae Amarum effectively can control the content of cholesterol in human body; significantly reduce the initiation potential of heart disease and multiple chronic disease, have the effects such as lung moistening, cough-relieving, laxation, have certain mitigation to the disease such as dry cough without phlegm, chronic cough of deficiency lung.
The present invention compared with prior art, has following beneficial effect:
The present invention selects medical material, the property of medicine is suitable mutually auxiliary mutually, the causes of disease such as the exopathogen for initiation chronic pneumonia violates lung, evil impairing the lung is defended, Lung Qi obstraction are suited the remedy to the case, there is effect of nourishing the liver nourishing kidney, invigorating the spleen and replenishing QI, reinforcing stomach reg fluid, replenishing YIN and removing heat, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, lowering the adverse-rising QI to subdue asthma, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to chronic pneumonia cure rate through clinical verification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) dry clean for Fructus Trichosanthis, grind into powder after pulverizing, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(2) dry clean for Bulbus Fritillariae Cirrhosae, grind into powder after pulverizing, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(3) after Radix Adenophorae (Radix Glehniae), Fructus Lycii, Rhizoma Polygonati, Semen Benincasae, Cortex Lycii, Fructus Perillae, Fructus Jujubae, Radix Ophiopogonis, Flos Farfarae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eriobotryae, Herba Limnophilae rugosae, Cortex Mori, Flos Luffae, Herba Houttuyniae, Radix Glycyrrhizae, Gecko being cleaned, drying, mix homogeneously with the fine powder of step (1), step (2) gained, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(4) Radix Trichosanthis, Semen Armeniacae Amarum are cleaned and dried, put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(5) dry clean for Semen Sinapis Albae, add quantitative rice vinegar and mix thoroughly, after moistening to vinegar is sucked, puts in parch container, heat fried dry with slow fire, taking-up is dried in the air cool.Sieve removes chip, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6) first by even for wheat bran spreading in hot pot, cigarette of waiting rises, add yam slice stir to faint yellow for degree, take out, sieve remove wheat bran, cool, dry, pulverizing is ground into powder, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(7) by the thick paste of step (3), step (4) gained, with step (5), the fine powder of gained mixes in step (6), adds after refined honey stirs, is prepared as the pill of 8 parts every.
Usage and dosage: oral, every day 3 times, each 1 ball, one hour ante cibum, with warm water delivery service, 20 days was a course for the treatment of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
The routine clinical observation of chronic pneumonia patient 80 selecting my institute to make a definite diagnosis, patient is divided into two groups at random.Treatment group 40 example, wherein male 23 example, women 17 example, 7 ~ 59 years old age, 42.6 years old mean age.Matched group 40 example, wherein male 24 example, women 16 example, 9 ~ 57 years old age, 41.4 years old mean age.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, oral, every day 3 times, each 1 ball, and one hour ante cibum, with warm water delivery service, 20 days was a course for the treatment of.Matched group is according to the patient's condition of the chronic pneumonia diagnosed out, adopt the western medical treatment means such as Conventional antibiotic, according to the medicine such as state of an illness state and physical condition choose reasonable penicillin, clindamycin, cephalosporin of patient, and Reasonable adjustment dosage, be in addition give cough-relieving according to the clinical manifestation routine of patient, reduce phlegm, the medicine such as to relieving asthma treated.
3, efficacy determination:
(1) cure: the clinical symptoms of patient disappears completely, chest X-ray recovers normal, and health recovers normal substantially.
(2) take a turn for the better: the clinical symptoms of patient is obviously alleviated, and chest X-ray turns for the better by and large, and health is clearly better.
(3) invalid: symptom is with treating front no significant difference.
4, result
Cure 27 examples in treatment group, take a turn for the better 11 examples, invalid 2 examples, cure rate 67.5%, total effective rate 95%.
Cure 24 examples in matched group, take a turn for the better 9 examples, invalid 7 examples, cure rate 60%, total effective rate 82.5%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Lee's ××, man, 45 years old.There is sense of discomfort in this patient pulmonary's nearly half a year often, and throat has dry cough, and pulmonary is stuffy, difficulty of sometimes breathing, and ct sheet display inferior lobe of right lung strip high density shadow, the fuzzy shadow of inferior lobe of left lung patch shape and bar Suo Ying, be diagnosed as two lung chronic pneumonia.Through taking medicine of the present invention, oral, every day 3 times, each 1 ball, one hour ante cibum, with warm water delivery service, 20 days was a course for the treatment of, and after taking 1 course for the treatment of, above-mentioned symptom disappears substantially, and x-ray checks that pulmonary recovers normal.Follow the doctor's advice after continuing to take 1 course for the treatment of of medicine of the present invention, health complete recovery of health, fully recovers.
2, Liu's ××, female, 8 years old.Patient started cough before 2 years, time light time heavy, most of time is all very slight, one day just a little sound, but increases the weight of about 3-5 time always among 1 year, oneself gets it filled and takes, take a turn for the better after medication.But fever and cough again before January, continues 8 days, come institute and go to a doctor, check breast CT, find superior lobe of left lung, inferior lobe patch bar shadow, the bright degree in left lung local increases, conclusion: superior lobe of left lung, inferior lobe chronic inflammatory disease.Be diagnosed as chronic pneumonia.Through taking medicine of the present invention, oral, every day 3 times, each 1 ball, one hour ante cibum, with warm water delivery service, 20 days was a course for the treatment of, and after taking 2 courses for the treatment of, clinical symptoms disappears completely, and x-ray checks that pulmonary recovers normal, and health complete recovery of health, fully recovers.
Pill of the present invention is summed up configuration through Long-term clinical checking and is formed, and suits the remedy to the case for the cause of disease, in side the Chinese medicine such as Fructus Lycii, Rhizoma Polygonati, Rhizoma Dioscoreae, Fructus Jujubae can nourishing the liver, nourishing kidney, lung moistening, tonifying the spleen and stomach; In side the Chinese medicine such as Radix Adenophorae (Radix Glehniae), Radix Trichosanthis, Radix Ophiopogonis can replenishing YIN and removing heat, moistening the lung and resolving phlegm, reinforcing stomach reg fluid; In side the Chinese medicine such as Cortex Lycii, Herba Limnophilae rugosae can clearing away heat and expelling pathogen in the exterior, removing heat from blood cough-relieving; In side the Chinese medicine such as Folium Eriobotryae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Farfarae, Bulbus Fritillariae Cirrhosae can clearing heat and moistening lung, eliminating phlegm and stopping cough; In side, the Chinese medicine such as Herba Houttuyniae, Flos Luffae can heat-clearing and toxic substances removing, removing pus and relieving carbuncle; The cough-relieving of the Chinese medicine such as Semen Armeniacae Amarum, Cortex Mori cocoa lung qi dispersing, lowering the adverse-rising QI to subdue asthma in side; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription in side; All medicines share the effect of playing nourishing the liver nourishing kidney, invigorating the spleen and replenishing QI, reinforcing stomach reg fluid, replenishing YIN and removing heat, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, lowering the adverse-rising QI to subdue asthma altogether, both can YIN nourishing lung heat clearing, lung moistening kidney tonifying, lung qi dispersing cough-relieving, make again the bottom of heart clearing heat in QI system abundance conditioning spleen renal function, strengthen autoimmunity, block the development of pulmonary disease, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to chronic pneumonia cure rate through clinical verification.

Claims (4)

1. be used for the treatment of a medicine pill for chronic pneumonia, it is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Radix Adenophorae (Radix Glehniae) 67 ~ 80 parts of Fructus Lycii 64 ~ 77 parts of Rhizoma Polygonatis 60 ~ 74 parts of Semen Benincasaes 57 ~ 71 parts
Rhizoma Dioscoreae 54 ~ 68 parts of Cortex Lycii 51 ~ 65 parts of Semen Sinapis Albaes 48 ~ 62 parts of Fructus Perillaes 45 ~ 59 parts
Fructus Jujubae 42 ~ 56 parts of Radix Trichosanthis 39 ~ 53 parts of Radix Ophiopogonis 36 ~ 50 portions of Flos Farfaraees 33 ~ 47 parts
The Pseudobulbus Bletillae (Rhizoma Bletillae) 30 ~ 43 parts of Folium Eriobotryaes 27 ~ 40 portions of Herba Limnophilae rugosaes 24 ~ 37 parts of Bulbus Fritillariae Cirrhosae 22 ~ 34 parts
Cortex Mori 19 ~ 31 parts of Flos Luffaes 16 ~ 27 parts of Fructus Trichosanthis 13 ~ 23 parts of Herba Houttuyniae 9 ~ 18 parts
2 ~ 9 parts, Radix Glycyrrhizae 7 ~ 15 portions of Geckos 4 ~ 12 parts of Semen Armeniacae Amarums.
2. a kind of medicine pill being used for the treatment of chronic pneumonia according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Radix Adenophorae (Radix Glehniae) 70 ~ 76 parts of Fructus Lycii 67 ~ 73 parts of Rhizoma Polygonatis 63 ~ 71 parts of Semen Benincasaes 60 ~ 68 parts
Rhizoma Dioscoreae 57 ~ 65 parts of Cortex Lycii 54 ~ 62 parts of Semen Sinapis Albaes 51 ~ 59 parts of Fructus Perillaes 48 ~ 56 parts
Fructus Jujubae 45 ~ 53 parts of Radix Trichosanthis 42 ~ 50 parts of Radix Ophiopogonis 39 ~ 47 portions of Flos Farfaraees 36 ~ 44 parts
The Pseudobulbus Bletillae (Rhizoma Bletillae) 33 ~ 40 parts of Folium Eriobotryaes 30 ~ 37 portions of Herba Limnophilae rugosaes 27 ~ 34 parts of Bulbus Fritillariae Cirrhosae 25 ~ 31 parts
Cortex Mori 22 ~ 27 parts of Flos Luffaes 19 ~ 24 parts of Fructus Trichosanthis 16 ~ 20 parts of Herba Houttuyniae 12 ~ 15 parts
4 ~ 7 parts, Radix Glycyrrhizae 9 ~ 13 portions of Geckos 6 ~ 10 parts of Semen Armeniacae Amarums.
3. a kind of medicine pill being used for the treatment of chronic pneumonia according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Radix Adenophorae (Radix Glehniae) 73 parts of Fructus Lycii 70 parts of Rhizoma Polygonatis 67 parts of Semen Benincasaes 64 parts
Rhizoma Dioscoreae 61 parts of Cortex Lycii 58 parts of Semen Sinapis Albaes 55 parts of Fructus Perillaes 52 parts
Fructus Jujubae 49 parts of Radix Trichosanthis 46 parts of Radix Ophiopogonis 43 portions of Flos Farfaraees 40 parts
The Pseudobulbus Bletillae (Rhizoma Bletillae) 37 parts of Folium Eriobotryaes 34 portions of Herba Limnophilae rugosaes 31 parts of Bulbus Fritillariae Cirrhosae 28 parts
Cortex Mori 25 parts of Flos Luffaes 21 parts of Fructus Trichosanthis 18 parts of Herba Houttuyniae 14 parts
5 parts, Radix Glycyrrhizae 11 portions of Geckos 7 parts of Semen Armeniacae Amarums.
4. a kind of preparation method being used for the treatment of the medicine pill of chronic pneumonia according to claims 1 to 3, is characterized in that, comprise following processing step:
(1) dry clean for Fructus Trichosanthis, grind into powder after pulverizing, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(2) dry clean for Bulbus Fritillariae Cirrhosae, grind into powder after pulverizing, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(3) after Radix Adenophorae (Radix Glehniae), Fructus Lycii, Rhizoma Polygonati, Semen Benincasae, Cortex Lycii, Fructus Perillae, Fructus Jujubae, Radix Ophiopogonis, Flos Farfarae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Folium Eriobotryae, Herba Limnophilae rugosae, Cortex Mori, Flos Luffae, Herba Houttuyniae, Radix Glycyrrhizae, Gecko being cleaned, drying, mix homogeneously with the fine powder of step (1), step (2) gained, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(4) Radix Trichosanthis, Semen Armeniacae Amarum are cleaned and dried, put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(5) dry clean for Semen Sinapis Albae, add quantitative rice vinegar and mix thoroughly, after moistening to vinegar is sucked, puts in parch container, heat fried dry with slow fire, taking-up is dried in the air cool.Sieve removes chip, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6) first by even for wheat bran spreading in hot pot, cigarette of waiting rises, add yam slice stir to faint yellow for degree, take out, sieve remove wheat bran, cool, dry, pulverizing is ground into powder, cross 120 order dusting covers, obtain fine powder, for subsequent use;
(7) by the thick paste of step (3), step (4) gained, with step (5), the fine powder of gained mixes in step (6), adds after refined honey stirs, is prepared as the pill of every 8g.
CN201510962820.3A 2015-12-18 2015-12-18 Traditional Chinese medicine pill used for treating chronic pneumonia and preparation method Pending CN105362699A (en)

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