CN105343952A - Blood pump achieving self-sufficient energy - Google Patents
Blood pump achieving self-sufficient energy Download PDFInfo
- Publication number
- CN105343952A CN105343952A CN201510891189.2A CN201510891189A CN105343952A CN 105343952 A CN105343952 A CN 105343952A CN 201510891189 A CN201510891189 A CN 201510891189A CN 105343952 A CN105343952 A CN 105343952A
- Authority
- CN
- China
- Prior art keywords
- blood pump
- self
- fuel cell
- biological fuel
- power supply
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/871—Energy supply devices; Converters therefor
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
- H01M4/00—Electrodes
- H01M4/86—Inert electrodes with catalytic activity, e.g. for fuel cells
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
- H01M8/00—Fuel cells; Manufacture thereof
- H01M8/16—Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
- Y02E60/30—Hydrogen technology
- Y02E60/50—Fuel cells
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Manufacturing & Machinery (AREA)
- Sustainable Development (AREA)
- Sustainable Energy (AREA)
- Anesthesiology (AREA)
- Mechanical Engineering (AREA)
- Cardiology (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a blood pump achieving self-sufficient energy. The blood pump achieving the self-sufficient energy utilizes a biological fuel cell (5) which is internally installed in a human body to supply electricity to a blood pump body (3) implanted into the human body, an external power source is not needed for the blood pump body (3), the electric energy is produced continuously to supply the electricity only by utilizing the characteristic of an automatic update of tissue fluid in the human body, self-supplying electric energy of the blood pump body (3) is achieved, and infection caused due to the fact that an external power source lead passes through the skin is eliminated. According to the blood pump achieving the self-sufficient energy, the structure is simple, the external power source is not needed for power supply, the biological fuel cell is adopted to supply the electricity, the service life is long, and the infection caused due to the fact that the a blood pump power supply power line passes through the skin can be eliminated.
Description
Technical field
The present invention relates to a kind of self-supporting energy blood pump, belong to mechanical engineering and field of biomedicine technology, self-supporting energy blood pump utilizes the biological fuel cell be placed in human body to power, battery utilizes glucose and oxygen generation electrochemical reaction electrogenesis in subcutaneous tissue liquid, solves the energy supply problem of implanted blood pump.
Background technology
The fast development of modern medical techniques, various treatment or complementary implantable medical device have applied to each position of human body, bring the opportunity recovering physiological function to patient.Heart disease is the principal element threatening human health, and it is best Therapeutic Method that donor's heart is transplanted, and is limited to donor's heart shortage at present, therefore replaces donor's heart just to bring the hope for the treatment of to patient with blood pump.Blood pump is also known as artificial heart pump, and it is the means that a kind of effective treatment myocardial function is incomplete that blood pump is transplanted.The driving-energy of implanted blood pump is an important step, the driving-energy of current blood pump is the method adopting external power supply input, namely cortex wire is drawn human body through human body skin by operation by external power supply input, by cortex wire by the energy delivery of extraneous battery to blood pump, so very easily cause infection, affect the quality of life after corrective surgery.The key addressed this problem is that, how for blood pump provides stable electric energy, if directly at the chemical cell that people's et al. Ke is traditional, such as lithium battery, also exists the problem such as limited battery life, the leakage of battery chemistries test solution.Therefore, the present invention can utilize the battery of bioenergy power generation in human body to solve blood pump energy supply problem.
Biological fuel cell is a new energy technology, is to utilize enzyme or microorganism cultures as catalyst, is the device of electric energy by the chemical energy of Organic substance as the material such as ethanol, glucose.Enzyme thermistor devices and microbiological fuel cell can be divided at present according to the form difference of catalyst, but study carefully its catalytic nature, the essence of the microorganism catalysis of microbiological fuel cell is also utilize the enzyme in microbial body to carry out catalysis, therefore, can say that the catalytic nature of two kinds of batteries does not have substantial difference, all utilize enzyme to carry out catalysis electrode reaction, so enzyme thermistor devices can as main direction of studying.Glucose is more common monosaccharide, exist in tissue liquid, and human body constant temperature and acid-base value condition, also the biological activity that glucose enzyme keeps higher is just being applicable to, available glucoseoxidase makes cell anode catalyst, cell cathode catalyst generally selects the precious metals such as platinum to make catalyst, and the electrode made as catalyst based on glucose enzyme and platino is comparatively common in biological fuel cell field.
Current implanted blood pump is that external connection battery provides energy, the driving power supply line of blood pump needs through human body skin, easily cause infection after surgery, this invention utilizes the biological fuel cell formed in human body to be blood pump energy supply, thus realize the self energizing of blood in human body in pump.
Application number is the patent documentation " a kind of human implantable colonic forms the device of microbiological fuel cell " of 201110279369.7, utilizes enteric microorganism and content electrogenesis, describes a kind of microbial fuel cells system.Application number is application and the preparation that 201210560699.8 " enzyme thermistor devices electrode and the application in the enzyme thermistor devices of preparation two rooms " describe enzyme biotinylated biomolecule fuel cell electrode, illustrates feasibility and the stability of glucose biological fuel cell.Application number 201410706730.3 " a kind of preparation method of paper substrate self energizing biosensor and application ", biological fuel cell is incorporated in three-dimensional hollow miniflow paper chip, utilize the signal of telecommunication that biological fuel cell produces, break away from the restriction to outside powering device, realize the self energizing of detection system.The common ground of these patents of invention all describes the feasibility utilizing biological fuel cell electric energy, namely can realize load energy supply.
Summary of the invention
Technical problem to be solved by this invention is: propose a kind of self-supporting energy blood pump, this self-supporting energy blood pump is powered based on the hypodermic biological fuel cell of implant into body, the power line of blood pump, without the need to through human body skin, solves the infection problems that power line causes through human body skin.Utilize biological fuel cell technology to solve blood pump energy supply problem, utilize the feature of the reaction substrate such as glucose and oxygen continuous updating in human body, the generation electric energy that biological fuel cell can be continual and steady, has good biocompatibility and persistency.
The present invention solves its technical problem and adopts following technical scheme:
Self-supporting energy blood pump provided by the invention, it utilizes and is built in biological fuel cell in human body for the blood pump in implant into body and powers, blood pump is without the need to external power supply, only need the feature utilizing people's in-vivo tissue liquid automatically to upgrade to produce electric energy continuously to power, realize the confession electric energy of blood pump, and eliminate because external power supply lead-in wire is through the infection caused by skin.
Described blood pump and biological fuel cell, its power line without the need to being directly connected by power supply line through skin in human body, and the import and export end of blood pump is respectively connected with the ventricle of human heart, large artery trunks respectively by an artificial blood vessel.
Described biological fuel cell adopts the electrode body of multiple structure, be made up of the negative electrode be arranged in order, cathode catalysis layer, PEM, anode catalyst layer and anode, the electric energy that this electrode body produces is drawn by two power supply lines, and these two power supply lines are connected with the power supply of blood pump respectively.
The electrode body of described multiple structure, it utilizes glucose in tissue liquid and oxygen electrogenesis, utilize the physiological characteristics of tissue liquid to realize the automatic renewal of electrochemical reaction substrate, the by-product after electrochemical reaction is carbon dioxide to human non-toxic's side effect and water.
Described negative electrode is the oxygen electrode of biological fuel cell, mainly utilizes the dissolved oxygen in tissue liquid, and this oxygen electrode is a kind of platinum carbon electrode be made up of biocompatibility and the good porous platinum carbon Nanoalloy material of electric conductivity.
Described anode is the fuel electrode of biological fuel cell, comprises porous carbon, carbon felt, carbon paper or carbon fibre material make by porous material.
Described PEM, adopt soft, proton can through the perfluorinated sulfonic acid class material that comprises make, by the method for hot pressing, PEM is placed in the centre of anode and negative electrode.
Described anode and negative electrode, its supporting layer adopts porous carbon cloth to make.
Above-mentioned self-supporting energy blood pump provided by the invention, when it uses, adopts the series connection of multiple biological fuel cell or parallel way to power.
The present invention is based on biological fuel cell technology, and object is biological fuel cell implant into body, utilizes the glucose in tissue liquid and oxygen electrogenesis, solves people's vivo implantation type blood pump and relies on external power supply for the problem of electric energy.Directly for blood pump is powered, can not need to penetrate human body skin for electrical lead at the biological fuel cell of subcutis, the postoperative infection risk of patient can be reduced, improve minimal invasive treatment's quality.
Self-supporting energy blood pump is implanted at human body, and the import and export of blood pump are connected with artificial blood vessel by the material (as politef) of good biocompatibility, stable chemical performance, and artificial blood vessel is connected with large artery trunks with left ventricle again.Biological fuel cell is arranged on human abdomen's subcutaneous tissue, and the both positive and negative polarity of biological fuel cell is connected with the power line of blood pump.
The present invention compared with prior art has following main advantage:
1. the mini-medical equipment of the implant into body of major part implantation at present adopts internal battery to power, and service life of lithium battery is limited, changes and needs again to perform the operation, and self-supporting energy blood pump of the present invention adopts biological fuel cell to power, long service life, without the need to changing;
2. current implanted blood pump adopts external power supply, and by operation, blood pump power supply line is passed human body skin, battery backs on the body by patient, is that blood pump is powered by external connection battery.The present invention, without the need to external power source, is that biological fuel cell is built in subcutis, without the need to through skin, can eliminate the infection that wire causes through skin;
3. be that the biological fuel cell that self-supporting energy blood pump is powered can select multiple cell power generation body serial or parallel connection according to the disclosure of invention, multiple biological fuel cell series and parallel connections can the output of battery and electric current; Anode uses the good material of electric conductivity, stability and biocompatibility to make, and as porous carbon paper, carbon cloth and non-woven fabrics etc., glucoseoxidase is coated in electrode surface; Negative electrode can use porous carbon, carbon cloth and non-woven fabrics, surface needs curing metal platinum, generally such platinum with platinum carbon mixed-powder form exist, consider be solidificated in carbon-based material top layer platinum C catalyst come off, can consider to select platinum carbon nanomaterial, directly realize the catalysis to reaction.Separate with PEM between anode and negative electrode, prevent direct contact short circuit between electrode.
Accompanying drawing explanation
Fig. 1 is self-supporting energy blood pump schematic diagram in human body.
Fig. 2 is that biological fuel cell is at operation principle schematic diagram.
Fig. 3 is the series connection schematic diagram of biological fuel cell.
Fig. 4 is the schematic diagram in parallel of biological fuel cell.
In figure: 1. human heart; 2. artificial blood vessel; 3. blood pump; 4. power line; 5. biological fuel cell; 6. negative electrode; 7. cathode catalysis layer; 8. PEM; 9. anode catalyst layer; 10. anode; 11a
1. biological fuel cell positive pole; 11b
1. biological fuel cell negative pole; 12a
1. biological fuel cell positive pole; 12b
1. biological fuel cell negative pole.
Detailed description of the invention
Self-supporting energy blood pump provided by the invention, it adopts the biological fuel cell be placed in subcutis, electrochemical reaction is there is in the glucose in tissue liquid under the catalytic action of enzyme, biological fuel cell is made to realize continuous electricity generation process, pass through the biological fuel cell serial or parallel connection of single generating again, improve output and the electric current of battery, for implanted blood pump is powered, and then realize self energizing blood pump in human body.
Below in conjunction with embodiment and accompanying drawing, the present invention is further elaborated, but does not limit the present invention.
Self-supporting energy blood pump provided by the invention, its structure as shown in Figure 1, be made up of blood pump 3, power supply line 4 and biological fuel cell 5, wherein: blood pump 3 entrance point connects the ventricle of human heart 1 by an artificial blood vessel 2, blood pump 3 port of export connects the large artery trunks of human heart 1 by another artificial blood vessel 2.Biological fuel cell 5 is implanted in subcutis, and its power line is connected with one end of power supply line 4, and the other end of power supply line 4 is connected with the power line of blood pump 3.
The power line of described power supply line 4 and biological fuel cell 5 and blood pump 3, is all arranged in human body, without the need to passing skin, thus can eliminate the infection that in current technology, power line causes through skin.
Described biological fuel cell 5, as shown in Figure 2, this battery originally as the electrode body of multiple structure, is made up of the negative electrode 6 be arranged in order, cathode catalysis layer 7, PEM 8, anode catalyst layer 9 and anode 10 its structure.The electric energy that this electrode body produces is drawn by two power supply lines, and these two power supply lines are connected with the driving power supply line of blood pump respectively.
The electrode body of described multiple structure, by its implant into body subcutaneous tissue, its operation principle is: utilize the glucose in tissue liquid and oxygen electrogenesis, the physiological characteristics of human body can the automatic renewal of realization response substrate, and the product carbon dioxide after electrochemical reaction and water also have no side effect to human body.
Described negative electrode 6 is oxygen electrodes of biological fuel cell 5, mainly utilizes the dissolved oxygen in tissue liquid; This oxygen electrode is a kind of platinum carbon electrode be made up of biocompatibility and the good porous platinum carbon Nanoalloy material of electric conductivity, porous platinum carbon Nanoalloy material not only can augmenting response time contact area, and platinum carbon electrode can realize the reduction reaction of direct catalytic oxygen, electronics, proton.
Described anode 10 is fuel electrodes of biological fuel cell 5, is made of porous materials, and this porous material comprises porous carbon, carbon felt, carbon paper and carbon fibre material etc.Due to the anode fuel mainly glucose of battery, therefore the glucose glucocorticoid dehydrogenase of the optional degraded glucose of catalyzing enzyme or glucoseoxidase or both use with together, catalyzing enzyme, by the method solidification of chemistry coating, is fixed on anode surface by anode-catalyzed enzyme.
Described PEM 8 is short-circuited to prevent the yin, yang electrode of biological fuel cell 5 from directly contacting, can use softness, proton can through material such as perfluorinated sulfonic acid class make.By the method for hot pressing, by PEM as in the middle of anode and negative electrode.The metal alloy compositions of the supporting layer of yin, yang electrode good by electric conductivity in corrosion resistance or carbon class material, consider the biocompatibility of material and the pliability of material, can adopt porous carbon cloth.
The present invention utilizes biological fuel cell to power for blood pump, biological fuel cell is arranged on subcutis, although single battery voltage and power lower, can multiple series connection or be connected in parallel power supply, utilize the feature that tissue liquid upgrades automatically, electric energy can be produced continuously, then blood pump be powered, drive blood pump, thus realize the automatic energy supply of blood pump, without the need to driving blood pump by external power supply, so just to not pass human body skin, eliminating and infecting.
The structure that multiple biological fuel cell 5 is connected as shown in Figure 3, wherein 11a
1represent the positive pole of first battery, 11b
1represent the negative pole of first battery, 11a
2represent the positive pole of second battery, 11b
2represent the negative pole of second battery, the mode of being connected in series is that the positive pole of a upper battery is connected with the negative pole of next battery, and multiple battery is linked in sequence according to this, the like.
The structure of multiple biological fuel cell 5 parallel connection as shown in Figure 4, wherein 12a
1represent the positive pole of first battery, 12b
1represent the negative pole of first battery, 12a
2represent the positive pole of second battery, 12b
2represent the negative pole of second battery, parallel be the positive pole of a upper battery, negative pole be connected with the positive pole of next battery, negative pole respectively, the like.
In the present invention: multiple biological fuel cell serial or parallel connection to obtain higher capacity and larger electric current, which kind of mode of concrete selection, can the decision of working condition needed for load, therefore, when self-supporting energy blood pump energy supply, which kind of mode biological fuel cell selects determine according to the work requirements of blood pump.
Claims (9)
1. a self-supporting energy blood pump, it is characterized in that utilizing the biological fuel cell (5) be built in human body to be blood pump (3) power supply in implant into body, blood pump (3) is without the need to external power supply, only need the feature utilizing people's in-vivo tissue liquid automatically to upgrade to produce electric energy continuously to power, realize the confession electric energy of blood pump (3), and eliminate because external power supply lead-in wire is through the infection caused by skin.
2. self-supporting energy blood pump according to claim 1, it is characterized in that blood pump (3) and biological fuel cell (5), its power line without the need to being directly connected by power supply line (4) through skin in human body, and the import and export end of blood pump (3) is respectively connected with the ventricle of human heart (1), large artery trunks respectively by an artificial blood vessel.
3. self-supporting energy blood pump according to claim 1, it is characterized in that described biological fuel cell (5) adopts the electrode body of multiple structure, be made up of the negative electrode be arranged in order (6), cathode catalysis layer (7), PEM (8), anode catalyst layer (9) and anode (10), the electric energy that this electrode body produces is drawn by two power supply lines (4), and these two power supply lines are connected with the power supply of blood pump respectively.
4. self-supporting energy blood pump according to claim 3, it is characterized in that the electrode body of described multiple structure, it utilizes glucose in tissue liquid and oxygen electrogenesis, utilize the physiological characteristics of tissue liquid to realize the automatic renewal of electrochemical reaction substrate, the by-product after electrochemical reaction is carbon dioxide to human non-toxic's side effect and water.
5. self-supporting energy blood pump according to claim 3, it is characterized in that described negative electrode (6) is the oxygen electrode of biological fuel cell (5), mainly utilize the dissolved oxygen in tissue liquid, this oxygen electrode is a kind of platinum carbon electrode be made up of biocompatibility and the good porous platinum carbon Nanoalloy material of electric conductivity.
6. self-supporting energy blood pump according to claim 3, is characterized in that described anode (10) is the fuel electrode of biological fuel cell (5), comprises porous carbon, carbon felt, carbon paper or carbon fibre material make by porous material.
7. self-supporting energy blood pump according to claim 3, it is characterized in that described PEM (8), adopt soft, proton can through the perfluorinated sulfonic acid class material that comprises make, by the method for hot pressing, PEM is placed in the centre of anode (10) and negative electrode (6).
8. self-supporting energy blood pump according to claim 3, is characterized in that described anode (10) and negative electrode (6), and its supporting layer adopts porous carbon cloth to make.
9. the self-supporting energy blood pump according to claim arbitrary in claim 1 to 8, when it is characterized in that this self-supporting energy blood pump uses, adopts multiple biological fuel cell (5) series connection or parallel way to power.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510891189.2A CN105343952A (en) | 2015-12-06 | 2015-12-06 | Blood pump achieving self-sufficient energy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510891189.2A CN105343952A (en) | 2015-12-06 | 2015-12-06 | Blood pump achieving self-sufficient energy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105343952A true CN105343952A (en) | 2016-02-24 |
Family
ID=55320103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510891189.2A Pending CN105343952A (en) | 2015-12-06 | 2015-12-06 | Blood pump achieving self-sufficient energy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105343952A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108671370A (en) * | 2018-06-20 | 2018-10-19 | 南京林业大学 | The insulin closed loop controlled release mechanisms of biological fuel cell driving |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3774243A (en) * | 1971-10-20 | 1973-11-27 | D Ng | Implantable power system for an artificial heart |
| US6342071B1 (en) * | 1999-07-08 | 2002-01-29 | Benjamin David Pless | Ambulatory blood pump |
| KR20090040797A (en) * | 2007-10-22 | 2009-04-27 | 경상대학교산학협력단 | Self-generating implantable power source |
| CN101777660A (en) * | 2010-02-04 | 2010-07-14 | 复旦大学 | Microbiological fuel cell capable of being combined with human body |
-
2015
- 2015-12-06 CN CN201510891189.2A patent/CN105343952A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3774243A (en) * | 1971-10-20 | 1973-11-27 | D Ng | Implantable power system for an artificial heart |
| US6342071B1 (en) * | 1999-07-08 | 2002-01-29 | Benjamin David Pless | Ambulatory blood pump |
| KR20090040797A (en) * | 2007-10-22 | 2009-04-27 | 경상대학교산학협력단 | Self-generating implantable power source |
| CN101777660A (en) * | 2010-02-04 | 2010-07-14 | 复旦大学 | Microbiological fuel cell capable of being combined with human body |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108671370A (en) * | 2018-06-20 | 2018-10-19 | 南京林业大学 | The insulin closed loop controlled release mechanisms of biological fuel cell driving |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Cosnier et al. | Towards glucose biofuel cells implanted in human body for powering artificial organs | |
| MacVittie et al. | A wireless transmission system powered by an enzyme biofuel cell implanted in an orange | |
| Zebda et al. | Challenges for successful implantation of biofuel cells | |
| Xu et al. | The applications and prospect of fuel cells in medical field: A review | |
| Gamella et al. | Biofuel cells–activation of micro-and macro-electronic devices | |
| El Ichi-Ribault et al. | Remote wireless control of an enzymatic biofuel cell implanted in a rabbit for 2 months | |
| Lee et al. | Totally implantable enzymatic biofuel cell and brain stimulator operating in bird through wireless communication | |
| MacVittie et al. | From “cyborg” lobsters to a pacemaker powered by implantable biofuel cells | |
| Katz et al. | Implanted biofuel cells operating in vivo–methods, applications and perspectives–feature article | |
| Sharifi et al. | Trends of biofuel cells for smart biomedical devices | |
| Shleev | Quo vadis, implanted fuel cell? | |
| Reuillard et al. | One-year stability for a glucose/oxygen biofuel cell combined with pH reactivation of the laccase/carbon nanotube biocathode | |
| Katz | Implantable biofuel cells operating in vivo—potential power sources for bioelectronic devices | |
| Reid et al. | Modeling carbon nanotube connectivity and surface activity in a contact lens biofuel cell | |
| ATE447999T1 (en) | MICRO INTEGRATED HEART PACEMAKER | |
| Ibrahim et al. | Bio‐fuel cell for medical device energy system: A review | |
| Xiao | The direct use of enzymatic biofuel cells as functional bioelectronics | |
| Singh et al. | Bio-compatible bio-fuel cells for medical devices | |
| CN109414230A (en) | For sampling the device of one or more analytes | |
| Katz | Implantable biofuel cells operating in vivo: Providing sustainable power for bioelectronic devices: From biofuel cells to cyborgs | |
| Stetten et al. | A one-compartment, direct glucose fuel cell for powering long-term medical implants | |
| CN105343952A (en) | Blood pump achieving self-sufficient energy | |
| US11660314B2 (en) | Implantable device for producing hydrogen | |
| Sharma et al. | Emerging trends in bioenergy harvesters for chronic powered implants | |
| CN109239159A (en) | A kind of pH value stimuli responsive flexibility glucose oxidase electrode and construction method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160224 |
|
| RJ01 | Rejection of invention patent application after publication |