CN105343623A - Traditional Chinese medicine formula and preparation method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine formula and preparation method of traditional Chinese medicine preparation Download PDF

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CN105343623A
CN105343623A CN201510882168.4A CN201510882168A CN105343623A CN 105343623 A CN105343623 A CN 105343623A CN 201510882168 A CN201510882168 A CN 201510882168A CN 105343623 A CN105343623 A CN 105343623A
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radix
chinese medicine
preparation
moringa
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钟华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a traditional Chinese medicine formula and a preparation method of a traditional Chinese medicine preparation, and relates to technical field of traditional Chinese medicine, particularly to the traditional Chinese medicine formula for treating diabetes and male infertility and the preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine comprises the following components: 40 g of moringa oleifera, 30 g of ginseng, 120 g of Chinese yam, 100 g of rhizoma anemarrhenae, 120 g of radix astragali, 150 g of radix trichosanthis, 120 g of poria cocos, 120 g of radix ophiopogonis, 150 g of radix rehmanniae, 150 g of cortex lycii radicis, 150 g of corn stigma, 60 g of asiatic cornelian cherry fruit and 60 g of radix glycyrrhizae. The components are matched, so that the traditional Chinese medicine preparation achieves the efficacies of treating and preventing diseases such as diabetes, male infertility and hyperlipidemia caused by diabetes, the side effect is little, the purchase cost of the raw materials is low, and the curative effect is remarkable.

Description

The preparation method of a kind of Chinese medicine formula and Chinese medicine preparation
Technical field
The present invention relates to technical field of Chinese medicines, be especially a kind ofly used for the treatment of the Chinese medicine formula of diabetes and male infertility and the preparation method of Chinese medicine preparation.
Background technology
Diabetes are metabolic diseases of a kind of multi-pathogenesis, are characterized in chronic hyperglycemia, with the metabolism disorder such as carbohydrate, fat, protein caused because of defect of insulin secretion or effect defect.And the generation of diabetes can cause the disease such as hyperlipidemia and fatty liver.In addition, along with the quickening of modern life rhythm, also there is the problems such as sterility and infertility in increasing family.
Therefore, how providing a kind of medicine that can carry out effective prevention and therapy to diabetes, hyperlipidemia and male infertility, is the technical problem that people are very concerned about.
Summary of the invention
For the deficiency that above-mentioned prior art exists, one of them object of the present invention is a kind of good effect, the Chinese medicine formula being used for the treatment of diabetes and male infertility that side effect is little, cost is low; Another object of the present invention is to provide a kind of preparation method of the Chinese medicine preparation formed based on above-mentioned Chinese medicine formula.
To achieve these goals, the present invention adopts following technical scheme:
A kind of Chinese medicine formula, described formula comprises Moringa, Radix Ginseng, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Trichosanthis, Poria, Radix Ophiopogonis, Radix Rehmanniae, Cortex Lycii, Stigma Maydis, Fructus Corni and Radix Glycyrrhizae.
Preferably, described formula be Moringa 40g, Radix Ginseng 30g, Rhizoma Dioscoreae 120g, Rhizoma Anemarrhenae 100g, Radix Astragali 120g, Radix Trichosanthis 150g, Poria 120g, Radix Ophiopogonis 120g, Radix Rehmanniae 150g, Cortex Lycii 150g, Stigma Maydis 150g, Fructus Corni 60g, Radix Glycyrrhizae 60g.
Preferably, described Moringa is one or more mixing in moringa seeds, leaf of Moringa, Moringa flower, Moringa stem.
A preparation method for Chinese medicine preparation, it comprises the following steps:
S1, Moringa is carried out dried in the environment of 50 DEG C;
S2, take Moringa 40g, Radix Ginseng 30g and Rhizoma Dioscoreae 120g and carry out mixing and pulverize as powder is to form once mixture, once mixture is decocted in water, forms a decoction liquor;
S3, by Rhizoma Anemarrhenae 100g, Radix Astragali 120g, Radix Trichosanthis 150g, Poria 120g, Radix Ophiopogonis 120g, Radix Rehmanniae 150g, Cortex Lycii 150g, Stigma Maydis 150g, Fructus Corni 60g and Radix Glycyrrhizae 60g carry out mixing and pulverize as powder is to form secondary mixture, secondary mixture is decocted in water, forms secondary decoction liquor;
S4, a decoction liquor and secondary decoction liquor to be mixed, and carry out concentration after filtration, the ratio being concentrated into medical material and concentrated solution is 3:1;
S5, in concentrated solution, add cane sugar powder and dextrin, form three mixture, carried out at 50 DEG C by three mixture in solid, shaped after drying, recycling granulation machine is processed into granule and divides collation package.
Preferably, in described step S2, by 10 times of water yields to once mixture, 1 hour is decocted to once mixture, to form a decoction liquor.
Preferably, in described step S3,0.5 hour is decocted to secondary mixture, to form secondary decoction liquor by 8 times of water yields to secondary mixture.
Owing to have employed such scheme, the property of medicine of the present invention, pharmacology and effect are as follows:
Moringa: acrid in the mouth, tepor, has to have and reduces blood glucose, improving water flood, bowel relieving and the function that enhances metabolism;
Radix Ginseng: sweet in the mouth, micro-hardship, warm in nature, there is adjustment blood pressure, recover cardiac function, treat the function such as neurasthenia and physical weakness;
Rhizoma Dioscoreae: sweet in the mouth, has spleen reinforcing nourishing the stomach, the functions such as promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission;
The Rhizoma Anemarrhenae: property bitter cold, has nourishing YIN to lower pathogenic fire, moisturizes laxation, the effect of sharp defecation;
The Radix Astragali: the sweet temperature of property, returns lung meridian, has tonifying Qi and lifting yang, function that benefit defends consolidating superficial resistance;
Radix Trichosanthis: micro-hardship is slightly cold, has the functions such as clearing away heat-fire, promoting the production of body fluid to quench thirst, evacuation of pus detumescence;
Poria: sweet in the mouth, light, property is put down, and has the functions such as promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming;
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold, there is lung moistening and clear away heart-fire, purge heat and promote the production of body fluid, the preventing or arresting vomiting that reduces phlegm, control the functions such as row water of coughing;
Radix Rehmanniae: sweetness and bitterness, cool, the function such as there is clearing away heat and promoting production of body fluid YIN nourishing, nourish blood;
Cortex Lycii: cold in nature, sweet in the mouth, has removing heat from blood except functions such as steaming, lung heat clearing pathogenic fire reducing;
Stigma Maydis: sweet in the mouth, light, property is put down, and has effect of inducing diuresis to remove edema, liver heat removing function of gallbladder promoting;
Fructus Corni:, sour-puckery flavor, slightly warm in nature, has effect of invigorating the liver and kidney hidroschesis;
Radix Glycyrrhizae: feeble QI, taste is sweet, has heat-clearing and toxic substances removing, effect of expelling phlegm for arresting cough, gastral cavity abdomen;
So, the present invention by the collocation of each constituent, can make it have treat and prevent diabetes, effect of the disease such as male infertility and the hyperlipidemia that caused by diabetes, side effect is little, and raw material acquisition cost is low, evident in efficacy.
Detailed description of the invention
Below embodiments of the invention are described in detail, but the multitude of different ways that the present invention can be defined by the claims and cover is implemented.
A kind of Chinese medicine formula being used for the treatment of diabetes and male infertility that the embodiment of the present invention provides, it mainly comprises Moringa, Radix Ginseng, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Trichosanthis, Poria, Radix Ophiopogonis, Radix Rehmanniae, Cortex Lycii, Stigma Maydis, Fructus Corni and Radix Glycyrrhizae; Wherein, take weight as proportioning: Moringa 40g, Radix Ginseng 30g, Rhizoma Dioscoreae 120g, Rhizoma Anemarrhenae 100g, Radix Astragali 120g, Radix Trichosanthis 150g, Poria 120g, Radix Ophiopogonis 120g, Radix Rehmanniae 150g, Cortex Lycii 150g, Stigma Maydis 150g, Fructus Corni 60g, Radix Glycyrrhizae 60g.
The Moringa of the present embodiment can select one or more mixing in moringa seeds, leaf of Moringa, Moringa flower, Moringa stem as the case may be.
Be used for the treatment of a preparation method for the Chinese medicine preparation of diabetes and male infertility, it comprises the following steps:
S1, Moringa is carried out dried in the environment of 50 DEG C;
S2, take Moringa 40g, Radix Ginseng 30g and Rhizoma Dioscoreae 120g and carry out mixing and pulverize as powder is to form once mixture, once mixture is decocted in water, forms a decoction liquor;
S3, by Rhizoma Anemarrhenae 100g, Radix Astragali 120g, Radix Trichosanthis 150g, Poria 120g, Radix Ophiopogonis 120g, Radix Rehmanniae 150g, Cortex Lycii 150g, Stigma Maydis 150g, Fructus Corni 60g and Radix Glycyrrhizae 60g carry out mixing and pulverize as powder is to form secondary mixture, secondary mixture is decocted in water, forms secondary decoction liquor;
S4, a decoction liquor and secondary decoction liquor to be mixed, and carry out concentration after filtration, the ratio being concentrated into medical material and concentrated solution is 3:1;
S5, in concentrated solution, add cane sugar powder and dextrin, form three mixture, carried out at 50 DEG C by three mixture in solid, shaped after drying, recycling granulation machine is processed into granule and divides collation package.
With this, by above-mentioned processing procedure, whole preparation can be made to form particulate matter, and point collation package, to enable medical personnel carry out dose distribution according to the state of an illness of sufferer, and the mouthfeel of whole preparation can be promoted by the suitable amount of sucrose powder that adds and dextrin.
For fully processing once mixture, ensure the property of medicine and the property of medicine collocation of corresponding composition, in step s 2, by 10 times of water yields to once mixture, 1 hour is decocted to once mixture, to form a decoction liquor.And in step s3, then by 8 times of water yields to secondary mixture, secondary mixture is decocted 0.5 hour, to form secondary decoction liquor.
The foregoing is only the preferred embodiments of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize the content of description of the present invention to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.

Claims (6)

1. a Chinese medicine formula, is characterized in that: described formula comprises Moringa, Radix Ginseng, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, the Radix Astragali, Radix Trichosanthis, Poria, Radix Ophiopogonis, Radix Rehmanniae, Cortex Lycii, Stigma Maydis, Fructus Corni and Radix Glycyrrhizae.
2. a kind of Chinese medicine formula as claimed in claim 1, is characterized in that: described formula be Moringa 40g, Radix Ginseng 30g, Rhizoma Dioscoreae 120g, Rhizoma Anemarrhenae 100g, Radix Astragali 120g, Radix Trichosanthis 150g, Poria 120g, Radix Ophiopogonis 120g, Radix Rehmanniae 150g, Cortex Lycii 150g, Stigma Maydis 150g, Fructus Corni 60g, Radix Glycyrrhizae 60g.
3. a kind of Chinese medicine formula being used for the treatment of diabetes and male infertility as claimed in claim 1, is characterized in that: described Moringa is one or more mixing in moringa seeds, leaf of Moringa, Moringa flower, Moringa stem.
4. a preparation method for Chinese medicine preparation, is characterized in that: it comprises the following steps:
S1, Moringa is carried out dried in the environment of 50 DEG C;
S2, take Moringa 40g, Radix Ginseng 30g and Rhizoma Dioscoreae 120g and carry out mixing and pulverize as powder is to form once mixture, once mixture is decocted in water, forms a decoction liquor;
S3, by Rhizoma Anemarrhenae 100g, Radix Astragali 120g, Radix Trichosanthis 150g, Poria 120g, Radix Ophiopogonis 120g, Radix Rehmanniae 150g, Cortex Lycii 150g, Stigma Maydis 150g, Fructus Corni 60g and Radix Glycyrrhizae 60g carry out mixing and pulverize as powder is to form secondary mixture, secondary mixture is decocted in water, forms secondary decoction liquor;
S4, a decoction liquor and secondary decoction liquor to be mixed, and carry out concentration after filtration, the ratio being concentrated into medical material and concentrated solution is 3:1;
S5, in concentrated solution, add cane sugar powder and dextrin, form three mixture, carried out at 50 DEG C by three mixture in solid, shaped after drying, recycling granulation machine is processed into granule and divides collation package.
5. the preparation method of a kind of Chinese medicine preparation as claimed in claim 4, is characterized in that: in described step S2, decocts 1 hour by 10 times of water yields to once mixture to once mixture, to form a decoction liquor.
6. the preparation method of a kind of Chinese medicine preparation as claimed in claim 5, is characterized in that: in described step S3, decocts 0.5 hour, to form secondary decoction liquor by 8 times of water yields to secondary mixture to secondary mixture.
CN201510882168.4A 2015-12-04 2015-12-04 Traditional Chinese medicine formula and preparation method of traditional Chinese medicine preparation Pending CN105343623A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107802770A (en) * 2017-11-23 2018-03-16 武汉贝贝亮生物科技有限公司 Balance the Chinese medicine and health products of metabolic system radical cure early stage type II diabetes
CN113974044A (en) * 2021-10-26 2022-01-28 康学春 Hypoglycemic solid beverage of polygonatum kingianum thirst quenching drink and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107802770A (en) * 2017-11-23 2018-03-16 武汉贝贝亮生物科技有限公司 Balance the Chinese medicine and health products of metabolic system radical cure early stage type II diabetes
CN113974044A (en) * 2021-10-26 2022-01-28 康学春 Hypoglycemic solid beverage of polygonatum kingianum thirst quenching drink and preparation method thereof

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