CN105343610A - Traditional Chinese medicine preparation for treating chloasma and method for preparing traditional Chinese medicine preparation - Google Patents

Abstract

The invention provides a traditional Chinese medicine preparation for treating chloasma and a method for preparing the traditional Chinese medicine preparation. The traditional Chinese medicine preparation comprises jasmine flowers, paramichelia baillonii, twigs and leaves of bishopwood, hance pepper stems and leaves, hawksbill turtle flesh, scandent schefflera stems and leaves, herba plumbaginis zeylanicae, silvervine fruits, duchesnea indica, vallisneria spiralls, chenopodium ambrosioides L, verbena officinalis, lignum sappan, actinolite, folium llicis cornutae, goodyera schlechtendaliana, xanthium sibiricum, rulvis glycyrrhizae extractionis sedilis, schisandra chinensis, fish maw, balanophora involucrata, elaeagnus angustifolia, corn, yellowflower toadlily herb, pipe fish and frog orchid tuber. The traditional Chinese medicine preparation and the method have the advantages that the traditional Chinese medicine preparation for chloasma can be taken safely and conveniently, is free of toxic and side effects and simple in preparation process and can become effective fast, and good treatment effects can be realized.

Description

A kind of Chinese medicine preparation for the treatment of chloasma and preparation method thereof

Technical field

The present invention relates to engineering of traditional Chinese medicine technical field, particularly relate to a kind of Chinese medicine preparation for the treatment of chloasma and preparation method thereof.

Background technology

Chloasma, the traditional Chinese medical science, also known as " chloasma hepaticum ", " sooting speckle ", is the arteriopathy dermatosis of a kind of posteriority melanin pigmentation.Skin lesion is filbert, dark brown or pitchy patch, and its boundary is clear, and edge is often not whole, and corneal ulcer as map in shape or butterfly, be symmetrically distributed in face, smooth surface, without squama, and no conscious sympton, normal and Exposure to Sunlight postemphasis.Primary disease is common in women, all can occur from adolescence to menopause.

Primary disease etiology and pathogenesis is complicated, many with liver,spleen,kidney functional disorder, steep the not normal and impairment of chong and ren channels in palace, cause qi and blood disorder, essence and blood can not go up honor and fall ill in face (deficiency syndrome) or phlegm-turbidity and blood stasis stagnant gathering in face (excess syndrome).The traditional Chinese medical science is thought, pigment mostly is stagnation of liver-QI with deficiency of the spleen, and deficiency of the liver and kindey is done, when with liver and kidney tonifying, soothing liver and strengthening spleen for controlling.Liver is the viscus of storing blood, has dredging human functional activity of vital energy, regulates the function of blood operation, like happy and dislike depressed.When the liver failing to maintain the normal flow of QI or when being in a very depressed state not easypro, then depression of liver-QI can be caused.It is not smooth that depression of liver-QI easily forms QI and blood, and the blood circulation of impact face, face is qi-blood disharmony, skin can be made intense darkness without light, long mottle.In addition, meridians are logical in human body to be passed through up and down, connects internal organs and body surface, once meridians are obstructed, will inevitably occur the symptoms such as mottle.In addition, the traditional Chinese medical science thinks that chloasma is also relevant with married woman's menses, and married woman take blood as this, blood being the material foundation of QI, and gas is the abundant of blood; Gas is sun, and blood is cloudy, blood depletion of QI being then difficult, and gas depletion of blood is then difficult raw.If suffer the evil invasion of cold menstrual period, or the product of gluttonous cold and cool raw humidogene expectorant, or feelings will is not relaxed, and abuse FENGRU SHUANG etc., all can cause visceral dysfunction, yin and yang imbalance, functional activity of QI being not smooth.The stagnation of QI is blood stasis then, cold coagulation uterus, and menses are not smooth, and stasis blocking is appointed in punching, finally causes the symptoms such as mottle.

Summary of the invention

Technical problem to be solved by this invention is, utilizes the theory of Chinese medical science that China is traditional, provides a kind of therapeutic effect good and Chinese medicine preparation of the treatment chloasma that toxic and side effects is little and preparation method thereof.

In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine preparation for the treatment of chloasma, described Chinese medicine preparation comprises following raw medicinal material: Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan, Actinolitum, Folium Ilicis Cornutae, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae, Semen setariae, Herba Tricyrtis Pilosae, Solenognathus and Radix Habenariae Delavayi.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can be preferably: Flos Jasmini Sambac 15 ~ 25 parts, Radix Polygalae Wattersii 10 ~ 20 parts, Ramulus et Folium Bischofiae Javanicae 15 ~ 30 parts, Cauliset Folium Piperis Hancei 20 ~ 30 parts, Carnis Eretmochelydis 10 ~ 25 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15 ~ 30 parts, Radix Plumbaginis Zeylanicae 20 ~ 30 parts, Semen Actinidiae Polygamae 15 ~ 25 parts, Herba Duchesneae Indicae 10 ~ 20 parts, Herba vallisneriae Spiralis 15 ~ 25 parts, Herba Strobilanthis Japonici 10 ~ 25 parts, Herba Verbenae 10 ~ 20 parts, Lignum Sappan 15 ~ 30 parts, Actinolitum 20 ~ 30 parts, Folium Ilicis Cornutae 5 ~ 15 parts, Herba goodyearae repentis 10 ~ 25 parts, Herba Xanthii 15 ~ 25 parts, Preparatum Glycyrrhizae 10 ~ 20 parts, Radix Schisandrae Bicoloris 15 ~ 30 parts, 10 ~ 25 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 10 ~ 20 parts, 20 ~ 30 parts, Fructus Elaeagni Angustifoliae, Semen setariae 15 ~ 25 parts, Herba Tricyrtis Pilosae 15 ~ 30 parts, Solenognathus 20 ~ 30 parts and Radix Habenariae Delavayi 15 ~ 25 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also more preferably: Flos Jasmini Sambac 20 ~ 25 parts, Radix Polygalae Wattersii 15 ~ 20 parts, Ramulus et Folium Bischofiae Javanicae 20 ~ 25 parts, Cauliset Folium Piperis Hancei 25 ~ 30 parts, Carnis Eretmochelydis 15 ~ 20 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 20 ~ 25 parts, Radix Plumbaginis Zeylanicae 25 ~ 30 parts, Semen Actinidiae Polygamae 15 ~ 20 parts, Herba Duchesneae Indicae 10 ~ 15 parts, Herba vallisneriae Spiralis 15 ~ 20 parts, Herba Strobilanthis Japonici 20 ~ 25 parts, Herba Verbenae 10 ~ 15 parts, Lignum Sappan 20 ~ 25 parts, Actinolitum 25 ~ 30 parts, Folium Ilicis Cornutae 5 ~ 10 parts, Herba goodyearae repentis 15 ~ 20 parts, Herba Xanthii 20 ~ 25 parts, Preparatum Glycyrrhizae 15 ~ 20 parts, Radix Schisandrae Bicoloris 15 ~ 25 parts, 20 ~ 25 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 15 ~ 20 parts, 25 ~ 30 parts, Fructus Elaeagni Angustifoliae, Semen setariae 20 ~ 25 parts, Herba Tricyrtis Pilosae 15 ~ 20 parts, Solenognathus 20 ~ 25 parts and Radix Habenariae Delavayi 15 ~ 20 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation also can more preferably: Flos Jasmini Sambac 22 parts, Radix Polygalae Wattersii 19 parts, Ramulus et Folium Bischofiae Javanicae 21 parts, Cauliset Folium Piperis Hancei 28 parts, Carnis Eretmochelydis 16 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 24 parts, Radix Plumbaginis Zeylanicae 26 parts, Semen Actinidiae Polygamae 18 parts, Herba Duchesneae Indicae 12 parts, Herba vallisneriae Spiralis 19 parts, Herba Strobilanthis Japonici 21 parts, Herba Verbenae 15 parts, Lignum Sappan 21 parts, Actinolitum 29 parts, Folium Ilicis Cornutae 7 parts, Herba goodyearae repentis 18 parts, Herba Xanthii 21 parts, Preparatum Glycyrrhizae 19 parts, Radix Schisandrae Bicoloris 16 parts, 24 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 16 parts, 28 parts, Fructus Elaeagni Angustifoliae, Semen setariae 22 parts, Herba Tricyrtis Pilosae 19 parts, Solenognathus 21 parts and Radix Habenariae Delavayi 19 parts.

When the dosage form of described Chinese medicine preparation is tablet, its preparation method comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan and Actinolitum mixing, add relative to mixture 3 times ~ 5 times amount determining alcohol be 55% ~ 65% alcohol reflux 2 times ~ 4 times, each 2 hours ~ 3 hours, filter, filtrate merges, and reclaims ethanol, being concentrated into 70 DEG C of relative densities is the mastic of 1.30 ~ 1.32, for subsequent use;

All the other raw medicinal materials are mixed in proportion by second step, add relative to mixture 3 ~ 5 times of water gagings, boil 2 ~ 4 hours, and filter, being concentrated into 70 DEG C of relative densities is the mastic of 1.27 ~ 1.29;

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C ~ 65 DEG C reduced vacuum dryings, get dry extract powder;

4th step, carries out mixing by described dried cream powder and starch and processes, obtain mastic mixture; Described mastic and the weight ratio of starch are 1: 0.01 ~ 0.02; Described mastic mixture is carried out pelletization treatment, dried, the mastic compound particles obtained;

5th step, described mastic compound particles and Pulvis Talci, magnesium stearate are carried out successively mixing processes, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product; The weight ratio of described granule, Pulvis Talci, magnesium stearate is 100: 1 ~ 3: 0.15 ~ 0.3.

When the dosage form of described Chinese medicine preparation is syrup, its preparation method comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) and Radix Plumbaginis Zeylanicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,

Second step, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae and Semen setariae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;

3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;

4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.

Beneficial effect of the present invention: the Chinese medicine preparation that chloasma of the present invention uses is safe and convenient to use, have no side effect, instant effect, therapeutic effect is good, and preparation technology is simple.

Detailed description of the invention

The invention provides a kind of Chinese medicine preparation for the treatment of chloasma, Chinese medicine preparation comprises following raw medicinal material: Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan, Actinolitum, Folium Ilicis Cornutae, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae, Semen setariae, Herba Tricyrtis Pilosae, Solenognathus and Radix Habenariae Delavayi.

The pharmacology of various raw medicinal material is as follows:

Flos Jasmini Sambac: [another name] Bai Moli; little Nan is strong; How to spend; Rosary China, last pear flower.[source] medical material Ji Yuan: be the flower of Oleaceae plants jasmine.[nature and flavor] are pungent; Micro-sweet; Warm in nature.[return through] spleen; Stomach; Liver Channel.[function cures mainly] regulating QI to relieve pain; Ward off dirty dissipating depression of QI.Hinder in main wet method; Chest and diaphragm does not relax; Dysentery is suffered from abdominal pain; Dizziness headache; Conjunctival congestion; Sore.[each discussion] 1. " book on Chinese herbal medicine is new again ": can clear asthenic fire, and cold removing amasss, and controls sore, the cellulitis that disappears tumor.2. " occupy diet spectrum with breath ": regulating middle-JIAO and making the adverse QI downward, ward off foul.Control the inferior dysentery stomachache.3. " decoction pieces is newly joined ": suppressing the hyperactive liver resolving depression, regulating QI to relieve pain.[extracts] " China's book on Chinese herbal medicine "

Radix Polygalae Wattersii: [another name] wooden Fructus Capsici, Radix Euonymi japonici, smelly skin.[source] medical material Ji Yuan: be the Herb of Pittosporaceae plant shortcalyx pittosporum herb.[nature and flavor] are micro-sweet puckery; Temperature.[return through] Liver Channel [function cures mainly] promoting blood circulation and detoxication.Main mastalgia; Toxic swelling.[each discussion] 1. " register planted by Guangxi medicine ": bark: strengthening by means of tonics, medicine powder for relaxing muscle blood.Control traumatic injury.2. Nanchuan " conventional Chinese herbal medicine handbook ": root, leaf: promoting blood circulation and detoxication.Control acute mastitis.[extracts] " China's book on Chinese herbal medicine "

Ramulus et Folium Bischofiae Javanicae: [another name] autumn wind, water balk, SANYE are red, duck foot maple, a thousand pieces of gold do not fall, Ramulus et Folium Claoxyli, harvest season in autumn maple, cross winter pear, Bischofia polycarpa.[source] medical material Ji Yuan: be root, the bark of euphorbia plant Ramulus et Folium Bischofiae Javanicae.[nature and flavor] acrid in the mouth; Puckery; Cool in nature.[return through] heart channel.[function cures mainly] expelling wind and removing dampness; Blood stasis dispelling removing food stagnancy.Main rheumatic ostalgia; Dysphagic; Regurgitation; Dysentery.[each discussion] be " Luchuan book on Chinese herbal medicine " 1.: branch and leaf and skin: wind dispelling, invigorates blood circulation, detumescence.Dispelling the wind and dampness pathogens osteodynia.2. " Quanzhou book on Chinese herbal medicine ": leaf: promoting flow of QI and blood, detumescence relieves internal heat.Control QI and blood pent-up, ulcer sores.[extracts] " China's book on Chinese herbal medicine "

Cauliset Folium Piperis Hancei: [source] medical material Ji Yuan: be stem and leaf or the root of Piperaceae plant Cauliset Folium Piperis Hancei.[nature and flavor] are pungent; Temperature.[return through] lung; Spleen channel.[function cures mainly] expelling wind and removing dampness; Promoting blood circulation and detumescence; Promoting the circulation of QI to relieve pain; Preventing phlegm from forming and stopping coughing.Main air pain of dampness syndrome; Stomachache; Dysmenorrhea; Traumatic injury; Wind and cold cough with asthma; Colicky.[each discussion] " Guangxi Chinese herbal medicine ": dispelling the wind and dampness pathogens osteodynia, paralysis of the limbs, cold, cough and asthma, the cold pain of abdomen." the practical Chinese herbal medicine in Guangxi newly selects ": reducing swelling and alleviating pain, wind dispelling is trembled with fear, and stimulates the menstrual flow.Control traumatic injury, venom.[extracts] " China's book on Chinese herbal medicine "

Carnis Eretmochelydis: [source] medical material Ji Yuan: be the meat of Cheloniidae animal Carapax Eretmochelydis.[nature and flavor] sweet in the mouth; Property is put down; [return through] heart; Lung; Liver Channel.[function cures mainly] dispels the wind expectorant; Promoting flow of QI and blood.Main cough with copious phlegm; Menoxenia.[each discussion] " feeding habits book on Chinese herbal medicine ": main all pathogenic wind toxic, qi and blood circulation promotion, removes wind-phlegm in chest and diaphragm, relieving palpitation god, by pathogenic heat, sharp intestine and small intestine, logical married woman's passages through which vital energy circulates.[extracts] " China's book on Chinese herbal medicine "

Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae): [another name] lobule Cortex schefflerae octophyllae, Radix Schefflerae Arboricolae, seven leaves are rotten, Canis familiaris L. foot is crowed, hands tree, seven Cortex Acanthopanacis Radicis, seven leaf rattans.[source] medical material Ji Yuan: be root or the stem and leaf of Araliaceae schefflera arboricola.[nature and flavor] acrid in the mouth; Micro-hardship; Warm in nature.[function cures mainly] wind-expelling pain-stopping; Promoting blood circulation and detumescence.Main air shows arthralgia pain; Headache; Toothache; Epigastric pain; Dysmenorrhea; Puerperal abdonimal pain; Treating swelling and pain by traumatic injury; Fracture; Skin ulcer swells.[each discussion] " the practical Chinese herbal medicine in Guangxi newly selects ": promoting the circulation of QI to relieve pain, promoting blood circulation and detumescence, strengthening bone and muscle.Control acute rheumatic arthritis, stomachache, fracture, bruise, lumbago and skelalgia, paralysis.[extracts] " China's book on Chinese herbal medicine "

Radix Plumbaginis Zeylanicae: [source] medical material Ji Yuan: be herb or the root of Plumbaginaceae plant Radix Plumbaginis Zeylanicae.[nature and flavor] are pungent; Bitter; Puckery; Property wets.[function cures mainly] expelling wind and removing dampness; Promoting flow of QI and blood; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Heart peratodynia; Hepatosplenomegaly; Blood stasis amenorrhea; Osteopatia sprain; Carbuncle scrofula; Scabies pruritus; Venom.[each discussion] be " the SHENGCAO property of medicine is standby to be wanted " 1.: loose skin ulcer, detumescence, dispels the wind.Control Serpentis to sting, dysentery disease, removes eye mask, descends tear windward; Wipe tinea mange, detoxification is all wonderful.2. " south of the Five Ridges gather medicinal herbs record ": its leaf mashes deposited traumatic injury wound, can blood stasis removing.3. Guangzhou army " conventional Chinese herbal medicine handbook ": expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling.Root: dispelling the wind and dampness pathogens osteodynia, old articular sprain, heart peratodynia.[extracts] " China's book on Chinese herbal medicine "

Semen Actinidiae Polygamae: [source] medical material Ji Yuan: for Actinidiaceae plant Ramulus et Folium Actinidiae Polygamae is with the fruit of insect gall.[nature and flavor] are pungent; Bitter; Warm in nature.[return through] liver; Kidney channel.[function cures mainly] dispelling wind and removing obstruction in the collateral; Blood-activating and qi-promoting; Dispersing cold for relieving pain.Tuyere line in master tiltedly; Mass beside the umbilicus is suffered from abdominal pain; Hernia [each discussion] is 1. " property of medicine opinion ": control middle harmful wind, and actinal surface Wai is oblique, main cold mass beside the umbilicus air parcel, woman's asthenia.2. " modern Practical Chinese medicinal ": the effect having warm health, for lumbago colic.[extracts] " China's book on Chinese herbal medicine "

Herba Duchesneae Indicae: [source] medical material Ji Yuan: be the herb of rosaceous plant Herba Duchesneae Indicae.[nature and flavor] are sweet, bitter; Cold.[return through] lung; Liver; Large intestine channel.[function cures mainly] heat-clearing and toxic substances removing; Dissipating blood stasis Xiao swells; Cooling blood for hemostasis.Main calentura; Infantile convulsion; Cough; Spit blood; Laryngopharynx swelling and pain; Dysentery; Carbuncle; Furuncle; Snake bite and insect sting; Scald; Flu; Jaundice; Conjunctival congestion; Aphtha; Mumps; Furuncle and phyma; Metrorrhagia; Menoxenia; Treating swelling and pain by traumatic injury.[extracts] " China's book on Chinese herbal medicine "

Herba vallisneriae Spiralis: [another name] is with foot Caulis et Folium Polygalae Tenuifoliae, little knotweed, flat grass, Folium Allii tuberosi grass, noodles are careless, water Seedling, belt are pricked, frogbit Herba vallisneriae Spiralis.[source] medical material Ji Yuan: be the herb of Hydrocharctaceae plant Herba vallisneriae Spiralis.[nature and flavor] bitter in the mouth; Warm in nature.[return through] returns spleen, Liver Channel.[function cures mainly] dampness leukorrhagia stopping; Promoting flow of QI and blood.Under master tape, color is white; Prolonged lochia.[each discussion] " herbal classic is met former ": the blood in regulating the flow of vital energy, decoction in puerperal, can by lochia.[extracts] " China's book on Chinese herbal medicine "

Herba Strobilanthis Japonici: [another name] bright and beautiful mountain, water are even called together, pool, mountain is blue.[source] medical material Ji Yuan: for acanthaceous plant hangs down the herb of sequence Acanthaceous indigo.[nature and flavor] acrid in the mouth; Micro-hardship; Property micro-wet.[return through] returns liver; Spleen channel.[function cures mainly] promoting blood circulation to restore menstrual flow; Blood stasis dispelling row water.Main menoxenia; Dysmenorrhea; Amenorrhea; Puerperal abdonimal pain; Lump in the abdomen; Body and face edema; Carbuncle; Swell and play damage.[each discussion] " Chinese herbal medicine is commonly used in Sichuan ": the capable water of repercussive, soothing liver-QI falls apart strongly fragrant.Control menoxenia, puerperal dripping stomachache, bruise, lump in the abdomen carbuncle, traumatic injury and body and face edema.[extracts] " China's book on Chinese herbal medicine "

Herba Verbenae: [source] this product is the dry aerial parts of Verbenaceae Herba Verbenae.[nature and flavor] are bitter, cool.[return through] returns liver, spleen channel.[function cures mainly] promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, removing toxic substances, inducing diuresis to remove edema.For lump in the abdomen, amenorrhea dysmenorrhea, malaria, sore throat, carbuncle, edema, pyretic stranguria.[extracts] " Chinese Pharmacopoeia "

Lignum Sappan: [another name] lignum sappan.[source] this product is the dry duramen of pulse family Caesalpinia Lignum Sappan.[nature and flavor] are sweet, salty, flat.[return through] GUIXIN, liver, spleen channel.[function cures mainly] promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.For amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, wound swells and ache.[extracts] " Chinese Pharmacopoeia "

Actinolitum: [another name] Bai Shi, sheep play stone, Shi Sheng, positive stone, Actinolitum.[source] medical material Ji Yuan: be the silicates amphibole tremolite and xenogenesis tremolite asbestos thereof.[nature and flavor] are salty; Temperature.[return through] kidney channel.[function cures mainly] warming the kidney to invigorate YANG.Main kidney yang deficiency; The cold numbness of waist knee joint; Impotence in male; Woman's cold womb; Lump in the abdomen metrorrhagia.[each discussion] 1. " herbal classic ": main metrorrhagia and metrostaxis, the dirty middle blood of broken son, and lump in the abdomen stagnation of QI, cold and heat are suffered from abdominal pain, and impotence does not rise, tonifying for the deficiency.2. " property of medicine opinion ": the kidney invigorating gas essence is weary, and pain in the lumbar region knee joint is cold, arthralgia chiefly caused by damp pathogen, it is cold for a long time to warm up woman uterus, and cold disease is trembled with fear abdominal mass, and only moon water is indefinite.3. " detailed outline ": loose all heat swells.4. " Bencao Jingshu ": Actinolitum, subsidy yang-energy, and being detained the panacea of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels except long-pending cold stagnated blood, therefore can main metrorrhagia and metrostaxis, and the dirty middle mass formed by blood stasis abdominal mass stagnation of QI of broken son, cold and heat are suffered from abdominal pain, and man's stem head is trembled with fear, and impotence does not rise, and uncontrolled urination is itched.Kidney-Yang foot, then QI of five ZANG-organs is exuberant, and evil wet gas falls apart outward, therefore and deodorizes antiperspirant also." not Lu " main consumer edema person again, lid refers to kidney-yangly return unit, then can warm up the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels and fumigate waste matter, change precise and tiny, help spleen soil with controlling the water circulation also.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "

Folium Ilicis Cornutae: [another name] Folium Mahoniae, Cornu Caprae seu Ovis thorn, Radix Ilicis Pernyi, Ilex pernyi, hexagonal tea, hexagonal thorn, anistree thorn, Ramulus Kalopanacis seu Araliae, E Zhang le, Folium Ilicis.[source] this product is the dried leaves of holly plant Ilex cornuta Lindl..[nature and flavor] are bitter, cool.[return through] returns liver, kidney channel.[function cures mainly] clearing away heat and nourishing YIN, suppressing the hyperactive liver, kidney tonifying.For pulmonary tuberculosis spitting of blood, osteopyrexia and fever, has a dizzy spell; Hypertension.[extracts] " Chinese Pharmacopoeia "

Herba goodyearae repentis: [another name] silver-colored line basin, nine layers of lid, Radix primulae sinodenticulatae, little general, lobule is blue or green, Folium Cannabis is blue or green, Trimeresurus stejnegeri, Agkistrodon medicine, sharp leaf mountain butterfly, the little green grass or young crops of Folium Bambusae, lung hornwart, Rhizoma pinelliae cordatae, Oxyria sinensis Hemsl., silver earring.[source] medical material Ji Yuan: be the herb of the large Herba goodyearae repentis of orchid, little Herba goodyearae repentis, greatly piebaldism orchid or floss tikka aspidistra.[nature and flavor] are sweet; Pungent; Flat.[function cures mainly] nourishing the lung to arrest cough; Tonify Qi of the kidney; Promoting flow of QI and blood; Subduing swelling and detoxicating.Main pulmonary tuberculosis cough; Tracheitis; Dizzy weak; Neurasthenia; Sexual impotence; Traumatic injury; Arthralgia; Laryngopharynx swelling and pain; Acute mastitis; Furuncle; Scrofula; Venom.[each discussion] " Zhejiang conventional medical herbs among the people ": heat-clearing and toxic substances removing, antiinflammatory detumescent.Control venom, carbuncle furuncle, pneumonopathy is coughed, tracheitis." Chinese herbal medicine is commonly used in Tibet ": hard masses softening and resolving.Control scrofula.[extracts] " China's book on Chinese herbal medicine "

Herba Xanthii: [source] medical material Ji Yuan: be the herb of feverfew Herba Xanthii or Herba Xanthii mongolici.[nature and flavor] bitter in the mouth; Pungent; Cold nature.[return through] returns lung; Spleen; Liver Channel.[function cures mainly] dispels the wind; Heat radiation; Dehumidifying; Removing toxic substances.Main flu; Wind syndrome of head; Dizzy; Nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery.[each discussion] be 《 Lv Cliff rock book on Chinese herbal medicine 1. ": go wind to invigorate blood circulation.2. " Tian Bao book on Chinese herbal medicine ": go wind to detoxify.Control the large blue veins of tripe, skin pruritus, rheumatism.3. " Guangdong Chinese medicine ": control blood tinea, phlegm-fire core, flu, nasal sinusitis.[extracts] " China's book on Chinese herbal medicine "

Preparatum Glycyrrhizae: [another name] Radix Glycyrrhizae is yellow, Gan Zhonghuang.[source] medical material Ji Yuan: for Radix Glycyrrhizae powder is put in bamboo coin cylinder, flood the manufactured goods after certain hour in people manure pit.[nature and flavor] sweet in the mouth; Salty; Cold in nature.[return through] heart; Stomach warp.[function cures mainly] clearing away heat and cooling blood; Eliminating fire and detoxication.The capable calentura in main sky; Epidemic febrile disease sends out speckle; Large hot excessive thirst; Variola heat in blood; Erysipelas; Skin infection [each discussion] is 1. " Bencao Jingshu ": separate stomach man pyretic toxicity.2. essentials of Matea Medica: purge heat, clearing away phlegm fire, helps digestion long-pending, the five internal organs excess-heat of having a bowel movement.Control sky capable fanatical, variola heat in blood, blackly can not fall into.3. " herbal classic is met former ": Xie Tian is capable fanatic, maculae caused by violent heat pathogen.4. " book on Chinese herbal medicine is looked for the truth ": Preparatum Glycyrrhizae.Book carries merit and specially enters stomach removing toxic substances, with its sweet in the mouth therefore also.It separates the five internal organs excess-heat, cold therefore also with its gas.[extracts] " China's book on Chinese herbal medicine "

Radix Schisandrae Bicoloris: [another name] fragrant Fructus Perillae, Radix Schisandrae Bicoloris.[source] medical material Ji Yuan: be root, the rattan of Schisandraceae Plant two color Fructus Schisandrae Chinensis.[nature and flavor] are bitter; Puckery; Warm in nature.[return through] liver; Stomach warp.[function cures mainly] dredge the meridian passage; Spleen benefiting and stimulating the appetite.Main impairment caused by overstrain takes off power; Extremity are tingle; Breast is vexed; Indigestion and loss of appetite.[extracts] " China's book on Chinese herbal medicine "

Air Bladder pseudosciaenae seu Acipenser: [another name] Zhu Yi, Zhu Anchovy, roe, fish glue, fish glue, white fish glue, fish bladder, Xuan glue, fish maw.[source] medical material Ji Yuan: be the Air Bladder pseudosciaenae seu Acipenser of Sciaenidae animal Carnis Pseudosciaenae, Carnis Pseudosciaenae, Nibea albiflora or Acipenseridae animal mandarin sturgeon, sturgeon etc.[nature and flavor] sweet in the mouth; Property is put down.[return through] kidney; Liver Channel.[function cures mainly] invigorating the liver and kidney; Nourishing blood and hemoslasis; Dissipating blood stasis for subsidence of swelling.Main emission due to deficiency of the kidney; Weakness of the waist and knees; Lumbago; Vertigo and tinnitus; Leucorrhea; Habitual abortion; Ischemic spasm; Puerperal puerperal tetanus; Tetanus; Epilepsy; Aplastic anemia; Spit blood; Hematuria; Metrorrhagia; Traumatic hemorrhage; Carbuncle of yin nature; Fistula; Chronic ulcer; Chap; Gout; Hemorrhoid.[each discussion] 1. supplement to the Herbal: incarnation is prolonged does not go out person for main bamboo wood, and get four limits in white deposited skin ulcer, namely meat is rotten goes out thorn.2. Compendium of Material Medica: fish glue, only injured blood goes out incessantly; Bladder glue, charred medicinal herb with its property retained, control married woman difficult labour, puerperal tetany caused by wind pathogen, tetanus convulsion, preventing or arresting vomiting blood, dissipating blood stasis blood, detumescence poison.3. " book on Chinese herbal medicine is newly organized ": mend lean blood.4. " book on Chinese herbal medicine asks former ": nourishing muscle and tendon arteries and veins, determine hands war, controlling nocturnal emission with astringent drugs.[extracts] " China's book on Chinese herbal medicine "

Balanophora dioica R Br ex Royle: [another name] does not go up lotus, exceedingly high wax candle, Shi Shanglian, mountain Fructus Ananadis comosi.[source] medical material Ji Yuan: be the Herb of Balanophoraceae plant flower thinning Balaenoptera borealis Lesson.[nature and flavor] are bitter; Cool in nature.The yin nourishing of [function cures mainly] kidney tonifying; Clearing away heat to stop bleeding.Main lumbago due to renal deficiency; Asthenia is hemorrhage; Bleeding hemorrhoids.[extracts] " China's book on Chinese herbal medicine "

Fructus Elaeagni Angustifoliae: [another name] four taste fruit, Semen Phaseoli, gigue reach.[source] medical material Ji Yuan: be the mature fruit of Elaeangnaceae plant Fructus Elaeagni Angustifoliae, east Fructus Elaeagni Angustifoliae and point fruit Fructus Elaeagni Angustifoliae.[nature and flavor] sour in the mouth; Micro-sweet; Cool in nature.[return through] lung; Liver; Spleen; Stomach; Kidney channel.[function cures mainly] liver-nourishing kidney-boosting; Spleen invigorating regulating menstruation.Main deficiency of the liver is dizzy; Lumbago due to renal deficiency; Insufficiency of the spleen diarrhoea; Dyspepsia; Leukorrhagia; Menoxenia.[each discussion] " Chinese Herbal Medicine in Xinjiang handbook ": strong, calm, controlling nocturnal emission with astringent drugs, stomach invigorating, antidiarrheal, regulating menstruation, diuresis.Treat for stomachache, diarrhoea, physical weakness, cough due to lung-heat.[extracts] " China's book on Chinese herbal medicine "

Semen setariae: [another name] white fine strain of millet foxtail millet, sacrifical grain in ancient times rice, foxtail millet paddy, Semen setariae, hard foxtail millet, Xian foxtail millet, millet, cold foxtail millet, Huang Su, Semen setariae.[source] medical material Ji Yuan: be the kernel of grass fine strain of millet or foxtail millet.It stores the old Semen setariae of old person's name of a specified duration, sacrifical grain in ancient times.[nature and flavor] sweet in the mouth; Salty; Cool in nature; [return through] kidney; Spleen; Stomach warp.[function cures mainly] and middle kidney tonifying; Heat extraction; Removing toxic substances.Main taste deficiency-heat; Regurgitation is vomitted; Abdominal distention lack of appetite; Quench one's thirst; Dysentery; Burn and scald.[each discussion] 1. " not Lu ": mainly support kidney qi, go heat in stomach spleen, QI invigorating.2. old Semen setariae: main gastric heat, quenches one's thirst, diuresis.3. supplement to the Herbal: all poison of corn flour solution, water stirs and takes it; Also main heat stomachache, epistaxis, and decocting in water takes it.4. " daily book on Chinese herbal medicine ": with middle QI invigorating, dysentery relieving, controls and quench one's thirst, diuresis, and old person is better.5. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": main YIN nourishing, support kidney qi, strengthening the spleen and stomach, in warm.Control regurgitation, Pediatric Liver worm, or cholera is vomited and diarrhoea, tripe pain dysentery, watery diarrhea is more than.6. " detailed outline ": food benefiting pubic region of cooking congee, tonifying deficiency, opens the intestines and stomach.[extracts] " China's book on Chinese herbal medicine "

Herba Tricyrtis Pilosae: [another name] founds bamboo root, Radix Tricyrtidis pilosae, Fructus Cucumidis sativi dish, Cucumber perfume, melon rice dish.[source] medical material Ji Yuan: be the herb of liliaceous plant Hemerocallis citrina Baroni Herba Tricyrtidis macropodae.[nature and flavor] are sweet; Cold nature.[function cures mainly] clearing heat and relieving fidgetness; Promoting blood circulation and detumescence.Main gastric heat is thirsty; Dysphoria; Impairment caused by overstrain; Edema.[each discussion] " Traditional Chinese Medicine in Sichuan will ": control the whole body and swell, sun stroke pain due to disorder of QI, thermal man's pericardium and rubella pruritus.[extracts] " China's book on Chinese herbal medicine "

Solenognathus: [another name] pipefish, cash strings.[source] this product is the dry body of Syngnathidae animal solenognathus hardwickii, syngnathoides biaculeatus or syngnathus acus Linnaeus.[nature and flavor] are sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] warming the kidney to invigorate YANG, mass dissipating and swelling eliminating.For impotence and seminal emission, lump in the abdomen, scrofula sucutaneous nodule, injury from falling down; External treatment carbuncle furuncle.[extracts] " Chinese Pharmacopoeia "

Radix Habenariae Delavayi: [another name] Radix Satyrii nepalensis, Kunming two aspidistra, twoflower rattlesnake plantain, pairing grass, egg seven, great Ye Pseudobulbus Bletillae (Rhizoma Bletillae).[source] medical material Ji Yuan: be the tuber of the beautiful phoenix flower of the thick lobe of orchid.[nature and flavor] are sweet; Micro-pungent; Temperature.[return through] kidney channel.[function cures mainly] replenishing kidney, strengthening waist; Regulating QI to relieve pain.Main lumbago due to renal deficiency; Hernia; The stagnation of QI is had a stomachache.[extracts] " China's book on Chinese herbal medicine "

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can more preferably: Flos Jasmini Sambac 15 ~ 25 parts, Radix Polygalae Wattersii 10 ~ 20 parts, Ramulus et Folium Bischofiae Javanicae 15 ~ 30 parts, Cauliset Folium Piperis Hancei 20 ~ 30 parts, Carnis Eretmochelydis 10 ~ 25 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15 ~ 30 parts, Radix Plumbaginis Zeylanicae 20 ~ 30 parts, Semen Actinidiae Polygamae 15 ~ 25 parts, Herba Duchesneae Indicae 10 ~ 20 parts, Herba vallisneriae Spiralis 15 ~ 25 parts, Herba Strobilanthis Japonici 10 ~ 25 parts, Herba Verbenae 10 ~ 20 parts, Lignum Sappan 15 ~ 30 parts, Actinolitum 20 ~ 30 parts, Folium Ilicis Cornutae 5 ~ 15 parts, Herba goodyearae repentis 10 ~ 25 parts, Herba Xanthii 15 ~ 25 parts, Preparatum Glycyrrhizae 10 ~ 20 parts, Radix Schisandrae Bicoloris 15 ~ 30 parts, 10 ~ 25 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 10 ~ 20 parts, 20 ~ 30 parts, Fructus Elaeagni Angustifoliae, Semen setariae 15 ~ 25 parts, Herba Tricyrtis Pilosae 15 ~ 30 parts, Solenognathus 20 ~ 30 parts and Radix Habenariae Delavayi 15 ~ 25 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also more preferably: Flos Jasmini Sambac 20 ~ 25 parts, Radix Polygalae Wattersii 15 ~ 20 parts, Ramulus et Folium Bischofiae Javanicae 20 ~ 25 parts, Cauliset Folium Piperis Hancei 25 ~ 30 parts, Carnis Eretmochelydis 15 ~ 20 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 20 ~ 25 parts, Radix Plumbaginis Zeylanicae 25 ~ 30 parts, Semen Actinidiae Polygamae 15 ~ 20 parts, Herba Duchesneae Indicae 10 ~ 15 parts, Herba vallisneriae Spiralis 15 ~ 20 parts, Herba Strobilanthis Japonici 20 ~ 25 parts, Herba Verbenae 10 ~ 15 parts, Lignum Sappan 20 ~ 25 parts, Actinolitum 25 ~ 30 parts, Folium Ilicis Cornutae 5 ~ 10 parts, Herba goodyearae repentis 15 ~ 20 parts, Herba Xanthii 20 ~ 25 parts, Preparatum Glycyrrhizae 15 ~ 20 parts, Radix Schisandrae Bicoloris 15 ~ 25 parts, 20 ~ 25 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 15 ~ 20 parts, 25 ~ 30 parts, Fructus Elaeagni Angustifoliae, Semen setariae 20 ~ 25 parts, Herba Tricyrtis Pilosae 15 ~ 20 parts, Solenognathus 20 ~ 25 parts and Radix Habenariae Delavayi 15 ~ 20 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation also can more preferably: Flos Jasmini Sambac 22 parts, Radix Polygalae Wattersii 19 parts, Ramulus et Folium Bischofiae Javanicae 21 parts, Cauliset Folium Piperis Hancei 28 parts, Carnis Eretmochelydis 16 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 24 parts, Radix Plumbaginis Zeylanicae 26 parts, Semen Actinidiae Polygamae 18 parts, Herba Duchesneae Indicae 12 parts, Herba vallisneriae Spiralis 19 parts, Herba Strobilanthis Japonici 21 parts, Herba Verbenae 15 parts, Lignum Sappan 21 parts, Actinolitum 29 parts, Folium Ilicis Cornutae 7 parts, Herba goodyearae repentis 18 parts, Herba Xanthii 21 parts, Preparatum Glycyrrhizae 19 parts, Radix Schisandrae Bicoloris 16 parts, 24 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 16 parts, 28 parts, Fructus Elaeagni Angustifoliae, Semen setariae 22 parts, Herba Tricyrtis Pilosae 19 parts, Solenognathus 21 parts and Radix Habenariae Delavayi 19 parts.

The present invention further provides again a kind of preparation method of Chinese medicine preparation of above-mentioned treatment chloasma, and the dosage form of described Chinese medicine preparation is tablet, and it comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan and Actinolitum mixing, add relative to mixture 3 times ~ 5 times amount determining alcohol be 55% ~ 65% alcohol reflux 2 times ~ 4 times, each 2 hours ~ 3 hours, filter, filtrate merges, and reclaims ethanol, being concentrated into 70 DEG C of relative densities is the mastic of 1.30 ~ 1.32, for subsequent use;

All the other raw medicinal materials are mixed in proportion by second step, add relative to mixture 3 ~ 5 times of water gagings, boil 2 ~ 4 hours, and filter, being concentrated into 70 DEG C of relative densities is the mastic of 1.27 ~ 1.29;

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C ~ 65 DEG C reduced vacuum dryings, get dry extract powder;

4th step, carries out mixing by described dried cream powder and starch and processes, obtain mastic mixture; Described mastic and the weight ratio of starch are 1: 0.01 ~ 0.02; Described mastic mixture is carried out pelletization treatment, dried, the mastic compound particles obtained;

5th step, described mastic compound particles and Pulvis Talci, magnesium stearate are carried out successively mixing processes, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product; The weight ratio of described granule, Pulvis Talci, magnesium stearate is 100: 1 ~ 3: 0.15 ~ 0.3.

The present invention further provides again a kind of preparation method of Chinese medicine preparation of above-mentioned treatment chloasma, and the dosage form of described Chinese medicine preparation is syrup, and it comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) and Radix Plumbaginis Zeylanicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,

Second step, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae and Semen setariae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;

3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;

4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1: tablet prepared by the present invention

Get Flos Jasmini Sambac 220g, Radix Polygalae Wattersii 190g, Ramulus et Folium Bischofiae Javanicae 210g, Cauliset Folium Piperis Hancei 280g, Carnis Eretmochelydis 160g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 240g, Radix Plumbaginis Zeylanicae 260g, Semen Actinidiae Polygamae 180g, Herba Duchesneae Indicae 120g, Herba vallisneriae Spiralis 190g, Herba Strobilanthis Japonici 210g, Herba Verbenae 150g, Lignum Sappan 210g, Actinolitum 290g, Folium Ilicis Cornutae 70g, Herba goodyearae repentis 180g, Herba Xanthii 210g, Preparatum Glycyrrhizae 190g, Radix Schisandrae Bicoloris 160g, Air Bladder pseudosciaenae seu Acipenser 240g, Balanophora dioica R Br ex Royle 160g, Fructus Elaeagni Angustifoliae 280g, Semen setariae 220g, Herba Tricyrtis Pilosae 190g, Solenognathus 210g and Radix Habenariae Delavayi 190g.

Its preparation method comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan and Actinolitum mixing, add relative to mixture 5 times amount determining alcohol be 60% alcohol reflux 3 times, each 2 hours, filter, filtrate merges, and reclaims ethanol, being concentrated into 70 DEG C of relative densities is the mastic of 1.32, for subsequent use;

All the other raw medicinal materials are mixed in proportion by second step, add relative to mixture 5 times of water gagings, boil 3 hours, and filter, being concentrated into 70 DEG C of relative densities is the mastic of 1.28;

3rd step, the mastic mixing that the first step, second step are obtained, 65 DEG C of reduced vacuum dryings, get dry extract powder;

4th step, carries out mixing by described dried cream powder and starch and processes, obtain mastic mixture; Described mastic and the weight ratio of starch are 1: 0.015; Described mastic mixture is carried out pelletization treatment, dried, the mastic compound particles obtained;

5th step, described mastic compound particles and Pulvis Talci, magnesium stearate are carried out successively mixing processes, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product; The weight ratio of described granule, Pulvis Talci, magnesium stearate is 100: 2.2: 0.24.

Embodiment 2: syrup prepared by the present invention

Get Flos Jasmini Sambac 240g, Radix Polygalae Wattersii 160g, Ramulus et Folium Bischofiae Javanicae 250g, Cauliset Folium Piperis Hancei 260g, Carnis Eretmochelydis 190g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 210g, Radix Plumbaginis Zeylanicae 290g, Semen Actinidiae Polygamae 160g, Herba Duchesneae Indicae 140g, Herba vallisneriae Spiralis 160g, Herba Strobilanthis Japonici 230g, Herba Verbenae 120g, Lignum Sappan 220g, Actinolitum 260g, Folium Ilicis Cornutae 90g, Herba goodyearae repentis 160g, Herba Xanthii 240g, Preparatum Glycyrrhizae 160g, Radix Schisandrae Bicoloris 230g, Air Bladder pseudosciaenae seu Acipenser 210g, Balanophora dioica R Br ex Royle 190g, Fructus Elaeagni Angustifoliae 260g, Semen setariae 250g, Herba Tricyrtis Pilosae 160g, Solenognathus 240g and Radix Habenariae Delavayi 170g.

The first step, Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) and Radix Plumbaginis Zeylanicae are mixed in described ratio, adding relative to the determining alcohol of 5 times, mixture is the ethanol of 85%, heating and refluxing extraction 3 times, each reflux, extract, 2 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 65 DEG C 60 DEG C, relative density is the medicinal liquid of 1.06, by dry with spray dryer for the concentrated solution after concentrated, be ground into 150 orders subsequently, obtain dry powder;

Second step, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae and Semen setariae being mixed in described ratio, be ground into powder, is that the ethanol of 90% is as solvent with determining alcohol, flood 60 hours, adopt percolation with the speed of 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25, dry with spray dryer, be ground into 150 orders subsequently, obtain dry powder, the quality of the ethanol added is 4 times of second step mixture quality;

3rd step, mixes surplus stock medical material in described ratio, add relative to mixture 5 times amount determining alcohol be 75% alcohol reflux 3 times, each 2 hours, filter, filtrate merges, and reclaims ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20, in 60 DEG C of reduced vacuum dryings, obtains dry powder;

4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 4 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 50%, potassium sorbate 0.25%.

Toxicity test:

Acute toxicity testing: application mice 60, male and female half and half, body weight 24 ~ 36g, carries out acute toxicity test.Mice is divided into two groups at random, i.e. matched group and administration group, before experiment, fasting 12 hours, is dissolved in water by Chinese medicinal tablet prepared by embodiments of the invention 1, (concentration is 8.46g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg (namely unit dosage form is 42.3 crude drugs/kg), and matched group gives normal saline, administration in one day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage tablet LD50>42.3 crude drug/kg of the present invention, every day, maximum dosage-feeding was 84.6 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention be 8.25g crude drug/day/people, adult body weight in 60KG, average dosage is 0.1375g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 30g) oral administration gavage Chinese medicine of the present invention is 615 times of quantity.Therefore Chinese medicine acute toxicity of the present invention is extremely low, clinical drug safety.

Long term toxicity test: Chinese medicine embodiment 1 tablet of the present invention to three groups of mices (often organize 20) by 13.21,25.43 and 42.67g crude drug/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Clinical data:

Case selection: 110 examples, at the medical patient with chloasma of undergraduate course, are women, age 26-45 year; The course of disease 4 months-11 years.110 routine patients are divided into 2 groups at random: treatment group 55 example, age 26-45 year; The course of disease 4 months-10 years 9 months.Matched group 55 example, age 28-45 year; The course of disease 6 months-11 years.The equal not statistically significants of aspect comparing difference (equal > 0.05) such as two groups of patient ages, sex, the state of an illness, clinical manifestations.

Diagnostic criteria: formulate " clinical diagnosis of chloasma and criterion of therapeutical effect " with reference to Dermatology Professional Committee of CAIM (Chinese Association Of Integrative Medicine) pigment disease group: face is filbert to dark brown, well-defined patch, usual symmetry distribution, NIP performance and squama; Without obvious subjective symptoms; Women is multiple, after mainly occurring in adolescence; The state of an illness can have seasonality, and the Chang Xiachong winter is light.

Exclusion standard: gestation or women breast-feeding their children; Be associated with liver, cardiovascular disease person; Malignant tumor patient; Once systematic treating mistake in 4 weeks; Treatments period stops treatment or changes medicine, method person; Curative effect or data not umbra sound Outcome measure person cannot be judged.

Therapeutic Method:

Treatment group: oral Chinese medicine embodiment 1 tablet of the present invention, every day 3 times, 30 days courses for the treatment of, treats 3 courses for the treatment of by each 3.

Matched group: oral vitamin C sheet 200mg/ time, vitamin E capsule 100mg/ time, each every day 3 times, 30 days courses for the treatment of, treats 3 courses for the treatment of.

Curative effect judging standard:

Methods of marking: skin lesion area integral, 0 is divided into without skin lesion, and 1 is divided into skin lesion area < 2cm ², 2 are divided into skin lesion area 2-4cm ², 3 are divided into skin lesion area > 4cm ²; Skin lesion color score, 0 is divided into normal skin tone, and 1 is divided into filbert, and 2 are divided into brown, and 3 are divided into dark brown; Total mark=skin lesion area scoring+skin lesion color score, total mark before the index that declines after treatment=(before treatment the rear total mark of total mark-treatment)/treatment.Observe the change of skin lesion area and shade before and after treatment: clinical cure: naked eyes to disappear > 90% depending on mottle area, and color disappears substantially, point system calculates index decreased >=0.8 after treatment.Effective: naked eyes to disappear > 60% depending on mottle area, and color is obviously thin out, point system calculates index decreased >=0.5 after treatment.Take a turn for the better: naked eyes to disappear > 30% depending on mottle area, and color is thin out, point system calculates index decreased >=0.3 after treatment.Invalid: naked eyes to disappear < 30% depending on mottle area, color change is not obvious, and point system calculates index decreased≤0 after treatment.

Therapeutic outcome: two groups treat 3 courses for the treatment of respectively after, statistical result is see table 1 and table 2.

Table 1 liang group treats Clinical efficacy comparison (unit: example) after 3 courses for the treatment of respectively

Group	n	Clinical cure	Effective	Take a turn for the better	Invalid	Total effective rate
							Treatment group	55	34	7	9	5	50(90.91％)
Matched group	55	17	12	12	14	41(74.55％)

As can be seen from Table 1, adopt treatment by Chinese herbs chloasma of the present invention, relative to matched group, on therapeutic effect, there is significant improvement.

After a table 2 liang group treats 3 courses for the treatment of respectively, healing number and time compare (unit: example)

Group	n	Medication 30 days	Medication 60 days	Medication 90 days
					Treatment group	34	11(20％)	26(47.27％)	34(61.82％)
Matched group	17	5(9.09％)	11(20％)	17(30.91％)

As can be seen from Table 2, adopt treatment by Chinese herbs chloasma of the present invention, relative to matched group, not only therapeutic effect is better, takes effect also faster.

According to the clinical statistics in toxicity test and above table, Chinese medicine provided by the invention have rapid-action, effective percentage is high, the advantage of determined curative effect, safe without toxic side effect.

Concrete case: grandson patient, female, 34 years old, patient's front two cheekbones after conceived March start appearance point lamellar chloasma, spread to surrounding gradually, likeness in form butterfly, a point puerperium chloasma does not disappear voluntarily, color is darker on the contrary, area presents spreading trend, comes to go to a doctor, patient's light purplish tongue, white and thin fur, deep pulse.Through using the tablet of the embodiment of the present invention 1, each 3, every day 3 times, after 10 days, chloasma is desalinated, and after 25 days, the area of chloasma obviously disappears, and after treating two courses for the treatment of, chloasma disappears, and color disappears substantially, clinical recovery, follows up a case by regular visits to 6 months without recurrence.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (8)

1. treat the Chinese medicine preparation of chloasma for one kind, it is characterized in that, described Chinese medicine preparation comprises following raw medicinal material: Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan, Actinolitum, Folium Ilicis Cornutae, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae, Semen setariae, Herba Tricyrtis Pilosae, Solenognathus and Radix Habenariae Delavayi.

2. Chinese medicine preparation as claimed in claim 1, it is characterized in that, the ratio of weight and number of described raw medicinal material is: Flos Jasmini Sambac 15 ~ 25 parts, Radix Polygalae Wattersii 10 ~ 20 parts, Ramulus et Folium Bischofiae Javanicae 15 ~ 30 parts, Cauliset Folium Piperis Hancei 20 ~ 30 parts, Carnis Eretmochelydis 10 ~ 25 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15 ~ 30 parts, Radix Plumbaginis Zeylanicae 20 ~ 30 parts, Semen Actinidiae Polygamae 15 ~ 25 parts, Herba Duchesneae Indicae 10 ~ 20 parts, Herba vallisneriae Spiralis 15 ~ 25 parts, Herba Strobilanthis Japonici 10 ~ 25 parts, Herba Verbenae 10 ~ 20 parts, Lignum Sappan 15 ~ 30 parts, Actinolitum 20 ~ 30 parts, Folium Ilicis Cornutae 5 ~ 15 parts, Herba goodyearae repentis 10 ~ 25 parts, Herba Xanthii 15 ~ 25 parts, Preparatum Glycyrrhizae 10 ~ 20 parts, Radix Schisandrae Bicoloris 15 ~ 30 parts, 10 ~ 25 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 10 ~ 20 parts, 20 ~ 30 parts, Fructus Elaeagni Angustifoliae, Semen setariae 15 ~ 25 parts, Herba Tricyrtis Pilosae 15 ~ 30 parts, Solenognathus 20 ~ 30 parts and Radix Habenariae Delavayi 15 ~ 25 parts.

3. Chinese medicine preparation as claimed in claim 1 or 2, it is characterized in that, the ratio of weight and number of described raw medicinal material is: Flos Jasmini Sambac 20 ~ 25 parts, Radix Polygalae Wattersii 15 ~ 20 parts, Ramulus et Folium Bischofiae Javanicae 20 ~ 25 parts, Cauliset Folium Piperis Hancei 25 ~ 30 parts, Carnis Eretmochelydis 15 ~ 20 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 20 ~ 25 parts, Radix Plumbaginis Zeylanicae 25 ~ 30 parts, Semen Actinidiae Polygamae 15 ~ 20 parts, Herba Duchesneae Indicae 10 ~ 15 parts, Herba vallisneriae Spiralis 15 ~ 20 parts, Herba Strobilanthis Japonici 20 ~ 25 parts, Herba Verbenae 10 ~ 15 parts, Lignum Sappan 20 ~ 25 parts, Actinolitum 25 ~ 30 parts, Folium Ilicis Cornutae 5 ~ 10 parts, Herba goodyearae repentis 15 ~ 20 parts, Herba Xanthii 20 ~ 25 parts, Preparatum Glycyrrhizae 15 ~ 20 parts, Radix Schisandrae Bicoloris 15 ~ 25 parts, 20 ~ 25 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 15 ~ 20 parts, 25 ~ 30 parts, Fructus Elaeagni Angustifoliae, Semen setariae 20 ~ 25 parts, Herba Tricyrtis Pilosae 15 ~ 20 parts, Solenognathus 20 ~ 25 parts and Radix Habenariae Delavayi 15 ~ 20 parts.

4. the Chinese medicine preparation as described in claims 1 to 3, it is characterized in that, the ratio of weight and number of described raw medicinal material is: Flos Jasmini Sambac 22 parts, Radix Polygalae Wattersii 19 parts, Ramulus et Folium Bischofiae Javanicae 21 parts, Cauliset Folium Piperis Hancei 28 parts, Carnis Eretmochelydis 16 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 24 parts, Radix Plumbaginis Zeylanicae 26 parts, Semen Actinidiae Polygamae 18 parts, Herba Duchesneae Indicae 12 parts, Herba vallisneriae Spiralis 19 parts, Herba Strobilanthis Japonici 21 parts, Herba Verbenae 15 parts, Lignum Sappan 21 parts, Actinolitum 29 parts, Folium Ilicis Cornutae 7 parts, Herba goodyearae repentis 18 parts, Herba Xanthii 21 parts, Preparatum Glycyrrhizae 19 parts, Radix Schisandrae Bicoloris 16 parts, 24 parts, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle 16 parts, 28 parts, Fructus Elaeagni Angustifoliae, Semen setariae 22 parts, Herba Tricyrtis Pilosae 19 parts, Solenognathus 21 parts and Radix Habenariae Delavayi 19 parts.

5. the Chinese medicine preparation as described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is tablet, and its preparation method comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan and Actinolitum mixing, add relative to mixture 3 times ~ 5 times amount determining alcohol be 55% ~ 65% alcohol reflux 2 times ~ 4 times, each 2 hours ~ 3 hours, filter, filtrate merges, and reclaims ethanol, being concentrated into 70 DEG C of relative densities is the mastic of 1.30 ~ 1.32, for subsequent use;

All the other raw medicinal materials are mixed in proportion by second step, add relative to mixture 3 ~ 5 times of water gagings, boil 2 ~ 4 hours, and filter, being concentrated into 70 DEG C of relative densities is the mastic of 1.27 ~ 1.29;

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C ~ 65 DEG C reduced vacuum dryings, get dry extract powder;

4th step, carries out mixing by described dried cream powder and starch and processes, obtain mastic mixture; Described mastic and the weight ratio of starch are 1: 0.01 ~ 0.02; Described mastic mixture is carried out pelletization treatment, dried, the mastic compound particles obtained;

5th step, described mastic compound particles and Pulvis Talci, magnesium stearate are carried out successively mixing processes, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product; The weight ratio of described granule, Pulvis Talci, magnesium stearate is 100: 1 ~ 3: 0.15 ~ 0.3.

6. the Chinese medicine preparation as described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is syrup, and its preparation method comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) and Radix Plumbaginis Zeylanicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,

Second step, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae and Semen setariae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;

3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;

4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.

7. a preparation method for the Chinese medicine preparation described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is tablet, and it comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Radix Plumbaginis Zeylanicae, Semen Actinidiae Polygamae, Herba Duchesneae Indicae, Herba vallisneriae Spiralis, Herba Strobilanthis Japonici, Herba Verbenae, Lignum Sappan and Actinolitum mixing, add relative to mixture 3 times ~ 5 times amount determining alcohol be 55% ~ 65% alcohol reflux 2 times ~ 4 times, each 2 hours ~ 3 hours, filter, filtrate merges, and reclaims ethanol, being concentrated into 70 DEG C of relative densities is the mastic of 1.30 ~ 1.32, for subsequent use;

All the other raw medicinal materials are mixed in proportion by second step, add relative to mixture 3 ~ 5 times of water gagings, boil 2 ~ 4 hours, and filter, being concentrated into 70 DEG C of relative densities is the mastic of 1.27 ~ 1.29;

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C ~ 65 DEG C reduced vacuum dryings, get dry extract powder;

4th step, carries out mixing by described dried cream powder and starch and processes, obtain mastic mixture; Described mastic and the weight ratio of starch are 1: 0.01 ~ 0.02; Described mastic mixture is carried out pelletization treatment, dried, the mastic compound particles obtained;

5th step, described mastic compound particles and Pulvis Talci, magnesium stearate are carried out successively mixing processes, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product; The weight ratio of described granule, Pulvis Talci, magnesium stearate is 100: 1 ~ 3: 0.15 ~ 0.3.

8. a preparation method for the Chinese medicine preparation described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is syrup, and its preparation method comprises the following steps:

The first step, by Flos Jasmini Sambac, Radix Polygalae Wattersii, Ramulus et Folium Bischofiae Javanicae, Cauliset Folium Piperis Hancei, Carnis Eretmochelydis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) and Radix Plumbaginis Zeylanicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,

Second step, Herba goodyearae repentis, Herba Xanthii, Preparatum Glycyrrhizae, Radix Schisandrae Bicoloris, Air Bladder pseudosciaenae seu Acipenser, Balanophora dioica R Br ex Royle, Fructus Elaeagni Angustifoliae and Semen setariae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;

3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;

4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.