CN105311534A - Anti-alcohol health instant soluble medicine and its preparation method - Google Patents
Anti-alcohol health instant soluble medicine and its preparation method Download PDFInfo
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- CN105311534A CN105311534A CN201410366958.2A CN201410366958A CN105311534A CN 105311534 A CN105311534 A CN 105311534A CN 201410366958 A CN201410366958 A CN 201410366958A CN 105311534 A CN105311534 A CN 105311534A
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Abstract
The invention discloses an anti-alcohol health instant soluble medicine and its preparation method. The anti-alcohol health instant soluble medicine is fully composed of medicinal and edible natural plants by weight: Semen Hoveniae 5 g, Radix Puerariae 8 g, Semen Lablab Album 8 g, Rhizoma Alpiniae Officinarum 3 g, Exocarpium Citri Leiocarpae 5 g, charred Fructus Crataegi 6 g, Fructus Tsaoko 3 g, Semen Coicis 15 g, Flos Chrysanthemi 15 g, and Herba Gynostemmatis Pentaphylli 15 g, all being edible and medicinal articles specified by China Ministry of Health; this formulation focuses on herbs resolving damp with aromatics; alcohol removal by diuresis is promoted through resolving damp and activating spleen with aromatics; herbal effective ingredients are extracted according to a specific process; the prepared instant soluble medicine is effective in both dispelling the effects of alcohol and keeping fitness and is free of toxic or side effect.
Description
Technical field
The invention belongs to biological medicine scientific research and innovation field, be under the jurisdiction of " biological and new medicine " new industry group, relate to technical field of health care food, be specifically related to a kind of hangover-alleviating health-care electuary and preparation method thereof.
Background technology
Investigation shows, due to the needs of social activity and the increase of social life pressure, excessive consumption of alcohol has become the public health problem of China.Ethanol has 95% to need to carry out oxidative metabolism by the enzyme system of liver after entering human body, it is acetaldehyde that ethanol enters human liver cell rear oxidation, and acetaldehyde has obvious toxicity to hepatocyte, makes its metabolism generation obstacle.Excessively for a long time to drink, will cause hepatocyte that steatosis, necrosis occur again and again, cause fibrosis and liver cirrhosis.Retrieve nearly 6 years Causes of Death Surveillance annual reports and find in hepatic disease in 2005, have 24% to be alcoholic liver cirrhosis; 40% is had to be alcoholic liver cirrhosis in hepatic disease in 2008; 46% is had to be alcoholic liver cirrhosis in hepatic disease in 2009; 41% is had to be alcoholic liver cirrhosis in hepatic disease in 2010.Drinking is too much the main cause causing alcoholic cirrhosis.Acute drinking except can cause nausea, vomit in a large number, hypomnesis, absent minded, fine movement capability deteriorates and emotional instability, contingency (as traffic accident) incidence rate more may be caused to increase, bring huge harm to the life of individual and society.
Spirits culture has long history in China, the pillar of various wine product local or national economy especially.Wine also plays extremely important social role in actual life, drinks unavoidably concerning somebody.So for a long time, people are finding safe and reliable disintoxicating product to remove always or are alleviating and drinking to the toxic and side effects of human body generation and the harm to life.And Western medicine relieves the effect of alcohol the main method (as naloxone) adopting diuresis and anti symptom treatment, this based article has certain curative effect for acute poisoning, and the organs and tissues pathological change caused for chronic poisoning then produces little effect.Chinese medicinal alcoholism-relieving is with a long history, and the chronic poisoning disease for the long-term excessive consumption of alcohol for the treatment of more has special effect.The alcohol-neutralize healthy product with Chinese herbal medicine being preparation is in the market in the ascendant, but most products or prescription are merely, and function is simple; Or prescription is complicated, security reliability is poor.Our Flos puerariae lobatae solution caudle is the etiology and pathogenesis for patient's insobriety easy damaged internal organs, on the basis of consulting a large amount of ancient literature, the experience medication of combined name old docter of TCM, from organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, more than 100 person-time on probation in clinical and the prescriptions of Chinese medicine with good antialcoholism action that finds.What the party formed that medicine all derives from health ministry regulation is food and the article of medicine, on probationly in life achieves good effect.
Summary of the invention
The object of the present invention is to provide and a kind of there is health instant powder of good antialcoholism action and preparation method thereof.
Technical scheme of the present invention is:
The weight proportion of hangover-alleviating health-care electuary raw material components is: Semen Hoveniae (Fructus Hoveniae) 5 grams, Radix Puerariae 8 grams, Semen Lablab Album 8 grams, Rhizoma Alpiniae Officinarum 3 grams, Pericarpium Citri tangerinae 5 grams, Fructus Crataegi (parched to brown) 6 grams, Fructus Tsaoko 3 grams, Semen Coicis 15 grams, Flos Chrysanthemi 15 grams, Herb Gynostemmae Pentaphylli 15 grams:
The preparation method of hangover-alleviating health-care electuary is carried out according to the following steps:
1) Radix Puerariae, Semen Lablab Album, Fructus Crataegi (parched to brown), Flos Chrysanthemi, Herb Gynostemmae Pentaphylli extract wherein water-soluble portion in aqueous alcohol mode;
Radix Puerariae, pulverizes, and 75% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Semen Lablab Album, pulverizes, and 95% ethanol 45 DEG C extracts 1 time, each 3h.Sucking filtration, Rotary Evaporators removes solvent;
Fructus Crataegi (parched to brown), pulverizes, and 75% ethanol 75 DEG C extracts twice, each 3h sucking filtration, and Rotary Evaporators removes solvent;
2) Rhizoma Alpiniae Officinarum, Pericarpium Citri tangerinae, Fructus Tsaoko obtain volatility position in supercritical fluid extraction mode.
Rhizoma Alpiniae Officinarum, pulverizes, and 95% ethanol 75 DEG C extracts once, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Pericarpium Citri tangerinae, pulverizes, and 80% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Fructus Tsaoko, pulverizes, and 95% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
3) Semen Hoveniae (Fructus Hoveniae), Semen Coicis water extract-alcohol precipitation mode obtain water soluble part
Semen Hoveniae (Fructus Hoveniae), pulverizes, and 80% ethanol 75 DEG C extracts 1 time, each 3h centrifugal 5000 turns 5 minutes, and Rotary Evaporators removes solvent;
Semen Coicis, pulverizes, and 95% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
4) by all for appeal extract mixing, add suitable adjuvant, make Flos puerariae lobatae alcohol-decomposing powder.
Beneficial effect of the present invention: adopt belong to health ministry regulation be food and the article of medicine, reuse removing dampness by means of aromatics class medicine simultaneously, to be amusing sharp alcoholism by removing dampness by means of aromatics, and extract medical material effective ingredient according to specific technique, the electuary prepared has the double effects that relieves the effect of alcohol and keep healthy, and has no side effect.
Detailed description of the invention:
Below in conjunction with embodiment, the invention will be further described:
Medical literature " property of medicine opinion " and supplement to the Herbal have for the drunk associated description how to dissolve, specific as follows:
Radix Puerariae " property of medicine opinion " is recorded " control sky capable on gas, vomiting, whetting the appetite, principal solution alcoholism, only excessive thirst.Endure bits and control incised wound, when controlling, disease is antipyretic." Semen Hoveniae (Fructus Hoveniae) can relieve the effect of alcohol preventing or arresting vomiting, relieving restlessness of quenching the thirst, dispelling wind and removing obstruction in the collateral, smoothening secretion.Supplement to the Herbal records it, and " relieving restlessness of quenching the thirst, go heat on diaphragm, moistening five ZANG-organs, sharp defecation, function is as honey." spleen invigorating of Semen Lablab Album energy, removing dampness, to relieve summer heat." Bencao Tujing " carries its " main woman's leukorrhagia.Doublely kill alcoholism, also separate tetrodotoxin, TTX." Rhizoma Alpiniae Officinarum has dispersing cold for relieving pain, the merit of warming middle-JIAO to arrest vomiting." Bencao Congxin " carries this product, and " warming the stomach cold expelling, help digestion relieving alcoholic intoxication, controls stomachache with cool feeling." Pericarpium Citri tangerinae energy and spleen, logical five types of stranguria." middle wine vomiting is felt sick, and decocts the effect of drink to record it in " daily book on Chinese herbal medicine "." Fructus Crataegi (parched to brown) energy spleen benefiting and stimulating the appetite, relieving dyspepsia; The merit of Fructus Tsaoko tool dampness cold expelling, expectorant preventing the attack (or recurrence) of malaria, because of gas fragrance, have and ward off turbid property, " book on Chinese herbal medicine " draws Li Gao cloud: " warming the spleen stomach, anti-nausea control that spleen-cold syndrome is wet, cold-phlegm ... disappear dyspepsia, and alcoholic intoxication, fruit amass, and doublely ward off miasma solution pestilence." Semen Coicis energy invigorating spleen and reinforcing stomach, diuretic dehumidifies; Flos Chrysanthemi energy dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight, heat-clearing and toxic substances removing." medicine mirror " carry its " ... separate drunkard's stupor, Yi Xing, altogether Radix puerariae decocts soup." Herb Gynostemmae Pentaphylli has good anti-stress effect, has blood sugar lowering, blood fat reducing and hepatoprotective effect.All medicines share energy invigorating spleen to remove dampness, and help digestion relieving alcoholic intoxication, alcoholic intoxication, only excessive thirst.
By furtheing investigate above-mentioned two medical literature and explore, sum up and summarize a kind of electuary with hangover-alleviating health-care effect, electuary prescription is as follows:
Semen Hoveniae (Fructus Hoveniae) 5 grams, Radix Puerariae 8 grams, Semen Lablab Album 8 grams, Rhizoma Alpiniae Officinarum 3 grams, Pericarpium Citri tangerinae 5 grams, Fructus Crataegi (parched to brown) 6 grams, Fructus Tsaoko 3 grams, Semen Coicis 15 grams, Flos Chrysanthemi 15 grams, Herb Gynostemmae Pentaphylli 15 grams:
And adopt specific production technology and preparation method for above-mentioned formula, its preparation method is as follows:
1) Radix Puerariae, Semen Lablab Album, Fructus Crataegi (parched to brown), Flos Chrysanthemi, Herb Gynostemmae Pentaphylli extract wherein water-soluble portion in aqueous alcohol mode;
Radix Puerariae, pulverizes, and 75% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Semen Lablab Album, pulverizes, and 95% ethanol 45 DEG C extracts 1 time, each 3h.Sucking filtration, Rotary Evaporators removes solvent;
Fructus Crataegi (parched to brown), pulverizes, and 75% ethanol 75 DEG C extracts twice, each 3h sucking filtration, and Rotary Evaporators removes solvent;
2) Rhizoma Alpiniae Officinarum, Pericarpium Citri tangerinae, Fructus Tsaoko obtain volatility position in supercritical fluid extraction mode.
Rhizoma Alpiniae Officinarum, pulverizes, and 95% ethanol 75 DEG C extracts once, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Pericarpium Citri tangerinae, pulverizes, and 80% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Fructus Tsaoko, pulverizes, and 95% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
3) Semen Hoveniae (Fructus Hoveniae), Semen Coicis water extract-alcohol precipitation mode obtain water soluble part
Semen Hoveniae (Fructus Hoveniae), pulverizes, and 80% ethanol 75 DEG C extracts 1 time, each 3h centrifugal 5000 turns 5 minutes, and Rotary Evaporators removes solvent;
Semen Coicis, pulverizes, and 95% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
4) by all for appeal extract mixing, add suitable adjuvant, make Flos puerariae lobatae alcohol-decomposing powder.
The electuary adopting above-mentioned preparation method to obtain possesses extraordinary to relieve the effect of alcohol and health-care effect, in order to prove the effect of above-mentioned electuary, in research and development and preparation process, we have done the test and detection of being correlated with, and comprise safety toxicology test, stability test, hygiene inspection, Physico-chemical tests and microorganism detection, both effectiveness test, effective component qualification test.
Claims (2)
1. a hangover-alleviating health-care electuary, it is characterized in that: what the effective ingredient of this electuary all belonged to health ministry regulation is food and the article of medicine, and the weight proportion of its raw material is: Semen Hoveniae (Fructus Hoveniae) 5 grams, Radix Puerariae 8 grams, Semen Lablab Album 8 grams, Rhizoma Alpiniae Officinarum 3 grams, Pericarpium Citri tangerinae 5 grams, Fructus Crataegi (parched to brown) 6 grams, Fructus Tsaoko 3 grams, Semen Coicis 15 grams, Flos Chrysanthemi 15, Herb Gynostemmae Pentaphylli 15 grams.
2. the preparation method of hangover-alleviating health-care electuary as claimed in claim 1, is characterized in that carrying out according to the following steps:
1) Radix Puerariae, Semen Lablab Album, Fructus Crataegi (parched to brown), Flos Chrysanthemi, Herb Gynostemmae Pentaphylli extract wherein water-soluble portion in aqueous alcohol mode;
Radix Puerariae, pulverizes, and 75% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Semen Lablab Album, pulverizes, and 95% ethanol 45 DEG C extracts 1 time, each 3h, sucking filtration, and Rotary Evaporators removes solvent;
Fructus Crataegi (parched to brown), pulverizes, and 75% ethanol 75 DEG C extracts twice, each 3h sucking filtration, and Rotary Evaporators removes solvent;
2) Rhizoma Alpiniae Officinarum, Pericarpium Citri tangerinae, Fructus Tsaoko obtain volatility position in supercritical fluid extraction mode;
Rhizoma Alpiniae Officinarum, pulverizes, and 95% ethanol 75 DEG C extracts once, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Pericarpium Citri tangerinae, pulverizes, and 80% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
Fructus Tsaoko, pulverizes, and 95% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
3) Semen Hoveniae (Fructus Hoveniae), Semen Coicis water extract-alcohol precipitation mode obtain water soluble part
Semen Hoveniae (Fructus Hoveniae), pulverizes, and 80% ethanol 75 DEG C extracts 1 time, each 3h centrifugal 5000 turns 5 minutes, and Rotary Evaporators removes solvent;
Semen Coicis, pulverizes, and 95% ethanol 75 DEG C extracts 1 time, each 3h sucking filtration, and Rotary Evaporators removes solvent;
4), by all for appeal extract mixing, add suitable adjuvant, make Flos puerariae lobatae alcohol-decomposing powder.
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Cited By (3)
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| CN105381306A (en) * | 2015-12-17 | 2016-03-09 | 湖南东蒙生物科技有限公司 | Teabag composition capable of relieving alcoholic liver, brain and heart injuries |
| CN107349359A (en) * | 2017-07-20 | 2017-11-17 | 南阳理工学院 | One kind being capable of Chinese medicinal composition for alleviating hangover |
| CN108378182A (en) * | 2018-02-11 | 2018-08-10 | 闽福林（厦门）医疗科技有限公司 | One kind is relieved the effect of alcohol chocolate |
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| CN105381306B (en) * | 2015-12-17 | 2019-03-08 | 湖南九味仙生物科技有限公司 | A kind of tea bag composition for alleviating alcoholic liver, brain and heart damage |
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| CN108378182A (en) * | 2018-02-11 | 2018-08-10 | 闽福林（厦门）医疗科技有限公司 | One kind is relieved the effect of alcohol chocolate |
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Application publication date: 20160210 |