CN105311518A - 一种治疗哮喘的药物及其制备方法 - Google Patents
一种治疗哮喘的药物及其制备方法 Download PDFInfo
- Publication number
- CN105311518A CN105311518A CN201510913492.8A CN201510913492A CN105311518A CN 105311518 A CN105311518 A CN 105311518A CN 201510913492 A CN201510913492 A CN 201510913492A CN 105311518 A CN105311518 A CN 105311518A
- Authority
- CN
- China
- Prior art keywords
- grams
- gram
- radix
- semen
- pick
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗哮喘的药物及其制备方法,其主要是由川贝母、柴胡、党参、茯苓、莱菔子、白果、射干、桑白皮、百部、蚯蚓、杏仁、葶苈子、远志、当归、乌梅、紫苏叶、灵芝草、厚朴、黄连、威灵仙、鱼腥草、杜仲、泽泻、淫羊藿、苍耳子、款冬花、吴茱萸按一定重量配比制备而成,本发明药物具有温润肺气,润肺散结,止嗽化痰,止咳平喘,滋补肝肾的功能,用于治疗哮喘见效快、疗效好,不复发。
Description
技术领域
本发明涉及一种治疗哮喘的药物及其制备方法,属中药领域。
背景技术
哮喘是由多种细胞和细胞组分参与的气道慢性炎症性疾病,这种慢性炎症与气道高反应性相关,通常出现广泛而多变的可逆性气流受限。中医则认为哮喘与内有痰饮,肺气升降不利,肺脾气虚,肺肾两亏有关。由于西药治疗副作用大,因此人们对有效治疗哮喘的中药药物存在极大的需求,至今为止,还没有发现关于本发明的有关报道。
发明内容
本发明人依据中医理论的研究和临床试验的反复验证,终于找到了有效治疗哮喘的药物,从而完成了本发明。
本发明的目的就是提供一种有效治疗哮喘的中药组合药物。
本发明的另一目的就是提供了该中药组合药物的制备方法。
本发明药物是选择川贝母、柴胡、党参、茯苓、莱菔子、白果、射干、桑白皮、百部、蚯蚓、杏仁、葶苈子、远志、当归、乌梅、紫苏叶、灵芝草、厚朴、黄连、威灵仙、鱼腥草、甘草、杜仲、泽泻、淫羊藿、苍耳子、白芷、款冬花、半夏、吴茱萸及小叶桑根进行组合制备的,将这些药物组合使得各药物功效产生协同作用,从而能够有效治疗哮喘。其中,选用川贝母是因为其性味苦甘,凉,入肺经,有润肺散结,止嗽化痰的功能,治虚劳咳嗽,吐痰咯血,心胸郁结,肺痿,肺痈,瘿瘤,瘰疬,喉痹,乳痈。选用柴胡是因为其性味苦,凉,入肝、胆经,有和解表里,疏肝,升阳的功能,治寒热往来,胸满胁痛,口苦耳聋,头痛目眩,疟疾,下利脱肛,***,子宫下垂。选用党参是因为其性味甘,平,入手、足太阴经气分,有补中益气,生津的功能,治脾胃虚弱,气血两亏,体倦无力,食少,口渴,久泻,脱肛。选用茯苓是因为其性味甘淡,平,入心、脾、肺经,有渗湿利水,益脾和胃,宁心安神的功能,治小便不利水肿胀痛,痰饮咳逆,呕哕,泄泻,遗精,淋浊,惊悸,健忘。选用莱菔子是因为其性味辛甘,平,入肺、胃经,有下气定喘,消食化痰的功能,治咳嗽痰喘,食积气滞,胸闷腹胀,下痢后重。选用白果是因为其性味甘苦涩,平,有毒,入肺、肾经,有敛肺气,定喘嗽,止带浊,缩小便的功能,治哮喘,痰嗽,白带,白浊,遗精,淋病,小便频数。选用射干是因为其性味苦,寒,有毒,入肺、肝经,有降火,解毒,散血,消痰的功能,治喉痹咽痛,咳逆上气,痰涎壅盛,瘰疬结核,疟母,妇女经闭,痈肿疮毒。选用桑白皮是因为其性味甘,寒,入肺、脾经,有泻肺平喘,行水消肿的功能,治肺热喘咳,吐血,水肿,脚气,小便不利。选用百部是因为其性味甘苦,微温,入肺经,有温润肺气,止咳,杀虫的功能,治风寒咳嗽,百日咳,肺结核,老年咳喘、蛔虫、蛲虫病,皮肤疥癣、湿疹。选用蚯蚓是因为其性味咸,寒,入肝、脾、肺经,有清热,平肝,止喘,通络的功能,治高热狂躁,惊风抽搐,风热头痛,目赤,中风半身不遂,喘息,喉痹,关节疼痛,齿衄,小便不通,瘰疬,痄腮,疮疡。选用杏仁是因为其性味苦,温,有毒,入肺、大肠经,有祛痰止咳,平喘,润肠的功能,治外感咳嗽,喘满,喉痹,肠燥便秘。选用葶苈子是因为其性味辛苦,寒,入肺、膀胱经,有下气行水的功能,治肺壅喘急,痰饮咳嗽,水肿胀满。选用远志是因为其性味苦辛,温,入心、肾经,有安神益智,祛痰,解郁的功能,治惊悸,健忘,梦遗,失眠,咳嗽多痰,痈疽疮肿。选用当归是因为其性味甘辛,温,入心、肝、脾经,有补血和血,调经止痛,润燥滑肠的功能,治***,经闭腹痛,癥瘕结聚,崩漏,血虚头痛,眩晕,痿痹,肠燥难便,赤痢后重,痈疽疮疡,金疮,跌扑损伤。选用乌梅是因为其性味酸,温,入肝,脾,肺,大肠经,有收敛生津,安蛔驱虫的功能,治久咳,虚热烦渴,久疟,痢疾,便血,尿血,血崩,蛔厥腹痛,呕吐,钩虫病,牛皮癣,胬肉。选用紫苏叶是因为其性味辛,温,入肺、脾经,有发表,散寒,理气,和营的功能,治感冒风寒,恶寒发热,咳嗽,气喘,胸腹胀满,胎动不安,并能解鱼蟹毒。选用灵芝草是因为其性味甘,平,有补气安神,止咳平喘的功能,治眩晕不眠,心悸气短,虚劳咳喘。选用厚朴是因为其性味苦辛,温,入脾、胃、大肠经,有温中,下气,燥湿,消痰的功能,治胸腹痞满胀痛,反胃、呕吐,宿食不消,痰饮喘咳,寒湿泻痢。选用黄连是因为其性味苦,寒,入心、肝、胃、大肠经,有泻火,燥湿,解毒,杀虫的功能,治时行热毒、伤寒,热盛心烦,痞满呕逆,菌痢,热泻腹痛,肺结核,吐、衄、下血,消渴,疳积,蛔虫病,百日咳,咽喉肿痛,火眼,口疮,痈疽疮毒,湿疹,汤火烫伤。选用威灵仙是因为其性味辛咸,温,有毒,入膀胱经,有祛风湿,通经络,消痰涎,散癖积的功能,治痛风、顽痹、腰膝冷痛,脚气,疟疾,癥瘕积聚,破伤风,扁桃体炎,诸骨鲠咽。选用鱼腥草是因为其性味辛,寒,入手太阴经,有清热解毒,利尿消肿的功能,治肺炎,肺脓疡,热痢,疟疾,水肿,淋病,白带,痈肿,痔疮,脱肛,湿疹,秃疮,疥癣。选用甘草是因为其性味甘平,入脾、胃、肺经,有和中缓急,润肺,解毒,调和诸药的功能,炙用治脾胃虚弱,食少,腹痛便溏,劳倦发热,肺痿咳嗽,心悸,惊痈,生用治咽喉肿痛,消化性溃疡,痈疽疮疡,解药毒及食物中毒。选用杜仲是因为其性味甘微辛,温,入肝、肾经,有补肝肾,强筋骨,安胎的功能,治腰脊酸疼,足膝痿弱,小便余沥,阴下湿痒,胎漏欲堕,高血压。选用泽泻是因为其性味甘,寒,入膀胱经,有利水,渗湿,泄热的功能,治小便不利,水肿肛满,呕吐,泻痢,痰饮,脚气,淋病,尿血。选用淫羊藿是因为其性味辛甘,温,入肝、肾经,有补肾壮阳,祛风除湿的功能,治阳痿不举,小便淋沥,筋骨挛急,半身不遂,腰膝无力,风湿痹痛,四脚不仁。选用苍耳子是因为其性味甘,温,有毒,入肺、肝经,有散风,止痛,祛湿,杀虫的功能,治风寒头痛,鼻渊,齿痛,风寒湿痹,四脚挛痛,疥癞,瘙痒。选用白芷是因为其性味辛,温,入肺、脾、胃经,有祛风,燥湿,消肿,止痛的功能,治头痛,眉棱骨痛,齿痛,鼻渊,寒湿腹痛,肠风痔漏,赤白带下,痈疽疮疡,皮肤燥痒,疥癣。选用款冬花是因为其性味辛,温,入肺经,有润肺下气,化痰止嗽的功能,治咳逆喘息,喉痹。选用半夏是因为其性味辛,温,有毒,入脾、胃经,有燥湿化痰,降逆止呕,清痞散结的功能,治湿痰冷饮呕吐,反胃,咳喘痰多,我膈胀满,痰厥头痛,头晕不眠,外消痈肿。选用吴茱萸是因为其性味辛苦,温,有毒,入肝、胃经,有温中,止痛,理气,燥湿的功能,治呕逆吞酸,厥阴头痛,脏寒吐泻,脘腹胀痛,脚气,疝气,口疮溃疡,齿痛,湿疹,黄水疮。小叶桑根性味辛甘、寒,有泻肺火,利小便的功能,治肺热咳嗽,衄血,水肿。
具体实施方式
本发明组分的药物用量也是发明人经过大量摸索总结得出的,各组分的用量在下述重量范围内都具有较好的疗效
川贝母15-25克,柴胡15-25克,党参20-30克,茯苓10-20克,莱菔子5-15克,白果3-7克,射干3-7克,桑白皮5-15克,百部7-12克,蚯蚓5-15克,杏仁3-7克,葶苈子5-15克,远志5-15克,当归10-20克,乌梅10-15克,紫苏叶5-15克,灵芝草3-9克,厚朴7-12克,黄连5-15克,威灵仙3-7克,鱼腥草10-20克,甘草10-20克,杜仲7-12克,泽泻5-15克,淫羊藿5-15克,苍耳子7-12克,白芷5-10克,款冬花10-20克,半夏5-15克,吴茱萸5-10克,小叶桑根15-25克。
优选为
川贝母20克,柴胡20克,党参25克,茯苓15克,莱菔子10克,白果5克,射干5克,桑白皮10克,百部9克,蚯蚓10克,杏仁5克,葶苈子10克,远志10克,当归15克,乌梅12克,紫苏叶10克,灵芝草6克,厚朴9克,黄连10克,威灵仙5克,鱼腥草15克,甘草15克,杜仲9克,泽泻10克,淫羊藿10克,苍耳子9克,白芷8克,款冬花15克,半夏10克,吴茱萸8克,小叶桑根20克。
本发明药物的制备方法如下
一、备料
1、川贝母:拣去杂质,用水浸泡,捞出,闷润,剥去心,晒干;
2、柴胡:拣去杂质,除去残茎,洗净泥沙,捞出,润透后及时切片,晒干;
3、党参:洗净泥沙后润透去芦,切片或切段,晒干;
4、茯苓:用水浸泡,洗净捞出,闷透后,切片,晒干;
5、莱菔子:簸去杂质,漂净泥土,捞出,晒干,用时捣碎;
6、白果:拣净杂质,除去硬壳;
7、射干:拣去杂质,水洗净,稍浸泡,捞出,润透,切片,晒干,筛去须、屑;
8、桑白皮:刷去灰屑,洗净,润透后切丝,晒干;
9、百部:拣净杂质,除去须根,洗净,润透后切段,晒干;
10、蚯蚓:拣去杂质,用水漂净,及时捞出,晒干,切段;
11、杏仁:拣净杂质,置沸水中略煮,俟皮微皱起捞出,浸凉水中,脱去种皮,晒干,簸净;
12、葶苈子:拣净杂质,筛去灰屑;
13、远志:拣去杂质,切段,筛去灰屑;
14、当归:拣去杂质,洗净,闷润,稍晾,切片晒干;
15、乌梅:拣净杂质,筛去灰屑,洗净,晒干;
16、紫苏叶:拣去杂质,晒干;
17、灵芝草:除去杂质,洗净,润软,切厚片,干燥,筛去碎屑;
18、厚朴:用水浸泡捞出,润透后刮去粗皮,洗净,切丝,晾干;
19、黄连:拣去杂质,洗净泥砂,润透,切片,阴干;
20、威灵仙:拣净杂质,除去残茎,用水浸泡,捞出润透,切段,晒干;
21、鱼腥草:去净杂质,除去残根,洗净切段,晒干;
22、甘草:拣去杂质,洗净,用水浸泡至八成透时,捞出,润透切片,晾干;
23、杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干;
24、泽泻:拣去杂质,大小分档,用水浸泡至八成透,捞出,晒凉,闷润至内外湿度均匀,切片,晒干;
25、淫羊藿:拣净杂质,去梗,切丝,筛去碎屑;
26、苍耳子:拣尽杂质,去刺,筛去灰屑,微炒至黄色,取出放凉;
27、白芷:拣净杂质,用水洗净,浸泡,捞出润透,略晒至外皮无滑腻感时,再闷润后,切片干燥;
28、款冬花:取拣净的款冬花同炼蜜加适量开水,拌匀,稍闷,放锅内用文火炒至深黄色,不粘手为止,取出放凉,每款冬花10斤用炼蜜25斤;
29、半夏:拣去杂质,筛去灰屑;
30、吴茱萸:取原药材,除去果柄、枝及杂质,筛去碎屑;
31小叶桑根:拣净杂质,洗净润透,切段,晒干;
二、制备
1、将炮制后的川贝母、柴胡、党参、茯苓、莱菔子、白果、射干、桑白皮、百部、蚯蚓、杏仁、葶苈子、远志、当归、乌梅、紫苏叶、灵芝草、厚朴、黄连、威灵仙、鱼腥草、甘草、杜仲、泽泻、淫羊藿、苍耳子、白芷、款冬花、半夏、吴茱萸、小叶桑根放入煎药容器内,第一次加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
2、将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
3、将两次煎煮液混合搅拌均匀,分为4剂服用。
组方中川贝母有润肺散结,止嗽化痰,治虚劳咳嗽,吐痰咯血,心胸郁结,肺痿的功能为君药;杜仲补肝,益肾;百部有温润肺气,止咳,治风寒咳嗽,百日咳,肺结核,老年咳喘的功能,二者为臣药,三味药共同发挥温润肺气,润肺散结,止嗽化痰,补肝,益肾的作用,治疗哮喘效力全面,且以温润肺气,润肺散结,止嗽化痰为主可治本,甘草有和中缓急,润肺,解毒,调和诸药,解药毒及食物中毒的功能为佐药,灵芝草有止咳平喘,治虚劳咳喘的功能为使药,与余下诸药是治标。
本发明药物具有温润肺气,润肺散结,止嗽化痰,止咳平喘,滋补肝肾的功能,用于治疗哮喘,疗程短、见效快、治愈后不复发。
具体实施方式
以下通过试验例来进一步阐述本发明所述药物的有益效果,这些试验例包括本发明药物的动物毒性试验报告和临床疗效观察资料。
[试验例1]本发明药物的动物毒性试验报告:
取家兔30只,雌雄兼用,体重2.0—2.5kg,分两组,每组15只,其中一组为超剂量试验组,另一组为正常量试验组。超常量组为20ml/kg,正常量为10ml/kg,给药方式为灌胃法给药,每天两次,连服7天,每天观察给药反应,结果表明二组家兔活动、饮食正常,药物无不良毒副作用。
[试验例2]本发明药物的临床疗效观察
1、一般资料
收治哮喘门诊患者共30例。
2、诊断标准
典型症状为反复发作的喘息、气促、胸闷或咳嗽等症状,多在夜间或清晨发作、加剧,多数患者可自行缓解或经治疗缓解,严重者被迫采取坐位或呈端坐呼吸,干咳或咳大量白色泡沫痰,甚至出现发绀等等症状。
3、治疗方法
选用上述药剂,给患者服用,每次服用1剂,每天早、晚各服1次,10天为一个疗程,连续服用3个疗程。
4、疗效评定标准
显效:哮喘症状消失,体质恢复正常,痊愈;
好转:患者喘息,呼吸急促,胸闷,咳嗽的症状减轻,哮喘症状明显好转,体质逐步恢复;
无效:达不到好转标准者。
5、治疗结果(见下表)
在上述治疗中,用本发明药物治疗哮喘患者30例,结果显效22例,显效率为73.33%,好转6例,好转率为20%,无效2例,总有效率为93.33%。
Claims (3)
1.一种治疗哮喘的药物,其特征在于:它是由下列重量范围内的原料药制成:
川贝母15-25克,柴胡15-25克,党参20-30克,茯苓10-20克,莱菔子5-15克,白果3-7克,射干3-7克,桑白皮5-15克,百部7-12克,蚯蚓5-15克,杏仁3-7克,葶苈子5-15克,远志5-15克,当归10-20克,乌梅10-15克,紫苏叶5-15克,灵芝草3-9克,厚朴7-12克,黄连5-15克,威灵仙3-7克,鱼腥草10-20克,甘草10-20克,杜仲7-12克,泽泻5-15克,淫羊藿5-15克,苍耳子7-12克,白芷5-10克,款冬花10-20克,半夏5-15克,吴茱萸5-10克,小叶桑根15-25克。
2.根据权利要求1所述的药物,其中各原料药的用量为:
川贝母20克,柴胡20克,党参25克,茯苓15克,莱菔子10克,白果5克,射干5克,桑白皮10克,百部9克,蚯蚓10克,杏仁5克,葶苈子10克,远志10克,当归15克,乌梅12克,紫苏叶10克,灵芝草6克,厚朴9克,黄连10克,威灵仙5克,鱼腥草15克,甘草15克,杜仲9克,泽泻10克,淫羊藿10克,苍耳子9克,白芷8克,款冬花15克,半夏10克,吴茱萸8克,小叶桑根20克。
3.根据权利要求1或2所述药物的制备方法,它包括下列步骤:
(一)备料
(1)川贝母:拣去杂质,用水浸泡,捞出,闷润,剥去心,晒干;
(2)柴胡:拣去杂质,除去残茎,洗净泥沙,捞出,润透后及时切片,晒干;
(3)党参:洗净泥沙后润透去芦,切片或切段,晒干;
(4)茯苓:用水浸泡,洗净捞出,闷透后,切片,晒干;
(5)莱菔子:簸去杂质,漂净泥土,捞出,晒干,用时捣碎;
(6)白果:拣净杂质,除去硬壳;
(7)射干:拣去杂质,水洗净,稍浸泡,捞出,润透,切片,晒干,筛去须、屑;
(8)桑白皮:刷去灰屑,洗净,润透后切丝,晒干;
(9)百部:拣净杂质,除去须根,洗净,润透后切段,晒干;
(10)蚯蚓:拣去杂质,用水漂净,及时捞出,晒干,切段;
(11)杏仁:拣净杂质,置沸水中略煮,俟皮微皱起捞出,浸凉水中,脱去种皮,晒干,簸净;
(12)葶苈子:拣净杂质,筛去灰屑;
(13)远志:拣去杂质,切段,筛去灰屑;
(14)当归:拣去杂质,洗净,闷润,稍晾,切片晒干;
(15)乌梅:拣净杂质,筛去灰屑,洗净,晒干;
(16)紫苏叶:拣去杂质,晒干;
(17)灵芝草:除去杂质,洗净,润软,切厚片,干燥,筛去碎屑;
(18)厚朴:用水浸泡捞出,润透后刮去粗皮,洗净,切丝,晾干;
(19)黄连:拣去杂质,洗净泥砂,润透,切片,阴干;
(20)威灵仙:拣净杂质,除去残茎,用水浸泡,捞出润透,切段,晒干;
(21)鱼腥草:去净杂质,除去残根,洗净切段,晒干;
(22)甘草:拣去杂质,洗净,用水浸泡至八成透时,捞出,润透切片,晾干;
(23)杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干;
(24)泽泻:拣去杂质,大小分档,用水浸泡至八成透,捞出,晒凉,闷润至内外湿度均匀,切片,晒干;
(25)淫羊藿:拣净杂质,去梗,切丝,筛去碎屑;
(26)苍耳子:拣尽杂质,去刺,筛去灰屑,微炒至黄色,取出放凉;
(27)白芷:拣净杂质,用水洗净,浸泡,捞出润透,略晒至外皮无滑腻感时,再闷润后,切片干燥;
(28)款冬花:取拣净的款冬花同炼蜜加适量开水,拌匀,稍闷,放锅内用文火炒至深黄色,不粘手为止,取出放凉,每款冬花10斤用炼蜜25斤;
(29)半夏:拣去杂质,筛去灰屑;
(30)吴茱萸:取原药材,除去果柄、枝及杂质,筛去碎屑;
(31)小叶桑根:拣净杂质,洗净润透,切段,晒干;
(二)制备
(1)将炮制后的川贝母、柴胡、党参、茯苓、莱菔子、白果、射干、桑白皮、百部、蚯蚓、杏仁、葶苈子、远志、当归、乌梅、紫苏叶、灵芝草、厚朴、黄连、威灵仙、鱼腥草、甘草、杜仲、泽泻、淫羊藿、苍耳子、白芷、款冬花、半夏、吴茱萸、小叶桑根放入煎药容器内,加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
(2)将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
(3)将两次煎煮液混合搅拌均匀,分为4剂服用。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510913492.8A CN105311518A (zh) | 2015-12-12 | 2015-12-12 | 一种治疗哮喘的药物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510913492.8A CN105311518A (zh) | 2015-12-12 | 2015-12-12 | 一种治疗哮喘的药物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105311518A true CN105311518A (zh) | 2016-02-10 |
Family
ID=55240474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510913492.8A Pending CN105311518A (zh) | 2015-12-12 | 2015-12-12 | 一种治疗哮喘的药物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105311518A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107080829A (zh) * | 2017-04-28 | 2017-08-22 | 徐士魁 | 一种治疗哮喘的药物及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1465380A (zh) * | 2002-07-19 | 2004-01-07 | 王星杰 | 治疗哮喘的中药组合物及其制备方法 |
CN102772640A (zh) * | 2012-08-20 | 2012-11-14 | 孙凤梅 | 一种治疗哮喘的药物及其制备方法 |
-
2015
- 2015-12-12 CN CN201510913492.8A patent/CN105311518A/zh active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1465380A (zh) * | 2002-07-19 | 2004-01-07 | 王星杰 | 治疗哮喘的中药组合物及其制备方法 |
CN102772640A (zh) * | 2012-08-20 | 2012-11-14 | 孙凤梅 | 一种治疗哮喘的药物及其制备方法 |
Non-Patent Citations (1)
Title |
---|
利永聪: ""定喘汤加减治疗支气管哮喘66例"", 《基层医学论坛》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107080829A (zh) * | 2017-04-28 | 2017-08-22 | 徐士魁 | 一种治疗哮喘的药物及其制备方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105327296A (zh) | 一种治疗消化性溃疡的药物及其制备方法 | |
CN105477614A (zh) | 一种治疗肥胖的药物及其制备方法 | |
CN105477487A (zh) | 一种治疗慢性咽炎的药物及其制备方法 | |
CN105362822A (zh) | 一种治疗痤疮的药物及其制备方法 | |
CN105148106A (zh) | 一种治疗肺痨的药物及其制备方法 | |
CN103735934B (zh) | 一种治疗腰部疼痛的药物及其制备方法 | |
CN105381411A (zh) | 一种治疗癫痫的药物及其制备方法 | |
CN105362889A (zh) | 一种治疗耳鸣的药物及其制备方法 | |
CN105343490A (zh) | 一种治疗痔疮的药物及其制备方法 | |
CN104398925A (zh) | 一种治疗皮肤病的药物及其制备方法 | |
CN106421672A (zh) | 一种治疗流行性腮腺炎的药物及其制备方法 | |
CN106075247A (zh) | 一种治疗慢性尿潴留的药物及其制备方法 | |
CN105412665A (zh) | 一种治疗麻疹的药物及其制备方法 | |
CN105311518A (zh) | 一种治疗哮喘的药物及其制备方法 | |
CN103751752B (zh) | 一种治疗痢疾的药物及其制备方法 | |
CN106177857A (zh) | 一种治疗习惯性流产的药物及其制备方法 | |
CN105456856A (zh) | 一种治疗慢性咳嗽的药物及其制备方法 | |
CN105343582A (zh) | 一种治疗破伤风的药物及其制备方法 | |
CN105381416A (zh) | 一种治疗上消化道出血的药物及其制备方法 | |
CN105963586A (zh) | 一种治疗肺脓肿的药物及其制备方法 | |
CN105343854A (zh) | 一种治疗胃脘痛的药物及其制备方法 | |
CN105327327A (zh) | 一种治疗急性胆囊炎的药物及其制备方法 | |
CN105943894A (zh) | 一种治疗急性卡他性结膜炎的药物及其制备方法 | |
CN105412825A (zh) | 一种治疗高脂血症的药物及其制备方法 | |
CN105435034A (zh) | 一种治疗咯血的药物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160210 |
|
RJ01 | Rejection of invention patent application after publication |