CN105295553B - A kind of hydrogen peroxide plasma sterilizing color shifting ink and preparation method thereof - Google Patents
A kind of hydrogen peroxide plasma sterilizing color shifting ink and preparation method thereof Download PDFInfo
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- CN105295553B CN105295553B CN201510742657.XA CN201510742657A CN105295553B CN 105295553 B CN105295553 B CN 105295553B CN 201510742657 A CN201510742657 A CN 201510742657A CN 105295553 B CN105295553 B CN 105295553B
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Abstract
The present invention relates to a kind of hydrogen peroxide plasma sterilizing color shifting ink and preparation method thereof, belong to medical supplies sterilizing detection technique field；By color shifting ink and common pigments two parts, wherein camouflage paint is made up of 0.8 ~ 1.2g of methyl blue, 6 ~ 10g of crystal violet, 6500 ~ 7500ml of absolute alcohol, 800 ~ 1200ml of ethyl acetate, 45 ~ 55ml of triethanolamine, 800 ~ 1200ml of butyl acetate, 2.8 ~ 3.2kg of PU resin glues；Common pigments are made up of 0.1 ~ 0.3g of phenosafraine, 45 ~ 55ml of absolute alcohol；Its preparation method is to add methyl blue, crystal violet in absolute alcohol, after stirring and dissolving, adds ethyl acetate, butyl acetate, triethanolamine, after then the solution dissolved is filtered, and adds PU resin glues and camouflage paint is made；Phenosafraine is added into absolute alcohol stirring and dissolving common pigments are made, finally the common pigments of preparation are added in camouflage paint, stirs and produces；Color shifting ink sensitivity prepared by the inventive method is high, and stability is strong, and discoloration is thorough, can quick detection sterilization effect and, the time used is short, and accuracy rate is high.
Description
Technical field
The present invention relates to a kind of color shifting ink and preparation method thereof, and in particular to a kind of hydrogen peroxide plasma sterilizing discoloration
Ink and preparation method thereof, belongs to medical supplies detection technique field.
Background technology
With the fast development of China's economic, people's living standard improves and the level of understanding of health is improved constantly, right
The demand of various Medical Devices and articles for use is more and more, and these equipment and supplies are using preceding needing to carry out at strict sterilizing
Reason, conventional sterilization method is high-temperature sterilization.With the continuous improvement developed rapidly with medical technology of medical and health care system, respectively
Sensitive instrument and equipment is planted by progressively popularization and application, and these equipment can not typically carry out high-temperature sterilization.
In order to solve this problem, various low temperature sterilization methods are arisen at the historic moment, and most common of which is following three kinds：（1）
Oxirane low temperature sterilization；（2）Low-temperature formaldehyde vapor sterilizes；（3）Hydrogen peroxide plasma sterilizes.After comparing, peroxide
Change hydrogen plasma sterilization method to have the following advantages compared with the above two：1. sterilizing speed is fast, if 55min, and when need not detoxify
Between；2. the microorganism of kill and residue can be taken away by gas-circulating system, non-residual toxicity material；3. it is finally decomposed to
Water and oxygen, to environment and medical worker's non-hazardous；4. it is easy to install, it is not necessary to special room, it is not necessary to divulge information, arrange
The optional equipments such as water.Caused by the bactericidal action of hydrogen peroxide plasma is composite factor, mainly including temperature, ultraviolet light, height
Can particle and living radical etc..Wherein it is topmost be probably living radical effect, i.e. peroxidating in plasma
Hydrogen-based, hydroxyl isoreactivity material, are easily combined with the protein and nucleic acid in bacterial body, are destroyed its metabolism, are disappeared so as to play
Malicious sterilization functions.
The health industry standard that People's Republic of China's national healths in 2009 and Family Planning Committee promulgate《Hospital disappears
Malicious supply center's Part III：Cleaning and sterilizing and sterilizing effect monitoring standard》（ws310.3-2009）It is required that sterilization process needs
The monitoring chemical indicator in bag, after use, can be used to seal up for safekeeping as sterilizing record.Current medical disinfecting sterilizing indicator tape is
One journey sterilization process indicates product, and by the instruction ink on adhesive tape, color changes after sterilized sterilization functions, so that
Judge that article, whether by disinfecting, intuitively easily reacts article sterilizing state.Such as Chinese patent
CN201310517165.1 discloses a kind of screen print epoxy ethane sterilizing color shifting ink and preparation method thereof, can effectively improve
Sterilization effect is monitored, shortens sterilization time, and production cost is low, reasonable raw material proportioning.Chinese patent CN201182775Y is disclosed
A kind of color-changing printing ink indicating card for indicating disinfection, is applied by white PVC paper cards, color shifting ink coating and the color lump of contrast
Layer is constituted, for the detection of disinfecting process in sterilizing machine of low-temperature plasma, but the not formula to color shifting ink and preparation
Method is disclosed.
The content of the invention
It is contemplated that overcoming the deficiencies in the prior art, there is provided a kind of hydrogen peroxide plasma sterilizing color shifting ink and its system
Preparation Method, make preparation color shifting ink have stability it is good, discoloration thoroughly, full color, efficiency high, be adapted to a variety of printing equipments
The characteristics of.
In order to solve the above problems, the technical solution adopted in the present invention is：
A kind of hydrogen peroxide plasma sterilizing color shifting ink, including color shifting ink and common pigments two parts, color shifting ink
That by hyacinthine bleach after hydrogen peroxide oxidation, common pigments remain for the red pigment that can not be oxidized, specifically by
Following components is constituted：
Camouflage paint：0.8 ~ 1.2g of methyl blue, 6 ~ 10g of crystal violet, 6500 ~ 7500ml of absolute alcohol, ethyl acetate 800 ~
1200ml, 45 ~ 55ml of triethanolamine, 800 ~ 1200ml of butyl acetate, 2.8 ~ 3.2kg of PU resin glues；
Common pigments：0.1 ~ 0.3g of phenosafraine, 45 ~ 55ml of absolute alcohol.
A kind of preparation method of hydrogen peroxide plasma sterilizing color shifting ink, comprises the following steps：
（1）The preparation of camouflage paint：Methyl blue, crystal violet are added in absolute alcohol, 20 ~ 30min of stirring at low speed is whole
After dissolving, ethyl acetate, butyl acetate, triethanolamine 1 ~ 2min of stirring at low speed again are added, then the solution dissolved is filtered
Afterwards, PU resin glues, then stirring at low speed 10 minutes are added；
（2）The preparation of common pigments：Phenosafraine is added into absolute alcohol 5 ~ 8min of stirring at low speed, it is dissolved；
（3）Ink is synthesized：The common pigments of preparation are added in camouflage paint, 10 ~ 12min of stirring at low speed, allow common face
Material is all dissolved among camouflage paint, that is, is made into a kind of hydrogen peroxide plasma sterilizing color shifting ink.
Described stirring at low speed refers to 30~60r/min.
Step（1）Described filtering referred to 200~300 mesh filter screens.
The beneficial effects of the invention are as follows：
（1）Compound using Multiple components, intermolecular interaction enables pigment to penetrate article, quick detection sterilizing effect
Discoloration is really realized, the time used is short, accuracy rate is high.
（2）Color shifting ink sensitivity prepared by the present invention is high, and adhesive force is strong, full color, and discoloration is thorough, and stability
It is good.
（3）The inventive method simple possible, it is with low cost, it is adapted to large-scale promotion.
Embodiment
The present invention is described in further details below by example, these examples are only used for illustrating the present invention, do not limit
The scope of the present invention processed.
Embodiment 1
A kind of hydrogen peroxide plasma sterilizing color shifting ink, including color shifting ink and common pigments two parts, by with the following group
It is grouped into：
Camouflage paint：Methyl blue 0.8g, crystal violet 6g, absolute alcohol 6500ml, ethyl acetate 800ml, triethanolamine
45ml, butyl acetate 800ml, PU resin glue 2.8kg；
Common pigments：Phenosafraine 0.1g, absolute alcohol 45ml.
A kind of preparation method of hydrogen peroxide plasma sterilizing color shifting ink, comprises the following steps：
（1）The preparation of camouflage paint：Methyl blue, crystal violet are added in absolute alcohol, it is complete with 120r/min stirrings 20min
After portion's dissolving, add ethyl acetate, butyl acetate, triethanolamine and stir 1min under the conditions of 120r/min again, then will dissolving
Good solution is crossed after 300 mesh sieves, adds PU resin glues, is stirred 10 minutes with 120r/min speed；
（2）The preparation of common pigments：Phenosafraine is added into absolute alcohol, 5min is stirred with 120r/min, it is dissolved；
（3）Ink is synthesized：The common pigments of preparation are added in camouflage paint, 10min is stirred with 120r/min, allow common
Pigment is all dissolved among camouflage paint, that is, is made into a kind of hydrogen peroxide plasma sterilizing color shifting ink.
Embodiment 2
A kind of hydrogen peroxide plasma sterilizing color shifting ink, including color shifting ink and common pigments two parts, by with the following group
It is grouped into：
Camouflage paint：Methyl blue 1.2g, crystal violet 10g, absolute alcohol 7500ml, ethyl acetate 1200ml, triethanolamine
55ml, butyl acetate 1200ml, PU resin glue 3.2kg；
Common pigments：Phenosafraine 0.3g, absolute alcohol 55ml.
A kind of preparation method of hydrogen peroxide plasma sterilizing color shifting ink, comprises the following steps：
（1）The preparation of camouflage paint：Methyl blue, crystal violet are added in absolute alcohol, it is whole to mix 30min with 100r/min
After dissolving, add ethyl acetate, butyl acetate, triethanolamine and 2min is stirred with 100r/min again, then by the solution dissolved
2000 mesh sieves are crossed, PU resin glues are added, are stirred 10 minutes with 100r/min；
（2）The preparation of common pigments：Phenosafraine is added into absolute alcohol, 8min is stirred with 100r/min, it is dissolved；
（3）Ink is synthesized：The common pigments of preparation are added in camouflage paint, 12min is stirred with 100r/min, allow common
Pigment is all dissolved among camouflage paint, that is, is made into a kind of hydrogen peroxide plasma sterilizing color shifting ink.
Embodiment 3
A kind of hydrogen peroxide plasma sterilizing color shifting ink, including color shifting ink and common pigments two parts, by with the following group
It is grouped into：
Camouflage paint：Methyl blue 1g, crystal violet 8g, absolute alcohol 7000ml, ethyl acetate 1000ml, triethanolamine
50ml, butyl acetate 1000ml, PU resin glue 3kg；
Common pigments：Phenosafraine 0.2g, absolute alcohol 50ml.
A kind of preparation method of hydrogen peroxide plasma sterilizing color shifting ink, comprises the following steps：
（1）The preparation of camouflage paint：Methyl blue, crystal violet are added in absolute alcohol, 25min is mixed with 80r/min speed
All after dissolving, add ethyl acetate, butyl acetate, triethanolamine and 1.5min is stirred with 80r/min again, then will dissolve
Solution crosses 2200 mesh sieves, adds PU resin glues, then stir 10 minutes with 80r/min；
（2）The preparation of common pigments：Phenosafraine is added into absolute alcohol, 6min is stirred with 80r/min, it is dissolved；
（3）Ink is synthesized：The common pigments of preparation are added in camouflage paint, 11min is stirred with 80r/min, allow common
Pigment is all dissolved among camouflage paint, that is, is made into a kind of hydrogen peroxide plasma sterilizing color shifting ink.
Embodiment 4
The hydrogen peroxide plasma sterilizing color shifting ink performance measurement of embodiment：
Basic materialization performance test, according to CSSD testing standard to the sterilization time of embodiment product, color changeable effect, attached
Put forth effort, the performance such as stability is tested, as a result as shown in table 1：
The performance measurement result of the hydrogen peroxide plasma of table 1 sterilizing color shifting ink
Therefore, the hydrogen peroxide plasma sterilizing color shifting ink prepared using the inventive method complies fully with national standard will
Ask.
Claims (2)
- The color shifting ink 1. a kind of hydrogen peroxide plasma sterilizes, it is characterised in that：Including color shifting ink and common pigments two parts, It is composed of the following components：Camouflage paint：0.8 ~ 1.2g of methyl blue, 6 ~ 10g of crystal violet, 6500 ~ 7500mL of absolute alcohol, ethyl acetate 800 ~ 1200mL, 45 ~ 55mL of triethanolamine, 800 ~ 1200mL of butyl acetate, 2.8 ~ 3.2kg of PU resin glues；Common pigments：0.1 ~ 0.3g of phenosafraine, 45 ~ 55mL of absolute alcohol.
- A kind of method of color shifting ink 2. hydrogen peroxide plasma for being used to prepare described in claim 1 sterilizes, it is characterised in that： Comprise the following steps：（1）The preparation of camouflage paint：Methyl blue, crystal violet are added in absolute alcohol, 20 ~ 30min of stirring at low speed all dissolves Afterwards, ethyl acetate, butyl acetate, triethanolamine 1 ~ 2min of stirring at low speed again are added, after then the solution dissolved is filtered, plus Enter PU resin glues, then stirring at low speed 10 minutes；（2）The preparation of common pigments：Phenosafraine is added into absolute alcohol 5 ~ 8min of stirring at low speed, it is dissolved；（3）Ink is synthesized：The common pigments of preparation are added in camouflage paint, 10 ~ 12min of stirring at low speed makes common pigments complete Portion is dissolved among camouflage paint, that is, is made into a kind of hydrogen peroxide plasma sterilizing color shifting ink；Described stirring at low speed refers to 60~120r/min；Step（1）Described filtering referred to 200~300 mesh filter screens.
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| CN110538339A (en) * | 2019-09-11 | 2019-12-06 | 衡水诺盾生物科技有限公司 | hydrogen peroxide plasma five-class card sterilization challenge device and manufacturing method thereof |
| CN110938329A (en) * | 2019-12-23 | 2020-03-31 | 深圳市安达医疗感控科技有限公司 | Hydrogen peroxide low-temperature plasma sterilization indicating ink |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1610561A (en) * | 2001-12-31 | 2005-04-27 | 3M创新有限公司 | Hydrogen peroxide and peracetic acid indicators and methods using the same |
| CN201727766U (en) * | 2010-05-11 | 2011-02-02 | 冠晶光电股份有限公司 | Sterilizing device with detecting function |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP5461019B2 (en) * | 2009-01-15 | 2014-04-02 | 東京インキ株式会社 | Autoclave indicator ink, coated product having autoclave indicator ink layer, autoclave indicator sheet and sterilization bag |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1610561A (en) * | 2001-12-31 | 2005-04-27 | 3M创新有限公司 | Hydrogen peroxide and peracetic acid indicators and methods using the same |
| CN201727766U (en) * | 2010-05-11 | 2011-02-02 | 冠晶光电股份有限公司 | Sterilizing device with detecting function |
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Effective date of registration: 20230421 Address after: No. 3 Zhihui Road, Guangzhou (Qingyuan) Industrial Transfer Industrial Park, Shijiao Town, Qingcheng District, Qingyuan City, Guangdong Province, 511500 Patentee after: Guangdong Weixin Med Medical Products Co.,Ltd. Address before: 510000 first and fourth floors, building 2, No. 39, bigang Road, East Street, Luogang District, Guangzhou City, Guangdong Province Patentee before: GUANGZHOU MAIDI MEDICAL Co.,Ltd. |
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