CN105288738A - 一种骨细胞培养的三维微环境结构体 - Google Patents
一种骨细胞培养的三维微环境结构体 Download PDFInfo
- Publication number
- CN105288738A CN105288738A CN201510797789.2A CN201510797789A CN105288738A CN 105288738 A CN105288738 A CN 105288738A CN 201510797789 A CN201510797789 A CN 201510797789A CN 105288738 A CN105288738 A CN 105288738A
- Authority
- CN
- China
- Prior art keywords
- dimensional
- bone
- model
- osteocyte
- osseous tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y10/00—Processes of additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Materials For Medical Uses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Description
Claims (8)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510797789.2A CN105288738A (zh) | 2015-11-18 | 2015-11-18 | 一种骨细胞培养的三维微环境结构体 |
PCT/CN2016/090524 WO2017084369A1 (zh) | 2015-11-18 | 2016-07-19 | 骨细胞培养方法 |
US15/776,427 US20180340149A1 (en) | 2015-11-18 | 2016-07-19 | Method for culturing osteocyte |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510797789.2A CN105288738A (zh) | 2015-11-18 | 2015-11-18 | 一种骨细胞培养的三维微环境结构体 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105288738A true CN105288738A (zh) | 2016-02-03 |
Family
ID=55187001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510797789.2A Pending CN105288738A (zh) | 2015-11-18 | 2015-11-18 | 一种骨细胞培养的三维微环境结构体 |
Country Status (3)
Country | Link |
---|---|
US (1) | US20180340149A1 (zh) |
CN (1) | CN105288738A (zh) |
WO (1) | WO2017084369A1 (zh) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105838602A (zh) * | 2016-05-10 | 2016-08-10 | 深圳市艾科赛龙科技有限公司 | 一种制备组织的方法及装置 |
CN105868580A (zh) * | 2016-04-05 | 2016-08-17 | 西安交通大学 | 一种基于面积约束与形状约束的细胞结构三维形貌恢复方法 |
CN105912863A (zh) * | 2016-04-13 | 2016-08-31 | 深圳市艾科赛龙科技有限公司 | 一种人工骨的制备方法及*** |
CN105976425A (zh) * | 2016-04-13 | 2016-09-28 | 深圳市艾科赛龙科技有限公司 | 一种结构设计的方法及装置 |
CN106606802A (zh) * | 2016-12-06 | 2017-05-03 | 广州邦菲医疗器械科技有限公司 | 3d打印含多级通道的骨修复支架及其制造方法 |
WO2017084369A1 (zh) * | 2015-11-18 | 2017-05-26 | 深圳市艾科赛龙科技股份有限公司 | 骨细胞培养方法 |
CN113577379A (zh) * | 2021-09-10 | 2021-11-02 | 齐鲁工业大学 | 一种定向诱导骨组织分化的骨修复支架 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103150442A (zh) * | 2013-03-15 | 2013-06-12 | 常州华森医疗器械有限公司 | 数字化定制骨科植入物的制造工艺 |
CN104173123A (zh) * | 2014-08-22 | 2014-12-03 | 国家康复辅具研究中心 | 快速、可靠的人工骨假体制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8579620B2 (en) * | 2011-03-02 | 2013-11-12 | Andy Wu | Single-action three-dimensional model printing methods |
CN103393486B (zh) * | 2013-08-13 | 2015-09-02 | 华中科技大学同济医学院附属同济医院 | 利用3d打印制备待修补颅骨骨瓣的方法 |
CN103584931B (zh) * | 2013-10-23 | 2016-05-04 | 华南理工大学 | 一种仿生梯度膝关节股骨假体结构及其制造方法 |
CN103520771B (zh) * | 2013-10-23 | 2015-04-22 | 北京纪元联合生物技术有限公司 | 一种复合生物活性材料微区雕刻仿生人工骨的方法 |
CN103707507B (zh) * | 2013-12-13 | 2016-08-17 | 吉林大学 | 聚醚醚酮仿生人工骨的3d打印制造方法 |
KR20150087788A (ko) * | 2014-01-22 | 2015-07-30 | 백정환 | 환자 맞춤형 보형물 제작 방법 |
CN105031737B (zh) * | 2014-12-03 | 2018-01-30 | 北京印刷学院 | 3d打印的数字化人工骨及其制备方法 |
CN105288738A (zh) * | 2015-11-18 | 2016-02-03 | 深圳市艾科赛龙科技有限公司 | 一种骨细胞培养的三维微环境结构体 |
-
2015
- 2015-11-18 CN CN201510797789.2A patent/CN105288738A/zh active Pending
-
2016
- 2016-07-19 US US15/776,427 patent/US20180340149A1/en not_active Abandoned
- 2016-07-19 WO PCT/CN2016/090524 patent/WO2017084369A1/zh active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103150442A (zh) * | 2013-03-15 | 2013-06-12 | 常州华森医疗器械有限公司 | 数字化定制骨科植入物的制造工艺 |
CN104173123A (zh) * | 2014-08-22 | 2014-12-03 | 国家康复辅具研究中心 | 快速、可靠的人工骨假体制备方法 |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017084369A1 (zh) * | 2015-11-18 | 2017-05-26 | 深圳市艾科赛龙科技股份有限公司 | 骨细胞培养方法 |
CN105868580A (zh) * | 2016-04-05 | 2016-08-17 | 西安交通大学 | 一种基于面积约束与形状约束的细胞结构三维形貌恢复方法 |
CN105868580B (zh) * | 2016-04-05 | 2018-12-07 | 西安交通大学 | 一种基于面积约束与形状约束的细胞结构三维形貌恢复方法 |
CN105912863A (zh) * | 2016-04-13 | 2016-08-31 | 深圳市艾科赛龙科技有限公司 | 一种人工骨的制备方法及*** |
CN105976425A (zh) * | 2016-04-13 | 2016-09-28 | 深圳市艾科赛龙科技有限公司 | 一种结构设计的方法及装置 |
CN105912863B (zh) * | 2016-04-13 | 2018-08-17 | 深圳市艾科赛龙科技股份有限公司 | 一种人工骨的制备方法及*** |
CN105976425B (zh) * | 2016-04-13 | 2019-12-03 | 深圳市艾科赛龙科技股份有限公司 | 一种结构设计的方法及装置 |
CN105838602A (zh) * | 2016-05-10 | 2016-08-10 | 深圳市艾科赛龙科技有限公司 | 一种制备组织的方法及装置 |
CN106606802A (zh) * | 2016-12-06 | 2017-05-03 | 广州邦菲医疗器械科技有限公司 | 3d打印含多级通道的骨修复支架及其制造方法 |
CN113577379A (zh) * | 2021-09-10 | 2021-11-02 | 齐鲁工业大学 | 一种定向诱导骨组织分化的骨修复支架 |
CN113577379B (zh) * | 2021-09-10 | 2022-05-17 | 齐鲁工业大学 | 一种定向诱导骨组织分化的骨修复支架 |
Also Published As
Publication number | Publication date |
---|---|
US20180340149A1 (en) | 2018-11-29 |
WO2017084369A1 (zh) | 2017-05-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105288738A (zh) | 一种骨细胞培养的三维微环境结构体 | |
US11464640B2 (en) | Method of making a personalized bone graft | |
RU2427647C2 (ru) | Способ изготовления конструкции, содержащей кристаллическую целлюлозу | |
CN105617465B (zh) | 一种基于3d打印的生物支架制作方法及生物支架 | |
CN103315829B (zh) | 修复一侧下颌骨缺损超过4颗牙位个性化支架的制造方法 | |
US10400203B2 (en) | Method for producing living tissue and organ | |
CN102415920A (zh) | 用于下颌骨缺损组织工程化修复的个性化支架的制造方法 | |
CN102973334A (zh) | 颅骨组织工程支架仿生设计方法 | |
CN110403731A (zh) | 基于活细胞3d打印的组织工程仿生肝叶结构及制备方法 | |
CN106580520B (zh) | 具有pekk支撑固定单元与组织工程生长单元的下颌骨植入体制作方法及植入体 | |
CN102198022A (zh) | 一种活性细胞-水凝胶类器官结构体的立体成形方法 | |
CN104027847B (zh) | 一种附带血管网流道的人工软组织体的制造方法 | |
Kubanov et al. | Development of 3d bioprinting technology using modified natural and synthetic hydrogels for engineering construction of organs | |
CN103300946A (zh) | 修复下颌骨缺损跨过中心平面的个性化支架的制造方法 | |
CN111899346B (zh) | 可控多孔骨组织工程支架的数学建模方法 | |
CN110408539A (zh) | 大体积组织工程组织器官内部仿生血管网的构筑方法 | |
CN104398320A (zh) | 一种细胞受控组装人工喉软骨支架的方法 | |
CN106039398A (zh) | 一种具有微结构仿生人工骨支架的制备方法 | |
WO2019237061A1 (en) | A 3d bioprinted perfusable platform for high-throughput disease modeling and drug screening | |
CN103479450A (zh) | 髁突假体及其制作方法 | |
CN103948457A (zh) | 一种构建再生的神经血管化骨、软骨、关节或体表器官的方法 | |
CN109893300A (zh) | 一种基于3d扫描打印的骨骼支架制造方法 | |
CN101904775B (zh) | 一种基于球状体基本单元的类组织制造模具及制备工艺 | |
CN106350437B (zh) | 一种细胞球定位生物打印装置及方法 | |
Bibb et al. | Artificial vascularized scaffolds for 3D-tissue regeneration—a report of the ArtiVasc 3D Project |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information |
Address after: Nanshan District before the sea in Shenzhen City, Guangdong province 518002 No. 0101 Liwan Residence Du Commerce A-2211, 2213 Applicant after: Shenzhen Aike Cellon Polytron Technologies Inc Address before: Nanshan District before the sea in Shenzhen City, Guangdong province 518002 No. 0101 Liwan Residence Du Commerce A-2211, 2213 Applicant before: SHENZHEN EXCELLENT TECHNOLOGY CO., LTD. |
|
CB02 | Change of applicant information | ||
CB02 | Change of applicant information |
Address after: Nanshan District before the sea in Shenzhen City, Guangdong province 518002 No. 0101 Guangzhou Residence Du Commerce A-713 Applicant after: Shenzhen Aike Cellon Polytron Technologies Inc Address before: Nanshan District before the sea in Shenzhen City, Guangdong province 518002 No. 0101 Liwan Residence Du Commerce A-2211, 2213 Applicant before: Shenzhen Aike Cellon Polytron Technologies Inc |
|
CB02 | Change of applicant information | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160203 |
|
RJ01 | Rejection of invention patent application after publication |