CN105267577B - A kind of emplastrum and preparation method thereof for treating mumps - Google Patents

A kind of emplastrum and preparation method thereof for treating mumps Download PDF

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CN105267577B
CN105267577B CN201510677197.7A CN201510677197A CN105267577B CN 105267577 B CN105267577 B CN 105267577B CN 201510677197 A CN201510677197 A CN 201510677197A CN 105267577 B CN105267577 B CN 105267577B
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filtered
ethyl alcohol
refluxing extraction
emplastrum
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CN105267577A (en
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孙淑萍
李胜利
李康才
李梦
周伟杰
鲍堃
贺行理商
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Wannan Medical College
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Wannan Medical College
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Abstract

The invention discloses a kind of emplastrums and preparation method thereof for treating mumps, contain following substance:Cactus juicing, aloe juicing, Flos Lonicerae extractive solution, peppermint extracting solution, root bark of shaggy-fruited dittany extracting solution, wild chrysanthemum extracting solution, radix scutellariae extracting solution, aloe, borage oil, pot marigold oil, glycerine, ethylparaben, water solubility Ve, all-round emulsifier G57, ice crystal forming agent AVC, distilled water.Compared with prior art, it is provided by the invention force on it is warm-natured and, it is safe, have the effect for the treatment of mumps well using the active material in natural drug, anti-inflammation detumescence, it is clearing heat and detoxicating, promoting blood circulation and removing blood stasis, dredge parotid gland channels and collaterals it is with obvious effects.Local application, safe to use, without side-effects, penetration is strong, lasting medicine, and the present invention is used for a long time, has the effect of being obviously improved parotitis, treating both manifestation and root cause of disease makes patient far from parotitis;And have effects that prevent well.

Description

A kind of emplastrum and preparation method thereof for treating mumps
Technical field
The invention belongs to medical fields, and in particular to a kind of emplastrum and preparation method thereof for treating mumps.
Background technology
Mumps is respiratory infectious disease common in Children and teenager, has mumps virus to cause, and companion There is a parotid gland enlargement, looks deformation, surface skin is locally red, swollen, hot, pain.It is serious to cause meninx brain in addition to parotid gland swelling and pain The symptoms such as inflammation, pancreatitis.It can be infected by droplet and sneeze, and the universal easy infection of crowd is vulnerable especially for what is had Children.So it has prodigious threat to the physical and mental health of the mankind, and bring inconvenience.
For parotitis caused by traditional bacterium, is treated using antibiotic, easily cause superinfection, be unfavorable for Patient restores well.And for parotitis caused by virus, the antibiotic and sulfa drugs that generally use are invalid.And Though conventional oral Western medicine can alleviate symptom, gastrointestinal side effect is big, easily recurs.
Invention content
In order to solve the above technical problems, the present invention provides a kind of emplastrum for treating mumps, carried containing Chinese medicine Ingredient is taken, superinfection will not be caused, also there is prevention effect.
The present invention also provides a kind of preparation method of emplastrum that treating mumps, a kind for the treatment of being prepared The emplastrum of mumps is safe to use, penetration is strong, lasting medicine, medication are simple.
A kind of emplastrum for treating mumps provided by the invention, contains following raw material:
The cactus juicing is prepared by the following method:
It is appropriate to weigh cactus, 1-3 times of distilled water is added, squeezes the juice, gained liquid is with three layers of filtered through gauze to get cactus Juicing.
The aloe juicing is prepared by the following method:
It is appropriate to weigh aloe, 1-3 times of distilled water is added, squeezes the juice, gained liquid is squeezed with three layers of filtered through gauze to get to aloe Take liquid.
The Flos Lonicerae extractive solution is prepared by the following method:
Weigh that honeysuckle is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h, suction filtration, second of 75% ethyl alcohol for adding 10-15 times of weight, refluxing extraction 0.5-1.5h are filtered, and third time adds 8-10 times 75% ethyl alcohol of weight, refluxing extraction 0.5-1.5h are filtered, and filtrate merges three times, the volume concentration of filtrate to honeysuckle weight 4-6 times of g/ml, filter to obtain the final product.
The peppermint extracting solution is prepared by the following method:
It is appropriate to weigh peppermint, impregnates 0.15-0.8h, refluxing extraction three times, adds the water of 25-30 times of weight, extraction for the first time 1-2h, second of the water for adding 15-20 times of weight, extracts the water of 0.5-1.5h, third time plus 10-15 times of weight, extracts 0.5- 1.5h is filtered every time, and filtrate merges, and the volume concentration of filtrate is filtered to 4-6 times of g/ml of peppermint weight to obtain the final product.
The root bark of shaggy-fruited dittany extracting solution is prepared by the following method:
Weigh that the root bark of shaggy-fruited dittany is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h, suction filtration, second of 75% ethyl alcohol for adding 10-15 times of weight, refluxing extraction 0.5-1.5h are filtered, and third time adds 8-10 times 75% ethyl alcohol of weight, refluxing extraction 0.5-1.5h are filtered, and filtrate merges three times, the volume concentration of filtrate to root bark of shaggy-fruited dittany weight 4-6 times of g/ml, filter to obtain the final product.
The wild chrysanthemum extracting solution is prepared by the following method:
Weigh that wild chrysanthemum is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h, suction filtration, second of 75% ethyl alcohol for adding 10-15 times of weight, refluxing extraction 0.5-1.5h are filtered, and third time adds 8-10 times 75% ethyl alcohol of weight, refluxing extraction 0.5-1.5h are filtered, and 3 filtrate merges, the volume concentration of filtrate to wild chrysanthemum weight 4-6 times of g/ml, is filtered to obtain the final product.
The radix scutellariae extracting solution is prepared by the following method:
Weigh that radix scutellariae is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1- 2h is filtered, and second of 75% ethyl alcohol for adding 10-15 times of weight, refluxing extraction 0.5-1.5h is filtered, and for the third time plus 8-10 times weighs 75% ethyl alcohol of amount, refluxing extraction 0.5-1.5h are filtered, and 3 filtrate merges, the 4-6 of the volume concentration of filtrate to radix scutellariae weight Times g/ml, is filtered to obtain the final product.
A kind of preparation method of emplastrum for treating mumps provided by the invention, includes the following steps:
A) aloe 0.5-5g, borage oil 0.5-4g, pot marigold oil 0.5-5g, all-round emulsifier G570.5-6g are weighed Mixing is put into 60-85 DEG C of thermostat water bath and heats, for use as oil phase;
B) it weighs ice crystal forming agent AVC 0.2-0.8g to be added in 40-80ml distilled water, 60-85 DEG C of heating water bath, side Side stirring is heated, standing allows it to be fully swollen, for use as gel 1;
C) it weighs water-soluble Ve 0.1-1.5g to be added in 5-10ml distilled water, stirring and dissolving, it is for use as solution 2;
D) 10-20ml distilled water is measured, 60-85 DEG C of heating water bath is placed in, it is for use as water phase;
E) it waits for that oil phase is identical with water phase temperature, oil phase is added in thread shape in water phase, it is stirring while adding until being formed Uniform emulsion bases a;
F) ethylparaben 0.05-0.5g is dissolved in glycerine 1-5ml and forms solution 3;
G) cactus juicing 0.5-6g, aloe juicing 0.5-6g, Flos Lonicerae extractive solution are added into emulsion bases a 0.5-4g, peppermint extracting solution 0.5-4g, root bark of shaggy-fruited dittany extracting solution 0.5-4g, wild chrysanthemum extracting solution 0.5-4g, radix scutellariae extracting solution 0.5- 3g, solution 2, solution 3 obtain mixture 1 after being stirred 4-8min;
H) gel 1 is added into mixture 1, is coated on non-woven fabrics immediately after stirring into sticky fluid, It is put into 50-70 DEG C of baking oven and dries, cut, pack to get the emplastrum for the treatment of mumps.
Each ingredient is as follows in the present invention:
Cactus has the promoting flow of qi and blood circulation, clearing heat and detoxicating, swelling and pain relieving, can treat a variety of diseases with oral administration and external.Celestial being The palm can also enhance human immunity, eliminating inflammation and expelling toxin, apocenosis myogenic.《A Supplement to the Compendium of Materia Medica》Record the lightly seasoned cold in nature, row of cactus The removing toxic substances of gas activating blood and clearing heat, swelling and pain relieving.
Aloe has analgesic and tranquilizing effects, can eliminate pain, neuralgia, gout, muscles pain etc., oral administration and externally used aloe, Also there is analgesic effect.Aloe not only plays the role of removing toxic substances, anti-inflammatory, regeneration neoblast, moreover it is possible to enhance human body and be supported to disease Drag, and have the function of absorb heat detumescence, softening skin, holding cell viability, a variety of fungies, mould, bacterium, virus can be killed The effect of equal germs, inhibition and development of eliminating pathogen.
Honeysuckle has effects that clearing heat and detoxicating, cool blood detumescence, is suitable for the diseases such as carbuncle swells boil, and work(is immunized with improving The effect of energy, popularity parotitis have good prevention effect.According to the saying of modern medicine, honeysuckle is strong anti- Raw element.It can bring down a fever relieve inflammation or internal heat, anti-inflammatory analgetic, the but not side reaction of gastrointestinal tract.
Peppermint has effects that stimulation nervous centralis, and acting on skin has bright sense and creeping chill simultaneously, it is to sensory nerve end The tip plays the role of inhibition and paralysis again, has apparent alleviation parotitis and analgesic activity, also has to the infection of the upper respiratory tract apparent Anti-inflammatory and bacteriostasis.
Wild chrysanthemum has effects that clearing heat and detoxicating, dispersing swelling and dissipating binds, and energy removing toxic substances apocenosis, inducing diuresis for removing edema is antiviral, can be effective Eliminate swelling and pain caused by parotitis in ground.
Aloe has strong osmoticum, nutrient can be helped to penetrate into skin, has strength cleaning, antibacterial masterpiece With moreover, with anti-inflammatory, detumescence, inhibit bacterial growth, analgesic and other effects, playing and restrain skin surface pathogenic microorganisms and thin The effect of bacterium kills to human skin harmful levels of pathogens, prevents dermopathic generation.
The multiple uses such as borage oil can releive, maintenance skin can improve skin and more containing abundant linolenic acid Weight sclerosis, can reduce scytitis.
Pot marigold oil, external application have the effect of anti-inflammatory, sterilization anti-mildew, convergence, prevent festering, help to bring down a fever, and refrigerant Fall fire gas.Moreover it is possible to the effect of promoting blood circulation, mitigating parotitis swelling and pain.
Radix scutellariae has effects that removing toxicity for eliminating carbuncles, is used for pathopyretic ulcer, purging intense heat and detonicating.Clinical research radix scutellariae has and has one to germ Fixed inhibiting effect.
The root bark of shaggy-fruited dittany has the effect of heat-clearing and damp-drying drug, wind-dispelling is detoxified.《Haigoushen》Described in its can control all heat toxin wind, dislike Wind, wind sore, mange is red rotten, and musculus cutaneus is anxious, can alleviate parotitis symptom well.
In addition, ice crystal forming agent plays good thickening power;Glycerine is moisturizer, and moisturizing improves, and reduces freezing point, together When be also good skin penetration enhancer, the absorption of various both effectiveness ingredients can be effectively facilitated;Water-soluble Ve has good Antioxidation;Ethylparaben plays antisepsis.
There is a large amount for the treatment of parotitis effective component and trace element in the natural drug extracting solution of addition, and it is all Both effectiveness ingredient all embodies the anti-inflammation detumescence to parotitis, and clearing heat and detoxicating, promoting blood circulation and removing blood stasis, dredging parotid gland channels and collaterals are focused on simultaneously Improve the immunity of the human body, can play to the greatest extent to parotitis pain, shouting pain, discharge, lump optimum therapeuticing effect, it is various Both effectiveness ingredient synergistic effect solves the symptoms such as redness, the heat pain of parotitis patient, meets healthy medication theory instantly.
Compared with prior art, contain important extract component in the emplastrum for the treatment of mumps provided by the invention, Chinese medicine preparation is safe to use, penetration is strong, lasting medicine, medication are simple, and with the drug phase of traditional treatment parotitis Than this emplastrum property is stablized, and modest viscosity can notice repeatedly, and lotion is uniform, noresidue non-stimulated to skin.
Compared with prior art, it is provided by the invention treatment mumps force on it is warm-natured and, it is safe, Have the effect for the treatment of mumps well using the active material in natural drug, and with the prevention parotid gland well Scorching effect, using can prevent from being infected in time when not infected.Its anti-inflammation detumescence, clearing heat and detoxicating, promoting blood circulationization The stasis of blood dredges the with obvious effects of parotid gland channels and collaterals.Local application, safe to use, without side-effects, penetration is strong, lasting medicine, makes for a long time With the present invention, there is the effect of being obviously improved parotitis, treating both manifestation and root cause of disease makes patient far from parotitis.
Specific implementation mode
The present invention is described further with reference to specific embodiment.
Embodiment 1
A kind of emplastrum for treating mumps, contains following raw material:
A kind of preparation method of emplastrum that treating mumps, includes the following steps:
1.1 the preparation of cactus juicing
It weighs cactus 30g, 30ml distilled water is added, be placed in high-speed stirred in juice extractor and squeeze the juice 2min, gained liquid is used Three layers of filtered through gauze are to get cactus juicing.
The preparation of 1.2 aloe juicings
It weighs aloe 25g, 25ml distilled water is added, be placed in high-speed stirred in juice extractor and squeeze the juice 2min, gained liquid is with three Layer filtered through gauze is to get aloe juicing.
The preparation of 1.3 Flos Lonicerae extractive solutions
Honeysuckle 15g is weighed, for the first time plus after 75% ethyl alcohol of 18 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, Second of 75% ethyl alcohol for adding 12 times of weight, refluxing extraction 1h are filtered, and 75% ethyl alcohol of third time plus 10 times of weight, reflux carries It takes 1h, filters, 3 times filtrate merges, and the volume concentration of filtrate is filtered to 6 times of g/ml of honeysuckle weight to obtain the final product.
The preparation of 1.4 peppermint extracting solutions
It weighing peppermint 15g, impregnates 0.5h, refluxing extraction three times, for the first time plus the water of 28 times of weight, extracts 1.5h, and second Secondary plus 18 times of weight water, extracts the water of 1h, third time plus 18 times of weight, extracts 1h, filters every time, filtrate merges, filtrate Volume concentration is filtered to 6 times of g/ml of peppermint weight to obtain the final product.
The preparation of 1.5 root bark of shaggy-fruited dittany extracting solutions
Root bark of shaggy-fruited dittany 20g is weighed, for the first time plus after 75% ethyl alcohol of 18 times of weight immersion 0.5, refluxing extraction 1.5h is filtered, Second of 75% ethyl alcohol for adding 12 times of weight, refluxing extraction 1h are filtered, and 75% ethyl alcohol of third time plus 10 times of weight, reflux carries It takes 1h, filters, 3 times filtrate merges, and the volume concentration of filtrate is filtered to 5 times of g/ml of root bark of shaggy-fruited dittany weight to obtain the final product.
The preparation of 1.6 wild chrysanthemum extracting solutions
Wild chrysanthemum 20g is weighed, for the first time plus after 75% ethyl alcohol of 18 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, Second plus 12 times of 75% ethyl alcohol of weight, refluxing extraction 1h are filtered, 75% ethyl alcohol of third time plus 10 times of weight, refluxing extraction 1h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 6 times of g/ml of wild chrysanthemum weight to obtain the final product.
The preparation of 1.7 radix scutellariae extracting solutions
Radix scutellariae 20g is weighed, for the first time plus after 75% ethyl alcohol of 18 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, the Secondary plus 12 times of 75% ethyl alcohol of weight, refluxing extraction 1h are filtered, 75% ethyl alcohol of third time plus 10 times of weight, refluxing extraction 1h, It filters, 3 times filtrate merges, and the volume concentration of filtrate is filtered to 6 times of g/ml of radix scutellariae weight to obtain the final product.
The preparation of the emplastrum of 1.8 treatment mumps
A) weigh aloe 5g, borage oil 3g, pot marigold oil 3g, all can emulsifier G573g be added in beaker, be put into It is heated in 75 DEG C of thermostat water bath, it is for use as oil phase;
B) it weighs ice crystal forming agent AVC 0.8g to be added in the beaker equipped with 80ml distilled water, 75 DEG C of heating water baths, side Side stirring is heated, standing allows it to be fully swollen, for use as gel 1;
C) it weighs water-soluble Ve 0.8g to be added in 8ml distilled water, stirring and dissolving, it is for use as solution 2;
D) 15ml distilled water is measured, 75 DEG C of heating water baths are placed in, it is for use as water phase;
E) it waits for that oil phase is identical with water phase temperature, oil phase is added in thread shape in water phase, it is stirring while adding until being formed Uniform emulsion bases a;
F) ethylparaben 0.2g is dissolved in glycerine 4ml and forms solution 3;
G) cactus juicing 5g, aloe juicing 5g, Flos Lonicerae extractive solution 3g, peppermint are added into emulsion bases a to carry Liquid 3g, root bark of shaggy-fruited dittany extracting solution 3g, wild chrysanthemum extracting solution 2g, radix scutellariae extracting solution 2g, solution 2, solution 3 are taken, after being stirred 5min Obtain mixture 1;
H) gel 1 is added into mixture 1, is coated on non-woven fabrics immediately after stirring into sticky fluid, It is put into 60 DEG C of baking oven and dries, cut, pack to get a kind of emplastrum for treating mumps.
Embodiment 2
A kind of emplastrum for treating mumps, contains following raw material:
A kind of preparation method of emplastrum that treating mumps, includes the following steps:
2.1 celestial beings squeeze the preparation of extracting solution
It weighs cactus 30g, 60ml distilled water is added, be placed in high-speed stirred in juice extractor and squeeze the juice 1.5min, gained liquid With three layers of filtered through gauze to get cactus juicing.
The preparation of 2.1 aloe juicings
It weighs aloe 25g, 50ml distilled water is added, be placed in high-speed stirred in juice extractor and squeeze the juice 1.5min, gained liquid is used Three layers of filtered through gauze are to get aloe juicing.
The preparation of 2.3 Flos Lonicerae extractive solutions
Honeysuckle 15g is weighed, for the first time plus after 75% ethyl alcohol of 16 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, Second of 75% ethyl alcohol for adding 12 times of weight, refluxing extraction 1h are filtered, 75% ethyl alcohol of third time plus 8 times of weight, refluxing extraction 1h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 5 times of g/ml of honeysuckle weight to obtain the final product.
The preparation of 2.4 peppermint extracting solutions
It weighing peppermint 15g, impregnates 0.5h, refluxing extraction three times, for the first time plus the water of 26 times of weight, extracts 1.5h, and second Secondary plus 16 times of weight water, extracts the water of 1h, third time plus 12 times of weight, extracts 1h, filters every time, filtrate merges, filtrate Volume concentration is filtered to 5 times of g/ml of peppermint weight to obtain the final product.
The preparation of 2.5 root bark of shaggy-fruited dittany extracting solutions
Root bark of shaggy-fruited dittany 20g is weighed, for the first time plus after 75% ethyl alcohol of 16 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, Second of 75% ethyl alcohol for adding 12 times of weight, refluxing extraction 1h are filtered, 75% ethyl alcohol of third time plus 8 times of weight, refluxing extraction 1h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 5 times of g/ml of root bark of shaggy-fruited dittany weight to obtain the final product.
The preparation of 2.6 wild chrysanthemum extracting solutions
Wild chrysanthemum 20g is weighed, for the first time plus after 75% ethyl alcohol of 16 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, Second of 75% ethyl alcohol for adding 12 times of weight, refluxing extraction 1h are filtered, 75% ethyl alcohol of third time plus 8 times of weight, refluxing extraction 1h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 5 times of g/ml of wild chrysanthemum weight to obtain the final product.
The preparation of 2.7 radix scutellariae extracting solutions
Radix scutellariae 20g is weighed, for the first time plus after 75% ethyl alcohol of 16 times of weight immersion 0.5h, refluxing extraction 1.5h is filtered, the Secondary plus 12 times of weight 75% ethyl alcohol, refluxing extraction 1h are filtered, 75% ethyl alcohol of third time plus 8 times of weight, refluxing extraction 1h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 5 times of g/ml of radix scutellariae weight to obtain the final product.
The preparation of the emplastrum of 2.8 treatment mumps
A) weigh aloe 4g, borage oil 2g, pot marigold oil 4g, all can emulsifier G57 4g be added in beaker, put It is for use as oil phase to being heated in 80 DEG C of thermostat water baths;
B) it weighs ice crystal forming agent AVC 0.6g to be added in the beaker equipped with 60ml distilled water, 80 DEG C of heating water baths, side Side stirring is heated, standing allows it to be fully swollen, for use as gel 1;
C) it weighs water-soluble Ve 0.6g to be added in 6ml distilled water, stirring and dissolving, it is for use as solution 2;
D) 15ml distilled water is measured, 80 DEG C of heating water baths are placed in, it is for use as water phase;
E) it waits for that oil phase is identical with water phase temperature, oil phase is added in thread shape in water phase, it is stirring while adding until being formed Uniform emulsion bases a;
F) ethylparaben 0.15g is dissolved in glycerine 3ml and forms solution 3;
G) cactus juicing 6g, aloe juicing 5g, Flos Lonicerae extractive solution 4g, peppermint are added into emulsion bases a to carry Liquid 2g, root bark of shaggy-fruited dittany extracting solution 3g, wild chrysanthemum extracting solution 2g, radix scutellariae extracting solution 1g, solution 2, solution 3 are taken, after being stirred 4min Obtain mixture 1;
H) gel 1 is added into mixture 1, is coated on non-woven fabrics immediately after stirring into sticky fluid, It is put into 65 DEG C of baking oven and dries, cut, pack to get a kind of emplastrum for treating mumps.
Embodiment 3
A kind of emplastrum for treating mumps, contains following raw material:
A kind of preparation method of emplastrum that treating mumps, includes the following steps:
The preparation of 3.1 cactus juicings:
Cactus 50g is weighed, 100ml distilled water is added, is placed in juice extractor and squeezes the juice, three layers of gauze mistake of gained liquid Filter is to get cactus juicing.
The preparation of 3.2 aloe juicings:
Aloe 100g is weighed, 100ml times of distilled water is added, is placed in juice extractor and squeezes the juice, three layers of gauze mistake of gained liquid Filter is to get to aloe juicing.
The preparation of 3.3 Flos Lonicerae extractive solutions:
Weigh that honeysuckle is appropriate, for the first time plus after 75% ethyl alcohol of 19 times of weight impregnates 0.15-0.8h, refluxing extraction 1.5h, suction filtration, second of 75% ethyl alcohol for adding 13 times of weight, refluxing extraction 0.5h are filtered, and third time adds the 75% of 9 times of weight Ethyl alcohol, refluxing extraction 1.5h are filtered, and filtrate merges three times, and the volume concentration of filtrate is filtered to 6 times of g/ml of honeysuckle weight To obtain the final product.
The preparation of 3.4 peppermint extracting solutions:
Peppermint 50g is weighed, 0.15h is impregnated, refluxing extraction three times, adds the water of 27 times of weight for the first time, extracts 1h, for the second time Add the water of 17 times of weight, extract 0.5h, third time plus 14 times of weight waters, extracts 1.5h, filter every time, filtrate merges, filtrate Volume concentration is filtered to 6 times of g/ml of peppermint weight to obtain the final product.
The preparation of 3.5 root bark of shaggy-fruited dittany extracting solutions:
Root bark of shaggy-fruited dittany 100g is weighed, for the first time plus after 75% ethyl alcohol of 18 times of weight immersion 0.8h, refluxing extraction 2h is filtered, Second of 75% ethyl alcohol for adding 13 times of weight, refluxing extraction 0.5h are filtered, 75% ethyl alcohol of third time plus 10 times of weight, reflux It extracts 0.5h, filters, filtrate merges three times, and the volume concentration of filtrate is filtered to 5 times of g/ml of root bark of shaggy-fruited dittany weight to obtain the final product.
The preparation of 3.6 wild chrysanthemum extracting solutions:
Wild chrysanthemum 30g is weighed, for the first time plus after 75% ethyl alcohol of 16 times of weight immersion 0.2h, refluxing extraction 1h is filtered, the Secondary plus 13 times of weight 75% ethyl alcohol, refluxing extraction 0.5h are filtered, 75% ethyl alcohol of third time plus 9 times of weight, refluxing extraction 0.5h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 5 times of g/ml of wild chrysanthemum weight to obtain the final product.
The preparation of 3.7 radix scutellariae extracting solutions:
Radix scutellariae 40g is weighed, for the first time plus after 75% ethyl alcohol of 16 times of weight immersion 0.3h, refluxing extraction 1h is filtered, second Secondary plus 15 times of weight 75% ethyl alcohol, refluxing extraction 1.5h are filtered, 75% ethyl alcohol of third time plus 10 times of weight, refluxing extraction 1.5h is filtered, and 3 times filtrate merges, and the volume concentration of filtrate is filtered to 6 times of g/ml of radix scutellariae weight to obtain the final product.
The preparation method of the emplastrum of 3.8 treatment mumps:
A) weigh aloe 5g, borage oil 4g, pot marigold oil 2g, all can emulsifier G573g be added in beaker, be put into It is heated in 78 DEG C of thermostat water bath, it is for use as oil phase;
B) it weighs ice crystal forming agent AVC 0.7g to be added in the beaker equipped with 70ml distilled water, 78 DEG C of heating water baths, side Side stirring is heated, standing allows it to be fully swollen, for use as gel 1;
C) it weighs water-soluble Ve 0.5g to be added in 7ml distilled water, stirring and dissolving, it is for use as solution 2;
D) 20ml distilled water is measured, 78 DEG C of heating water baths are placed in, it is for use as water phase;
E) it waits for that oil phase is identical with water phase temperature, oil phase is added in thread shape in water phase, it is stirring while adding until being formed Uniform emulsion bases a;
F) ethylparaben 0.10g is dissolved in glycerine 3ml and forms solution 3;
G) cactus juicing 3g, aloe juicing 3g, Flos Lonicerae extractive solution 3g, peppermint are added into emulsion bases a to carry Liquid 3g, root bark of shaggy-fruited dittany extracting solution 4g, wild chrysanthemum extracting solution 4g, radix scutellariae extracting solution 3g, solution 2, solution 3 are taken, after being stirred 6min Obtain mixture 1;
H) gel 1 is added into mixture 1, is coated on non-woven fabrics immediately after stirring into sticky fluid, It is put into 50 DEG C of baking oven and dries, cut, pack to get a kind of emplastrum for treating mumps.
Test example 1
The physical and chemical index of embodiment 1,2,3 is as follows:
1.1 character
This product smell is fresh and clean, homogeneous, and viscosity is suitable, and skin tracing ability is good, noresidue, can paste repeatedly.
1.2 pH value inspections
A small amount of emplastrum is dipped with the pH test paper of wetting, pH value can be directly used for skin between 6-7.
1.3 irritation tests, anaphylaxis experiment
Small white mouse back cuts off hair, pastes the emplastrum that is prepared by embodiment 1,2 and 3 respectively in cutting plucked position, and do not have The position of patch is compared, no significant difference, shows that this product is nonirritant and anaphylaxis.
Emplastrum is affixed on (15-65 Sui, 50 people) face of volunteer in Example, observes after spending 30 minutes, does not send out It is red, dermexanthesis, phenomenon of blistering.
1.4 are placed at room temperature for experiment
By emplastrum in room temperature indwelling 6 months, still without corruption, spoiled situation.
1.5 therapeutic effects are investigated
Volunteer's (15-65 Sui, 50 people) with parotitis is chosen, the emplastrum obtained by embodiment 1,2 and 3 is used for At volunteer's affected skin, volunteers generally feel that sense of touch is preferable.No matter skin quality uses all without special reaction, through continuous skin A period of time uses, and swelling and pain disappear, and parotitis symptom has apparent improve.

Claims (9)

1. a kind of emplastrum for treating mumps, which is characterized in that the emplastrum of the treatment mumps is by following Raw material is made:
Aloe 0.5-5g
Borage oil 0.5-4g
Pot marigold oil 0.5-5g
Cactus juicing 0.5-6g
Aloe juicing 0.5-6g
Flos Lonicerae extractive solution 0.5-4g
Peppermint extracting solution 0.5-4g
Root bark of shaggy-fruited dittany extracting solution 0.5-4g
Wild chrysanthemum extracting solution 0.5-4g
Radix scutellariae extracting solution 0.5-3g
All-round emulsifier 0.5-6g
Glycerine 1-5ml
Ethylparaben 0.05-0.5g
Water-soluble Ve 0.1-1.5g
Ice crystal forming agent AVC 0.2-0.8g
Distilled water 55-110ml.
2. the emplastrum for the treatment of mumps according to claim 1, which is characterized in that the cactus juicing It is prepared by the following method:
It is appropriate to weigh cactus, 1-3 times of distilled water is added, squeezes the juice, gained liquid is squeezed with three layers of filtered through gauze to get cactus Liquid.
3. the emplastrum for the treatment of mumps according to claim 1 or 2, which is characterized in that the aloe is squeezed Liquid is prepared by the following method:
It is appropriate to weigh aloe, 1-3 times of distilled water is added, squeezes the juice, gained liquid is squeezed with three layers of filtered through gauze to get to aloe Liquid.
4. the emplastrum for the treatment of mumps according to claim 1 or 2, which is characterized in that the honeysuckle carries Liquid is taken to be prepared by the following method:
Weigh that honeysuckle is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h, Filter, second plus 10-15 times of weight 75% ethyl alcohol, refluxing extraction 0.5-1.5h filters, third time plus 8-10 times of weight 75% ethyl alcohol, refluxing extraction 0.5-1.5h are filtered, and filtrate merges three times, 4-6 times of the volume concentration of filtrate to honeysuckle weight G/ml is filtered to obtain the final product.
5. the emplastrum for the treatment of mumps according to claim 1 or 2, which is characterized in that the peppermint extraction Liquid is prepared by the following method:
It is appropriate to weigh peppermint, impregnates 0.15-0.8h, refluxing extraction three times, adds the water of 25-30 times of weight, extracts 1-2h for the first time, Second of the water for adding 15-20 times of weight, extracts the water of 0.5-1.5h, third time plus 10-15 times of weight, extracts 0.5-1.5h, often Secondary filtration, filtrate merge, and the volume concentration of filtrate is filtered to 4-6 times of g/ml of peppermint weight to obtain the final product.
6. the emplastrum for the treatment of mumps according to claim 1 or 2, which is characterized in that the root bark of shaggy-fruited dittany carries Liquid is taken to be prepared by the following method:
Weigh that the root bark of shaggy-fruited dittany is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h, Filter, second plus 10-15 times of weight 75% ethyl alcohol, refluxing extraction 0.5-1.5h filters, third time plus 8-10 times of weight 75% ethyl alcohol, refluxing extraction 0.5-1.5h are filtered, and filtrate merges three times, 4-6 times of the volume concentration of filtrate to root bark of shaggy-fruited dittany weight G/ml is filtered to obtain the final product.
7. the emplastrum for the treatment of mumps according to claim 1 or 2, which is characterized in that the wild chrysanthemum carries Liquid is taken to be prepared by the following method:
Weigh that wild chrysanthemum is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h, Filter, second plus 10-15 times of weight 75% ethyl alcohol, refluxing extraction 0.5-1.5h filters, third time plus 8-10 times of weight 75% ethyl alcohol, refluxing extraction 0.5-1.5h are filtered, and 3 filtrate merges, 4-6 times of g/ of the volume concentration of filtrate to wild chrysanthemum weight Ml is filtered to obtain the final product.
8. the emplastrum for the treatment of mumps according to claim 1 or 2, which is characterized in that the radix scutellariae extraction Liquid is prepared by the following method:
Weigh that radix scutellariae is appropriate, for the first time plus after 75% ethyl alcohol of 15-20 times of weight impregnates 0.15-0.8h, refluxing extraction 1-2h takes out The 75% of filter, second of 75% ethyl alcohol for adding 10-15 times of weight, refluxing extraction 0.5-1.5h, suction filtration, third time plus 8-10 times of weight Ethyl alcohol, refluxing extraction 0.5-1.5h are filtered, and 3 filtrate merges, the volume concentration of filtrate to 4-6 times of g/ml of radix scutellariae weight, mistake It filters to obtain the final product.
9. a kind of preparation method of the emplastrum of claim 1-8 any one of them treatment mumps, which is characterized in that The preparation method comprises the following steps:
a)Aloe 0.5-5g, borage oil 0.5-4g, pot marigold oil 0.5-5g, all-round emulsifier 0.5-6g mixings are weighed, is put It is for use as oil phase to being heated in 60-85 DEG C of thermostat water bath;
b)It weighs ice crystal forming agent AVC 0.2-0.8g to be added in 40-80ml distilled water, 60-85 DEG C of heating water bath, side heating Side is stirred, and standing allows it to be fully swollen, for use as gel 1;
c)It weighs water-soluble Ve 0.1-1.5g to be added in 5-10ml distilled water, stirring and dissolving, it is for use as solution 2;
d)10-20ml distilled water is measured, 60-85 DEG C of heating water bath is placed in, it is for use as water phase;
e)It waits for that oil phase is identical with water phase temperature, oil phase is added in thread shape in water phase, it is stirring while adding until being formed uniform Emulsion bases a;
f)Ethylparaben 0.05-0.5g is dissolved in glycerine 1-5ml and forms solution 3;
g)Cactus juicing 0.5-6g, aloe juicing 0.5-6g, Flos Lonicerae extractive solution 0.5- are added into emulsion bases a It is 4g, peppermint extracting solution 0.5-4g, root bark of shaggy-fruited dittany extracting solution 0.5-4g, wild chrysanthemum extracting solution 0.5-4g, radix scutellariae extracting solution 0.5-3g, molten Liquid 2, solution 3 obtain mixture 1 after being stirred 4-8min;
h)Gel 1 is added into mixture 1, is coated on non-woven fabrics, is put into immediately after stirring into sticky fluid It dries, cuts in 50-70 DEG C of baking oven, pack to get the emplastrum for the treatment of mumps.
CN201510677197.7A 2015-10-14 2015-10-14 A kind of emplastrum and preparation method thereof for treating mumps Active CN105267577B (en)

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