CN105250961A - Medicine for treating hyperplasia of mammary glands - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese preparations and provides a medicine for treating hyperplasia of mammary glands so as to solve the problem of treatment of hyperplasia of mammary glands. The medicine for treating hyperplasia of mammary glands is prepared by radix bupleuri, snakegourd fruits, fructus aurantii, pericarpium citri reticulatae viride, pericarpium citri reticulatae, citron, angelica sinensis, ligusticum wallichii, radix rehmanniae preparata, szechwan chinaberry fruits, radix curcumae, rhizoma cyperi, semen brassicae, cowherb seeds, tangerine seeds, lychee seeds, ephedra, rhizoma zingiberis, cinnamon, Chinese yam, raw hawthorns, rhizoma sparganii, curcuma zedoary and radix glycyrrhizae according to a certain proportion. Radix bupleuri, snakegourd fruits, fructus aurantii, pericarpium citri reticulatae viride and pericarpium citri reticulatae are used for soothing liver and regulating qi, citron, radix curcumae, rhizoma cyperi, cowherb seeds, angelica sinensis and ligusticum wallichii are used for activating blood, dispelling melancholy and relieving pain, ephedra, rhizoma zingiberis and cinnamon warm middle and revive yang, semen brassicae promotes circulation of qi and eliminates phlegm, radix rehmanniae preparata nourishes yin and tonifies blood, tangerine seeds and lychee seeds regulate the flow of vital energy and remove obstruction toit, Chinese yam, raw hawthorns and radix glycyrrhizae are used for harmonizing the spleen and stomach, rhizoma sparganii and curcuma zedoary are used for removing stagnate and promoting the circulation of qi. The medicine for treating hyperplasia of mammary glands can disperse accumulations and remove stagnate by soothing the liver, managing qi, activating blood and removing stasis, promote circulation of qi and eliminate phlegm, eliminate breast distending pain, and disperse hyperplastic breast lumps, thereby curing hyperplasia of mammary glands. The total effective rate reaches 94.4% or more than 94.4%.

Description

A kind of medicine for the treatment of cyclomastopathy

Technical field

The invention belongs to technical field of traditional Chinese medicine preparation, be specifically related to a kind of medicine for the treatment of cyclomastopathy.

Background technology

Cyclomastopathy is commonly encountered disease frequently-occurring disease.The caking differed in size with hypertrophy in distending pain of the breast, breast is for main clinical manifestation.Small number of patients can have faint yellow or light coffee color nipple discharge, and this type of patient's minority also can be converted into breast carcinoma, serious harm women's health.The primary disease cause of disease is that the endocrine hormone of domination mammary gland in body is disorderly, and caused by disequilibrium, minority male also has generation cyclomastopathy person.Along with modern society's rhythm of life is accelerated, life stress strengthens, and primary disease sickness rate is in rising trend.

Cyclomastopathy is called nodules of the breast in the traditional Chinese medical science.Breast master returns Liver Channel to govern, and stomach is through also following row.Depression of liver-QI is the Etiological of primary disease.Hepatic depression is tied mutually with gas, blood, expectorant for a long time and is formed breast and lump, or flat lamellar or the shape that lumps, size soft or hard not etc., depending on sick different in size.Its treatment should depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, and resolving depressionization is stagnant, and hard masses softening and resolving is main, helps with promoting the circulation of QI eliminating phlegm, makes irritability sensible, normal circulation of qi and blood, then distending pain of the breast is eliminated, the caking dissipation of hypertrophy in breast, and the endocrine of unbalance disorder tends to balance coordination, and reaches healing.

Summary of the invention

The present invention, in order to solve the treatment of cyclomastopathy, provides a kind of medicine for the treatment of cyclomastopathy.

The present invention is realized by following technical scheme: a kind of medicine for the treatment of cyclomastopathy, be made up of the raw material of following weight portion: Radix Bupleuri 10-15 part, Fructus Trichosanthis 15-25 part, Fructus Aurantii 10-20 part, Pericarpium Citri Reticulatae Viride 10-20 part, Pericarpium Citri Reticulatae 5-15 part, Fructus Citri 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Chuanxiong 10-20 part, Radix Rehmanniae Preparata 25-35 part, Fructus Toosendan 10-20 part, Radix Curcumae 10-20 part, Rhizoma Cyperi 10-20 part, Semen Sinapis Albae 10-20 part, Semen Vaccariae 15-25 part, Semen Citri Reticulatae 5-15 part, litchi nucleon 10-20 part, Herba Ephedrae 2-7 part, Rhizoma Zingiberis 2-7 part, Cortex Cinnamomi 10-20 part, Rhizoma Dioscoreae 15-25 part, Fructus Crataegi 15-25 part, Rhizoma Sparganii 10-20 part, Rhizoma Curcumae 10-20 part, Radix Glycyrrhizae 8-15 part.

Optimum ratio is: be made up of the raw material of following weight portion: Radix Bupleuri 12 parts, Fructus Trichosanthis 20 parts, Fructus Aurantii 15 parts, 15 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 10 parts, Fructus Citri 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 15 parts, 30 parts, Radix Rehmanniae Preparata, Fructus Toosendan 15 parts, Radix Curcumae 15 parts, Rhizoma Cyperi 15 parts, Semen Sinapis Albae 15 parts, Semen Vaccariae 20 parts, Semen Citri Reticulatae 10 parts, litchi nucleon 15 parts, 5 parts, Herba Ephedrae, Rhizoma Zingiberis 5 parts, Cortex Cinnamomi 15 parts, Rhizoma Dioscoreae 20 parts, Fructus Crataegi 20 parts, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, 10 parts, Radix Glycyrrhizae.

The medicine of described treatment cyclomastopathy is prepared into Chinese medicine decoction, decoction pieces, granule, oral liquid or syrup.

In Chinese medicine preparation of the present invention: Radix Bupleuri: property is bitter, is slightly cold.Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.Sweet, the micro-hardship of Fructus Trichosanthis, cold.Return lung, stomach, large intestine channel.Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.Fructus Aurantii property is bitter, pungent, sour, temperature.Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.Pericarpium Citri Reticulatae Viride is bitter, pungent, temperature.Return liver, gallbladder, stomach warp.Soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.Pericarpium Citri Reticulatae is bitter, pungent, temperature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Fructus Citri property is pungent, bitter, sour, temperature.Return liver, spleen, lung meridian.Liver-smoothing, qi-regulating, alleviating distention in middle-JIAO, reduces phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavity abdomen feeling of fullness, vomiting eructation, abundant expectoration is coughed.Radix Angelicae Sinensis sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.Rhizoma Chuanxiong is pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Radix Rehmanniae Preparata is sweet, tepor.Return liver, kidney channel.Nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.Fructus Toosendan is bitter, cold; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.Soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.Radix Curcumae property is pungent, bitter, cold.Return liver, the heart, lung meridian.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.Pungent, the micro-hardship of Rhizoma Cyperi property, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Semen Sinapis Albae is pungent; Warming the lung; Liver; Spleen; Stomach; Pericardium channel; Reduce phlegm by drink; Mass dissipating and swelling eliminating.Main cough with asthma abundant expectoration; Fullness in the chest and hypochondriac pain; Numb limbs and tense tendons; Arthralgia; Multiple abscess caused by damp-phlegm; Carbuncle of yin nature toxic swelling.Semen Vaccariae is bitter, flat.Return liver, stomach warp.Promoting blood circulation to restore menstrual flow, stimulating milk secretion is subsided a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.Semen Citri Reticulatae is bitter, flat.Return liver, kidney channel.Regulate the flow of vital energy, eliminating stagnation, pain relieving.For inguinal hernia, painful and swollen testis, acute mastitis swells and ache.Sweet, the micro-hardship of litchi nucleon, temperature.Return liver, kidney channel.Promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.For colic of cold type stomachache, painful and swollen testis.Pungent, the micro-hardship of Herba Ephedrae property, temperature.Return lung, urinary bladder channel.Diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba ephedrae nourishing the lung to arrest cough.Be used for table disease to separate, asthma and cough.Rhizoma Zingiberis property is pungent, hot.Return spleen, stomach, kidney, the heart, lung meridian.Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.Cortex Cinnamomi property is pungent, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.Rhizoma Dioscoreae property is sweet, flat.Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.Fructus Crataegi is sour, sweet, tepor.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.Rhizoma Sparganii is pungent, bitter, flat.Return liver, spleen channel.Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.Rhizoma Curcumae nature and flavor] pungent, bitter, temperature.Return liver, spleen channel.Circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.Radix Glycyrrhizae property is sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The present invention is with Radix Bupleuri, Fructus Trichosanthis, Fructus Aurantii, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae depressed liver-energy dispersing and QI regulating, Fructus Citri, Radix Curcumae, Rhizoma Cyperi, Semen Vaccariae, Radix Angelicae Sinensis, the pain relieving of Rhizoma Chuanxiong Huoxue Jieyu alleviating distention in middle-JIAO, Herba Ephedrae, Rhizoma Zingiberis, Cortex Cinnamomi warming middle-JIAO recuperating depleted YANG, Semen Sinapis Albae promoting the circulation of QI eliminating phlegm, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, Semen Citri Reticulatae, litchi nucleon are regulated the flow of vital energy eliminating stagnation, Rhizoma Dioscoreae, Fructus Crataegi, Radix Glycyrrhizae harmonizing the spleen and stomach, Rhizoma Sparganii, the circulation of qi promoting of Rhizoma Curcumae removing blood stasis with potent drugs, removing food stagnancyization is tied, by depressed liver-energy dispersing and QI regulating blood circulation promoting and blood stasis dispelling, removing food stagnancy eliminating stagnation, promoting the circulation of QI eliminating phlegm, makes distending pain of the breast eliminate, and the breast caking of hypertrophy dissipates and cures this disease.

It is as follows that Chinese medicine of the present invention is used for clinical situation: calendar year 2001 to 2014 year, and treatment cyclomastopathy 526 example, at minimum 18 years old maximum 55 years old age, the course of disease is the shortest 20 days, the longest 5 years.Age cohorts is in table 1, and course of disease grouping is in table 2, and breast caking size packets is in table 3.Patient's every day oral embodiment 2 Chinese medicine preparation, every day potion, above medicine 800ml boiled water soaks 1h, to get angry decoction, intense fire 15min, slow fire 10min, leach medicine juice 300ml, the 600ml that adds water again for the second time decocts 20min, leach medicine juice, twice medicine juice merges into 500ml, point secondary decoction being taken warmly sooner or later after mix homogeneously, be a course for the treatment of with 5 days, 1 the course for the treatment of observe the curative effect.

Table 1: age cohorts

Age

18-25

25-30

30-40

40-45

45-50

More than 50

Number of cases

94 examples

161 examples

164 examples

79 examples

22 examples

6 examples

Table 2: the course of disease is divided into groups

The course of disease

Below January

The 1-3 month

The 3-6 month

The 6-12 month

1-3

More than 3 years

Number of cases

96 examples

154 examples

131 examples

105 examples

25 examples

15 examples

Table 3: breast caking size packets

Lump in breast size	Below 3cm	3-5cm	5-8cm	More than 8cm
					Number of cases	21 examples	273 examples	210 examples	22 examples

Diagnosis basis: according to the regulation of " People's Republic of China's traditional Chinese medicine industry standard---Chinese medical disease Standardization of diagnosis and curative effect (ZY/T001.1-94) ", with reference to " the diagnosis basis of nodules of the breast ",most have a flat lump at the outside upper quadrant of breast, and that lays one's hand on has the tough hard tubercle of beans size, can have tenderness.Lump border owes clear, with surrounding tissue adhesion.Breast can have distending pain, the often growth and decline with susceptible to anger, and the moon of being everlasting is premenstrual to be increased the weight of, and alleviates after menstruation.Primary disease is more common in 20 ~ 40 years old women.Molybdenum palladium x-ray breast is taken the photograph sheet, cold light source strong illumination, liquid crystal thermography picture etc. inspections and is helped diagnosis.Make histopathological examination if desired.

Syndrome-classification: according to the regulation of " People's Republic of China's traditional Chinese medicine industry standard---Chinese medical disease Standardization of diagnosis and curative effect (ZY/T001.1-94) ", with reference to " nodules of the breastsyndrome-classification ", liver energy depression and phlegm stagnation: be more common between twenty and fifty women.Lump in breast, with susceptible to anger growth and decline, with feeling of oppression over the chest and distention of hypochondrium, is apt to strongly fragrant irritability, insomnia and dreamful sleep, vexed bitter taste.Tongue fur BOHUANG, stringy and rolling pulse.Chong and Ren channel disorder: be more common in middle-aged women.The lump in breast moon is premenstrual to be increased the weight of, through after extenuate.Weak with the soreness of waist, tired, menstruation is imbalance successively, and the few color of amount is light, or amenorrhea.Light red tongue, tongue is white, deep-thready pulse.

Efficacy evaluation: according to the regulation of " People's Republic of China's traditional Chinese medicine industry standard---Chinese medical disease Standardization of diagnosis and curative effect (ZY/T001.1-94) ", with reference to " nodules of the breastefficacy evaluation ", cure: lump in breast and pain disappear; Soft breast recovers normal.Take a turn for the better: distending pain of the breast disappears, breast caking is basic to disappear, and slightly can touch vestige.Do not heal: distending pain of the breast alleviates before and after menstruation and still has pain; Breast caking slightly diminishes or does not substantially become.

Therapeutic Method: get Radix Bupleuri 12g, Fructus Trichosanthis 20g, Fructus Aurantii 15g, Pericarpium Citri Reticulatae Viride 15g, Pericarpium Citri Reticulatae 10g, Fructus Citri 15g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 15g, Radix Rehmanniae Preparata 30g, Fructus Toosendan 15g, Radix Curcumae 15g, Rhizoma Cyperi 15g, Semen Sinapis Albae 15g, Semen Vaccariae 20g, Semen Citri Reticulatae 10g, litchi nucleon 15g, Herba Ephedrae 5g, Rhizoma Zingiberis 5g, Cortex Cinnamomi 15g, Rhizoma Dioscoreae 20g, Fructus Crataegi 20g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g, Radix Glycyrrhizae 10g.Above medicine 800ml boiled water soaks 1h, to get angry decoction, intense fire 15min, slow fire 10min, leach medicine juice 300ml, the 600ml that adds water again for the second time decocts 20min, leach medicine juice, twice medicine juice merges into 500ml, point secondary decoction being taken warmly sooner or later after mix homogeneously, be a course for the treatment of with 5 days, 1 the course for the treatment of observe the curative effect.

Therapeutic outcome is in table 4, and total effective rate reaches 96%, follows up a case by regular visits to 1 year, and recurrence 19 example, relapse rate is 3.6%.

Table 4: therapeutic outcome

Cure	Take a turn for the better	Do not heal
			457 examples	47	22
87%	9%	4%

Model case

1. Wu, female 32 years old, went to a doctor on July 3rd, 2014, readme mastalgia is had a surplus March, the distending pain when initial stage, menstruation came, gradually to shaking also pain at ordinary times on foot by bike, check that left breast outside upper quadrant 4 × 7cm breast lumps, touch a tender spot obviously, above right breast, 3 × 4cm breast caking touches pain, and infrared breast examination bilateral breast vascularity is without exception, breast caking position transmittance reduces, in grey dark space, bilateral breast caking is movable, with surrounding tissue without involving.Be diagnosed as cyclomastopathy right Ruzhong degree, left newborn severe.Take medicine described in the embodiment of the present invention 29 days, breast not pain, continue to take and within 20 days, check that bilateral lump in breast dissipates completely, recovers normal, follows up a case by regular visits to and do not recur so far afterwards.

2. Bai, female 24 years old, go to a doctor on August 19th, 2013, readme is: distending pain of the breast 1 year, and distending pain before initial stage menstruation comes, gradually increase the weight of, breast internal medicine touches lump, once takes RUPIXIAO DeGrain.Check: touch a tender spot obviously above breast, 3 × 3cm on the right side of lump in breast, left side 2 × 2cm, above infrared inspection breast, transmittance is poor, the ash dark space in small pieces, vascularity is without exception.Be diagnosed as slight cyclomastopathy, take the distending pain disappearance after 10 days of medicine described in the embodiment of the present invention 2, continue to take 10 days lumps and all disappear, breast recovers normal, follows up a case by regular visits to and does not recur so far.

3. Zhang, female 33 years old, went to a doctor on August 1st, 2012, readme: mastalgia is had a surplus for 1 year, once take breast and increase the five secondary pain only drug withdrawals that disappear, the present is pain again, check: 6 × 6cm lump on the right side of breast, left side 6 × 8cm, in flat lamellar, touch a tender spot obviously, be diagnosed as cyclomastopathy, take the 5 days distending pains of medicine described in the embodiment of the present invention 2 and eliminate, continue to take 10 days RUKUAIXIAO and remove, breast recovers normal, follows up a case by regular visits to and does not recur so far.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is described in further detail.

Embodiment 1: a kind of medicine for the treatment of cyclomastopathy, is made up of the raw material of following weight proportion: Radix Bupleuri 10g, Fructus Trichosanthis 15g, Fructus Aurantii 10g, Pericarpium Citri Reticulatae Viride 10g, Pericarpium Citri Reticulatae 5g, Fructus Citri 10g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, Radix Rehmanniae Preparata 25g, Fructus Toosendan 10g, Radix Curcumae 10g, Rhizoma Cyperi 10g, Semen Sinapis Albae 10g, Semen Vaccariae 15g, Semen Citri Reticulatae 5g, litchi nucleon 10g, Herba Ephedrae 2g, Rhizoma Zingiberis 2g, Cortex Cinnamomi 10g, Rhizoma Dioscoreae 15g, Fructus Crataegi 15g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Radix Glycyrrhizae 8g.Described medicine is made decoction pieces, decoction being taken warmly, every day 2, with 10 days courses for the treatment of, 1 the course for the treatment of observe the curative effect.The present embodiment institute pharmacy, same adopts above-mentioned diagnosis basis, criterion of therapeutical effect and Therapeutic Method to carry out clinical trial, treats, therapeutic outcome to 80 patients: healing person 50 example accounts for 62.5%, improvement person 26 example accounts for 32.5%, non-healing person 4 example accounts for 5%.Total effective rate reaches 95%.

Embodiment 2: a kind of medicine for the treatment of cyclomastopathy, is made up of the raw material of following weight proportion: Radix Bupleuri 12g, Fructus Trichosanthis 20g, Fructus Aurantii 15g, Pericarpium Citri Reticulatae Viride 15g, Pericarpium Citri Reticulatae 10g, Fructus Citri 15g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 15g, Radix Rehmanniae Preparata 30g, Fructus Toosendan 15g, Radix Curcumae 15g, Rhizoma Cyperi 15g, Semen Sinapis Albae 15g, Semen Vaccariae 20g, Semen Citri Reticulatae 10g, litchi nucleon 15g, Herba Ephedrae 5g, Rhizoma Zingiberis 5g, Cortex Cinnamomi 15g, Rhizoma Dioscoreae 20g, Fructus Crataegi 20g, Rhizoma Sparganii 15g, Rhizoma Curcumae 15g, Radix Glycyrrhizae 10g.Above medicine 800ml boiled water soaks 1h, to get angry decoction, intense fire 15min, slow fire 10min, leach medicine juice 300ml, the 600ml that adds water again for the second time decocts 20min, leach medicine juice, twice medicine juice merges into 500ml, point secondary decoction being taken warmly sooner or later after mix homogeneously, be a course for the treatment of with 5 days, 1 the course for the treatment of observe the curative effect.

Embodiment 3: a kind of medicine for the treatment of cyclomastopathy, is made up of the raw material of following weight proportion: Radix Bupleuri 15g, Fructus Trichosanthis 25g, Fructus Aurantii 20g, Pericarpium Citri Reticulatae Viride 20g, Pericarpium Citri Reticulatae 15g, Fructus Citri 20g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 20g, Radix Rehmanniae Preparata 35g, Fructus Toosendan 20g, Radix Curcumae 20g, Rhizoma Cyperi 20g, Semen Sinapis Albae 20g, Semen Vaccariae 25g, Semen Citri Reticulatae 15g, litchi nucleon 20g, Herba Ephedrae 7g, Rhizoma Zingiberis 7g, Cortex Cinnamomi 20g, Rhizoma Dioscoreae 25g, Fructus Crataegi 25g, Rhizoma Sparganii 20g, Rhizoma Curcumae 20g, Radix Glycyrrhizae 15g.Granule made by described medicine, one day 1 dose, be a course for the treatment of with 5 days, 1 the course for the treatment of observe the curative effect.The present embodiment institute pharmacy, same adopts above-mentioned diagnosis basis, criterion of therapeutical effect and Therapeutic Method to carry out clinical trial, treats, therapeutic outcome to 90 patients: healing person 63 example accounts for 70%, improvement person 22 example accounts for 24.4%, non-healing person 5 example accounts for 5.6%.Total effective rate reaches 94.4%.

Claims (3)

1. treat the medicine of cyclomastopathy for one kind, it is characterized in that: be made up of the raw material of following weight portion: Radix Bupleuri 10-15 part, Fructus Trichosanthis 15-25 part, Fructus Aurantii 10-20 part, Pericarpium Citri Reticulatae Viride 10-20 part, Pericarpium Citri Reticulatae 5-15 part, Fructus Citri 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Chuanxiong 10-20 part, Radix Rehmanniae Preparata 25-35 part, Fructus Toosendan 10-20 part, Radix Curcumae 10-20 part, Rhizoma Cyperi 10-20 part, Semen Sinapis Albae 10-20 part, Semen Vaccariae 15-25 part, Semen Citri Reticulatae 5-15 part, litchi nucleon 10-20 part, Herba Ephedrae 2-7 part, Rhizoma Zingiberis 2-7 part, Cortex Cinnamomi 10-20 part, Rhizoma Dioscoreae 15-25 part, Fructus Crataegi 15-25 part, Rhizoma Sparganii 10-20 part, Rhizoma Curcumae 10-20 part, Radix Glycyrrhizae 8-15 part.

2. a kind of medicine for the treatment of cyclomastopathy according to claim 1, is characterized in that: be made up of the raw material of following weight portion: Radix Bupleuri 12 parts, Fructus Trichosanthis 20 parts, Fructus Aurantii 15 parts, 15 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 10 parts, Fructus Citri 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 15 parts, 30 parts, Radix Rehmanniae Preparata, Fructus Toosendan 15 parts, Radix Curcumae 15 parts, Rhizoma Cyperi 15 parts, Semen Sinapis Albae 15 parts, Semen Vaccariae 20 parts, Semen Citri Reticulatae 10 parts, litchi nucleon 15 parts, 5 parts, Herba Ephedrae, Rhizoma Zingiberis 5 parts, Cortex Cinnamomi 15 parts, Rhizoma Dioscoreae 20 parts, Fructus Crataegi 20 parts, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, 10 parts, Radix Glycyrrhizae.

3. a kind of medicine for the treatment of cyclomastopathy according to claim 1 and 2, is characterized in that: the medicine of described treatment cyclomastopathy is prepared into Chinese medicine decoction, decoction pieces, granule, oral liquid or syrup.