CN105250915A - Traditional Chinese medicine composition for treating myocarditis - Google Patents
Traditional Chinese medicine composition for treating myocarditis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating myocarditis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 2-4 parts of coptis root, 15-30 parts of codonopsis pilosula, 12-15 parts of dwarf lilyturf tuber, 25-35 parts of danshen root, 15-30 parts of coastal glehnia root, 9-12 parts of figwort root, 3-5 parts of Chinese magnoliavine fruit, 10-14 parts of turmeric root-tuber, 5-9 parts of rosewood heart wood, 5-9 parts of snakegourd peel and 8-12 parts of light yellow sophora root. The traditional Chinese medicine composition disclosed by the invention adopts multiple Chinese medicinal herbs in compatibility, is low in cost, reasonable in formula and better in medicine effect exertion, does not have toxic or side effects, and has the effects of supplementing qi and nourishing yin, reducing phlegm and removing blood stasis, as well as clearing away heart-fire and calming down heart palpitation. The traditional Chinese medicine composition has a marked effect in treating patients with myocarditis, and deficiency of both qi and yin and turbid phlegm caused by obstruction of qi in the chest, including the symptoms of chest distress, palpitation, dysphoria, short breath, non-steadfast sleeping, dizziness, hypodynamia, hyperhidrosis, red tongue tip and the like. The traditional Chinese medicine composition disclosed by the invention is especially very good in curative effect of treating viral myocarditis, and a clinical pharmacodynamic test proves that the traditional Chinese medicine composition disclosed by the invention has the cure rate of 79% and the total effective rate of close to 100% for treating viral myocarditis.
Description
Technical field
The present invention relates to Chinese medicine composition, specifically one treats myocarditic Chinese medicine composition.
Background technology
Myocarditis refers to the Lymph nodes of the cardiac muscle caused because of a variety of causes.The relative incidence rate of viral myocarditis constantly increases in recent years.State of an illness weight is different, and clinical manifestation is different, and patient with slight symptoms is without any symptom, and patient with severe symptoms heart failure can occur, cardiogenic shock is even died suddenly.
The myocarditic cause of disease can be divided into following several:
1. infectious factors: virus is as Coxsackie virus, ECHO virus, influenza virus, adenovirus, hepatitis virus etc.; Antibacterial is as diphtheria corynebacterium, streptococcus etc.; Fungus; Rickettsia; Spirillum; Protozoon etc.Wherein viral myocarditis is the most common; 2. autoimmune disease: as systemic lupus erythematosus (sle), giant cell myocarditis; 3. physical factor: as breast radiation treats the myocardial damage caused; 4. chemical factor: if multi-medicament is as some antibiotics, tumor chemotherapeutic drug etc.
Myocarditis does not also have special Therapeutic Method at present, mainly emphasizes to lie up, to alleviate heart burden and tissue injury.Some immunosuppressant does not obtain consistent clinical efficacy of generally acknowledging, therefore does not recommend conventional application.The application of hormone still has arguement.
Summary of the invention
Technical problem to be solved by this invention be to provide a kind of cost low, have no side effect, the myocarditic Chinese medicine composition for the treatment of evident in efficacy.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme: one treats myocarditic Chinese medicine composition, by weight, following raw material is comprised: Rhizoma Coptidis 2-4, Radix codonopsis pilosulae (Radix Codonopsis) 15-30, Radix Ophiopogonis 12-15, Radix Salviae Miltiorrhizae 25-35, Radix Glehniae 15-30, Radix Scrophulariae 9-12, Fructus Schisandrae Chinensis 3-5, Radix Curcumae 10-14, Lignum Dalbergiae Odoriferae 5-9, Pericarpium Trichosanthis 5-9, Radix Sophorae Flavescentis 8-12.
Preferably, the weight portion of each raw material is: Rhizoma Coptidis 3, Radix codonopsis pilosulae (Radix Codonopsis) 22, Radix Ophiopogonis 13, Radix Salviae Miltiorrhizae 30, Radix Glehniae 23, Radix Scrophulariae 11, Fructus Schisandrae Chinensis 4, Radix Curcumae 12, Lignum Dalbergiae Odoriferae 7, Pericarpium Trichosanthis 7, Radix Sophorae Flavescentis 10.
Preferably, the weight portion of each raw material is: Rhizoma Coptidis 2, Radix codonopsis pilosulae (Radix Codonopsis) 15, Radix Ophiopogonis 12, Radix Salviae Miltiorrhizae 25, Radix Glehniae 15, Radix Scrophulariae 9, Fructus Schisandrae Chinensis 3, Radix Curcumae 10, Lignum Dalbergiae Odoriferae 5, Pericarpium Trichosanthis 5, Radix Sophorae Flavescentis 8.
Preferably, the weight portion of each raw material is: Rhizoma Coptidis 4, Radix codonopsis pilosulae (Radix Codonopsis) 30, Radix Ophiopogonis 15, Radix Salviae Miltiorrhizae 35, Radix Glehniae 30, Radix Scrophulariae 12, Fructus Schisandrae Chinensis 5, Radix Curcumae 14, Lignum Dalbergiae Odoriferae 9, Pericarpium Trichosanthis 9, Radix Sophorae Flavescentis 12.
The present invention treats myocarditic Chinese medicine composition and can decoct into decoction by Chinese medicine method and take.
The present invention also provides a kind of pharmaceutical preparation, comprises the myocarditic Chinese medicine composition of described treatment and pharmaceutically acceptable carrier or excipient.For the present invention, first the myocarditic Chinese medicine composition for the treatment of to be carried out the extraction of active component through this area conventional extraction techniques sedimentation as pure in water extraction or the alcohol extracting-water precipitating method of falling, then active component is combined with pharmaceutically acceptable carrier or excipient, pharmaceutically acceptable carrier or excipient are selected according to different dosage forms, and these carriers used or excipient can determine for those of ordinary skill in the art.Making pharmaceutical preparation can facilitate patient to take.
Preferably, described pharmaceutical preparation is capsule, tablet or pill.
Rhizoma Coptidis in the present invention, bitter in the mouth cold in nature, belongs to the key medicine controlling damp-heat in middle-JIAO, has the function of dampness heat clearing away, eliminating fire and detoxication.
Radix codonopsis pilosulae (Radix Codonopsis), sweet in the mouth, property is put down.Have invigorating the spleen and replenishing QI, quench the thirst, effect of spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, interior-heat is quenched one's thirst, lazy speech is losed heart, myasthenia of limbs, be off one's feed, the deficiency of vital energy, gas Tianjin two are empty, QI and blood is two loses and the disease such as blood deficiency and yellow complexion.
Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature, return stomach, lung, heart channel, has nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the effect of the relieving restlessness that clears away heart-fire.Cough for dryness of the lung dry cough, deficiency of YIN consumptive disease, sore throat pharyngalgia, Tianjin wound be thirsty, interior-heat is quenched one's thirst, vexed insomnia, the disease such as dryness of the intestine constipation.Modern pharmacological research also shows, has calmness, hypnosis Radix Ophiopogonis, resists myocardial ischemia, the effect such as arrhythmia, antitumor.
Radix Salviae Miltiorrhizae, bitter in the mouth, is slightly cold, GUIXIN, Liver Channel.There is effect of blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, the relieving restlessness that clears away heart-fire, removing heat from blood eliminating carbuncle.Gather for obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass, the disease such as pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swell and ache.
Radix Glehniae, cold nature, sweet in the mouth, micro-hardship, have foster lung yin, clearing away lung-heat, effect of expelling phlegm for arresting cough, diseases such as curing mainly nourishing YIN and clearing away lung-heat, expelling phlegm for arresting cough, control lung-heat type cough, chronic consumptive disease chronic cough, the moon hinder dry pharynx, be thirsty.
Radix Scrophulariae, cold nature, have clearing away heat and cooling blood. effect of replenishing YIN and removing heat, eliminating fire and detoxication, hard masses softening and resolving.Cure mainly warm febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, the diseases such as constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula sucutaneous nodule, skin sore are not hindered in awake, Tianjin to send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency.
Fructus Schisandrae Chinensis, have astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission effect.Cure mainly the diseases such as the deficiency of the lung is breathed with cough, xerostomia is done yearningly, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.
Radix Curcumae, property is pungent, bitter, cold.There is effect of promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.Go mad for the twinge of the breast side of body, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, distending pain of the breast, calentura coma, epilepsy, heat in blood tells the disease such as nosebleed, jaundice dark coloured urine.
Lignum Dalbergiae Odoriferae, property is pungent, warm, has removing stasis to stop bleeding, effect of regulating QI to relieve pain.For haematemesis, epistaxis, traumatic hemorrhage, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, fall and flutter the disease such as the pain of injury, vomiting stomachache.
Pericarpium Trichosanthis, property is sweet, cold, has effect of moistening the lung and resolving phlegm, promoting the circulation of QI the chest stuffiness relieving.Cure mainly phlegm-heat cough, pharyngalgia, chest pain, haematemesis, epistaxis, quench one's thirst, constipation, the disease such as carbuncle pyogenic infections from tumour or sore.
Radix Sophorae Flavescentis, property is bitter, cold, has effect of heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, the disease such as jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, trichomonal vaginitis.
The advantage that the present invention treats myocarditic Chinese medicine composition is:
The present invention uses Chinese medicine medicines compatibility, and cost is low, and formula is reasonable, and drug effect plays good, has no side effect, and has supplementing QI and nourishing YIN, eliminating phlegm blood stasis dispelling, clear away heart-fire the effect such as surely to throb with fear.Cure mainly myocarditis, the deficiency of both QI and YIN of the thoracic obstruction is held concurrently expectorant turbid silt band person.Disease sees uncomfortable in chest, cardiopalmus, vexed, breathe hard, unreal, dizzy, weak, the hyperhidrosis of sleeping, red tip of the tongue etc.The present invention especially has extraordinary curative effect to viral myocarditis, verifies through the clinical test of pesticide effectiveness, and the present invention is to the cure rate of viral myocarditis up to 79%, and total effective rate is close to 100%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
The various raw materials that following examples use, as being not specifically noted, are commercially available prod well known in the art.
Embodiment 1
One treats myocarditic Chinese medicine composition, by weight, comprises following raw material: Rhizoma Coptidis 3g, Radix codonopsis pilosulae (Radix Codonopsis) 22g, Radix Ophiopogonis 13g, Radix Salviae Miltiorrhizae 30g, Radix Glehniae 23g, Radix Scrophulariae 11g, Fructus Schisandrae Chinensis 4g, Radix Curcumae 12g, Lignum Dalbergiae Odoriferae 7g, Pericarpium Trichosanthis 7g, Radix Sophorae Flavescentis 10g.
Embodiment 2
One treats myocarditic Chinese medicine composition, by weight, comprises following raw material: Rhizoma Coptidis 2g, Radix codonopsis pilosulae (Radix Codonopsis) 15g, Radix Ophiopogonis 12g, Radix Salviae Miltiorrhizae 25g, Radix Glehniae 15g, Radix Scrophulariae 9g, Fructus Schisandrae Chinensis 3g, Radix Curcumae 10g, Lignum Dalbergiae Odoriferae 5g, Pericarpium Trichosanthis 5g, Radix Sophorae Flavescentis 8g.
Embodiment 3
One treats myocarditic Chinese medicine composition, by weight, comprises following raw material: Rhizoma Coptidis 4g, Radix codonopsis pilosulae (Radix Codonopsis) 30g, Radix Ophiopogonis 15g, Radix Salviae Miltiorrhizae 35g, Radix Glehniae 30g, Radix Scrophulariae 12g, Fructus Schisandrae Chinensis 5g, Radix Curcumae 14g, Lignum Dalbergiae Odoriferae 9g, Pericarpium Trichosanthis 9g, Radix Sophorae Flavescentis 12g.
Embodiment 4
The clinical test of pesticide effectiveness
MethodsThe cases enrolled: more than 18 years old, through the patient being diagnosed as viral myocarditis, have viral myocarditis clinical symptoms one or more;
Usage and dosage is: the myocarditic Chinese medicine composition of a secondary treatment is placed in pottery, add cold water to exceeding medical surfaces 4-6cm, soak half an hour, then after boiling with high heat, again with slow fire boiling 30-35min, the medicinal liquid decocted by head leaches down in bowl, add water in filtering residue again and exceed medicinal residues surface 3-4cm, again with slow fire boiling about 20min, the medicinal liquid decocted two leaches, the medicinal liquid decocted with head merges, as potion, patient takes potion day, night takes, it within 7 days, is a course for the treatment of, the formula provided using embodiment 1 to embodiment 3 is as the dosage of 1 auxiliary medicine,
Curative effect situation criterion: 1. cure.Malaise symptoms disappears completely; 2. effective.Malaise symptoms alleviates or partial disappearance; 3. invalid.Malaise symptoms is unchanged.
Table 1 is the clinical pharrnacokinetics report of 300 routine Patients with Viral Myocarditis.
Table 1
| Group | To take medicine number | Healing number | Efficiently individual quantity | Invalid number | Cure rate | Total effective rate |
| Embodiment 1 | 100 | 79 | 20 | 1 | 79％ | 99％ |
| Embodiment 2 | 100 | 67 | 31 | 2 | 67％ | 98％ |
| Embodiment 3 | 100 | 74 | 25 | 1 | 74％ | 99％ |
Model case is as follows:
Lee, man, 21 years old, in sick 1 year age, patient was out of breath, severe pain uncomfortable in chest, profuse sweating, cardiac arrhythmia, light red tongue, white and thin fur.Electrocardio illustrates: sinus tachycardia, to ventricular premature contraction, is viral myocarditis after diagnosing.Take the present invention and treat myocarditic Chinese medicine composition, after treating 1 course for the treatment of, symptom is clearly better, and severe pain uncomfortable in chest alleviates, and perspire normal, tongue, tongue color take a turn for the better, and continue to take, and after 5 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Zheng, female, 35 years old, in sick 4 years ages, patient was uncomfortable in chest, cardiopalmus, breathes hard, and sleeps unreal, and light red tongue point is red.Electrocardio illustrates: early, premature ventricular beat, is diagnosed as myocarditis in the room of taking place frequently.Take the present invention and treat myocarditic Chinese medicine composition, after treating 2 courses for the treatment of, symptom is clearly better, and sensation of oppression over the chest with shortness of breath alleviates, and sleep takes a turn for the better, and tongue, tongue color take a turn for the better, and continue to take, and after 10 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Zhu, man, 30 years old, in sick 3 years ages, patient was uncomfortable in chest, and dizzy, vexed, time breathes hard, and the tip of the tongue is light red.Electrocardio illustrates: sinus rhythm, accidental ventricular premature contraction, is diagnosed as viral myocarditis.Take the present invention and treat myocarditic Chinese medicine composition, after treating for one and half courses for the treatment of, symptom is clearly better, and dizziness uncomfortable in chest alleviates, ataraxia, and tongue, tongue color take a turn for the better, and continue to take, and after 8 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Permitted certain, man, 42 years old, sick 2 years ages, patient's cardiopalmus, uncomfortable in chest, breathe hard, very weak, tongue is dark red, and tongue is yellow in vain, and rolling pulse rule is uneven.Electrocardio illustrates: early, arrhythmia, is diagnosed as viral myocarditis in the room of taking place frequently.Take the present invention and treat myocarditic Chinese medicine composition, after treating 2 courses for the treatment of, symptom is clearly better, and the rhythm of the heart turns steady, cardiopalmus is uncomfortable in chest to be alleviated, and strength increases, and tongue, tongue color take a turn for the better, and continue to take, after 11 courses for the treatment of, recovery from illness, has no any side effect, follows up a case by regular visits to without recurrence after half a year.
Ma, female, 45 years old, in sick 5 years ages, patient's cardiopalmus, shortness of breath and fatigue, hyperhidrosis, slept less, consciously sharply to beat in the heart, dysphoria.Electrocardio illustrates: sinus rhythm, arrhythmia, is diagnosed as viral myocarditis.Take the present invention and treat myocarditic Chinese medicine composition, after treating 3 courses for the treatment of, symptom is clearly better, and cardiopalmus alleviates, and strength increases, sleep takes a turn for the better, and continues to take, after 12 courses for the treatment of, and most of transference cure, conscious even-tempered and good-humoured, hyperhidrosis transference cure, only accidental cardiopalmus, have no any side effect.
Be to be understood that example as herein described and embodiment only in order to illustrate, those skilled in the art can make various amendment or change according to it, when not departing from spirit of the present invention, all belong to protection scope of the present invention.
Claims (7)
1. the myocarditic Chinese medicine composition for the treatment of, by weight, following raw material is comprised: Rhizoma Coptidis 2-4, Radix codonopsis pilosulae (Radix Codonopsis) 15-30, Radix Ophiopogonis 12-15, Radix Salviae Miltiorrhizae 25-35, Radix Glehniae 15-30, Radix Scrophulariae 9-12, Fructus Schisandrae Chinensis 3-5, Radix Curcumae 10-14, Lignum Dalbergiae Odoriferae 5-9, Pericarpium Trichosanthis 5-9, Radix Sophorae Flavescentis 8-12.
2. treat a myocarditic Chinese medicine composition, by weight, comprise following raw material: Rhizoma Coptidis 3, Radix codonopsis pilosulae (Radix Codonopsis) 22, Radix Ophiopogonis 13, Radix Salviae Miltiorrhizae 30, Radix Glehniae 23, Radix Scrophulariae 11, Fructus Schisandrae Chinensis 4, Radix Curcumae 12, Lignum Dalbergiae Odoriferae 7, Pericarpium Trichosanthis 7, Radix Sophorae Flavescentis 10.
3. treat a myocarditic Chinese medicine composition, by weight, comprise following raw material: Rhizoma Coptidis 2, Radix codonopsis pilosulae (Radix Codonopsis) 15, Radix Ophiopogonis 12, Radix Salviae Miltiorrhizae 25, Radix Glehniae 15, Radix Scrophulariae 9, Fructus Schisandrae Chinensis 3, Radix Curcumae 10, Lignum Dalbergiae Odoriferae 5, Pericarpium Trichosanthis 5, Radix Sophorae Flavescentis 8.
4. treat a myocarditic Chinese medicine composition, by weight, comprise following raw material: Rhizoma Coptidis 4, Radix codonopsis pilosulae (Radix Codonopsis) 30, Radix Ophiopogonis 15, Radix Salviae Miltiorrhizae 35, Radix Glehniae 30, Radix Scrophulariae 12, Fructus Schisandrae Chinensis 5, Radix Curcumae 14, Lignum Dalbergiae Odoriferae 9, Pericarpium Trichosanthis 9, Radix Sophorae Flavescentis 12.
5. a pharmaceutical preparation, comprises the myocarditic Chinese medicine composition for the treatment of according to claim 1 and pharmaceutically acceptable carrier or excipient.
6. pharmaceutical preparation as claimed in claim 5, is characterized in that: described pharmaceutical preparation is capsule, tablet or pill.
7. the application of the myocarditic Chinese medicine composition for the treatment of as claimed in claim 1 in treatment viral myocarditis medicine.
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Cited By (1)
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| CN106729592A (en) * | 2017-03-24 | 2017-05-31 | 张安吉 | One kind detoxicating nourishing heart Chinese medicine composition and preparation method thereof |
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Application publication date: 20160120 |