CN105250787A - Medicine for treating depression of old people - Google Patents
Medicine for treating depression of old people Download PDFInfo
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- CN105250787A CN105250787A CN201510795486.7A CN201510795486A CN105250787A CN 105250787 A CN105250787 A CN 105250787A CN 201510795486 A CN201510795486 A CN 201510795486A CN 105250787 A CN105250787 A CN 105250787A
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Abstract
The invention relates to medicine for treating depression of old people. The medicine is prepared from, by weight, 1 part of Chinese ladiestresses roots or herbs, 6 parts of Chinese ephedra roots, 10 parts of spina date seeds, 6 parts of concretio silicea bambusae, 1 part of radix physochlainae, 8 parts of platycladi seeds, 10 parts of cortex albiziae, 1 part of benzoin and 10 parts of liriope spicata. According to the medicine, the Chinese ladiestresses roots or herbs nourish yin and tonify qi, the Chinese ephedra roots clam the mind and arrest sweating, the spina date seeds calm the nerves and arrest sweating, the concretio silicea bambusae clears heat and eliminates phlegm, the radix physochlainae soothes the nerves and relieves convulsion, the platycladi seeds tranquilize mind by nourishing the heart, the cortex albiziae resolves stagnation for tranquilization, the benzoin restores mental clarity and refreshes the mind, and the liriope spicata moistens the lungs and clears away the heart fire. All the ingredients are combined and act jointly for achieving the effects of nourishing yin, tonifying qi and resolving stagnation for tranquilization, and depression of old people is effectively treated. It is proved by clinic experiments that the medicine can safely and effectively treat depression of old people.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of old people's depression.
Background technology
Depression in old age refer to age of onset be 6O year and above patient, its generation changes relevant to old people's physiology and psychological aspects, main cause for retirement leave office, doings tail off and solitary etc.Depression in old age typical clinical symptom is that emotion is disconsolate, slowness of thinking and communication activity reduce.Although most senile patients with depressive disorder Degree of Depression is comparatively light, it still can cause serious harm to patient, and as increased patient's somatopsychic illness probability and reducing patients ' life quality etc., severe patient even causes death.
Atypical depression outbreak shows as depressed, retardation of thinking and speech event minimizing etc.The clinical symptoms Chang Butai typical case of senile depression outbreak, there are some difference with between twenty and fifty phase patient, the main suit of Cognitive function damage and Somatic discomfort is comparatively common.
Current doctor trained in Western medicine clinical treatment old people depression there is no effective way, multiselect with 1. tricyclic antidepressants 2. selective serotonin reuptake inhibitor as fluoxetine, paroxetine etc. 3. other novel antidepressant as venlafaxine, mirtazapine and trazodone etc.But there is side effect, certain infringement is caused to Liver and kidney.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Radix seu Herba Spiranthis Lanceae [source] the orchid family Spiranthes plant Radix seu Herba Spiranthis Lanceae Spiranthesaustralis (R.Brown.) Lindl., with root, all herbal medicine.Autumn uproots, and removing stem and leaf, cleans and dry.Spring and summer is gathered herb, cleans and dries.[nature and flavor] are sweet, light, flat.[function cures mainly] enriching yin boost qi, removing pathogenic heat from blood and toxic substance from the body.For body is empty after being ill, neurasthenia, hemoptysis of pulmonary tuberculosis, laryngopharynx swelling and pain, Infantile Summer Fever, diabetes, leucorrhea; Venom is controlled in external.[usage and dosage] root or herb 0.3 ~ 1 liang; Suitable amount used externally, deposited affected part mashed by fresh or fresh grass.
Radix Ephedrae [source] this product is the dry root and rhizome of Ephedraceae plant plait Herba Ephedrae EphedrasinicaStapf or epheday intermedia EphedraintermediaSchrenketC.A.Mey..Autumn end excavates, and removes residual stem, fibrous root and silt, dry.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung meridian.[function cures mainly] hidroschesis.For spontaneous perspiration, night sweat.[usage and dosage] 3 ~ 9g.Suitable amount used externally levigation spreads to be flutterred.
Semen Ziziphi Spinosae [source] this product is the dry mature seed of Rhamnaceae plant Ziziphi Spinosae ZiziphusjujubaMill.var.spinosa (Bunge) HuexH.F.Chou.Time of the year when autumn changes into winter gathers mature fruit, removing sarcocarp and nucleocapsid, collects seed, dries.[nature and flavor] are sweet, sour, flat.[return through] returns liver, gallbladder, heart channel.[function cures mainly] tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty.[usage and dosage] 9 ~ 15g.
Concretio Silicea Bambusae [source] this product is the dried block of juice in the bar such as grass Chinese textile bamboo BambusatextilisMcClure or schizostachyum chinense Rendle SchizostachyumchinenseRendle.Autumn, season in winter two gather.[nature and flavor] are sweet, cold.[return through] GUIXIN, Liver Channel.[function cures mainly] clear heat and eliminate phlegm, cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.[usage and dosage] 3 ~ 9g.Often enter ball, powder.
Radix Physochlainae [source] this product is the dry root of plant of Solanaceae physochlaina infundibularis (Radix Physochlainae) PhysochlainainfundibularisKuang.Spring excavates, and removing fibrous root, cleans, dry.[nature and flavor] sweet, micro-hardship, heat; Poisonous.[function cures mainly] antiasthmatic-antitussive, calms the nerves relieving convulsion.Breath with cough for cold-phlegm, palpitation and insomnia is easily shied.[usage and dosage] 0.1 ~ 0.2g.
Semen Platycladi [source] this product is the dry mature kernal of Cupressaceae plant Cacumen Platycladi Platycladusorientalis (L.) Franco.Autumn, mature seed of gathering in season in winter two, dry, and removing seed coat, collects kernel.[nature and flavor] are sweet, flat.[return through] GUIXIN, kidney, large intestine channel.[function cures mainly] tranquilizing by nourishing the heart, hidroschesis, intestine moistening.For fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation.[usage and dosage] 3 ~ 9g.
Cortex Albiziae [source] this product is the dry bark of leguminous plant Herba Albiziae AlbiziajulibrissinDurazz..Summer, Qiu Erji strip, and dry.[nature and flavor] are sweet, flat.[return through] GUIXIN, liver, lung meridian.[function cures mainly] resolving stagnation for tranquilization, promoting blood circulation and detumescence.For irritability, melancholy insomnia, lung abscess skin ulcer swells, and falls and flutters the pain of injury.[usage and dosage] 6 ~ 12g.Suitable amount used externally, grinds into powder and dresses.
Benzoinum [source] this product is the dry resin of Styracaceae plant styrax tonkinensis Craib ex Hart Styraxtonkinensis (Pierre) CraibexHart..Trunk, through naturally damaging or isolating trunk in summer, Qiu Erji, is collected the resin flowed out, is dried in the shade.[nature and flavor] are pungent, bitter, flat.[return through] GUIXIN, spleen channel.[function cures mainly] is opened and is stolen clear god, promoting flow of QI and blood, pain relieving.For apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, trusted subordinate's pain, puerperal blood faints, infantile convulsion.[usage and dosage] 0.6 ~ 1.5g, enters the loose use of ball more.
Radix Liriopes [source] this product is the dried root of liliaceous plant Hubei Liriopespicata Radix Ophiopogonis (Thunb.) Lour.var.proliferaY.T.Ma or liriope muscari Baily Liriopemuscari (Decne.) Baily.Early summer is excavated, and cleans, is repeatedly exposed to the sun, banks up, near dry, and removing fibrous root, dry.[nature and flavor] sweet, micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, cough due to consumptive disease, Tianjin wound is thirsty, vexed insomnia, dryness of the intestine constipation.[usage and dosage] 9 ~ 15g.
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of old people's depression, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing old people depression.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine being used for the treatment of old people's depression, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix seu Herba Spiranthis Lanceae 1 part, Radix Ephedrae 6 parts, Semen Ziziphi Spinosae 10 parts, Concretio Silicea Bambusae 6 parts, Radix Physochlainae 1 part, Semen Platycladi 8 parts, Cortex Albiziae 10 parts, Benzoinum 1 part, Radix Liriopes 10 parts.
Inventor thinks: anxious melancholy person, gas-tight plug and not all right.Patient's feelings will is not relaxed, depression and stagnation of QI causes to feel depressed, irritable emotion or irritability are easily cried.Enriching yin boost qi, resolving stagnation for tranquilization is focused on during treatment.
The present invention uses: Radix seu Herba Spiranthis Lanceae enriching yin boost qi; Radix Ephedrae sets aside all worries hidroschesis; Semen Ziziphi Spinosae mind calming arresting sweating; Concretio Silicea Bambusae clear heat and eliminate phlegm; Radix Physochlainae is calmed the nerves relieving convulsion; Semen Platycladi tranquilizing by nourishing the heart; Cortex Albiziae resolving stagnation for tranquilization; Benzoinum is opened and is stolen clear god; Radix Liriopes lung moistening clears away heart-fire.All medicines share, and play effect of enriching yin boost qi, resolving stagnation for tranquilization altogether, effectively treatment old people depression.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects old people's patients with depression 70 example for 2012 altogether between year December of December ~ 2014, all from Neurology Clinic, and 60 ~ 75 years old age, male 45 example, women 25 example.The course of disease 3 months ~ 3 years.
Diagnostic criteria:
All meet the diagnostic criteria of paralepsy in U.S.'s diagnostic & statistical manual the 4th edition (DSM-IV): 60 ~ 75 years old age; HAMD (HAMD) (17) total score >=20 point when entering to organize.
Exclusion standard: electroencephalogram has spike person; The physical disease persons such as severe cardiac, liver, kidney; Wine, medicine dependent; Pregnant and lactant women; Without severe physical disease; Enter to organize patient all obtained patient and family members, care provider agreement and sign Informed Consent Form.
2, test method
The decoct that the oral the present invention of all patients obtains according to embodiment 1, every day 3 times.4 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Respectively to carrying out HAMD (24) scoring 1,2,6,8 weekends before patient treatment, after treatment, apply untoward reaction scale (TESS) simultaneously and carry out untoward reaction evaluation, the average correlation coefficient of evaluation person's consistency check is 0.85.Curative effect is by 4 grades of evaluations, and deduction >=75% is recovery from illness, and deduction 50% ~ 74% is marked improvement, and 25% one 49% is progress, and deduction <25% is invalid.
3.2 therapeutic outcome
70 routine patients fully recover 47 example, marked improvement 19 example, invalid 4 example, total effective rate 94%.There is laxativeness in treatments period 2 example, has no other obvious adverse reaction.It is safe and effective that visible the present invention is used for the treatment of old people's depression, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix seu Herba Spiranthis Lanceae 1 gram, Radix Ephedrae 6 grams, Semen Ziziphi Spinosae 10 grams, Concretio Silicea Bambusae 6 grams, Radix Physochlainae 1 gram, Semen Platycladi 8 grams, Cortex Albiziae 10 grams, Benzoinum 1 gram, Radix Liriopes 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of old people's depression.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: Radix seu Herba Spiranthis Lanceae 1 gram, Radix Ephedrae 6 grams, Semen Ziziphi Spinosae 10 grams, Concretio Silicea Bambusae 6 grams, Radix Physochlainae 1 gram, Semen Platycladi 8 grams, Cortex Albiziae 10 grams, Benzoinum 1 gram, Radix Liriopes 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of old people's depression.Oral, daily once.
Embodiment 3
Take: Radix seu Herba Spiranthis Lanceae 1 gram, Radix Ephedrae 6 grams, Semen Ziziphi Spinosae 10 grams, Concretio Silicea Bambusae 6 grams, Radix Physochlainae 1 gram, Semen Platycladi 8 grams, Cortex Albiziae 10 grams, Benzoinum 1 gram, Radix Liriopes 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of old people's depression.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the medicine of old people's depression, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix seu Herba Spiranthis Lanceae 1 part, Radix Ephedrae 6 parts, Semen Ziziphi Spinosae 10 parts, Concretio Silicea Bambusae 6 parts, Radix Physochlainae 1 part, Semen Platycladi 8 parts, Cortex Albiziae 10 parts, Benzoinum 1 part, Radix Liriopes 10 parts.
2. be used for the treatment of the medicine of old people's depression as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix seu Herba Spiranthis Lanceae 1 part, Radix Ephedrae 6 parts, Semen Ziziphi Spinosae 10 parts, Concretio Silicea Bambusae 6 parts, Radix Physochlainae 1 part, Semen Platycladi 8 parts, Cortex Albiziae 10 parts, Benzoinum 1 part, Radix Liriopes 10 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the medicine of old people's depression as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix seu Herba Spiranthis Lanceae 1 part, Radix Ephedrae 6 parts, Semen Ziziphi Spinosae 10 parts, Concretio Silicea Bambusae 6 parts, Radix Physochlainae 1 part, Semen Platycladi 8 parts, Cortex Albiziae 10 parts, Benzoinum 1 part, Radix Liriopes 10 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the medicine of old people's depression as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix seu Herba Spiranthis Lanceae 1 part, Radix Ephedrae 6 parts, Semen Ziziphi Spinosae 10 parts, Concretio Silicea Bambusae 6 parts, Radix Physochlainae 1 part, Semen Platycladi 8 parts, Cortex Albiziae 10 parts, Benzoinum 1 part, Radix Liriopes 10 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Cited By (1)
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CN108635555A (en) * | 2018-06-25 | 2018-10-12 | 深圳市宝安中医院(集团) | A kind of traditional Chinese medicine acupoint emplastrum and preparation method thereof for treating depressive disorder |
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CN102824439A (en) * | 2012-09-10 | 2012-12-19 | 宁强县老羌寨生态农业发展有限责任公司 | Medicated wine capable of recuperating neurologic function |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108635555A (en) * | 2018-06-25 | 2018-10-12 | 深圳市宝安中医院(集团) | A kind of traditional Chinese medicine acupoint emplastrum and preparation method thereof for treating depressive disorder |
CN108635555B (en) * | 2018-06-25 | 2021-04-06 | 深圳市宝安中医院(集团) | A Chinese medicinal acupoint patch for treating depressive disorder, and its preparation method |
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Application publication date: 20160120 |