CN105250153A - Cream for eye skin care - Google Patents
Cream for eye skin care Download PDFInfo
- Publication number
- CN105250153A CN105250153A CN201510731063.9A CN201510731063A CN105250153A CN 105250153 A CN105250153 A CN 105250153A CN 201510731063 A CN201510731063 A CN 201510731063A CN 105250153 A CN105250153 A CN 105250153A
- Authority
- CN
- China
- Prior art keywords
- chitosan
- bioactivity glass
- skin
- mass percent
- cream
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glass Compositions (AREA)
Abstract
The invention relates to cream for eye skin care. The cream for eye skin care is prepared from the components: 1-10% of bioactive glass, 25-65% of chitosan gel and 28-65% of glycerinum, wherein the bioactive glass comprises 40-80% of SiO2, 10-36% of CaO, 1-10% of P2O5 and 9-30% of Na2O; chitosan exists in form of citrate-dissolvable gel. The cream for eye skin care is prepared from the bioactive glass, the chitosan gel and the glycerinum, wherein the chitosan can improve the immunity, retards the growth of protogenous bacteria and facilitates the healing of the injured skin; the bioactive glass completely disperses in the glycerinum; the healing of microcracks caused by skin dryness can be facilitated so as to prevent infection; the acidity of chitosan citrate gel is neutralized. In use, the bioactive glass slowly releases in the skin by taking the glycerinum as the medium to exert the functions; the glycerinum and the chitosan gel is combined to form a viscoelastic body which has dual performances of a hydrocolloid and an oily colloid.
Description
Technical field
The present invention relates to a kind of cream frost for eye part skin nursing.
Background technology
The skin of around eyes is that we open eyes, close one's eyes and oculogyral direct correlation tissue, and skin thickness only has 1/10th of common skin, and subcutaneous sebaceous gland and sweat gland distribute few, and therefore skin is thinner, loose, but elasticity is larger.
The eyes of people will blink 100,000 times every day, and circumference of eyes skin is soft and fine especially slim, and therefore its is the oldest and the most feeble, lax and occur gauffer.Very easily produce as problems such as little microgroove, wrinkle, crows-feet, eye pouch, black eye, eyes edema.
Eye cream is a kind of conventional cosmetics being used for protecting this one deck skin of around eyes.Eye cream, based on water and glycerol, adds vitamin, albumen, hyaluronate sodium, the different efficacies compositions such as antiseptic, to reach skin care, reduces black eye, eye pouch, improves effect of wrinkle, microgroove.
For the job market personage through office work of being everlasting, no matter be summer or winter, the use of air-conditioning all can make air dry especially, in the indoor long-term work of relative closure, will certainly cause xerosis cutis, the skin of circumference of eyes fragile especially especially.Skin too drying is too felt nervous and will be produced fine crack, causes skin injury.Before being sitting in computer screen for a long time, being subject to radiation and electrostatic field, to affect circumference of eyes skin the most aging and produce mottle.And research display computer is under open state, an electrostatic field around display, can be formed.This electrostatic field is easy to a large amount of suspensions arround absorption in scope.Suspension as the carrier of bacterial micro-organism descends slowly and lightly and skin to be caused on skin uncomfortable or infect.The particularly infection of circumference of eyes skin and discomfort, can have influence on eyestrain and glasses dry and astringent.
Chitosan is a kind of polysaccharose substance, there is good hydrophilic and parent Proteinaceous, allergy is not had to skin, stimulate and toxic reaction.Chitosan is easy to form protecting film, its moisture absorption at skin surface, and water retention can make skin emolliency, moistening, ductility good; Chitosan also has immunoregulatory activity, effectively can promote wound healing.
Bioactivity glass is with silicon dioxide, the blending constituent of the oxide of alkali and alkaline earth metal ions.Bioactivity glass good biocompatibility, can induced osteogenesis in human body, can be used as body bone tissue repair materials, as promise nation of U.S. artificial bone, and Shanghai promise side bioactivity glass artificial bone etc.It also more and more comes into one's own to the effect of soft tissue repair, and commercial product has skin raw, the wound repair material etc. of De Molin and Shanghai promise side.
CN1562075 discloses bioactive glass treatment gingivitis, dental hemorrhage and removes the effect of odontoseisis symptom, and bioactivity glass is by SiO
2, CaO, Na
2o, P
2o
5, B
2o
3form Deng configuration.This invention to the suppression of oral cavity bacterium and bactericidal action and to the promotion of osseous tissue and soft tissue growth and wound healing effect, is used for treatment gingivitis, dental hemorrhage and remove odontoseisis symptom according to bioactivity glass.So far also bioactivity glass is not used for the document of eye cream.
Summary of the invention
The present invention seeks to, for above-mentioned present situation, to aim to provide one and there is antimicrobial, repair the cream frost for eye part skin nursing of skin injury effect.
The implementation of the object of the invention is: for the cream frost of eye part skin nursing, formed by bioactivity glass, chitosan gel rubber and glycerol, the mass percent of each several part is: bioactivity glass 1%-10%, chitosan gel rubber 25%-65%, glycerol 28%-65%;
The mass percent of each several part of described bioactivity glass is: SiO
240%-80%, CaO10%-36%, P
2o
51%-10%;
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
The present invention adopts bioactivity glass, chitosan gel rubber and glycerol, and chitosan can increase human body causes infection immunity to antibacterial, fungus, hinders probiotics growth, not only can not cause infection that it also can be impelled to heal to the skin of damage; Bioactivity glass can fully disperse in glycerol; Bioactivity glass, to the damage of the micro-crack shape caused due to xerosis cutis, can accelerate healing, the infection that can skin can be stoped to occur; Can in and the acidity of Chitosan citrate. gel.
In use procedure of the present invention, bioactivity glass is play a role in medium slow release to skin with glycerol; Glycerol and the extraordinary combination of chitosan gel rubber, have the duality of hydrocolloid and factice body in conjunction with the viscoelastic body formed.
Detailed description of the invention
The present invention is formed by bioactivity glass, chitosan gel rubber and glycerol, and the mass percent of each several part is: bioactivity glass 0.1%-10%, chitosan gel rubber 25%-65%, glycerol 25%-65%.Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
Preferably, the mass percent of bioactivity glass is: 3%-8%.Test proves, this proportioning of bioactivity glass, physical and chemical performance and effect are desirable.Especially 7%, the best result of use of bioactivity glass can be played.
The mass percent of each several part of described bioactivity glass is: SiO
240%-80%, CaO10%-36%, P
2o
51%-10%.Preferably, the mass percent of each several part of bioactivity glass is: SiO
240%-60%, CaO24.5%-36%, P
2o
54%-6%.Preferred, the mass percent of each several part of bioactivity glass is: SiO
260%, CaO36%, P
2o
54%.This kind of bioactivity glass is called 58s sol-gel bioglass.
Bioactivity glass also has Na
2o, has Na
2the mass percent of each several part of the bioactivity glass of O is: SiO
240%-80%, CaO10%-40%, Na
2o9%-30%, P
2o
51%-10%.
Preferably, the mass percent of each several part of bioactivity glass is: SiO
240%-60%, CaO24%-36%, Na
2o10%-24.5%, P
2o
54%-8%.This bioactivity glass is often referred to as 45S5 bioactivity glass.
The effect of 58s sol-gel bioglass, 5S5 bioactivity glass antibiotic property and damaged tissue repair is more excellent.
The granule of bioactivity glass is less than 10 microns.Bioactivity glass exists with short grained pattern, and especially below 10 microns, powder adds in cream frost, can be conducive to fully disperseing fast and guaranteeing that the sense of touch of cream frost is fine and smooth of powder.
Embodiment 1, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 7%, chitosan gel rubber 65%, glycerol 28%;
The mass percent of each several part of described bioactivity glass is: SiO
245%, CaO24.5%, Na
2o24.5%, P
2o
56%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
The present embodiment has extraordinary anti-microbial property, can protect from infection, and can promote the healing of skin surface micro-crack.
Embodiment 2, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 5%, chitosan gel rubber 65%, glycerol 30%;
The mass percent of each several part of described bioactivity glass is: SiO
260%, CaO36%, P
2o
54%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
The present embodiment anti-microbial property is good, can promote the healing of skin surface micro-damage.
Embodiment 3, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 7%, chitosan gel rubber 65%, glycerol 28%;
The mass percent of each several part of described bioactivity glass is: SiO
240%, CaO20%, Na
2o30%, P
2o
510%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
Embodiment 4, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 7%, chitosan gel rubber 65%, glycerol 28%;
The mass percent of each several part of described bioactivity glass is: SiO
280%, CaO10%, Na
2o9%, P
2o
51%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
Embodiment 5, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 10%, chitosan gel rubber 25%, glycerol 65%;
The mass percent of each several part of described bioactivity glass is: SiO
245%, CaO24.5%, Na
2o24.5%, P
2o
56%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
Embodiment 6, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 1%, chitosan gel rubber 65%, glycerol 34%;
The mass percent of each several part of described bioactivity glass is: SiO
260%, CaO36%, Na
2o9%, P
2o
54%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
The present embodiment anti-microbial property is good, can promote the healing of skin surface micro-damage.
Embodiment 7, formed by the bioactive glass powder, chitosan gel rubber and the glycerol that are less than 10 microns, the mass percent of each several part is: bioactivity glass 10%, chitosan gel rubber 25%, glycerol 65%;
The mass percent of each several part of described bioactivity glass is: SiO
260%, CaO36%, P
2o
54%.
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
The present embodiment anti-microbial property is good, can promote the healing of skin surface micro-damage.
The present invention is on probation, and trial state is as follows:
Example 1 on probation, experimenter Zhao so-and-so, women, 36 years old, there is a lot of microgroove at canthus, local is coated on the skin twice of circumference of eyes every day with the cream frost for eye part skin nursing in use the embodiment 1 of freckle, and the microgroove at one week rear discovery canthus obviously reduces, and freckle also subtracts light to some extent.Continue use one month, dermal sensation is more smooth, and the situation before using does not appear in the microgroove at canthus and freckle.
Example 2 on probation, the experimenter Qin, female, 29 years old, circumference of eyes skin rubefaction, the cream frost for eye part skin nursing of the use embodiment 1 of pruritus pain is treated; Use after washing one's face once, after twice use, rubescently obviously to alleviate, pruritus and pain disappear after alleviating gradually completely at every turn.
Example 3 on probation, experimenter Lee, man, 36 years old, circumference of eyes skin had scratch, had kermesinus scar stricture of vagina after healing.Use the cream frost for eye part skin nursing of embodiment 2 to treat, smear rear massaging skin before sleeping every night 5 minutes, after continuously using two weeks, scar tissue color is thin out, scar tissue by firmly turning soft, face's image be improved significantly.
Claims (7)
1., for the cream frost of eye part skin nursing, it is characterized in that: formed by bioactivity glass, chitosan gel rubber and glycerol, the mass percent of each several part is: bioactivity glass 1%-10%, chitosan gel rubber 25%-65%, glycerol 28%-65%;
The mass percent of each several part of described bioactivity glass is: SiO
240%-80%, CaO10%-36%, P
2o
51%-10%;
Described chitosan is the chitosan of the gel pattern existence being dissolved in citrate.
2. the cream frost for eye part skin nursing according to claim 1, is characterized in that: bioactivity glass also has Na
2o, has Na
2the mass percent of each several part of the bioactivity glass of O is: SiO
240%-80%, CaO10%-40%, Na
2o9%-30%, P
2o
51%-10%.
3. the cream frost for eye part skin nursing according to claim 1, is characterized in that: the mass percent of bioactivity glass is: 2%-8%.
4. the cream frost for eye part skin nursing according to claim 1 and 2, is characterized in that: the mass percent of each several part of bioactivity glass is: SiO
240%-60%, CaO24.5%-36%, Na
2o10%-24.5%, P
2o
54%-6%.
5. the cream frost for eye part skin nursing according to claim 1, is characterized in that: the mass percent of each several part of bioactivity glass is: SiO
260%, CaO36%, P
2o
54%.
6. the cream frost for eye part skin nursing according to claim 1 and 2, is characterized in that: the mass percent of each several part of bioactivity glass is: SiO
245%, CaO24.5%, Na
2o24.5%, P
2o
56%.
7. the cream frost for eye part skin nursing according to claim 1, is characterized in that: the granule of bioactivity glass is less than 10 microns.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510731063.9A CN105250153A (en) | 2015-10-30 | 2015-10-30 | Cream for eye skin care |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510731063.9A CN105250153A (en) | 2015-10-30 | 2015-10-30 | Cream for eye skin care |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105250153A true CN105250153A (en) | 2016-01-20 |
Family
ID=55090299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510731063.9A Pending CN105250153A (en) | 2015-10-30 | 2015-10-30 | Cream for eye skin care |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105250153A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108434023A (en) * | 2018-06-13 | 2018-08-24 | 广东海洋大学 | It is a kind of can strengthen immunity cosmetics manufacture craft |
| CN110507558A (en) * | 2019-09-20 | 2019-11-29 | 成都迪康中科生物医学材料有限公司 | A kind of wound repair hyaluronic acid facial mask liquid and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101522164A (en) * | 2006-09-13 | 2009-09-02 | 提升肤质产品公司 | Cosmetic composition for the treatment of skin and methods thereof |
| CN103040729A (en) * | 2013-02-03 | 2013-04-17 | 福州乾正药业有限公司 | Chitosan gel for removing acne scars as well as preparation method and medical application thereof |
| CN103143054A (en) * | 2011-12-06 | 2013-06-12 | 贵州金玖生物技术有限公司 | Anti-inflammatory hydrocolloid dressing capable of promoting wound healing |
| CN103989608A (en) * | 2014-03-20 | 2014-08-20 | 广州市博卡利生物科技有限公司 | Chitosan temperature-sensitive gel aloe mask |
| CN104207960A (en) * | 2013-06-05 | 2014-12-17 | 上海诺帮生物科技有限公司 | Toothpaste containing bioactive glass/chitosan |
-
2015
- 2015-10-30 CN CN201510731063.9A patent/CN105250153A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101522164A (en) * | 2006-09-13 | 2009-09-02 | 提升肤质产品公司 | Cosmetic composition for the treatment of skin and methods thereof |
| CN103143054A (en) * | 2011-12-06 | 2013-06-12 | 贵州金玖生物技术有限公司 | Anti-inflammatory hydrocolloid dressing capable of promoting wound healing |
| CN103040729A (en) * | 2013-02-03 | 2013-04-17 | 福州乾正药业有限公司 | Chitosan gel for removing acne scars as well as preparation method and medical application thereof |
| CN104207960A (en) * | 2013-06-05 | 2014-12-17 | 上海诺帮生物科技有限公司 | Toothpaste containing bioactive glass/chitosan |
| CN103989608A (en) * | 2014-03-20 | 2014-08-20 | 广州市博卡利生物科技有限公司 | Chitosan temperature-sensitive gel aloe mask |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108434023A (en) * | 2018-06-13 | 2018-08-24 | 广东海洋大学 | It is a kind of can strengthen immunity cosmetics manufacture craft |
| CN110507558A (en) * | 2019-09-20 | 2019-11-29 | 成都迪康中科生物医学材料有限公司 | A kind of wound repair hyaluronic acid facial mask liquid and preparation method thereof |
| CN110507558B (en) * | 2019-09-20 | 2020-08-28 | 成都迪康中科生物医学材料有限公司 | Wound repair hyaluronic acid mask liquid and preparation method thereof |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160120 |
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| WD01 | Invention patent application deemed withdrawn after publication |