CN105232792A

CN105232792A - Medicine liquid for treating burn and scald and preparation method thereof

Info

Publication number: CN105232792A
Application number: CN201510794877.7A
Authority: CN
Inventors: 成文星
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-18
Filing date: 2015-11-18
Publication date: 2016-01-13

Abstract

The invention discloses a medicine liquid for treating burn and scald and a preparation method thereof, belongs to the technical field of medicines and relates to a medicine for treating burn and scald. The medicine liquid for treating burnt and scald is prepared from the following raw material drugs in parts by weight: 3-4 parts of Chinese arborvitae root-bark, 3-4 parts of Chinese weeping cypress leaf, 2-3 parts of winter plum, 2-3 parts of Polygonum filiforme Th., 1-3 parts of cassia twig, 1-3 parts of spinyleaf pricklyash root, and 1-2 parts of subprostrate sophora. The medicine can effectively relieve pains, has the effects of clearing away heat and toxic materials, astringing dampness and sores, promoting repairing and self-growing of skin and muscles, reducing scars and accelerating healing, has low cost and rapid action, and has effective rate up to 100%.

Description

A kind of medicinal liquid for the treatment of burn and preparation method thereof

Technical field

The invention belongs to medical art, relate to the medicine for the treatment of empyrosis, be specifically related to a kind of medicinal liquid for the treatment of burn, the invention still further relates to the preparation method of this medicinal liquid.

Background technology

Empyrosis is one of unexpected injury common in people's daily life, causes skin acute injury and cause by thermodynamic activity in human body, and its thermal source comprises flame, electric pry-oil, hot water, steam, chemical burn, solid are burnt.

Because burn and scald can make normal skin antimicrobial natural barrier defence capability be damaged, so not only having an intense pain of patient can be caused, and easily cause injured wound surface more and more darker, accompanying infection, thus cause the internal injury of patient, therefore must carry out process treatment process correct in time to burn and scald.

Existing treatment burn and scald technology, mostly adopts that anesthesia relieves the pain, the western medicine of hormone, antibiotic, physical dryness and skin-grafting, there is treatment cycle long, the defect that cost is high, and doctor trained in Western medicine generally all ignores the complication that burn and scald may cause, and cures the symptoms, not the disease.The a gang of employing spraying method of traditional Chinese medical science means of existing treatment burn and scald, makes ointment or powder by Chinese medicine, but inconvenience is smeared in existence, the shortcoming of easy contaminated material, and existing medicine does not generally have analgesic effect, needs to take analgesic in addition, and it is slow to take effect, the shortcoming that treatment cycle is long.

Summary of the invention

The object of the present invention is to provide a kind of medicinal liquid for the treatment of burn.

Another object of the present invention is to provide the preparation method of above-mentioned treatment burn medicinal liquid.

The present invention is achieved by the following technical solutions:

Treat a medicinal liquid for burn, prepared by the crude drug of following weight portion:

Cortex Biotae Radicis 3 ~ 4 Cacumen Cupressi 3 ~ 4 winter ground prunus mume (sieb.) sieb.et zucc. 2 ~ 3

Careless 2 ~ 3 Ramulus Cinnamomi 1 ~ 3 Radix Zanthoxyli Spinifoliis 1 ~ 3 through walls

Radix Sophorae Tonkinensis 1 ~ 2.

Further, the medicinal liquid of above-mentioned treatment burn, is prepared by the crude drug of following weight portion:

Cortex Biotae Radicis 3.5 Cacumen Cupressi 3 winter ground prunus mume (sieb.) sieb.et zucc. 2.5

Careless 2.5 Ramulus Cinnamomi 2 Radix Zanthoxyli Spinifoliis 2 through walls

Radix Sophorae Tonkinensis 1.5.

The preparation method of above-mentioned treatment wound, scald medicinal liquid, comprises the following steps:

By Cortex Biotae Radicis, Cacumen Cupressi, the winter ground prunus mume (sieb.) sieb.et zucc., grass through walls, Ramulus Cinnamomi, Radix Zanthoxyli Spinifolii, after Radix Sophorae Tonkinensis cleaning, drying, co-grinding obtains crude drug, then decoct with water 2-3 time, reclaim decocting liquid, the ethanol of 2-3 volume is added in filtering residue, soak filtered and recycled filtrate after 6-8 days, then add cyclodextrin stabilizing agent by after decocting liquid and filtrate mixing, to obtain final product.

The concentration of described ethanol is 50 ~ 70%.

Described ethanol 54 ~ 60 ° of Chinese liquor replace.

During use, be covered on injury after first being soaked with this medicinal liquid by absorbent cotton, at once just can play analgesic effect, and antiinflammatory can be carried out to injury; After preliminary treatment, belong to I, II degree of wound surface if injured, can, by medicinal liquid direct spraying in injured wound surface, use to take effect the same day; If injured relatively serious, belong to III degree of wound surface, then need absorbent cotton to be fixed on wound surface, every time spraying, keep absorbent cotton moistening, then 3 days can take effect.

In raw material of Chinese medicine of the present invention: Cacumen Cupressi cures mainly dysentery, spit blood, hemorrhoid, scald, hemostasia and promoting granulation, control knife injury, Cortex Biotae Radicis has hemostasia and promoting granulation, effect of anti-inflammatory analgetic, cure mainly the bright scald of fire, rotten skin ulcer, winter ground prunus mume (sieb.) sieb.et zucc. have another name called Radix clerodendri fragrantis (Radix Clerodendri Philippini), there is expelling wind and removing dampness, detumescence, the effect of blood pressure lowering, cure mainly rheumatic ostalgia, beriberi edema, chronic osteomyelitis, wash the lazy swelling due to wind of scabies, grass through walls and Herba Lysimachiae, there are promoting the circulation of QI to relieve pain, removing toxic substances sandworm, depressed stasis of blood pain, the effect of dissipating blood stasis for subsidence of swelling, Ramulus Cinnamomi can be antibacterial, antiviral, diaphoresis expelling pathogenic factors from muscles, profit passages through which vital energy circulates joint, Radix Zanthoxyli Spinifolii can expelling wind and cold, relaxing muscles and tendons to promote blood circulation, analgesia, Radix Sophorae Tonkinensis has heat-clearing and toxic substances removing, effect of detumescence.

In prescription of the present invention, monarch drug is Cortex Biotae Radicis, Cacumen Cupressi, and one works plays the effect of hemostasia and promoting granulation, anti-inflammatory analgetic; Ministerial drug be the winter ground prunus mume (sieb.) sieb.et zucc., grass through walls, play damp eliminating detumescence, effect of blood pressure lowering promoting the circulation of QI to relieve pain; Adjuvant drug is Ramulus Cinnamomi, Radix Zanthoxyli Spinifolii, increases anti-inflammation, the analgesic drug effect of medicine; Medicine is made to be Radix Sophorae Tonkinensis, to strengthen the effect of medicine heat-clearing and toxic substances removing, detumescence further.

In prescription of the present invention, containing the lignanoids, flavonoid, the sesquiterpenoids chemical composition that are soluble in organic solution in Cacumen Cupressi and Cortex Biotae Radicis, to decoct and after using soak with ethanol crude drug, these effective ingredient are dissolved in decocting liquid and alcoholic solution, be sprayed on wound surface, play the effect of blood activating and promoting tissue regeneration, anti-inflammatory analgetic; Winter ground prunus mume (sieb.) sieb.et zucc. and grass through walls in the composition such as flavonoid glycoside, phenols, Saponin, tannin that is rich in, decoct and after extracting its effective ingredient by soak with ethanol, act on wound surface, can on the basis of Cacumen Cupressi and Cortex Biotae Radicis effect, play heat-clearing and toxic substances removing, the effect of inducing diuresis to remove edema; And the effective ingredient in Ramulus Cinnamomi is dissolved in solution, from outward appearance to inner essence, antibacterial, antiviral effect can be played.

The beneficial effect that the present invention produces is further illustrated below from clinical practice result:

One, patient data

Choose patient 100 example in year April in April, 2012 to 2015, the age, at 2 years old-75 years old, is divided into experimental group and matched group at random, often organizes 50 people.

Wherein experimental group 50 example, man 27 example, female 23 example, matched group 50 example, man 24 example, female 26 example.

Traumatogenic reason: burn 44 example, boiling water burn 36 example, deep fat scald 9 example, Caustic soda chemical burn 6 example, electric spark burn 5 example.

Burn grade: I degree of 51 people, II degree of 37 people, III degree of 12 people,

Wherein, I degree of burn and scald: only injure epidermal area, injured skin rubefaction, swelling, feel smartly bitterly, but anhydrous bubbling out shows;

II degree of burn and scald: injure skin corium, local is red and swollen, heating, and hurt like hell, has obvious blister;

III degree of burn and scald: full thickness skin fat, bone and the muscle comprised below skin is all subject to imitative evil, and skin is burned black, downright bad, at this moment pain is inviolent on the contrary, because many nerves are also damaged all together.

Two, Therapeutic Method

Experimental group uses medicinal liquid of the present invention, and matched group uses commercially available Tang Wang Shi Scald Ointment.

Three, standard is treated

Cure: wound surface all healed, without residual wound;

Basic healing: wound surface heals substantially, still have some deficits 1% residual wound, without the need to operation, changes dressings can heal through a period of time;

Take a turn for the better: wound surface large portion healing, but residual wound surface is more than more than 1%, surgery skin grafting of still needing;

Do not heal: the large portion of wound surface exists.

Four, therapeutic outcome

Result of the test in table 1,

Table 1

Project	Cure	Basic healing	Take a turn for the better	Do not heal	Antalgica	Effective percentage (%)
							Experimental group	36	12	2	0	Do not use	100
Matched group	34	8	4	4	20 examples use	92

As can be seen from Table 1, medicine effective percentage of the present invention reaches 100%, and patient does not need to use antalgica in addition, and in addition, medicine instant effect of the present invention, use wound surface on the same day will take an evident turn for the better.

Result of the test shows, medicine of the present invention can effective alleviating pain, and play heat-clearing and toxic substances removing, removing dampness sore, promote that skin and flesh repairs spontaneous, to reduce cicatrix, healing acceleration effect, cost is low, instant effect, and effective percentage can reach 100%.

Detailed description of the invention

Embodiment 1

By 3.5Kg Cortex Biotae Radicis, 3Kg Cacumen Cupressi, the 2.5Kg winter ground prunus mume (sieb.) sieb.et zucc., 2.5Kg grass through walls, 2Kg Ramulus Cinnamomi, 2Kg Radix Zanthoxyli Spinifolii, after 1.5Kg Radix Sophorae Tonkinensis cleaning, drying, co-grinding obtains crude drug, then 3 times are decocted with water, reclaim decocting liquid, the ethanol of 3 volumes is added in filtering residue, soak filtered and recycled filtrate after 6 days, then add cyclodextrin stabilizing agent by after decocting liquid and filtrate mixing, to obtain final product.

Embodiment 2

By 3Kg Cortex Biotae Radicis, 4Kg Cacumen Cupressi, the 2.5Kg winter ground prunus mume (sieb.) sieb.et zucc., 2Kg grass through walls, 1Kg Ramulus Cinnamomi, 3Kg Radix Zanthoxyli Spinifolii, after 1Kg Radix Sophorae Tonkinensis cleaning, drying, co-grinding obtains crude drug, then 3 times are decocted with water, reclaim decocting liquid, the concentration adding 2 volumes in filtering residue is the ethanol of 50 ~ 70%, soak filtered and recycled filtrate after 8 days, then add cyclodextrin stabilizing agent by after decocting liquid and filtrate mixing, to obtain final product.

Described ethanol 54 ~ 60 ° of Chinese liquor replace.

Embodiment 3

By 3.5Kg Cortex Biotae Radicis, 3.5Kg Cacumen Cupressi, the 3Kg winter ground prunus mume (sieb.) sieb.et zucc., 3Kg grass through walls, 2.5Kg Ramulus Cinnamomi, 1Kg Radix Zanthoxyli Spinifolii, after 1.3Kg Radix Sophorae Tonkinensis cleaning, drying, co-grinding obtains crude drug, then 3 times are decocted with water, reclaim decocting liquid, the ethanol of 3 volumes is added in filtering residue, soak filtered and recycled filtrate after 7 days, then add cyclodextrin stabilizing agent by after decocting liquid and filtrate mixing, to obtain final product.

Embodiment 4

By 4Kg Cortex Biotae Radicis, 3.5Kg Cacumen Cupressi, the 2Kg winter ground prunus mume (sieb.) sieb.et zucc., 2.5Kg grass through walls, 3Kg Ramulus Cinnamomi, 2.5Kg Radix Zanthoxyli Spinifolii, after 1.6Kg Radix Sophorae Tonkinensis cleaning, drying, co-grinding obtains crude drug, then 2 times are decocted with water, reclaim decocting liquid, 54 ~ 60 ° of Chinese liquor of 2 volumes are added in filtering residue, soak filtered and recycled filtrate after 6 days, then add cyclodextrin stabilizing agent by after decocting liquid and filtrate mixing, to obtain final product.

Claims

1. treat a medicinal liquid for burn, it is characterized in that, prepared by the crude drug of following weight portion:

Radix Sophorae Tonkinensis 1 ~ 2.

2. a kind of medicinal liquid for the treatment of burn according to claim 1, is characterized in that, prepared by the crude drug of following weight portion:

Careless 2.5 Ramulus Cinnamomi 2 Radix Zanthoxyli Spinifoliis 2 through walls

Radix Sophorae Tonkinensis 1.5.

3. the treatment wound described in claim 1 or 2, the preparation method of scald medicinal liquid, is characterized in that, comprise the following steps:

4. the preparation method of the medicinal liquid for the treatment of burn according to claim 3, is characterized in that, the concentration of described ethanol is 50 ~ 70%.

5. the preparation method of the medicinal liquid for the treatment of burn according to claim 3, is characterized in that, described ethanol 54 ~ 60 ° of Chinese liquor replace.